| Tag |
Content |
| WERAM ID |
WERAM-Mum-0029 |
| Ensembl Protein ID |
ENSMUSP00000019911.7 |
| Uniprot Accession |
A0A0R4J008; A0A0R4J008_MOUSE
|
| Genbank Protein ID |
NP_032255.2
|
| Protein Name |
Histone deacetylase |
| Genbank Nucleotide ID |
NM_008229.2
|
| Gene Name |
HDAC2 |
| Ensembl Information |
|
| Details |
| Type |
Family |
Domain |
Substrates |
AA |
References (PMIDs) |
| HDAC |
Class-I |
Hist_deacetyl |
H2A; H2B; H3; H4 |
K |
18292778
|
|
| Status |
Reviewed |
| Classification |
| Type |
Family |
E-value |
Score |
Start |
End |
| HDAC |
Class-I |
9.60e-175 |
582 |
10 |
321 |
|
| Organism |
Mus musculus |
| NCBI Taxa ID |
10090 |
Functional Description
(View) |
|
| Domain Profile |
HDAC Class-I
class-1.txt 1 kkvayaydedvgeyhygqkhpmkpkrlsltheLvlnyglskkleivkpkkasaeellkfhseeyieflkkvepenaeelskelkkfnvg 89
kkv+y+yd d+g+y+ygq+hpmkp+r+++th+L+lnygl++k+ei++p+ka+aee++k+hs+eyi+fl++++p+n++e+sk++++fnvg
ENSMUSP00000019911.7 10 KKVCYYYDGDIGNYYYGQGHPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKATAEEMTKYHSDEYIKFLRSIRPDNMSEYSKQMQRFNVG 98
589************************************************************************************** PP
class-1.txt 90 edcPvfdglfeycqlitGasleaakkLnkkeadiainwaGGlhhakkseasGfcyvnDivlailellkkhkrvlyididlhhGDgveea 178
edcPvfdglfe+cql+tG+s+++a kLn++++d+a+nwaGGlhhakkseasGfcyvnDivlailellk+h+rvlyidid+hhGDgveea
ENSMUSP00000019911.7 99 EDCPVFDGLFEFCQLSTGGSVAGAVKLNRQQTDMAVNWAGGLHHAKKSEASGFCYVNDIVLAILELLKYHQRVLYIDIDIHHGDGVEEA 187
***************************************************************************************** PP
class-1.txt 179 fyttdrvmtvsfhkygeeffPgtGdlsdvgaekgkyyavnvPlkdgidDesyekifksviskvieafePeavvlqcGaDslagDrlgef 267
fyttdrvmtvsfhkyge +fPgtGdl+d+ga+kgkyyavn+P++dgidDesy +ifk++iskv+e+++P+avvlqcGaDsl+gDrlg+f
ENSMUSP00000019911.7 188 FYTTDRVMTVSFHKYGE-YFPGTGDLRDIGAGKGKYYAVNFPMRDGIDDESYGQIFKPIISKVMEMYQPSAVVLQCGADSLSGDRLGCF 275
*****************.*********************************************************************** PP
class-1.txt 268 nlsikghaecvkfvksfnlpllvlGGGGYtlrnvaRcwtyetavvl 313
nl++kgha+cv++vk+fnlpll+lGGGGYt+rnvaRcwtyetav+l
ENSMUSP00000019911.7 276 NLTVKGHAKCVEVVKTFNLPLLMLGGGGYTIRNVARCWTYETAVAL 321
*******************************************987 PP
|
Protein Sequence
(Fasta) | MAYSQGGGKK KVCYYYDGDI GNYYYGQGHP MKPHRIRMTH NLLLNYGLYR KMEIYRPHKA 60
TAEEMTKYHS DEYIKFLRSI RPDNMSEYSK QMQRFNVGED CPVFDGLFEF CQLSTGGSVA 120
GAVKLNRQQT DMAVNWAGGL HHAKKSEASG FCYVNDIVLA ILELLKYHQR VLYIDIDIHH 180
GDGVEEAFYT TDRVMTVSFH KYGEYFPGTG DLRDIGAGKG KYYAVNFPMR DGIDDESYGQ 240
IFKPIISKVM EMYQPSAVVL QCGADSLSGD RLGCFNLTVK GHAKCVEVVK TFNLPLLMLG 300
GGGYTIRNVA RCWTYETAVA LDCEIPNELP YNDYFEYFGP DFKLHISPSN MTNQNTPEYM 360
EKIKQRLFEN LRMLPHAPGV QMQAIPEDAV HEDSGDEDGE DPDKRISIRA SDKRIACDEE 420
FSDSEDEGEG GRRNVADHKK GAKKARIEED KKETEDKKTD VKEEDKSKDN SGEKTDPKGA 480
KSEQLSNP 488Protein Fasta Sequence
>ENSMUSP00000019911.7|HDAC2|Mus musculus
MAYSQGGGKKKVCYYYDGDIGNYYYGQGHPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKATAEEMTKYHSDEYIKFLRSIRPDNMSEYSKQMQRFNVGEDCPVFDGLFEFCQLSTGGSVAGAVKLNRQQTDMAVNWAGGLHHAKKSEASGFCYVNDIVLAILELLKYHQRVLYIDIDIHHGDGVEEAFYTTDRVMTVSFHKYGEYFPGTGDLRDIGAGKGKYYAVNFPMRDGIDDESYGQIFKPIISKVMEMYQPSAVVLQCGADSLSGDRLGCFNLTVKGHAKCVEVVKTFNLPLLMLGGGGYTIRNVARCWTYETAVALDCEIPNELPYNDYFEYFGPDFKLHISPSNMTNQNTPEYMEKIKQRLFENLRMLPHAPGVQMQAIPEDAVHEDSGDEDGEDPDKRISIRASDKRIACDEEFSDSEDEGEGGRRNVADHKKGAKKARIEEDKKETEDKKTDVKEEDKSKDNSGEKTDPKGAKSEQLSNP |
Nucleotide Sequence
(Fasta) | GCCGAGTGTC GCGCGTCGGC GCCGCTGCCT ATCCCGCTCT GTGCCCTACG GCCCTCCCGG 60
CACCCGCCGC CGTCCCGCTC CGGGCTGCCC TTGCTCCGAG GGCTGCAGCA CCGGCCGTCC 120
CCGTCAGCCC TCTTGTCTGG CCGCCGGGCC GCGGCGGGCG GGAGCAGCCG GAGGAGGAGC 180
CGCAGCCGGG AGGCGGCGGC CTGAGCCCAT GGCGTACAGT CAAGGAGGCG GCAAGAAGAA 240
AGTGTGCTAC TACTATGATG GTGATATTGG CAATTATTAT TATGGCCAGG GTCATCCCAT 300
GAAGCCTCAT AGAATCCGGA TGACTCATAA CTTGCTGCTA AATTATGGTT TATACCGAAA 360
AATGGAAATA TATAGGCCTC ATAAAGCCAC TGCTGAAGAA ATGACTAAAT ACCACAGCGA 420
TGAGTATATC AAGTTTCTAC GATCAATAAG ACCAGATAAT ATGTCTGAGT ACAGTAAGCA 480
GATGCAGAGA TTTAACGTCG GAGAAGATTG TCCGGTGTTT GATGGACTCT TTGAGTTTTG 540
TCAGCTCTCC ACGGGTGGTT CAGTTGCTGG GGCTGTGAAA TTAAACCGGC AACAAACTGA 600
TATGGCTGTC AATTGGGCTG GAGGACTACA TCATGCCAAG AAGTCAGAAG CATCAGGGTT 660
CTGCTATGTT AATGATATTG TGCTTGCCAT CCTCGAATTA CTTAAGTATC ATCAGAGAGT 720
CTTATATATT GACATAGACA TCCACCATGG TGATGGTGTT GAGGAAGCTT TTTATACAAC 780
AGATCGCGTG ATGACCGTCT CATTCCATAA ATATGGGGAA TACTTTCCTG GAACAGGAGA 840
CTTGAGGGAT ATTGGTGCTG GAAAGGGAAA ATACTATGCT GTCAATTTTC CCATGAGAGA 900
TGGTATAGAT GATGAATCAT ATGGACAAAT TTTTAAGCCT ATCATCTCAA AAGTGATGGA 960
GATGTACCAG CCTAGCGCGG TGGTGCTGCA GTGTGGCGCA GACTCCCTGT CTGGGGACAG 1020
GCTTGGTTGT TTCAATCTAA CTGTCAAAGG TCATGCTAAA TGTGTAGAAG TAGTGAAAAC 1080
TTTTAACTTG CCATTGCTGA TGCTCGGTGG AGGAGGCTAC ACAATCCGGA ATGTTGCCCG 1140
ATGTTGGACA TATGAGACTG CAGTTGCCCT TGATTGTGAA ATTCCCAATG AGTTGCCATA 1200
TAATGATTAC TTTGAGTATT TTGGACCAGA CTTCAAACTG CATATTAGTC CTTCAAACAT 1260
GACAAACCAG AACACTCCAG AATATATGGA AAAGATAAAA CAGCGTTTAT TTGAAAATCT 1320
ACGTATGTTA CCACATGCAC CTGGTGTTCA AATGCAAGCT ATTCCAGAGG ATGCTGTTCA 1380
TGAAGACAGT GGAGATGAGG ATGGAGAAGA CCCGGACAAA AGAATTTCCA TTCGAGCATC 1440
AGACAAACGG ATAGCTTGCG ATGAAGAGTT TTCAGATTCT GAGGATGAAG GTGAAGGAGG 1500
TCGTAGGAAT GTTGCTGATC ATAAGAAAGG AGCAAAGAAG GCTAGGATTG AAGAAGACAA 1560
GAAGGAGACA GAGGACAAGA AGACAGATGT TAAGGAAGAA GACAAATCCA AGGACAATAG 1620
TGGTGAGAAA ACAGACCCCA AAGGAGCCAA GTCAGAACAA CTCAGCAACC CTTGAATTTG 1680
ACTCTCCAAC TTTAGGAACC TCGAAAAGTG AGACGATTCT GGGATAAGAA ACCTTCCCTG 1740
TTTGAGGACA TTGGCTTCAT TTTATACTGT TTTGGCATGG ACTGTATTTA TTTTCAAAAT 1800
GGCTTGTTTT TGTTTTTCTT GGCAAGTTTT ATTGTGAGTT TTTCTAATTA TGAAGCAAAT 1860
TTTTTTTTCC ACCATGCTTT ATGTGATTGT ATTTAAATTG ATGTGTTATT ATGTCAAAAG 1920
CCGGATCTAT TAAAGAAACA ATTGGCCTTT CTGAGCTGAT TTTTCCATCT TTTGTAATTA 1980
TCTTTATTAA AAAATTGTAC TTGGA
2006Nucleotide Fasta Sequence
>ENSMUSP00000019911.7|Class-I|Mus musculus
GCCGAGTGTCGCGCGTCGGCGCCGCTGCCTATCCCGCTCTGTGCCCTACGGCCCTCCCGGCACCCGCCGCCGTCCCGCTCCGGGCTGCCCTTGCTCCGAGGGCTGCAGCACCGGCCGTCCCCGTCAGCCCTCTTGTCTGGCCGCCGGGCCGCGGCGGGCGGGAGCAGCCGGAGGAGGAGCCGCAGCCGGGAGGCGGCGGCCTGAGCCCATGGCGTACAGTCAAGGAGGCGGCAAGAAGAAAGTGTGCTACTACTATGATGGTGATATTGGCAATTATTATTATGGCCAGGGTCATCCCATGAAGCCTCATAGAATCCGGATGACTCATAACTTGCTGCTAAATTATGGTTTATACCGAAAAATGGAAATATATAGGCCTCATAAAGCCACTGCTGAAGAAATGACTAAATACCACAGCGATGAGTATATCAAGTTTCTACGATCAATAAGACCAGATAATATGTCTGAGTACAGTAAGCAGATGCAGAGATTTAACGTCGGAGAAGATTGTCCGGTGTTTGATGGACTCTTTGAGTTTTGTCAGCTCTCCACGGGTGGTTCAGTTGCTGGGGCTGTGAAATTAAACCGGCAACAAACTGATATGGCTGTCAATTGGGCTGGAGGACTACATCATGCCAAGAAGTCAGAAGCATCAGGGTTCTGCTATGTTAATGATATTGTGCTTGCCATCCTCGAATTACTTAAGTATCATCAGAGAGTCTTATATATTGACATAGACATCCACCATGGTGATGGTGTTGAGGAAGCTTTTTATACAACAGATCGCGTGATGACCGTCTCATTCCATAAATATGGGGAATACTTTCCTGGAACAGGAGACTTGAGGGATATTGGTGCTGGAAAGGGAAAATACTATGCTGTCAATTTTCCCATGAGAGATGGTATAGATGATGAATCATATGGACAAATTTTTAAGCCTATCATCTCAAAAGTGATGGAGATGTACCAGCCTAGCGCGGTGGTGCTGCAGTGTGGCGCAGACTCCCTGTCTGGGGACAGGCTTGGTTGTTTCAATCTAACTGTCAAAGGTCATGCTAAATGTGTAGAAGTAGTGAAAACTTTTAACTTGCCATTGCTGATGCTCGGTGGAGGAGGCTACACAATCCGGAATGTTGCCCGATGTTGGACATATGAGACTGCAGTTGCCCTTGATTGTGAAATTCCCAATGAGTTGCCATATAATGATTACTTTGAGTATTTTGGACCAGACTTCAAACTGCATATTAGTCCTTCAAACATGACAAACCAGAACACTCCAGAATATATGGAAAAGATAAAACAGCGTTTATTTGAAAATCTACGTATGTTACCACATGCACCTGGTGTTCAAATGCAAGCTATTCCAGAGGATGCTGTTCATGAAGACAGTGGAGATGAGGATGGAGAAGACCCGGACAAAAGAATTTCCATTCGAGCATCAGACAAACGGATAGCTTGCGATGAAGAGTTTTCAGATTCTGAGGATGAAGGTGAAGGAGGTCGTAGGAATGTTGCTGATCATAAGAAAGGAGCAAAGAAGGCTAGGATTGAAGAAGACAAGAAGGAGACAGAGGACAAGAAGACAGATGTTAAGGAAGAAGACAAATCCAAGGACAATAGTGGTGAGAAAACAGACCCCAAAGGAGCCAAGTCAGAACAACTCAGCAACCCTTGAATTTGACTCTCCAACTTTAGGAACCTCGAAAAGTGAGACGATTCTGGGATAAGAAACCTTCCCTGTTTGAGGACATTGGCTTCATTTTATACTGTTTTGGCATGGACTGTATTTATTTTCAAAATGGCTTGTTTTTGTTTTTCTTGGCAAGTTTTATTGTGAGTTTTTCTAATTATGAAGCAAATTTTTTTTTCCACCATGCTTTATGTGATTGTATTTAAATTGATGTGTTATTATGTCAAAAGCCGGATCTATTAAAGAAACAATTGGCCTTTCTGAGCTGATTTTTCCATCTTTTGTAATTATCTTTATTAAAAAATTGTACTTGGA
|
| Sequence Source |
Ensembl |
| Keyword |
KW-0156--Chromatin regulator
KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0539--Nucleus
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0804--Transcription
KW-0805--Transcription regulation
--
|
| Interpro |
IPR000286--His_deacetylse
IPR003084--His_deacetylse_1
IPR023801--His_deacetylse_dom
|
| PROSITE |
|
| Pfam |
PF00850--Hist_deacetyl
|
| Gene Ontology |
GO:0005634--C:nucleus
GO:0032041--F:NAD-dependent histone deacetylase activity (H3-K14 specific)
GO:0006355--P:regulation of transcription, DNA-templated
GO:0006351--P:transcription, DNA-templated
|
| Orthology |
|
| Created Date |
25-Jun-2016 |
