Tag |
Content |
WERAM ID |
WERAM-Mum-0019 |
Ensembl Protein ID |
ENSMUSP00000102770.2 |
Uniprot Accession |
Q3UJF1; Q3UJF1_MOUSE |
Genbank Protein ID |
NP_001071164.1 |
Protein Name |
Histone deacetylase |
Genbank Nucleotide ID |
NM_001077696.1 |
Gene Name |
HDAC5 |
Ensembl Information |
|
Details |
Type |
Family |
Domain |
Substrates |
AA |
References (PMIDs) |
HDAC |
Class-II |
Hist_deacetyl |
H2A; H2B; H3; H4 |
K |
18292778 |
|
Status |
Reviewed |
Classification |
Type |
Family |
E-value |
Score |
Start |
End |
HDAC |
Class-II |
7.50e-148 |
493.5 |
121 |
1016 |
HDAC |
Class-I |
2.80e-29 |
104.2 |
697 |
985 |
|
Organism |
Mus musculus |
NCBI Taxa ID |
10090 |
Functional Description (View)Functional Description
Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. |
Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.
|
Domain Profile |
HDAC Class-II
class-2.txt 12 khqaleenkekhpEk.peRiqailsrlqeagllekleelkarka 54 ++++l + +++ E+ +R q+ ++l+++ l ++l+ l+++++ ENSMUSP00000102770.2 121 QQEMLAAKRQQELEQqRQREQQRQEELEKQRLEQQLLILRNKEK 164 11122222222222202333444444444444444444444333 PP class-2.txt 2 aglvydekmlkhqaleenkekhpEkpeRiqailsrlqeagllekleelkarkatkeelqlvHseehvelletaeklekeeles.... 84 +g+vyd+ mlkhq++++n++ hpE+++Riq+i+srlqe+gll+k+e++++rkat++e+q+vHse h+ l++t+ +l++++l+s ENSMUSP00000102770.2 676 TGVVYDTFMLKHQCMCGNTHVHPEHAGRIQSIWSRLQETGLLGKCERIRGRKATLDEIQTVHSEYHTLLYGTS-PLNRQKLDSkkll 761 79**********************************************************************9.************* PP class-2.txt 85 ...............ltvdsdsiylesksikaarlavGavlelvdkvlkgelkngfavvRPPGHHaeestamGFClfnnvavaakll 156 ++vdsd++++e++s++a+r+avG+++el++kv++gelkngfa++RPPGHHaeestamGFC+fn+va++akll ENSMUSP00000102770.2 762 gpisqkmyamlpcggIGVDSDTVWNEMHSSSAVRMAVGCLVELAFKVAAGELKNGFAIIRPPGHHAEESTAMGFCFFNSVAITAKLL 848 *************************************************************************************** PP class-2.txt 157 qqklkvkkilivDwDvHhGnGtqeifykdpkvlylSlHRydkgsffpesgsgavdevgegkgegfnvNvawnggl...mgdaeylaa 240 qqkl+v k+livDwD+HhGnGtq++fy+dp+vly+SlHRyd+g+ffp gsga++evg g+g+g+nvNvaw+gg+ +gd eyl+a ENSMUSP00000102770.2 849 QQKLSVGKVLIVDWDIHHGNGTQQAFYNDPSVLYISLHRYDNGNFFP--GSGAPEEVGGGPGVGYNVNVAWTGGVdppIGDVEYLTA 933 ***********************************************..************************************** PP class-2.txt 241 frevvlpiakeFkPdlvlvsaGfDaaeg..dplgglsvtakcyatltkqllklaggrvvlvlEGGynlkaiaeaveavvkaLl 321 fr+vv+pia+eF+Pd+vlvsaGfDa+eg +plgg+svta+c+++lt+ql++laggrvvl+lEGG++l+ai++a+ea+v+aLl ENSMUSP00000102770.2 934 FRTVVMPIAQEFSPDVVLVSAGFDAVEGhlSPLGGYSVTARCFGHLTRQLMTLAGGRVVLALEGGHDLTAICDASEACVSALL 1016 ****************************99***************************************************98 PP
HDAC Class-I
class-1.txt 20 hpmkpkrlsltheLvlnyglskkleivkpkkasaeellkfhseeyieflkkvepenae.............elskelkkfnvgedc.Pv 94 hp r++ + + + + gl k e+++ +ka+ +e++++hse y ++l +p n + ++ l ++g d+ v ENSMUSP00000102770.2 697 HPEHAGRIQSIWSRLQETGLLGKCERIRGRKATLDEIQTVHSE-YHTLLYGTSPLNRQkldskkllgpisqKMYAMLPCGGIGVDSdTV 784 5666667777777777777777888888888888888777764.555555555544443434435443332222222222455555236 PP class-1.txt 95 fdglfeyc..qlitGasleaakkLnkkead..iainwaGGlhhakkseasGfcyvnDivlailellk..khkrvlyididlhhGDgvee 177 +++++ + ++ G +e a k+ +e + ai G hha s a Gfc+ n + ++ l++ + +vl +d d+hhG+g ++ ENSMUSP00000102770.2 785 WNEMHSSSavRMAVGCLVELAFKVAAGELKngFAIIRPPG-HHAEESTAMGFCFFNSVAITAKLLQQklSVGKVLIVDWDIHHGNGTQQ 872 6666655411456688888888888776552255655555.9******************998888734567***************** PP class-1.txt 178 afyttdrvmtvsfhkyge.effPgtGdlsdvgaekgkyyavnvPlkdgid....DesyekifksviskvieafePeavvlqcGaDslag 261 afy+ v+ +s+h+y++ +ffPg+G ++vg + g y vnv + g+d D +y + f++v+ ++ + f+P++v++ G D++ g ENSMUSP00000102770.2 873 AFYNDPSVLYISLHRYDNgNFFPGSGAPEEVGGGPGVGYNVNVAWTGGVDppigDVEYLTAFRTVVMPIAQEFSPDVVLVSAGFDAVEG 961 ****************8746************************99997666669********************************87 PP class-1.txt 262 ..Drlgefnlsikghaecvkfvks 283 +lg ++++ + +++ + + + ENSMUSP00000102770.2 962 hlSPLGGYSVTARCFGHLTRQLMT 985 33589*****99999987665554 PP
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Protein Sequence (Fasta) | MNSPNESADG MSGREPSLEI LPRTPLHSIP VAVEVKPVLP GAMPSSMGGG GGGSPSPVEL 60 RGALAGPMDP ALREQQLQQE LLVLKQQQQL QKQLLFAEFQ KQHDHLTRQH EVQLQKHLKQ 120 QQEMLAAKRQ QELEQQRQRE QQRQEELEKQ RLEQQLLILR NKEKSKESAI ASTEVKLRLQ 180 EFLLSKSKEP TPGGLNHSLP QHPKCWGAHH ASLDQSSPPQ SGPPGTPPSY KLPLLGPYDS 240 RDDFPLRKTA SEPNLKVRSR LKQKVAERRS SPLLRRKDGT VISTFKKRAV EITGTGPGVS 300 SVCNSAPGSG PSSPNSSHST IAENGFTGSV PNIPTEMIPQ HRALPLDSSP NQFSLYTSPS 360 LPNISLGLQA TVTVTNSHLT ASPKLSTQQE AERQALQSLR QGGTLTGKFM STSSIPGCLL 420 GVALEGDTSP HGHASLLQHV LLLEQARQQS TLIAVPLHGQ SPLVTGERVA TSMRTVGKLP 480 RHRPLSRTQS SPLPQSPQAL QQLVMQQQHQ QFLEKQKQQQ MQLGKILTKT GELSRQPTTH 540 PEETEEELTE QQEALLGEGA LTIPREGSTE SESTQEDLEE EEEEEEEEEE DCIQVKDEDG 600 ESGPDEGPDL EESSAGYKKL FADAQQLQPL QVYQAPLSLA TVPHQALGRT QSSPAAPGSM 660 KSPTDQPTVV KHLFTTGVVY DTFMLKHQCM CGNTHVHPEH AGRIQSIWSR LQETGLLGKC 720 ERIRGRKATL DEIQTVHSEY HTLLYGTSPL NRQKLDSKKL LGPISQKMYA MLPCGGIGVD 780 SDTVWNEMHS SSAVRMAVGC LVELAFKVAA GELKNGFAII RPPGHHAEES TAMGFCFFNS 840 VAITAKLLQQ KLSVGKVLIV DWDIHHGNGT QQAFYNDPSV LYISLHRYDN GNFFPGSGAP 900 EEVGGGPGVG YNVNVAWTGG VDPPIGDVEY LTAFRTVVMP IAQEFSPDVV LVSAGFDAVE 960 GHLSPLGGYS VTARCFGHLT RQLMTLAGGR VVLALEGGHD LTAICDASEA CVSALLSVEL 1020 QPLDEAVLQQ KPSVNAVATL EKVIEIQSKH WSCVQRFAAG LGCSLREAQT GEKEEAETVS 1080 AMALLSVGAE QAQAVATQEH SPRPAEEPME QEPAL 1115Protein Fasta Sequence
>ENSMUSP00000102770.2|HDAC5|Mus musculus MNSPNESADGMSGREPSLEILPRTPLHSIPVAVEVKPVLPGAMPSSMGGGGGGSPSPVELRGALAGPMDPALREQQLQQELLVLKQQQQLQKQLLFAEFQKQHDHLTRQHEVQLQKHLKQQQEMLAAKRQQELEQQRQREQQRQEELEKQRLEQQLLILRNKEKSKESAIASTEVKLRLQEFLLSKSKEPTPGGLNHSLPQHPKCWGAHHASLDQSSPPQSGPPGTPPSYKLPLLGPYDSRDDFPLRKTASEPNLKVRSRLKQKVAERRSSPLLRRKDGTVISTFKKRAVEITGTGPGVSSVCNSAPGSGPSSPNSSHSTIAENGFTGSVPNIPTEMIPQHRALPLDSSPNQFSLYTSPSLPNISLGLQATVTVTNSHLTASPKLSTQQEAERQALQSLRQGGTLTGKFMSTSSIPGCLLGVALEGDTSPHGHASLLQHVLLLEQARQQSTLIAVPLHGQSPLVTGERVATSMRTVGKLPRHRPLSRTQSSPLPQSPQALQQLVMQQQHQQFLEKQKQQQMQLGKILTKTGELSRQPTTHPEETEEELTEQQEALLGEGALTIPREGSTESESTQEDLEEEEEEEEEEEEDCIQVKDEDGESGPDEGPDLEESSAGYKKLFADAQQLQPLQVYQAPLSLATVPHQALGRTQSSPAAPGSMKSPTDQPTVVKHLFTTGVVYDTFMLKHQCMCGNTHVHPEHAGRIQSIWSRLQETGLLGKCERIRGRKATLDEIQTVHSEYHTLLYGTSPLNRQKLDSKKLLGPISQKMYAMLPCGGIGVDSDTVWNEMHSSSAVRMAVGCLVELAFKVAAGELKNGFAIIRPPGHHAEESTAMGFCFFNSVAITAKLLQQKLSVGKVLIVDWDIHHGNGTQQAFYNDPSVLYISLHRYDNGNFFPGSGAPEEVGGGPGVGYNVNVAWTGGVDPPIGDVEYLTAFRTVVMPIAQEFSPDVVLVSAGFDAVEGHLSPLGGYSVTARCFGHLTRQLMTLAGGRVVLALEGGHDLTAICDASEACVSALLSVELQPLDEAVLQQKPSVNAVATLEKVIEIQSKHWSCVQRFAAGLGCSLREAQTGEKEEAETVSAMALLSVGAEQAQAVATQEHSPRPAEEPMEQEPAL
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Nucleotide Sequence (Fasta) | GTGACGAGAG TGACGTCTCC GAATGTTGTT GTTGGTGGCG GCGGCGAGCG GAGCCGGAGG 60 AGCCGCCGCA AAGATGGAGG AGCCGTCGAG GAGGCGCTGC CGCTGCTGTT GCCGCCGCTG 120 CTGCCGCCGC CGCCCGCGAA GCCGGAGCTC GAGCCGCAGC GGGGATGCCG TTCTGAGTGC 180 CTGACTGCCT CGCCCCGCCC CGAAGGATGG CCTTGGATGG GCATTAGAGG CACTGCGGCC 240 CTGGGCTCGG GCTCCTGTCC CGTCCGTCTG TCTGTTATCG TCTGTCTCTC TTGACATCAC 300 AGCAGCTCCG CCCCCTCCCG TCCCAGCCCC CAACGTCAGC TTCCTGCAGG CCCAGAGCCG 360 GCATGAACTC TCCCAACGAG TCGGCAGATG GCATGTCAGG CCGGGAACCA TCCTTGGAAA 420 TCCTGCCACG GACTCCTCTG CACAGCATCC CTGTGGCAGT GGAGGTGAAG CCGGTGCTGC 480 CAGGAGCCAT GCCCAGCTCC ATGGGGGGTG GAGGTGGAGG TAGCCCCAGC CCCGTGGAGC 540 TTCGGGGGGC TCTGGCGGGC CCCATGGACC CTGCGCTACG GGAGCAGCAA CTGCAGCAGG 600 AGCTCCTGGT CCTCAAGCAG CAGCAGCAGC TCCAGAAGCA GCTCCTGTTC GCCGAGTTCC 660 AGAAGCAGCA CGACCACTTG ACGCGGCAGC ACGAGGTCCA GCTGCAGAAG CACCTCAAGC 720 AGCAGCAGGA GATGCTGGCG GCTAAGAGGC AGCAGGAGCT GGAGCAGCAG CGGCAGCGGG 780 AGCAGCAGCG GCAGGAGGAG CTGGAGAAAC AGCGGCTGGA GCAGCAGCTG CTCATCCTGC 840 GCAACAAGGA GAAGAGCAAA GAGAGTGCCA TCGCCAGCAC CGAGGTAAAG CTGAGGCTCC 900 AGGAATTCCT GTTGTCCAAG TCAAAGGAGC CCACGCCAGG CGGCCTCAAC CATTCCCTCC 960 CACAGCACCC CAAATGCTGG GGAGCCCACC ACGCTTCTTT GGACCAGAGT TCCCCTCCCC 1020 AGAGCGGCCC TCCTGGGACG CCTCCCTCCT ACAAATTGCC TTTGCTTGGG CCCTATGACA 1080 GCCGTGATGA CTTTCCCCTC CGTAAAACGG CCTCGGAACC CAACTTAAAA GTACGTTCGA 1140 GGCTAAAACA GAAGGTAGCC GAGAGGAGAA GCAGTCCCCT CCTGCGTCGA AAGGATGGCA 1200 CTGTTATTAG TACTTTTAAG AAGAGAGCAG TTGAGATCAC CGGCACGGGG CCTGGGGTGT 1260 CGTCCGTGTG TAACAGTGCG CCCGGCTCTG GCCCCAGCTC TCCCAACAGT TCCCACAGCA 1320 CCATCGCTGA GAACGGCTTT ACTGGCTCAG TCCCCAACAT CCCCACTGAG ATGATCCCCC 1380 AGCACCGGGC CCTCCCTCTG GACAGTTCCC CAAACCAGTT CAGCCTCTAT ACGTCTCCTT 1440 CTCTGCCCAA CATCTCCCTA GGGCTGCAGG CCACTGTCAC TGTCACCAAC TCGCACCTCA 1500 CCGCCTCCCC GAAGCTGTCA ACACAGCAGG AGGCTGAGAG GCAGGCCCTT CAGTCCCTGC 1560 GGCAGGGCGG CACACTGACC GGCAAGTTCA TGAGCACATC CTCCATCCCT GGCTGCCTGT 1620 TGGGAGTGGC ACTGGAGGGT GACACAAGCC CCCACGGGCA CGCTTCCCTG CTGCAGCACG 1680 TTTTGCTCCT GGAGCAGGCC CGGCAACAGA GCACGCTCAT AGCAGTGCCG CTCCATGGGC 1740 AGTCCCCACT GGTGACGGGT GAACGTGTGG CCACCAGCAT GAGGACGGTG GGTAAGCTCC 1800 CGAGGCACCG ACCTCTGAGC CGCACTCAGT CCTCCCCGCT GCCGCAGAGT CCCCAGGCCC 1860 TGCAGCAGCT GGTCATGCAG CAGCAGCACC AGCAGTTCCT GGAGAAGCAG AAGCAGCAGC 1920 AGATGCAGCT GGGCAAGATC CTTACCAAAA CTGGGGAGCT GTCAAGGCAG CCCACCACTC 1980 ACCCGGAGGA GACAGAAGAG GAGCTGACGG AGCAGCAGGA GGCCTTGCTG GGAGAGGGGG 2040 CCCTGACCAT TCCCCGGGAA GGCTCTACAG AAAGTGAGAG CACCCAGGAA GACCTAGAAG 2100 AGGAGGAGGA GGAGGAGGAG GAGGAAGAGG AGGACTGCAT TCAGGTCAAG GATGAGGATG 2160 GCGAGAGTGG TCCTGATGAA GGCCCTGACT TAGAAGAGTC CAGTGCTGGT TACAAAAAGT 2220 TGTTCGCAGA TGCCCAGCAG TTACAGCCCC TCCAGGTGTA CCAGGCACCC CTCAGCCTGG 2280 CCACTGTGCC TCATCAGGCC CTGGGCCGCA CCCAGTCCTC ACCTGCTGCT CCTGGGAGCA 2340 TGAAGAGCCC CACAGACCAA CCCACTGTGG TGAAGCACCT CTTCACCACA GGTGTGGTCT 2400 ATGACACGTT CATGCTGAAG CACCAGTGTA TGTGCGGAAA CACACACGTG CACCCAGAGC 2460 ACGCCGGCCG CATCCAGAGC ATCTGGTCCC GGCTGCAGGA AACTGGTCTG CTCGGCAAGT 2520 GTGAGCGGAT CCGGGGTCGT AAAGCCACAC TGGATGAAAT CCAGACCGTG CACTCTGAGT 2580 ACCACACCCT GCTCTATGGG ACCAGCCCCC TTAACCGGCA GAAGCTGGAC AGCAAGAAGC 2640 TGCTTGGCCC CATCAGCCAG AAGATGTACG CCATGCTGCC CTGTGGGGGC ATTGGGGTGG 2700 ACAGTGACAC GGTGTGGAAT GAGATGCACT CCTCAAGTGC CGTGCGAATG GCAGTGGGCT 2760 GCCTGGTGGA GCTGGCCTTC AAGGTGGCTG CAGGAGAGCT CAAGAATGGA TTTGCTATCA 2820 TCCGGCCCCC AGGACACCAT GCTGAGGAGT CCACAGCCAT GGGATTCTGC TTCTTCAACT 2880 CCGTAGCCAT CACAGCTAAA CTCCTGCAGC AGAAGCTGAG CGTGGGCAAG GTCCTCATCG 2940 TGGACTGGGA TATTCACCAT GGCAACGGCA CCCAGCAAGC ATTCTACAAC GATCCCTCTG 3000 TGCTCTACAT CTCCCTGCAT CGCTACGACA ACGGGAACTT CTTTCCAGGC TCTGGGGCTC 3060 CTGAAGAGGT TGGTGGAGGG CCAGGTGTGG GGTACAACGT AAATGTGGCG TGGACAGGAG 3120 GTGTGGATCC CCCCATTGGA GATGTGGAAT ACCTGACAGC CTTCAGGACA GTGGTGATGC 3180 CCATTGCCCA GGAGTTCTCA CCTGACGTCG TCCTAGTCTC CGCTGGGTTT GATGCTGTTG 3240 AAGGACATCT GTCTCCACTG GGTGGCTATT CTGTCACCGC CAGATGTTTT GGCCACTTGA 3300 CCAGGCAGCT CATGACACTG GCTGGGGGCC GGGTGGTGCT GGCCCTGGAG GGAGGCCATG 3360 ACTTGACCGC CATCTGTGAT GCCTCTGAGG CCTGTGTCTC GGCTCTGCTC AGCGTGGAGC 3420 TGCAGCCCTT GGATGAAGCA GTCTTGCAGC AAAAGCCCAG CGTCAATGCG GTTGCCACAC 3480 TAGAGAAAGT CATCGAGATC CAGAGCAAAC ACTGGAGCTG TGTACAGAGG TTTGCCGCTG 3540 GTCTGGGCTG CTCGCTGCGG GAGGCTCAGA CAGGTGAGAA AGAGGAGGCC GAGACTGTGA 3600 GCGCCATGGC CCTGCTTTCC GTGGGGGCTG AGCAGGCCCA GGCTGTTGCC ACTCAAGAGC 3660 ACAGCCCCAG GCCAGCAGAG GAGCCCATGG AGCAGGAGCC TGCCCTGTGA CACCCTGGCC 3720 CCCATCCCTC TGGGCTTCAT CATTGTGATT TTGTTTATTT TTTCTATTAA AAACAAAAAG 3780 TCACACAT
3789Nucleotide Fasta Sequence
>ENSMUSP00000102770.2|Class-I|Mus musculus GTGACGAGAGTGACGTCTCCGAATGTTGTTGTTGGTGGCGGCGGCGAGCGGAGCCGGAGGAGCCGCCGCAAAGATGGAGGAGCCGTCGAGGAGGCGCTGCCGCTGCTGTTGCCGCCGCTGCTGCCGCCGCCGCCCGCGAAGCCGGAGCTCGAGCCGCAGCGGGGATGCCGTTCTGAGTGCCTGACTGCCTCGCCCCGCCCCGAAGGATGGCCTTGGATGGGCATTAGAGGCACTGCGGCCCTGGGCTCGGGCTCCTGTCCCGTCCGTCTGTCTGTTATCGTCTGTCTCTCTTGACATCACAGCAGCTCCGCCCCCTCCCGTCCCAGCCCCCAACGTCAGCTTCCTGCAGGCCCAGAGCCGGCATGAACTCTCCCAACGAGTCGGCAGATGGCATGTCAGGCCGGGAACCATCCTTGGAAATCCTGCCACGGACTCCTCTGCACAGCATCCCTGTGGCAGTGGAGGTGAAGCCGGTGCTGCCAGGAGCCATGCCCAGCTCCATGGGGGGTGGAGGTGGAGGTAGCCCCAGCCCCGTGGAGCTTCGGGGGGCTCTGGCGGGCCCCATGGACCCTGCGCTACGGGAGCAGCAACTGCAGCAGGAGCTCCTGGTCCTCAAGCAGCAGCAGCAGCTCCAGAAGCAGCTCCTGTTCGCCGAGTTCCAGAAGCAGCACGACCACTTGACGCGGCAGCACGAGGTCCAGCTGCAGAAGCACCTCAAGCAGCAGCAGGAGATGCTGGCGGCTAAGAGGCAGCAGGAGCTGGAGCAGCAGCGGCAGCGGGAGCAGCAGCGGCAGGAGGAGCTGGAGAAACAGCGGCTGGAGCAGCAGCTGCTCATCCTGCGCAACAAGGAGAAGAGCAAAGAGAGTGCCATCGCCAGCACCGAGGTAAAGCTGAGGCTCCAGGAATTCCTGTTGTCCAAGTCAAAGGAGCCCACGCCAGGCGGCCTCAACCATTCCCTCCCACAGCACCCCAAATGCTGGGGAGCCCACCACGCTTCTTTGGACCAGAGTTCCCCTCCCCAGAGCGGCCCTCCTGGGACGCCTCCCTCCTACAAATTGCCTTTGCTTGGGCCCTATGACAGCCGTGATGACTTTCCCCTCCGTAAAACGGCCTCGGAACCCAACTTAAAAGTACGTTCGAGGCTAAAACAGAAGGTAGCCGAGAGGAGAAGCAGTCCCCTCCTGCGTCGAAAGGATGGCACTGTTATTAGTACTTTTAAGAAGAGAGCAGTTGAGATCACCGGCACGGGGCCTGGGGTGTCGTCCGTGTGTAACAGTGCGCCCGGCTCTGGCCCCAGCTCTCCCAACAGTTCCCACAGCACCATCGCTGAGAACGGCTTTACTGGCTCAGTCCCCAACATCCCCACTGAGATGATCCCCCAGCACCGGGCCCTCCCTCTGGACAGTTCCCCAAACCAGTTCAGCCTCTATACGTCTCCTTCTCTGCCCAACATCTCCCTAGGGCTGCAGGCCACTGTCACTGTCACCAACTCGCACCTCACCGCCTCCCCGAAGCTGTCAACACAGCAGGAGGCTGAGAGGCAGGCCCTTCAGTCCCTGCGGCAGGGCGGCACACTGACCGGCAAGTTCATGAGCACATCCTCCATCCCTGGCTGCCTGTTGGGAGTGGCACTGGAGGGTGACACAAGCCCCCACGGGCACGCTTCCCTGCTGCAGCACGTTTTGCTCCTGGAGCAGGCCCGGCAACAGAGCACGCTCATAGCAGTGCCGCTCCATGGGCAGTCCCCACTGGTGACGGGTGAACGTGTGGCCACCAGCATGAGGACGGTGGGTAAGCTCCCGAGGCACCGACCTCTGAGCCGCACTCAGTCCTCCCCGCTGCCGCAGAGTCCCCAGGCCCTGCAGCAGCTGGTCATGCAGCAGCAGCACCAGCAGTTCCTGGAGAAGCAGAAGCAGCAGCAGATGCAGCTGGGCAAGATCCTTACCAAAACTGGGGAGCTGTCAAGGCAGCCCACCACTCACCCGGAGGAGACAGAAGAGGAGCTGACGGAGCAGCAGGAGGCCTTGCTGGGAGAGGGGGCCCTGACCATTCCCCGGGAAGGCTCTACAGAAAGTGAGAGCACCCAGGAAGACCTAGAAGAGGAGGAGGAGGAGGAGGAGGAGGAAGAGGAGGACTGCATTCAGGTCAAGGATGAGGATGGCGAGAGTGGTCCTGATGAAGGCCCTGACTTAGAAGAGTCCAGTGCTGGTTACAAAAAGTTGTTCGCAGATGCCCAGCAGTTACAGCCCCTCCAGGTGTACCAGGCACCCCTCAGCCTGGCCACTGTGCCTCATCAGGCCCTGGGCCGCACCCAGTCCTCACCTGCTGCTCCTGGGAGCATGAAGAGCCCCACAGACCAACCCACTGTGGTGAAGCACCTCTTCACCACAGGTGTGGTCTATGACACGTTCATGCTGAAGCACCAGTGTATGTGCGGAAACACACACGTGCACCCAGAGCACGCCGGCCGCATCCAGAGCATCTGGTCCCGGCTGCAGGAAACTGGTCTGCTCGGCAAGTGTGAGCGGATCCGGGGTCGTAAAGCCACACTGGATGAAATCCAGACCGTGCACTCTGAGTACCACACCCTGCTCTATGGGACCAGCCCCCTTAACCGGCAGAAGCTGGACAGCAAGAAGCTGCTTGGCCCCATCAGCCAGAAGATGTACGCCATGCTGCCCTGTGGGGGCATTGGGGTGGACAGTGACACGGTGTGGAATGAGATGCACTCCTCAAGTGCCGTGCGAATGGCAGTGGGCTGCCTGGTGGAGCTGGCCTTCAAGGTGGCTGCAGGAGAGCTCAAGAATGGATTTGCTATCATCCGGCCCCCAGGACACCATGCTGAGGAGTCCACAGCCATGGGATTCTGCTTCTTCAACTCCGTAGCCATCACAGCTAAACTCCTGCAGCAGAAGCTGAGCGTGGGCAAGGTCCTCATCGTGGACTGGGATATTCACCATGGCAACGGCACCCAGCAAGCATTCTACAACGATCCCTCTGTGCTCTACATCTCCCTGCATCGCTACGACAACGGGAACTTCTTTCCAGGCTCTGGGGCTCCTGAAGAGGTTGGTGGAGGGCCAGGTGTGGGGTACAACGTAAATGTGGCGTGGACAGGAGGTGTGGATCCCCCCATTGGAGATGTGGAATACCTGACAGCCTTCAGGACAGTGGTGATGCCCATTGCCCAGGAGTTCTCACCTGACGTCGTCCTAGTCTCCGCTGGGTTTGATGCTGTTGAAGGACATCTGTCTCCACTGGGTGGCTATTCTGTCACCGCCAGATGTTTTGGCCACTTGACCAGGCAGCTCATGACACTGGCTGGGGGCCGGGTGGTGCTGGCCCTGGAGGGAGGCCATGACTTGACCGCCATCTGTGATGCCTCTGAGGCCTGTGTCTCGGCTCTGCTCAGCGTGGAGCTGCAGCCCTTGGATGAAGCAGTCTTGCAGCAAAAGCCCAGCGTCAATGCGGTTGCCACACTAGAGAAAGTCATCGAGATCCAGAGCAAACACTGGAGCTGTGTACAGAGGTTTGCCGCTGGTCTGGGCTGCTCGCTGCGGGAGGCTCAGACAGGTGAGAAAGAGGAGGCCGAGACTGTGAGCGCCATGGCCCTGCTTTCCGTGGGGGCTGAGCAGGCCCAGGCTGTTGCCACTCAAGAGCACAGCCCCAGGCCAGCAGAGGAGCCCATGGAGCAGGAGCCTGCCCTGTGACACCCTGGCCCCCATCCCTCTGGGCTTCATCATTGTGATTTTGTTTATTTTTTCTATTAAAAACAAAAAGTCACACAT
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Sequence Source |
Ensembl |
Keyword |
KW-0156--Chromatin regulator KW-0175--Coiled coil KW-0181--Complete proteome KW-0378--Hydrolase KW-0479--Metal-binding KW-1267--Proteomics identification KW-1185--Reference proteome KW-0678--Repressor KW-0804--Transcription KW-0805--Transcription regulation KW-0862--Zinc --
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Interpro |
IPR000286--His_deacetylse IPR023801--His_deacetylse_dom IPR024643--Hist_deacetylase_Gln_rich_N IPR017320--Histone_deAcase_II_euk IPR030703--Histone_deacetylase_5
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PROSITE |
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Pfam |
PF12203--HDAC4_Gln PF00850--Hist_deacetyl
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Gene Ontology |
GO:0005737--C:cytoplasm GO:0000118--C:histone deacetylase complex GO:0046872--F:metal ion binding GO:0032041--F:NAD-dependent histone deacetylase activity (H3-K14 specific) GO:0040029--P:regulation of gene expression, epigenetic GO:0006355--P:regulation of transcription, DNA-templated GO:0006351--P:transcription, DNA-templated
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Orthology |
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Created Date |
25-Jun-2016 |