| Tag |
Content |
| WERAM ID |
WERAM-Art-0132 |
| Ensembl Protein ID |
AT5G35600.1 |
| Uniprot Accession |
Q9FH09; HDA7_ARATH; A0MFJ3
|
| Genbank Protein ID |
NP_198410.1
|
| Protein Name |
Histone deacetylase 7 |
| Genbank Nucleotide ID |
NM_122951.1
|
| Gene Name |
HDA7;At5g35600;K2K18.5 |
| Ensembl Information |
|
| Details |
| Type |
Family |
Domain |
Substrates |
AA |
References (PMIDs) |
| HDAC |
Class-I |
Histone deacetylase |
H2A; H2B; H3; H4 |
K |
26689639
|
|
| Status |
Reviewed |
| Classification |
| Type |
Family |
E-value |
Score |
Start |
End |
| HDAC |
Class-I |
1.20e-141 |
472.6 |
10 |
323 |
|
| Organism |
Arabidopsis thaliana |
| NCBI Taxa ID |
3702 |
Functional Description
(View)Functional Description
Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. May be involved in flowering induction. Histone deacetylases act via the formation of large multiprotein complexes (By similarity). |
Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. May be involved in flowering induction. Histone deacetylases act via the formation of large multiprotein complexes (By similarity).
|
| Domain Profile |
HDAC Class-I
class-1.txt 1 kkvayaydedvgeyhygqkhpmkpkrlsltheLvlnyglskkleivkpkkasaeellkfhseeyieflkkvepenae....elskelkkfnvge..dc 92
++v+y+y++++g+y+yg+++p+kp+r+++th+L+l+y+l++++ei +p+ a+a+++ kfhs eyi+flk+v+pe+ + ++s++lk+fnv+ d
AT5G35600.1 10 RRVSYFYEPMIGDYYYGVNQPTKPQRIRVTHNLILSYNLHRHMEINHPDLADASDFEKFHSLEYINFLKSVTPETVTdphpSVSENLKRFNVDVdwDG 107
589************************************************************************9977777789******9874589 PP
class-1.txt 93 PvfdglfeycqlitGasleaakkLnkkeadiainwaGGlhhakkseasGfcyvnDivlailellkkhkrvlyididlhhGDgveeafyttdrvmtvsf 190
Pvf++lf+yc++++G+s++aa+kLn++eadiainwaGG+hh+kk++asGf yvnD+vlailellk++krvlyi+i + hGD+veeaf+ tdrvmtvsf
AT5G35600.1 108 PVFHNLFDYCRAYAGGSISAAAKLNRQEADIAINWAGGMHHVKKDKASGFGYVNDVVLAILELLKSFKRVLYIEIGFPHGDEVEEAFKDTDRVMTVSF 205
************************************************************************************************** PP
class-1.txt 191 hkygeeffPgtGdlsdvgaekgkyyavnvPlkdgidDesyekifksviskvieafePeavvlqcGaDslagDrlgefnlsikghaecvkfvksfnlpl 288
hk g+ tGd+sd+g++kg+yy++n Plkdg+dD s++ +f +vi++ +e++ePe++vlqcGaDslagD++g+fnlsikgh++c+++v+sfn+pl
AT5G35600.1 206 HKVGD-----TGDISDYGEGKGQYYSLNAPLKDGLDDFSLRGLFIPVIHRAMEIYEPEVIVLQCGADSLAGDPFGTFNLSIKGHGDCLQYVRSFNVPL 298
*****.....**************************************************************************************** PP
class-1.txt 289 lvlGGGGYtlrnvaRcwtyetavvl 313
++lGGGGYtl nvaRcw+yeta+++
AT5G35600.1 299 MILGGGGYTLPNVARCWCYETAIAV 323
**********************986 PP
|
Protein Sequence
(Fasta) | MASLADGGKR RVSYFYEPMI GDYYYGVNQP TKPQRIRVTH NLILSYNLHR HMEINHPDLA 60
DASDFEKFHS LEYINFLKSV TPETVTDPHP SVSENLKRFN VDVDWDGPVF HNLFDYCRAY 120
AGGSISAAAK LNRQEADIAI NWAGGMHHVK KDKASGFGYV NDVVLAILEL LKSFKRVLYI 180
EIGFPHGDEV EEAFKDTDRV MTVSFHKVGD TGDISDYGEG KGQYYSLNAP LKDGLDDFSL 240
RGLFIPVIHR AMEIYEPEVI VLQCGADSLA GDPFGTFNLS IKGHGDCLQY VRSFNVPLMI 300
LGGGGYTLPN VARCWCYETA IAVGEQLDND LPGNDYMKYF RPDYKLHILP TNRQNLNTRL 360
DIITMRETLL AQLSLVMHAP SVPFQDTPSS SQATEAAEVD MEKRNDPRI 409Protein Fasta Sequence
>AT5G35600.1|HDA7;At5g35600;K2K18.5|Arabidopsis thaliana
MASLADGGKRRVSYFYEPMIGDYYYGVNQPTKPQRIRVTHNLILSYNLHRHMEINHPDLADASDFEKFHSLEYINFLKSVTPETVTDPHPSVSENLKRFNVDVDWDGPVFHNLFDYCRAYAGGSISAAAKLNRQEADIAINWAGGMHHVKKDKASGFGYVNDVVLAILELLKSFKRVLYIEIGFPHGDEVEEAFKDTDRVMTVSFHKVGDTGDISDYGEGKGQYYSLNAPLKDGLDDFSLRGLFIPVIHRAMEIYEPEVIVLQCGADSLAGDPFGTFNLSIKGHGDCLQYVRSFNVPLMILGGGGYTLPNVARCWCYETAIAVGEQLDNDLPGNDYMKYFRPDYKLHILPTNRQNLNTRLDIITMRETLLAQLSLVMHAPSVPFQDTPSSSQATEAAEVDMEKRNDPRI |
Nucleotide Sequence
(Fasta) | ATGGCGAGCT TAGCCGACGG AGGAAAACGC CGCGTCAGTT ACTTCTACGA GCCAATGATC 60
GGCGACTACT ACTACGGCGT TAACCAGCCA ACGAAACCTC AACGAATCCG TGTCACTCAC 120
AACCTCATCC TCAGCTATAA CCTCCACCGC CACATGGAAA TCAACCACCC AGACCTCGCC 180
GATGCTTCCG ATTTCGAAAA ATTCCACTCG CTGGAGTATA TCAACTTCCT CAAATCCGTC 240
ACGCCGGAAA CCGTAACCGA TCCTCATCCT TCCGTCTCTG AAAACCTCAA GCGCTTCAAC 300
GTAGATGTGG ATTGGGACGG TCCTGTCTTC CATAACCTCT TCGATTATTG TCGTGCTTAC 360
GCTGGTGGTT CTATTAGCGC CGCCGCGAAA TTGAACCGTC AAGAAGCCGA TATTGCCATA 420
AACTGGGCCG GTGGTATGCA CCATGTGAAG AAAGATAAAG CTTCTGGCTT TGGTTATGTC 480
AATGACGTTG TGCTTGCGAT TCTCGAGTTA CTAAAATCTT TCAAGAGAGT TCTCTACATA 540
GAAATTGGTT TTCCTCATGG TGATGAAGTG GAAGAAGCAT TTAAGGATAC TGATAGAGTA 600
ATGACTGTTT CTTTCCACAA AGTTGGGGAC ACCGGAGACA TAAGTGACTA TGGGGAAGGG 660
AAAGGACAAT ACTATTCACT CAATGCACCA TTAAAGGATG GTTTGGATGA TTTTAGTCTT 720
CGTGGTTTGT TCATTCCTGT TATCCACAGA GCTATGGAAA TCTATGAGCC AGAAGTAATT 780
GTTCTTCAGT GTGGTGCTGA TTCTTTAGCT GGTGATCCGT TTGGTACATT CAACTTGTCT 840
ATCAAGGGTC ATGGTGATTG CTTACAGTAC GTAAGATCTT TTAATGTTCC TCTCATGATC 900
TTGGGGGGTG GAGGTTATAC TCTTCCAAAT GTTGCTCGTT GCTGGTGCTA TGAGACGGCG 960
ATTGCGGTTG GAGAACAACT TGACAATGAT CTCCCAGGCA ATGATTACAT GAAGTATTTT 1020
CGTCCAGATT ACAAGCTTCA TATATTGCCA ACCAACAGGC AGAATTTAAA CACACGATTA 1080
GATATTATAA CAATGAGGGA AACTTTACTA GCGCAACTTT CTCTAGTAAT GCACGCACCT 1140
AGTGTACCGT TTCAAGACAC TCCATCAAGC AGTCAAGCCA CTGAAGCGGC GGAAGTGGAC 1200
ATGGAGAAGA GAAATGATCC ACGCATTTGA
1231Nucleotide Fasta Sequence
>AT5G35600.1|Class-I|Arabidopsis thaliana
ATGGCGAGCTTAGCCGACGGAGGAAAACGCCGCGTCAGTTACTTCTACGAGCCAATGATCGGCGACTACTACTACGGCGTTAACCAGCCAACGAAACCTCAACGAATCCGTGTCACTCACAACCTCATCCTCAGCTATAACCTCCACCGCCACATGGAAATCAACCACCCAGACCTCGCCGATGCTTCCGATTTCGAAAAATTCCACTCGCTGGAGTATATCAACTTCCTCAAATCCGTCACGCCGGAAACCGTAACCGATCCTCATCCTTCCGTCTCTGAAAACCTCAAGCGCTTCAACGTAGATGTGGATTGGGACGGTCCTGTCTTCCATAACCTCTTCGATTATTGTCGTGCTTACGCTGGTGGTTCTATTAGCGCCGCCGCGAAATTGAACCGTCAAGAAGCCGATATTGCCATAAACTGGGCCGGTGGTATGCACCATGTGAAGAAAGATAAAGCTTCTGGCTTTGGTTATGTCAATGACGTTGTGCTTGCGATTCTCGAGTTACTAAAATCTTTCAAGAGAGTTCTCTACATAGAAATTGGTTTTCCTCATGGTGATGAAGTGGAAGAAGCATTTAAGGATACTGATAGAGTAATGACTGTTTCTTTCCACAAAGTTGGGGACACCGGAGACATAAGTGACTATGGGGAAGGGAAAGGACAATACTATTCACTCAATGCACCATTAAAGGATGGTTTGGATGATTTTAGTCTTCGTGGTTTGTTCATTCCTGTTATCCACAGAGCTATGGAAATCTATGAGCCAGAAGTAATTGTTCTTCAGTGTGGTGCTGATTCTTTAGCTGGTGATCCGTTTGGTACATTCAACTTGTCTATCAAGGGTCATGGTGATTGCTTACAGTACGTAAGATCTTTTAATGTTCCTCTCATGATCTTGGGGGGTGGAGGTTATACTCTTCCAAATGTTGCTCGTTGCTGGTGCTATGAGACGGCGATTGCGGTTGGAGAACAACTTGACAATGATCTCCCAGGCAATGATTACATGAAGTATTTTCGTCCAGATTACAAGCTTCATATATTGCCAACCAACAGGCAGAATTTAAACACACGATTAGATATTATAACAATGAGGGAAACTTTACTAGCGCAACTTTCTCTAGTAATGCACGCACCTAGTGTACCGTTTCAAGACACTCCATCAAGCAGTCAAGCCACTGAAGCGGCGGAAGTGGACATGGAGAAGAGAAATGATCCACGCATTTGA
|
| Sequence Source |
Ensembl |
| Keyword |
KW-0156--Chromatin regulator
KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0678--Repressor
KW-0804--Transcription
KW-0805--Transcription regulation
--
|
| Interpro |
IPR000286--His_deacetylse
IPR003084--His_deacetylse_1
IPR023801--His_deacetylse_dom
|
| PROSITE |
|
| Pfam |
PF00850--Hist_deacetyl
|
| Gene Ontology |
GO:0005634--C:nucleus
GO:0032041--F:NAD-dependent histone deacetylase activity (H3-K14 specific)
GO:0009793--P:embryo development ending in seed dormancy
GO:0009553--P:embryo sac development
GO:0006355--P:regulation of transcription, DNA-templated
GO:0009845--P:seed germination
GO:0006351--P:transcription, DNA-templated
|
| Orthology |
|
| Created Date |
25-Jun-2016 |
