WERAM Information

Tag Content
WERAM ID WERAM-Art-0080
Ensembl Protein ID AT3G44490.1
Uniprot Accession Q9LXN8; HDA17_ARATH
Genbank Protein ID NP_190035.1
Protein Name Histone deacetylase 17
Genbank Nucleotide ID NM_114317.2
Gene Name HDA17;At3g44490;F14L2.40
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
AT3G44490 AT3G44490.1 AT3G44490.1
Details
Type Family Domain Substrates AA References (PMIDs)
HDAC Class-I Histone deacetylase H2A; H2B; H3; H4 K 26508133
Status Reviewed
Classification
Type Family E-value Score Start End
HDAC Class-I 2.40e-18 67.6 2 49
Organism Arabidopsis thaliana
NCBI Taxa ID 3702
Functional Description
(View)		 Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes (By similarity).
Domain Profile
  HDAC Class-I
  class-1.txt 266 efnlsikghaecvkfvksfnlpllvlGGGGYtlrnvaRcwtyetavvl 313
                   f++ ++ghaecvkfvk+fnlpllv GGGGYt++nvaRcwt+et+++l
  AT3G44490.1   2 AFSMLFTGHAECVKFVKKFNLPLLVTGGGGYTKENVARCWTVETGILL 49 
                  5999******************************************97 PP
Protein Sequence
(Fasta)		MAFSMLFTGH AECVKFVKKF NLPLLVTGGG GYTKENVARC WTVETGILLD TELPNEISEN 60
DYIKYFAPDF SLKIPGGHIE NLNTKSYISS IKVQILENLR YIQHAPSVQM QEVPPDFYIP 120
DFDEDEQNPD VRVDQRSRDK QIQRDDEYFD GDNDNDAS 158
Nucleotide Sequence
(Fasta)		ATGGCTTTCT CTATGCTTTT CACAGGACAT GCTGAATGTG TTAAATTCGT GAAGAAGTTC 60
AATCTTCCCT TACTGGTTAC AGGAGGTGGA GGATACACAA AGGAGAATGT AGCTCGTTGT 120
TGGACCGTTG AGACTGGCAT TCTTTTGGAT ACAGAACTTC CTAATGAGAT TTCTGAAAAC 180
GACTACATAA AGTATTTTGC GCCGGATTTT TCTTTGAAGA TACCGGGTGG TCACATTGAG 240
AATCTTAATA CCAAATCATA CATCAGTTCC ATCAAAGTGC AGATTTTGGA GAATTTGCGA 300
TACATTCAAC ACGCTCCAAG CGTACAGATG CAGGAGGTTC CACCGGATTT CTACATACCG 360
GATTTTGATG AAGACGAACA AAATCCGGAT GTACGTGTGG ATCAGCGTTC ACGGGATAAG 420
CAGATCCAGA GGGATGATGA ATATTTCGAT GGAGACAACG ATAACGATGC ATCGTAAAAC 480
ATCGATTCTT AGAAATTGTT GGTTAATTTT TTTTGTTTAG TTATGAGATT TGTAATGATA 540
TCAACACTTT AACGGCTATG GGGCACCAAA ACCACTTCTG ATTGATTCCA TCTTCTTCAT 600
GTTTTCGTCT TGGTGTATAT GAATGAAGCT TTTTGGTTCA CTTTCTCATC ATTGTGACTT 660
ATATAGTGAT CAAATTCGTT ACATATTGTA 691
Sequence Source Ensembl
Keyword

KW-0156--Chromatin regulator
KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0678--Repressor
KW-0804--Transcription
KW-0805--Transcription regulation
--
Interpro

IPR000286--His_deacetylse
IPR023801--His_deacetylse_dom
PROSITE
Pfam
Gene Ontology

GO:0005634--C:nucleus
GO:0032041--F:NAD-dependent histone deacetylase activity (H3-K14 specific)
GO:0006355--P:regulation of transcription, DNA-templated
GO:0006351--P:transcription, DNA-templated
Orthology
WERAM ID Ensembl Protein ID Species Identity E-value Score
WERAM-Arl-0024 fgenesh1_pg.C_scaffold_5000937 Arabidopsis lyrata 97 2e-79 291
WERAM-Bro-0059 Bo3g120880.1 Brassica oleracea 90 1e-74 275
WERAM-Brr-0098 Bra019424.1-P Brassica rapa 90 1e-74 275
WERAM-Viv-0093 VIT_15s0021g00610.t01 Vitis vinifera 84 1e-70 261
WERAM-Prp-0063 EMJ06433 Prunus persica 82 4e-69 256
WERAM-Sol-0138 Solyc11g067020.1.1 Solanum lycopersicum 80 5e-69 256
WERAM-Pot-0020 POPTR_0001s46430.1 Populus trichocarpa 82 9e-69 256
WERAM-Glm-0130 GLYMA11G19290.1 Glycine max 82 1e-68 255
WERAM-Mua-0089 GSMUA_Achr6P17260_001 Musa acuminata 80 3e-67 250
WERAM-Thc-0114 EOY33523 Theobroma cacao 80 8e-67 249
WERAM-Met-0097 AES88434 Medicago truncatula 80 8e-67 249
WERAM-Zem-0071 GRMZM2G119703_P01 Zea mays 76 2e-64 241
WERAM-Amt-0048 ERN13133 Amborella trichopoda 78 3e-64 241
WERAM-Orbr-0052 OB04G18820.1 Oryza brachyantha 76 1e-63 238
WERAM-Sei-0035 Si010167m Setaria italica 76 2e-63 238
WERAM-Sob-0086 Sb06g015420.1 Sorghum bicolor 75 2e-63 238
WERAM-Orl-0026 KN538765.1_FGP002 Oryza longistaminata 75 6e-63 236
WERAM-Orm-0045 OMERI04G10320.1 Oryza meridionalis 75 6e-63 236
WERAM-Orni-0039 ONIVA04G09660.1 Oryza nivara 75 8e-63 236
WERAM-Ori-0051 BGIOSGA016344-PA Oryza indica 75 8e-63 236
WERAM-Orgl-0043 OGLUM04G11380.3 Oryza glumaepatula 75 8e-63 236
WERAM-Org-0044 ORGLA04G0087200.1 Oryza glaberrima 75 8e-63 236
WERAM-Orr-0042 ORUFI04G12890.1 Oryza rufipogon 75 9e-63 236
WERAM-Tra-0081 Traes_2DL_625707569.1 Triticum aestivum 72 1e-62 235
WERAM-Brd-0123 BRADI5G09190.1 Brachypodium distachyon 73 2e-62 234
WERAM-Orb-0042 OBART04G11700.1 Oryza barthii 74 3e-62 234
WERAM-Aet-0101 EMT12816 Aegilops tauschii 72 3e-62 234
WERAM-Php-0035 PP1S180_68V6.1 Physcomitrella patens 72 6e-60 226
WERAM-Sem-0137 EFJ33452 Selaginella moellendorffii 70 2e-58 221
WERAM-Tru-0028 TRIUR3_16261-P1 Triticum urartu 73 2e-58 221
WERAM-Orp-0042 OPUNC04G09700.1 Oryza punctata 74 2e-57 218
WERAM-Sot-0082 PGSC0003DMT400068240 Solanum tuberosum 62 4e-47 184
WERAM-Chr-0011 EDP01149 Chlamydomonas reinhardtii 47 2e-38 155
WERAM-Myl-0215 ENSMLUP00000016605.1 Myotis lucifugus 51 3e-38 154
WERAM-Tut-0167 ENSTTRP00000014262.1 Tursiops truncatus 52 8e-38 153
WERAM-Chh-0084 ENSCHOP00000009394.1 Choloepus hoffmanni 51 6e-37 150
WERAM-Ere-0018 ENSEEUP00000001196.1 Erinaceus europaeus 57 6e-37 150
WERAM-Pes-0020 ENSPSIP00000004435.1 Pelodiscus sinensis 54 8e-37 149
WERAM-Nol-0026 ENSNLEP00000003167.1 Nomascus leucogenys 57 9e-37 149
WERAM-Mam-0083 ENSMMUP00000013015.2 Macaca mulatta 57 9e-37 149
WERAM-Cap-0092 ENSCPOP00000006985.2 Cavia porcellus 57 9e-37 149
WERAM-Orc-0030 ENSOCUP00000003186.2 Oryctolagus cuniculus 57 9e-37 149
WERAM-Poa-0013 ENSPPYP00000001838.2 Pongo abelii 57 9e-37 149
WERAM-Ova-0221 ENSOARP00000022517.1 Ovis aries 57 9e-37 149
WERAM-Otg-0072 ENSOGAP00000005101.2 Otolemur garnettii 57 9e-37 149
WERAM-Hos-0092 ENSP00000362649.3 Homo sapiens 57 9e-37 149
WERAM-Gog-0132 ENSGGOP00000011454.2 Gorilla gorilla 57 9e-37 149
WERAM-Bot-0118 ENSBTAP00000016877.5 Bos taurus 57 9e-37 149
WERAM-Pat-0210 ENSPTRP00000060659.1 Pan troglodytes 57 9e-37 149
WERAM-Ptv-0152 ENSPVAP00000012567.1 Pteropus vampyrus 57 9e-37 149
WERAM-Ocp-0006 ENSOPRP00000000780.1 Ochotona princeps 57 9e-37 149
WERAM-Chs-0011 ENSCSAP00000016960.1 Chlorocebus sabaeus 57 1e-36 149
WERAM-Ran-0062 ENSRNOP00000012854.5 Rattus norvegicus 57 1e-36 149
WERAM-Mum-0209 ENSMUSP00000078339.4 Mus musculus 57 1e-36 149
WERAM-Ora-0012 ENSOANP00000001904.1 Ornithorhynchus anatinus 57 1e-36 149
WERAM-Caj-0006 ENSCJAP00000001664.2 Callithrix jacchus 57 1e-36 149
WERAM-Fia-0005 ENSFALP00000000658.1 Ficedula albicollis 57 1e-36 149
WERAM-Sus-0201 ENSSSCP00000023024.1 Sus scrofa 57 1e-36 149
WERAM-Gaga-0034 ENSGALP00000005212.3 Gallus gallus 57 1e-36 149
WERAM-Paa-0048 ENSPANP00000004176.1 Papio anubis 57 1e-36 149
WERAM-Tag-0022 ENSTGUP00000001473.1 Taeniopygia guttata 57 1e-36 149
WERAM-Anp-0136 ENSAPLP00000014652.1 Anas platyrhynchos 57 1e-36 149
WERAM-Eqc-0125 ENSECAP00000014039.1 Equus caballus 57 1e-36 149
WERAM-Mod-0160 ENSMODP00000021783.2 Monodelphis domestica 57 2e-36 149
WERAM-Fec-0127 ENSFCAP00000011581.3 Felis catus 57 2e-36 149
WERAM-Meg-0047 ENSMGAP00000004521.2 Meleagris gallopavo 57 2e-36 149
WERAM-Mim-0092 ENSMICP00000008598.1 Microcebus murinus 57 2e-36 148
WERAM-Mup-0173 ENSMPUP00000015122.1 Mustela putorius furo 57 2e-36 148
WERAM-Dan-0175 ENSDNOP00000033349.1 Dasypus novemcinctus 57 2e-36 148
WERAM-Anc-0033 ENSACAP00000004062.3 Anolis carolinensis 53 6e-36 147
WERAM-Cii-0014 ENSCINP00000005410.3 Ciona intestinalis 48 9e-36 146
WERAM-Caf-0116 ENSCAFP00000015619.3 Canis familiaris 59 1e-35 145
WERAM-Aim-0087 ENSAMEP00000008076.1 Ailuropoda melanoleuca 59 1e-35 145
WERAM-Scs-0023 EDO03342 Sclerotinia sclerotiorum 47 2e-35 145
WERAM-Prc-0059 ENSPCAP00000005589.1 Procavia capensis 54 3e-35 144
WERAM-Pof-0067 ENSPFOP00000005770.2 Poecilia formosa 54 5e-35 143
WERAM-Loa-0056 ENSLAFP00000004079.2 Loxodonta africana 53 6e-35 143
WERAM-Trr-0017 EGR48353 Trichoderma reesei 45 8e-35 143
WERAM-Orla-0197 ENSORLP00000022529.1 Oryzias latipes 52 1e-34 142
WERAM-Trv-0003 EHK19072 Trichoderma virens 46 2e-34 142
WERAM-Asni-0020 CADANGAP00005938 Aspergillus niger 46 2e-34 141
WERAM-Chg-0005 EAQ93036 Chaetomium globosum 44 2e-34 141
WERAM-Coi-0024 EAS33504 Coccidioides immitis 44 3e-34 141
WERAM-Gaa-0093 ENSGACP00000012045.1 Gasterosteus aculeatus 53 3e-34 141
WERAM-Xim-0002 ENSXMAP00000000390.1 Xiphophorus maculatus 52 4e-34 140
WERAM-Ten-0109 ENSTNIP00000012136.1 Tetraodon nigroviridis 53 4e-34 140
WERAM-Orn-0087 ENSONIP00000009730.1 Oreochromis niloticus 52 5e-34 140
WERAM-Asfu-0015 CADAFUAP00003503 Aspergillus fumigatus 46 5e-34 140
WERAM-Gag-0026 GGTG_08607T0 Gaeumannomyces graminis 44 5e-34 140
WERAM-Map-0015 MAPG_05105T0 Magnaporthe poae 44 5e-34 140
WERAM-Pem-0092 ENSPMAP00000009670.1 Petromyzon marinus 52 6e-34 140
WERAM-Asf-0020 CADAFLAP00008921 Aspergillus flavus 45 7e-34 140
WERAM-Asc-0037 CADACLAP00008612 Aspergillus clavatus 46 7e-34 140
WERAM-Asn-0024 CADANIAP00005952 Aspergillus nidulans 44 9e-34 139
WERAM-Ast-0010 CADATEAP00004306 Aspergillus terreus 46 1e-33 139
WERAM-Gam-0033 ENSGMOP00000003469.1 Gadus morhua 52 1e-33 139
WERAM-Tar-0126 ENSTRUP00000027023.1 Takifugu rubripes 52 2e-33 138
WERAM-Scj-0003 EEB05565 Schizosaccharomyces japonicus 44 3e-33 138
WERAM-Leo-0176 ENSLOCP00000020984.1 Lepisosteus oculatus 51 3e-33 137
WERAM-Dar-0035 ENSDARP00000051798.4 Danio rerio 50 3e-33 137
WERAM-Tum-0029 CAZ85499 Tuber melanosporum 44 4e-33 137
WERAM-Drm-0018 FBpp0073173 Drosophila melanogaster 51 4e-33 137
WERAM-Tas-0085 ENSTSYP00000008588.1 Tarsius syrichta 53 5e-33 137
WERAM-Ict-0111 ENSSTOP00000011457.2 Ictidomys tridecemlineatus 53 5e-33 137
WERAM-Ect-0064 ENSETEP00000006883.1 Echinops telfairi 53 5e-33 137
WERAM-Dio-0132 ENSDORP00000012520.1 Dipodomys ordii 53 5e-33 137
WERAM-Sah-0134 ENSSHAP00000014467.1 Sarcophilus harrisii 53 5e-33 137
WERAM-Usm-0008 UM01352P0 Ustilago maydis 42 1e-32 135
WERAM-Mao-0017 MGG_05857T0 Magnaporthe oryzae 42 1e-32 135
WERAM-Xet-0050 ENSXETP00000015978.3 Xenopus tropicalis 52 2e-32 135
WERAM-Lep-0023 LPERR02G07360.1 Leersia perrieri 51 2e-32 135
WERAM-Ved-0020 EGY15146 Verticillium dahliae 43 3e-32 134
WERAM-Ors-0059 OS06T0583400-01 Oryza sativa 48 8e-32 133
WERAM-Scp-0033 SPBC36.05c.1:pep Schizosaccharomyces pombe 44 1e-31 132
WERAM-Hov-0001 MLOC_10109.1 Hordeum vulgare 47 2e-31 132
WERAM-Asm-0125 ENSAMXP00000012478.1 Astyanax mexicanus 47 2e-31 131
WERAM-Lac-0087 ENSLACP00000011092.1 Latimeria chalumnae 45 2e-31 131
WERAM-Cae-0007 R06C1.1.2 Caenorhabditis elegans 45 2e-31 131
WERAM-Cis-0077 ENSCSAVP00000016740.1 Ciona savignyi 43 3e-31 131
WERAM-Spr-0005 CBQ70764 Sporisorium reilianum 42 8e-31 129
Created Date 25-Jun-2016