| Tag |
Content |
| WERAM ID |
WERAM-Ran-0042 |
| Ensembl Protein ID |
ENSRNOP00000008962.5 |
| Uniprot Accession |
B2GUW3; B2GUW3_RAT
|
| Genbank Protein ID |
NP_001100080.2
|
| Protein Name |
Hdac11 protein |
| Genbank Nucleotide ID |
NM_001106610.2
|
| Gene Name |
HDAC11;Hdac11_predicted;rCG_56042 |
| Ensembl Information |
|
| Details |
| Type |
Family |
Domain |
Substrates |
AA |
References (PMIDs) |
| HDAC |
Class-IV |
Hist_deacetyl |
H2A; H2B; H3; H4 |
K |
26395029; 26365275
|
|
| Status |
Reviewed |
| Classification |
| Type |
Family |
E-value |
Score |
Start |
End |
| HDAC |
Class-IV |
9.10e-170 |
564 |
31 |
317 |
| HDAC |
Class-I |
9.60e-26 |
91.6 |
29 |
309 |
|
| Organism |
Rattus norvegicus |
| NCBI Taxa ID |
10116 |
Functional Description
(View) |
|
| Domain Profile |
HDAC Class-IV
class-4.txt 1 leklhpfdaskwkkvikflkeeklledealveareaskedllvvhtrkylkslksslkvatiteiplvaflpnflvqrkvlrplrlqag 89
leklhpfda+kw+kvi+flkeekll+d++lveareas+edllvvhtr+yl++lk+s++vatiteip+v+flpnflvqrkvlrplr+q+g
ENSRNOP00000008962.5 31 LEKLHPFDAGKWGKVINFLKEEKLLSDGMLVEAREASEEDLLVVHTRRYLNELKWSFVVATITEIPPVIFLPNFLVQRKVLRPLRTQTG 119
79*************************************************************************************** PP
class-4.txt 90 GtilaaklaverGwainvGGGfhhcsserGGGfcayaditlaikflferlkaisrviiidldahqGnGherdfaddkrvyildvynrei 178
Gti+a+klaverGwainvGGGfhhcss+rGGGfcayaditlaikflfer+++isr++iidldahqGnGherdf++dkrvyi+dvynr+i
ENSRNOP00000008962.5 120 GTIMAGKLAVERGWAINVGGGFHHCSSDRGGGFCAYADITLAIKFLFERVEGISRATIIDLDAHQGNGHERDFMGDKRVYIMDVYNRHI 208
***************************************************************************************** PP
class-4.txt 179 ypkdrvakeairrkvelesgtedeeylekleralkkslqefepdlvvynaGtdvleGdrlGalkispegivkrdevvfrlvrakdipiv 267
yp+dr+akeairrkvele+gtedeeylek+er++++slqe+ pd+vvynaGtdvleGdrlG+l+isp+givkrdevvfr+vra+dipi+
ENSRNOP00000008962.5 209 YPGDRFAKEAIRRKVELEWGTEDEEYLEKVERNVRRSLQEHLPDVVVYNAGTDVLEGDRLGGLSISPAGIVKRDEVVFRVVRAHDIPIL 297
***************************************************************************************** PP
class-4.txt 268 mvtsGGyqkrsarviadsil 287
mvtsGGyqkr+ar+iadsil
ENSRNOP00000008962.5 298 MVTSGGYQKRTARIIADSIL 317
******************95 PP
HDAC Class-I
class-1.txt 14 yhygqkhpmkpkrlsltheLvlnyglskkleivkpkkasaeellkfhseeyieflkkve.penaeelskelkkfnvgedcPvfdglfey 101
+ ++ hp ++ + +++ + +l + +v++++as e+ll +h+ y++ lk + + + +e++ + + v ++
ENSRNOP00000008962.5 29 MGLEKLHPFDAGKWGKVINFLKEEKLLSDGMLVEAREASEEDLLVVHTRRYLNELKWSFvVATITEIPPVIFL----PNFLVQRKVLRP 113
5556778888888888888888888888888999999999999999999999999865404455555543333....334455566666 PP
class-1.txt 102 cqlitGasleaakkLnkkeadiainwaGGlhhakkseasGfcyvnDivlailellk...khkrvlyididlhhGDgveeafyttdrvmt 187
++ tG+++ a kL e+ ain GG+hh ++ Gfc Di lai l +r + id+d h G+g e f +rv
ENSRNOP00000008962.5 114 LRTQTGGTIMAG-KLA-VERGWAINVGGGFHHCSSDRGGGFCAYADITLAIKFLFErveGISRATIIDLDAHQGNGHERDFMGDKRVYI 200
7899****9876.554.45788*****************************99987222467999**********************98 PP
class-1.txt 188 vsfhkygeeffPgtGdlsdvgaekgkyyavnvPlkdgidDesyekifksviskvieafePeavvlqcGaDslagDrlgefnlsikghae 276
+ + y+ + +Pg ++ v l+ g +De+y + +++ +++ ++ + P++vv + G+D l gDrlg ++s g+ +
ENSRNOP00000008962.5 201 MDV--YNRHIYPGDRFAKEAIRR-------KVELEWGTEDEEYLEKVERNVRRSLQEHLPDVVVYNAGTDVLEGDRLGGLSISPAGIVK 280
766..88889**97655554443.......479************99*99***********************************9976 PP
class-1.txt 277 ....cvkfvksfnlpllvlGGGGYtlrnva 302
+ ++v+ +++p+l++ GGY++r a
ENSRNOP00000008962.5 281 rdevVFRVVRAHDIPILMVTSGGYQKRT-A 309
56656799****************9874.4 PP
|
Protein Sequence
(Fasta) | MPHATQLYQH VPEKRWPIVY SPRYNITFMG LEKLHPFDAG KWGKVINFLK EEKLLSDGML 60
VEAREASEED LLVVHTRRYL NELKWSFVVA TITEIPPVIF LPNFLVQRKV LRPLRTQTGG 120
TIMAGKLAVE RGWAINVGGG FHHCSSDRGG GFCAYADITL AIKFLFERVE GISRATIIDL 180
DAHQGNGHER DFMGDKRVYI MDVYNRHIYP GDRFAKEAIR RKVELEWGTE DEEYLEKVER 240
NVRRSLQEHL PDVVVYNAGT DVLEGDRLGG LSISPAGIVK RDEVVFRVVR AHDIPILMVT 300
SGGYQKRTAR IIADSILNLH DLGLIGPEFP YVPARNSSIP LLSRAVP 347Protein Fasta Sequence
>ENSRNOP00000008962.5|HDAC11;Hdac11_predicted;rCG_56042|Rattus norvegicus
MPHATQLYQHVPEKRWPIVYSPRYNITFMGLEKLHPFDAGKWGKVINFLKEEKLLSDGMLVEAREASEEDLLVVHTRRYLNELKWSFVVATITEIPPVIFLPNFLVQRKVLRPLRTQTGGTIMAGKLAVERGWAINVGGGFHHCSSDRGGGFCAYADITLAIKFLFERVEGISRATIIDLDAHQGNGHERDFMGDKRVYIMDVYNRHIYPGDRFAKEAIRRKVELEWGTEDEEYLEKVERNVRRSLQEHLPDVVVYNAGTDVLEGDRLGGLSISPAGIVKRDEVVFRVVRAHDIPILMVTSGGYQKRTARIIADSILNLHDLGLIGPEFPYVPARNSSIPLLSRAVP |
Nucleotide Sequence
(Fasta) | CTCCCCGCTA CACCCCTCCC AACCCTCCCC GTGCGGAGTG GTGTCCAGAG CAGGCAGGGC 60
CGGCTGCGGG ATGCCTCACG CAACACAGCT GTACCAGCAT GTACCAGAGA AACGCTGGCC 120
CATCGTGTAC TCTCCACGTT ACAACATCAC CTTCATGGGC CTAGAGAAGC TGCACCCCTT 180
TGATGCTGGG AAATGGGGCA AGGTGATCAA CTTCCTGAAA GAAGAGAAGC TGCTGTCTGA 240
TGGCATGCTG GTGGAGGCGA GGGAGGCCTC GGAGGAGGAC CTGCTGGTGG TGCACACAAG 300
GCGCTATCTC AACGAGCTGA AGTGGTCCTT TGTGGTGGCT ACCATCACTG AGATCCCCCC 360
TGTCATCTTT CTCCCCAACT TCCTTGTGCA GAGGAAGGTG TTGAGGCCCC TGCGGACCCA 420
GACTGGAGGC ACCATCATGG CGGGGAAGCT GGCTGTGGAA CGAGGCTGGG CCATCAATGT 480
TGGTGGTGGC TTCCACCACT GCTCCAGTGA CCGTGGTGGG GGCTTCTGTG CCTATGCAGA 540
CATCACACTG GCTATCAAGT TCCTGTTTGA ACGTGTGGAA GGCATTTCCA GAGCTACCAT 600
CATTGATCTG GATGCCCACC AGGGCAATGG GCACGAGCGA GACTTCATGG GCGACAAGCG 660
TGTATATATC ATGGATGTTT ACAACCGCCA CATCTACCCC GGGGATCGCT TTGCTAAAGA 720
GGCCATCAGG CGGAAGGTGG AGTTGGAGTG GGGCACAGAA GATGAGGAGT ATCTGGAGAA 780
GGTGGAGAGG AATGTGAGGA GGTCCCTCCA GGAGCACCTG CCTGATGTTG TGGTGTACAA 840
CGCCGGCACA GACGTCCTGG AGGGAGACCG CCTTGGCGGG CTGTCCATCA GCCCAGCGGG 900
CATTGTGAAG AGGGATGAAG TGGTTTTCCG GGTGGTCCGA GCCCATGATA TACCCATCCT 960
CATGGTGACC TCGGGTGGGT ACCAGAAGCG CACAGCCCGC ATTATCGCCG ACTCCATCCT 1020
CAATTTGCAT GACCTGGGGC TCATTGGGCC TGAGTTTCCC TATGTCCCGG CACGGAACTC 1080
AAGCATCCCC CTGCTTTCCC GTGCTGTGCC TTGACGGCTA CTCACAGAAC ATTATCATAC 1140
CTGCCCCCCC ACCCCATCCA CCCGCCCACC CGCCTGTGTT TGTTGCTGTC AAGACAGCTG 1200
CCAGTGAGCA TGGAGGGGCA GGAAGAGCAG GAGCCAGCCT TGCTGGCCAT TCCTCCACTC 1260
CCCACCAGGT GCCCAAGGGT CTCTGGGCCT TGGGGTGGAA GAGCTGAGTC CCGGGGAGGA 1320
GCCCACTGGG ATGCAAGCAG GTCATCAGGA GTCAGGGAAG ACAGCTTAGC TGCAGCCACA 1380
GGGAGGACCT CTGGGATGGG GTGCCTGCTG TCCAGATCAG CCAGAAGAAG GGCCCTCCCT 1440
GACCCAGTTG GCTTACTTCC TCCCTTCAGT CTGGAGAGGG TCCCCTCCTG GATGATGGTG 1500
CCCATAGGTC TGAGGAAAGT TTCCATAGCC AGCCTCCAGG GGGCACTGGG TTCTCAGCTA 1560
ACAGGTAATA GTCTCTGATA GAGATTTGGA GGTCTGAAGA AGGAAGCTAG GATTTTCCAG 1620
TTTGGGTTCC CTCAATAGAT CAAGCCCCCC TATGTTGATG GGGTGGGACA TTGAGAATGC 1680
CCAAGGCCCC CAACTTTGGC AGTAATCTCC TCTGTTCAGC ATGGAAACAA GTTTGGGATG 1740
AGTGTTTAGC TCAGGAGTGA CTCTCCAAGC TGGAGTTTAT AATGGGCTGC TCACCAGGAT 1800
GGAGAGAAGG TGAGGCCTAG CAGACAGGAA TGAGATGGAG ACTGGCAGCC AAGCTAGCCC 1860
TAGGTAGGGC TTGCTGGAGG GAGGGCAGCC AAGGTAACAT TTAGGTACAG TGGCCATGCA 1920
GACCTTGGGT GAGCTGCAGT CTCCAGTGGC CTCACCCAAA GTGCCCAATT TTCATCTCTG 1980
GGGCCCCAAG GTCTACCTGC CCTCCGGCCA TTCTACCCTG AAGGGACAGC CAGGGCCCTC 2040
CATGATGTAG GCAGGAAAGC ACCCACCCCT AGCCAGTGAT TGGCAGCATA ACCAAAGGCA 2100
CAGGGGGTAA GAGGATGTGG GCCAGCTGGG CTTCCTCCTG CCCTGGATCT GCCCCAACTA 2160
CAGGACTCAT ATTCATTACC ATGTGGGTAT TCCCACAGCC TTCATGGCGT CCTTCATGCT 2220
CCCTCTGCTG GAGTTGGGAG GATGCCAAAG TCACCAGTTG TCTAAACCAC TGACCTAGAC 2280
CAAACCCCAC AGTACTAATG CAGCTCCACA CCCCTCTGCC ATGACCTCTC TGCATCTGAC 2340
TGGAGGTTCC TCCCAGGACA CTGGGGAGTG GTGACAGCAG TCTGTTACTG TGGAGTTTCT 2400
CTCTGAGTAC CATACAGGCT CCAGGTTGTT GCTGTGTGTT CTGAGGTAGA CAGACCTGCC 2460
TCCTGAGGAC CACTGGAAAT AAAGATTCAA AATTCACCAA TCCAGACACC G
2512Nucleotide Fasta Sequence
>ENSRNOP00000008962.5|Class-I|Rattus norvegicus
CTCCCCGCTACACCCCTCCCAACCCTCCCCGTGCGGAGTGGTGTCCAGAGCAGGCAGGGCCGGCTGCGGGATGCCTCACGCAACACAGCTGTACCAGCATGTACCAGAGAAACGCTGGCCCATCGTGTACTCTCCACGTTACAACATCACCTTCATGGGCCTAGAGAAGCTGCACCCCTTTGATGCTGGGAAATGGGGCAAGGTGATCAACTTCCTGAAAGAAGAGAAGCTGCTGTCTGATGGCATGCTGGTGGAGGCGAGGGAGGCCTCGGAGGAGGACCTGCTGGTGGTGCACACAAGGCGCTATCTCAACGAGCTGAAGTGGTCCTTTGTGGTGGCTACCATCACTGAGATCCCCCCTGTCATCTTTCTCCCCAACTTCCTTGTGCAGAGGAAGGTGTTGAGGCCCCTGCGGACCCAGACTGGAGGCACCATCATGGCGGGGAAGCTGGCTGTGGAACGAGGCTGGGCCATCAATGTTGGTGGTGGCTTCCACCACTGCTCCAGTGACCGTGGTGGGGGCTTCTGTGCCTATGCAGACATCACACTGGCTATCAAGTTCCTGTTTGAACGTGTGGAAGGCATTTCCAGAGCTACCATCATTGATCTGGATGCCCACCAGGGCAATGGGCACGAGCGAGACTTCATGGGCGACAAGCGTGTATATATCATGGATGTTTACAACCGCCACATCTACCCCGGGGATCGCTTTGCTAAAGAGGCCATCAGGCGGAAGGTGGAGTTGGAGTGGGGCACAGAAGATGAGGAGTATCTGGAGAAGGTGGAGAGGAATGTGAGGAGGTCCCTCCAGGAGCACCTGCCTGATGTTGTGGTGTACAACGCCGGCACAGACGTCCTGGAGGGAGACCGCCTTGGCGGGCTGTCCATCAGCCCAGCGGGCATTGTGAAGAGGGATGAAGTGGTTTTCCGGGTGGTCCGAGCCCATGATATACCCATCCTCATGGTGACCTCGGGTGGGTACCAGAAGCGCACAGCCCGCATTATCGCCGACTCCATCCTCAATTTGCATGACCTGGGGCTCATTGGGCCTGAGTTTCCCTATGTCCCGGCACGGAACTCAAGCATCCCCCTGCTTTCCCGTGCTGTGCCTTGACGGCTACTCACAGAACATTATCATACCTGCCCCCCCACCCCATCCACCCGCCCACCCGCCTGTGTTTGTTGCTGTCAAGACAGCTGCCAGTGAGCATGGAGGGGCAGGAAGAGCAGGAGCCAGCCTTGCTGGCCATTCCTCCACTCCCCACCAGGTGCCCAAGGGTCTCTGGGCCTTGGGGTGGAAGAGCTGAGTCCCGGGGAGGAGCCCACTGGGATGCAAGCAGGTCATCAGGAGTCAGGGAAGACAGCTTAGCTGCAGCCACAGGGAGGACCTCTGGGATGGGGTGCCTGCTGTCCAGATCAGCCAGAAGAAGGGCCCTCCCTGACCCAGTTGGCTTACTTCCTCCCTTCAGTCTGGAGAGGGTCCCCTCCTGGATGATGGTGCCCATAGGTCTGAGGAAAGTTTCCATAGCCAGCCTCCAGGGGGCACTGGGTTCTCAGCTAACAGGTAATAGTCTCTGATAGAGATTTGGAGGTCTGAAGAAGGAAGCTAGGATTTTCCAGTTTGGGTTCCCTCAATAGATCAAGCCCCCCTATGTTGATGGGGTGGGACATTGAGAATGCCCAAGGCCCCCAACTTTGGCAGTAATCTCCTCTGTTCAGCATGGAAACAAGTTTGGGATGAGTGTTTAGCTCAGGAGTGACTCTCCAAGCTGGAGTTTATAATGGGCTGCTCACCAGGATGGAGAGAAGGTGAGGCCTAGCAGACAGGAATGAGATGGAGACTGGCAGCCAAGCTAGCCCTAGGTAGGGCTTGCTGGAGGGAGGGCAGCCAAGGTAACATTTAGGTACAGTGGCCATGCAGACCTTGGGTGAGCTGCAGTCTCCAGTGGCCTCACCCAAAGTGCCCAATTTTCATCTCTGGGGCCCCAAGGTCTACCTGCCCTCCGGCCATTCTACCCTGAAGGGACAGCCAGGGCCCTCCATGATGTAGGCAGGAAAGCACCCACCCCTAGCCAGTGATTGGCAGCATAACCAAAGGCACAGGGGGTAAGAGGATGTGGGCCAGCTGGGCTTCCTCCTGCCCTGGATCTGCCCCAACTACAGGACTCATATTCATTACCATGTGGGTATTCCCACAGCCTTCATGGCGTCCTTCATGCTCCCTCTGCTGGAGTTGGGAGGATGCCAAAGTCACCAGTTGTCTAAACCACTGACCTAGACCAAACCCCACAGTACTAATGCAGCTCCACACCCCTCTGCCATGACCTCTCTGCATCTGACTGGAGGTTCCTCCCAGGACACTGGGGAGTGGTGACAGCAGTCTGTTACTGTGGAGTTTCTCTCTGAGTACCATACAGGCTCCAGGTTGTTGCTGTGTGTTCTGAGGTAGACAGACCTGCCTCCTGAGGACCACTGGAAATAAAGATTCAAAATTCACCAATCCAGACACCG
|
| Sequence Source |
Ensembl |
| Keyword |
KW-0181--Complete proteome
KW-0378--Hydrolase
KW-1185--Reference proteome
--
|
| Interpro |
IPR000286--His_deacetylse
IPR023801--His_deacetylse_dom
|
| PROSITE |
|
| Pfam |
PF00850--Hist_deacetyl
|
| Gene Ontology |
GO:0070062--C:extracellular exosome
GO:0000118--C:histone deacetylase complex
GO:0005634--C:nucleus
GO:0005886--C:plasma membrane
GO:0004407--F:histone deacetylase activity
GO:0014003--P:oligodendrocyte development
|
| Orthology |
|
| Created Date |
25-Jun-2016 |
