| Tag |
Content |
| WERAM ID |
WERAM-Art-0082 |
| Ensembl Protein ID |
AT3G44680.1 |
| Uniprot Accession |
Q8H0W2; HDA9_ARATH; Q9M1N6
|
| Genbank Protein ID |
NP_190054.2
|
| Protein Name |
Histone deacetylase 9 |
| Genbank Nucleotide ID |
NM_114336.3
|
| Gene Name |
HDA9;At3g44680;T18B22.80 |
| Ensembl Information |
|
| Details |
| Type |
Family |
Domain |
Substrates |
AA |
References (PMIDs) |
| HDAC |
Class-I |
Histone deacetylase |
H2A; H2B; H3; H4 |
K |
26689639
|
|
| Status |
Reviewed |
| Classification |
| Type |
Family |
E-value |
Score |
Start |
End |
| HDAC |
Class-I |
6.80e-163 |
542.4 |
6 |
317 |
|
| Organism |
Arabidopsis thaliana |
| NCBI Taxa ID |
3702 |
Functional Description
(View)Functional Description
Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes (By similarity). |
Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes (By similarity).
|
| Domain Profile |
HDAC Class-I
class-1.txt 2 kvayaydedvgeyhygqkhpmkpkrlsltheLvlnyglskkleivkpkkasaeellkfhseeyieflkkvepenaeelskelkkfnvgedcPvfdglf 99
k++y+yd dvg++++g +hpmkp+rl++th+L+l+ygl+ k+e+++p+ka e+++fhs +y+efl++++pen++ +++e++++n+gedcPvf++lf
AT3G44680.1 6 KISYFYDGDVGSVYFGPNHPMKPHRLCMTHHLILAYGLHSKMEVYRPHKAYPIEMAQFHSPDYVEFLQRINPENQNLFPNEMARYNLGEDCPVFEDLF 103
689*********************************************************************************************** PP
class-1.txt 100 eycqlitGasleaakkLnkkeadiainwaGGlhhakkseasGfcyvnDivlailellkkhkrvlyididlhhGDgveeafyttdrvmtvsfhkygeef 197
e+cql++G++++aa++Ln+k +diainwaGGlhhakk++asGfcy+nD+vl+ilellk+h+rvlyidid+hhGDgveeafy+tdrvmtvsfhk+g++f
AT3G44680.1 104 EFCQLYAGGTIDAARRLNNKLCDIAINWAGGLHHAKKCDASGFCYINDLVLGILELLKHHPRVLYIDIDVHHGDGVEEAFYFTDRVMTVSFHKFGDKF 201
************************************************************************************************** PP
class-1.txt 198 fPgtGdlsdvgaekgkyyavnvPlkdgidDesyekifksviskvieafePeavvlqcGaDslagDrlgefnlsikghaecvkfvksfnlpllvlGGGG 295
fPgtGd++++g+ +gk+ya+nvPlkdgidD+s++++f+++iskv+e+++P a+vlqcGaDsla+Drlg+fnlsi+ghaecvkfvk+fnlpllv GGGG
AT3G44680.1 202 FPGTGDVKEIGEREGKFYAINVPLKDGIDDSSFNRLFRTIISKVVEIYQPGAIVLQCGADSLARDRLGCFNLSIDGHAECVKFVKKFNLPLLVTGGGG 299
************************************************************************************************** PP
class-1.txt 296 YtlrnvaRcwtyetavvl 313
Yt++nvaRcwt+et+++l
AT3G44680.1 300 YTKENVARCWTVETGILL 317
****************97 PP
|
Protein Sequence
(Fasta) | MRSKDKISYF YDGDVGSVYF GPNHPMKPHR LCMTHHLILA YGLHSKMEVY RPHKAYPIEM 60
AQFHSPDYVE FLQRINPENQ NLFPNEMARY NLGEDCPVFE DLFEFCQLYA GGTIDAARRL 120
NNKLCDIAIN WAGGLHHAKK CDASGFCYIN DLVLGILELL KHHPRVLYID IDVHHGDGVE 180
EAFYFTDRVM TVSFHKFGDK FFPGTGDVKE IGEREGKFYA INVPLKDGID DSSFNRLFRT 240
IISKVVEIYQ PGAIVLQCGA DSLARDRLGC FNLSIDGHAE CVKFVKKFNL PLLVTGGGGY 300
TKENVARCWT VETGILLDTE LPNEIPENDY IKYFAPDFSL KIPGGHIENL NTKSYISSIK 360
VQILENLRYI QHAPSVQMQE VPPDFYIPDF DEDEQNPDVR ADQRSRDKQI QRDDEYFDGD 420
NDNDAS 426Protein Fasta Sequence
>AT3G44680.1|HDA9;At3g44680;T18B22.80|Arabidopsis thaliana
MRSKDKISYFYDGDVGSVYFGPNHPMKPHRLCMTHHLILAYGLHSKMEVYRPHKAYPIEMAQFHSPDYVEFLQRINPENQNLFPNEMARYNLGEDCPVFEDLFEFCQLYAGGTIDAARRLNNKLCDIAINWAGGLHHAKKCDASGFCYINDLVLGILELLKHHPRVLYIDIDVHHGDGVEEAFYFTDRVMTVSFHKFGDKFFPGTGDVKEIGEREGKFYAINVPLKDGIDDSSFNRLFRTIISKVVEIYQPGAIVLQCGADSLARDRLGCFNLSIDGHAECVKFVKKFNLPLLVTGGGGYTKENVARCWTVETGILLDTELPNEIPENDYIKYFAPDFSLKIPGGHIENLNTKSYISSIKVQILENLRYIQHAPSVQMQEVPPDFYIPDFDEDEQNPDVRADQRSRDKQIQRDDEYFDGDNDNDAS |
Nucleotide Sequence
(Fasta) | GTTCTTCTCT TCTCTCTTCT TCTTTTCGCT TCGTTGCTGC TCTCTTCTCG GCTCCGCCGG 60
AGAATCGTGA AATCTCTGCG ACTTCATCAA TGAAGAAATC GTCTCATCTC TCTACTGAAT 120
CTAAGCAGAC CTGAAATATC TCTGTATAAT CTTTCTTTAA GATTGATTTC GTACGATCTT 180
CGTGTCTTTT CTTCTTTAAG AGATGCGTTC CAAGGACAAA ATCTCTTACT TTTATGATGG 240
GGATGTGGGG AGTGTCTATT TTGGTCCGAA TCACCCGATG AAACCTCACA GGCTTTGTAT 300
GACCCATCAT CTTATCCTTG CATATGGCCT GCATAGCAAG ATGGAAGTTT ATCGTCCACA 360
CAAAGCATAT CCTATCGAGA TGGCTCAGTT CCATTCTCCT GACTATGTAG AGTTCCTGCA 420
ACGAATTAAT CCAGAAAACC AGAACTTGTT CCCCAATGAA ATGGCTAGAT ATAATCTGGG 480
AGAGGATTGT CCTGTCTTTG AAGATTTGTT TGAATTTTGT CAACTTTACG CCGGCGGAAC 540
CATAGATGCT GCACGCAGGT TAAACAACAA ACTCTGTGAC ATTGCTATAA ATTGGGCGGG 600
CGGGTTGCAC CATGCCAAAA AATGTGATGC ATCTGGGTTT TGCTACATCA ACGATCTCGT 660
GCTAGGAATT CTTGAGTTGT TAAAACACCA TCCCCGTGTT CTATACATAG ATATAGATGT 720
TCATCATGGT GATGGGGTTG AAGAAGCGTT TTACTTCACT GACAGAGTAA TGACTGTTAG 780
CTTTCATAAG TTTGGGGATA AGTTCTTTCC AGGGACAGGC GATGTTAAGG AAATAGGAGA 840
AAGAGAAGGG AAATTTTACG CCATTAATGT GCCGCTGAAG GATGGTATCG ATGACAGTAG 900
TTTCAACCGT CTTTTCAGGA CTATAATATC CAAGGTTGTT GAGATATATC AACCGGGTGC 960
AATTGTTCTT CAATGCGGGG CAGATTCACT AGCCAGGGAT CGACTAGGAT GCTTTAATCT 1020
CTCTATTGAT GGACATGCTG AATGTGTTAA ATTCGTGAAG AAGTTCAATC TTCCCTTACT 1080
GGTTACAGGA GGTGGAGGAT ACACAAAGGA GAATGTAGCT CGTTGTTGGA CCGTTGAGAC 1140
TGGCATTCTT TTGGACACAG AACTTCCTAA TGAGATTCCT GAAAACGACT ACATAAAGTA 1200
TTTTGCGCCG GATTTTTCTT TGAAGATACC GGGTGGTCAC ATTGAGAATC TTAATACCAA 1260
ATCGTACATC AGTTCCATCA AAGTGCAGAT TTTGGAGAAT TTGCGATACA TTCAACACGC 1320
TCCAAGCGTA CAAATGCAGG AGGTTCCACC GGATTTCTAC ATACCGGATT TTGATGAAGA 1380
CGAACAAAAC CCGGATGTAC GTGCGGATCA GCGTTCACGG GATAAGCAGA TCCAGAGGGA 1440
TGATGAATAT TTCGATGGAG ACAACGATAA CGATGCGTCA TAAAACATCG ATTCTTAGAA 1500
ATTGTTGGTT AATTTTTTTG TTTAGTTATG AGATTTGTAA TGATATCAAC ACTTTAACGG 1560
CTACTGGGGC ACCAAAACCA CTTCTGATTG ATTCCATCTT CTTCATGTTT TCGTCTTGGT 1620
GTATATGAAT GAAGCTTTTT GGTTCACTTT CTCATCATTG TGACTTATAT AGTGATCAAA 1680
TTCGTTATAT ATTGTA
1697Nucleotide Fasta Sequence
>AT3G44680.1|Class-I|Arabidopsis thaliana
GTTCTTCTCTTCTCTCTTCTTCTTTTCGCTTCGTTGCTGCTCTCTTCTCGGCTCCGCCGGAGAATCGTGAAATCTCTGCGACTTCATCAATGAAGAAATCGTCTCATCTCTCTACTGAATCTAAGCAGACCTGAAATATCTCTGTATAATCTTTCTTTAAGATTGATTTCGTACGATCTTCGTGTCTTTTCTTCTTTAAGAGATGCGTTCCAAGGACAAAATCTCTTACTTTTATGATGGGGATGTGGGGAGTGTCTATTTTGGTCCGAATCACCCGATGAAACCTCACAGGCTTTGTATGACCCATCATCTTATCCTTGCATATGGCCTGCATAGCAAGATGGAAGTTTATCGTCCACACAAAGCATATCCTATCGAGATGGCTCAGTTCCATTCTCCTGACTATGTAGAGTTCCTGCAACGAATTAATCCAGAAAACCAGAACTTGTTCCCCAATGAAATGGCTAGATATAATCTGGGAGAGGATTGTCCTGTCTTTGAAGATTTGTTTGAATTTTGTCAACTTTACGCCGGCGGAACCATAGATGCTGCACGCAGGTTAAACAACAAACTCTGTGACATTGCTATAAATTGGGCGGGCGGGTTGCACCATGCCAAAAAATGTGATGCATCTGGGTTTTGCTACATCAACGATCTCGTGCTAGGAATTCTTGAGTTGTTAAAACACCATCCCCGTGTTCTATACATAGATATAGATGTTCATCATGGTGATGGGGTTGAAGAAGCGTTTTACTTCACTGACAGAGTAATGACTGTTAGCTTTCATAAGTTTGGGGATAAGTTCTTTCCAGGGACAGGCGATGTTAAGGAAATAGGAGAAAGAGAAGGGAAATTTTACGCCATTAATGTGCCGCTGAAGGATGGTATCGATGACAGTAGTTTCAACCGTCTTTTCAGGACTATAATATCCAAGGTTGTTGAGATATATCAACCGGGTGCAATTGTTCTTCAATGCGGGGCAGATTCACTAGCCAGGGATCGACTAGGATGCTTTAATCTCTCTATTGATGGACATGCTGAATGTGTTAAATTCGTGAAGAAGTTCAATCTTCCCTTACTGGTTACAGGAGGTGGAGGATACACAAAGGAGAATGTAGCTCGTTGTTGGACCGTTGAGACTGGCATTCTTTTGGACACAGAACTTCCTAATGAGATTCCTGAAAACGACTACATAAAGTATTTTGCGCCGGATTTTTCTTTGAAGATACCGGGTGGTCACATTGAGAATCTTAATACCAAATCGTACATCAGTTCCATCAAAGTGCAGATTTTGGAGAATTTGCGATACATTCAACACGCTCCAAGCGTACAAATGCAGGAGGTTCCACCGGATTTCTACATACCGGATTTTGATGAAGACGAACAAAACCCGGATGTACGTGCGGATCAGCGTTCACGGGATAAGCAGATCCAGAGGGATGATGAATATTTCGATGGAGACAACGATAACGATGCGTCATAAAACATCGATTCTTAGAAATTGTTGGTTAATTTTTTTGTTTAGTTATGAGATTTGTAATGATATCAACACTTTAACGGCTACTGGGGCACCAAAACCACTTCTGATTGATTCCATCTTCTTCATGTTTTCGTCTTGGTGTATATGAATGAAGCTTTTTGGTTCACTTTCTCATCATTGTGACTTATATAGTGATCAAATTCGTTATATATTGTA
|
| Sequence Source |
Ensembl |
| Keyword |
KW-0156--Chromatin regulator
KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0678--Repressor
KW-0804--Transcription
KW-0805--Transcription regulation
--
|
| Interpro |
IPR000286--His_deacetylse
IPR003084--His_deacetylse_1
IPR023801--His_deacetylse_dom
|
| PROSITE |
|
| Pfam |
PF00850--Hist_deacetyl
|
| Gene Ontology |
GO:0005634--C:nucleus
GO:0032041--F:NAD-dependent histone deacetylase activity (H3-K14 specific)
GO:0010187--P:negative regulation of seed germination
GO:0006355--P:regulation of transcription, DNA-templated
GO:0006351--P:transcription, DNA-templated
|
| Orthology |
|
| Created Date |
25-Jun-2016 |
