Brassica rapa      Ac_Reader      Bromodomain

※ Bromodomain family introduction

    Bromodomain: Bromodomains (BRDs) are protein interaction modules that exclusively recognize acetylation motifs. BRDs are evolutionarily conserved and present in diverse nuclear proteins comprising HATs (GCN5, PCAF), ATP-dependent chromatin-remodeling complexes (BAZ1B), helicases (SMARCA), methyltransferases (MLL, ASH1L), transcriptional coactivators (TRIM/TIF1, TAFs) transcriptional mediators (TAF1), nuclear-scaffolding proteins(PB1), and the BET family. Despite large sequence variations, all BRD modules share a conserved fold that comprises a left-handed bundle of four a helices, linked by loop regions of variablelength, which line the Kac binding site and determine binding specificity. (1)

Reference
1. P. Filippakopoulos, S. Picaud, M. Mangos, T. Keates, J.P. Lambert, D. Barsyte-Lovejoy, I. Felletar, R. Volkmer, S. Müller, T. Pawson,et al.Histone recognition and large-scale structural analysis of the human bromodomain family. Cell.2012;149(1):214-231. PMID: 22464331.



There are 39 genes.  Reviewed (0 or Unreviewed (39

No.StatusWERAM IDGene/Alias Name
1
WERAM-Brr-0020
2
WERAM-Brr-0022
3
WERAM-Brr-0024
4
WERAM-Brr-0029
5
WERAM-Brr-0036
6
WERAM-Brr-0037
7
WERAM-Brr-0039
8
WERAM-Brr-0041
GTE3
9
WERAM-Brr-0054
10
WERAM-Brr-0064
11
WERAM-Brr-0066
GTE6
12
WERAM-Brr-0072
13
WERAM-Brr-0073
14
WERAM-Brr-0074
15
WERAM-Brr-0076
16
WERAM-Brr-0077
17
WERAM-Brr-0082
18
WERAM-Brr-0083
19
WERAM-Brr-0087
20
WERAM-Brr-0096
21
WERAM-Brr-0107
22
WERAM-Brr-0110
23
WERAM-Brr-0114
24
WERAM-Brr-0122
GTE7
25
WERAM-Brr-0125
26
WERAM-Brr-0126
27
WERAM-Brr-0127
28
WERAM-Brr-0152
29
WERAM-Brr-0153
30
WERAM-Brr-0154
BRD4
31
WERAM-Brr-0160
32
WERAM-Brr-0161
33
WERAM-Brr-0169
34
WERAM-Brr-0175
35
WERAM-Brr-0176
36
WERAM-Brr-0179
37
WERAM-Brr-0188
TAF1
38
WERAM-Brr-0194
39
WERAM-Brr-0196