WERAM Information

Tag Content
WERAM ID WERAM-Art-0117
Ensembl Protein ID AT5G05610.2
Uniprot Accession Q9FFF5; ALFL1_ARATH
Genbank Protein ID NP_196180.1; NP_850775.1
Protein Name PHD finger protein ALFIN-LIKE 1
Genbank Nucleotide ID NM_120643.1; NM_180444.2
Gene Name ALFL1;AL1At5g05610;MOP10.15
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
AT5G05610 AT5G05610.2 AT5G05610.2
AT5G05610 AT5G05610.1 AT5G05610.1
Details
Type Family Domain Substrates AA References (PMIDs)
Me_Reader PHD PHD-type H3K4me3/2 K 19154204
Status Reviewed
Classification
Type Family E-value Score Start End
Me_Reader PHD 2.30e-11 44.5 186 236
Organism Arabidopsis thaliana
NCBI Taxa ID 3702
Functional Description
(View)		 Histone-binding component that specifically recognizes H3 tails trimethylated on 'Lys-4' (H3K4me3), which mark transcription start sites of virtually all active genes.
Domain Profile
  Me_Reader PHD
      PHD.txt   2 tiClvCgkddegekemvqCdeCddwfHlkCvklplsslpegkswyCpsCke 52 
                  t+C  Cg ++++++++++Cd C++w+H+kCvk++  ++++ k++ CpsC +
  AT5G05610.2 186 TLCGSCGGNYTNDEFWICCDVCERWYHGKCVKITPAKAESIKQYKCPSCCT 236
                  78********************************555554489******86 PP
Protein Sequence
(Fasta)		MAAESSNPRT VEEIFKDFSG RRSGFLRALS VDVDKFYSLC DPEMENLCLY GHPNGTWEVN 60
LPAEEVPPEL PEPALGINFA RDGMQRKDWL SLVAVHSDCW LLSVSSYFGA RLNRNERKRL 120
FSLINDLPTL FEVVTGRKPI KDGKPSMDLG SKSRNGVKRS IEGQTKSTPK LMEESYEDED 180
DEHGDTLCGS CGGNYTNDEF WICCDVCERW YHGKCVKITP AKAESIKQYK CPSCCTKKGR 240
Q 241
Nucleotide Sequence
(Fasta)		AAACTCTGGT CTCTCTCTAT CTCTCTTGTC CGTGCGCATC GGATTTTGGA AACCATTGAT 60
GCAGACCTCA ATCCATCTCT AACACCACTG ATCTATCTAC TTAGGTCTTC TCTAACAATA 120
CTTGTAATTT TCTTTCTTTT TGCTTCTTCC GTCACTACAT CTATGGCCGC TGAGTCTTCT 180
AACCCTCGCA CCGTCGAAGA GATCTTCAAG GATTTTAGCG GTCGTCGCTC CGGTTTTCTT 240
CGAGCTCTCT CCGTAGATGT TGACAAGTTC TACTCTTTAT GCGATCCGGA AATGGAGAAT 300
CTGTGTTTGT ACGGACACCC GAATGGGACA TGGGAAGTGA ATCTTCCAGC TGAGGAAGTG 360
CCTCCGGAGC TACCTGAGCC AGCTCTTGGA ATCAATTTCG CTAGAGATGG TATGCAGCGT 420
AAAGATTGGC TCTCTTTAGT TGCTGTCCAC AGTGATTGTT GGTTACTCTC TGTTTCTTCT 480
TACTTCGGCG CTCGTCTTAA TCGCAATGAG AGGAAACGTC TATTTAGTCT GATCAACGAT 540
CTCCCAACTC TCTTTGAAGT AGTGACGGGT AGGAAACCCA TCAAAGACGG TAAACCAAGC 600
ATGGATCTCG GAAGCAAATC CAGAAACGGC GTAAAGAGAT CAATTGAAGG GCAGACAAAG 660
AGCACGCCGA AACTAATGGA AGAGAGCTAT GAAGATGAAG ACGATGAGCA TGGAGACACA 720
CTCTGTGGAA GTTGTGGAGG AAACTACACA AACGACGAGT TCTGGATATG TTGTGATGTG 780
TGTGAACGTT GGTACCATGG GAAGTGTGTG AAGATAACAC CAGCCAAAGC AGAGAGCATC 840
AAGCAATACA AATGCCCTTC TTGCTGCACT AAGAAAGGAA GACAGTGAGT GAATGAATGA 900
ATTCTCAAAA AGGGCGTTTT AAAATAGTAA TGAGGGTATG AGACATGGAG AGAGTCATAG 960
AGACACCAGC TGCTTAGAGA GCTTCGTCAA CTTTTGATCA AATATGCCAT GTGTTTGTAT 1020
ATGTAGCGAC TCTACTACTT TCATCGTTTA TGTGTGTAAT CTCTCTTTAG GCTAATATAA 1080
AAAAAAATAT TCTTATGTAA GGTTGATCTT CATAATCTCT CATATGGTAT TTTAACTAAG 1140
AGTTTGTACT GACAAAATTT AAGTGGTTAT AGTGGTGTTT TGTTATGTAC AC 1193
Sequence Source Ensembl
Keyword

KW-0007--Acetylation
KW-0156--Chromatin regulator
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0804--Transcription
KW-0805--Transcription regulation
KW-0862--Zinc
KW-0863--Zinc-finger
--
Interpro

IPR021998--Alfin
IPR019786--Zinc_finger_PHD-type_CS
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD
PROSITE

PS01359--ZF_PHD_1
PS50016--ZF_PHD_2
Pfam

PF12165--DUF3594
PF00628--PHD
Gene Ontology

GO:0005634--C:nucleus
GO:0035064--F:methylated histone binding
GO:0044212--F:transcription regulatory region DNA binding
GO:0008270--F:zinc ion binding
GO:0016568--P:chromatin modification
GO:0006355--P:regulation of transcription, DNA-templated
GO:0006351--P:transcription, DNA-templated
Orthology
WERAM ID Ensembl Protein ID Species Identity E-value Score
WERAM-Arl-0100 fgenesh2_kg.6__ 497__ AT5G05610.2 Arabidopsis lyrata 100 6e-122 433
WERAM-Brr-0044 Bra009121.1-P Brassica rapa 89 2e-106 382
WERAM-Bro-0102 Bo5g136750.1 Brassica oleracea 85 3e-103 371
WERAM-Sot-0075 PGSC0003DMT400059399 Solanum tuberosum 80 9e-101 363
WERAM-Prp-0085 EMJ19499 Prunus persica 79 5e-99 357
WERAM-Sol-0105 Solyc09g005360.2.1 Solanum lycopersicum 79 8e-97 350
WERAM-Glm-0003 GLYMA01G29950.1 Glycine max 78 1e-95 346
WERAM-Pot-0155 POPTR_0016s12420.1 Populus trichocarpa 80 1e-95 346
WERAM-Thc-0059 EOY07191 Theobroma cacao 78 4e-94 341
WERAM-Viv-0060 VIT_08s0105g00360.t01 Vitis vinifera 77 1e-93 339
WERAM-Mua-0047 GSMUA_Achr2P18960_001 Musa acuminata 73 6e-93 337
WERAM-Amt-0010 ERN05231 Amborella trichopoda 76 2e-91 332
WERAM-Met-0092 KEH28874 Medicago truncatula 78 4e-91 331
WERAM-Orni-0073 ONIVA07G06790.1 Oryza nivara 69 5e-84 307
WERAM-Ors-0066 OS07T0233300-01 Oryza sativa 69 5e-84 307
WERAM-Orr-0075 ORUFI07G08080.1 Oryza rufipogon 69 5e-84 307
WERAM-Ori-0080 BGIOSGA024567-PA Oryza indica 69 5e-84 307
WERAM-Lep-0074 LPERR07G06880.1 Leersia perrieri 69 6e-84 307
WERAM-Orm-0069 OMERI07G06560.1 Oryza meridionalis 69 1e-83 306
WERAM-Orgl-0051 OGLUM05G06240.1 Oryza glumaepatula 69 1e-83 306
WERAM-Org-0074 ORGLA07G0067800.1 Oryza glaberrima 69 1e-83 306
WERAM-Orp-0071 OPUNC07G07630.1 Oryza punctata 69 3e-83 305
WERAM-Sob-0020 Sb02g006980.1 Sorghum bicolor 67 2e-81 298
WERAM-Sem-0147 EFJ25244 Selaginella moellendorffii 69 6e-79 290
WERAM-Brd-0027 BRADI1G53660.1 Brachypodium distachyon 64 4e-78 288
WERAM-Zem-0036 GRMZM2G047316_P01 Zea mays 63 6e-78 287
WERAM-Orbr-0082 OB07G15980.1 Oryza brachyantha 68 2e-77 285
WERAM-Sei-0134 Si037171m Setaria italica 62 5e-77 284
WERAM-Php-0090 PP1S371_53V6.1 Physcomitrella patens 64 6e-77 284
WERAM-Orb-0041 OBART03G38930.1 Oryza barthii 64 1e-76 283
WERAM-Orl-0033 KN538803.1_FGP006 Oryza longistaminata 63 6e-75 277
WERAM-Hov-0103 MLOC_72504.1 Hordeum vulgare 60 6e-72 267
WERAM-Tra-0033 Traes_1DS_59542CFCE.1 Triticum aestivum 60 1e-71 266
WERAM-Aet-0106 EMT19247 Aegilops tauschii 59 5e-70 261
Created Date 25-Jun-2016