Tag |
Content |
WERAM ID |
WERAM-Hos-0020 |
Ensembl Protein ID |
ENSP00000358092.4 |
Uniprot Accession |
O75626; PRDM1_HUMAN; B2REA6; E1P5E0; Q86WM7
|
Genbank Protein ID |
NP_001189.2; NP_878911.1; XP_011534365.1
|
Protein Name |
PR domain zinc finger protein 1 |
Genbank Nucleotide ID |
NM_001198.3; NM_182907.2; XM_011536063.1
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Gene Name |
PRDM1;BLIMP1;PRDI-BF1 |
Ensembl Information |
|
Details |
Type |
Family |
Domain |
Substrates |
AA |
References (PMIDs) |
HMT |
RIZ |
SET |
|
K |
25537518
|
|
Status |
Reviewed |
Classification |
Type |
Family |
E-value |
Score |
Start |
End |
HMT |
RIZ |
1.50e-42 |
146.7 |
86 |
201 |
|
Organism |
Homo sapiens |
NCBI Taxa ID |
9606 |
Functional Description (View)Functional Description
Transcriptional repressor that binds specifically to the PRDI element in the promoter of the beta-interferon gene (PubMed:1851123). Drives the maturation of B-lymphocytes into Ig secreting cells (PubMed:12626569). |
Transcriptional repressor that binds specifically to the PRDI element in the promoter of the beta-interferon gene (PubMed:1851123). Drives the maturation of B-lymphocytes into Ig secreting cells (PubMed:12626569).
|
Domain Profile |
HMT RIZ
RIZ.txt 3 velaessipkeg.lgvyakkkiekgekfGPfvGekkileeveenanekliweisedkgevkyivDasdeeksnWlryvnvArskeeqNLaal 93 + l+++++++e+ +gv++k++i+kg++fGP++Ge++++++v +nan+k++w+i+ ++ge ++++D+ +eeksnW+ryvn A+s +eqNLaa+ ENSP00000358092.4 86 NLLFKYATNSEEvIGVMSKEYIPKGTRFGPLIGEIYTNDTVPKNANRKYFWRIY-SRGELHHFIDGFNEEKSNWMRYVNPAHSPREQNLAAC 176 66889999988889****************************************.9************************************ PP RIZ.txt 94 qineqifYktikdIepdeELLvwyk 118 q++++i+++tik+I++++ELLvwy+ ENSP00000358092.4 177 QNGMNIYFYTIKPIPANQELLVWYC 201 ************************6 PP
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Protein Sequence (Fasta) | MLDICLEKRV GTTLAAPKCN SSTVRFQGLA EGTKGTMKMD MEDADMTLWT EAEFEEKCTY 60 IVNDHPWDSG ADGGTSVQAE ASLPRNLLFK YATNSEEVIG VMSKEYIPKG TRFGPLIGEI 120 YTNDTVPKNA NRKYFWRIYS RGELHHFIDG FNEEKSNWMR YVNPAHSPRE QNLAACQNGM 180 NIYFYTIKPI PANQELLVWY CRDFAERLHY PYPGELTMMN LTQTQSSLKQ PSTEKNELCP 240 KNVPKREYSV KEILKLDSNP SKGKDLYRSN ISPLTSEKDL DDFRRRGSPE MPFYPRVVYP 300 IRAPLPEDFL KASLAYGIER PTYITRSPIP SSTTPSPSAR SSPDQSLKSS SPHSSPGNTV 360 SPVGPGSQEH RDSYAYLNAS YGTEGLGSYP GYAPLPHLPP AFIPSYNAHY PKFLLPPYGM 420 NCNGLSAVSS MNGINNFGLF PRLCPVYSNL LGGGSLPHPM LNPTSLPSSL PSDGARRLLQ 480 PEHPREVLVP APHSAFSFTG AAASMKDKAC SPTSGSPTAG TAATAEHVVQ PKATSAAMAA 540 PSSDEAMNLI KNKRNMTGYK TLPYPLKKQN GKIKYECNVC AKTFGQLSNL KVHLRVHSGE 600 RPFKCQTCNK GFTQLAHLQK HYLVHTGEKP HECQVCHKRF SSTSNLKTHL RLHSGEKPYQ 660 CKVCPAKFTQ FVHLKLHKRL HTRERPHKCS QCHKNYIHLC SLKVHLKGNC AAAPAPGLPL 720 EDLTRINEEI EKFDISDNAD RLEDVEDDIS VISVVEKEIL AVVRKEKEET GLKVSLQRNM 780 GNGLLSSGCS LYESSDLPLM KLPPSNPLPL VPVKVKQETV EPMDP 825Protein Fasta Sequence
>ENSP00000358092.4|PRDM1;BLIMP1;PRDI-BF1|Homo sapiens MLDICLEKRVGTTLAAPKCNSSTVRFQGLAEGTKGTMKMDMEDADMTLWTEAEFEEKCTYIVNDHPWDSGADGGTSVQAEASLPRNLLFKYATNSEEVIGVMSKEYIPKGTRFGPLIGEIYTNDTVPKNANRKYFWRIYSRGELHHFIDGFNEEKSNWMRYVNPAHSPREQNLAACQNGMNIYFYTIKPIPANQELLVWYCRDFAERLHYPYPGELTMMNLTQTQSSLKQPSTEKNELCPKNVPKREYSVKEILKLDSNPSKGKDLYRSNISPLTSEKDLDDFRRRGSPEMPFYPRVVYPIRAPLPEDFLKASLAYGIERPTYITRSPIPSSTTPSPSARSSPDQSLKSSSPHSSPGNTVSPVGPGSQEHRDSYAYLNASYGTEGLGSYPGYAPLPHLPPAFIPSYNAHYPKFLLPPYGMNCNGLSAVSSMNGINNFGLFPRLCPVYSNLLGGGSLPHPMLNPTSLPSSLPSDGARRLLQPEHPREVLVPAPHSAFSFTGAAASMKDKACSPTSGSPTAGTAATAEHVVQPKATSAAMAAPSSDEAMNLIKNKRNMTGYKTLPYPLKKQNGKIKYECNVCAKTFGQLSNLKVHLRVHSGERPFKCQTCNKGFTQLAHLQKHYLVHTGEKPHECQVCHKRFSSTSNLKTHLRLHSGEKPYQCKVCPAKFTQFVHLKLHKRLHTRERPHKCSQCHKNYIHLCSLKVHLKGNCAAAPAPGLPLEDLTRINEEIEKFDISDNADRLEDVEDDISVISVVEKEILAVVRKEKEETGLKVSLQRNMGNGLLSSGCSLYESSDLPLMKLPPSNPLPLVPVKVKQETVEPMDP
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Nucleotide Sequence (Fasta) | GGGAAGCCAG ACGGTTAACA CAGACAAAGT GCTGCCGTGA CACTCGGCCC TCCAGTGTTG 60 CGGAGAGGCA AGAGCAGCGA CCGCGGCACC TGTCCGCCCG GAGCTGGGAC GCGGGCGCCC 120 GGGCGGCCGG ACGAAGCGAG GAGGGACCGC CGAGGTGCGC GTCTGTGCGG CTCAGCCTGG 180 CGGGGGACGC GGGGAGAATG TGGACTGGGT AGAGATGAAC GAGACTTTTC TCAGATGTTG 240 GATATTTGCT TGGAAAAACG TGTGGGTACG ACCTTGGCTG CCCCCAAGTG TAACTCCAGC 300 ACTGTGAGGT TTCAGGGATT GGCAGAGGGG ACCAAGGGGA CCATGAAAAT GGACATGGAG 360 GATGCGGATA TGACTCTGTG GACAGAGGCT GAGTTTGAAG AGAAGTGTAC ATACATTGTG 420 AACGACCACC CCTGGGATTC TGGTGCTGAT GGCGGTACTT CGGTTCAGGC GGAGGCATCC 480 TTACCAAGGA ATCTGCTTTT CAAGTATGCC ACCAACAGTG AAGAGGTTAT TGGAGTGATG 540 AGTAAAGAAT ACATACCAAA GGGCACACGT TTTGGACCCC TAATAGGTGA AATCTACACC 600 AATGACACAG TTCCTAAGAA CGCCAACAGG AAATATTTTT GGAGGATCTA TTCCAGAGGG 660 GAGCTTCACC ACTTCATTGA CGGCTTTAAT GAAGAGAAAA GCAACTGGAT GCGCTATGTG 720 AATCCAGCAC ACTCTCCCCG GGAGCAAAAC CTGGCTGCGT GTCAGAACGG GATGAACATC 780 TACTTCTACA CCATTAAGCC CATCCCTGCC AACCAGGAAC TTCTTGTGTG GTATTGTCGG 840 GACTTTGCAG AAAGGCTTCA CTACCCTTAT CCCGGAGAGC TGACAATGAT GAATCTCACA 900 CAAACACAGA GCAGTCTAAA GCAACCGAGC ACTGAGAAAA ATGAACTCTG CCCAAAGAAT 960 GTCCCAAAGA GAGAGTACAG CGTGAAAGAA ATCCTAAAAT TGGACTCCAA CCCCTCCAAA 1020 GGAAAGGACC TCTACCGTTC TAACATTTCA CCCCTCACAT CAGAAAAGGA CCTCGATGAC 1080 TTTAGAAGAC GTGGGAGCCC CGAAATGCCC TTCTACCCTC GGGTCGTTTA CCCCATCCGG 1140 GCCCCTCTGC CAGAAGACTT TTTGAAAGCT TCCCTGGCCT ACGGGATCGA GAGACCCACG 1200 TACATCACTC GCTCCCCCAT TCCATCCTCC ACCACTCCAA GCCCCTCTGC AAGAAGCAGC 1260 CCCGACCAAA GCCTCAAGAG CTCCAGCCCT CACAGCAGCC CTGGGAATAC GGTGTCCCCT 1320 GTGGGCCCCG GCTCTCAAGA GCACCGGGAC TCCTACGCTT ACTTGAACGC GTCCTACGGC 1380 ACGGAAGGTT TGGGCTCCTA CCCTGGCTAC GCACCCCTGC CCCACCTCCC GCCAGCTTTC 1440 ATCCCCTCGT ACAACGCTCA CTACCCCAAG TTCCTCTTGC CCCCCTACGG CATGAATTGT 1500 AATGGCCTGA GCGCTGTGAG CAGCATGAAT GGCATCAACA ACTTTGGCCT CTTCCCGAGG 1560 CTGTGCCCTG TCTACAGCAA TCTCCTCGGT GGGGGCAGCC TGCCCCACCC CATGCTCAAC 1620 CCCACTTCTC TCCCGAGCTC GCTGCCCTCA GATGGAGCCC GGAGGTTGCT CCAGCCGGAG 1680 CATCCCAGGG AGGTGCTTGT CCCGGCGCCC CACAGTGCCT TCTCCTTTAC CGGGGCCGCC 1740 GCCAGCATGA AGGACAAGGC CTGTAGCCCC ACAAGCGGGT CTCCCACGGC GGGAACAGCC 1800 GCCACGGCAG AACATGTGGT GCAGCCCAAA GCTACCTCAG CAGCGATGGC AGCCCCCAGC 1860 AGCGACGAAG CCATGAATCT CATTAAAAAC AAAAGAAACA TGACCGGCTA CAAGACCCTT 1920 CCCTACCCGC TGAAGAAGCA GAACGGCAAG ATCAAGTACG AATGCAACGT TTGCGCCAAG 1980 ACTTTCGGCC AGCTCTCCAA TCTGAAGGTC CACCTGAGAG TGCACAGTGG AGAACGGCCT 2040 TTCAAATGTC AGACTTGCAA CAAGGGCTTT ACTCAGCTCG CCCACCTGCA GAAACACTAC 2100 CTGGTACACA CGGGAGAAAA GCCACATGAA TGCCAGGTCT GCCACAAGAG ATTTAGCAGC 2160 ACCAGCAATC TCAAGACCCA CCTGCGACTC CATTCTGGAG AGAAACCATA CCAATGCAAG 2220 GTGTGCCCTG CCAAGTTCAC CCAGTTTGTG CACCTGAAAC TGCACAAGCG TCTGCACACC 2280 CGGGAGCGGC CCCACAAGTG CTCCCAGTGC CACAAGAACT ACATCCATCT CTGTAGCCTC 2340 AAGGTTCACC TGAAAGGGAA CTGCGCTGCG GCCCCGGCGC CTGGGCTGCC CTTGGAAGAT 2400 CTGACCCGAA TCAATGAAGA AATCGAGAAG TTTGACATCA GTGACAATGC TGACCGGCTC 2460 GAGGACGTGG AGGATGACAT CAGTGTGATC TCTGTAGTGG AGAAGGAAAT TCTGGCCGTG 2520 GTCAGAAAAG AGAAAGAAGA AACTGGCCTG AAAGTGTCTT TGCAAAGAAA CATGGGGAAT 2580 GGACTCCTCT CCTCAGGGTG CAGCCTTTAT GAGTCATCAG ATCTACCCCT CATGAAGTTG 2640 CCTCCCAGCA ACCCACTACC TCTGGTACCT GTAAAGGTCA AACAAGAAAC AGTTGAACCA 2700 ATGGATCCTT AAGATTTTCA GAAAACACTT ATTTTGTTTC TTAAGTTATG ACTTGGTGAG 2760 TCAGGGTGCC TGTAGGAAGT GGCTTGTACA TAATCCCAGC TCTGCAAAGC TCTCTCGACA 2820 GCAAATGGTT TCCCCTCACC TCTGGAATTA AAGAAGGAAC TCCAAAGTTA CTGAAATCTC 2880 AGGGCATGAA CAAGGCAAAG GCCATATATA TATATATATA TATATCTGTA TACATATTAT 2940 ATATACTTAT TTACACCTGT GTCTATATAT TTGCCCCTGT GTATTTTGAA TATTTGTGTG 3000 GACATGTTTG CATAGCCTTC CCATTACTAA GACTATTACC TAGTCATAAT TATTTTTTCA 3060 ATGATAATCC TTCATAATTT ATTATACAAT TTATCATTCA GAAAGCAATA ATTAAAAAAG 3120 TTTACAATGA CTGGAAAGAT TCCTTGTAAT TTGAGTATAA ATGTATTTTT GTCTTGTGGC 3180 CATTCTTTGT AGATAATTTC TGCACATCTG TATAAGTACC TAAGATTTAG TTAAACAAAT 3240 ATATGACTTC AGTCAACCTC TCTCTCTAAT AATGGTTTGA AAATGAGGTT TGGGTAATTG 3300 CCAATGTTGG ACAGTTGATG TGTTCATTCC TGGGATCCTA TCATTTGAAC AGCATTGTAC 3360 ATAACTTGGG GGTATGTGTG CAGGATTACC CAAGAATAAC TTAAGTAGAA GAAACAAGAA 3420 AGGGAATCTT GTATATTTTT GTTGATAGTT CATGTTTTTC CCCCAGCCAC AATTTTACCG 3480 GAAGGGTGAC AGGAAGGCTT TACCAACCTG TCTCTCCCTC CAAAAGAGCA GAATCCTCCC 3540 ACCGCCCTGC CCTCCCCACC GAGTCCTGTG GCCATTCAGA GCGGCCACAT GACTTTTGCA 3600 TCCATTGTAT TATCAGAAAA TGTGAAGAAG AAAAAAATGC CATGTTTTAA AACCACTGCG 3660 AAAATTTCCC CAAAGCATAG GTGGCTTTGT GTGTGTGCGA TTTGGGGGCT TGAGTCTGGG 3720 TGGTGTTTTG TTGTTGGTTT TTGTTGCTTT TTTTTTTTTT TTTTTTTTAA TGTCAAAATT 3780 GCACAAACAT GGTGCTCTAC CAGGAAGGAT TCGAGGTAGA TAGGCTCAGG CCACACTTTA 3840 AAAACAAACA CACAAACAAC AAAAAACGGG TATTCTAGTC ATCTTGGGGT AAAAGCGGGT 3900 AATGAACATT CCTATCCCCA ACACATCAAT TGTATTTTTT CTGTAAAACT CAGATTTTCC 3960 TCAGTATTTG TGTTTTTACA TTTTATGGTT AATTTAATGG AAGATGAAAG GGCATTGCAA 4020 AGTTGTTCAA CAACAGTTAC CTCATTGAGT GTGTCCAGTA GTGCAGGAAA TGATGTCTTA 4080 TCTAATGATT TGCTTCTCTA GAGGAGAAAC CGAGTAAATG TGCTCCAGCA AGATAGACTT 4140 TGTGTTATTC TATCTTTTAT TCTGCTAAGC CCAAAGATTA CATGTTGGTG TTCAAAGTGT 4200 AGCAAAAAAT GATGTATATT TATAAATCTA TTTATACCAC TATATCATAT GTATATATAT 4260 TTATAACCAC TTAAATTGTG AGCCAAGCCA TGTAAAAGAT CTACTTTTTC TAAGGGCAAA 4320 AAAAAAAAAA AAAAAAAAAG AACACTCCTT TCTGAGACTT TGCTTAATAC TTGGTGACCT 4380 CACAATCACG TCGGTATGAT TGGGCACCCT TGCCTACTGT AAGAGACCCT AAAACCTTGG 4440 TGCAGTGGTG GGGACCACAA AACAACCAGG GAGGAAGAGA TACATCATTT TTTAGTATTA 4500 AGGACCATCT AAGACAGCTC TATTTTTTTT TTGCCACTTT ATGATTATGT GGTCACACCC 4560 AAGTCACAGA AATAAAAAAC TGACTTTACC GCTGCAATTT TTCTGTTTTC CTCCTTACTA 4620 AATACTGATA CATTACTCCA ATCTATTTTA TAATTATATT TGACATTTTG TTCACATCAA 4680 CTAATGTTCA CCTGTAGAAG AGAACAAATT TCGAATAATC CAGGGAAACC CAAGAGCCTT 4740 ACTGGTCTTC TGTAACTTCC AAGACTGACA GCTTTTTATG TATCAGTGTT TGATAAACAC 4800 AGTCCTTAAC TGAAGGTAAA CCAAAGCATC ACGTTGACAT TAGACCAAAT ACTTTTGATT 4860 CCCAACTACT CGTTTGTTCT TTTTCTCCTT TTGTGCTTTC CCATAGTGAG AATTTTTATA 4920 AAGACTTCTT GCTTCTCTCA CCATCCATCC TTCTCTTTTC TGCCTCTTAC ATGTGAATGT 4980 TGAGCCCACA ATCAACAGTG GTTTTATTTT TTCCTCTACT CAAAGTTAAA ACTGACCAAA 5040 GTTACTGGCT TTTTACTTTG CTAGAACAAC AAACTATCTT ATGTTTACAT ACTGGTTTAC 5100 AATGTTATTT ATGTGCAAAT TGTCAAAATG TAAATTAAAT ATAAATGTTC ATGCTTTACC 5160 AAAA
5165Nucleotide Fasta Sequence
>ENSP00000358092.4|RIZ|Homo sapiens GGGAAGCCAGACGGTTAACACAGACAAAGTGCTGCCGTGACACTCGGCCCTCCAGTGTTGCGGAGAGGCAAGAGCAGCGACCGCGGCACCTGTCCGCCCGGAGCTGGGACGCGGGCGCCCGGGCGGCCGGACGAAGCGAGGAGGGACCGCCGAGGTGCGCGTCTGTGCGGCTCAGCCTGGCGGGGGACGCGGGGAGAATGTGGACTGGGTAGAGATGAACGAGACTTTTCTCAGATGTTGGATATTTGCTTGGAAAAACGTGTGGGTACGACCTTGGCTGCCCCCAAGTGTAACTCCAGCACTGTGAGGTTTCAGGGATTGGCAGAGGGGACCAAGGGGACCATGAAAATGGACATGGAGGATGCGGATATGACTCTGTGGACAGAGGCTGAGTTTGAAGAGAAGTGTACATACATTGTGAACGACCACCCCTGGGATTCTGGTGCTGATGGCGGTACTTCGGTTCAGGCGGAGGCATCCTTACCAAGGAATCTGCTTTTCAAGTATGCCACCAACAGTGAAGAGGTTATTGGAGTGATGAGTAAAGAATACATACCAAAGGGCACACGTTTTGGACCCCTAATAGGTGAAATCTACACCAATGACACAGTTCCTAAGAACGCCAACAGGAAATATTTTTGGAGGATCTATTCCAGAGGGGAGCTTCACCACTTCATTGACGGCTTTAATGAAGAGAAAAGCAACTGGATGCGCTATGTGAATCCAGCACACTCTCCCCGGGAGCAAAACCTGGCTGCGTGTCAGAACGGGATGAACATCTACTTCTACACCATTAAGCCCATCCCTGCCAACCAGGAACTTCTTGTGTGGTATTGTCGGGACTTTGCAGAAAGGCTTCACTACCCTTATCCCGGAGAGCTGACAATGATGAATCTCACACAAACACAGAGCAGTCTAAAGCAACCGAGCACTGAGAAAAATGAACTCTGCCCAAAGAATGTCCCAAAGAGAGAGTACAGCGTGAAAGAAATCCTAAAATTGGACTCCAACCCCTCCAAAGGAAAGGACCTCTACCGTTCTAACATTTCACCCCTCACATCAGAAAAGGACCTCGATGACTTTAGAAGACGTGGGAGCCCCGAAATGCCCTTCTACCCTCGGGTCGTTTACCCCATCCGGGCCCCTCTGCCAGAAGACTTTTTGAAAGCTTCCCTGGCCTACGGGATCGAGAGACCCACGTACATCACTCGCTCCCCCATTCCATCCTCCACCACTCCAAGCCCCTCTGCAAGAAGCAGCCCCGACCAAAGCCTCAAGAGCTCCAGCCCTCACAGCAGCCCTGGGAATACGGTGTCCCCTGTGGGCCCCGGCTCTCAAGAGCACCGGGACTCCTACGCTTACTTGAACGCGTCCTACGGCACGGAAGGTTTGGGCTCCTACCCTGGCTACGCACCCCTGCCCCACCTCCCGCCAGCTTTCATCCCCTCGTACAACGCTCACTACCCCAAGTTCCTCTTGCCCCCCTACGGCATGAATTGTAATGGCCTGAGCGCTGTGAGCAGCATGAATGGCATCAACAACTTTGGCCTCTTCCCGAGGCTGTGCCCTGTCTACAGCAATCTCCTCGGTGGGGGCAGCCTGCCCCACCCCATGCTCAACCCCACTTCTCTCCCGAGCTCGCTGCCCTCAGATGGAGCCCGGAGGTTGCTCCAGCCGGAGCATCCCAGGGAGGTGCTTGTCCCGGCGCCCCACAGTGCCTTCTCCTTTACCGGGGCCGCCGCCAGCATGAAGGACAAGGCCTGTAGCCCCACAAGCGGGTCTCCCACGGCGGGAACAGCCGCCACGGCAGAACATGTGGTGCAGCCCAAAGCTACCTCAGCAGCGATGGCAGCCCCCAGCAGCGACGAAGCCATGAATCTCATTAAAAACAAAAGAAACATGACCGGCTACAAGACCCTTCCCTACCCGCTGAAGAAGCAGAACGGCAAGATCAAGTACGAATGCAACGTTTGCGCCAAGACTTTCGGCCAGCTCTCCAATCTGAAGGTCCACCTGAGAGTGCACAGTGGAGAACGGCCTTTCAAATGTCAGACTTGCAACAAGGGCTTTACTCAGCTCGCCCACCTGCAGAAACACTACCTGGTACACACGGGAGAAAAGCCACATGAATGCCAGGTCTGCCACAAGAGATTTAGCAGCACCAGCAATCTCAAGACCCACCTGCGACTCCATTCTGGAGAGAAACCATACCAATGCAAGGTGTGCCCTGCCAAGTTCACCCAGTTTGTGCACCTGAAACTGCACAAGCGTCTGCACACCCGGGAGCGGCCCCACAAGTGCTCCCAGTGCCACAAGAACTACATCCATCTCTGTAGCCTCAAGGTTCACCTGAAAGGGAACTGCGCTGCGGCCCCGGCGCCTGGGCTGCCCTTGGAAGATCTGACCCGAATCAATGAAGAAATCGAGAAGTTTGACATCAGTGACAATGCTGACCGGCTCGAGGACGTGGAGGATGACATCAGTGTGATCTCTGTAGTGGAGAAGGAAATTCTGGCCGTGGTCAGAAAAGAGAAAGAAGAAACTGGCCTGAAAGTGTCTTTGCAAAGAAACATGGGGAATGGACTCCTCTCCTCAGGGTGCAGCCTTTATGAGTCATCAGATCTACCCCTCATGAAGTTGCCTCCCAGCAACCCACTACCTCTGGTACCTGTAAAGGTCAAACAAGAAACAGTTGAACCAATGGATCCTTAAGATTTTCAGAAAACACTTATTTTGTTTCTTAAGTTATGACTTGGTGAGTCAGGGTGCCTGTAGGAAGTGGCTTGTACATAATCCCAGCTCTGCAAAGCTCTCTCGACAGCAAATGGTTTCCCCTCACCTCTGGAATTAAAGAAGGAACTCCAAAGTTACTGAAATCTCAGGGCATGAACAAGGCAAAGGCCATATATATATATATATATATATCTGTATACATATTATATATACTTATTTACACCTGTGTCTATATATTTGCCCCTGTGTATTTTGAATATTTGTGTGGACATGTTTGCATAGCCTTCCCATTACTAAGACTATTACCTAGTCATAATTATTTTTTCAATGATAATCCTTCATAATTTATTATACAATTTATCATTCAGAAAGCAATAATTAAAAAAGTTTACAATGACTGGAAAGATTCCTTGTAATTTGAGTATAAATGTATTTTTGTCTTGTGGCCATTCTTTGTAGATAATTTCTGCACATCTGTATAAGTACCTAAGATTTAGTTAAACAAATATATGACTTCAGTCAACCTCTCTCTCTAATAATGGTTTGAAAATGAGGTTTGGGTAATTGCCAATGTTGGACAGTTGATGTGTTCATTCCTGGGATCCTATCATTTGAACAGCATTGTACATAACTTGGGGGTATGTGTGCAGGATTACCCAAGAATAACTTAAGTAGAAGAAACAAGAAAGGGAATCTTGTATATTTTTGTTGATAGTTCATGTTTTTCCCCCAGCCACAATTTTACCGGAAGGGTGACAGGAAGGCTTTACCAACCTGTCTCTCCCTCCAAAAGAGCAGAATCCTCCCACCGCCCTGCCCTCCCCACCGAGTCCTGTGGCCATTCAGAGCGGCCACATGACTTTTGCATCCATTGTATTATCAGAAAATGTGAAGAAGAAAAAAATGCCATGTTTTAAAACCACTGCGAAAATTTCCCCAAAGCATAGGTGGCTTTGTGTGTGTGCGATTTGGGGGCTTGAGTCTGGGTGGTGTTTTGTTGTTGGTTTTTGTTGCTTTTTTTTTTTTTTTTTTTTTAATGTCAAAATTGCACAAACATGGTGCTCTACCAGGAAGGATTCGAGGTAGATAGGCTCAGGCCACACTTTAAAAACAAACACACAAACAACAAAAAACGGGTATTCTAGTCATCTTGGGGTAAAAGCGGGTAATGAACATTCCTATCCCCAACACATCAATTGTATTTTTTCTGTAAAACTCAGATTTTCCTCAGTATTTGTGTTTTTACATTTTATGGTTAATTTAATGGAAGATGAAAGGGCATTGCAAAGTTGTTCAACAACAGTTACCTCATTGAGTGTGTCCAGTAGTGCAGGAAATGATGTCTTATCTAATGATTTGCTTCTCTAGAGGAGAAACCGAGTAAATGTGCTCCAGCAAGATAGACTTTGTGTTATTCTATCTTTTATTCTGCTAAGCCCAAAGATTACATGTTGGTGTTCAAAGTGTAGCAAAAAATGATGTATATTTATAAATCTATTTATACCACTATATCATATGTATATATATTTATAACCACTTAAATTGTGAGCCAAGCCATGTAAAAGATCTACTTTTTCTAAGGGCAAAAAAAAAAAAAAAAAAAAAAGAACACTCCTTTCTGAGACTTTGCTTAATACTTGGTGACCTCACAATCACGTCGGTATGATTGGGCACCCTTGCCTACTGTAAGAGACCCTAAAACCTTGGTGCAGTGGTGGGGACCACAAAACAACCAGGGAGGAAGAGATACATCATTTTTTAGTATTAAGGACCATCTAAGACAGCTCTATTTTTTTTTTGCCACTTTATGATTATGTGGTCACACCCAAGTCACAGAAATAAAAAACTGACTTTACCGCTGCAATTTTTCTGTTTTCCTCCTTACTAAATACTGATACATTACTCCAATCTATTTTATAATTATATTTGACATTTTGTTCACATCAACTAATGTTCACCTGTAGAAGAGAACAAATTTCGAATAATCCAGGGAAACCCAAGAGCCTTACTGGTCTTCTGTAACTTCCAAGACTGACAGCTTTTTATGTATCAGTGTTTGATAAACACAGTCCTTAACTGAAGGTAAACCAAAGCATCACGTTGACATTAGACCAAATACTTTTGATTCCCAACTACTCGTTTGTTCTTTTTCTCCTTTTGTGCTTTCCCATAGTGAGAATTTTTATAAAGACTTCTTGCTTCTCTCACCATCCATCCTTCTCTTTTCTGCCTCTTACATGTGAATGTTGAGCCCACAATCAACAGTGGTTTTATTTTTTCCTCTACTCAAAGTTAAAACTGACCAAAGTTACTGGCTTTTTACTTTGCTAGAACAACAAACTATCTTATGTTTACATACTGGTTTACAATGTTATTTATGTGCAAATTGTCAAAATGTAAATTAAATATAAATGTTCATGCTTTACCAAAA
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Sequence Source |
Ensembl |
Keyword |
KW-0002--3D-structure KW-0025--Alternative splicing KW-0181--Complete proteome KW-0963--Cytoplasm KW-0238--DNA-binding KW-1017--Isopeptide bond KW-0479--Metal-binding KW-0489--Methyltransferase KW-0539--Nucleus KW-0621--Polymorphism KW-1185--Reference proteome KW-0677--Repeat KW-0678--Repressor KW-0949--S-adenosyl-L-methionine KW-0804--Transcription KW-0805--Transcription regulation KW-0808--Transferase KW-0832--Ubl conjugation KW-0862--Zinc KW-0863--Zinc-finger --
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Interpro |
IPR016608--PRDM1 IPR001214--SET_dom IPR007087--Znf_C2H2 IPR015880--Znf_C2H2-like IPR013087--Znf_C2H2/integrase_DNA-bd
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PROSITE |
PS50280--SET PS00028--ZINC_FINGER_C2H2_1 PS50157--ZINC_FINGER_C2H2_2
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Pfam |
PF00856--SET PF13912--zf-C2H2_6
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Gene Ontology |
GO:0005737--C:cytoplasm GO:0005654--C:nucleoplasm GO:0046872--F:metal ion binding GO:0008168--F:methyltransferase activity GO:0000978--F:RNA polymerase II core promoter proximal region sequence-specific DNA binding GO:0003700--F:transcription factor activity, sequence-specific DNA binding GO:0001078--F:transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding GO:0035904--P:aorta development GO:0048844--P:artery morphogenesis GO:0045165--P:cell fate commitment GO:0060976--P:coronary vasculature development GO:0042462--P:eye photoreceptor cell development GO:0007281--P:germ cell development GO:0003170--P:heart valve development GO:0060576--P:intestinal epithelial cell development GO:0001893--P:maternal placenta development GO:0001763--P:morphogenesis of a branching structure GO:0030889--P:negative regulation of B cell proliferation GO:0031665--P:negative regulation of lipopolysaccharide-mediated signaling pathway GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter GO:0045579--P:positive regulation of B cell differentiation GO:0010628--P:positive regulation of gene expression GO:0009791--P:post-embryonic development GO:1990654--P:sebum secreting cell proliferation GO:0006351--P:transcription, DNA-templated GO:0060707--P:trophoblast giant cell differentiation GO:0003281--P:ventricular septum development
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Orthology |
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Created Date |
25-Jun-2016 |