WERAM Information


Tag Content
WERAM ID WERAM-Cae-0036
Ensembl Protein ID C35A5.9
Uniprot Accession Q18477; Q18477_CAEEL
Genbank Protein ID NP_505699.3
Protein Name Histone DeAcetylase
Genbank Nucleotide ID NM_073298.3
Gene Name HDA-11;C35A5.9;CELE_C35A5.9
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
WBGene00007953 C35A5.9 C35A5.9
Details
Type Family Domain Substrates AA References (PMIDs)
HDAC Class-IV Hist_deacetyl K 12466527
Status Reviewed
Classification
Type Family E-value Score Start End
HDAC Class-I 7.80e-23 82.1 19 314
Organism Caenorhabditis elegans
NCBI Taxa ID 6239
Functional Description
(View)
Domain Profile
  HDAC Class-I

  class-1.txt   3 vayaydedvgeyhygqkhpmkpkrlsltheLvlnyglskkleivkpkkasaeellkfhseeyieflkkvepenaeelskelkkfnvgedcPvfdglfe 100
++y+ + +v+ + +++ hp ++++ + + + +l + ++v+p+ ++eel+++h +y++ + +++ + + e+ + c + ++l +
C35A5.9 19 IVYHSEYNVTAFGIEHLHPFDSSKWRRVITHLKEMNLITDETLVEPNLPTFEELTRVHDRKYLKSV---RNPIKAAQIVEIPFVGCLPPCIIESKLLH 113
7899************************999*****************************997655...55555556667778888899********* PP
class-1.txt 101 ycqlitGasleaakkLnkkeadiainwaGGlhhakkseasGfcyvnDivlailel..lkkhkrvlyididlhhGDgveeafyttdrvmtvsfhkygee 196
+l +G+++ aa+ + ain GG+hha +s Gfc+ Di +ai +l +k + +d+d h G+g f v+ f ++++
C35A5.9 114 PLRLQAGGTVLAANL-A-LKHGWAINVGGGFHHASHSGGGGFCFYADITMAIFDLfdKKAIANAIVVDLDAHQGNGHARDFADNPNVFV--FDVFNPY 207
*********988764.3.345689*******************************4346789999***********9999999988875..7889**9 PP
class-1.txt 197 ffPgtGdlsdvgaekgkyyavnvPlkdgidDesyekifksviskvieafe...P..eavvlqcGaDslagDrlgefnlsikghae....cvkfvksfn 285
+P ++ ++ ++ vn +d ++++++ k++ + +i++ + P + ++++ G+D l gD+lg +ls + + + ++ ks
C35A5.9 208 VYPHD---REARQFINRAVHVNGHTTD---TSYLSELRKQLAQCLIDREKttpPgfDFIMFNAGTDCLLGDPLGAMKLSPQCIIArdevVFNLAKSKG 299
99976...5556666777778865444...44445555555555554433111433579********************8865322345668999*** PP
class-1.txt 286 lpllvlGGGGYtlrn 300
+p+ ++ GGY++ n
C35A5.9 300 IPICMVTSGGYQKDN 314
***********9987 PP

Protein Sequence
(Fasta)
MAERDKDEIF SLKSYQRPIV YHSEYNVTAF GIEHLHPFDS SKWRRVITHL KEMNLITDET 60
LVEPNLPTFE ELTRVHDRKY LKSVRNPIKA AQIVEIPFVG CLPPCIIESK LLHPLRLQAG 120
GTVLAANLAL KHGWAINVGG GFHHASHSGG GGFCFYADIT MAIFDLFDKK AIANAIVVDL 180
DAHQGNGHAR DFADNPNVFV FDVFNPYVYP HDREARQFIN RAVHVNGHTT DTSYLSELRK 240
QLAQCLIDRE KTTPPGFDFI MFNAGTDCLL GDPLGAMKLS PQCIIARDEV VFNLAKSKGI 300
PICMVTSGGY QKDNALLIAK SIENLQSKNL ISIK 334
Nucleotide Sequence
(Fasta)
CAGTTTCCAC TATTTTCAGA ATTCGTTATC TGTTTTCTGA TAACAAAAAC AAGAAAAACA 60
GAATCTTTAC GACTACTTCT TTATTTATCC GCTCTAACCA CTCATTCTAC GCAGATTTTG 120
AATGGCAGAG CGAGATAAAG ATGAAATCTT TAGTTTAAAA AGTTATCAAC GTCCAATTGT 180
CTATCATTCT GAATATAATG TAACTGCATT TGGAATCGAA CATTTACATC CATTTGATTC 240
TTCGAAATGG AGAAGAGTCA TTACACATTT GAAAGAAATG AATCTGATCA CTGATGAAAC 300
ACTCGTTGAG CCAAATCTAC CGACATTTGA AGAACTCACT AGAGTACATG ATAGAAAATA 360
TCTGAAAAGT GTTCGAAATC CTATTAAAGC AGCACAAATC GTCGAGATTC CATTTGTCGG 420
TTGCCTTCCA CCGTGCATTA TTGAAAGCAA GTTATTGCAT CCACTACGTT TACAAGCCGG 480
TGGAACAGTT TTAGCTGCCA ATTTGGCTCT AAAACATGGT TGGGCGATCA ACGTGGGTGG 540
TGGTTTCCAT CATGCTTCTC ATTCGGGCGG AGGTGGATTC TGTTTTTACG CTGATATCAC 600
CATGGCAATT TTCGATTTGT TTGACAAAAA GGCAATTGCC AACGCGATTG TTGTAGATTT 660
AGATGCTCAT CAGGGAAATG GCCATGCACG AGACTTTGCT GACAATCCGA ATGTGTTTGT 720
ATTTGATGTT TTCAATCCAT ATGTCTATCC ACATGATCGT GAAGCTCGTC AATTTATTAA 780
CAGAGCGGTT CATGTAAATG GTCATACGAC TGATACTTCC TACCTCTCCG AATTACGCAA 840
ACAACTGGCA CAGTGTTTAA TTGATAGAGA GAAAACTACT CCTCCTGGTT TCGATTTCAT 900
TATGTTCAAC GCTGGCACAG ACTGTCTACT TGGTGATCCT CTGGGAGCAA TGAAATTGAG 960
TCCACAGTGC ATAATTGCTC GAGACGAAGT TGTGTTCAAT CTAGCAAAAT CAAAAGGAAT 1020
TCCAATTTGC ATGGTAACCA GTGGAGGGTA TCAGAAGGAC AACGCGCTTC TCATTGCAAA 1080
ATCAATTGAA AATCTCCAGT CAAAGAATCT CATCAGTATC AAATAA 1127
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-1185--Reference proteome
--

Interpro

IPR000286--His_deacetylse
IPR023801--His_deacetylse_dom

PROSITE
Pfam

PF00850--Hist_deacetyl

Gene Ontology

GO:0033558--F:protein deacetylase activity
GO:0006476--P:protein deacetylation

Orthology
WERAM ID Ensembl Protein ID Species Identity E-value Score
WERAM-Pof-0112 ENSPFOP00000009813.1 Poecilia formosa 51 2e-81 300
WERAM-Xim-0081 ENSXMAP00000007517.1 Xiphophorus maculatus 51 1e-80 296
WERAM-Sol-0102 Solyc08g065350.2.1 Solanum lycopersicum 49 3e-78 289
WERAM-Pem-0019 ENSPMAP00000002586.1 Petromyzon marinus 49 1e-77 287
WERAM-Orla-0136 ENSORLP00000016174.1 Oryzias latipes 50 2e-77 286
WERAM-Meg-0057 ENSMGAP00000005254.2 Meleagris gallopavo 50 2e-77 286
WERAM-Mup-0199 ENSMPUP00000017162.1 Mustela putorius furo 50 6e-77 285
WERAM-Sem-0048 EFJ15307 Selaginella moellendorffii 48 6e-77 285
WERAM-Eqc-0015 ENSECAP00000002522.1 Equus caballus 50 6e-77 285
WERAM-Aim-0104 ENSAMEP00000010054.1 Ailuropoda melanoleuca 50 1e-76 283
WERAM-Myl-0189 ENSMLUP00000015766.2 Myotis lucifugus 50 1e-76 283
WERAM-Pes-0146 ENSPSIP00000017189.1 Pelodiscus sinensis 50 1e-76 283
WERAM-Bot-0074 ENSBTAP00000009482.5 Bos taurus 49 1e-76 283
WERAM-Gaga-0055 ENSGALP00000008151.4 Gallus gallus 50 1e-76 283
WERAM-Tut-0131 ENSTTRP00000010611.1 Tursiops truncatus 48 2e-76 283
WERAM-Ptv-0049 ENSPVAP00000005253.1 Pteropus vampyrus 50 2e-76 283
WERAM-Anp-0099 ENSAPLP00000011801.1 Anas platyrhynchos 50 2e-76 283
WERAM-Anc-0120 ENSACAP00000011278.3 Anolis carolinensis 50 4e-76 281
WERAM-Tag-0056 ENSTGUP00000003927.1 Taeniopygia guttata 50 5e-76 281
WERAM-Cap-0083 ENSCPOP00000005971.2 Cavia porcellus 49 1e-75 280
WERAM-Poa-0118 ENSPPYP00000014982.2 Pongo abelii 49 1e-75 280
WERAM-Gog-0090 ENSGGOP00000007570.2 Gorilla gorilla 49 1e-75 280
WERAM-Hos-0174 ENSP00000295757.3 Homo sapiens 49 2e-75 280
WERAM-Gaa-0111 ENSGACP00000014764.1 Gasterosteus aculeatus 49 2e-75 280
WERAM-Loa-0005 ENSLAFP00000000421.3 Loxodonta africana 48 2e-75 279
WERAM-Mam-0008 ENSMMUP00000001824.2 Macaca mulatta 49 2e-75 279
WERAM-Leo-0143 ENSLOCP00000017300.1 Lepisosteus oculatus 49 3e-75 279
WERAM-Paa-0195 ENSPANP00000003035.1 Papio anubis 49 3e-75 279
WERAM-Cis-0041 ENSCSAVP00000009072.1 Ciona savignyi 49 3e-75 279
WERAM-Orc-0095 ENSOCUP00000008476.2 Oryctolagus cuniculus 49 5e-75 278
WERAM-Chs-0115 ENSCSAP00000005710.1 Chlorocebus sabaeus 49 1e-74 277
WERAM-Dio-0089 ENSDORP00000009107.1 Dipodomys ordii 49 2e-74 276
WERAM-Ran-0042 ENSRNOP00000008962.5 Rattus norvegicus 49 2e-74 276
WERAM-Mum-0132 ENSMUSP00000043828.4 Mus musculus 49 3e-74 275
WERAM-Ocp-0102 ENSOPRP00000009462.1 Ochotona princeps 48 5e-74 275
WERAM-Otg-0083 ENSOGAP00000006490.2 Otolemur garnettii 48 9e-74 274
WERAM-Thc-0103 EOY29884 Theobroma cacao 47 4e-73 272
WERAM-Bro-0132 Bo7g095520.1 Brassica oleracea 44 4e-73 271
WERAM-Orgl-0063 OGLUM06G20210.1 Oryza glumaepatula 45 8e-73 271
WERAM-Sob-0134 Sb10g022550.1 Sorghum bicolor 45 9e-73 271
WERAM-Php-0113 PP1S53_217V6.1 Physcomitrella patens 47 9e-73 271
WERAM-Orn-0036 ENSONIP00000004088.1 Oreochromis niloticus 49 1e-72 270
WERAM-Orr-0066 ORUFI06G20130.1 Oryza rufipogon 45 1e-72 270
WERAM-Ors-0058 OS06T0571100-01 Oryza sativa 45 1e-72 270
WERAM-Orni-0064 ONIVA06G22840.1 Oryza nivara 45 1e-72 270
WERAM-Ori-0066 BGIOSGA021002-PA Oryza indica 45 1e-72 270
WERAM-Org-0062 ORGLA06G0157900.1 Oryza glaberrima 45 1e-72 270
WERAM-Orb-0065 OBART06G18360.1 Oryza barthii 45 1e-72 270
WERAM-Fec-0086 ENSFCAP00000006953.3 Felis catus 49 1e-72 270
WERAM-Pot-0080 POPTR_0006s24640.1 Populus trichocarpa 44 1e-72 270
WERAM-Caf-0054 ENSCAFP00000006551.3 Canis familiaris 49 2e-72 270
WERAM-Brr-0052 Bra009877.1-P Brassica rapa 44 3e-72 269
WERAM-Met-0014 AES59273 Medicago truncatula 46 3e-72 269
WERAM-Sah-0048 ENSSHAP00000005466.1 Sarcophilus harrisii 47 6e-72 268
WERAM-Glm-0229 GLYMA17G34770.1 Glycine max 45 7e-72 268
WERAM-Sei-0028 Si006784m Setaria italica 46 7e-72 268
WERAM-Viv-0015 VIT_04s0008g00910.t01 Vitis vinifera 47 2e-71 266
WERAM-Zem-0011 GRMZM2G008425_P01 Zea mays 46 4e-71 265
WERAM-Mod-0065 ENSMODP00000010728.2 Monodelphis domestica 44 4e-71 265
WERAM-Nol-0049 ENSNLEP00000005908.2 Nomascus leucogenys 48 5e-71 265
WERAM-Mae-0056 ENSMEUP00000005580.1 Macropus eugenii 47 8e-71 264
WERAM-Tra-0321 Traes_7DL_86EEFA04E.2 Triticum aestivum 43 5e-70 261
WERAM-Arl-0095 fgenesh2_kg.6__ 2585__ AT5G26040.2 Arabidopsis lyrata 45 1e-69 260
WERAM-Art-0129 AT5G26040.2 Arabidopsis thaliana 45 3e-69 259
WERAM-Sus-0082 ENSSSCP00000012372.2 Sus scrofa 47 3e-69 259
WERAM-Brd-0021 BRADI1G37510.1 Brachypodium distachyon 44 4e-69 258
WERAM-Dar-0190 ENSDARP00000109681.2 Danio rerio 46 5e-68 255
WERAM-Lac-0082 ENSLACP00000010626.1 Latimeria chalumnae 47 5e-66 248
WERAM-Mua-0015 GSMUA_Achr10P28050_001 Musa acuminata 43 5e-65 245
WERAM-Tru-0023 TRIUR3_12206-P1 Triticum urartu 45 2e-64 243
WERAM-Fia-0001 ENSFALP00000000041.1 Ficedula albicollis 48 6e-64 241
WERAM-Orm-0062 OMERI06G19350.1 Oryza meridionalis 43 2e-63 239
WERAM-Drm-0083 FBpp0084109 Drosophila melanogaster 43 2e-63 239
WERAM-Gam-0017 ENSGMOP00000001513.1 Gadus morhua 44 4e-63 239
WERAM-Orbr-0073 OB06G26590.1 Oryza brachyantha 41 2e-62 236
WERAM-Asm-0175 ENSAMXP00000017267.1 Astyanax mexicanus 50 6e-60 228
WERAM-Lep-0065 LPERR06G15640.1 Leersia perrieri 42 3e-58 222
WERAM-Cii-0063 ENSCINP00000027979.2 Ciona intestinalis 47 9e-58 221
WERAM-Prp-0064 EMJ26901 Prunus persica 45 1e-57 220
WERAM-Aet-0055 EMT26973 Aegilops tauschii 38 3e-57 219
WERAM-Mim-0127 ENSMICP00000012962.1 Microcebus murinus 43 3e-57 219
WERAM-Sot-0090 PGSC0003DMT400076986 Solanum tuberosum 52 3e-56 216
WERAM-Ova-0011 ENSOARP00000001712.1 Ovis aries 43 4e-56 215
WERAM-Ict-0088 ENSSTOP00000009419.2 Ictidomys tridecemlineatus 48 2e-55 213
WERAM-Dan-0117 ENSDNOP00000014714.2 Dasypus novemcinctus 49 5e-54 208
WERAM-Prc-0001 ENSPCAP00000000121.1 Procavia capensis 40 1e-52 204
WERAM-Orp-0063 OPUNC06G17220.1 Oryza punctata 46 1e-49 194
WERAM-Chr-0007 EDP00102 Chlamydomonas reinhardtii 38 3e-49 192
WERAM-Hov-0085 MLOC_6441.1 Hordeum vulgare 42 2e-46 183
WERAM-Pat-0124 ENSPTRP00000025262.3 Pan troglodytes 50 1e-45 180
WERAM-Ora-0107 ENSOANP00000020314.1 Ornithorhynchus anatinus 46 5e-32 135
WERAM-Orl-0079 KN539689.1_FGP004 Oryza longistaminata 37 3e-30 129
WERAM-Caj-0177 ENSCJAP00000031023.1 Callithrix jacchus 42 1e-26 117
WERAM-Amt-0062 ERN16364 Amborella trichopoda 47 1e-24 111
WERAM-Ect-0025 ENSETEP00000001831.1 Echinops telfairi 37 2e-24 110
WERAM-Tub-0108 ENSTBEP00000012162.1 Tupaia belangeri 44 4e-24 109
WERAM-Osl-0038 ABO99879 Ostreococcus lucimarinus 28 4e-22 102
WERAM-Tar-0078 ENSTRUP00000015330.1 Takifugu rubripes 32 2e-21 100
WERAM-Chh-0019 ENSCHOP00000001858.1 Choloepus hoffmanni 37 4e-20 96.3
WERAM-Cym-0025 CMQ158CT Cyanidioschyzon merolae 32 9e-10 62.0
WERAM-Lem-0025 CBX91242 Leptosphaeria maculans 29 5e-09 59.3
WERAM-Asfu-0012 CADAFUAP00003362 Aspergillus fumigatus 26 8e-09 58.5
WERAM-Kll-0020 CAG99415 Kluyveromyces lactis 23 7e-08 55.5
WERAM-Asc-0036 CADACLAP00008360 Aspergillus clavatus 25 9e-08 55.1
WERAM-Scs-0017 EDO01763 Sclerotinia sclerotiorum 29 2e-07 53.9
WERAM-Phn-0003 SNOT_00459 Phaeosphaeria nodorum 27 7e-07 52.4
WERAM-Ten-0019 ENSTNIP00000004593.1 Tetraodon nigroviridis 24 7e-07 52.4
WERAM-Scj-0027 EEB08472 Schizosaccharomyces japonicus 24 1e-06 51.6
WERAM-Asg-0026 AAS53543 Ashbya gossypii 28 3e-06 50.4
WERAM-Usm-0012 UM02102P0 Ustilago maydis 23 3e-06 50.1
Created Date 25-Jun-2016