WERAM Information

Tag Content
WERAM ID WERAM-Art-0046
Ensembl Protein ID AT2G27840.1
Uniprot Accession Q9M4T3; HDT4_ARATH; Q0WN36; Q9ZUY5
Genbank Protein ID NP_565661.2; NP_850109.1
Protein Name Histone deacetylase HDT4
Genbank Nucleotide ID NM_128344.3; NM_179778.1
Gene Name HDT4;HD2D;HDA13;At2g27840;F15K20.6
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
AT2G27840 AT2G27840.1 AT2G27840.1
Details
Type Family Domain Substrates AA References (PMIDs)
HDAC HD2 H2A; H2B; H3; H4 K 26689639
Status Reviewed
Classification
Type Family E-value Score Start End
HDAC HD2 9.00e-78 286
Organism Arabidopsis thaliana
NCBI Taxa ID 3702
Functional Description
(View)		 Probably mediates the deacetylation of lysine residues lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.
Domain Profile
  HDAC HD2
Query: 1   MEFWGIEIKPGKPFKVIQKDGFMVHASQVTLGDVEKVKKDETFAVYVKIGDDENGFMIGN 60
           MEFWGIEIKPGKPFKVIQKDGFMVHASQVTLGDVEKVKKDETFAVYVKIGDDENGFMIGN
Sbjct: 1   MEFWGIEIKPGKPFKVIQKDGFMVHASQVTLGDVEKVKKDETFAVYVKIGDDENGFMIGN 60
Query: 61  LSQKFPQFSIDLYLGHEFEISHNSTSSVYLIGYRTFDAFXXXXXXXXXXXXXXXYMEQQI 120
           LSQKFPQFSIDLYLGHEFEISHNSTSSVYLIGYRTFDAF               YMEQQI
Sbjct: 61  LSQKFPQFSIDLYLGHEFEISHNSTSSVYLIGYRTFDAFDELDEEIDSDSELDEYMEQQI 120
Query: 121 AALPQNEINPXXXXXXXXXXXXXXXXXXXXXXXXXXXXAPLKVAPPSKKMPNGAFEIAXX 180
           AALPQNEINP                            APLKVAPPSKKMPNGAFEIA  
Sbjct: 121 AALPQNEINPEEDDESDSDEMGLDEDDDSSDEEDVEAEAPLKVAPPSKKMPNGAFEIAKG 180
Query: 181 XXXXXXXXXXXRCPFPCGPSCKK 203
                      RCPFPCGPSCKK
Sbjct: 181 GKKNKSSGGKKRCPFPCGPSCKK 203
Protein Sequence
(Fasta)		MEFWGIEIKP GKPFKVIQKD GFMVHASQVT LGDVEKVKKD ETFAVYVKIG DDENGFMIGN 60
LSQKFPQFSI DLYLGHEFEI SHNSTSSVYL IGYRTFDAFD ELDEEIDSDS ELDEYMEQQI 120
AALPQNEINP EEDDESDSDE MGLDEDDDSS DEEDVEAEAP LKVAPPSKKM PNGAFEIAKG 180
GKKNKSSGGK KRCPFPCGPS CKK 203
Nucleotide Sequence
(Fasta)		AAGCCGCTCC ATTATTTTTG TTTGTTTGAA ACAAACTCTA AAACCCTAAA TTCTTCTTCT 60
CAAGCAGCCA CATCTTCCTC TTTCACTAGC TATGGAGTTT TGGGGTATCG AGATTAAGCC 120
AGGGAAGCCA TTTAAGGTGA TACAAAAAGA TGGATTCATG GTCCATGCCT CTCAGGTTAC 180
CCTTGGTGAC GTTGAGAAGG TTAAAAAAGA TGAGACTTTT GCCGTTTATG TGAAGATTGG 240
TGATGATGAG AATGGGTTTA TGATTGGAAA TCTCTCACAG AAGTTTCCTC AATTTTCTAT 300
TGATCTCTAC TTAGGGCACG AGTTTGAGAT TTCTCACAAC AGTACAAGCA GTGTCTATCT 360
TATTGGTTAC AGGACCTTTG ATGCTTTTGA CGAACTGGAT GAGGAGATTG ATTCTGATTC 420
TGAGTTAGAT GAATATATGG AACAACAAAT TGCTGCTTTG CCTCAAAATG AGATCAATCC 480
TGAAGAAGAT GATGAATCCG ACTCAGATGA GATGGGTTTG GACGAGGATG ATGACTCTTC 540
AGATGAAGAA GATGTAGAGG CTGAAGCACC TTTAAAGGTG GCTCCTCCGA GCAAAAAGAT 600
GCCAAATGGT GCATTTGAGA TAGCTAAAGG TGGAAAGAAG AACAAGTCAT CAGGAGGGAA 660
GAAGAGATGC CCATTCCCTT GTGGTCCCTC TTGCAAAAAG TAGAAGATAT TTGCACACCA 720
AGTCACATTT TTCCAATAGA AATTTTTACT TGACTGTATT GGTGAATCGT TGAGTGACTT 780
ATGAGGCTTT TGGCATCTTA AAATTTTTGG ATTATTATAA TATATGTTAT GTTGTCATTT 840
TGGAGTGTTA ATGGGTTTAA ATGAAATATG ATTTTTGCTC 881
Sequence Source Ensembl
Keyword

KW-0025--Alternative splicing
KW-0156--Chromatin regulator
KW-0181--Complete proteome
KW-0217--Developmental protein
KW-0378--Hydrolase
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0678--Repressor
KW-0804--Transcription
KW-0805--Transcription regulation
--
Interpro
PROSITE
Pfam
Gene Ontology

GO:0005730--C:nucleolus
GO:0016787--F:hydrolase activity
GO:0016568--P:chromatin modification
GO:0006355--P:regulation of transcription, DNA-templated
GO:0010162--P:seed dormancy process
GO:0006351--P:transcription, DNA-templated
Orthology
WERAM ID Ensembl Protein ID Species Identity E-value Score
WERAM-Arl-0035 fgenesh1_pm.C_scaffold_4000660 Arabidopsis lyrata 64 2e-51 199
WERAM-Brr-0167 Bra034373.1-P Brassica rapa 43 1e-27 120
WERAM-Bro-0080 Bo4g164870.1 Brassica oleracea 57 8e-26 114
WERAM-Viv-0052 VIT_08s0007g03940.t01 Vitis vinifera 43 4e-18 88.2
WERAM-Tru-0046 TRIUR3_21067-P1 Triticum urartu 50 6e-17 84.7
WERAM-Aet-0097 EMT09079 Aegilops tauschii 50 7e-17 84.3
WERAM-Thc-0115 EOY33573 Theobroma cacao 44 8e-17 84.0
WERAM-Pot-0048 POPTR_0004s20020.1 Populus trichocarpa 46 2e-16 83.2
WERAM-Hov-0097 MLOC_70585.1 Hordeum vulgare 46 4e-16 81.6
WERAM-Met-0051 KEH38943 Medicago truncatula 42 8e-16 80.9
WERAM-Prp-0078 EMJ06874 Prunus persica 43 1e-15 80.1
WERAM-Zem-0062 GRMZM2G100146_P01 Zea mays 45 1e-15 79.7
WERAM-Sot-0008 PGSC0003DMT400006927 Solanum tuberosum 41 2e-15 79.3
WERAM-Sob-0127 Sb09g026730.1 Sorghum bicolor 46 2e-15 79.3
WERAM-Orni-0013 ONIVA01G46280.1 Oryza nivara 49 3e-15 79.0
WERAM-Orb-0013 OBART01G41240.1 Oryza barthii 49 3e-15 79.0
WERAM-Orr-0013 ORUFI01G44570.1 Oryza rufipogon 49 3e-15 79.0
WERAM-Sol-0107 Solyc09g009030.2.1 Solanum lycopersicum 40 7e-15 77.8
WERAM-Glm-0023 GLYMA03G34850.3 Glycine max 44 2e-14 76.3
WERAM-Sei-0085 Si022778m Setaria italica 43 2e-14 76.3
WERAM-Ors-0052 OS05T0597100-01 Oryza sativa 45 3e-14 75.5
WERAM-Ori-0055 BGIOSGA017430-PA Oryza indica 45 3e-14 75.5
WERAM-Orbr-0066 OB05G35770.1 Oryza brachyantha 45 4e-14 75.1
WERAM-Mua-0063 GSMUA_Achr3P22840_001 Musa acuminata 43 2e-13 72.8
WERAM-Lep-0059 LPERR05G23920.1 Leersia perrieri 44 1e-12 70.1
WERAM-Php-0037 PP1S183_93V6.3 Physcomitrella patens 41 2e-12 69.3
WERAM-Tra-0342 TRAES3BF048700110CFD_t1 Triticum aestivum 42 4e-12 68.6
WERAM-Orp-0054 OPUNC05G25830.1 Oryza punctata 43 5e-12 68.2
WERAM-Orl-0054 KN539082.1_FGP007 Oryza longistaminata 42 9e-10 60.5
WERAM-Sem-0061 EFJ07202 Selaginella moellendorffii 33 1e-09 60.1
WERAM-Brd-0043 BRADI2G14120.1 Brachypodium distachyon 42 4e-09 58.5
WERAM-Org-0014 ORGLA01G0351500.1 Oryza glaberrima 35 4e-08 55.1
Created Date 25-Jun-2016