Setaria italica      HDAC      Class-I

※ Class-I family introduction

    Class-I: Class I HDACs share homology with the yeast Rpd3. This class includes HDACs 1, 2, 3, and 8, and its members are expressed ubiquitously in humans. Members 1, 2, and 3 are found in multi-protein repressor complexes in the nucleus, where they regulate gene expression. HDAC8 is found in both the nucleus and cytoplasm, and while it has not been found in any multi-protein complexes, it has been described to be involved in transcriptional repression. (1)

Reference
1. Koeneke, E., Witt, O., & Oehme, I.HDAC Family Members Intertwined in the Regulation of Autophagy: A Druggable Vulnerability in Aggressive Tumor Entities. Cells.2015;4(2):135-168. PMID: 25915736.



There are 12 genes.  Reviewed (0 or Unreviewed (12

No.StatusWERAM IDGene/Alias Name
1
WERAM-Sei-0016
SETIT_003826mg
2
WERAM-Sei-0017
SETIT_004835mg
3
WERAM-Sei-0026
SETIT_006243mg
4
WERAM-Sei-0028
SETIT_006784mg
5
WERAM-Sei-0035
SETIT_010167mg
6
WERAM-Sei-0036
SETIT_010171mg
7
WERAM-Sei-0051
SETIT_013709mg
8
WERAM-Sei-0069
SETIT_016908mg
9
WERAM-Sei-0070
SETIT_017398mg
10
WERAM-Sei-0083
SETIT_022311mg
11
WERAM-Sei-0109
SETIT_029091mg
12
WERAM-Sei-0111
SETIT_029194mg