WERAM Information

Tag Content
WERAM ID WERAM-Art-0125
Ensembl Protein ID AT5G20510.1
Uniprot Accession Q5XEM9; ALFL5_ARATH
Genbank Protein ID NP_197551.2
Protein Name PHD finger protein ALFIN-LIKE 5
Genbank Nucleotide ID NM_122058.3
Gene Name ALFL5;AL5At5g20510;F7C8.100
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
AT5G20510 AT5G20510.1 AT5G20510.1
Details
Type Family Domain Substrates AA References (PMIDs)
Me_Reader PHD PHD-type H3K4me3/2 K 19154204
Status Reviewed
Classification
Type Family E-value Score Start End
Me_Reader PHD 4.90e-12 46.6 205 255
Organism Arabidopsis thaliana
NCBI Taxa ID 3702
Functional Description
(View)		 Histone-binding component that specifically recognizes H3 tails trimethylated on 'Lys-4' (H3K4me3), which mark transcription start sites of virtually all active genes.
Domain Profile
  Me_Reader PHD
      PHD.txt   2 tiClvCgkddegekemvqCdeCddwfHlkCvklplsslpegkswyCpsCke 52 
                  t+C +Cg++++ ++++++Cd C++wfH++Cvk++  +++  k++ Cp+C +
  AT5G20510.1 205 TLCGACGDNYASDEFWICCDMCEKWFHGECVKITPARAEHIKHYKCPTCSN 255
                  78*****9999999********************666664479******86 PP
Protein Sequence
(Fasta)		MEGGTAHYSP RTVEEVFRDF KGRRAGIIQA LTTDVEDFFQ QCDPEKQNLC LYGFPNEVWE 60
VNLPAEEVPP ELPEPALGIN FARDGMQERN WLSLVAVHSD AWLLSVSFYF GSRFGFDRAD 120
RKRLFSMINE VPTVYEVVTG NAEKQTKEMP SSANQNGNRS KSNSKMRGLE SKSSKTIHAK 180
DEEEGLELEE GEEEEDEDED EHGETLCGAC GDNYASDEFW ICCDMCEKWF HGECVKITPA 240
RAEHIKHYKC PTCSNKRARP
Nucleotide Sequence
(Fasta)		AGAAAAAAAA AAGAAGCAAA CCTCACTGTT CTTTCATCGT TTCCGAGAGA GGAGAGACGG 60
ACATGGAAGG AGGAACTGCG CACTACAGCC CTCGAACTGT CGAAGAAGTC TTTCGAGATT 120
TTAAGGGCCG TCGAGCTGGC ATCATCCAAG CTCTCACCAC TGATGTGGAA GATTTTTTCC 180
AGCAATGCGA CCCTGAGAAG CAGAATCTCT GCTTGTATGG ATTCCCAAAT GAAGTGTGGG 240
AAGTTAACTT ACCAGCTGAA GAAGTGCCTC CTGAGCTTCC CGAACCTGCA CTCGGCATTA 300
ACTTTGCCAG AGATGGGATG CAGGAAAGAA ACTGGCTTTC TCTCGTTGCT GTCCACAGTG 360
ATGCGTGGTT ACTTTCTGTG TCTTTTTACT TTGGTTCAAG ATTTGGTTTC GATAGAGCTG 420
ACAGGAAGCG CTTGTTTAGT ATGATAAATG AGGTTCCTAC TGTATATGAA GTTGTAACTG 480
GAAATGCAGA GAAGCAAACA AAGGAAATGC CCTCTTCAGC AAATCAAAAT GGCAACAGAT 540
CCAAGTCAAA TTCAAAAATG AGAGGTTTAG AAAGTAAAAG TTCAAAGACG ATACATGCCA 600
AGGATGAGGA AGAAGGATTA GAGTTAGAAG AAGGGGAAGA GGAAGAGGAT GAGGATGAAG 660
ACGAACACGG TGAAACCCTA TGTGGAGCAT GTGGAGATAA CTATGCTTCT GATGAATTCT 720
GGATTTGCTG TGACATGTGC GAGAAATGGT TCCACGGGGA GTGTGTGAAG ATCACTCCAG 780
CTAGAGCGGA GCATATCAAG CATTACAAGT GCCCTACTTG CAGCAACAAA AGAGCACGAC 840
CCTAGATGTT TTATTTCCAC TAATCTTAGC TACTATCTAT TTTGTTTTAT TTCCACTAGT 900
CTTAGCTACT CTCTATTTAT CCCCCAAACA GTACAATGCA CTTAAAGTTT GTGTGTTGTT 960
CAGATAAGTT ATTTGTAGCA TGTCCAGATT TGATTCCTCA ACCCAATTTG TATAACTCAG 1020
AAT 1024
Sequence Source Ensembl
Keyword

KW-0007--Acetylation
KW-0156--Chromatin regulator
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0804--Transcription
KW-0805--Transcription regulation
KW-0862--Zinc
KW-0863--Zinc-finger
--
Interpro

IPR021998--Alfin
IPR019786--Zinc_finger_PHD-type_CS
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD
PROSITE

PS01359--ZF_PHD_1
PS50016--ZF_PHD_2
Pfam

PF12165--DUF3594
PF00628--PHD
Gene Ontology

GO:0005634--C:nucleus
GO:0003677--F:DNA binding
GO:0003714--F:transcription corepressor activity
GO:0008270--F:zinc ion binding
GO:0016568--P:chromatin modification
GO:1903507--P:negative regulation of nucleic acid-templated transcription
GO:0006355--P:regulation of transcription, DNA-templated
GO:0009651--P:response to salt stress
GO:0009414--P:response to water deprivation
GO:0006351--P:transcription, DNA-templated
Orthology
WERAM ID Ensembl Protein ID Species Identity E-value Score
WERAM-Arl-0138 scaffold_602145.1 Arabidopsis lyrata 92 2e-116 415
WERAM-Brr-0102 Bra020107.1-P Brassica rapa 83 2e-104 375
WERAM-Bro-0027 Bo2g021880.1 Brassica oleracea 79 1e-100 363
WERAM-Pot-0079 POPTR_0006s23990.1 Populus trichocarpa 77 1e-98 356
WERAM-Prp-0082 EMJ27202 Prunus persica 76 5e-98 354
WERAM-Viv-0068 VIT_11s0016g01500.t01 Vitis vinifera 76 1e-94 343
WERAM-Glm-0158 GLYMA13G16740.1 Glycine max 75 3e-94 341
WERAM-Amt-0032 ERN11177 Amborella trichopoda 73 7e-94 340
WERAM-Thc-0077 EOY27191 Theobroma cacao 77 4e-93 338
WERAM-Mua-0131 GSMUA_Achr8P30680_001 Musa acuminata 72 1e-92 336
WERAM-Met-0044 KEH37528 Medicago truncatula 68 1e-89 327
WERAM-Sol-0143 Solyc12g096040.1.1 Solanum lycopersicum 70 4e-88 321
WERAM-Sot-0055 PGSC0003DMT400047018 Solanum tuberosum 70 8e-87 317
WERAM-Sei-0118 Si030765m Setaria italica 65 5e-86 314
WERAM-Hov-0063 MLOC_56433.1 Hordeum vulgare 65 2e-84 308
WERAM-Orbr-0121 OB11G16440.1 Oryza brachyantha 68 1e-83 306
WERAM-Lep-0110 LPERR11G07220.1 Leersia perrieri 67 2e-83 306
WERAM-Zem-0014 GRMZM2G016817_P02 Zea mays 64 4e-83 304
WERAM-Sob-0124 Sb09g020610.1 Sorghum bicolor 65 1e-82 303
WERAM-Ors-0103 OS11T0244800-01 Oryza sativa 67 2e-82 302
WERAM-Orr-0116 ORUFI11G08380.1 Oryza rufipogon 67 2e-82 302
WERAM-Orni-0115 ONIVA11G08290.1 Oryza nivara 67 2e-82 302
WERAM-Orm-0100 OMERI11G06990.1 Oryza meridionalis 67 2e-82 302
WERAM-Ori-0116 BGIOSGA034217-PA Oryza indica 67 2e-82 302
WERAM-Orgl-0111 OGLUM11G07920.1 Oryza glumaepatula 67 2e-82 302
WERAM-Org-0108 ORGLA11G0071500.1 Oryza glaberrima 67 2e-82 302
WERAM-Orb-0115 OBART11G08090.1 Oryza barthii 67 2e-82 302
WERAM-Brd-0046 BRADI2G25120.1 Brachypodium distachyon 65 9e-82 300
WERAM-Php-0063 PP1S262_27V6.1 Physcomitrella patens 63 9e-82 300
WERAM-Orp-0107 OPUNC11G07880.1 Oryza punctata 67 1e-81 300
WERAM-Aet-0106 EMT19247 Aegilops tauschii 64 4e-79 291
WERAM-Tra-0074 Traes_2BS_9C7CA760D.1 Triticum aestivum 65 2e-78 289
WERAM-Sem-0147 EFJ25244 Selaginella moellendorffii 63 2e-75 279
WERAM-Orl-0063 KN539254.1_FGP005 Oryza longistaminata 67 6e-73 271
Created Date 25-Jun-2016