| Tag |
Content |
| WERAM ID |
WERAM-Drm-0083 |
| Ensembl Protein ID |
FBpp0084109 |
| Uniprot Accession |
Q9VC26; Q9VC26_DROME
|
| Genbank Protein ID |
NP_001247296.1; NP_733048.1
|
| Protein Name |
Histone deacetylase 11, isoform A |
| Genbank Nucleotide ID |
NM_001260367.1; NM_170173.3
|
| Gene Name |
HDAC11;HdacX;HdacX-RA;CG31119;Dmel_CG31119 |
| Ensembl Information |
|
| Details |
| Type |
Family |
Domain |
Substrates |
AA |
References (PMIDs) |
| HDAC |
Class-IV |
Hist_deacetyl |
H2A; H2B; H3; H4 |
K |
21170302
|
|
| Status |
Reviewed |
| Classification |
| Type |
Family |
E-value |
Score |
Start |
End |
| HDAC |
Class-IV |
3.10e-148 |
493.4 |
47 |
333 |
| HDAC |
Class-I |
6.40e-20 |
72.5 |
51 |
323 |
|
| Organism |
Drosophila melanogaster |
| NCBI Taxa ID |
7227 |
Functional Description
(View) |
|
| Domain Profile |
HDAC Class-IV
class-4.txt 1 leklhpfdaskwkkvikflkeeklledealveareaskedllvvhtrkylkslksslkvatiteiplvaflpnflvqrkvlrplrlqagGtilaakla 98
le+lhpfda+k+k+++k+l+++ +l+d++++e++e++k++l+++htr+ylksl++s++va+i+e+pl+af+pn+++qr++lrp+r+qa+G+ila+kla
FBpp0084109 47 LERLHPFDAAKGKHIHKLLCAQLQLDDGSFYEPTELTKDQLRRIHTREYLKSLRWSMNVACIAEVPLMAFVPNRYIQRSYLRPMRFQAAGSILAGKLA 144
79************************************************************************************************ PP
class-4.txt 99 verGwainvGGGfhhcsserGGGfcayaditlaikflfer..lkaisrviiidldahqGnGherdfaddkrvyildvynreiypkdrvakeairrkve 194
+++Gwain+GGGfhhc+s+rGGGfc+yadi+l+i++lfe+ ++ ++r++i+dldahqGnGherdf++ ++vyi+d+yn+++yp+d+vake+ir++ve
FBpp0084109 145 LDYGWAINLGGGFHHCCSYRGGGFCPYADISLLIVRLFEQepFR-VRRIMIVDLDAHQGNGHERDFNNVAAVYIFDMYNAFVYPRDHVAKESIRCAVE 241
***************************************98788.***************************************************** PP
class-4.txt 195 lesgtedeeylekleralkkslqefepdlvvynaGtdvleGdrlGalkispegivkrdevvfrlvrakdipivmvtsGGyqkrsarviadsi 286
l+++ted +yl++l+r+l++sl+ef+pd+vvynaGtdvleGd+lG+l+is+eg+++rd++vf+++ra +ip+vm++sGGy+k+sa+vi+dsi
FBpp0084109 242 LRNYTEDGFYLRQLKRCLMQSLAEFRPDMVVYNAGTDVLEGDPLGNLAISAEGVIERDRLVFSTFRALGIPVVMLLSGGYLKASAGVITDSI 333
*******************************************************************************************9 PP
HDAC Class-I
class-1.txt 20 hpmkpkrlsltheLvlnyglskkleivkpkkasaeellkfhseeyieflkkvepenaeelskelkkfnvgedcPvfdglfeycqlitGasleaakkLn 117
hp + + +h+L+++ + ++++p++ ++++l + h+ ey++ l+ + + + e+ + + + + + +s+ a kL
FBpp0084109 51 HPFDAAKGKHIHKLLCAQLQLDDGSFYEPTELTKDQLRRIHTREYLKSLRWSMNV---ACIAEVPLMAFVPNRYIQRSYLRPMRFQAAGSILA-GKLA 144
6777777778888888877778888899999999999999999998888754322...23333333333444455555555555555555543.3343 PP
class-1.txt 118 kkeadiainwaGGlhhakkseasGfcyvnDivlailellk....khkrvlyididlhhGDgveeafyttdrvmtvsfhkygeeffPgtGdlsdvgaek 211
+ ain GG+hh + Gfc Di l i++l +r++ +d+d h G+g e f++ v f y+ +P d a++
FBpp0084109 145 L-DYGWAINLGGGFHHCCSYRGGGFCPYADISLLIVRLFEqepfRVRRIMIVDLDAHQGNGHERDFNNVAAVYI--FDMYNAFVYPR-----DHVAKE 234
2.45679*******************************984444468*******************99888765..67788856664.....444444 PP
class-1.txt 212 gkyyavnvPlkdgidDesyekifksviskvieafePeavvlqcGaDslagDrlgefnlsikghae....cvkfvksfnlpllvlGGGGYtl 298
+ v l++ +D y + +k+ + + + f+P++vv + G+D l gD+lg+ +s +g e + + ++ +p+++l GGY +
FBpp0084109 235 S--IRCAVELRNYTEDGFYLRQLKRCLMQSLAEFRPDMVVYNAGTDVLEGDPLGNLAISAEGVIErdrlVFSTFRALGIPVVMLLSGGYLK 323
4..345689********9999999999999999*****************************8764544567778899***********76 PP
|
Protein Sequence
(Fasta) | MKRLTERVHH EEQESEEVVW VKRDDARSAG KLPIVFSRNY AVRFGGLERL HPFDAAKGKH 60
IHKLLCAQLQ LDDGSFYEPT ELTKDQLRRI HTREYLKSLR WSMNVACIAE VPLMAFVPNR 120
YIQRSYLRPM RFQAAGSILA GKLALDYGWA INLGGGFHHC CSYRGGGFCP YADISLLIVR 180
LFEQEPFRVR RIMIVDLDAH QGNGHERDFN NVAAVYIFDM YNAFVYPRDH VAKESIRCAV 240
ELRNYTEDGF YLRQLKRCLM QSLAEFRPDM VVYNAGTDVL EGDPLGNLAI SAEGVIERDR 300
LVFSTFRALG IPVVMLLSGG YLKASAGVIT DSIVNLRLQG LLN 343Protein Fasta Sequence
>FBpp0084109|HDAC11;HdacX;HdacX-RA;CG31119;Dmel_CG31119|Drosophila melanogaster
MKRLTERVHHEEQESEEVVWVKRDDARSAGKLPIVFSRNYAVRFGGLERLHPFDAAKGKHIHKLLCAQLQLDDGSFYEPTELTKDQLRRIHTREYLKSLRWSMNVACIAEVPLMAFVPNRYIQRSYLRPMRFQAAGSILAGKLALDYGWAINLGGGFHHCCSYRGGGFCPYADISLLIVRLFEQEPFRVRRIMIVDLDAHQGNGHERDFNNVAAVYIFDMYNAFVYPRDHVAKESIRCAVELRNYTEDGFYLRQLKRCLMQSLAEFRPDMVVYNAGTDVLEGDPLGNLAISAEGVIERDRLVFSTFRALGIPVVMLLSGGYLKASAGVITDSIVNLRLQGLLN |
Nucleotide Sequence
(Fasta) | CCAATTCAAC TGGTGTCGGA CAGATGTAAT CCACGCCTAA ATTGAACCAC AAAATGAAGC 60
GCCTGACTGA GCGAGTGCAC CACGAGGAGC AGGAGTCCGA GGAGGTTGTC TGGGTTAAGC 120
GGGATGACGC ACGCTCCGCC GGCAAACTGC CCATCGTGTT CTCAAGGAAC TATGCGGTTC 180
GCTTCGGTGG CCTTGAACGC CTACATCCCT TCGATGCGGC CAAGGGCAAG CACATTCACA 240
AGCTCCTGTG CGCCCAACTG CAGCTCGACG ACGGCAGCTT CTACGAACCC ACGGAGCTGA 300
CCAAGGACCA GCTGCGTCGT ATTCACACAA GGGAATACCT AAAGTCACTG CGCTGGAGCA 360
TGAATGTGGC CTGCATCGCT GAAGTGCCGC TGATGGCCTT CGTCCCGAAT CGATACATTC 420
AGCGTTCCTA TTTGCGACCC ATGCGCTTTC AAGCAGCCGG TTCCATTTTG GCCGGTAAGC 480
TGGCATTGGA TTATGGTTGG GCCATCAACC TGGGCGGTGG GTTCCATCAC TGTTGCTCGT 540
ACAGAGGCGG TGGTTTCTGT CCATATGCTG ACATCTCGCT GCTCATCGTC AGGCTGTTCG 600
AGCAGGAACC ATTCCGGGTG CGCCGCATAA TGATTGTGGA CCTGGATGCC CATCAGGGCA 660
ATGGGCACGA GCGGGACTTC AATAACGTGG CAGCCGTCTA CATTTTCGAC ATGTACAATG 720
CCTTTGTCTA TCCGCGGGAT CATGTGGCCA AGGAGAGCAT TCGGTGTGCG GTGGAGCTGC 780
GCAACTACAC GGAGGATGGA TTCTACCTGC GGCAACTAAA ACGCTGCCTG ATGCAGTCCC 840
TGGCCGAGTT CCGTCCAGAT ATGGTCGTCT ATAATGCGGG AACCGATGTG CTCGAGGGCG 900
ATCCATTGGG CAACCTGGCT ATTTCCGCGG AGGGCGTTAT TGAGCGGGAT CGGTTGGTAT 960
TTAGTACATT TCGGGCATTA GGAATTCCGG TGGTGATGCT GCTGAGTGGT GGCTACTTGA 1020
AGGCATCCGC AGGGGTAATT ACAGATTCGA TTGTTAATCT TCGGCTTCAA GGATTGCTAA 1080
ACTAAAGAAA TTAAAAATAT TTAAGACGAT AATATCGTCA AAACTTCGG
Nucleotide Fasta Sequence
>FBpp0084109|Class-I|Drosophila melanogaster
CCAATTCAACTGGTGTCGGACAGATGTAATCCACGCCTAAATTGAACCACAAAATGAAGCGCCTGACTGAGCGAGTGCACCACGAGGAGCAGGAGTCCGAGGAGGTTGTCTGGGTTAAGCGGGATGACGCACGCTCCGCCGGCAAACTGCCCATCGTGTTCTCAAGGAACTATGCGGTTCGCTTCGGTGGCCTTGAACGCCTACATCCCTTCGATGCGGCCAAGGGCAAGCACATTCACAAGCTCCTGTGCGCCCAACTGCAGCTCGACGACGGCAGCTTCTACGAACCCACGGAGCTGACCAAGGACCAGCTGCGTCGTATTCACACAAGGGAATACCTAAAGTCACTGCGCTGGAGCATGAATGTGGCCTGCATCGCTGAAGTGCCGCTGATGGCCTTCGTCCCGAATCGATACATTCAGCGTTCCTATTTGCGACCCATGCGCTTTCAAGCAGCCGGTTCCATTTTGGCCGGTAAGCTGGCATTGGATTATGGTTGGGCCATCAACCTGGGCGGTGGGTTCCATCACTGTTGCTCGTACAGAGGCGGTGGTTTCTGTCCATATGCTGACATCTCGCTGCTCATCGTCAGGCTGTTCGAGCAGGAACCATTCCGGGTGCGCCGCATAATGATTGTGGACCTGGATGCCCATCAGGGCAATGGGCACGAGCGGGACTTCAATAACGTGGCAGCCGTCTACATTTTCGACATGTACAATGCCTTTGTCTATCCGCGGGATCATGTGGCCAAGGAGAGCATTCGGTGTGCGGTGGAGCTGCGCAACTACACGGAGGATGGATTCTACCTGCGGCAACTAAAACGCTGCCTGATGCAGTCCCTGGCCGAGTTCCGTCCAGATATGGTCGTCTATAATGCGGGAACCGATGTGCTCGAGGGCGATCCATTGGGCAACCTGGCTATTTCCGCGGAGGGCGTTATTGAGCGGGATCGGTTGGTATTTAGTACATTTCGGGCATTAGGAATTCCGGTGGTGATGCTGCTGAGTGGTGGCTACTTGAAGGCATCCGCAGGGGTAATTACAGATTCGATTGTTAATCTTCGGCTTCAAGGATTGCTAAACTAAAGAAATTAAAAATATTTAAGACGATAATATCGTCAAAACTTCGG
|
| Sequence Source |
Ensembl |
| Keyword |
KW-0181--Complete proteome
KW-0378--Hydrolase
KW-1185--Reference proteome
--
|
| Interpro |
IPR000286--His_deacetylse
IPR023801--His_deacetylse_dom
|
| PROSITE |
|
| Pfam |
PF00850--Hist_deacetyl
|
| Gene Ontology |
GO:0004407--F:histone deacetylase activity
GO:0032041--F:NAD-dependent histone deacetylase activity (H3-K14 specific)
GO:0016575--P:histone deacetylation
|
| Orthology |
|
| Created Date |
25-Jun-2016 |
