WERAM Information

Tag Content
WERAM ID WERAM-Art-0035
Ensembl Protein ID AT2G02470.1
Uniprot Accession Q8S8M9; ALFL6_ARATH; F4IQE0; Q8LAH0
Genbank Protein ID NP_001189502.1; NP_178351.1
Protein Name PHD finger protein ALFIN-LIKE 6
Genbank Nucleotide ID NM_001202573.1; NM_126302.2
Gene Name ALFL6;AL6At2g02470;T16F16.26
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
AT2G02470 AT2G02470.1 AT2G02470.1
AT2G02470 AT2G02470.2 AT2G02470.2
Details
Type Family Domain Substrates AA References (PMIDs)
Me_Reader PHD PHD-type H3K4me3/2 K 19154204
Status Reviewed
Classification
Type Family E-value Score Start End
Me_Reader PHD 1.60e-12 48.2 202 251
Organism Arabidopsis thaliana
NCBI Taxa ID 3702
Functional Description
(View)		 Histone-binding component that specifically recognizes H3 tails trimethylated on 'Lys-4' (H3K4me3), which mark transcription start sites of virtually all active genes.
Domain Profile
  Me_Reader PHD
      PHD.txt   3 iClvCgkddegekemvqCdeCddwfHlkCvklplsslpegkswyCpsCke 52 
                  +C +Cg+++  ++++++Cd C++wfH+kCvk++  +++  k++ Cp+C +
  AT2G02470.1 202 VCGACGDNYGTDEFWICCDACEKWFHGKCVKITPAKAEHIKHYKCPTCSN 251
                  8****999999999*******************555554479******86 PP
Protein Sequence
(Fasta)		MEGITHPIPR TVEEVFSDFR GRRAGLIKAL TNDMVKFYQT CDPEKENLCL YGLPNETWEV 60
NLPVEEVPPE LPEPALGINF ARDGMQEKDW VSLVAVHSDS WLLSVAFYFG ARFGFGKNER 120
KRLFQMINEL PTIFEVVSGN AKQSKDLSVN NNNSKSKPSG VKSRQSESLS KVAKMSSPPP 180
KEEEEEEDES EDESEDDEQG AVCGACGDNY GTDEFWICCD ACEKWFHGKC VKITPAKAEH 240
IKHYKCPTCS NKRARP 256
Nucleotide Sequence
(Fasta)		GATCGGTCCC TTTTGTTTTA TCGTTTTAGG GTTTGTAGCT CCTTTCTCTT TTTTTCTTTT 60
CTCAATTTCC CCCAAATTAA AAAAAAACTC TCTCTTTCAG AGATTTACAA ATTTCATTTC 120
TCCAAATCCG AAACCCCAAA GTGAATATTT TTCCTTCTGG GTTTCTTTTG TTTGCCTGGA 180
AACATTTGTC TCAGATTTTG ATTTTGACCG GAGTACTCAT ATTCTCCGGC GATTTCTCCG 240
GCGACATCGT TTGTGAAATG GAGGGAATTA CTCATCCAAT ACCTCGTACT GTTGAAGAGG 300
TCTTTAGCGA CTTCAGAGGT CGACGAGCTG GTCTTATTAA AGCTCTCACT AATGATATGG 360
TGAAGTTTTA CCAAACGTGT GATCCTGAGA AGGAGAATTT GTGTCTCTAT GGACTTCCAA 420
ATGAGACATG GGAGGTTAAT CTACCCGTTG AGGAAGTTCC TCCTGAGCTT CCTGAACCAG 480
CTTTAGGCAT CAATTTCGCT AGAGACGGAA TGCAAGAAAA GGACTGGGTA TCTTTGGTCG 540
CAGTTCACAG TGATTCATGG CTGCTTTCTG TTGCATTTTA CTTTGGTGCA CGTTTCGGAT 600
TTGGCAAGAA TGAGAGGAAG AGGCTGTTCC AGATGATTAA TGAGCTGCCA ACCATTTTCG 660
AAGTTGTGAG CGGCAATGCA AAGCAGTCCA AGGATCTATC TGTTAACAAC AATAATAGCA 720
AAAGCAAACC TAGTGGCGTC AAGTCTCGCC AATCCGAATC TCTCTCAAAG GTTGCAAAGA 780
TGTCATCTCC ACCGCCAAAA GAAGAAGAAG AAGAAGAAGA TGAGAGTGAA GATGAGAGTG 840
AAGACGATGA ACAAGGTGCG GTTTGTGGTG CTTGTGGAGA CAACTACGGT ACAGATGAGT 900
TCTGGATTTG CTGCGACGCG TGTGAGAAAT GGTTCCATGG AAAATGTGTG AAGATAACAC 960
CTGCAAAAGC AGAACACATC AAGCATTACA AATGCCCAAC TTGCAGTAAC AAGAGAGCTA 1020
GACCTTGAAG TTAAATAACC AAATTATGAA AAGGTAAAGC GAGTTAGGAG AAAATTATGA 1080
AAGAAGAAGG TGAAGTTTCC AGTTTATAAG AAATGCCAGT AAAAGGGACT TAGAAGATGT 1140
AAGCAGGTAA AAAAAAAAAT TGTATTGCTT AGTCTTTATT GTTGGATTGA GACTATCTAC 1200
AGTTGGTGAT GTCTTTTCTT TTCTTTTTTT GGATTTTTGT TGTTGTTAAT GTTAATTCTA 1260
CTACTAATTT GTTTGGTCTG TTTAAGATAT TTTAGTTCTG ATTAGTAATT TTTTTTTTTT 1320
TT 1323
Sequence Source Ensembl
Keyword

KW-0025--Alternative splicing
KW-0156--Chromatin regulator
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0804--Transcription
KW-0805--Transcription regulation
KW-0862--Zinc
KW-0863--Zinc-finger
--
Interpro

IPR021998--Alfin
IPR019786--Zinc_finger_PHD-type_CS
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD
PROSITE

PS01359--ZF_PHD_1
PS50016--ZF_PHD_2
Pfam

PF12165--DUF3594
PF00628--PHD
Gene Ontology

GO:0005829--C:cytosol
GO:0005634--C:nucleus
GO:0008270--F:zinc ion binding
GO:0016036--P:cellular response to phosphate starvation
GO:0016568--P:chromatin modification
GO:0055065--P:metal ion homeostasis
GO:0006355--P:regulation of transcription, DNA-templated
GO:0048767--P:root hair elongation
GO:0006351--P:transcription, DNA-templated
Orthology
WERAM ID Ensembl Protein ID Species Identity E-value Score
WERAM-Arl-0130 scaffold_500181.1 Arabidopsis lyrata 94 5e-111 397
WERAM-Brr-0091 Bra017415.1-P Brassica rapa 87 4e-101 364
WERAM-Bro-0177 Bo9g072730.1 Brassica oleracea 87 2e-100 362
WERAM-Glm-0216 GLYMA17G00630.1 Glycine max 80 1e-97 352
WERAM-Pot-0035 POPTR_0003s04070.1 Populus trichocarpa 78 5e-96 347
WERAM-Prp-0081 EMJ24886 Prunus persica 82 7e-94 340
WERAM-Thc-0075 EOY26404 Theobroma cacao 79 1e-93 339
WERAM-Viv-0077 VIT_12s0035g01980.t01 Vitis vinifera 79 4e-93 337
WERAM-Met-0117 KEH32736 Medicago truncatula 77 7e-92 333
WERAM-Sol-0017 Solyc01g102750.2.1 Solanum lycopersicum 75 2e-88 322
WERAM-Sot-0055 PGSC0003DMT400047018 Solanum tuberosum 74 3e-87 318
WERAM-Mua-0010 GSMUA_Achr10P16300_001 Musa acuminata 71 2e-84 309
WERAM-Amt-0088 ERM99796 Amborella trichopoda 71 9e-84 306
WERAM-Orbr-0121 OB11G16440.1 Oryza brachyantha 73 2e-81 299
WERAM-Ors-0103 OS11T0244800-01 Oryza sativa 73 3e-81 298
WERAM-Orr-0116 ORUFI11G08380.1 Oryza rufipogon 73 3e-81 298
WERAM-Orni-0115 ONIVA11G08290.1 Oryza nivara 73 3e-81 298
WERAM-Orm-0100 OMERI11G06990.1 Oryza meridionalis 73 3e-81 298
WERAM-Ori-0116 BGIOSGA034217-PA Oryza indica 73 3e-81 298
WERAM-Orgl-0111 OGLUM11G07920.1 Oryza glumaepatula 73 3e-81 298
WERAM-Org-0108 ORGLA11G0071500.1 Oryza glaberrima 73 3e-81 298
WERAM-Orb-0115 OBART11G08090.1 Oryza barthii 73 3e-81 298
WERAM-Lep-0110 LPERR11G07220.1 Leersia perrieri 72 3e-81 298
WERAM-Sob-0124 Sb09g020610.1 Sorghum bicolor 69 4e-81 298
WERAM-Sei-0086 Si023009m Setaria italica 69 1e-80 296
WERAM-Orp-0107 OPUNC11G07880.1 Oryza punctata 73 3e-80 295
WERAM-Brd-0098 BRADI4G21040.1 Brachypodium distachyon 70 1e-79 293
WERAM-Zem-0090 GRMZM2G158918_P01 Zea mays 67 2e-79 292
WERAM-Aet-0106 EMT19247 Aegilops tauschii 67 3e-79 292
WERAM-Hov-0037 MLOC_37761.1 Hordeum vulgare 67 4e-79 291
WERAM-Tra-0353 TRAES3BF138600040CFD_t1 Triticum aestivum 66 4e-75 278
WERAM-Orl-0063 KN539254.1_FGP005 Oryza longistaminata 72 2e-73 273
WERAM-Php-0090 PP1S371_53V6.1 Physcomitrella patens 63 5e-72 268
WERAM-Sem-0147 EFJ25244 Selaginella moellendorffii 63 8e-69 257
Created Date 25-Jun-2016