Arabidopsis thaliana      HDAC      Class-I

※ Class-I family introduction

    Class-I: Class I HDACs share homology with the yeast Rpd3. This class includes HDACs 1, 2, 3, and 8, and its members are expressed ubiquitously in humans. Members 1, 2, and 3 are found in multi-protein repressor complexes in the nucleus, where they regulate gene expression. HDAC8 is found in both the nucleus and cytoplasm, and while it has not been found in any multi-protein complexes, it has been described to be involved in transcriptional repression. (1)

Reference
1. Koeneke, E., Witt, O., & Oehme, I.HDAC Family Members Intertwined in the Regulation of Autophagy: A Druggable Vulnerability in Aggressive Tumor Entities. Cells.2015;4(2):135-168. PMID: 25915736.



There are 12 genes.  Reviewed (12 or Unreviewed (0

No.StatusWERAM IDGene/Alias Name
1
WERAM-Art-0007
HDA8; At1g08460; T27G7.14; T27G7_7
2
WERAM-Art-0072
HDA15; At3g18520; MYF24_23
3
WERAM-Art-0080
HDA17; At3g44490; F14L2.40
4
WERAM-Art-0081
"HDA10,At3g44660; T18B22.60"
5
WERAM-Art-0082
HDA9; At3g44680; T18B22.80
6
WERAM-Art-0110
HDA14; At4g33470; F17M5.230
7
WERAM-Art-0112
HDA19; HD1; RPD3A; At4g38130; F20D10.250
8
WERAM-Art-0129
HDA2; At5g26040; T1N24.9
9
WERAM-Art-0132
HDA7; At5g35600; K2K18.5
10
WERAM-Art-0146
HDA5; At5g61060; MAF19.7
11
WERAM-Art-0147
HDA18; At5g61070; MAF19.8
12
WERAM-Art-0148
HDA6; RPD3B; At5g63110; MDC12.7