WERAM Information

Tag Content
WERAM ID WERAM-Hos-0094
Ensembl Protein ID ENSP00000312352.5
Uniprot Accession Q13029; PRDM2_HUMAN; B1AJZ4; B5MC68; Q13149; Q14550; Q5THJ1; Q5VUL9
Genbank Protein ID NP_001007258.1; NP_001129082.1; NP_036363.2; NP_056950.2; XP_005246055.1
Protein Name PR domain zinc finger protein 2
Genbank Nucleotide ID NM_001007257.2; NM_001135610.1; NM_012231.4; NM_015866.4; XM_005245998.2
Gene Name PRDM2;RIZ;KMT8;RIZ1;RIZ2;MTB-ZF;HUMHOXY1
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSG00000116731.22 ENST00000311066.9 ENSP00000312352.5
ENSG00000116731.22 ENST00000235372.11 ENSP00000235372.6
ENSG00000116731.22 ENST00000376048.9 ENSP00000365216.5
ENSG00000116731.22 ENST00000484063.6 ENSP00000423010.1
Details
Type Family Domain Substrates AA References (PMIDs)
HMT RIZ SET H3K9 K 25537518; 20951770; 20889125; 26807165
Status Reviewed
Classification
Type Family E-value Score Start End
HMT RIZ 5.90e-45 154.5 29 141
Organism Homo sapiens
NCBI Taxa ID 9606
Functional Description
(View)		 S-adenosyl-L-methionine-dependent histone methyltransferase that specifically methylates 'Lys-9' of histone H3. May function as a DNA-binding transcription factor. Binds to the macrophage-specific TPA-responsive element (MTE) of the HMOX1 (heme oxygenase 1) gene and may act as a transcriptional activator of this gene.
Domain Profile
  HMT RIZ
            RIZ.txt   2 evelaessipkeglgvyakkkiekgekfGPfvGekkileeveenanekliweisedkgevkyivDasdeeksnWlryvnvArskeeqNLaal 93 
                        ev+l++s+++k+++gv+a+k i kg+kfGPfvG+kk++++v++n    ++we++ + +  ++++Da+d+ek+nWlryvn+A+s eeqNL++l
  ENSP00000312352.5  29 EVRLFPSAVDKTRIGVWATKPILKGKKFGPFVGDKKKRSQVKNNV---YMWEVY-YPNLGWMCIDATDPEKGNWLRYVNWACSGEEQNLFPL 116
                        89*************************************999988...******.************************************* PP
            RIZ.txt  94 qineqifYktikdIepdeELLvwyk 118
                        +in++i+Ykt+k+I+p+eELLvwy+
  ENSP00000312352.5 117 EINRAIYYKTLKPIAPGEELLVWYN 141
                        ************************6 PP
Protein Sequence
(Fasta)		MNQNTTEPVA ATETLAEVPE HVLRGLPEEV RLFPSAVDKT RIGVWATKPI LKGKKFGPFV 60
GDKKKRSQVK NNVYMWEVYY PNLGWMCIDA TDPEKGNWLR YVNWACSGEE QNLFPLEINR 120
AIYYKTLKPI APGEELLVWY NGEDNPEIAA AIEEERASAR SKRSSPKSRK GKKKSQENKN 180
KGNKIQDIQL KTSEPDFTSA NMRDSAEGPK EDEEKPSASA LEQPATLQEV ASQEVPPELA 240
TPAPAWEPQP EPDERLEAAA CEVNDLGEEE EEEEEEDEEE EEDDDDDELE DEGEEEASMP 300
NENSVKEPEI RCDEKPEDLL EEPKTTSEET LEDCSEVTPA MQIPRTKEEA NGDVFETFMF 360
PCQHCERKFT TKQGLERHMH IHISTVNHAF KCKYCGKAFG TQINRRRHER RHEAGLKRKP 420
SQTLQPSEDL ADGKASGENV ASKDDSSPPS LGPDCLIMNS EKASQDTINS SVVEENGEVK 480
ELHPCKYCKK VFGTHTNMRR HQRRVHERHL IPKGVRRKGG LEEPQPPAEQ AQATQNVYVP 540
STEPEEEGEA DDVYIMDISS NISENLNYYI DGKIQTNNNT SNCDVIEMES ASADLYGINC 600
LLTPVTVEIT QNIKTTQVPV TEDLPKEPLG STNSEAKKRR TASPPALPKI KAETDSDPMV 660
PSCSLSLPLS ISTTEAVSFH KEKSVYLSSK LKQLLQTQDK LTPAGISATE IAKLGPVCVS 720
APASMLPVTS SRFKRRTSSP PSSPQHSPAL RDFGKPSDGK AAWTDAGLTS KKSKLESHSD 780
SPAWSLSGRD ERETVSPPCF DEYKMSKEWT ASSAFSSVCN QQPLDLSSGV KQKAEGTGKT 840
PVQWESVLDL SVHKKHCSDS EGKEFKESHS VQPTCSAVKK RKPTTCMLQK VLLNEYNGID 900
LPVENPADGT RSPSPCKSLE AQPDPDLGPG SGFPAPTVES TPDVCPSSPA LQTPSLSSGQ 960
LPPLLIPTDP SSPPPCPPVL TVATPPPPLL PTVPLPAPSS SASPHPCPSP LSNATAQSPL 1020
PILSPTVSPS PSPIPPVEPL MSAASPGPPT LSSSSSSSSS SSSFSSSSSS SSPSPPPLSA 1080
ISSVVSSGDN LEASLPMISF KQEELENEGL KPREEPQSAA EQDVVVQETF NKNFVCNVCE 1140
SPFLSIKDLT KHLSIHAEEW PFKCEFCVQL FKDKTDLSEH RFLLHGVGNI FVCSVCKKEF 1200
AFLCNLQQHQ RDLHPDKVCT HHEFESGTLR PQNFTDPSKA HVEHMQSLPE DPLETSKEEE 1260
ELNDSSEELY TTIKIMASGI KTKDPDVRLG LNQHYPSFKP PPFQYHHRNP MGIGVTATNF 1320
TTHNIPQTFT TAIRCTKCGK GVDNMPELHK HILACASASD KKRYTPKKNP VPLKQTVQPK 1380
NGVVVLDNSG KNAFRRMGQP KRLNFSVELS KMSSNKLKLN ALKKKNQLVQ KAILQKNKSA 1440
KQKADLKNAC ESSSHICPYC NREFTYIGSL NKHAAFSCPK KPLSPPKKKV SHSSKKGGHS 1500
SPASSDKNSN SNHRRRTADA EIKMQSMQTP LGKTRARSSG PTQVPLPSSS FRSKQNVKFA 1560
ASVKSKKPSS SSLRNSSPIR MAKITHVEGK KPKAVAKNHS AQLSSKTSRS LHVRVQKSKA 1620
VLQSKSTLAS KKRTDRFNIK SRERSGGPVT RSLQLAAAAD LSENKREDGS AKQELKDFRN 1680
FL 1682
Nucleotide Sequence
(Fasta)		GTAAAAGTGA CATTCTAAAT GTTCCTCACT CTGCGAGGCT TATTTTTTAG GGACTTTGCT 60
ATAATTCTGA AAGACTTAGT TTTACAGTAC ATCTGAAAGT AGGAGTTTTC AGAAGTATGG 120
CTCTTGGGAT AAATTTAGAT TCTTAATTGT GAAGCTCTGT TACCACTTGT TAGAAGGCAG 180
GTCAGCTCAC CTGCTTGGGG AGGTAAATAT ATGAATGCAC TCTCGAGTAA TTTAATGGAG 240
CCCTACCTCA ATGTACAGAA TGACAGTATC ACAGATCAAG AATGGAGTAC GAGTGATTTT 300
CGGCTATGGT GGGGGTAGGT AGGTCACTTG TCCCCTGTTG TCTCTTACTA TTTGTAAAGT 360
GAAGACTATG ATTAGTCTTT TTGATCGGGA TGGTTTGAGA TGAATAAAGA ATAGGCAGGC 420
AATTTGGATA CTTTAGGCTT TTCAAGAACA TTAGTAACAT TTTTTCTTAG ATATTTCTCC 480
TAATACAATG AGTGTTGTGA AATAACATGG CAGTTATTGT TGAGAGAAAA GCCTTCCCAG 540
TTATGTATTG AGTCCTTAGG CGTTTTGACC TTCCCTCCAC TCTTACAGAA CTTGGTGGAA 600
GGGGCCACTA TGTTTTCTAC CTCCTTCCGT GCCTTTCACA AAGCCACATC CTGCACCGTC 660
TACCCTTCTC TGTGGATATT TTTCCGCTTG GCAATTTCCT TTCCTGAGGC ACCCACTTGG 720
GACATCTGAA TCTCCATCTC CATGTTGATG GCCCGTTTGT GCTTGGACGT GTTCTTCCAC 780
TTGAGACTGA GGGTTCATGT AATCAAAGAA GTTTCTTTGT TGTGTGTATC TTTACAGAAC 840
ACAACAGGAA TTGAAAATGA ATCAGAACAC TACTGAGCCT GTGGCGGCCA CCGAGACCCT 900
GGCTGAGGTA CCCGAACATG TGCTGCGAGG ACTTCCGGAG GAAGTGAGGC TTTTCCCTTC 960
TGCTGTTGAC AAGACCCGGA TTGGTGTCTG GGCCACTAAA CCAATTTTAA AAGGCAAAAA 1020
ATTTGGGCCA TTTGTTGGTG ATAAGAAAAA AAGATCTCAG GTTAAGAATA ATGTATACAT 1080
GTGGGAGGTG TATTACCCAA ATTTGGGATG GATGTGCATT GATGCCACTG ATCCAGAGAA 1140
GGGAAACTGG CTGCGATATG TGAATTGGGC TTGCTCAGGA GAAGAGCAAA ATTTATTCCC 1200
ACTGGAAATC AACAGAGCCA TTTACTATAA AACTTTAAAG CCAATCGCGC CGGGCGAGGA 1260
GCTCCTGGTC TGGTACAATG GGGAAGACAA CCCTGAGATA GCAGCTGCGA TTGAGGAAGA 1320
GCGAGCCAGC GCCCGGAGCA AGCGGAGCTC CCCCAAGAGC CGGAAAGGGA AGAAAAAATC 1380
CCAGGAAAAT AAAAACAAAG GAAACAAAAT CCAAGACATA CAACTGAAGA CAAGTGAGCC 1440
AGATTTCACC TCTGCAAATA TGAGAGATTC TGCAGAAGGT CCTAAAGAAG ACGAAGAGAA 1500
GCCTTCAGCC TCAGCACTTG AGCAGCCGGC CACCCTCCAG GAGGTGGCCA GTCAGGAGGT 1560
GCCTCCAGAA CTAGCAACCC CTGCCCCTGC CTGGGAGCCA CAGCCAGAAC CAGACGAGCG 1620
ATTAGAAGCG GCAGCTTGTG AGGTGAATGA TTTGGGGGAA GAGGAGGAGG AGGAAGAGGA 1680
GGAGGATGAA GAAGAAGAAG AAGATGATGA TGATGATGAG TTGGAAGACG AGGGGGAAGA 1740
AGAAGCCAGC ATGCCAAATG AAAATTCTGT GAAAGAGCCA GAAATACGGT GTGATGAGAA 1800
GCCAGAAGAT TTATTAGAGG AACCAAAAAC AACTTCAGAA GAAACTCTTG AAGACTGCTC 1860
AGAGGTAACA CCTGCCATGC AAATCCCCAG AACTAAAGAA GAGGCCAATG GTGATGTATT 1920
TGAAACGTTT ATGTTTCCGT GTCAACATTG TGAAAGGAAG TTTACAACCA AACAGGGGCT 1980
TGAGCGTCAC ATGCATATCC ATATATCCAC CGTCAATCAT GCTTTCAAAT GCAAGTACTG 2040
TGGGAAAGCC TTTGGCACAC AGATTAACCG GCGGCGACAT GAGCGGCGCC ATGAAGCAGG 2100
GTTAAAGCGG AAACCCAGCC AAACACTACA GCCGTCAGAG GATCTGGCTG ATGGCAAAGC 2160
ATCTGGAGAA AACGTTGCTT CAAAAGATGA TTCGAGTCCT CCCAGTCTTG GGCCAGACTG 2220
TCTGATCATG AATTCAGAGA AGGCTTCCCA AGACACAATA AATTCTTCTG TCGTAGAAGA 2280
GAATGGGGAA GTTAAAGAAC TTCATCCGTG CAAATATTGT AAAAAGGTTT TTGGAACTCA 2340
TACTAATATG AGACGGCATC AGCGTAGAGT TCACGAACGT CATCTGATTC CCAAAGGTGT 2400
ACGGCGAAAA GGAGGCCTTG AAGAGCCCCA GCCTCCAGCA GAACAGGCCC AGGCCACCCA 2460
GAACGTGTAT GTACCAAGCA CAGAGCCGGA GGAGGAAGGG GAAGCAGATG ATGTGTACAT 2520
CATGGACATT TCTAGCAATA TCTCTGAAAA CTTAAATTAC TATATTGATG GTAAAATTCA 2580
AACTAATAAC AACACTAGTA ACTGTGATGT GATTGAGATG GAGTCTGCTT CGGCAGATTT 2640
GTATGGTATA AATTGTCTGC TCACTCCAGT TACAGTGGAA ATTACTCAAA ATATAAAGAC 2700
CACACAGGTC CCTGTAACAG AAGATCTTCC TAAAGAGCCT TTGGGCAGCA CAAATAGTGA 2760
GGCCAAGAAG CGGAGAACTG CGAGCCCACC TGCACTGCCC AAAATTAAGG CCGAAACAGA 2820
CTCTGACCCC ATGGTCCCCT CTTGCTCTTT AAGTCTTCCT CTTAGCATAT CAACAACAGA 2880
GGCAGTGTCT TTCCACAAAG AGAAAAGTGT TTATTTGTCA TCAAAGCTCA AACAACTTCT 2940
TCAAACCCAA GATAAACTAA CTCCTGCAGG GATTTCAGCA ACTGAAATAG CTAAATTAGG 3000
TCCTGTTTGT GTGTCTGCTC CTGCATCAAT GTTGCCTGTG ACCTCAAGTA GGTTTAAGAG 3060
GCGGACCAGC TCTCCTCCCA GTTCTCCACA GCACAGTCCT GCCCTTCGAG ACTTTGGAAA 3120
GCCAAGTGAT GGGAAAGCAG CATGGACCGA TGCCGGGCTG ACTTCCAAAA AATCCAAATT 3180
AGAAAGTCAC AGCGACTCAC CAGCATGGAG TTTGTCTGGG AGAGATGAGA GAGAAACTGT 3240
GAGCCCTCCA TGCTTTGATG AATATAAAAT GTCTAAAGAG TGGACAGCTA GTTCTGCTTT 3300
TAGCAGTGTG TGCAACCAGC AGCCACTGGA TTTATCCAGC GGTGTCAAAC AGAAGGCTGA 3360
GGGTACAGGC AAGACTCCAG TCCAGTGGGA ATCTGTCTTA GATCTCAGTG TGCATAAAAA 3420
GCATTGTAGT GACTCTGAAG GCAAGGAATT CAAAGAAAGT CATTCAGTGC AGCCTACGTG 3480
TAGTGCTGTA AAGAAAAGGA AACCAACCAC CTGCATGCTG CAGAAGGTTC TTCTCAATGA 3540
ATATAATGGC ATCGATTTAC CTGTAGAAAA CCCTGCAGAT GGGACCAGGA GCCCAAGTCC 3600
TTGTAAATCC CTAGAAGCTC AGCCAGATCC TGACCTCGGT CCGGGCTCTG GTTTCCCTGC 3660
CCCTACTGTT GAGTCCACAC CTGATGTTTG TCCTTCATCA CCTGCCCTGC AGACACCCTC 3720
CCTTTCATCC GGTCAGCTGC CTCCTCTCTT GATCCCCACA GATCCCTCTT CCCCTCCACC 3780
CTGTCCCCCG GTATTAACTG TTGCCACTCC GCCCCCTCCC CTCCTTCCTA CCGTACCTCT 3840
TCCAGCCCCC TCTTCCAGTG CATCTCCACA CCCATGCCCC TCTCCACTCT CAAATGCCAC 3900
CGCACAGTCC CCACTTCCAA TTCTGTCCCC AACAGTGTCC CCCTCTCCCT CTCCCATTCC 3960
TCCCGTGGAG CCCCTGATGT CTGCCGCCTC ACCCGGGCCT CCAACACTTT CTTCTTCCTC 4020
CTCTTCATCT TCCTCCTCCT CTTCGTTTTC TTCTTCATCT TCCTCCTCTT CTCCTTCTCC 4080
ACCTCCTCTC TCCGCAATAT CATCTGTTGT TTCCTCTGGT GATAATCTGG AGGCTTCTCT 4140
CCCCATGATA TCTTTCAAAC AGGAGGAATT AGAGAATGAA GGTCTGAAAC CCAGGGAAGA 4200
GCCCCAGTCT GCTGCTGAAC AGGATGTTGT TGTTCAGGAA ACATTCAACA AAAACTTTGT 4260
TTGCAACGTC TGTGAATCAC CTTTTCTTTC CATTAAAGAT CTAACCAAAC ATTTATCTAT 4320
TCATGCTGAA GAATGGCCCT TCAAATGTGA ATTTTGTGTG CAGCTTTTTA AGGATAAAAC 4380
GGACTTGTCA GAACATCGCT TTTTGCTTCA TGGAGTTGGG AATATCTTTG TGTGTTCTGT 4440
TTGTAAAAAA GAATTTGCTT TTTTGTGCAA TTTGCAGCAG CACCAGCGAG ATCTCCACCC 4500
AGATAAGGTG TGCACACATC ACGAGTTTGA AAGCGGGACT CTGAGGCCCC AGAACTTTAC 4560
AGATCCCAGC AAGGCCCATG TAGAGCATAT GCAGAGCTTG CCAGAAGATC CTTTAGAAAC 4620
TTCTAAAGAA GAAGAGGAGT TAAATGATTC CTCTGAAGAG CTTTACACGA CTATAAAAAT 4680
AATGGCTTCT GGAATAAAGA CAAAAGATCC AGATGTTCGA TTGGGCCTCA ATCAGCATTA 4740
CCCAAGCTTT AAACCACCTC CATTTCAGTA CCATCACCGT AACCCCATGG GGATTGGTGT 4800
GACAGCCACA AATTTCACTA CACACAATAT TCCACAGACT TTCACTACCG CCATTCGCTG 4860
CACAAAGTGT GGAAAAGGTG TCGACAATAT GCCGGAGTTG CACAAACATA TCCTGGCTTG 4920
TGCTTCTGCA AGTGACAAGA AGAGGTACAC GCCTAAGAAA AACCCAGTAC CATTAAAACA 4980
AACTGTGCAA CCCAAAAATG GCGTGGTGGT TTTAGATAAC TCTGGGAAAA ATGCCTTCCG 5040
ACGAATGGGA CAGCCCAAAA GGCTTAACTT TAGTGTTGAG CTCAGCAAAA TGTCGTCGAA 5100
TAAGCTCAAA TTAAATGCAT TGAAGAAAAA AAATCAGCTA GTACAGAAAG CAATTCTTCA 5160
GAAAAACAAA TCTGCAAAGC AGAAGGCCGA CTTGAAAAAT GCTTGTGAGT CATCCTCTCA 5220
CATCTGCCCT TACTGTAATC GAGAGTTCAC TTACATTGGA AGCCTGAATA AACACGCCGC 5280
CTTCAGCTGT CCCAAAAAAC CCCTTTCTCC TCCCAAAAAA AAAGTTTCTC ATTCATCTAA 5340
GAAAGGTGGA CACTCATCAC CTGCAAGTAG TGACAAAAAC AGTAACAGCA ACCACCGCAG 5400
ACGGACAGCG GATGCGGAGA TTAAAATGCA AAGCATGCAG ACTCCGTTGG GCAAGACCAG 5460
AGCCCGCAGC TCAGGCCCCA CCCAAGTCCC ACTTCCCTCC TCATCCTTCA GGTCCAAGCA 5520
GAACGTCAAG TTTGCAGCTT CGGTGAAATC CAAAAAACCA AGCTCCTCCT CTTTAAGGAA 5580
CTCCAGCCCG ATAAGAATGG CCAAAATAAC TCATGTTGAG GGGAAAAAAC CTAAAGCTGT 5640
GGCCAAGAAT CATTCTGCTC AGCTTTCCAG CAAAACATCA CGGAGCCTGC ACGTGAGGGT 5700
ACAGAAAAGC AAAGCTGTTT TACAAAGCAA ATCCACCTTG GCGAGTAAGA AAAGAACAGA 5760
CCGGTTCAAT ATAAAATCTA GAGAGCGGAG TGGGGGGCCA GTCACCCGGA GCCTTCAGCT 5820
GGCAGCTGCT GCTGACTTGA GTGAGAACAA GAGAGAGGAC GGCAGCGCCA AGCAGGAGCT 5880
GAAGGACTTC AGGAACTTCC TGTAGAAAAG CCCCCAAAAC AAAACAAACC TTAATTGACT 5940
AAAAAGTATT GCATGCTCAA CTTAGGATAA GCACTACGGC AAAGGATACG AAATCTACCA 6000
AGCTTGCAAG ACCAGTTGAA GCTGACTCAA AAATCCTAAC ATTCAGCTGA TTGCCGGCAG 6060
GCTTAGAGTC AGGCATCTGC TGCTTCGGTG GGGGCCCAAC GCGCATGCTG GGCGCCCGGG 6120
TGATTGAGAT CCAAAGAGAA GGGCACTGTA AGACAGGCCA GATGAACTGG CTCCTCGTCA 6180
TGGGACTGGT ACCTCAGATC TGAGCATGGC CCTTGTTTTT GGCACGTAGC AGAGAAAGGA 6240
TTGATTTGAA CTTAACCTTG CAAAGCAAGT TGCCTGTTTT AGCAGTAGTT TGTTGTAGGT 6300
TTCAGGGATG ACAGATTTGG ATGCACTCAT TTAAAACGTT TTGGTCACAT ATCAGCTCTT 6360
GATGCCTTTC TTTTAAATTA ATTATAGACA GAGAGAGGCA TTTAGCTGAT CTCTTACCCC 6420
TGGTATTTCT TTTTTTTGTT GTTTTCGTTT TTTTAAATCA CAAGTAGATT GCCAGCGTAA 6480
TGGAGAGGAA ACCAGATTGG ATATGGACTC TTTTTTATGC CTATTCTGGT GTTGCGTTTG 6540
TATATCCAAA TGGACGTTAT CCTCTCAGAT TCTTATCTGG CACTAATTTA TAACTATTAT 6600
ATTATCAGAG ACTATGTAGC AATATATCAG TGCACAGGCG CATCCCAGGC CTGTACAGAT 6660
GTATGTCTAC ACGTAAGTAT AAATGAATTT GCATACCAGG TTTTACACTT GCATCTCTAA 6720
TAGAGATTAA AAACAACAAA TTGGCCTCTT CCTAAGTATA TTAATATCAT TTATCCTTAC 6780
ATTTTATGCC TCCCCCTAAA TTAATGACTG AGTTGGTGGA AAGCGGCTAG GTTTTATTCA 6840
TACTGTTTTT TGTTCTCAAC TTCAAAAGTA ATCTACCTCT GAAAAATTTG TAGTTTAATA 6900
TTTGTTTGGT GAATTTGTGC CACTTTAATC CTTCCACTAT CATTCCCATT TTGTTACATT 6960
TCTGTTATGG GGACTTTATG TTGAAATATT GTATAAAGCA TTTGTAGCAA TTTAAAAATA 7020
AAATATTTAA AATTATTTAA ATTGTTTTGG ACGCTTCAAT TGTATTATAT GTGATTTACA 7080
TTTCACTTTT TTTGTTGGCG TTGTTAACCC GGAGAGTGCT CCTGTATTGA ACTTTGCTGT 7140
TAGTTATTTT ATTGCTTCTT TTTGGAGAGT GCTATAAAAG ACTATTCTAA TGAAAACATT 7200
AAAATTTACA ATTTGACATA CAAAAAGGGG TTGTCCATTG ATTTTAACCA ATGTAGCACT 7260
GAGAGAGAGA GAGGTTAATT ATAGATAGAC AAGAGTGGTG TTTGTTGTTT TTCCCCTCCC 7320
AGCATTGAAA TCATTGGGGC TTGTCAGATG TATTAAAAAA AGATTTGTTG TGCTATTGCT 7380
GCAAACACTT AATAACTAGA GGAGAATTTA AACAATGCAT TTTATATTAT TGTAACC 7438
Sequence Source Ensembl
Keyword

KW-0002--3D-structure
KW-0010--Activator
KW-0024--Alternative initiation
KW-0025--Alternative splicing
KW-0181--Complete proteome
KW-0238--DNA-binding
KW-1017--Isopeptide bond
KW-0479--Metal-binding
KW-0489--Methyltransferase
KW-0539--Nucleus
KW-0597--Phosphoprotein
KW-0621--Polymorphism
KW-1185--Reference proteome
KW-0677--Repeat
KW-0949--S-adenosyl-L-methionine
KW-0804--Transcription
KW-0805--Transcription regulation
KW-0808--Transferase
KW-0832--Ubl conjugation
KW-0862--Zinc
KW-0863--Zinc-finger
--
Interpro

IPR009170--RIZ_retinblastoma-bd_prot
IPR001214--SET_dom
IPR007087--Znf_C2H2
IPR015880--Znf_C2H2-like
IPR013087--Znf_C2H2/integrase_DNA-bd
PROSITE

PS50280--SET
PS00028--ZINC_FINGER_C2H2_1
PS50157--ZINC_FINGER_C2H2_2
Pfam

PF00856--SET
PF13912--zf-C2H2_6
Gene Ontology

GO:0005634--C:nucleus
GO:0003677--F:DNA binding
GO:0018024--F:histone-lysine N-methyltransferase activity
GO:0003700--F:transcription factor activity, sequence-specific DNA binding
GO:0008270--F:zinc ion binding
GO:0008340--P:determination of adult lifespan
GO:0006355--P:regulation of transcription, DNA-templated
GO:0032355--P:response to estradiol
GO:0006351--P:transcription, DNA-templated
Orthology
WERAM ID Ensembl Protein ID Species Identity E-value Score
WERAM-Poa-0014 ENSPPYP00000002150.2 Pongo abelii 98 0.0 1602
WERAM-Chs-0010 ENSCSAP00000017181.1 Chlorocebus sabaeus 97 0.0 1587
WERAM-Gog-0062 ENSGGOP00000005565.2 Gorilla gorilla 94 0.0 1560
WERAM-Dan-0095 ENSDNOP00000010065.3 Dasypus novemcinctus 84 0.0 1370
WERAM-Mim-0159 ENSMICP00000016213.1 Microcebus murinus 87 0.0 1369
WERAM-Loa-0113 ENSLAFP00000010222.3 Loxodonta africana 85 0.0 1353
WERAM-Eqc-0052 ENSECAP00000006928.1 Equus caballus 83 0.0 1350
WERAM-Cap-0158 ENSCPOP00000013075.2 Cavia porcellus 83 0.0 1346
WERAM-Myl-0079 ENSMLUP00000006376.2 Myotis lucifugus 84 0.0 1338
WERAM-Ptv-0104 ENSPVAP00000009366.1 Pteropus vampyrus 82 0.0 1337
WERAM-Prc-0128 ENSPCAP00000011552.1 Procavia capensis 81 0.0 1320
WERAM-Dio-0121 ENSDORP00000011807.1 Dipodomys ordii 81 0.0 1305
WERAM-Tut-0059 ENSTTRP00000004738.1 Tursiops truncatus 82 0.0 1294
WERAM-Ran-0182 ENSRNOP00000046011.3 Rattus norvegicus 80 0.0 1283
WERAM-Bot-0175 ENSBTAP00000027387.5 Bos taurus 82 0.0 1280
WERAM-Mum-0203 ENSMUSP00000101404.1 Mus musculus 81 0.0 1266
WERAM-Ova-0117 ENSOARP00000011454.1 Ovis aries 76 0.0 1223
WERAM-Ocp-0072 ENSOPRP00000006314.1 Ochotona princeps 73 0.0 1165
WERAM-Mod-0102 ENSMODP00000035055.3 Monodelphis domestica 72 0.0 1033
WERAM-Sah-0163 ENSSHAP00000017120.1 Sarcophilus harrisii 68 0.0 1028
WERAM-Soa-0065 ENSSARP00000006475.1 Sorex araneus 93 0.0 980
WERAM-Anp-0137 ENSAPLP00000014610.1 Anas platyrhynchos 61 0.0 959
WERAM-Gaga-0044 ENSGALP00000006497.4 Gallus gallus 66 0.0 958
WERAM-Meg-0061 ENSMGAP00000005838.2 Meleagris gallopavo 62 0.0 909
WERAM-Fia-0122 ENSFALP00000010367.1 Ficedula albicollis 63 0.0 886
WERAM-Ect-0043 ENSETEP00000004327.1 Echinops telfairi 83 0.0 885
WERAM-Mae-0058 ENSMEUP00000005635.1 Macropus eugenii 80 0.0 849
WERAM-Xet-0166 ENSXETP00000029499.3 Xenopus tropicalis 65 0.0 636
WERAM-Lac-0030 ENSLACP00000005070.2 Latimeria chalumnae 66 9e-180 629
WERAM-Dar-0174 ENSDARP00000098393.2 Danio rerio 41 1e-136 485
WERAM-Orn-0043 ENSONIP00000004947.1 Oreochromis niloticus 50 6e-129 460
WERAM-Orla-0041 ENSORLP00000004978.1 Oryzias latipes 49 3e-127 454
WERAM-Tar-0175 ENSTRUP00000037071.1 Takifugu rubripes 51 4e-125 447
WERAM-Gaa-0013 ENSGACP00000001573.1 Gasterosteus aculeatus 49 7e-125 446
WERAM-Ten-0181 ENSTNIP00000017818.1 Tetraodon nigroviridis 47 3e-124 444
WERAM-Pof-0174 ENSPFOP00000024474.1 Poecilia formosa 46 2e-117 422
WERAM-Xim-0213 ENSXMAP00000017089.1 Xiphophorus maculatus 54 1e-116 419
WERAM-Mam-0159 ENSMMUP00000025737.2 Macaca mulatta 99 6e-85 314
WERAM-Fec-0210 ENSFCAP00000022446.1 Felis catus 98 7e-84 310
WERAM-Caj-0142 ENSCJAP00000025355.2 Callithrix jacchus 92 1e-75 283
WERAM-Mup-0197 ENSMPUP00000016975.1 Mustela putorius furo 39 8e-21 101
WERAM-Paa-0092 ENSPANP00000006501.1 Papio anubis 39 3e-18 92.8
WERAM-Anc-0054 ENSACAP00000005392.3 Anolis carolinensis 42 3e-18 92.8
WERAM-Sus-0183 ENSSSCP00000023246.1 Sus scrofa 37 2e-17 90.1
WERAM-Caf-0202 ENSCAFP00000028796.4 Canis familiaris 36 4e-17 89.0
WERAM-Orc-0206 ENSOCUP00000023211.2 Oryctolagus cuniculus 36 4e-17 89.0
WERAM-Pes-0005 ENSPSIP00000002371.1 Pelodiscus sinensis 37 1e-16 87.4
WERAM-Leo-0040 ENSLOCP00000005995.1 Lepisosteus oculatus 34 2e-16 87.0
WERAM-Chh-0087 ENSCHOP00000009921.1 Choloepus hoffmanni 41 2e-16 86.7
WERAM-Asm-0040 ENSAMXP00000005078.1 Astyanax mexicanus 41 3e-16 85.9
WERAM-Ora-0042 ENSOANP00000006627.1 Ornithorhynchus anatinus 38 4e-16 85.5
WERAM-Aim-0022 ENSAMEP00000001535.1 Ailuropoda melanoleuca 38 6e-16 85.1
WERAM-Vip-0114 ENSVPAP00000010581.1 Vicugna pacos 42 7e-16 84.7
WERAM-Otg-0147 ENSOGAP00000012568.2 Otolemur garnettii 39 8e-16 84.7
WERAM-Pem-0083 ENSPMAP00000008984.1 Petromyzon marinus 34 1e-15 84.3
WERAM-Ict-0141 ENSSTOP00000014774.2 Ictidomys tridecemlineatus 41 1e-15 84.0
WERAM-Tub-0028 ENSTBEP00000003557.1 Tupaia belangeri 39 1e-15 84.0
WERAM-Pat-0154 ENSPTRP00000031523.3 Pan troglodytes 42 3e-15 82.8
WERAM-Nol-0147 ENSNLEP00000016062.1 Nomascus leucogenys 42 3e-15 82.8
WERAM-Tas-0102 ENSTSYP00000010720.1 Tarsius syrichta 41 4e-15 82.4
WERAM-Tag-0018 ENSTGUP00000001146.1 Taeniopygia guttata 37 8e-15 81.3
WERAM-Gam-0040 ENSGMOP00000004090.1 Gadus morhua 30 5e-14 78.6
WERAM-Ere-0093 ENSEEUP00000009413.1 Erinaceus europaeus 35 1e-12 74.3
Created Date 25-Jun-2016