Tag |
Content |
WERAM ID |
WERAM-Mum-0004 |
Ensembl Protein ID |
ENSMUSP00000000724.8 |
Uniprot Accession |
Q9JHD1; KAT2B_MOUSE; Q3U142; Q640M9 |
Genbank Protein ID |
NP_064389.2 |
Protein Name |
Histone acetyltransferase KAT2B |
Genbank Nucleotide ID |
NM_020005.4 |
Gene Name |
KAT2B;PCAF;Pcaf |
Ensembl Information |
|
Details |
Type |
Family |
Domain |
Substrates |
AA |
References (PMIDs) |
Ac_Reader |
Bromodomain |
Bromodomain |
|
K |
14731392 |
HAT |
GCN5 |
N-acetyltransferase |
H3K9; H3K14 |
K |
26193056; 23927873 |
|
Status |
Reviewed |
Classification |
Type |
Family |
E-value |
Score |
Start |
End |
HAT |
GCN5 |
5.70e-69 |
232.7 |
484 |
755 |
Ac_Reader |
Bromodomain |
5.80e-23 |
82.2 |
721 |
791 |
|
Organism |
Mus musculus |
NCBI Taxa ID |
10090 |
Functional Description (View)Functional Description
Functions as a histone acetyltransferase (HAT) to promote transcriptional activation. Has significant histone acetyltransferase activity with core histones (H3 and H4), and also with nucleosome core particles. Also acetylates non-histone proteins, such as ACLY. Acts as a circadian transcriptional coactivator which enhances the activity of the circadian transcriptional activators: NPAS2-ARNTL/BMAL1 and CLOCK-ARNTL/BMAL1 heterodimers (By similarity). |
Functions as a histone acetyltransferase (HAT) to promote transcriptional activation. Has significant histone acetyltransferase activity with core histones (H3 and H4), and also with nucleosome core particles. Also acetylates non-histone proteins, such as ACLY. Acts as a circadian transcriptional coactivator which enhances the activity of the circadian transcriptional activators: NPAS2-ARNTL/BMAL1 and CLOCK-ARNTL/BMAL1 heterodimers (By similarity).
|
Domain Profile |
HAT GCN5
GCN5.txt 2 leksrvdevllvlvglqkvfeaqlprmkkeyiarlladrkhkslvvikkdngvvggitfrlfeeegfvEvvycavaskervkGyGkrLl 90 l+++ ++++l++lvglq+vf++qlprm+keyi+rl++d+khk+l++ik d +v+ggi+fr+f+++gf+E+v+cav+s+e+vkGyG++L+ ENSMUSP00000000724.8 484 LNQKPNKKILMWLVGLQNVFSHQLPRMPKEYITRLVFDPKHKTLALIK-DGRVIGGICFRMFPSQGFTEIVFCAVTSNEQVKGYGTHLM 571 8999********************************************.**************************************** PP GCN5.txt 91 nhlkevarktrrikffLTfadneaigyfkkqgfskeiklpksstigyikeyegatllecele 152 nhlke+++k ++i +fLT+ad++aigyfkkqgfskeik+pk++++gyik+yegatl+ cel+ ENSMUSP00000000724.8 572 NHLKEYHIK-HEILNFLTYADEYAIGYFKKQGFSKEIKIPKTKYVGYIKDYEGATLMGCELN 632 *********.*************************************************985 PP GCN5.txt 89 LlnhlkevarktrrikffLTfadneaigyfkkqgfskeiklpk 131 L n+l++v ++ + f+ + ea gy++ f+ ++k + ENSMUSP00000000724.8 713 LKNILQQVKNHPNAWPFMEPVKRTEAPGYYEVIRFPMDLKTMS 755 6689999999988888888899999*****9999988887655 PP
Ac_Reader Bromodomain
BROMO.txt 1 kehevsepFrepvdpqleipdYydiikePmdLstikerleegnYsspeefvkDvrlifnNakaynenkssvq 72 k+h+ ++pF+epv++ e+p Yy++i+ PmdL+t+ erl++++Y s + f++D++++f+N+k+yn+++s+++ ENSMUSP00000000724.8 721 KNHPNAWPFMEPVKR-TEAPGYYEVIRFPMDLKTMSERLRNRYYVSKKLFMADLQRVFTNCKEYNPPESEYY 791 5799***********.7****************************************************997 PP
|
Protein Sequence (Fasta) | MAEAGGAGSP ALPPAPPHGS PRTLATAAGS SASCGPATAV AAAGTAEGPG GGGSARIAVK 60 KAQLRSAPRA KKLEKLGVYS ACKAEESCKC NGWKNPNPSP TPPRGDLQQI IVSLTESCRS 120 CSHALAAHVS HLENVSEEEM DRLLGIVLDV EYLFTCVHKE EDADTKQVYF YLFKLLRKSI 180 LQRGKPVVEG SLEKKPPFEK PSIEQGVNNF VQYKFSHLPS KERQTTIELA KMFLNRINYW 240 HLEAPSQRRL RSPNDDISGY KENYTRWLCY CNVPQFCDSL PRYETTKVFG RTLLRSVFTI 300 MRRQLLEQAR QEKDKLPLEK RTLILTHFPK FLSMLEEEVY SQNSPIWDQD FLSASSRTSP 360 LGIQTVISPP VTGTALFSSN STSHEQINGG RTSPGCRGSS GLEANPGEKR KMNNSHAPEE 420 AKRSRVMGDI PVELINEVMS TITDPAGMLG PETNFLSAHS ARDEAARLEE RRGVIEFHVV 480 GNSLNQKPNK KILMWLVGLQ NVFSHQLPRM PKEYITRLVF DPKHKTLALI KDGRVIGGIC 540 FRMFPSQGFT EIVFCAVTSN EQVKGYGTHL MNHLKEYHIK HEILNFLTYA DEYAIGYFKK 600 QGFSKEIKIP KTKYVGYIKD YEGATLMGCE LNPQIPYTEF SVIIKKQKEI IKKLIERKQA 660 QIRKVYPGLS CFKDGVRQIP IESIPGIRET GWKPSGKEKS KEPKDPEQLY STLKNILQQV 720 KNHPNAWPFM EPVKRTEAPG YYEVIRFPMD LKTMSERLRN RYYVSKKLFM ADLQRVFTNC 780 KEYNPPESEY YKCASILEKF FFSKIKEAGL IDK 813Protein Fasta Sequence
>ENSMUSP00000000724.8|KAT2B;PCAF;Pcaf|Mus musculus MAEAGGAGSPALPPAPPHGSPRTLATAAGSSASCGPATAVAAAGTAEGPGGGGSARIAVKKAQLRSAPRAKKLEKLGVYSACKAEESCKCNGWKNPNPSPTPPRGDLQQIIVSLTESCRSCSHALAAHVSHLENVSEEEMDRLLGIVLDVEYLFTCVHKEEDADTKQVYFYLFKLLRKSILQRGKPVVEGSLEKKPPFEKPSIEQGVNNFVQYKFSHLPSKERQTTIELAKMFLNRINYWHLEAPSQRRLRSPNDDISGYKENYTRWLCYCNVPQFCDSLPRYETTKVFGRTLLRSVFTIMRRQLLEQARQEKDKLPLEKRTLILTHFPKFLSMLEEEVYSQNSPIWDQDFLSASSRTSPLGIQTVISPPVTGTALFSSNSTSHEQINGGRTSPGCRGSSGLEANPGEKRKMNNSHAPEEAKRSRVMGDIPVELINEVMSTITDPAGMLGPETNFLSAHSARDEAARLEERRGVIEFHVVGNSLNQKPNKKILMWLVGLQNVFSHQLPRMPKEYITRLVFDPKHKTLALIKDGRVIGGICFRMFPSQGFTEIVFCAVTSNEQVKGYGTHLMNHLKEYHIKHEILNFLTYADEYAIGYFKKQGFSKEIKIPKTKYVGYIKDYEGATLMGCELNPQIPYTEFSVIIKKQKEIIKKLIERKQAQIRKVYPGLSCFKDGVRQIPIESIPGIRETGWKPSGKEKSKEPKDPEQLYSTLKNILQQVKNHPNAWPFMEPVKRTEAPGYYEVIRFPMDLKTMSERLRNRYYVSKKLFMADLQRVFTNCKEYNPPESEYYKCASILEKFFFSKIKEAGLIDK
|
Nucleotide Sequence (Fasta) | GGGTCTCGGC GCGGGAGGGT GTCAGGCCCA GGGACGCCAG CAGCGCAGGG CGGCAGGTGC 60 CTGGGCTGCA GCGGCCCGGT CTCGCGGGTC GCCGGTCACC TACGGGCCCT GGCGCTCCCG 120 GCGGGCGGCT ACGCTCGCAG CAGCATGCCG GAGGCCCAGG GGAGCAGAGC GCGGCCAAGG 180 CGCTCGGGCC CGCTAGCGTC CTAGCCGCCT GGGGAGGCGC GGGGGCCTGC GATCGCTGGC 240 GGCCGAGTGC GGCGGGGGCG GGGAGGGCGC AGGGCGGCGG CCGGGGGGGG GGGAGGGTCT 300 CGGCTCCGCC ACCAGCGCCC GCGGGGACCC TGGCAGCTGC GGGTGACAGT CGGGGCGGCA 360 TGGCCGAGGC TGGCGGGGCC GGGTCCCCAG CACTGCCTCC CGCGCCCCCG CACGGTTCCC 420 CCCGGACCCT GGCCACCGCT GCCGGGAGCT CTGCTTCCTG CGGGCCAGCG ACCGCGGTGG 480 CCGCGGCGGG CACGGCCGAG GGACCGGGAG GAGGCGGCTC GGCCCGGATC GCCGTGAAGA 540 AGGCGCAGTT GCGCTCTGCT CCGCGGGCGA AGAAGCTGGA GAAACTCGGC GTGTACTCCG 600 CCTGCAAGGC AGAGGAGTCC TGTAAATGCA ATGGCTGGAA GAACCCTAAC CCCTCTCCTA 660 CTCCACCAAG AGGAGACCTC CAGCAGATAA TTGTCAGTTT GACAGAATCC TGTCGAAGCT 720 GTAGCCATGC CCTTGCTGCT CACGTTTCTC ACTTGGAGAA TGTGTCAGAG GAAGAGATGG 780 ACAGACTCCT GGGAATTGTG TTGGATGTGG AGTACCTCTT CACCTGCGTC CACAAAGAAG 840 AAGATGCAGA TACCAAACAA GTGTACTTCT ACCTATTCAA GCTCTTGAGA AAGTCAATTT 900 TACAAAGAGG AAAACCTGTG GTTGAAGGCT CCTTGGAGAA GAAGCCGCCA TTTGAGAAGC 960 CCAGTATTGA ACAGGGTGTG AACAACTTCG TGCAGTACAA GTTTAGTCAC TTGCCATCGA 1020 AAGAGAGGCA GACAACGATC GAGCTGGCCA AGATGTTTCT GAACCGCATC AACTACTGGC 1080 ATCTGGAGGC TCCATCTCAG CGGAGACTAC GGTCTCCCAA TGATGACATC TCTGGATACA 1140 AGGAAAACTA CACAAGGTGG TTGTGCTACT GCAATGTACC GCAGTTCTGT GACAGCTTAC 1200 CTCGGTACGA AACCACAAAG GTGTTTGGGA GAACATTGCT TCGCTCGGTC TTCACCATCA 1260 TGAGACGACA GCTCTTGGAA CAAGCCAGAC AGGAAAAAGA CAAACTGCCT CTTGAGAAAC 1320 GCACGCTTAT CCTCACACAT TTCCCAAAGT TTCTGTCCAT GTTGGAAGAA GAAGTGTATA 1380 GTCAAAATTC TCCTATCTGG GATCAGGATT TTCTCTCAGC CTCTTCCAGA ACCAGCCCGC 1440 TAGGAATCCA AACAGTAATC AGTCCTCCTG TTACTGGGAC AGCATTGTTC AGTTCAAATT 1500 CCACTTCCCA TGAGCAGATC AATGGAGGGA GAACAAGTCC TGGATGCAGA GGCTCTTCTG 1560 GGCTTGAAGC AAACCCGGGA GAAAAGAGGA AAATGAACAA CTCTCATGCT CCCGAGGAGG 1620 CCAAGAGATC TCGAGTGATG GGGGATATTC CCGTGGAATT GATCAATGAG GTCATGTCTA 1680 CCATCACAGA CCCTGCAGGG ATGCTTGGAC CAGAGACCAA TTTTCTGTCA GCCCATTCGG 1740 CCAGAGATGA GGCGGCACGG CTGGAAGAAC GCAGGGGTGT CATTGAATTC CACGTGGTGG 1800 GCAACTCCCT GAACCAGAAA CCAAACAAGA AGATCCTGAT GTGGCTCGTG GGCCTCCAGA 1860 ATGTGTTTTC CCACCAGCTG CCCAGAATGC CCAAAGAGTA CATCACACGG CTCGTCTTTG 1920 ACCCGAAACA CAAAACCCTT GCTTTAATTA AAGATGGCCG TGTCATTGGT GGTATCTGTT 1980 TCCGGATGTT TCCATCCCAG GGATTCACAG AGATTGTTTT CTGTGCAGTA ACCTCAAATG 2040 AACAAGTCAA GGGCTATGGA ACCCACCTGA TGAACCATCT CAAAGAATAC CACATAAAGC 2100 ACGAGATCCT CAACTTCCTC ACATATGCAG ATGAGTATGC CATCGGCTAT TTCAAGAAGC 2160 AGGGTTTCTC CAAAGAAATC AAAATACCTA AAACCAAATA TGTTGGCTAC ATCAAGGATT 2220 ATGAAGGGGC CACTTTGATG GGATGTGAGC TGAACCCTCA GATCCCATAC ACAGAGTTCT 2280 CTGTCATCAT TAAAAAGCAG AAGGAGATCA TTAAAAAGCT GATAGAAAGA AAACAAGCCC 2340 AGATTCGAAA AGTCTACCCT GGACTTTCGT GTTTCAAAGA TGGAGTTCGG CAGATTCCTA 2400 TAGAAAGCAT TCCTGGAATC AGAGAGACAG GCTGGAAACC AAGTGGAAAA GAGAAAAGTA 2460 AAGAGCCCAA AGACCCTGAG CAGCTTTACA GCACCCTCAA GAACATCCTG CAGCAGGTGA 2520 AGAACCATCC AAATGCTTGG CCTTTCATGG AACCAGTGAA GAGAACAGAA GCTCCGGGAT 2580 ATTATGAAGT TATAAGGTTC CCCATGGATC TGAAAACCAT GAGTGAACGC CTCAGGAACA 2640 GGTACTATGT GTCTAAGAAG TTATTCATGG CGGACTTGCA ACGAGTGTTC ACCAACTGCA 2700 AGGAGTACAA CCCTCCCGAG AGCGAGTACT ACAAATGCGC CAGCATCCTG GAGAAGTTCT 2760 TCTTCAGTAA AATTAAGGAA GCAGGGTTGA TTGACAAGTG ATTTCTTTCC CTTAGACACA 2820 CATCAGCAGT GTGCCTAAAA CAGGTCATTT AGGTTTTTGG TTGCTTTTGT TTTTTTGTTT 2880 TTGTTTTTAA ATTGTACATC ATGTGTTGAA GAGACTTGTA ATAATTAGCA CTTTTGAAAA 2940 ACAAACAAAA CCTCCTTTTA GCTTTTCAGA GACGTATTTA AATGGAAATC ATAGATTTTT 3000 TTTTTATTTT GAGCAATAGA TTTTAATCTA TTTACTACTA TCATGTAATT TTTCTCTGGC 3060 ATGTCCAGTA GCTGACTATT GCATGGTAGA TGATCAGGGG CTTCCTCAAA ACCTGTATGT 3120 GAGGAAATTG CACACAGTAC CAAGATTTGG GGTAATCTAG AGAAAAGTTT GACCATGAAT 3180 GTCTCCATTT TTTTTCTAAT GGAACATGAG AGTTTATTTT ATTCTGAAGG ACTTTAAAGG 3240 GTCCGTGACA CACCTGTGCT GTGAATGAAC TGTGTGATGT TTGAAGTCTC CTTGTAGACT 3300 TTTTATAAGT ATATATTTTT AAAACACTCA TCTAGATGAG GTGCTTTGAG CAGTTCTGAA 3360 AAAAAAAAAT GCAGCTTCCA CAATAGCGGC TGCTATGACT CCTAAGGAAG GGACTTTTTA 3420 TAAGCTCCTG GGGCTTTGAT CATTCTGTCT ACCTATTACA GACTTGAGAG TGCACAACCA 3480 CTATTTAATA ATATCTTGGC AGATATGTGT CCATCTCATA TTTGACTTTG CTTGTGCAGG 3540 GCCCAACTTC TAAAAGATCC GTTCCCAGGC CACAAAGGTG TTAGCTTGAA AATATTTGAG 3600 GTTGAGTTAA TGTTAAGACA TGTGGCCTAA ACATGAACCC AGGGGAGCCT TGCTTCACTA 3660 TGTAAGGATT CTTTGTATTT TCTGGTACAT TTAACCCCAT CACCAGTGTC TATGTGAACA 3720 TTTCCCATTT GCACTTCCAG AGTTTTGTTT GTCTGAGGTG AACTGAATTC TCACCAAAGT 3780 TTAGGCCAGT ATTTTAACAC CTCCATTGTT TTATTGGTCC AGGGTTATAT CCCACTAACA 3840 TTCGCTGTAC AATCTTATTA ACCATTTTTG TCTTGGGACT CCAGCTTAGT GCTTGGATTT 3900 ATTTCCTAAT TACACTACAT AGAAAAGTGG GACACCTGCC AGCCCAACTC TGGGAAAAAC 3960 CAACTAATAT ACAACCATAT TAAATGAAGG CCACCTTAAT GGTCTCGACA CTAATTTTTA 4020 TGATGCAAAT TTATAAACTG ATTTTTTTGT AAAGGCTGAG GTTTTAAAAA TGTATTTAAT 4080 GTATGTTTTC TATCCGCATA AATTATATTG GGTCACTAAT AGTCATTAAA AATAGCTTGC 4140 AGAGGTAGTG TGCTTGAAGG AAAATATCCT GGCATTGCTC CCGAGTGCTG CTTCTGACAT 4200 GGAAGGCATG CTGTATGTTC ATAGTGTTCA CTGAAGATCA CACTGAAGAT GCCTCAACAT 4260 TGGGAAATGT AAGGAACACT TTGAGTGGTA TCTAGACTAT TAATGAAGAG TGATAATAGA 4320 GGCTGCATTA AGTGTCTCAG ACTGGTTTTA AAACAGCTTT GTACCGATTT CGCTGAAGCG 4380 TCTGTCCAGT TTGGTATCCT GTGAAAGTTT GTTATTTCCT GGGTAGACAT CCTTAAAGAG 4440 TATTGTCTTT AAAATCAGAT GGTCTCTTCT ATATTGAAAG CATTTTTATG TTTTCTAATT 4500 TAAAATTAAT ATTTTCTTAT AGATATTGTG CAATAAAGCA GAAGTAGAAT GTGGTTTTTG 4560 CAAATGCTTT AACGGCCGAC AAAAACTTTA CATTTGTAAA ATTAATATAT TGTACTGGTA 4620 CAAAATAGTT TTAAATTATA TTTTGAAAAG CTC
4654Nucleotide Fasta Sequence
>ENSMUSP00000000724.8|Bromodomain|Mus musculus GGGTCTCGGCGCGGGAGGGTGTCAGGCCCAGGGACGCCAGCAGCGCAGGGCGGCAGGTGCCTGGGCTGCAGCGGCCCGGTCTCGCGGGTCGCCGGTCACCTACGGGCCCTGGCGCTCCCGGCGGGCGGCTACGCTCGCAGCAGCATGCCGGAGGCCCAGGGGAGCAGAGCGCGGCCAAGGCGCTCGGGCCCGCTAGCGTCCTAGCCGCCTGGGGAGGCGCGGGGGCCTGCGATCGCTGGCGGCCGAGTGCGGCGGGGGCGGGGAGGGCGCAGGGCGGCGGCCGGGGGGGGGGGAGGGTCTCGGCTCCGCCACCAGCGCCCGCGGGGACCCTGGCAGCTGCGGGTGACAGTCGGGGCGGCATGGCCGAGGCTGGCGGGGCCGGGTCCCCAGCACTGCCTCCCGCGCCCCCGCACGGTTCCCCCCGGACCCTGGCCACCGCTGCCGGGAGCTCTGCTTCCTGCGGGCCAGCGACCGCGGTGGCCGCGGCGGGCACGGCCGAGGGACCGGGAGGAGGCGGCTCGGCCCGGATCGCCGTGAAGAAGGCGCAGTTGCGCTCTGCTCCGCGGGCGAAGAAGCTGGAGAAACTCGGCGTGTACTCCGCCTGCAAGGCAGAGGAGTCCTGTAAATGCAATGGCTGGAAGAACCCTAACCCCTCTCCTACTCCACCAAGAGGAGACCTCCAGCAGATAATTGTCAGTTTGACAGAATCCTGTCGAAGCTGTAGCCATGCCCTTGCTGCTCACGTTTCTCACTTGGAGAATGTGTCAGAGGAAGAGATGGACAGACTCCTGGGAATTGTGTTGGATGTGGAGTACCTCTTCACCTGCGTCCACAAAGAAGAAGATGCAGATACCAAACAAGTGTACTTCTACCTATTCAAGCTCTTGAGAAAGTCAATTTTACAAAGAGGAAAACCTGTGGTTGAAGGCTCCTTGGAGAAGAAGCCGCCATTTGAGAAGCCCAGTATTGAACAGGGTGTGAACAACTTCGTGCAGTACAAGTTTAGTCACTTGCCATCGAAAGAGAGGCAGACAACGATCGAGCTGGCCAAGATGTTTCTGAACCGCATCAACTACTGGCATCTGGAGGCTCCATCTCAGCGGAGACTACGGTCTCCCAATGATGACATCTCTGGATACAAGGAAAACTACACAAGGTGGTTGTGCTACTGCAATGTACCGCAGTTCTGTGACAGCTTACCTCGGTACGAAACCACAAAGGTGTTTGGGAGAACATTGCTTCGCTCGGTCTTCACCATCATGAGACGACAGCTCTTGGAACAAGCCAGACAGGAAAAAGACAAACTGCCTCTTGAGAAACGCACGCTTATCCTCACACATTTCCCAAAGTTTCTGTCCATGTTGGAAGAAGAAGTGTATAGTCAAAATTCTCCTATCTGGGATCAGGATTTTCTCTCAGCCTCTTCCAGAACCAGCCCGCTAGGAATCCAAACAGTAATCAGTCCTCCTGTTACTGGGACAGCATTGTTCAGTTCAAATTCCACTTCCCATGAGCAGATCAATGGAGGGAGAACAAGTCCTGGATGCAGAGGCTCTTCTGGGCTTGAAGCAAACCCGGGAGAAAAGAGGAAAATGAACAACTCTCATGCTCCCGAGGAGGCCAAGAGATCTCGAGTGATGGGGGATATTCCCGTGGAATTGATCAATGAGGTCATGTCTACCATCACAGACCCTGCAGGGATGCTTGGACCAGAGACCAATTTTCTGTCAGCCCATTCGGCCAGAGATGAGGCGGCACGGCTGGAAGAACGCAGGGGTGTCATTGAATTCCACGTGGTGGGCAACTCCCTGAACCAGAAACCAAACAAGAAGATCCTGATGTGGCTCGTGGGCCTCCAGAATGTGTTTTCCCACCAGCTGCCCAGAATGCCCAAAGAGTACATCACACGGCTCGTCTTTGACCCGAAACACAAAACCCTTGCTTTAATTAAAGATGGCCGTGTCATTGGTGGTATCTGTTTCCGGATGTTTCCATCCCAGGGATTCACAGAGATTGTTTTCTGTGCAGTAACCTCAAATGAACAAGTCAAGGGCTATGGAACCCACCTGATGAACCATCTCAAAGAATACCACATAAAGCACGAGATCCTCAACTTCCTCACATATGCAGATGAGTATGCCATCGGCTATTTCAAGAAGCAGGGTTTCTCCAAAGAAATCAAAATACCTAAAACCAAATATGTTGGCTACATCAAGGATTATGAAGGGGCCACTTTGATGGGATGTGAGCTGAACCCTCAGATCCCATACACAGAGTTCTCTGTCATCATTAAAAAGCAGAAGGAGATCATTAAAAAGCTGATAGAAAGAAAACAAGCCCAGATTCGAAAAGTCTACCCTGGACTTTCGTGTTTCAAAGATGGAGTTCGGCAGATTCCTATAGAAAGCATTCCTGGAATCAGAGAGACAGGCTGGAAACCAAGTGGAAAAGAGAAAAGTAAAGAGCCCAAAGACCCTGAGCAGCTTTACAGCACCCTCAAGAACATCCTGCAGCAGGTGAAGAACCATCCAAATGCTTGGCCTTTCATGGAACCAGTGAAGAGAACAGAAGCTCCGGGATATTATGAAGTTATAAGGTTCCCCATGGATCTGAAAACCATGAGTGAACGCCTCAGGAACAGGTACTATGTGTCTAAGAAGTTATTCATGGCGGACTTGCAACGAGTGTTCACCAACTGCAAGGAGTACAACCCTCCCGAGAGCGAGTACTACAAATGCGCCAGCATCCTGGAGAAGTTCTTCTTCAGTAAAATTAAGGAAGCAGGGTTGATTGACAAGTGATTTCTTTCCCTTAGACACACATCAGCAGTGTGCCTAAAACAGGTCATTTAGGTTTTTGGTTGCTTTTGTTTTTTTGTTTTTGTTTTTAAATTGTACATCATGTGTTGAAGAGACTTGTAATAATTAGCACTTTTGAAAAACAAACAAAACCTCCTTTTAGCTTTTCAGAGACGTATTTAAATGGAAATCATAGATTTTTTTTTTATTTTGAGCAATAGATTTTAATCTATTTACTACTATCATGTAATTTTTCTCTGGCATGTCCAGTAGCTGACTATTGCATGGTAGATGATCAGGGGCTTCCTCAAAACCTGTATGTGAGGAAATTGCACACAGTACCAAGATTTGGGGTAATCTAGAGAAAAGTTTGACCATGAATGTCTCCATTTTTTTTCTAATGGAACATGAGAGTTTATTTTATTCTGAAGGACTTTAAAGGGTCCGTGACACACCTGTGCTGTGAATGAACTGTGTGATGTTTGAAGTCTCCTTGTAGACTTTTTATAAGTATATATTTTTAAAACACTCATCTAGATGAGGTGCTTTGAGCAGTTCTGAAAAAAAAAAATGCAGCTTCCACAATAGCGGCTGCTATGACTCCTAAGGAAGGGACTTTTTATAAGCTCCTGGGGCTTTGATCATTCTGTCTACCTATTACAGACTTGAGAGTGCACAACCACTATTTAATAATATCTTGGCAGATATGTGTCCATCTCATATTTGACTTTGCTTGTGCAGGGCCCAACTTCTAAAAGATCCGTTCCCAGGCCACAAAGGTGTTAGCTTGAAAATATTTGAGGTTGAGTTAATGTTAAGACATGTGGCCTAAACATGAACCCAGGGGAGCCTTGCTTCACTATGTAAGGATTCTTTGTATTTTCTGGTACATTTAACCCCATCACCAGTGTCTATGTGAACATTTCCCATTTGCACTTCCAGAGTTTTGTTTGTCTGAGGTGAACTGAATTCTCACCAAAGTTTAGGCCAGTATTTTAACACCTCCATTGTTTTATTGGTCCAGGGTTATATCCCACTAACATTCGCTGTACAATCTTATTAACCATTTTTGTCTTGGGACTCCAGCTTAGTGCTTGGATTTATTTCCTAATTACACTACATAGAAAAGTGGGACACCTGCCAGCCCAACTCTGGGAAAAACCAACTAATATACAACCATATTAAATGAAGGCCACCTTAATGGTCTCGACACTAATTTTTATGATGCAAATTTATAAACTGATTTTTTTGTAAAGGCTGAGGTTTTAAAAATGTATTTAATGTATGTTTTCTATCCGCATAAATTATATTGGGTCACTAATAGTCATTAAAAATAGCTTGCAGAGGTAGTGTGCTTGAAGGAAAATATCCTGGCATTGCTCCCGAGTGCTGCTTCTGACATGGAAGGCATGCTGTATGTTCATAGTGTTCACTGAAGATCACACTGAAGATGCCTCAACATTGGGAAATGTAAGGAACACTTTGAGTGGTATCTAGACTATTAATGAAGAGTGATAATAGAGGCTGCATTAAGTGTCTCAGACTGGTTTTAAAACAGCTTTGTACCGATTTCGCTGAAGCGTCTGTCCAGTTTGGTATCCTGTGAAAGTTTGTTATTTCCTGGGTAGACATCCTTAAAGAGTATTGTCTTTAAAATCAGATGGTCTCTTCTATATTGAAAGCATTTTTATGTTTTCTAATTTAAAATTAATATTTTCTTATAGATATTGTGCAATAAAGCAGAAGTAGAATGTGGTTTTTGCAAATGCTTTAACGGCCGACAAAAACTTTACATTTGTAAAATTAATATATTGTACTGGTACAAAATAGTTTTAAATTATATTTTGAAAAGCTC
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Sequence Source |
Ensembl |
Keyword |
KW-0010--Activator KW-0012--Acyltransferase KW-0090--Biological rhythms KW-0103--Bromodomain KW-0131--Cell cycle KW-0181--Complete proteome KW-0539--Nucleus KW-1185--Reference proteome KW-0804--Transcription KW-0805--Transcription regulation KW-0808--Transferase --
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Interpro |
IPR016181--Acyl_CoA_acyltransferase IPR001487--Bromodomain IPR018359--Bromodomain_CS IPR000182--GNAT_dom IPR016376--Hist_acetylase_PCAF IPR009464--PCAF_N
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PROSITE |
PS00633--BROMODOMAIN_1 PS50014--BROMODOMAIN_2 PS51186--GNAT
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Pfam |
PF00583--Acetyltransf_1 PF00439--Bromodomain PF06466--PCAF_N
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Gene Ontology |
GO:0031672--C:A band GO:0042641--C:actomyosin GO:0005671--C:Ada2/Gcn5/Ada3 transcription activator complex GO:0005829--C:cytosol GO:0000123--C:histone acetyltransferase complex GO:0031674--C:I band GO:0000776--C:kinetochore GO:0000790--C:nuclear chromatin GO:0005654--C:nucleoplasm GO:0005634--C:nucleus GO:0016407--F:acetyltransferase activity GO:0003682--F:chromatin binding GO:0004861--F:cyclin-dependent protein serine/threonine kinase inhibitor activity GO:0004402--F:histone acetyltransferase activity GO:0042826--F:histone deacetylase binding GO:0004468--F:lysine N-acetyltransferase activity, acting on acetyl phosphate as donor GO:0032403--F:protein complex binding GO:0019901--F:protein kinase binding GO:0000977--F:RNA polymerase II regulatory region sequence-specific DNA binding GO:0003713--F:transcription coactivator activity GO:0003712--F:transcription cofactor activity GO:0008134--F:transcription factor binding GO:0007049--P:cell cycle GO:0032869--P:cellular response to insulin stimulus GO:0034599--P:cellular response to oxidative stress GO:0071374--P:cellular response to parathyroid hormone stimulus GO:0006338--P:chromatin remodeling GO:0016573--P:histone acetylation GO:0043966--P:histone H3 acetylation GO:0043970--P:histone H3-K9 acetylation GO:0018393--P:internal peptidyl-lysine acetylation GO:0007613--P:memory GO:0018076--P:N-terminal peptidyl-lysine acetylation GO:0008285--P:negative regulation of cell proliferation GO:0045736--P:negative regulation of cyclin-dependent protein serine/threonine kinase activity GO:0007219--P:Notch signaling pathway GO:0018394--P:peptidyl-lysine acetylation GO:0035563--P:positive regulation of chromatin binding GO:0035948--P:positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter GO:0071442--P:positive regulation of histone H3-K14 acetylation GO:2000617--P:positive regulation of histone H3-K9 acetylation GO:0010976--P:positive regulation of neuron projection development GO:0045944--P:positive regulation of transcription from RNA polymerase II promoter GO:0045893--P:positive regulation of transcription, DNA-templated GO:0045909--P:positive regulation of vasodilation GO:0006473--P:protein acetylation GO:0010835--P:regulation of protein ADP-ribosylation GO:0006355--P:regulation of transcription, DNA-templated GO:0048511--P:rhythmic process GO:0006361--P:transcription initiation from RNA polymerase I promoter
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Orthology |
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Created Date |
25-Jun-2016 |