| Tag |
Content |
| WERAM ID |
WERAM-Drm-0019 |
| Ensembl Protein ID |
FBpp0075701 |
| Uniprot Accession |
Q9VTZ1; Q9VTZ1_DROME
|
| Genbank Protein ID |
NP_648586.2
|
| Protein Name |
GH11602p |
| Genbank Nucleotide ID |
NM_140329.3
|
| Gene Name |
GCN5;Pcaf;CG4107 |
| Ensembl Information |
|
| Details |
| Type |
Family |
Domain |
Substrates |
AA |
References (PMIDs) |
| Ac_Reader |
Bromodomain |
Bromodomain |
H3K9; H3K14 |
K |
25251222; 16135811
|
| HAT |
GCN5 |
N-acetyltransferase |
H3K9; H3K14; H3K18; H3K36 |
K |
25959239; 16135811; 18022374
|
|
| Status |
Reviewed |
| Classification |
| Type |
Family |
E-value |
Score |
Start |
End |
| HAT |
GCN5 |
4.70e-62 |
209.3 |
479 |
627 |
| Ac_Reader |
Bromodomain |
2.40e-24 |
85.8 |
722 |
791 |
|
| Organism |
Drosophila melanogaster |
| NCBI Taxa ID |
7227 |
Functional Description
(View) |
|
| Domain Profile |
HAT GCN5
GCN5.txt 2 leksrvdevllvlvglqkvfeaqlprmkkeyiarlladrkhkslvvikkdngvvggitfrlfeeegfvEvvycavaskervkGyGkrLlnhlkevark 99
l+k +++++l+l glq vf+ qlp+m++eyi++l++d+khk+l++ik +n+++ggi+fr+f+++gf+E+v+cav+++e+vkGyG++L+nhlk+++++
FBpp0075701 479 LTKPVDKQTVLWLLGLQLVFAYQLPEMPREYISQLVFDTKHKTLALIK-ENQPIGGICFRPFPSQGFTEIVFCAVTMSEQVKGYGTHLMNHLKDYSIQ 575
6788899999**************************************.************************************************* PP
GCN5.txt 100 trrikffLTfadneaigyfkkqgfskeiklpksstigyikeyegatllecele 152
r ik++LTfad++aigyfkkqgfsk+ikl +++++gyikey++atl++cel+
FBpp0075701 576 -RGIKHLLTFADCDAIGYFKKQGFSKDIKLARPVYAGYIKEYDSATLMHCELH 627
.*************************************************986 PP
Ac_Reader Bromodomain
BROMO.txt 2 ehevsepFrepvdpqleipdYydiikePmdLstikerleegnYsspeefvkDvrlifnNakaynenkssvq 72
+h ++pF +pv + +e+pdYyd ik PmdL+t+ erl++g+Y++ f++D+ +if+N++ yn+++++++
FBpp0075701 722 QHTTAWPFLRPVTA-AEVPDYYDHIKYPMDLKTMGERLKKGYYQTRRLFMADMARIFSNCRFYNSPDTEYY 791
7999**********.8****************************************************997 PP
|
Protein Sequence
(Fasta) | MSGGPSITIK SQPIDGNNTG NAAAQQQQQA ANGAATAGAS GAAGSAQNPG HGGAASGAGS 60
VPAEGTRQNS LQRIQQRKQK VFNLPVPQKL AKLSMYSACQ SEGCRCTGWK TPQENRHRDV 120
ESSYCPEFNE ECRNTSCRHS LRSHIAHLDN ISSSSMNELL GAIIDMENLF MSMQRVEDED 180
TKKVYQYLFR LLRQCVLTRQ QAVIRGPLGD PPFETPCITK AVLSLVFYKY NHLSTPELQT 240
MTEVAKTFLN FLNHYNFESP STRRGDLTHE DASNYKINYT RWLVFCHVPA FCNSLRQCET 300
SLVFGRTLLR TVFQCMSQQL KKKCISERDR FPEDKRSIIT LMPKFLETLR AELLKDDSPI 360
WDTSYRPSNS FVIQQRKRNQ EVANVPIGPS AASIGGNKRT SVGEPLHKRI KKEPTDRPSS 420
ENLDDLPADV VMRAMKSVSE SKTTNKAEIL FPVNVSRDEN VKAEEQKRAI EFHVVGNSLT 480
KPVDKQTVLW LLGLQLVFAY QLPEMPREYI SQLVFDTKHK TLALIKENQP IGGICFRPFP 540
SQGFTEIVFC AVTMSEQVKG YGTHLMNHLK DYSIQRGIKH LLTFADCDAI GYFKKQGFSK 600
DIKLARPVYA GYIKEYDSAT LMHCELHPSI VNTQFIAVIR SQSEILKELI AQRHNEVQKV 660
RPGLTCFKEG LPVIPVESIP GLREIGWKPQ NRPARSSRPL EESTDPEKLA TSFASVLQSV 720
RQHTTAWPFL RPVTAAEVPD YYDHIKYPMD LKTMGERLKK GYYQTRRLFM ADMARIFSNC 780
RFYNSPDTEY YRCANSLERY FQTKMRELGL WDK 813Protein Fasta Sequence
>FBpp0075701|GCN5;Pcaf;CG4107|Drosophila melanogaster
MSGGPSITIKSQPIDGNNTGNAAAQQQQQAANGAATAGASGAAGSAQNPGHGGAASGAGSVPAEGTRQNSLQRIQQRKQKVFNLPVPQKLAKLSMYSACQSEGCRCTGWKTPQENRHRDVESSYCPEFNEECRNTSCRHSLRSHIAHLDNISSSSMNELLGAIIDMENLFMSMQRVEDEDTKKVYQYLFRLLRQCVLTRQQAVIRGPLGDPPFETPCITKAVLSLVFYKYNHLSTPELQTMTEVAKTFLNFLNHYNFESPSTRRGDLTHEDASNYKINYTRWLVFCHVPAFCNSLRQCETSLVFGRTLLRTVFQCMSQQLKKKCISERDRFPEDKRSIITLMPKFLETLRAELLKDDSPIWDTSYRPSNSFVIQQRKRNQEVANVPIGPSAASIGGNKRTSVGEPLHKRIKKEPTDRPSSENLDDLPADVVMRAMKSVSESKTTNKAEILFPVNVSRDENVKAEEQKRAIEFHVVGNSLTKPVDKQTVLWLLGLQLVFAYQLPEMPREYISQLVFDTKHKTLALIKENQPIGGICFRPFPSQGFTEIVFCAVTMSEQVKGYGTHLMNHLKDYSIQRGIKHLLTFADCDAIGYFKKQGFSKDIKLARPVYAGYIKEYDSATLMHCELHPSIVNTQFIAVIRSQSEILKELIAQRHNEVQKVRPGLTCFKEGLPVIPVESIPGLREIGWKPQNRPARSSRPLEESTDPEKLATSFASVLQSVRQHTTAWPFLRPVTAAEVPDYYDHIKYPMDLKTMGERLKKGYYQTRRLFMADMARIFSNCRFYNSPDTEYYRCANSLERYFQTKMRELGLWDK |
Nucleotide Sequence
(Fasta) | ATCATTGCGC ACAGCAAGTG GGCAAACTCG TTGTATCGCT TGTGAAATTT AAGGAAAAGT 60
ACACTTTGTT CAAAACTAAC GAAGAGAATC GCAATATCTG CCGATCTTGG AATGTCTGGT 120
GGTCCATCCA TAACGATAAA AAGCCAACCA ATCGATGGTA ACAACACGGG CAACGCTGCG 180
GCGCAACAGC AGCAGCAGGC AGCGAATGGC GCAGCAACCG CTGGTGCATC TGGAGCCGCT 240
GGCAGCGCCC AGAATCCAGG ACACGGAGGA GCTGCGTCCG GCGCTGGCAG TGTGCCGGCA 300
GAGGGAACGC GCCAGAACAG CCTACAGCGC ATTCAGCAGC GAAAGCAAAA GGTCTTCAAT 360
CTGCCCGTGC CACAGAAACT GGCCAAATTG TCGATGTATT CCGCCTGCCA GTCTGAGGGA 420
TGCCGTTGCA CCGGCTGGAA GACACCGCAG GAAAATCGCC ACCGTGACGT CGAGTCCTCC 480
TACTGTCCGG AGTTCAACGA GGAGTGCCGC AACACCAGCT GTCGCCATTC GCTGAGATCG 540
CACATAGCCC ATCTGGACAA TATATCCAGT TCCAGCATGA ACGAGCTACT GGGCGCCATT 600
ATAGACATGG AGAACCTATT CATGTCCATG CAGCGCGTCG AGGACGAGGA CACCAAGAAG 660
GTGTACCAGT ACCTCTTCCG TTTGCTGCGC CAGTGCGTCC TCACGCGCCA GCAGGCGGTC 720
ATCCGGGGTC CTCTCGGCGA TCCACCATTC GAGACGCCGT GCATCACCAA GGCTGTGCTC 780
TCGTTGGTCT TCTACAAGTA CAATCACCTG AGCACGCCTG AACTCCAAAC CATGACCGAG 840
GTGGCCAAGA CGTTCTTGAA CTTTCTGAAC CACTACAACT TTGAATCGCC GTCGACCAGG 900
AGAGGAGATC TCACCCACGA GGATGCCTCT AACTACAAAA TCAACTACAC CAGGTGGTTG 960
GTGTTCTGCC ACGTGCCCGC CTTCTGTAAC TCCCTGCGCC AATGTGAAAC GTCCCTAGTG 1020
TTTGGACGAA CGCTCCTGCG CACCGTTTTC CAGTGCATGT CGCAGCAGCT GAAAAAGAAG 1080
TGCATCTCCG AGCGGGATCG CTTTCCCGAG GACAAGCGTT CGATCATCAC GCTGATGCCG 1140
AAGTTTTTGG AAACGCTTCG CGCCGAATTG CTCAAGGATG ATTCGCCCAT CTGGGATACC 1200
AGCTACCGCC CGTCAAATTC CTTTGTCATC CAGCAGAGAA AGCGTAACCA GGAGGTGGCA 1260
AATGTACCCA TTGGTCCCAG TGCAGCAAGC ATTGGTGGAA ACAAGAGGAC CAGTGTGGGT 1320
GAACCGCTCC ACAAGCGAAT CAAAAAGGAG CCCACCGATC GTCCAAGCAG TGAGAATTTG 1380
GATGACCTGC CTGCGGATGT AGTAATGCGC GCCATGAAAT CGGTGTCCGA GTCGAAGACC 1440
ACCAACAAAG CGGAAATTCT CTTTCCGGTT AATGTGTCGC GGGATGAGAA CGTCAAGGCG 1500
GAGGAGCAGA AGCGAGCCAT TGAGTTCCAT GTGGTGGGCA ATTCGCTGAC CAAACCGGTG 1560
GACAAGCAGA CTGTTTTGTG GCTACTGGGC CTGCAGCTCG TATTTGCCTA TCAGCTACCC 1620
GAGATGCCGC GCGAGTACAT CAGCCAGTTG GTTTTCGACA CCAAGCACAA AACACTGGCG 1680
CTCATCAAGG AAAACCAACC CATCGGCGGC ATCTGTTTCC GCCCGTTTCC GTCGCAAGGC 1740
TTCACCGAGA TCGTTTTCTG CGCGGTCACC ATGTCGGAAC AAGTTAAGGG CTATGGCACG 1800
CACTTGATGA ACCACTTGAA GGACTACAGC ATACAGAGGG GTATCAAGCA TCTGCTCACA 1860
TTCGCCGATT GCGATGCCAT CGGGTACTTC AAGAAGCAGG GTTTCTCCAA GGACATCAAA 1920
TTGGCGCGAC CAGTTTATGC GGGCTACATC AAGGAGTACG ATAGTGCTAC TCTCATGCAC 1980
TGCGAGCTGC ATCCAAGCAT TGTGAACACG CAGTTCATAG CTGTAATTCG CAGTCAGAGC 2040
GAGATTCTGA AGGAGCTGAT CGCACAGCGC CACAACGAGG TGCAGAAAGT AAGACCCGGC 2100
TTGACTTGCT TCAAGGAGGG CCTGCCCGTG ATTCCCGTGG AATCGATTCC TGGTCTGCGG 2160
GAGATCGGTT GGAAGCCGCA AAATCGTCCG GCGCGCTCAT CGCGACCCCT CGAGGAATCC 2220
ACCGATCCGG AGAAGCTGGC CACGTCCTTT GCATCCGTGC TGCAATCCGT GCGCCAGCAC 2280
ACCACCGCCT GGCCCTTCCT GCGCCCGGTG ACCGCGGCCG AAGTTCCGGA CTACTACGAT 2340
CACATTAAAT ATCCCATGGA CCTGAAGACC ATGGGCGAGC GCCTGAAGAA GGGTTACTAC 2400
CAAACGCGCC GCCTGTTCAT GGCGGACATG GCGCGCATTT TCTCCAACTG TCGGTTCTAC 2460
AATTCGCCCG ACACCGAGTA TTATCGGTGT GCCAACTCCC TGGAGCGCTA CTTCCAGACC 2520
AAGATGCGCG AGCTGGGGCT GTGGGACAAA TGATGCAGTG ATTCCGAGGA GCCCTGCATA 2580
AGGCCGAACA TTTAATCGAA CTAAATTATT ATATTAATTC TATTTATTTT TAGAATTCTC 2640
CCCAGCTAAA GAAAAACCCA TATAGTTAGT TTGTCGTTAT AGATACTTAG GTTAAGCTCA 2700
GTGTGTCCGT CTTGTTCACA GACGCGTTGT GTCTTTGGGA AGAATAAATC AGATCTATCG 2760
CCTACTCATT
2771Nucleotide Fasta Sequence
>FBpp0075701|Bromodomain|Drosophila melanogaster
ATCATTGCGCACAGCAAGTGGGCAAACTCGTTGTATCGCTTGTGAAATTTAAGGAAAAGTACACTTTGTTCAAAACTAACGAAGAGAATCGCAATATCTGCCGATCTTGGAATGTCTGGTGGTCCATCCATAACGATAAAAAGCCAACCAATCGATGGTAACAACACGGGCAACGCTGCGGCGCAACAGCAGCAGCAGGCAGCGAATGGCGCAGCAACCGCTGGTGCATCTGGAGCCGCTGGCAGCGCCCAGAATCCAGGACACGGAGGAGCTGCGTCCGGCGCTGGCAGTGTGCCGGCAGAGGGAACGCGCCAGAACAGCCTACAGCGCATTCAGCAGCGAAAGCAAAAGGTCTTCAATCTGCCCGTGCCACAGAAACTGGCCAAATTGTCGATGTATTCCGCCTGCCAGTCTGAGGGATGCCGTTGCACCGGCTGGAAGACACCGCAGGAAAATCGCCACCGTGACGTCGAGTCCTCCTACTGTCCGGAGTTCAACGAGGAGTGCCGCAACACCAGCTGTCGCCATTCGCTGAGATCGCACATAGCCCATCTGGACAATATATCCAGTTCCAGCATGAACGAGCTACTGGGCGCCATTATAGACATGGAGAACCTATTCATGTCCATGCAGCGCGTCGAGGACGAGGACACCAAGAAGGTGTACCAGTACCTCTTCCGTTTGCTGCGCCAGTGCGTCCTCACGCGCCAGCAGGCGGTCATCCGGGGTCCTCTCGGCGATCCACCATTCGAGACGCCGTGCATCACCAAGGCTGTGCTCTCGTTGGTCTTCTACAAGTACAATCACCTGAGCACGCCTGAACTCCAAACCATGACCGAGGTGGCCAAGACGTTCTTGAACTTTCTGAACCACTACAACTTTGAATCGCCGTCGACCAGGAGAGGAGATCTCACCCACGAGGATGCCTCTAACTACAAAATCAACTACACCAGGTGGTTGGTGTTCTGCCACGTGCCCGCCTTCTGTAACTCCCTGCGCCAATGTGAAACGTCCCTAGTGTTTGGACGAACGCTCCTGCGCACCGTTTTCCAGTGCATGTCGCAGCAGCTGAAAAAGAAGTGCATCTCCGAGCGGGATCGCTTTCCCGAGGACAAGCGTTCGATCATCACGCTGATGCCGAAGTTTTTGGAAACGCTTCGCGCCGAATTGCTCAAGGATGATTCGCCCATCTGGGATACCAGCTACCGCCCGTCAAATTCCTTTGTCATCCAGCAGAGAAAGCGTAACCAGGAGGTGGCAAATGTACCCATTGGTCCCAGTGCAGCAAGCATTGGTGGAAACAAGAGGACCAGTGTGGGTGAACCGCTCCACAAGCGAATCAAAAAGGAGCCCACCGATCGTCCAAGCAGTGAGAATTTGGATGACCTGCCTGCGGATGTAGTAATGCGCGCCATGAAATCGGTGTCCGAGTCGAAGACCACCAACAAAGCGGAAATTCTCTTTCCGGTTAATGTGTCGCGGGATGAGAACGTCAAGGCGGAGGAGCAGAAGCGAGCCATTGAGTTCCATGTGGTGGGCAATTCGCTGACCAAACCGGTGGACAAGCAGACTGTTTTGTGGCTACTGGGCCTGCAGCTCGTATTTGCCTATCAGCTACCCGAGATGCCGCGCGAGTACATCAGCCAGTTGGTTTTCGACACCAAGCACAAAACACTGGCGCTCATCAAGGAAAACCAACCCATCGGCGGCATCTGTTTCCGCCCGTTTCCGTCGCAAGGCTTCACCGAGATCGTTTTCTGCGCGGTCACCATGTCGGAACAAGTTAAGGGCTATGGCACGCACTTGATGAACCACTTGAAGGACTACAGCATACAGAGGGGTATCAAGCATCTGCTCACATTCGCCGATTGCGATGCCATCGGGTACTTCAAGAAGCAGGGTTTCTCCAAGGACATCAAATTGGCGCGACCAGTTTATGCGGGCTACATCAAGGAGTACGATAGTGCTACTCTCATGCACTGCGAGCTGCATCCAAGCATTGTGAACACGCAGTTCATAGCTGTAATTCGCAGTCAGAGCGAGATTCTGAAGGAGCTGATCGCACAGCGCCACAACGAGGTGCAGAAAGTAAGACCCGGCTTGACTTGCTTCAAGGAGGGCCTGCCCGTGATTCCCGTGGAATCGATTCCTGGTCTGCGGGAGATCGGTTGGAAGCCGCAAAATCGTCCGGCGCGCTCATCGCGACCCCTCGAGGAATCCACCGATCCGGAGAAGCTGGCCACGTCCTTTGCATCCGTGCTGCAATCCGTGCGCCAGCACACCACCGCCTGGCCCTTCCTGCGCCCGGTGACCGCGGCCGAAGTTCCGGACTACTACGATCACATTAAATATCCCATGGACCTGAAGACCATGGGCGAGCGCCTGAAGAAGGGTTACTACCAAACGCGCCGCCTGTTCATGGCGGACATGGCGCGCATTTTCTCCAACTGTCGGTTCTACAATTCGCCCGACACCGAGTATTATCGGTGTGCCAACTCCCTGGAGCGCTACTTCCAGACCAAGATGCGCGAGCTGGGGCTGTGGGACAAATGATGCAGTGATTCCGAGGAGCCCTGCATAAGGCCGAACATTTAATCGAACTAAATTATTATATTAATTCTATTTATTTTTAGAATTCTCCCCAGCTAAAGAAAAACCCATATAGTTAGTTTGTCGTTATAGATACTTAGGTTAAGCTCAGTGTGTCCGTCTTGTTCACAGACGCGTTGTGTCTTTGGGAAGAATAAATCAGATCTATCGCCTACTCATT
|
| Sequence Source |
Ensembl |
| Keyword |
KW-0012--Acyltransferase
KW-0103--Bromodomain
KW-0181--Complete proteome
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0808--Transferase
--
|
| Interpro |
IPR016181--Acyl_CoA_acyltransferase
IPR001487--Bromodomain
IPR018359--Bromodomain_CS
IPR000182--GNAT_dom
IPR016376--Hist_acetylase_PCAF
IPR009464--PCAF_N
|
| PROSITE |
PS00633--BROMODOMAIN_1
PS50014--BROMODOMAIN_2
PS51186--GNAT
|
| Pfam |
PF00583--Acetyltransf_1
PF00439--Bromodomain
PF06466--PCAF_N
|
| Gene Ontology |
GO:0005671--C:Ada2/Gcn5/Ada3 transcription activator complex
GO:0005634--C:nucleus
GO:0005700--C:polytene chromosome
GO:0005703--C:polytene chromosome puff
GO:0000124--C:SAGA complex
GO:0003682--F:chromatin binding
GO:0010484--F:H3 histone acetyltransferase activity
GO:0010485--F:H4 histone acetyltransferase activity
GO:0004402--F:histone acetyltransferase activity
GO:0007412--P:axon target recognition
GO:0006338--P:chromatin remodeling
GO:0048813--P:dendrite morphogenesis
GO:0016573--P:histone acetylation
GO:0043966--P:histone H3 acetylation
GO:0043967--P:histone H4 acetylation
GO:0007517--P:muscle organ development
GO:0006355--P:regulation of transcription, DNA-templated
|
| Orthology |
|
| Created Date |
25-Jun-2016 |
