WERAM Information

Tag Content
WERAM ID WERAM-Art-0010
Ensembl Protein ID AT1G14510.1
Uniprot Accession Q8LA16; ALFL7_ARATH; Q9M9R2; Q9MA31
Genbank Protein ID NP_172903.1
Protein Name PHD finger protein ALFIN-LIKE 7
Genbank Nucleotide ID NM_101318.3
Gene Name ALFL7;AL7At1g14510;F14L17.29;T5E21.1
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
AT1G14510 AT1G14510.1 AT1G14510.1
Details
Type Family Domain Substrates AA References (PMIDs)
Me_Reader PHD PHD-type H3K4me3/2 K 19154204
Status Reviewed
Classification
Type Family E-value Score Start End
Me_Reader PHD 1.40e-13 51.6 197 246
Organism Arabidopsis thaliana
NCBI Taxa ID 3702
Functional Description
(View)		 Histone-binding component that specifically recognizes H3 tails trimethylated on 'Lys-4' (H3K4me3), which mark transcription start sites of virtually all active genes.
Domain Profile
  Me_Reader PHD
      PHD.txt   3 iClvCgkddegekemvqCdeCddwfHlkCvklplsslpegkswyCpsCke 52 
                  +C +Cg+++ g++++++Cd C++wfH+kCvk++  +++  k++ CpsC++
  AT1G14510.1 197 VCGACGDNYGGDEFWICCDACEKWFHGKCVKITPAKAEHIKHYKCPSCTT 246
                  8********************************555554479******97 PP
Protein Sequence
(Fasta)		MEGIQHPIPR TVEEVFSDFR GRRAGLIKAL STDVQKFYHQ CDPEKENLCL YGLPNETWEV 60
NLPVEEVPPE LPEPALGINF ARDGMQEKDW ISLVAVHSDS WLISVAFYFG ARFGFGKNER 120
KRLFQMINDL PTIFEVVTGN AKQSKDQSAN HNSSRSKSSG GKPRHSESHT KASKMSPPPR 180
KEDESGDEDE DDEQGAVCGA CGDNYGGDEF WICCDACEKW FHGKCVKITP AKAEHIKHYK 240
CPSCTTSKKM KA 252
Nucleotide Sequence
(Fasta)		CTCAAATTGT CTTTTGTCTC CTTTCCTTTT CGTTTTTAGG GTTTTTTTTT CTTAGCACAG 60
CTCTCTCTTC TCAATTTCCC CAAATGAAAT AAATTCCTCC GAAAGTTTAT AGATTTCACT 120
CTCCCCCGAA CTATACAAAA TTCCCTCAAA AGGAAAAACT AAAAAGCCGA TCTTGGCTTT 180
TTTGTTTCTG AGTGCATCTC GATACTTGGA AGCATTCTTT GGTGAGGCTG ATTCATTCTC 240
ATCTGTGAAA GTCTTTGGCT TTTGAAGCAA TACTATGGAA GGAATTCAGC ATCCTATACC 300
TCGCACTGTC GAAGAGGTTT TTAGCGACTT TCGTGGTCGT AGAGCTGGTC TCATCAAGGC 360
TCTCTCTACT GATGTACAGA AGTTTTACCA TCAGTGTGAC CCTGAGAAGG AAAACTTGTG 420
TCTTTATGGA CTTCCAAATG AGACATGGGA GGTTAATCTT CCCGTTGAGG AGGTCCCTCC 480
TGAGCTTCCT GAACCAGCGT TAGGCATCAA TTTCGCAAGG GACGGAATGC AAGAAAAAGA 540
CTGGATTTCT TTGGTTGCAG TTCACAGTGA TTCATGGCTT ATCTCTGTTG CATTTTACTT 600
TGGTGCACGT TTCGGATTTG GCAAGAATGA GAGGAAGAGG CTCTTCCAGA TGATAAATGA 660
TCTCCCAACC ATTTTCGAGG TTGTAACTGG CAATGCAAAG CAATCCAAGG ATCAATCTGC 720
TAACCACAAC AGTAGCAGAA GCAAATCTAG TGGTGGCAAG CCTCGTCATT CTGAATCTCA 780
CACTAAGGCT TCAAAGATGT CCCCTCCACC AAGAAAAGAA GATGAGAGCG GAGATGAGGA 840
TGAAGATGAC GAGCAAGGTG CTGTTTGTGG TGCGTGTGGC GACAACTATG GAGGAGATGA 900
GTTCTGGATA TGTTGTGATG CTTGCGAGAA ATGGTTCCAT GGGAAATGCG TGAAGATCAC 960
ACCAGCAAAG GCTGAGCATA TCAAACATTA CAAATGCCCA AGTTGCACTA CCAGCAAGAA 1020
AATGAAAGCC TGAAAGTGAT AATAACATTA GAGCCTGTGA AAGAGGAAAA CGTTTTCACA 1080
GTTTAAGAAG ACAGTACAAG AGTTTAGCTG TGGGAAGAAG AAGAAACAAA AGGCTTCTGA 1140
TTGCGTAGTT TTAATGGGAT TGAGACAGCT TACAGTTAGT AATGTCTCTT TCTCTTTTCT 1200
TTTCTTTTTT TTTGCTGTTA ATGTTAAAAT GTTATGACTA ATTTGTCTTA AGTTTCTGAG 1260
AAAATTCTGT CTTTTAAGCA CTCTCTAGTC TATGTCAAGT GGTTTCTTCT TCTCGGTA 1319
Sequence Source Ensembl
Keyword

KW-0156--Chromatin regulator
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0539--Nucleus
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0804--Transcription
KW-0805--Transcription regulation
KW-0862--Zinc
KW-0863--Zinc-finger
--
Interpro

IPR021998--Alfin
IPR019786--Zinc_finger_PHD-type_CS
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD
PROSITE

PS01359--ZF_PHD_1
PS50016--ZF_PHD_2
Pfam

PF12165--DUF3594
PF00628--PHD
Gene Ontology

GO:0005634--C:nucleus
GO:0035064--F:methylated histone binding
GO:0008270--F:zinc ion binding
GO:0016568--P:chromatin modification
GO:0006355--P:regulation of transcription, DNA-templated
GO:0006351--P:transcription, DNA-templated
Orthology
WERAM ID Ensembl Protein ID Species Identity E-value Score
WERAM-Arl-0043 fgenesh2_kg.1__ 1579__ AT1G14510.1 Arabidopsis lyrata 97 7e-113 403
WERAM-Brr-0085 Bra016698.1-P Brassica rapa 89 5e-104 374
WERAM-Bro-0146 Bo8g066080.1 Brassica oleracea 88 9e-103 370
WERAM-Glm-0084 GLYMA07G40165.1 Glycine max 82 8e-99 357
WERAM-Prp-0081 EMJ24886 Prunus persica 80 1e-95 346
WERAM-Pot-0035 POPTR_0003s04070.1 Populus trichocarpa 80 2e-95 345
WERAM-Met-0117 KEH32736 Medicago truncatula 77 5e-94 341
WERAM-Thc-0075 EOY26404 Theobroma cacao 79 1e-93 340
WERAM-Viv-0077 VIT_12s0035g01980.t01 Vitis vinifera 78 6e-92 334
WERAM-Sol-0017 Solyc01g102750.2.1 Solanum lycopersicum 77 2e-89 325
WERAM-Sot-0055 PGSC0003DMT400047018 Solanum tuberosum 77 7e-89 323
WERAM-Mua-0059 GSMUA_Achr3P16750_001 Musa acuminata 73 1e-85 313
WERAM-Amt-0088 ERM99796 Amborella trichopoda 69 5e-84 308
WERAM-Lep-0110 LPERR11G07220.1 Leersia perrieri 71 8e-84 307
WERAM-Orbr-0121 OB11G16440.1 Oryza brachyantha 71 9e-84 306
WERAM-Ors-0103 OS11T0244800-01 Oryza sativa 71 2e-83 306
WERAM-Orr-0116 ORUFI11G08380.1 Oryza rufipogon 71 2e-83 306
WERAM-Orni-0115 ONIVA11G08290.1 Oryza nivara 71 2e-83 306
WERAM-Orm-0100 OMERI11G06990.1 Oryza meridionalis 71 2e-83 306
WERAM-Ori-0116 BGIOSGA034217-PA Oryza indica 71 2e-83 306
WERAM-Orgl-0111 OGLUM11G07920.1 Oryza glumaepatula 71 2e-83 306
WERAM-Org-0108 ORGLA11G0071500.1 Oryza glaberrima 71 2e-83 306
WERAM-Orb-0115 OBART11G08090.1 Oryza barthii 71 2e-83 306
WERAM-Orp-0107 OPUNC11G07880.1 Oryza punctata 71 2e-82 302
WERAM-Sob-0083 Sb05g007010.1 Sorghum bicolor 72 5e-81 297
WERAM-Sei-0086 Si023009m Setaria italica 67 9e-81 296
WERAM-Brd-0098 BRADI4G21040.1 Brachypodium distachyon 71 2e-80 295
WERAM-Zem-0014 GRMZM2G016817_P02 Zea mays 66 2e-79 292
WERAM-Hov-0037 MLOC_37761.1 Hordeum vulgare 64 2e-76 282
WERAM-Aet-0106 EMT19247 Aegilops tauschii 64 3e-76 282
WERAM-Orl-0063 KN539254.1_FGP005 Oryza longistaminata 70 1e-75 280
WERAM-Tra-0353 TRAES3BF138600040CFD_t1 Triticum aestivum 67 5e-75 278
WERAM-Sem-0105 EFJ23237 Selaginella moellendorffii 64 1e-71 266
WERAM-Php-0091 PP1S38_137V6.1 Physcomitrella patens 63 4e-71 265
Created Date 25-Jun-2016