WERAM Information

Tag Content
WERAM ID WERAM-Drm-0002
Ensembl Protein ID FBpp0072421
Uniprot Accession Q9W0T1; NU301_DROME; Q4V464; Q7KVD8; Q95VB8; Q960Y3; Q9W0T2
Genbank Protein ID NP_001163304.1; NP_001261190.1; NP_728505.1; NP_728507.1; NP_995946.1
Protein Name Nucleosome-remodeling factor subunit NURF301
Genbank Nucleotide ID NM_001169833.2; NM_001274261.1; NM_167817.3; NM_167819.3; NM_206224.3
Gene Name E(bx);CG32346;CG7022;Nurf301
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
FBgn0000541 FBtr0072521 FBpp0072421
FBgn0000541 FBtr0072522 FBpp0072422
FBgn0000541 FBtr0301348 FBpp0290562
FBgn0000541 FBtr0332102 FBpp0304412
FBgn0000541 FBtr0332103 FBpp0304413
FBgn0000541 FBtr0332104 FBpp0304414
Details
Type Family Domain Substrates AA References (PMIDs)
Ac_Reader Bromodomain Bromodomain H4K16 K 19629165
Status Reviewed
Classification
Type Family E-value Score Start End
Me_Reader PHD 2.20e-28 98.8 341 2545
Ac_Reader Bromodomain 3.80e-23 81.9 2575 2643
Organism Drosophila melanogaster
NCBI Taxa ID 7227
Functional Description
(View)		 Histone-binding component of NURF (nucleosome remodeling factor), a complex which catalyzes ATP-dependent nucleosome sliding and facilitates transcription of chromatin. Specifically recognizes H3 tails trimethylated on 'Lys-4' (H3K4me3), which mark transcription start sites of virtually all active genes. Required for homeotic gene expression, proper larval blood cell development, normal male X chromosome morphology, ecdysteroid signaling and metamorphosis.
Domain Profile
  Me_Reader PHD
      PHD.txt   3 iClvCgkddegekemvqCdeCddwfHlkCvklplsslpegkswyCpsCke 52 
                   C+vC ++  +   +++C++C+  +Hl+Cv++p++ +p + +w C  C+ 
  FBpp0072421 341 HCRVC-HRLGD---LLCCETCPAVYHLECVDPPMNDVPTE-DWQCGLCRS 385
                  79***.44444...8***********************99.9******96 PP
      PHD.txt    3 iClvCgkddegekemvqCdeCddwfHlkCvklplsslpeg.kswyCpsCke 52  
                   +C+ C+++++++k+ v Cd C++wfH++Cv+++ ++++++ ++++C  Ck+
  FBpp0072421 2441 YCI-CRTPYDDTKFYVGCDLCSNWFHGDCVSIT-EEASKKlSEFICIDCKR 2489
                   8*9.*****************************.555555489******96 PP
      PHD.txt    3 iClvCgkddegekemvqCdeCddwfHlkCvklplsslp.egkswyCpsCke 52  
                   +C  C+++++++++ ++Cd+C+dwfH++Cv++ +s+++  + +++Cp+C++
  FBpp0072421 2497 YCS-CRQPYDESQFYICCDKCQDWFHGRCVGILQSEAEfID-EYVCPECQR 2545
                   8*9.*****************************88888666.*******97 PP
  Ac_Reader Bromodomain
    BROMO.txt    3 hevsepFrepvdpqleipdYydiikePmdLstikerleegnYsspeefvkDvrlifnNakaynenkssvq 72  
                   h+ ++pF+epvdp +e+pdYy++ikePmdL+ ++ +le++ Y++++ef+ D+  if+N++ yn+++ss++
  FBpp0072421 2575 HKSAWPFMEPVDP-KEAPDYYKVIKEPMDLKRMEIKLESNTYTKLSEFIGDMTKIFDNCRYYNPKESSFY 2643
                   899**********.7***************************************************9976 PP
Protein Sequence
(Fasta)		MSGRGSRKRG RPPKTPNERA SGRFNYQLLK KPKYLSEGKS QPSTPSASRG ISPQSDEGSR 60
SSHNNHTNRS RGSAAKRGRG RKSAVQPNTS SYSGRKGYES EYHYGSDFGD SEEDKSDNED 120
DMLLTPSDDE SLEVANESES EFSVCSFNQN GVGRPPRPPS PEPVWLQEGR QYAALDLPDS 180
SEDLFIANTH VLRALSIYEV LRRFRHMVRL SPFRFEDLCA ALACEEQSAL LTEVHIMLLK 240
AILREEDAQG THFGPLDQKD TVNISLYLID SITWPEVLRS YVESDKTFDR NVFHILSHTE 300
YPYTGIDNRL EVLQFLSDQF LTSNSIRDVM LQEGPIHYDD HCRVCHRLGD LLCCETCPAV 360
YHLECVDPPM NDVPTEDWQC GLCRSHKVSG VVDCVLPQEK QGVLIRHDSL GVDRHGRKYW 420
FIARRIFIED QENFTCWYYS TTSKLKLLLS RLDAEELETR LHSQITERRD EIERQMKLTE 480
TLTNEHKHTK RSVIEIEQEA KNELLEKEVL DEDEKDGDAK SESQSIEGTK KQEECKMVTR 540
QKSNQLTNGT LHFKLGMEQG FKNYVNQYST NPIALNKPQR NEERDKRRHL SHKFSLTTAS 600
DFKWIGITMG TTDNMITTLR QTLINFESNI AASFLNINWV VNKKIWNAAV MNARRPSEFA 660
VVLLLFQASL KSVVFANVWH EQLGHTTLQR ITSAEREERK KLEKREKRER DDEEERNRLA 720
FNYIKYTLGL KHQVWKQKGE EYRVHGQWGW LWLSSSRRCG VRARRAQPLT HNRVYVHYTM 780
GEENDVNEII LVDPRTQRFM QQCESSNVDG QVCHYLPDQY KNVKVIEDVT EKIKGHIDVS 840
KALNAPGRTY YSKVARKSRL DDLLDRRLKL AEVEEQMASK IPSDMKPLLV SSQNNTANSK 900
QTFLEKRLLR LTEVQAKGGP ANVNLELVNS LAKQIQTVRL QFSQLNRFAK VFRCYTKECN 960
TNSNAVSQIT QNTCYSPLCL QKARAKKELL LLLRKAHTAG NGSKETVAAI LGAVKKPSIL 1020
EQKLTEGKRE STQVAVDDSE EGKPAESEAP LDLLQDWEHA RAHAVPFSDS LLTECILVDQ 1080
ECVTNTKIKQ EVNASSGCNT TPDSNTQDSD KIDYIESMDV CSNVEIESTE DSIVTGLNSG 1140
NAEDVDMTPG WRRKRNQKSK KSYIGTKDVL DQTLDKDIPL NKQNRRFPIT ARPVKRECVK 1200
KYERETFENG NERVYSTSSP RGRVYLLNDA AKLYEQAVKT EDKSTITKKP SYSRYPLISN 1260
FLTHKKKRSL LVLPRFELLK LARLGGKSST NGFHHAAKNN TIWQYQCSRP LFRTCWSYRT 1320
SNATSLSSLA LQLRILWSCL RWDDMIAKPP STDGKHQVTT DTEIVTLELL KLRHSGRYGE 1380
KTSYLRRKVV IPLEMPKTVR EVTSIRSGLR KRKRAESPQP TEPQITEEWV DEDKLELWEI 1440
KFMGEKQEKA RLSAVTRSVA SRQLEASGSN GSNTSTNGAL GVAGRVQLAP KLSEDVKEKM 1500
EQQLKLQRAV HQQRKLVATG EITRSVTPVK GQVIGSRRVI VKNPDGTTRI IQQAVTQVSR 1560
TGGANTAAAA ASPTVGGSTS TQSNPSTSTP HKVQIIRGPD GKVSVRGLNP GQQLVQMPDG 1620
KLHVLTTTTS SNSAGQGNKM KVPIKPASTS SSPAISSAQT TTNPVTPVIK QIAVKHVTKN 1680
SATQSIASSS RVALPLAQIK NKLLLAQQQQ QSTSSSPATS SSPVQKIVSK VVNTSTSGQT 1740
LQQVFVQSGS KLVVGQNAQG QKVIISTSAA QQQGTSPVQQ QQLVQSQPIQ QSPQQISMTQ 1800
VGNQPTQKVI QQIVNTSNVQ QQIVVGGQRI ILSPGQTIVT QRNVPQSQAL QMVQQQIQTQ 1860
QQQQQHHVVQ PQQQFVVQSN QIVQSSPSAQ TKLVKQLVVQ QQSQQTIEEK TQITTTDSNE 1920
TGTQQVLVPN STLAQQLAQG KLQVATVNGQ QVIVKPLGNN QAQIVAHIKH QGDGNAHIVT 1980
SNSATAVPQA NPQTSPVKQQ ALPPQSPQQV VVQQQQIHQQ SPTNFESGVT PITQQPVLTQ 2040
AVQAPAQQQA LSVEESLLQN QPPGTVIKCV TAQVLQTEHG PRIVLQGLVG NDFTAQQLQL 2100
VQTQVKQQLM KAQESNGKLG VLGPTKIYLA VQPENAVQSQ PPPLTPVHQS AAHQQTNNIE 2160
IDADTLATTY EANSTIKDIA INNGDDQENS KCAETENSNI TTNESFAGTS SLLEGSEHDE 2220
PTNLAGLDIS ETDLENKQNE SFVVTRGYIQ KSISNALKQG NLSPELEEKL VCMQKQQENA 2280
NSTNEWETCS RGSVNEEALT PSRQTDDTEW KIRTSLRRPN AMTTSSQFNR ILKKNRSKND 2340
EVAELGEQKQ SQLERHKELL KKNILRKRSL LERNLQSEIH EDVKTKVQRH VRPLSNASPD 2400
EQSENERSGE PNLDFKRTEV QNPRHGAGRP KKLTRKKEKL YCICRTPYDD TKFYVGCDLC 2460
SNWFHGDCVS ITEEASKKLS EFICIDCKRA RETQQLYCSC RQPYDESQFY ICCDKCQDWF 2520
HGRCVGILQS EAEFIDEYVC PECQRKNDAN AANMKKLTSN DVEELKNLIK QMQLHKSAWP 2580
FMEPVDPKEA PDYYKVIKEP MDLKRMEIKL ESNTYTKLSE FIGDMTKIFD NCRYYNPKES 2640
SFYKCAEALE SYFVQKIKNF RENVFDQRT 2669
Nucleotide Sequence
(Fasta)		TAGCTATGTT CAAAACTGTA ATGTTAGGTA AAAGTCTCTT TCGCAGTGTG CTGAAGATAG 60
TTAAAAATAT TAGAATATAT CGTGTTAAAT CCTGTGCAAT TATTCCGCAA CATGCTGGGT 120
AATTTGCGCA GTTAATCCAT GTGTTAATTG TGAAAGAAGA GTGACATTTA AACAGACGCA 180
AAAATTTTCA CGGTTGCTTA AATGGCGGAC AATGTGCGTT GGCTTCATTT CATCGCACTC 240
GCACACATAC AATCGAACTT GGTGGTGCTG TCCAGTGCGT TTGCCGTCCA ACACTAGAAG 300
CCAAGAATGT GTTTTGAATA CATGTACTTA ATGTATTTAA TCGGAACCGT TATTCTGAAC 360
TAAACAAGCT CTTTTGGCGG GTTTTTTTCA ACTCCAAATT TGCGCAATAC AAAGAAAGTG 420
AACACCCAAC GACAAACTTT TGACGATCTG ATCGATTTTT CCCCCACATA CGCTGTTGAG 480
TAAATGTGTG TTTGAATGTG CCCCGTAAAT ACATAGCTAG CTGAGTGCGA ATCTAATGTG 540
CAGCCTCGCA GCATTAACTT GGAACAATAT CTGAGGAGAG TACCCCCACG CACCCCTGCA 600
CACAGCCAGA TAAATACGCA AGGCGAAAAC AAACAAGATG AGCGGTCGCG GCAGCCGTAA 660
ACGTGGACGT CCGCCAAAGA CGCCCAACGA ACGCGCATCA GGACGCTTCA ATTACCAGCT 720
TCTCAAGAAG CCGAAGTATC TCAGCGAGGG AAAGTCGCAG CCCAGCACTC CGTCGGCATC 780
CAGGGGCATT TCTCCACAGA GCGACGAGGG CAGCAGGAGC AGCCACAACA ACCACACCAA 840
TCGCAGTCGC GGGAGCGCCG CTAAGAGGGG ACGAGGCCGC AAATCCGCCG TGCAACCGAA 900
CACCAGTAGC TACTCTGGAA GGAAAGGGTA CGAGTCGGAG TATCACTACG GGTCAGATTT 960
TGGGGATTCC GAAGAAGATA AATCCGATAA TGAGGATGAT ATGCTGCTTA CTCCCAGCGA 1020
CGACGAGAGC CTAGAAGTAG CCAACGAGAG CGAATCAGAG TTTTCCGTGT GCAGCTTTAA 1080
CCAAAATGGA GTTGGTCGGC CGCCACGTCC TCCTAGCCCA GAACCTGTGT GGCTGCAGGA 1140
AGGTCGTCAG TATGCAGCGC TTGATTTGCC GGACTCGTCG GAGGATCTTT TCATTGCTAA 1200
TACACACGTT TTGCGCGCGC TAAGTATCTA TGAAGTACTG CGACGATTTC GCCACATGGT 1260
CCGCCTTTCA CCATTCCGAT TTGAAGACTT GTGTGCAGCG CTGGCTTGTG AGGAGCAAAG 1320
TGCATTATTG ACGGAGGTAC ACATAATGCT GCTTAAAGCG ATTCTTCGAG AAGAGGACGC 1380
GCAGGGTACA CATTTTGGCC CGCTGGATCA AAAAGATACG GTTAATATAA GTCTTTACCT 1440
GATTGACTCT ATAACGTGGC CGGAAGTTTT GCGAAGCTAT GTAGAAAGCG ATAAGACATT 1500
TGATCGCAAC GTGTTTCACA TTTTAAGCCA CACTGAATAC CCTTACACGG GCATTGACAA 1560
CCGGCTTGAA GTGCTCCAGT TTCTGTCAGA TCAATTTTTA ACTTCCAATT CTATACGAGA 1620
TGTAATGCTG CAGGAGGGAC CTATTCATTA TGATGACCAT TGCCGAGTGT GCCATCGGCT 1680
CGGTGATTTA TTATGTTGCG AGACGTGCCC TGCTGTCTAT CATTTGGAAT GTGTAGACCC 1740
GCCAATGAAT GACGTACCTA CTGAGGATTG GCAGTGCGGG CTTTGCCGCT CGCATAAGGT 1800
AAGTGGCGTA GTGGACTGCG TGTTGCCACA AGAAAAACAA GGCGTGCTAA TCCGGCATGA 1860
TAGCCTCGGT GTTGATCGTC ATGGGCGCAA ATATTGGTTT ATTGCACGTC GCATTTTTAT 1920
CGAGGATCAG GAGAACTTTA CATGCTGGTA TTACAGTACG ACAAGTAAGT TAAAATTGCT 1980
GCTCAGTCGA CTGGACGCCG AAGAACTGGA AACTCGTCTG CATAGCCAGA TTACAGAAAG 2040
GAGAGACGAA ATCGAGCGCC AAATGAAACT GACTGAGACC TTAACCAATG AACACAAACA 2100
CACGAAGCGT AGTGTTATCG AAATCGAACA AGAGGCTAAA AATGAACTTT TGGAGAAAGA 2160
GGTGCTTGAC GAGGATGAAA AAGATGGTGA TGCTAAATCT GAGAGTCAAT CTATAGAGGG 2220
AACAAAAAAA CAAGAAGAAT GTAAAATGGT CACGCGTCAA AAATCCAATC AGCTGACTAA 2280
TGGTACTTTG CATTTTAAAC TTGGCATGGA GCAAGGATTT AAGAACTATG TCAACCAGTA 2340
TTCAACAAAT CCAATTGCAC TCAACAAGCC GCAACGAAAC GAGGAGCGAG ATAAGCGACG 2400
CCATCTGTCC CATAAGTTCT CGTTAACGAC GGCTTCTGAC TTTAAATGGA TCGGTATAAC 2460
CATGGGAACT ACTGACAATA TGATAACAAC TCTAAGGCAA ACATTGATAA ACTTCGAATC 2520
CAATATAGCA GCTTCCTTTT TAAATATTAA CTGGGTAGTT AACAAAAAAA TTTGGAATGC 2580
TGCGGTGATG AACGCCCGTC GACCTTCTGA ATTTGCGGTA GTATTGTTAC TTTTTCAAGC 2640
GTCCCTTAAG AGCGTTGTTT TTGCCAACGT CTGGCATGAG CAACTCGGAC ACACAACTTT 2700
GCAACGCATA ACTAGTGCCG AACGAGAGGA GCGAAAAAAA CTAGAAAAGC GAGAGAAGCG 2760
CGAGCGGGAT GATGAGGAAG AACGTAATCG CTTAGCATTT AACTACATAA AGTATACCCT 2820
GGGTCTCAAA CATCAAGTCT GGAAGCAAAA AGGAGAAGAA TACCGGGTCC ACGGGCAATG 2880
GGGCTGGCTT TGGCTCTCAA GCAGTCGACG CTGTGGTGTT CGTGCACGTC GAGCCCAACC 2940
TCTAACACAC AATAGAGTCT ACGTACATTA CACCATGGGA GAGGAAAACG ACGTAAATGA 3000
AATTATTTTA GTCGACCCAC GCACCCAACG GTTTATGCAA CAATGTGAGT CAAGCAATGT 3060
CGATGGTCAG GTGTGTCATT ATTTACCGGA CCAATATAAA AATGTGAAAG TTATAGAAGA 3120
TGTTACGGAG AAAATCAAAG GGCACATCGA CGTCAGCAAA GCGCTAAATG CTCCAGGCCG 3180
TACTTATTAT TCAAAAGTGG CTCGCAAATC TAGATTAGAT GACTTATTGG ATCGCCGTTT 3240
AAAGTTGGCC GAGGTCGAGG AGCAGATGGC TTCTAAAATT CCTTCTGATA TGAAGCCGCT 3300
TCTTGTTTCT TCCCAAAATA ATACAGCCAA CAGCAAACAA ACGTTTCTAG AGAAGCGTTT 3360
ACTTCGCCTT ACTGAAGTCC AAGCAAAGGG GGGTCCTGCA AACGTAAACT TGGAACTTGT 3420
TAATTCGCTG GCTAAACAAA TTCAAACCGT GCGCTTACAA TTTAGTCAGC TTAATCGATT 3480
TGCTAAAGTT TTTCGTTGTT ATACAAAGGA GTGTAACACC AATTCAAATG CTGTCTCTCA 3540
AATAACCCAA AATACTTGCT ACTCTCCCTT ATGTCTTCAA AAAGCTCGGG CCAAAAAAGA 3600
ACTTCTTTTG TTGTTACGAA AGGCGCATAC TGCCGGTAAT GGCTCAAAAG AGACAGTTGC 3660
CGCTATTTTG GGCGCTGTTA AAAAGCCATC TATTCTCGAG CAGAAGCTGA CGGAGGGTAA 3720
AAGAGAATCC ACTCAGGTGG CCGTGGATGA TTCTGAAGAG GGGAAGCCAG CTGAATCCGA 3780
AGCGCCGTTG GATTTACTTC AAGATTGGGA ACATGCACGA GCGCACGCCG TTCCTTTTAG 3840
CGATTCTTTA TTGACCGAAT GCATCCTGGT TGACCAGGAG TGCGTAACCA ACACGAAAAT 3900
TAAACAAGAG GTGAATGCCA GTTCCGGATG CAATACAACT CCTGACTCGA ACACACAAGA 3960
CTCCGATAAA ATAGACTATA TTGAGAGTAT GGACGTTTGT AGTAATGTTG AAATTGAGAG 4020
TACCGAAGAT TCCATTGTTA CGGGCTTAAA CTCTGGTAAC GCTGAAGATG TCGATATGAC 4080
ACCTGGATGG CGGCGAAAGC GTAACCAGAA ATCGAAAAAA AGCTACATCG GCACTAAAGA 4140
TGTGTTGGAT CAGACGTTAG ACAAGGATAT ACCACTTAAC AAACAGAACC GCAGATTTCC 4200
TATTACTGCA CGTCCGGTTA AGCGCGAATG TGTCAAAAAA TACGAACGAG AGACATTTGA 4260
GAATGGAAAC GAGCGGGTCT ATTCGACTAG TTCACCTCGG GGTCGTGTAT ACCTCCTTAA 4320
TGATGCGGCC AAGTTGTATG AGCAAGCTGT CAAAACTGAG GATAAGTCAA CGATAACTAA 4380
AAAGCCATCA TACTCTCGGT ATCCACTTAT ATCCAATTTT CTTACTCATA AAAAAAAGCG 4440
TAGCCTTTTA GTGCTACCAC GATTTGAGCT CCTGAAGCTG GCTCGTCTGG GTGGAAAATC 4500
ATCGACAAAT GGTTTTCATC ACGCTGCGAA AAATAACACA ATTTGGCAGT ATCAGTGCTC 4560
GCGTCCCCTC TTCCGAACCT GCTGGTCCTA CAGAACATCT AATGCCACGT CCTTATCCAG 4620
CCTAGCACTT CAGCTTCGAA TATTGTGGTC GTGTCTCCGC TGGGATGACA TGATAGCAAA 4680
GCCCCCATCC ACGGATGGGA AGCATCAGGT TACTACGGAT ACTGAAATTG TAACATTGGA 4740
ATTGCTCAAA CTTCGGCACT CAGGACGCTA TGGTGAAAAA ACAAGCTATT TGCGACGAAA 4800
AGTTGTTATT CCACTTGAAA TGCCGAAGAC TGTAAGAGAA GTAACATCCA TACGGTCCGG 4860
ACTGCGAAAA CGAAAGCGTG CTGAATCTCC TCAGCCAACC GAGCCACAAA TTACCGAGGA 4920
ATGGGTCGAC GAAGATAAAT TGGAGTTATG GGAAATTAAA TTTATGGGAG AAAAACAAGA 4980
AAAGGCACGC CTATCAGCTG TTACGCGATC TGTAGCATCC CGTCAATTGG AGGCAAGTGG 5040
TAGTAATGGT TCCAACACTT CAACTAATGG AGCTCTTGGC GTCGCCGGAC GCGTCCAACT 5100
GGCACCCAAG TTGAGTGAAG ATGTTAAAGA AAAAATGGAA CAACAATTAA AATTACAGCG 5160
CGCTGTTCAT CAGCAGAGAA AATTGGTTGC AACTGGCGAA ATAACCCGTT CTGTGACACC 5220
AGTTAAAGGC CAAGTTATCG GTAGCAGGCG TGTCATTGTT AAAAACCCTG ATGGCACAAC 5280
TCGAATTATT CAGCAGGCAG TAACACAGGT TTCAAGAACA GGAGGAGCTA ATACTGCAGC 5340
AGCAGCTGCT TCACCTACTG TAGGAGGCTC GACAAGCACT CAATCAAATC CATCCACATC 5400
TACACCGCAT AAAGTACAAA TTATAAGGGG CCCAGATGGC AAAGTAAGCG TACGCGGGTT 5460
GAATCCTGGG CAGCAGCTGG TTCAAATGCC GGATGGAAAA CTCCATGTGC TGACTACCAC 5520
AACATCTTCA AATTCGGCGG GGCAAGGAAA CAAAATGAAG GTTCCCATTA AGCCAGCTTC 5580
TACTTCGTCG TCACCGGCAA TCAGTTCAGC ACAGACTACT ACAAATCCAG TGACGCCAGT 5640
GATAAAGCAA ATTGCAGTTA AACATGTCAC GAAAAATTCT GCGACCCAAT CCATAGCATC 5700
ATCCTCGCGC GTAGCCTTAC CGCTTGCTCA AATTAAGAAT AAGTTGTTAC TGGCCCAACA 5760
GCAGCAGCAA TCAACATCTT CATCACCAGC AACTTCATCA TCCCCTGTGC AAAAGATAGT 5820
GTCGAAAGTG GTTAACACTA GTACCTCTGG GCAAACTCTA CAGCAAGTAT TCGTACAGTC 5880
TGGGTCAAAA CTGGTAGTGG GCCAAAATGC ACAAGGGCAA AAGGTTATTA TATCTACATC 5940
GGCGGCACAA CAGCAAGGAA CATCACCGGT TCAACAGCAG CAACTAGTAC AATCGCAACC 6000
AATTCAGCAG TCACCACAAC AGATCTCCAT GACACAGGTC GGTAATCAAC CAACGCAAAA 6060
AGTAATTCAG CAAATTGTTA ATACCAGCAA CGTGCAGCAG CAGATAGTAG TTGGCGGTCA 6120
ACGGATTATC TTAAGCCCCG GTCAAACTAT TGTTACTCAG AGGAATGTGC CGCAGAGTCA 6180
AGCATTGCAG ATGGTTCAGC AGCAGATTCA AACCCAGCAG CAGCAGCAAC AACATCATGT 6240
CGTCCAGCCT CAGCAACAAT TCGTTGTTCA ATCAAACCAA ATTGTACAAT CTTCGCCAAG 6300
TGCACAAACC AAACTGGTTA AACAGCTTGT GGTTCAACAA CAATCGCAGC AAACCATTGA 6360
AGAAAAAACG CAAATCACCA CGACTGATAG CAATGAAACT GGCACACAAC AAGTCTTGGT 6420
TCCAAATTCA ACTTTAGCCC AGCAGTTAGC ACAGGGCAAA TTGCAGGTGG CAACAGTGAA 6480
TGGGCAACAA GTAATCGTAA AACCGTTGGG AAATAATCAG GCTCAAATCG TGGCACATAT 6540
TAAACACCAA GGTGATGGGA ACGCTCACAT CGTTACAAGT AATTCAGCTA CTGCAGTACC 6600
TCAAGCTAAC CCGCAGACCT CACCAGTCAA GCAACAGGCT CTCCCACCAC AAAGTCCACA 6660
ACAAGTCGTT GTGCAGCAGC AGCAAATACA TCAACAGTCA CCCACAAACT TCGAAAGTGG 6720
CGTTACCCCA ATAACTCAGC AGCCGGTTCT CACCCAGGCT GTCCAGGCTC CAGCCCAACA 6780
GCAAGCCTTG AGTGTTGAGG AAAGTCTTCT GCAGAATCAG CCGCCTGGAA CAGTAATTAA 6840
ATGTGTCACC GCTCAAGTAT TGCAAACCGA GCATGGTCCA CGTATAGTAT TGCAAGGCCT 6900
GGTGGGCAAC GATTTCACTG CACAACAACT GCAATTGGTG CAAACGCAGG TGAAGCAGCA 6960
ACTAATGAAG GCTCAAGAGT CAAATGGCAA ACTTGGTGTT CTAGGCCCAA CAAAAATATA 7020
CTTGGCGGTA CAGCCGGAAA ATGCAGTTCA ATCACAGCCA CCTCCTCTAA CCCCTGTTCA 7080
CCAATCGGCT GCGCATCAGC AAACCAACAA CATCGAAATC GACGCCGATA CGCTAGCAAC 7140
AACTTACGAA GCCAATTCAA CTATTAAAGA TATTGCTATT AATAATGGCG ATGATCAGGA 7200
AAACAGTAAA TGTGCAGAAA CAGAAAATTC TAATATTACA ACTAATGAGT CCTTTGCCGG 7260
TACATCTTCC CTATTAGAGG GTTCAGAACA TGATGAACCA ACTAACCTTG CCGGCCTCGA 7320
TATATCAGAA ACAGACTTAG AAAATAAACA AAACGAAAGC TTCGTTGTTA CCAGAGGATA 7380
CATACAGAAG TCTATTTCAA ATGCTCTGAA ACAAGGTAAT TTAAGTCCGG AACTTGAAGA 7440
AAAACTTGTT TGTATGCAGA AGCAACAAGA AAATGCGAAT TCGACGAATG AGTGGGAAAC 7500
ATGCTCAAGG GGCAGTGTGA ATGAGGAAGC ACTAACTCCC AGTCGCCAAA CTGATGACAC 7560
TGAATGGAAA ATTCGTACTT CCTTAAGACG CCCAAATGCT ATGACAACAA GCAGCCAATT 7620
TAATCGAATT TTAAAAAAAA ATCGGAGCAA GAATGACGAA GTCGCTGAAC TTGGAGAGCA 7680
AAAGCAATCG CAATTGGAAC GTCATAAAGA ATTGCTTAAA AAAAATATTT TGCGCAAGCG 7740
TTCCTTATTA GAGCGTAATT TACAAAGCGA AATACACGAA GATGTAAAAA CTAAAGTCCA 7800
AAGACATGTA CGCCCCTTAA GTAACGCTTC ACCGGATGAA CAAAGCGAAA ATGAGAGAAG 7860
TGGCGAACCA AATTTAGATT TTAAACGGAC AGAGGTGCAG AACCCCAGAC ATGGCGCAGG 7920
CCGACCAAAA AAGTTGACAA GAAAAAAGGA AAAGTTGTAT TGCATTTGCC GTACTCCATA 7980
TGATGACACA AAGTTTTACG TGGGGTGCGA CTTGTGCAGC AATTGGTTCC ATGGGGATTG 8040
TGTCAGTATT ACCGAGGAAG CTTCTAAAAA ACTATCGGAG TTCATTTGCA TTGATTGCAA 8100
GAGGGCGAGA GAAACGCAAC AGCTTTACTG TAGCTGTCGT CAACCATACG ACGAGTCACA 8160
ATTTTATATA TGCTGTGATA AATGCCAGGA TTGGTTTCAT GGCCGTTGCG TTGGAATACT 8220
TCAGAGCGAA GCAGAGTTTA TTGATGAATA TGTTTGCCCT GAATGCCAAC GCAAAAACGA 8280
TGCTAACGCT GCAAATATGA AGAAACTGAC TTCAAATGAC GTTGAAGAGC TGAAAAACTT 8340
AATTAAGCAG ATGCAGTTAC ACAAAAGTGC TTGGCCATTT ATGGAACCGG TTGATCCGAA 8400
GGAAGCACCC GATTATTACA AAGTGATTAA AGAGCCAATG GATCTCAAAC GGATGGAAAT 8460
TAAACTCGAA TCAAACACCT ATACCAAACT ATCTGAGTTT ATAGGCGATA TGACAAAAAT 8520
TTTTGACAAC TGCCGTTACT ATAACCCAAA AGAATCATCC TTTTATAAGT GTGCTGAAGC 8580
ACTAGAGTCA TACTTTGTGC AAAAAATTAA AAATTTTCGC GAAAATGTTT TTGACCAAAG 8640
AACATAAGAA ATAATAGCCC TTGAAAACTT TAGAACAAAT GATTATAGTT TATAAAGACA 8700
CTTCTAACAA TTTGAAAAAC GTCCTTCAGT TATGTATTCT TATTTTGAAT CAAATGTTAT 8760
ATAAACATAT ATTATCAATA AAAACACATA TAATTAATTA TAATAAATTA TGTACATATT 8820
GACCATATTT AGTAACGTAC ACCAGTATGC AATAAATTTC ATATTCACCA GACATTTGTA 8880
AGATTAAAAA TAATTAAGTA AAACCCCCTT TGTACAAAAC ATTAAAGTGT AAATAAACAG 8940
CATGCATTTC ATTTGATATC CTTATCATAT GCTGTAGGTT TAAACTTAGG CGTATGTAAC 9000
TTGTAAAAAT ACAAGCTTAT 9021
Sequence Source Ensembl
Keyword

KW-0025--Alternative splicing
KW-0103--Bromodomain
KW-0156--Chromatin regulator
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0217--Developmental protein
KW-0903--Direct protein sequencing
KW-0238--DNA-binding
KW-0479--Metal-binding
KW-0539--Nucleus
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0677--Repeat
KW-0804--Transcription
KW-0805--Transcription regulation
KW-0862--Zinc
KW-0863--Zinc-finger
--
Interpro

IPR001487--Bromodomain
IPR018359--Bromodomain_CS
IPR018501--DDT_dom
IPR028942--WHIM1_dom
IPR019786--Zinc_finger_PHD-type_CS
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD
PROSITE

PS00633--BROMODOMAIN_1
PS50014--BROMODOMAIN_2
PS50827--DDT
PS01359--ZF_PHD_1
PS50016--ZF_PHD_2
Pfam

PF00439--Bromodomain
PF02791--DDT
PF00628--PHD
PF15612--WHIM1
Gene Ontology

GO:0016589--C:NURF complex
GO:0003677--F:DNA binding
GO:0016922--F:ligand-dependent nuclear receptor binding
GO:0070577--F:lysine-acetylated histone binding
GO:0035064--F:methylated histone binding
GO:0008270--F:zinc ion binding
GO:0006325--P:chromatin organization
GO:0006338--P:chromatin remodeling
GO:0048813--P:dendrite morphogenesis
GO:0035076--P:ecdysone receptor-mediated signaling pathway
GO:0030097--P:hemopoiesis
GO:0046331--P:lateral inhibition
GO:0007095--P:mitotic G2 DNA damage checkpoint
GO:0045824--P:negative regulation of innate immune response
GO:0046426--P:negative regulation of JAK-STAT cascade
GO:0006334--P:nucleosome assembly
GO:0042766--P:nucleosome mobilization
GO:0045747--P:positive regulation of Notch signaling pathway
GO:0035073--P:pupariation
GO:0010468--P:regulation of gene expression
GO:0006357--P:regulation of transcription from RNA polymerase II promoter
GO:0019233--P:sensory perception of pain
GO:0048515--P:spermatid differentiation
GO:0006351--P:transcription, DNA-templated
Orthology
WERAM ID Ensembl Protein ID Species Identity E-value Score
WERAM-Pem-0098 ENSPMAP00000010155.1 Petromyzon marinus 53 8e-105 380
WERAM-Asm-0158 ENSAMXP00000015809.1 Astyanax mexicanus 50 1e-104 380
WERAM-Gaga-0038 ENSGALP00000005731.3 Gallus gallus 52 3e-104 379
WERAM-Meg-0081 ENSMGAP00000007705.2 Meleagris gallopavo 52 5e-104 378
WERAM-Orc-0156 ENSOCUP00000013650.2 Oryctolagus cuniculus 52 5e-104 378
WERAM-Anp-0050 ENSAPLP00000005439.1 Anas platyrhynchos 52 6e-104 378
WERAM-Eqc-0162 ENSECAP00000017752.1 Equus caballus 53 6e-104 378
WERAM-Otg-0081 ENSOGAP00000006293.2 Otolemur garnettii 52 8e-104 377
WERAM-Leo-0136 ENSLOCP00000016741.1 Lepisosteus oculatus 49 8e-104 377
WERAM-Mim-0113 ENSMICP00000010945.1 Microcebus murinus 53 1e-103 377
WERAM-Pof-0061 ENSPFOP00000005074.2 Poecilia formosa 49 1e-103 377
WERAM-Fia-0038 ENSFALP00000002451.1 Ficedula albicollis 52 1e-103 377
WERAM-Mod-0029 ENSMODP00000004239.3 Monodelphis domestica 53 2e-103 376
WERAM-Aim-0215 ENSAMEP00000019450.1 Ailuropoda melanoleuca 53 2e-103 376
WERAM-Caf-0128 ENSCAFP00000017006.3 Canis familiaris 53 2e-103 376
WERAM-Pat-0078 ENSPTRP00000016254.5 Pan troglodytes 52 2e-103 376
WERAM-Hos-0197 ENSP00000315454.4 Homo sapiens 52 2e-103 376
WERAM-Bot-0133 ENSBTAP00000019440.5 Bos taurus 52 2e-103 376
WERAM-Loa-0163 ENSLAFP00000014732.3 Loxodonta africana 52 3e-103 375
WERAM-Ect-0089 ENSETEP00000010402.1 Echinops telfairi 53 3e-103 375
WERAM-Xim-0095 ENSXMAP00000008377.1 Xiphophorus maculatus 53 3e-103 375
WERAM-Fec-0023 ENSFCAP00000001788.3 Felis catus 53 3e-103 375
WERAM-Myl-0026 ENSMLUP00000002097.2 Myotis lucifugus 53 3e-103 375
WERAM-Nol-0016 ENSNLEP00000002048.2 Nomascus leucogenys 52 3e-103 375
WERAM-Sah-0101 ENSSHAP00000011224.1 Sarcophilus harrisii 53 3e-103 375
WERAM-Ova-0166 ENSOARP00000016736.1 Ovis aries 52 3e-103 375
WERAM-Ptv-0100 ENSPVAP00000009157.1 Pteropus vampyrus 52 3e-103 375
WERAM-Tag-0060 ENSTGUP00000004640.1 Taeniopygia guttata 52 3e-103 375
WERAM-Poa-0073 ENSPPYP00000009623.2 Pongo abelii 52 3e-103 375
WERAM-Mup-0169 ENSMPUP00000014579.1 Mustela putorius furo 52 4e-103 375
WERAM-Chh-0090 ENSCHOP00000010104.1 Choloepus hoffmanni 53 4e-103 375
WERAM-Tut-0158 ENSTTRP00000013247.1 Tursiops truncatus 52 4e-103 375
WERAM-Chs-0047 ENSCSAP00000000546.1 Chlorocebus sabaeus 52 1e-102 374
WERAM-Ten-0173 ENSTNIP00000017134.1 Tetraodon nigroviridis 53 1e-102 373
WERAM-Orla-0163 ENSORLP00000019077.1 Oryzias latipes 49 2e-102 373
WERAM-Tas-0063 ENSTSYP00000005786.1 Tarsius syrichta 53 3e-102 372
WERAM-Dar-0178 ENSDARP00000102656.3 Danio rerio 51 4e-102 372
WERAM-Soa-0025 ENSSARP00000002698.1 Sorex araneus 52 4e-102 372
WERAM-Orn-0075 ENSONIP00000008143.1 Oreochromis niloticus 50 1e-101 370
WERAM-Pes-0076 ENSPSIP00000009390.1 Pelodiscus sinensis 52 2e-101 369
WERAM-Mam-0079 ENSMMUP00000012736.2 Macaca mulatta 65 6e-101 368
WERAM-Gaa-0069 ENSGACP00000009172.1 Gasterosteus aculeatus 51 1e-100 367
WERAM-Ere-0104 ENSEEUP00000011448.1 Erinaceus europaeus 51 2e-100 366
WERAM-Dan-0190 ENSDNOP00000020775.1 Dasypus novemcinctus 53 2e-100 366
WERAM-Xet-0009 ENSXETP00000003362.3 Xenopus tropicalis 51 3e-100 365
WERAM-Lac-0134 ENSLACP00000015688.1 Latimeria chalumnae 52 4e-100 365
WERAM-Ora-0077 ENSOANP00000012800.2 Ornithorhynchus anatinus 64 5e-100 365
WERAM-Mum-0168 ENSMUSP00000052303.8 Mus musculus 50 5e-100 364
WERAM-Gam-0199 ENSGMOP00000019051.1 Gadus morhua 52 3e-99 362
WERAM-Tar-0021 ENSTRUP00000004515.1 Takifugu rubripes 52 5e-99 361
WERAM-Ran-0202 ENSRNOP00000063388.1 Rattus norvegicus 65 1e-94 347
WERAM-Caj-0239 ENSCJAP00000016250.1 Callithrix jacchus 65 7e-94 344
WERAM-Tub-0127 ENSTBEP00000013883.1 Tupaia belangeri 57 2e-93 343
WERAM-Prc-0068 ENSPCAP00000006510.1 Procavia capensis 52 4e-72 272
WERAM-Gog-0121 ENSGGOP00000010106.2 Gorilla gorilla 61 3e-71 269
WERAM-Cap-0047 ENSCPOP00000003843.2 Cavia porcellus 61 2e-70 266
WERAM-Anc-0004 ENSACAP00000000277.2 Anolis carolinensis 61 2e-70 266
WERAM-Ict-0119 ENSSTOP00000011981.2 Ictidomys tridecemlineatus 61 3e-70 266
WERAM-Vip-0018 ENSVPAP00000001709.1 Vicugna pacos 61 4e-70 265
WERAM-Dio-0097 ENSDORP00000009714.1 Dipodomys ordii 61 5e-70 265
WERAM-Mae-0098 ENSMEUP00000009407.1 Macropus eugenii 61 8e-70 264
WERAM-Cii-0050 ENSCINP00000019842.3 Ciona intestinalis 39 3e-63 243
WERAM-Paa-0145 ENSPANP00000016514.1 Papio anubis 62 6e-58 225
WERAM-Cis-0085 ENSCSAVP00000019686.1 Ciona savignyi 48 1e-55 218
WERAM-Cae-0039 F26H11.2a Caenorhabditis elegans 34 7e-51 201
WERAM-Ocp-0004 ENSOPRP00000000497.1 Ochotona princeps 40 1e-37 157
WERAM-Sac-0018 YGR252W Saccharomyces cerevisiae 51 4e-25 116
WERAM-Met-0105 AES89502 Medicago truncatula 27 5e-24 112
WERAM-Asg-0022 AAS52978 Ashbya gossypii 50 9e-24 111
WERAM-Sus-0168 ENSSSCP00000026852.1 Sus scrofa 51 1e-23 111
WERAM-Kll-0002 CAH02813 Kluyveromyces lactis 49 1e-23 111
WERAM-Cag-0011 CAG59253 Candida glabrata 49 2e-23 110
WERAM-Scj-0018 EEB07672 Schizosaccharomyces japonicus 50 9e-23 108
WERAM-Scp-0009 SPAC1952.05.1:pep Schizosaccharomyces pombe 49 2e-22 107
WERAM-Glm-0138 GLYMA12G02470.1 Glycine max 27 4e-22 105
WERAM-Brr-0074 Bra014803.1-P Brassica rapa 46 1e-21 105
WERAM-Bro-0075 Bo4g119820.1 Brassica oleracea 46 1e-21 104
WERAM-Arl-0085 fgenesh2_kg.5__ 1855__ AT3G54610.1 Arabidopsis lyrata 43 2e-21 103
WERAM-Viv-0049 VIT_07s0141g00140.t01 Vitis vinifera 45 2e-21 103
WERAM-Art-0090 AT3G54610.1 Arabidopsis thaliana 45 2e-21 103
WERAM-Kop-0030 CAY71195 Komagataella pastoris 50 3e-21 103
WERAM-Put-0007 PTTG_04942P0 Puccinia triticina 37 3e-21 103
WERAM-Ors-0097 OS10T0415900-01 Oryza sativa 46 4e-21 102
WERAM-Org-0101 ORGLA10G0086200.1 Oryza glaberrima 46 4e-21 102
WERAM-Yal-0013 CAG79052 Yarrowia lipolytica 46 6e-21 102
WERAM-Coi-0002 EAS35235 Coccidioides immitis 49 1e-20 101
WERAM-Thc-0013 EOX94594 Theobroma cacao 42 1e-20 101
WERAM-Nec-0005 EFNCRP00000000528 Neurospora crassa 49 1e-20 100
WERAM-Pug-0010 EFP80056 Puccinia graminis 45 1e-20 100
WERAM-Sei-0131 Si035227m Setaria italica 46 2e-20 100
WERAM-Ast-0038 CADATEAP00010086 Aspergillus terreus 48 2e-20 100
WERAM-Asf-0031 CADAFLAP00011133 Aspergillus flavus 48 2e-20 100
WERAM-Asni-0002 CADANGAP00000792 Aspergillus niger 48 2e-20 100
WERAM-Aso-0018 CADAORAP00003726 Aspergillus oryzae 48 2e-20 100
WERAM-Orr-0111 ORUFI10G10500.1 Oryza rufipogon 47 3e-20 99.8
WERAM-Orm-0097 OMERI10G07340.1 Oryza meridionalis 47 3e-20 99.8
WERAM-Asfu-0034 CADAFUAP00007746 Aspergillus fumigatus 48 3e-20 99.8
WERAM-Miv-0025 MVLG_03550T0 Microbotryum violaceum 48 3e-20 99.8
WERAM-Mua-0115 GSMUA_Achr8P04400_001 Musa acuminata 45 3e-20 99.8
WERAM-Asc-0021 CADACLAP00004797 Aspergillus clavatus 48 3e-20 99.8
WERAM-Orp-0101 OPUNC10G08630.1 Oryza punctata 44 4e-20 99.8
WERAM-Spr-0018 CBQ72364 Sporisorium reilianum 47 4e-20 99.8
WERAM-Orgl-0105 OGLUM10G09860.1 Oryza glumaepatula 47 4e-20 99.4
WERAM-Chg-0013 EAQ90930 Chaetomium globosum 46 4e-20 99.4
WERAM-Prp-0053 EMJ02916 Prunus persica 44 6e-20 99.0
WERAM-Sob-0007 Sb01g021950.1 Sorghum bicolor 43 7e-20 99.0
WERAM-Fuo-0036 FOXG_14847P0 Fusarium oxysporum 44 8e-20 98.6
WERAM-Php-0126 PP1S84_88V6.1 Physcomitrella patens 44 1e-19 98.2
WERAM-Pot-0023 POPTR_0002s04670.1 Populus trichocarpa 42 1e-19 97.8
WERAM-Mao-0010 MGG_03677T0 Magnaporthe oryzae 48 2e-19 97.4
WERAM-Trr-0032 EGR47291 Trichoderma reesei 47 3e-19 97.1
WERAM-Orni-0107 ONIVA10G09370.1 Oryza nivara 42 3e-19 97.1
WERAM-Sem-0025 EFJ38417 Selaginella moellendorffii 43 3e-19 96.7
WERAM-Orl-0072 KN539534.1_FGP007 Oryza longistaminata 47 3e-19 96.7
WERAM-Tra-0023 Traes_1BS_D81E948D7.1 Triticum aestivum 42 3e-19 96.7
Created Date 25-Jun-2016