| Tag |
Content |
| WERAM ID |
WERAM-Scp-0001 |
| Ensembl Protein ID |
SPAC1002.05c.1:pep |
| Uniprot Accession |
Q9US53; JMJ2_SCHPO
|
| Genbank Protein ID |
NP_593492.1
|
| Protein Name |
Jumonji/ARID domain-containing protein 2 |
| Genbank Nucleotide ID |
NM_001018926.2
|
| Gene Name |
JMJ2 |
| Ensembl Information |
|
| Details |
| Type |
Family |
Domain |
Substrates |
AA |
References (PMIDs) |
| HDM |
JmjC_only |
Jmjc |
H3K4me3 |
K |
17550896
|
|
| Status |
Reviewed |
| Classification |
| Type |
Family |
E-value |
Score |
Start |
End |
| HDM |
JmjC_only |
4.70e-38 |
128.2 |
356 |
588 |
|
| Organism |
Schizosaccharomyces pombe |
| NCBI Taxa ID |
284812 |
Functional Description
(View) |
|
| Domain Profile |
HDM JmjC_only
JmjC_only.txt 83 qvkqedllltkftliaprplletvlep 109
++ +++++++ f++++++++ e ++e+
SPAC1002.05c.1:pep 356 EKYCDNFKKNYFSKFKDSEITEDIVEK 382
56799*****************99985 PP
JmjC_only.txt 10 tfsdqlwqlkeelsepfyclvgsn.........wfltGpassgfplHvddi..eaflvqveGrkr.wrlyepsepaellk.....lasdeq 83
++s+++w+l++++s++ ++l++++ w+++G+++s+f++Hv+d+ +++++q++G+++ w+++ p ++ae+++ +a+d +
SPAC1002.05c.1:pep 422 PYSKDTWNLNVIASTNGSLLSYIDnpvsgitcpWLYVGMCFSTFCWHVEDNytYSVNYQHYGDTKlWYGI-PGDQAERFEraaldIAPDLV 511
89*************************************************************999****.******************** PP
JmjC_only.txt 84 vkqedllltkftliaprplletvle.......pgellyiprgtwHqa......lsldvtlsvsqnfssetflenvvlk 148
+kq+dll++ +t+i+p++l++++++ p+e+++++++++H++ ++++v++ +++++ +++f++n vlk
SPAC1002.05c.1:pep 512 KKQKDLLYQLATMINPDELQKRGVDvyfidqgPNEFVITFPKSFHAGinhgfnINEAVNF-APKDWLLNGFSLNGVLK 588
***************************************************999******.9***********99876 PP
|
Protein Sequence
(Fasta) | MSKSTFHQTS PSFVQYTHAT DKLKPAPHGM NTRGNNLSSM SKNTGQRKQR SKSIHGLPVA 60
PVFYPDKEEF QDSIGYINKI APIGEKYGII KIVPPAGWNP PMQLDMNKFS FRTRRQDLHM 120
MDLRFREIVS YDERVYRFFC NLGMELPESF FISNTSIDLY SLMRCIDSHA SLSEKELKVH 180
VWKRILRELS IPFTNASLKE ASDLYLRYIF PFEDFVRKYQ TSEDQCFETD LFPKFFTKDE 240
HSNISIKDQK TSKQFNPETN ESVGILQNQE SKRNEQIKQQ YMPADNFGSN DNHSHNKKRR 300
LSSLSTNNNH LCDNCHKPVN CEVEDTCKEA YCTKCIINPY EFGFETGNYY TLSNFEKYCD 360
NFKKNYFSKF KDSEITEDIV EKEYWKLVKD NNTSLEVEYG ADLSTLDQGS AFPSLAKNPV 420
NPYSKDTWNL NVIASTNGSL LSYIDNPVSG ITCPWLYVGM CFSTFCWHVE DNYTYSVNYQ 480
HYGDTKLWYG IPGDQAERFE RAALDIAPDL VKKQKDLLYQ LATMINPDEL QKRGVDVYFI 540
DQGPNEFVIT FPKSFHAGIN HGFNINEAVN FAPKDWLLNG FSLNGVLKYQ SLLKPPVLSH 600
DMLVYNLATN PASEISVSEL RPWVHEAVKR ELGIRIMIRG RYDLKEILYR ELMEDAENWQ 660
CQHCKAFSYF SQVACSCKSI TVCPLHIEYL CKCDLSNKTL RLKVDDNELQ KLLSY 715Protein Fasta Sequence
>SPAC1002.05c.1:pep|JMJ2|Schizosaccharomyces pombe
MSKSTFHQTSPSFVQYTHATDKLKPAPHGMNTRGNNLSSMSKNTGQRKQRSKSIHGLPVAPVFYPDKEEFQDSIGYINKIAPIGEKYGIIKIVPPAGWNPPMQLDMNKFSFRTRRQDLHMMDLRFREIVSYDERVYRFFCNLGMELPESFFISNTSIDLYSLMRCIDSHASLSEKELKVHVWKRILRELSIPFTNASLKEASDLYLRYIFPFEDFVRKYQTSEDQCFETDLFPKFFTKDEHSNISIKDQKTSKQFNPETNESVGILQNQESKRNEQIKQQYMPADNFGSNDNHSHNKKRRLSSLSTNNNHLCDNCHKPVNCEVEDTCKEAYCTKCIINPYEFGFETGNYYTLSNFEKYCDNFKKNYFSKFKDSEITEDIVEKEYWKLVKDNNTSLEVEYGADLSTLDQGSAFPSLAKNPVNPYSKDTWNLNVIASTNGSLLSYIDNPVSGITCPWLYVGMCFSTFCWHVEDNYTYSVNYQHYGDTKLWYGIPGDQAERFERAALDIAPDLVKKQKDLLYQLATMINPDELQKRGVDVYFIDQGPNEFVITFPKSFHAGINHGFNINEAVNFAPKDWLLNGFSLNGVLKYQSLLKPPVLSHDMLVYNLATNPASEISVSELRPWVHEAVKRELGIRIMIRGRYDLKEILYRELMEDAENWQCQHCKAFSYFSQVACSCKSITVCPLHIEYLCKCDLSNKTLRLKVDDNELQKLLSY |
Nucleotide Sequence
(Fasta) | ATGAGCAAGT CTACTTTTCA TCAAACTTCC CCATCTTTTG TACAATACAC TCATGCTACA 60
GATAAACTAA AACCTGCACC TCATGGGATG AATACGCGGG GAAATAACTT ATCCTCTATG 120
TCAAAAAATA CCGGACAAAG AAAACAGCGT TCCAAATCCA TTCATGGACT TCCAGTTGCT 180
CCCGTTTTTT ATCCTGATAA AGAGGAATTT CAGGACTCTA TCGGTTATAT TAATAAGATA 240
GCTCCAATCG GTGAAAAATA TGGTATCATA AAAATCGTTC CTCCTGCTGG TTGGAATCCA 300
CCGATGCAAC TTGACATGAA CAAGTTTTCC TTCCGTACTC GGCGGCAGGA TTTGCATATG 360
ATGGATCTTC GATTTCGTGA AATAGTCTCT TACGATGAAC GCGTTTACCG TTTTTTTTGC 420
AATCTGGGCA TGGAGCTCCC GGAATCATTT TTTATTTCCA ATACGTCTAT CGACTTATAC 480
AGCTTAATGC GTTGTATTGA TTCTCATGCA TCTCTAAGTG AGAAGGAATT AAAAGTTCAT 540
GTATGGAAAA GGATTTTACG AGAACTTTCA ATTCCTTTTA CTAATGCATC ATTAAAGGAA 600
GCAAGTGACT TGTATTTAAG GTATATTTTT CCATTTGAGG ATTTCGTCAG AAAATATCAG 660
ACCTCTGAGG ATCAATGCTT TGAAACTGAT CTCTTCCCTA AATTTTTTAC AAAAGACGAA 720
CATTCTAATA TTAGTATTAA AGATCAGAAG ACATCTAAAC AATTTAACCC CGAAACTAAT 780
GAGTCCGTAG GAATTCTTCA AAACCAAGAA TCCAAGAGAA ATGAGCAGAT TAAACAACAA 840
TATATGCCAG CCGATAATTT TGGATCAAAT GATAATCACT CACATAATAA AAAGCGACGA 900
TTGAGCTCTC TGTCAACGAA TAACAACCAC TTATGTGACA ATTGTCACAA ACCTGTCAAT 960
TGTGAAGTCG AAGATACGTG TAAAGAAGCG TATTGTACTA AATGTATAAT TAATCCATAT 1020
GAGTTTGGGT TTGAAACAGG GAATTATTAT ACTTTATCGA ACTTTGAAAA ATACTGTGAC 1080
AATTTTAAGA AAAATTATTT TTCTAAATTT AAAGACTCGG AGATAACTGA GGATATTGTT 1140
GAAAAAGAGT ATTGGAAACT CGTAAAAGAC AATAATACAA GCCTTGAAGT GGAATACGGT 1200
GCAGATTTAT CAACCCTTGA TCAGGGCAGC GCCTTCCCTA GTTTAGCCAA AAATCCAGTG 1260
AATCCTTACT CTAAGGACAC ATGGAATTTA AATGTTATAG CATCCACAAA TGGTTCTCTA 1320
TTAAGCTATA TAGATAATCC TGTTTCAGGT ATAACCTGTC CGTGGCTGTA CGTTGGAATG 1380
TGTTTTTCAA CTTTTTGTTG GCATGTCGAG GATAACTATA CTTATTCCGT AAATTATCAA 1440
CATTATGGAG ACACAAAATT ATGGTATGGA ATTCCAGGTG ATCAAGCCGA GAGGTTTGAA 1500
CGCGCCGCTC TTGATATTGC TCCTGATTTG GTAAAAAAAC AAAAAGATCT GCTTTACCAA 1560
TTAGCTACAA TGATCAACCC TGATGAGCTA CAAAAAAGAG GTGTCGATGT TTATTTCATC 1620
GACCAGGGGC CTAATGAATT CGTGATTACC TTTCCAAAAA GCTTTCACGC AGGAATTAAT 1680
CATGGGTTTA ACATTAATGA GGCAGTGAAT TTTGCTCCCA AAGATTGGTT ACTAAACGGA 1740
TTCTCTTTGA ATGGCGTTTT GAAATATCAG TCACTTCTTA AACCTCCTGT ACTTTCACAT 1800
GATATGTTGG TTTACAATTT AGCGACAAAT CCGGCGTCAG AGATAAGTGT GTCTGAGCTA 1860
AGGCCTTGGG TGCATGAGGC TGTCAAACGT GAATTAGGTA TACGTATCAT GATACGAGGA 1920
CGCTATGATT TAAAGGAAAT ACTTTATCGT GAATTAATGG AGGATGCCGA AAATTGGCAA 1980
TGCCAGCATT GCAAAGCATT TTCATACTTC TCTCAAGTTG CTTGTTCTTG CAAGTCGATT 2040
ACTGTATGTC CATTACACAT CGAATATCTT TGCAAGTGCG ATTTAAGCAA TAAGACCTTA 2100
CGCCTAAAAG TCGACGATAA TGAGTTACAG AAGTTGCTAA GTTATTAAAG TTACATTTAT 2160
TCTTTTCTAA AACAATTATT TTGCAATTTA TAAACCTATA TTTTCAAGGT CATTTACAAA 2220
CATCGTTGGA TTCATGTAAT GTAAACAATT
2251Nucleotide Fasta Sequence
>SPAC1002.05c.1:pep|JmjC_only|Schizosaccharomyces pombe
ATGAGCAAGTCTACTTTTCATCAAACTTCCCCATCTTTTGTACAATACACTCATGCTACAGATAAACTAAAACCTGCACCTCATGGGATGAATACGCGGGGAAATAACTTATCCTCTATGTCAAAAAATACCGGACAAAGAAAACAGCGTTCCAAATCCATTCATGGACTTCCAGTTGCTCCCGTTTTTTATCCTGATAAAGAGGAATTTCAGGACTCTATCGGTTATATTAATAAGATAGCTCCAATCGGTGAAAAATATGGTATCATAAAAATCGTTCCTCCTGCTGGTTGGAATCCACCGATGCAACTTGACATGAACAAGTTTTCCTTCCGTACTCGGCGGCAGGATTTGCATATGATGGATCTTCGATTTCGTGAAATAGTCTCTTACGATGAACGCGTTTACCGTTTTTTTTGCAATCTGGGCATGGAGCTCCCGGAATCATTTTTTATTTCCAATACGTCTATCGACTTATACAGCTTAATGCGTTGTATTGATTCTCATGCATCTCTAAGTGAGAAGGAATTAAAAGTTCATGTATGGAAAAGGATTTTACGAGAACTTTCAATTCCTTTTACTAATGCATCATTAAAGGAAGCAAGTGACTTGTATTTAAGGTATATTTTTCCATTTGAGGATTTCGTCAGAAAATATCAGACCTCTGAGGATCAATGCTTTGAAACTGATCTCTTCCCTAAATTTTTTACAAAAGACGAACATTCTAATATTAGTATTAAAGATCAGAAGACATCTAAACAATTTAACCCCGAAACTAATGAGTCCGTAGGAATTCTTCAAAACCAAGAATCCAAGAGAAATGAGCAGATTAAACAACAATATATGCCAGCCGATAATTTTGGATCAAATGATAATCACTCACATAATAAAAAGCGACGATTGAGCTCTCTGTCAACGAATAACAACCACTTATGTGACAATTGTCACAAACCTGTCAATTGTGAAGTCGAAGATACGTGTAAAGAAGCGTATTGTACTAAATGTATAATTAATCCATATGAGTTTGGGTTTGAAACAGGGAATTATTATACTTTATCGAACTTTGAAAAATACTGTGACAATTTTAAGAAAAATTATTTTTCTAAATTTAAAGACTCGGAGATAACTGAGGATATTGTTGAAAAAGAGTATTGGAAACTCGTAAAAGACAATAATACAAGCCTTGAAGTGGAATACGGTGCAGATTTATCAACCCTTGATCAGGGCAGCGCCTTCCCTAGTTTAGCCAAAAATCCAGTGAATCCTTACTCTAAGGACACATGGAATTTAAATGTTATAGCATCCACAAATGGTTCTCTATTAAGCTATATAGATAATCCTGTTTCAGGTATAACCTGTCCGTGGCTGTACGTTGGAATGTGTTTTTCAACTTTTTGTTGGCATGTCGAGGATAACTATACTTATTCCGTAAATTATCAACATTATGGAGACACAAAATTATGGTATGGAATTCCAGGTGATCAAGCCGAGAGGTTTGAACGCGCCGCTCTTGATATTGCTCCTGATTTGGTAAAAAAACAAAAAGATCTGCTTTACCAATTAGCTACAATGATCAACCCTGATGAGCTACAAAAAAGAGGTGTCGATGTTTATTTCATCGACCAGGGGCCTAATGAATTCGTGATTACCTTTCCAAAAAGCTTTCACGCAGGAATTAATCATGGGTTTAACATTAATGAGGCAGTGAATTTTGCTCCCAAAGATTGGTTACTAAACGGATTCTCTTTGAATGGCGTTTTGAAATATCAGTCACTTCTTAAACCTCCTGTACTTTCACATGATATGTTGGTTTACAATTTAGCGACAAATCCGGCGTCAGAGATAAGTGTGTCTGAGCTAAGGCCTTGGGTGCATGAGGCTGTCAAACGTGAATTAGGTATACGTATCATGATACGAGGACGCTATGATTTAAAGGAAATACTTTATCGTGAATTAATGGAGGATGCCGAAAATTGGCAATGCCAGCATTGCAAAGCATTTTCATACTTCTCTCAAGTTGCTTGTTCTTGCAAGTCGATTACTGTATGTCCATTACACATCGAATATCTTTGCAAGTGCGATTTAAGCAATAAGACCTTACGCCTAAAAGTCGACGATAATGAGTTACAGAAGTTGCTAAGTTATTAAAGTTACATTTATTCTTTTCTAAAACAATTATTTTGCAATTTATAAACCTATATTTTCAAGGTCATTTACAAACATCGTTGGATTCATGTAATGTAAACAATT
|
| Sequence Source |
Ensembl |
| Keyword |
KW-0181--Complete proteome
KW-0408--Iron
KW-0479--Metal-binding
KW-1185--Reference proteome
--
|
| Interpro |
IPR001606--ARID_dom
IPR003347--JmjC_dom
IPR003349--JmjN
IPR004198--Znf_C5HC2
|
| PROSITE |
PS51011--ARID
PS51184--JMJC
PS51183--JMJN
|
| Pfam |
PF02373--JmjC
PF02375--JmjN
PF02928--zf-C5HC2
|
| Gene Ontology |
GO:0000790--C:nuclear chromatin
GO:0005634--C:nucleus
GO:0003677--F:DNA binding
GO:0034648--F:histone demethylase activity (H3-dimethyl-K4 specific)
GO:0051864--F:histone demethylase activity (H3-K36 specific)
GO:0032453--F:histone demethylase activity (H3-K4 specific)
GO:0034647--F:histone demethylase activity (H3-trimethyl-K4 specific)
GO:0008270--F:zinc ion binding
GO:0006338--P:chromatin remodeling
GO:0016577--P:histone demethylation
GO:0070544--P:histone H3-K36 demethylation
GO:0034720--P:histone H3-K4 demethylation
GO:0034721--P:histone H3-K4 demethylation, trimethyl-H3-K4-specific
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
|
| Orthology |
|
| Created Date |
25-Jun-2016 |
