WERAM Information

Tag Content
WERAM ID WERAM-Art-0099
Ensembl Protein ID AT4G13460.2
Uniprot Accession Q9T0G7; SUVH9_ARATH
Genbank Protein ID NP_001031625.1; NP_193082.1
Protein Name Histone-lysine N-methyltransferase family member SUVH9
Genbank Nucleotide ID NM_001036548.1; NM_117420.2
Gene Name SUVH9;SDG22
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
AT4G13460 AT4G13460.2 AT4G13460.2
AT4G13460 AT4G13460.1 AT4G13460.1
Details
Type Family Domain Substrates AA References (PMIDs)
HMT SUV39 SET H3K9 K 20703330; 15659850
Status Reviewed
Classification
Type Family E-value Score Start End
HMT SUV39 4.10e-35 121.8 494 637
Organism Arabidopsis thaliana
NCBI Taxa ID 3702
Functional Description
(View)		 Histone methyltransferase family member that plays a role in gene silencing. According to PubMed:19043555, the protein does not bind S-adenosyl-L-methionine and lacks methyltransferase activity. Instead, it may function downstream of DRM2 in RNA-directed DNA methylation, binding to methylated DNA and recruiting DNA-directed RNA polymerase V to chromatin (PubMed:24463519).
Domain Profile
  HMT SUV39
    SUV39.txt   2 rLqvfktenkGwGvrclddiakgsFvciyaGeiltddeaekegleegdeyladldskesvenlkegyesdvplssdssntrqekdkeeseyiidakke 99 
                  rL+vf++ ++GwGvr+ld +++g+F+c+yaG  lt+++a+   +++gd+ ++  + +++ ++   +  +       + ++ ++ d    ++ +d +k+
  AT4G13460.2 494 RLEVFRSLETGWGVRSLDVLHAGAFICEYAGVALTREQANIL-TMNGDTLVYPARFSSARWEDWGDLSQ----VLADFERPSYPDIPPVDFAMDVSKM 586
                  8***************************************98.78888888888777666444333333....334568899**************** PP
    SUV39.txt 100 gnvgrflnHscspNlfvqnvfvdthdlrfprvafFaskrikagtELtwdYg 150
                   nv+++++Hs++pN++vq v++d+++l+fprv++Fa+++i+++tEL+ dYg
  AT4G13460.2 587 RNVACYISHSTDPNVIVQFVLHDHNSLMFPRVMLFAAENIPPMTELSLDYG 637
                  **************************************************6 PP
Protein Sequence
(Fasta)		MGSSHIPLDP SLNPSPSLIP KLEPVTESTQ NLAFQLPNTN PQALISSAVS DFNEATDFSS 60
DYNTVAESAR SAFAQRLQRH DDVAVLDSLT GAIVPVEENP EPEPNPYSTS DSSPSVATQR 120
PRPQPRSSEL VRITDVGPES ERQFREHVRK TRMIYDSLRM FLMMEEAKRN GVGGRRARAD 180
GKAGKAGSMM RDCMLWMNRD KRIVGSIPGV QVGDIFFFRF ELCVMGLHGH PQSGIDFLTG 240
SLSSNGEPIA TSVIVSGGYE DDDDQGDVIM YTGQGGQDRL GRQAEHQRLE GGNLAMERSM 300
YYGIEVRVIR GLKYENEVSS RVYVYDGLFR IVDSWFDVGK SGFGVFKYRL ERIEGQAEMG 360
SSVLKFARTL KTNPLSVRPR GYINFDISNG KENVPVYLFN DIDSDQEPLY YEYLAQTSFP 420
PGLFVQQSGN ASGCDCVNGC GSGCLCEAKN SGEIAYDYNG TLIRQKPLIH ECGSACQCPP 480
SCRNRVTQKG LRNRLEVFRS LETGWGVRSL DVLHAGAFIC EYAGVALTRE QANILTMNGD 540
TLVYPARFSS ARWEDWGDLS QVLADFERPS YPDIPPVDFA MDVSKMRNVA CYISHSTDPN 600
VIVQFVLHDH NSLMFPRVML FAAENIPPMT ELSLDYGVVD DWNAKLAICN
Nucleotide Sequence
(Fasta)		CTACAAACCA AAATAAACGG GTGTGGTGTG TTTGGTCTGG CCTTATACAC CAAATCAAAC 60
ACACCACCAT TTTTACCCAG AAATTTGAGT ACCAAGAGAG CTCTTTTTCA TCCTAAAGAG 120
ATCTTCAAAT TTAGATTTCA ACACATAAAA GGTATGAAAT TTTTCATTTT TTTTCCGGCT 180
ATTTTTTTTT GGAATAATCG TATCATAATT TCTCAATATC ACAACTTTAT ATTAAAAGCA 240
AATCTAAAGA AAAAACACAT TAGATTCTGT AGGAAAATAT TTGTGTAAGA GCTTCTTCTC 300
CGCCATGGAT TTAGCTTGAA AGGTGTTCTC CAAACAAAAC CCATTTCTTC GATTTCTCTG 360
ATAAACTCGT CAAACCCATT TCGCTTCTCG TTGCAAAAAA TGGGTTCTTC TCACATTCCT 420
CTTGATCCGT CTCTAAATCC GTCACCTTCA CTGATCCCAA AGCTTGAACC AGTCACTGAA 480
TCAACCCAAA ACTTGGCCTT TCAACTTCCA AACACAAACC CACAAGCCCT AATTTCATCA 540
GCCGTCTCCG ATTTCAACGA AGCCACAGAC TTTTCCTCAG ATTACAACAC CGTCGCCGAG 600
TCAGCCCGGT CTGCTTTCGC TCAACGGCTT CAACGTCACG ATGATGTTGC GGTTCTTGAT 660
TCCTTAACCG GAGCAATCGT ACCGGTTGAG GAGAATCCGG AACCGGAACC GAATCCTTAC 720
TCAACCAGTG ACTCTTCACC GTCGGTTGCT ACTCAACGAC CTAGACCGCA GCCACGTTCG 780
TCGGAGCTAG TGAGGATCAC TGATGTTGGA CCTGAAAGTG AGAGACAGTT TCGTGAACAT 840
GTGAGGAAGA CGAGAATGAT TTATGATTCT CTTAGGATGT TTTTGATGAT GGAAGAAGCT 900
AAACGTAATG GGGTTGGTGG AAGAAGAGCT AGAGCTGATG GTAAAGCTGG TAAAGCTGGT 960
TCAATGATGA GAGATTGTAT GTTGTGGATG AATCGTGATA AACGAATCGT CGGTTCGATT 1020
CCCGGTGTTC AAGTTGGGGA TATCTTCTTC TTTAGGTTTG AGTTATGTGT CATGGGCTTA 1080
CATGGACACC CTCAATCTGG GATCGATTTT CTTACAGGGA GTCTTAGTTC TAATGGGGAG 1140
CCAATAGCTA CTAGTGTGAT TGTTTCTGGT GGGTATGAGG ATGATGATGA TCAAGGAGAT 1200
GTGATTATGT ATACAGGTCA GGGTGGACAA GATAGGCTTG GAAGGCAAGC TGAACATCAG 1260
AGGCTGGAAG GTGGAAACCT TGCGATGGAA CGGAGTATGT ATTATGGGAT TGAAGTGAGA 1320
GTTATTAGAG GGTTGAAGTA TGAGAATGAG GTTTCTAGTA GAGTTTATGT TTATGATGGG 1380
TTGTTTAGGA TTGTTGATTC TTGGTTTGAT GTTGGGAAGT CTGGTTTCGG TGTGTTTAAA 1440
TATCGGTTGG AGAGGATTGA AGGACAGGCT GAGATGGGTA GTTCGGTGTT GAAGTTTGCT 1500
AGGACTCTTA AGACTAATCC ATTGTCTGTG AGACCGAGAG GTTACATCAA TTTCGATATC 1560
TCGAATGGGA AGGAGAATGT TCCTGTCTAT TTGTTTAACG ACATTGACAG CGATCAAGAA 1620
CCTTTGTATT ATGAGTATCT TGCGCAAACT TCGTTTCCTC CTGGCTTATT TGTTCAGCAA 1680
AGTGGTAATG CAAGTGGATG TGACTGTGTC AATGGTTGTG GCAGTGGCTG CCTTTGTGAA 1740
GCCAAGAATT CAGGTGAGAT TGCTTATGAT TATAATGGGA CGCTAATAAG ACAGAAACCG 1800
TTGATACATG AATGTGGATC AGCGTGTCAG TGCCCTCCAA GCTGTCGAAA CCGTGTGACT 1860
CAAAAGGGTT TGAGGAATAG GCTAGAAGTG TTTAGGTCAC TGGAAACGGG TTGGGGAGTT 1920
CGGTCTTTGG ATGTATTACA TGCTGGTGCT TTTATTTGTG AGTATGCTGG GGTTGCTTTG 1980
ACAAGGGAAC AAGCCAACAT TCTGACCATG AACGGTGATA CATTGGTATA TCCTGCTCGT 2040
TTCTCTTCTG CGAGATGGGA AGATTGGGGA GATCTGTCTC AGGTCCTTGC TGATTTCGAG 2100
CGGCCTTCTT ATCCTGATAT TCCTCCGGTT GATTTCGCAA TGGATGTGTC CAAGATGAGG 2160
AATGTTGCTT GTTACATAAG CCACAGTACT GATCCGAATG TCATTGTCCA GTTTGTACTC 2220
CATGATCACA ACAGTCTCAT GTTCCCTAGA GTCATGCTTT TCGCTGCTGA AAACATCCCT 2280
CCCATGACTG AGCTCAGCCT TGATTACGGA GTAGTTGATG ATTGGAACGC CAAGCTTGCC 2340
ATTTGTAATT AAAATTCAAC CGTTAAAATC GTGGTTCTTG GCCATATTTT CCAGTTGGTG 2400
ACATGAAGAA TGAAGGAAAG GAAGTGTGCA GAAGCTAAGG TTTAAGAGAC CCCACTCCTC 2460
CCATTTCGAG TTTTTGGGTA TCTTTGAACA TTTGGGAGTG TGTGTTTTTG GGGGTAATAG 2520
GATACAAAAC TTAAAAGCTG TTTGTTTTGT TTGTACTGTT TTGTTCTTGG GTTTGTCTCG 2580
TACTAATCAA GTAAAACAAA TGTCTCGTAC TCTATGACTC TCTCTTTCTA AATTGGTATT 2640
AGATGAAATT ACACCATATA TTTTGATGAA AAACATTTGC GTTCAATCGT 2691
Sequence Source Ensembl
Keyword

KW-0002--3D-structure
KW-0137--Centromere
KW-0156--Chromatin regulator
KW-0158--Chromosome
KW-0181--Complete proteome
KW-0238--DNA-binding
KW-0479--Metal-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0862--Zinc
--
Interpro

IPR025794--Hist-Lys_N-MeTrfase_plant
IPR007728--Pre-SET_dom
IPR015947--PUA-like_domain
IPR001214--SET_dom
IPR003105--SRA_YDG
PROSITE

PS50867--PRE_SET
PS51575--SAM_MT43_SUVAR39_2
PS50280--SET
PS51015--YDG
Pfam

PF05033--Pre-SET
PF02182--SAD_SRA
PF00856--SET
Gene Ontology

GO:0000775--C:chromosome, centromeric region
GO:0005634--C:nucleus
GO:0003677--F:DNA binding
GO:0018024--F:histone-lysine N-methyltransferase activity
GO:0008270--F:zinc ion binding
GO:0009294--P:DNA mediated transformation
Orthology
WERAM ID Ensembl Protein ID Species Identity E-value Score
WERAM-Arl-0041 fgenesh1_pm.C_scaffold_9000002 Arabidopsis lyrata 89 0.0 1130
WERAM-Bro-0154 Bo8g083410.1 Brassica oleracea 75 0.0 941
WERAM-Brr-0035 Bra007048.1-P Brassica rapa 74 0.0 934
WERAM-Pot-0114 POPTR_0010s07480.1 Populus trichocarpa 64 0.0 808
WERAM-Thc-0056 EOY06233 Theobroma cacao 63 0.0 796
WERAM-Prp-0044 EMJ28171 Prunus persica 64 0.0 788
WERAM-Viv-0026 VIT_05s0049g02220.t01 Vitis vinifera 61 0.0 762
WERAM-Sot-0087 PGSC0003DMT400075191 Solanum tuberosum 59 0.0 752
WERAM-Sol-0144 Solyc12g096990.1.1 Solanum lycopersicum 57 0.0 741
WERAM-Glm-0079 GLYMA07G19420.1 Glycine max 58 0.0 726
WERAM-Met-0016 KEH40794 Medicago truncatula 57 0.0 683
WERAM-Orb-0074 OBART07G12290.1 Oryza barthii 53 2e-174 610
WERAM-Ori-0084 BGIOSGA025596-PA Oryza indica 53 4e-174 608
WERAM-Ors-0067 OS07T0435900-01 Oryza sativa 53 6e-174 608
WERAM-Lep-0075 LPERR07G10390.1 Leersia perrieri 53 1e-173 607
WERAM-Brd-0015 BRADI1G29010.1 Brachypodium distachyon 53 2e-173 607
WERAM-Orm-0070 OMERI07G09810.1 Oryza meridionalis 53 3e-173 606
WERAM-Orr-0076 ORUFI07G12410.1 Oryza rufipogon 53 7e-173 604
WERAM-Orgl-0071 OGLUM07G11790.1 Oryza glumaepatula 53 7e-173 604
WERAM-Orp-0072 OPUNC07G10970.1 Oryza punctata 53 2e-172 603
WERAM-Sei-0110 Si029125m Setaria italica 53 7e-172 601
WERAM-Sob-0021 Sb02g010210.1 Sorghum bicolor 53 1e-171 600
WERAM-Tra-0051 Traes_2AS_A204857F71.1 Triticum aestivum 52 5e-171 598
WERAM-Tru-0091 TRIUR3_32787-P1 Triticum urartu 53 1e-170 597
WERAM-Zem-0024 GRMZM2G034288_P01 Zea mays 53 2e-170 597
WERAM-Hov-0102 MLOC_71915.1 Hordeum vulgare 52 2e-170 596
WERAM-Orl-0087 KN539973.1_FGP004 Oryza longistaminata 59 1e-165 580
WERAM-Orbr-0083 OB07G18500.1 Oryza brachyantha 58 2e-164 576
WERAM-Mua-0084 GSMUA_Achr5P13120_001 Musa acuminata 51 6e-161 565
WERAM-Amt-0043 ERN15731 Amborella trichopoda 50 2e-148 523
WERAM-Org-0094 ORGLA08G0193900.1 Oryza glaberrima 46 3e-126 450
WERAM-Orni-0096 ONIVA09G01180.1 Oryza nivara 46 3e-126 449
WERAM-Aet-0062 EMT00374 Aegilops tauschii 36 6e-96 349
WERAM-Sem-0004 EFJ22703 Selaginella moellendorffii 40 9e-93 338
WERAM-Php-0129 PP1S9_150V6.1 Physcomitrella patens 40 5e-90 329
Created Date 25-Jun-2016