WERAM Information

Tag Content
WERAM ID WERAM-Art-0068
Ensembl Protein ID AT3G11200.1
Uniprot Accession Q9SRM4; ALFL2_ARATH
Genbank Protein ID NP_187729.1
Protein Name PHD finger protein ALFIN-LIKE 2
Genbank Nucleotide ID NM_111955.2
Gene Name ALFL2;AL2At3g11200;F11B9.12;F9F8.2
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
AT3G11200 AT3G11200.1 AT3G11200.1
AT3G11200 AT3G11200.2 AT3G11200.2
Details
Type Family Domain Substrates AA References (PMIDs)
Me_Reader PHD PHD-type H3K4me3/2 K 19154204
Status Reviewed
Classification
Type Family E-value Score Start End
Me_Reader PHD 2.40e-10 41.2 191 241
Organism Arabidopsis thaliana
NCBI Taxa ID 3702
Functional Description
(View)		 Histone-binding component that specifically recognizes H3 tails trimethylated on 'Lys-4' (H3K4me3), which mark transcription start sites of virtually all active genes.
Domain Profile
  Me_Reader PHD
      PHD.txt   2 tiClvCgkddegekemvqCdeCddwfHlkCvklplsslpegkswyCpsCke 52 
                  t+C  Cg ++++e+++++Cd C++w+H+kCvk++  ++++ k++ Cp C +
  AT3G11200.1 191 TLCGSCGGHYTNEEFWICCDVCERWYHGKCVKITPAKAESIKQYKCPPCCA 241
                  78********************************555554489******75 PP
Protein Sequence
(Fasta)		MAAAAVSSNP RTVEEIFKDY SARRAALLRA LTKDVDDFYS QCDPEKENLC LYGHPNESWE 60
VNLPAEEVPP ELPEPALGIN FARDGMQRKD WLSLVAVHSD CWLLSVSFYF GARLNRNERK 120
RLFSLINDLP TLFDVVTGRK AMKDNKPSSD SGSKSRNGTK RSIDGQTKSS TPKLMEESYE 180
EEEEEDEHGD TLCGSCGGHY TNEEFWICCD VCERWYHGKC VKITPAKAES IKQYKCPPCC 240
AKKGRQ 246
Nucleotide Sequence
(Fasta)		CCCAAAAATA AAAATAAAGT TTTTATTTTC TCTCTCTCTC TTATTTTTCT TCTCCTTCTT 60
GTTCCGTCTG CTTCTCTCCA TCTCCTTCCA TATCTATTGT TCTCTCTCTC TTCATGCCCG 120
AACGCATCGG GTCTCAAAAA CCATTGATAC AGACATCGAT CCTTGTCAAC TAGTACTGAT 180
CTATAAATCT TATAAAAATC TGTAGAGATA TGGCCGCCGC AGCCGTTTCC TCTAACCCTC 240
GCACCGTTGA AGAGATCTTC AAAGATTATT CCGCTCGTCG TGCCGCTCTT CTTCGTGCTC 300
TCACTAAAGA TGTTGATGAT TTTTACTCTC AATGCGATCC GGAAAAGGAG AATTTGTGTT 360
TGTACGGACA CCCTAATGAG TCATGGGAAG TGAATCTACC AGCAGAGGAA GTGCCTCCGG 420
AGCTACCTGA GCCTGCTCTT GGTATCAATT TCGCTAGAGA TGGTATGCAG AGGAAAGATT 480
GGCTTTCTCT TGTTGCTGTT CACAGTGATT GTTGGTTGCT CTCTGTTTCT TTCTACTTTG 540
GAGCCCGTCT TAATCGCAAT GAGAGGAAGC GGTTATTCAG TCTGATCAAC GATCTCCCAA 600
CTCTCTTCGA TGTAGTGACT GGTAGGAAAG CCATGAAAGA CAACAAGCCA AGCTCGGACT 660
CAGGAAGCAA ATCCAGAAAT GGCACTAAGA GATCAATAGA CGGGCAGACA AAGAGCTCAA 720
CACCGAAACT AATGGAAGAG AGCTATGAGG AGGAGGAAGA AGAAGACGAG CATGGAGACA 780
CTCTCTGTGG AAGCTGTGGA GGTCATTACA CAAATGAGGA GTTCTGGATT TGCTGTGATG 840
TTTGTGAACG TTGGTACCAT GGAAAATGCG TCAAGATAAC TCCGGCTAAA GCAGAGAGCA 900
TCAAGCAGTA TAAATGCCCG CCTTGCTGTG CAAAGAAAGG AAGACAGTGA TGCTGATCAA 960
TTGATGATGA TGATGATGAT GATCTCTCAG AGAGACTCTG GTTCTCATGT TTTAATCAAT 1020
ATGTTAATCA ACTTTTTTTC TTTTCTTCTC TTTTTTTCTT TAACCTTCTT AATTTTAAAG 1080
CATACAAAAC TCTCTCTTTA GATCTCAAGA AAGGGATTTC AAGAAGTTGA GGGAGAGAGT 1140
AGCAAACTGT TTGAATAATA TTATTATTAT TCATATTAAA AAAAAAAAAA CTGGGTTGTG 1200
TCATCAATTG TGTTGTGTCA TGGGGTTTGT ATATGTTAGA CTTAGTCAAA TCTTTAAGCT 1260
TCGAACCGAA TTTTGAACAA ATATGTTTTT AATC 1295
Sequence Source Ensembl
Keyword

KW-0007--Acetylation
KW-0025--Alternative splicing
KW-0156--Chromatin regulator
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0804--Transcription
KW-0805--Transcription regulation
KW-0862--Zinc
KW-0863--Zinc-finger
--
Interpro

IPR021998--Alfin
IPR019786--Zinc_finger_PHD-type_CS
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD
PROSITE

PS01359--ZF_PHD_1
PS50016--ZF_PHD_2
Pfam

PF12165--DUF3594
PF00628--PHD
Gene Ontology

GO:0005829--C:cytosol
GO:0005634--C:nucleus
GO:0008270--F:zinc ion binding
GO:0016568--P:chromatin modification
GO:0006355--P:regulation of transcription, DNA-templated
GO:0006351--P:transcription, DNA-templated
Orthology
WERAM ID Ensembl Protein ID Species Identity E-value Score
WERAM-Arl-0058 fgenesh2_kg.3__ 1160__ AT3G11200.1 Arabidopsis lyrata 98 3e-115 411
WERAM-Brr-0171 Bra034860.1-P Brassica rapa 91 1e-107 386
WERAM-Bro-0019 Bo1g141160.1 Brassica oleracea 91 1e-105 379
WERAM-Prp-0085 EMJ19499 Prunus persica 79 3e-89 325
WERAM-Sot-0075 PGSC0003DMT400059399 Solanum tuberosum 78 4e-89 324
WERAM-Thc-0118 EOY17763 Theobroma cacao 79 1e-87 320
WERAM-Amt-0010 ERN05231 Amborella trichopoda 75 5e-87 317
WERAM-Sol-0125 Solyc10g076690.1.1 Solanum lycopersicum 74 2e-86 315
WERAM-Viv-0060 VIT_08s0105g00360.t01 Vitis vinifera 77 4e-86 314
WERAM-Glm-0003 GLYMA01G29950.1 Glycine max 77 5e-86 314
WERAM-Met-0150 KEH23172 Medicago truncatula 77 6e-86 314
WERAM-Mua-0107 GSMUA_Achr7P15530_001 Musa acuminata 74 7e-86 313
WERAM-Pot-0074 POPTR_0006s10180.1 Populus trichocarpa 79 7e-84 307
WERAM-Ors-0066 OS07T0233300-01 Oryza sativa 69 1e-78 289
WERAM-Orr-0075 ORUFI07G08080.1 Oryza rufipogon 69 1e-78 289
WERAM-Ori-0080 BGIOSGA024567-PA Oryza indica 69 1e-78 289
WERAM-Orni-0073 ONIVA07G06790.1 Oryza nivara 69 2e-78 289
WERAM-Orm-0069 OMERI07G06560.1 Oryza meridionalis 69 4e-78 288
WERAM-Orgl-0051 OGLUM05G06240.1 Oryza glumaepatula 69 4e-78 288
WERAM-Org-0074 ORGLA07G0067800.1 Oryza glaberrima 69 4e-78 288
WERAM-Lep-0074 LPERR07G06880.1 Leersia perrieri 69 6e-78 287
WERAM-Orp-0071 OPUNC07G07630.1 Oryza punctata 69 1e-77 286
WERAM-Orbr-0082 OB07G15980.1 Oryza brachyantha 68 2e-76 282
WERAM-Sei-0134 Si037171m Setaria italica 65 2e-76 282
WERAM-Sob-0020 Sb02g006980.1 Sorghum bicolor 67 3e-76 281
WERAM-Zem-0003 AC225147.4_FGP003 Zea mays 67 1e-75 280
WERAM-Php-0090 PP1S371_53V6.1 Physcomitrella patens 67 3e-75 278
WERAM-Brd-0027 BRADI1G53660.1 Brachypodium distachyon 65 8e-74 273
WERAM-Orb-0041 OBART03G38930.1 Oryza barthii 65 1e-73 273
WERAM-Sem-0105 EFJ23237 Selaginella moellendorffii 66 2e-73 272
WERAM-Orl-0033 KN538803.1_FGP006 Oryza longistaminata 65 4e-72 268
WERAM-Hov-0103 MLOC_72504.1 Hordeum vulgare 63 1e-71 266
WERAM-Tra-0033 Traes_1DS_59542CFCE.1 Triticum aestivum 63 3e-71 265
WERAM-Aet-0099 EMT23706 Aegilops tauschii 56 3e-66 248
Created Date 25-Jun-2016