| Tag |
Content |
| WERAM ID |
WERAM-Sac-0052 |
| Ensembl Protein ID |
YPR031W |
| Uniprot Accession |
Q12311; NTO1_YEAST; D6W441
|
| Genbank Protein ID |
NP_015356.1
|
| Protein Name |
NuA3 HAT complex component NTO1 |
| Genbank Nucleotide ID |
NM_001184128.1
|
| Gene Name |
Nto1;YPR031W |
| Ensembl Information |
|
| Details |
| Type |
Family |
Domain |
Substrates |
AA |
References (PMIDs) |
| Me_Reader |
PHD |
PHD-type |
H3K36me3 |
K |
17142463
|
|
| Status |
Reviewed |
| Classification |
| Type |
Family |
E-value |
Score |
Start |
End |
| Me_Reader |
PHD |
3.20e-10 |
38.5 |
222 |
406 |
|
| Organism |
Saccharomyces cerevisiae |
| NCBI Taxa ID |
559292 |
Functional Description
(View)Functional Description
Component of the NuA3 histone acetyltransferase complex, that acetylates Lys-14 of histone H3. Recruitment of NuA3 to nucleosomes requires methylated histone H3. In conjunction with the FACT complex, NuA3 may be involved in transcriptional regulation. |
Component of the NuA3 histone acetyltransferase complex, that acetylates Lys-14 of histone H3. Recruitment of NuA3 to nucleosomes requires methylated histone H3. In conjunction with the FACT complex, NuA3 may be involved in transcriptional regulation.
|
| Domain Profile |
Me_Reader PHD
PHD.txt 25 dwfHl 29
+wfH+
YPR031W 222 EWFHI 226
7***7 PP
PHD.txt 2 tiClvC.gkddegekemvqCdeCddwfHlkCvklplsslpegkswyCpsCk 51
+ C vC g+d+++ +++v Cd+Cd ++H++C+++ +peg +w+C++C+
YPR031W 264 QACAVClGTDSDNLNTIVFCDGCDIAVHQECYGII--FIPEG-KWLCRRCM 311
67****7788888888*******************..*****.*******8 PP
PHD.txt 3 iClvCgkddegekemvqCdeCddwfHlkCv 32
+Cl+C +++g+ + q d+++ w+H C
YPR031W 319 TCLMC-PSHTGA--FKQTDTGS-WVHNICA 344
68888.555553..44566666.9999996 PP
PHD.txt 4 ClvCgkddegekemvqCde..CddwfHlkCvklp 35
C++C k++ g+ ++qC + C +++H++C +
YPR031W 376 CYIC-KKKMGA--CIQCFQrnCFTAYHVTCARRA 406
****.666664..9***8889*********9766 PP
|
Protein Sequence
(Fasta) | MNRGSLDDGP KLREEKHFQD FYPDLNADTL LPFIVPLVET KDNSTDTDSD DISNRNNREI 60
GSVKSVQTKE LIFKGRVTTE PLVLKKNEVE FQKCKITTNE LKGKKNPYCV RFNESFISRY 120
YHINKVRNRK SYKQQQKEFD GVEAPYFTKF SSKEAPNITI STSTKSAIQK FASISPNLVN 180
FKPQYDMDEQ DELYLHYLNK RYFKDQMSHE IFEILMTTLE TEWFHIEKHI PSTNSLIARH 240
NILRDCKNYE LYGSDDGTGL SMDQACAVCL GTDSDNLNTI VFCDGCDIAV HQECYGIIFI 300
PEGKWLCRRC MISKNNFATC LMCPSHTGAF KQTDTGSWVH NICALWLPEL YFSNLHYMEP 360
IEGVQNVSVS RWKLNCYICK KKMGACIQCF QRNCFTAYHV TCARRAGLYM SKGKCTIQEL 420
ASNQFSQKYS VESFCHKHAP RGWQTSIEGI NKARKYFSLL STLQTETPQH NEANDRTNSK 480
FNKTIWKTPN QTPVAPHVFA EILQKVVDFF GLANPPAGAF DICKYWSMKR ELTGGTPLTA 540
CFENNSLGSL TEEQVQTRID FANDQLEDLY RLKELTTLVK KRTQASNSLS RSRKKVFDIV 600
KSPQKYLLKI NVLDIFIKSE QFKALERLVT EPKLLVILEK CKHCDFDTVQ IFKEEIMHFF 660
EVLETLPGAS RILQTVSSKA KEQVTNLIGL IEHVDIKKLL SRDFIINDDK IEERPWSGPV 720
IMEEEGLSDA EELSAGEHRM LKLILNSG 748Protein Fasta Sequence
>YPR031W|Nto1;YPR031W|Saccharomyces cerevisiae
MNRGSLDDGPKLREEKHFQDFYPDLNADTLLPFIVPLVETKDNSTDTDSDDISNRNNREIGSVKSVQTKELIFKGRVTTEPLVLKKNEVEFQKCKITTNELKGKKNPYCVRFNESFISRYYHINKVRNRKSYKQQQKEFDGVEAPYFTKFSSKEAPNITISTSTKSAIQKFASISPNLVNFKPQYDMDEQDELYLHYLNKRYFKDQMSHEIFEILMTTLETEWFHIEKHIPSTNSLIARHNILRDCKNYELYGSDDGTGLSMDQACAVCLGTDSDNLNTIVFCDGCDIAVHQECYGIIFIPEGKWLCRRCMISKNNFATCLMCPSHTGAFKQTDTGSWVHNICALWLPELYFSNLHYMEPIEGVQNVSVSRWKLNCYICKKKMGACIQCFQRNCFTAYHVTCARRAGLYMSKGKCTIQELASNQFSQKYSVESFCHKHAPRGWQTSIEGINKARKYFSLLSTLQTETPQHNEANDRTNSKFNKTIWKTPNQTPVAPHVFAEILQKVVDFFGLANPPAGAFDICKYWSMKRELTGGTPLTACFENNSLGSLTEEQVQTRIDFANDQLEDLYRLKELTTLVKKRTQASNSLSRSRKKVFDIVKSPQKYLLKINVLDIFIKSEQFKALERLVTEPKLLVILEKCKHCDFDTVQIFKEEIMHFFEVLETLPGASRILQTVSSKAKEQVTNLIGLIEHVDIKKLLSRDFIINDDKIEERPWSGPVIMEEEGLSDAEELSAGEHRMLKLILNSG |
Nucleotide Sequence
(Fasta) | ATGAATAGGG GATCATTAGA TGATGGGCCT AAACTACGTG AAGAAAAGCA CTTCCAAGAT 60
TTTTATCCTG ATCTTAATGC CGATACTTTA CTGCCGTTCA TCGTTCCCTT AGTGGAAACA 120
AAGGATAACA GCACCGATAC TGACTCAGAT GATATTTCAA ATCGGAATAA CAGAGAGATC 180
GGGAGTGTCA AAAGCGTACA AACTAAAGAA TTGATTTTCA AGGGGAGAGT CACCACTGAA 240
CCACTAGTAC TGAAGAAGAA CGAAGTGGAA TTTCAAAAAT GTAAAATAAC TACGAATGAG 300
TTAAAAGGTA AGAAAAATCC ATACTGCGTT AGATTTAATG AGAGCTTTAT ATCCAGGTAC 360
TATCATATAA ACAAAGTAAG AAATAGGAAG AGTTATAAAC AACAACAAAA AGAATTCGAT 420
GGTGTGGAGG CACCCTACTT CACCAAATTC TCTAGTAAAG AAGCCCCGAA TATTACTATT 480
TCGACGAGTA CAAAGAGTGC AATTCAGAAA TTCGCTAGTA TTTCACCCAA TCTTGTTAAT 540
TTCAAGCCTC AGTATGACAT GGATGAACAG GATGAATTAT ATTTGCACTA CCTTAATAAG 600
AGGTATTTTA AAGATCAAAT GTCTCACGAA ATATTTGAAA TTTTAATGAC TACACTAGAA 660
ACTGAATGGT TCCATATTGA AAAACATATA CCCTCAACGA ATAGTCTGAT TGCTAGGCAT 720
AATATTCTAA GGGACTGTAA GAATTATGAG CTATATGGTT CTGATGATGG AACAGGTTTA 780
TCGATGGACC AGGCGTGTGC AGTTTGTTTA GGCACAGACA GTGACAATCT GAATACAATT 840
GTCTTTTGTG ATGGATGCGA TATTGCTGTG CATCAAGAAT GTTACGGTAT AATTTTTATC 900
CCGGAAGGAA AATGGTTATG TAGACGATGT ATGATCTCAA AAAATAACTT TGCCACTTGT 960
CTAATGTGTC CAAGTCATAC AGGTGCATTC AAACAAACAG ACACCGGTTC TTGGGTACAT 1020
AACATTTGTG CTCTATGGCT TCCAGAGCTA TACTTTTCAA ACTTACATTA TATGGAACCT 1080
ATAGAAGGCG TTCAAAATGT TAGCGTATCA CGATGGAAAC TTAACTGCTA CATCTGTAAA 1140
AAGAAGATGG GTGCTTGCAT TCAGTGCTTT CAAAGAAACT GTTTTACAGC ATATCATGTC 1200
ACGTGTGCCC GTCGAGCTGG TCTCTACATG AGTAAAGGGA AATGCACTAT TCAAGAATTG 1260
GCCTCTAATC AATTCTCCCA AAAGTATTCA GTCGAAAGTT TCTGCCACAA GCATGCACCT 1320
AGAGGATGGC AAACGAGTAT AGAAGGTATT AATAAAGCTA GAAAATACTT CTCTCTACTC 1380
TCTACATTAC AAACCGAAAC TCCTCAGCAT AATGAAGCTA ATGATAGGAC AAATTCAAAA 1440
TTCAACAAAA CAATTTGGAA AACACCTAAT CAAACGCCGG TAGCACCACA TGTTTTTGCT 1500
GAAATATTGC AAAAGGTCGT TGATTTTTTT GGCTTAGCTA ACCCACCAGC AGGCGCATTT 1560
GATATTTGCA AATATTGGTC AATGAAAAGG GAGCTTACAG GAGGTACCCC ATTAACTGCC 1620
TGTTTTGAAA ATAATTCATT GGGGTCCTTA ACCGAGGAAC AAGTGCAAAC AAGAATAGAT 1680
TTTGCCAATG ATCAGCTCGA AGACTTGTAC CGGCTCAAAG AGCTGACTAC TTTGGTGAAA 1740
AAGAGAACAC AAGCTTCAAA CAGCTTGTCC AGATCCCGAA AGAAGGTTTT TGATATAGTT 1800
AAATCGCCCC AAAAATATCT TTTAAAAATC AATGTACTGG ATATCTTTAT AAAATCTGAA 1860
CAATTCAAGG CTCTTGAAAG ATTGGTTACT GAACCTAAAT TATTGGTTAT TTTAGAAAAG 1920
TGTAAACATT GTGATTTTGA TACTGTCCAA ATTTTTAAGG AGGAAATTAT GCATTTTTTT 1980
GAGGTTTTGG AAACTCTACC CGGTGCATCA AGAATACTCC AAACTGTCTC ATCAAAGGCA 2040
AAAGAGCAAG TAACAAATTT AATTGGGCTC ATAGAACATG TAGATATTAA GAAGTTGCTA 2100
TCCAGAGATT TTATAATAAA TGATGACAAG ATAGAAGAAA GACCATGGAG TGGCCCGGTG 2160
ATTATGGAAG AAGAAGGTTT AAGCGATGCA GAAGAACTGA GTGCAGGGGA ACACCGTATG 2220
CTGAAGCTAA TCCTTAACAG CGGATAA
2248Nucleotide Fasta Sequence
>YPR031W|PHD|Saccharomyces cerevisiae
ATGAATAGGGGATCATTAGATGATGGGCCTAAACTACGTGAAGAAAAGCACTTCCAAGATTTTTATCCTGATCTTAATGCCGATACTTTACTGCCGTTCATCGTTCCCTTAGTGGAAACAAAGGATAACAGCACCGATACTGACTCAGATGATATTTCAAATCGGAATAACAGAGAGATCGGGAGTGTCAAAAGCGTACAAACTAAAGAATTGATTTTCAAGGGGAGAGTCACCACTGAACCACTAGTACTGAAGAAGAACGAAGTGGAATTTCAAAAATGTAAAATAACTACGAATGAGTTAAAAGGTAAGAAAAATCCATACTGCGTTAGATTTAATGAGAGCTTTATATCCAGGTACTATCATATAAACAAAGTAAGAAATAGGAAGAGTTATAAACAACAACAAAAAGAATTCGATGGTGTGGAGGCACCCTACTTCACCAAATTCTCTAGTAAAGAAGCCCCGAATATTACTATTTCGACGAGTACAAAGAGTGCAATTCAGAAATTCGCTAGTATTTCACCCAATCTTGTTAATTTCAAGCCTCAGTATGACATGGATGAACAGGATGAATTATATTTGCACTACCTTAATAAGAGGTATTTTAAAGATCAAATGTCTCACGAAATATTTGAAATTTTAATGACTACACTAGAAACTGAATGGTTCCATATTGAAAAACATATACCCTCAACGAATAGTCTGATTGCTAGGCATAATATTCTAAGGGACTGTAAGAATTATGAGCTATATGGTTCTGATGATGGAACAGGTTTATCGATGGACCAGGCGTGTGCAGTTTGTTTAGGCACAGACAGTGACAATCTGAATACAATTGTCTTTTGTGATGGATGCGATATTGCTGTGCATCAAGAATGTTACGGTATAATTTTTATCCCGGAAGGAAAATGGTTATGTAGACGATGTATGATCTCAAAAAATAACTTTGCCACTTGTCTAATGTGTCCAAGTCATACAGGTGCATTCAAACAAACAGACACCGGTTCTTGGGTACATAACATTTGTGCTCTATGGCTTCCAGAGCTATACTTTTCAAACTTACATTATATGGAACCTATAGAAGGCGTTCAAAATGTTAGCGTATCACGATGGAAACTTAACTGCTACATCTGTAAAAAGAAGATGGGTGCTTGCATTCAGTGCTTTCAAAGAAACTGTTTTACAGCATATCATGTCACGTGTGCCCGTCGAGCTGGTCTCTACATGAGTAAAGGGAAATGCACTATTCAAGAATTGGCCTCTAATCAATTCTCCCAAAAGTATTCAGTCGAAAGTTTCTGCCACAAGCATGCACCTAGAGGATGGCAAACGAGTATAGAAGGTATTAATAAAGCTAGAAAATACTTCTCTCTACTCTCTACATTACAAACCGAAACTCCTCAGCATAATGAAGCTAATGATAGGACAAATTCAAAATTCAACAAAACAATTTGGAAAACACCTAATCAAACGCCGGTAGCACCACATGTTTTTGCTGAAATATTGCAAAAGGTCGTTGATTTTTTTGGCTTAGCTAACCCACCAGCAGGCGCATTTGATATTTGCAAATATTGGTCAATGAAAAGGGAGCTTACAGGAGGTACCCCATTAACTGCCTGTTTTGAAAATAATTCATTGGGGTCCTTAACCGAGGAACAAGTGCAAACAAGAATAGATTTTGCCAATGATCAGCTCGAAGACTTGTACCGGCTCAAAGAGCTGACTACTTTGGTGAAAAAGAGAACACAAGCTTCAAACAGCTTGTCCAGATCCCGAAAGAAGGTTTTTGATATAGTTAAATCGCCCCAAAAATATCTTTTAAAAATCAATGTACTGGATATCTTTATAAAATCTGAACAATTCAAGGCTCTTGAAAGATTGGTTACTGAACCTAAATTATTGGTTATTTTAGAAAAGTGTAAACATTGTGATTTTGATACTGTCCAAATTTTTAAGGAGGAAATTATGCATTTTTTTGAGGTTTTGGAAACTCTACCCGGTGCATCAAGAATACTCCAAACTGTCTCATCAAAGGCAAAAGAGCAAGTAACAAATTTAATTGGGCTCATAGAACATGTAGATATTAAGAAGTTGCTATCCAGAGATTTTATAATAAATGATGACAAGATAGAAGAAAGACCATGGAGTGGCCCGGTGATTATGGAAGAAGAAGGTTTAAGCGATGCAGAAGAACTGAGTGCAGGGGAACACCGTATGCTGAAGCTAATCCTTAACAGCGGATAA
|
| Sequence Source |
Ensembl |
| Keyword |
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0479--Metal-binding
KW-0539--Nucleus
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0804--Transcription
KW-0805--Transcription regulation
KW-0862--Zinc
KW-0863--Zinc-finger
--
|
| Interpro |
IPR019542--Enhancer_polycomb-like_N
IPR019786--Zinc_finger_PHD-type_CS
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD
|
| PROSITE |
PS01359--ZF_PHD_1
PS50016--ZF_PHD_2
|
| Pfam |
PF10513--EPL1
|
| Gene Ontology |
GO:0005737--C:cytoplasm
GO:0033100--C:NuA3 histone acetyltransferase complex
GO:1990467--C:NuA3a histone acetyltransferase complex
GO:1990468--C:NuA3b histone acetyltransferase complex
GO:0035064--F:methylated histone binding
GO:0008270--F:zinc ion binding
GO:0016573--P:histone acetylation
GO:0006355--P:regulation of transcription, DNA-templated
GO:0006351--P:transcription, DNA-templated
|
| Orthology |
|
| Created Date |
25-Jun-2016 |
