WERAM Information

Tag Content
WERAM ID WERAM-Drm-0047
Ensembl Protein ID FBpp0080629
Uniprot Accession Q9VJ73; Q9VJ73_DROME
Genbank Protein ID NP_609889.1
Protein Name Ada2a-containing complex component 2
Genbank Nucleotide ID NM_136045.3
Gene Name ATAC2;KAT14;CG10414;Dmel_CG10414
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
FBgn0032691 FBtr0081079 FBpp0080629
Details
Type Family Domain Substrates AA References (PMIDs)
HAT GNAT_other N-acetyltransferase H4K16 K 23535028; 22345504
Status Reviewed
Classification
Type Family E-value Score Start End
HAT GNAT_other 3.80e-70 235.4 630 768
Organism Drosophila melanogaster
NCBI Taxa ID 7227
Functional Description
(View)
Domain Profile
  HAT GNAT_other
  GNATOTHER.txt   1 ldesfvrpvdirtindliqevlypgidlsecLdyddfsvvvlekkvviasgflvrdvgyneaeisllavrskyrraGiarilvyalietlmskdvt 96 
                    +d++fvrp++i+++n+l+q++++p+id+secL+y+d+svv+l+kk+vi++gflv+dvgynea+is++avr++++r+Gia++++y+li+t+mskd+t
    FBpp0080629 630 IDFCFVRPQHIPAVNALLQSTFWPNIDVSECLSYPDYSVVALYKKLVIGCGFLVPDVGYNEAYISFMAVRPCWQRSGIASFMLYHLIQTCMSKDIT 725
                    79********************************************************************************************** PP
  GNATOTHER.txt  97 llvsaanpalllyekfGfkmeeevlDfydkyfPlesllkktly 139
                    l+vsa+n+a++ly+kfGfkmee++lDfydky+Pl+s + ++++
    FBpp0080629 726 LHVSATNAAVMLYQKFGFKMEEIILDFYDKYLPLDSKQSRNAF 768
                    ************************************9988876 PP
Protein Sequence
(Fasta)		MNRPSNWDDP QGPCRYCESP VEDDNYLECQ ECRRMVHIKC LPHACTPGDL LGDVFFEFTC 60
VKCVLDKAKE SVIPSDLEPI KEVIVRQRIP WLLVLTLTLY NLSIKQKGLG HHGFFHWRTH 120
IISFVDKNWN YIFGPNVRRR KQWTGSVSGA LSHNSPEYFQ SGLDVFQENG WWKLAKPFQT 180
PRSVLKEYEK KQQLRLQMRI EKRLPAADET SCSSEISVAD HAQDNPPLIK AEAEKPSSTE 240
GCARTIPYMG RLPKIQTQPS PLSQETLPGP PILQENIAPP SQKEEEPQNQ PMSMVQAGLM 300
DFLAESLESD DFTMFGNLPG IMPPPLIGAG KNDFFMTEPL LHAPLNNEGL FDMDTNFAIP 360
NTADETKPIS TEEPAAESSE EQKEGEVEDE KPEEDESPDY QPRIVQVTNY QAQEANESIK 420
EEPLEEIMQD DDVTTNSKSS ILEPCKPSGF VRQPRRNWPW LQEAQDPDDM AIPSENLKLI 480
NAYEEQKLYQ RLDRIFALEH QCHISIPAYV RRLYRKLSLR KWKRDHNRHI FNLDEHIDPL 540
GRARLKMLGH QKAEILDRYQ LLAHSRQDAR SSFHARLAGC TQYELFESPY SQRVLHPFIF 600
RSETMAPPWL KLMCELQHRV NGSHPTRSTI DFCFVRPQHI PAVNALLQST FWPNIDVSEC 660
LSYPDYSVVA LYKKLVIGCG FLVPDVGYNE AYISFMAVRP CWQRSGIASF MLYHLIQTCM 720
SKDITLHVSA TNAAVMLYQK FGFKMEEIIL DFYDKYLPLD SKQSRNAFFL RLQR 774
Nucleotide Sequence
(Fasta)		GGTAACACAC AAACAACACA TTATTTTGTT GATTGTTTTT AACTTGCAAT TTGTGCTGTT 60
TTACTGAGTA AATGAATCGG CCCAGTAACT GGGATGATCC CCAGGGACCA TGCCGCTACT 120
GTGAATCGCC GGTGGAGGAC GACAACTACC TGGAGTGCCA GGAATGCAGG CGGATGGTTC 180
ACATCAAATG CCTGCCGCAT GCTTGCACGC CCGGAGATCT TTTAGGCGAC GTTTTCTTCG 240
AGTTCACGTG CGTCAAGTGT GTGCTGGATA AAGCTAAGGA ATCGGTCATA CCCTCAGATC 300
TAGAACCCAT TAAGGAAGTG ATCGTGCGCC AAAGGATACC TTGGCTGCTG GTGCTCACCC 360
TAACGCTCTA CAATCTGTCC ATCAAACAAA AGGGCTTGGG ACACCATGGA TTCTTCCATT 420
GGCGCACGCA CATCATCAGT TTTGTGGACA AGAACTGGAA CTATATATTC GGTCCCAATG 480
TGCGGCGTCG CAAGCAATGG ACTGGTTCCG TATCCGGCGC ACTGTCCCAC AACAGTCCGG 540
AGTACTTTCA GTCTGGTCTG GATGTCTTTC AGGAGAACGG CTGGTGGAAA CTGGCCAAGC 600
CCTTTCAAAC CCCAAGAAGC GTTCTCAAAG AATATGAGAA AAAGCAACAG TTGCGGCTAC 660
AAATGCGTAT TGAAAAGCGG TTGCCTGCAG CGGACGAGAC CAGCTGTAGC AGCGAGATCT 720
CAGTGGCGGA TCATGCCCAG GATAACCCAC CGCTTATTAA AGCAGAAGCT GAGAAACCCA 780
GTTCAACAGA GGGCTGTGCG CGAACAATTC CCTACATGGG CCGTTTGCCA AAGATACAAA 840
CACAACCTTC ACCCTTGTCA CAGGAAACGC TTCCAGGGCC ACCAATTCTT CAAGAAAATA 900
TAGCGCCACC AAGTCAGAAG GAGGAAGAAC CACAGAATCA GCCTATGAGC ATGGTCCAAG 960
CAGGCCTGAT GGATTTTCTG GCTGAAAGTT TGGAAAGCGA TGATTTTACC ATGTTTGGTA 1020
ACCTACCAGG CATAATGCCC CCACCCCTGA TTGGAGCGGG TAAAAATGAT TTCTTCATGA 1080
CCGAGCCGTT GCTTCACGCA CCTTTGAATA ATGAAGGTCT TTTCGACATG GATACAAATT 1140
TTGCCATACC AAATACCGCT GATGAGACCA AACCCATATC AACAGAAGAA CCTGCAGCCG 1200
AAAGCAGCGA GGAACAAAAA GAAGGCGAGG TAGAAGATGA AAAGCCAGAA GAGGACGAAT 1260
CACCCGACTA TCAGCCACGC ATCGTACAGG TTACAAATTA CCAGGCGCAA GAGGCAAACG 1320
AAAGCATCAA AGAGGAACCA CTAGAAGAGA TAATGCAAGA TGATGACGTC ACGACAAATA 1380
GCAAATCCTC TATCCTAGAG CCTTGCAAAC CGAGTGGATT TGTCAGACAA CCACGGCGAA 1440
ATTGGCCCTG GTTGCAGGAG GCGCAGGATC CCGATGACAT GGCCATTCCT AGCGAAAATC 1500
TCAAACTAAT AAATGCATAC GAAGAACAGA AGTTGTACCA GCGACTCGAT AGAATATTCG 1560
CACTGGAGCA TCAGTGCCAC ATATCCATAC CTGCCTATGT GCGGCGCCTA TATCGAAAAC 1620
TTTCTCTTCG AAAATGGAAA AGGGACCACA ATCGACACAT ATTTAACTTG GACGAGCACA 1680
TAGATCCCCT GGGAAGAGCA CGCCTAAAGA TGCTGGGTCA TCAGAAGGCC GAAATTCTTG 1740
ACAGATATCA GTTGTTAGCC CATTCACGAC AAGATGCAAG GAGCTCCTTT CACGCCCGCC 1800
TGGCGGGATG CACTCAATAC GAGCTCTTTG AATCGCCCTA CTCTCAAAGA GTTCTTCATC 1860
CATTTATCTT TCGGAGCGAA ACGATGGCTC CTCCATGGCT GAAGCTTATG TGCGAGCTGC 1920
AGCATAGAGT AAACGGATCT CATCCCACAA GATCTACCAT CGACTTCTGT TTTGTGAGAC 1980
CGCAGCATAT TCCGGCCGTA AACGCATTAC TCCAAAGTAC TTTTTGGCCA AACATTGATG 2040
TAAGCGAGTG TTTGAGCTAC CCGGACTACA GTGTAGTGGC GTTGTACAAG AAACTGGTCA 2100
TCGGTTGCGG ATTCCTAGTG CCCGACGTAG GTTACAACGA GGCCTACATC TCATTCATGG 2160
CGGTGCGGCC GTGCTGGCAA CGCAGTGGCA TCGCCAGCTT CATGTTATAT CACCTTATCC 2220
AGACATGTAT GTCCAAGGAC ATAACGTTGC ACGTTTCCGC CACCAACGCG GCCGTCATGT 2280
TGTACCAGAA ATTCGGATTT AAGATGGAGG AAATCATCTT GGACTTTTAT GACAAGTATC 2340
TGCCTCTGGA CTCGAAACAG AGCAGAAATG CCTTCTTTTT GAGATTACAA AGATGAGACT 2400
TTTTTCAAAT AAATGGTTTA TGAATCT 2428
Sequence Source Ensembl
Keyword

KW-0012--Acyltransferase
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0808--Transferase
KW-0862--Zinc
KW-0863--Zinc-finger
--
Interpro

IPR016181--Acyl_CoA_acyltransferase
IPR000182--GNAT_dom
IPR019786--Zinc_finger_PHD-type_CS
IPR011011--Znf_FYVE_PHD
IPR013083--Znf_RING/FYVE/PHD
PROSITE

PS51186--GNAT
PS01359--ZF_PHD_1
Pfam

PF13673--Acetyltransf_10
Gene Ontology

GO:0005671--C:Ada2/Gcn5/Ada3 transcription activator complex
GO:0043998--F:H2A histone acetyltransferase activity
GO:0010485--F:H4 histone acetyltransferase activity
GO:0046872--F:metal ion binding
GO:0006338--P:chromatin remodeling
GO:0016573--P:histone acetylation
GO:0043968--P:histone H2A acetylation
GO:0043967--P:histone H4 acetylation
GO:0036335--P:intestinal stem cell homeostasis
GO:2000620--P:positive regulation of histone H4-K16 acetylation
Orthology
WERAM ID Ensembl Protein ID Species Identity E-value Score
WERAM-Caf-0065 ENSCAFP00000008130.3 Canis familiaris 45 1e-75 281
WERAM-Meg-0073 ENSMGAP00000006809.2 Meleagris gallopavo 47 1e-75 281
WERAM-Gog-0118 ENSGGOP00000009870.2 Gorilla gorilla 45 1e-75 281
WERAM-Ptv-0135 ENSPVAP00000011444.1 Pteropus vampyrus 45 2e-75 281
WERAM-Dar-0094 ENSDARP00000122559.1 Danio rerio 45 2e-75 281
WERAM-Leo-0164 ENSLOCP00000019322.1 Lepisosteus oculatus 48 2e-75 281
WERAM-Aim-0065 ENSAMEP00000005555.1 Ailuropoda melanoleuca 46 2e-75 281
WERAM-Pof-0226 ENSPFOP00000018419.2 Poecilia formosa 45 2e-75 281
WERAM-Fec-0061 ENSFCAP00000005396.3 Felis catus 45 2e-75 281
WERAM-Mod-0048 ENSMODP00000006860.2 Monodelphis domestica 46 2e-75 281
WERAM-Ere-0075 ENSEEUP00000006314.1 Erinaceus europaeus 46 2e-75 281
WERAM-Gaga-0091 ENSGALP00000014153.2 Gallus gallus 47 3e-75 280
WERAM-Ran-0045 ENSRNOP00000009437.5 Rattus norvegicus 45 3e-75 280
WERAM-Pat-0106 ENSPTRP00000022781.4 Pan troglodytes 45 3e-75 280
WERAM-Tut-0188 ENSTTRP00000015573.1 Tursiops truncatus 41 3e-75 280
WERAM-Hos-0157 ENSP00000392318.2 Homo sapiens 45 4e-75 280
WERAM-Eqc-0137 ENSECAP00000015220.1 Equus caballus 46 4e-75 280
WERAM-Chs-0142 ENSCSAP00000007739.1 Chlorocebus sabaeus 45 4e-75 280
WERAM-Paa-0133 ENSPANP00000017109.1 Papio anubis 45 4e-75 280
WERAM-Cap-0144 ENSCPOP00000011814.2 Cavia porcellus 46 4e-75 280
WERAM-Poa-0090 ENSPPYP00000011998.2 Pongo abelii 45 4e-75 280
WERAM-Orc-0151 ENSOCUP00000013201.3 Oryctolagus cuniculus 45 4e-75 280
WERAM-Xim-0112 ENSXMAP00000009786.1 Xiphophorus maculatus 43 4e-75 280
WERAM-Tas-0003 ENSTSYP00000000350.1 Tarsius syrichta 46 6e-75 280
WERAM-Mam-0212 ENSMMUP00000030461.2 Macaca mulatta 45 6e-75 280
WERAM-Ora-0014 ENSOANP00000001992.1 Ornithorhynchus anatinus 46 6e-75 279
WERAM-Anp-0156 ENSAPLP00000016062.1 Anas platyrhynchos 47 7e-75 279
WERAM-Pes-0053 ENSPSIP00000007319.1 Pelodiscus sinensis 46 1e-74 279
WERAM-Anc-0152 ENSACAP00000013990.2 Anolis carolinensis 46 1e-74 278
WERAM-Mae-0105 ENSMEUP00000010205.1 Macropus eugenii 46 1e-74 278
WERAM-Mum-0085 ENSMUSP00000028911.8 Mus musculus 45 2e-74 278
WERAM-Sah-0199 ENSSHAP00000021647.1 Sarcophilus harrisii 46 2e-74 278
WERAM-Lac-0096 ENSLACP00000012192.1 Latimeria chalumnae 46 2e-74 278
WERAM-Mup-0013 ENSMPUP00000001281.1 Mustela putorius furo 45 2e-74 278
WERAM-Otg-0028 ENSOGAP00000001707.2 Otolemur garnettii 45 4e-74 276
WERAM-Dan-0066 ENSDNOP00000006490.3 Dasypus novemcinctus 45 5e-74 276
WERAM-Ect-0136 ENSETEP00000015380.1 Echinops telfairi 45 6e-74 276
WERAM-Myl-0082 ENSMLUP00000006635.2 Myotis lucifugus 45 6e-74 276
WERAM-Caj-0057 ENSCJAP00000009281.2 Callithrix jacchus 46 7e-74 276
WERAM-Sus-0048 ENSSSCP00000007555.2 Sus scrofa 45 1e-73 275
WERAM-Ova-0195 ENSOARP00000019685.1 Ovis aries 44 6e-73 273
WERAM-Loa-0064 ENSLAFP00000004745.2 Loxodonta africana 46 8e-73 272
WERAM-Asm-0038 ENSAMXP00000004864.1 Astyanax mexicanus 45 1e-72 271
WERAM-Fia-0096 ENSFALP00000007927.1 Ficedula albicollis 54 2e-71 268
WERAM-Tag-0086 ENSTGUP00000006066.1 Taeniopygia guttata 53 5e-71 266
WERAM-Soa-0107 ENSSARP00000010061.1 Sorex araneus 43 4e-70 263
WERAM-Nol-0102 ENSNLEP00000011864.1 Nomascus leucogenys 44 4e-70 263
WERAM-Orn-0078 ENSONIP00000008648.1 Oreochromis niloticus 45 7e-69 259
WERAM-Xet-0093 ENSXETP00000030216.3 Xenopus tropicalis 44 2e-68 258
WERAM-Gaa-0212 ENSGACP00000026301.1 Gasterosteus aculeatus 46 6e-68 256
WERAM-Tar-0140 ENSTRUP00000030432.1 Takifugu rubripes 44 1e-67 255
WERAM-Gam-0094 ENSGMOP00000009855.1 Gadus morhua 57 3e-66 251
WERAM-Pem-0022 ENSPMAP00000003104.1 Petromyzon marinus 53 5e-64 243
WERAM-Chh-0116 ENSCHOP00000012270.1 Choloepus hoffmanni 43 3e-62 237
WERAM-Orla-0214 ENSORLP00000025874.1 Oryzias latipes 59 5e-59 226
Created Date 25-Jun-2016