WERAM Information

Tag Content
WERAM ID WERAM-Mum-0085
Ensembl Protein ID ENSMUSP00000028911.8
Uniprot Accession Q8CID0; CSR2B_MOUSE; A2ANA8
Genbank Protein ID NP_852082.2
Protein Name Cysteine-rich protein 2-binding protein
Genbank Nucleotide ID NM_181417.3
Gene Name CSR2B;ATAC2
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSMUSG00000027425.18 ENSMUST00000028911.14 ENSMUSP00000028911.8
ENSMUSG00000027425.18 ENSMUST00000147747.7 ENSMUSP00000130785.1
Details
Type Family Domain Substrates AA References (PMIDs)
HAT GNAT_other N-acetyltransferase H3K9; H4K5; H4K12; H4K16 K 19103755
Status Reviewed
Classification
Type Family E-value Score Start End
HAT GNAT_other 2.20e-78 263 635 773
Organism Mus musculus
NCBI Taxa ID 10090
Functional Description
(View)		 Component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4. May function as a scaffold for the ATAC complex to promote ATAC complex stability. Has also weak histone acetyltransferase activity toward histone H4. Required for the normal progression through G1 and G2/M phases of the cell cycle (By similarity).
Domain Profile
  HAT GNAT_other
         GNATOTHER.txt   1 ldesfvrpvdirtindliqevlypgidlsecLdyddfsvvvlekkvviasgflvrdvgyneaeisllavrskyrraGiarilvyaliet 89 
                           ld+++vrp++i+tin+++qe+++pgidlsecL+y+dfsvvvl+kkv++a+gf+v+dv+ynea+is+l+v++++rraGia++++y+li+t
  ENSMUSP00000028911.8 635 LDYCYVRPNHIPTINSMCQEFFWPGIDLSECLQYPDFSVVVLYKKVIVAFGFMVPDVKYNEAYISFLLVHPEWRRAGIATFMIYHLIQT 723
                           79*************************************************************************************** PP
         GNATOTHER.txt  90 lmskdvtllvsaanpalllyekfGfkmeeevlDfydkyfPlesllkktly 139
                           +m+kdvtl+vsa+npa+lly+kfGfk+ee+vlDfydky+Ples+++k+++
  ENSMUSP00000028911.8 724 CMGKDVTLHVSASNPAMLLYQKFGFKTEEYVLDFYDKYYPLESTECKHAF 773
                           ************************************************98 PP
Protein Sequence
(Fasta)		MDSSIHLSGL LSRHDDDATR TSTSEGLEEG EVEGETLLIV ESEDQASVDL SHDQSGDSLN 60
SDEGDVSWME EQLSYFCDKC QKWIPASQLR EQLSYLKGDN FFRFTCCDCS ADGKEQYERL 120
KLTWQQVVML AMYNLSLEGS GRQGYFRWKE DICAFIEKHW TFLLGNRKKT STWWSTVAGC 180
LSVGSPVYFR SGAQEFGEPG WWKLVHNRPP TMRPEGEKLA ASTLKVKASK PTLDPIITVE 240
GLRKRASRNP VESAMELKEK RSRTQEAKDI RRAQKEAAGL LDRSTSSTPV KFISRGRRPD 300
LILEKGEVID FSSLSSSDRT PLTSPSPSPS LDFSAPGTPA SHSATPSLLS EADLIPDVMP 360
PQALFHDDDE LEGDGVIDPG MEYIPPPAGS ASGLLGSRKK VRAPEQIKQE VDSEEEKPDR 420
MDGDSEDTDS NISLHTRARE KRKPPLEKDM KPKGPRYTPV SIYEEKLLLK RLEACPGAVA 480
MTPEARRLKR KLIVRQAKRD RGLPLFDLDE VVNAALLLVD GIYGAKDGGA SRLAAGQATY 540
RTTCQDFRIL DRYQTALPAR KGFRHQTTRF LYRLVGSEDL AVDQSIISPY TSRILKPYIR 600
RDYETKPPKL QLLSQIRSHL HRSDPHWTPG PDAPLDYCYV RPNHIPTINS MCQEFFWPGI 660
DLSECLQYPD FSVVVLYKKV IVAFGFMVPD VKYNEAYISF LLVHPEWRRA GIATFMIYHL 720
IQTCMGKDVT LHVSASNPAM LLYQKFGFKT EEYVLDFYDK YYPLESTECK HAFFLRLRR 779
Nucleotide Sequence
(Fasta)		CGTTGCGGCT GCGGCGGCGG CGGCGGCTGT GGCGGCGGCG GGGGCGGGCG CGGGAGCGAG 60
TCCGCGGCCG GGAGCGGGAA TGTCGAGGAG TTCGAAGGCA GTGCTGGGCC TCTCGGTGCT 120
GCTGACGGCG GCCACGGTGG CCGGCGTGCA TCTGAAGCAG CGGCAGGACC GGCAGAGGCT 180
TCGTGACGGA GTGATCAGAG ACATTGAGAG GCAGAATCAG AAAAAAGAAA ACATTCGTCT 240
TCTGGGAGAA CAGATTATTT TGACTAAGCA GCTTGAAGCA GAAAGAGAGA AGATGTTGGA 300
GAAAGGATCT CAAAATACCT GACTTTCAGA AGCCGGGGGC AGCGCTGAGT TGGTGTGCGT 360
AACTGTGGGT GTGGTGTGTT GGTAGAGAGT TGTTAGTGAG AAGAGCTGCC CCCCCAAATC 420
ACGCTCCATT TAAACTTTGT TAAATGAAGG ACAGTGGGCC CTGTCTTCTA AATTGCTTCT 480
TTAAAGAGTC TGTTCTGTCT GGATAGAGTG CTTGTGGGCA GATGTCCTTC TGAAGGTCTG 540
GGGGATCCCG GCAGCTTAGG AGTGCGTGTG AGCAGGGGGC GATGGATAGT AGCATCCACC 600
TGAGTGGGCT CCTCAGTCGG CATGACGATG ACGCCACGAG AACGTCCACC TCGGAAGGGC 660
TGGAGGAAGG CGAGGTGGAG GGAGAGACTC TCCTAATTGT GGAATCGGAG GATCAGGCGT 720
CAGTGGACTT ATCTCACGAC CAGAGTGGGG ATTCCCTCAA CAGCGATGAA GGAGATGTGT 780
CCTGGATGGA GGAACAGCTG TCTTACTTCT GTGACAAGTG CCAAAAGTGG ATCCCAGCCA 840
GTCAGCTGAG GGAGCAGCTC AGTTACCTGA AGGGCGATAA CTTTTTCAGG TTTACTTGTT 900
GCGATTGCTC TGCAGACGGC AAGGAGCAGT ACGAGAGGCT GAAACTGACA TGGCAGCAAG 960
TGGTCATGCT GGCAATGTAC AACCTGTCTC TGGAAGGAAG TGGACGTCAA GGTTATTTCC 1020
GGTGGAAAGA AGATATCTGT GCTTTTATTG AGAAACATTG GACTTTTTTA CTAGGAAATA 1080
GGAAAAAGAC GTCGACGTGG TGGAGCACAG TAGCAGGCTG CCTCAGCGTG GGAAGCCCTG 1140
TTTATTTCCG GTCAGGTGCT CAGGAGTTTG GAGAGCCCGG ATGGTGGAAA CTTGTTCATA 1200
ACAGACCCCC AACCATGAGG CCGGAGGGAG AGAAGCTGGC TGCCTCCACC TTGAAAGTGA 1260
AAGCTTCAAA GCCAACGCTG GATCCCATCA TTACTGTTGA GGGACTCAGA AAACGGGCAA 1320
GCCGGAATCC TGTGGAATCT GCCATGGAAT TGAAAGAGAA GCGGTCGCGA ACACAGGAAG 1380
CTAAAGACAT CAGAAGAGCT CAGAAAGAAG CGGCTGGCCT CCTCGACAGG AGCACCTCTT 1440
CCACCCCCGT CAAGTTCATA AGCCGAGGCC GGAGGCCGGA TCTGATTTTG GAGAAAGGAG 1500
AAGTGATCGA CTTCTCGTCC CTGAGCTCCT CAGACCGCAC TCCCCTCACA AGCCCGTCTC 1560
CTTCTCCGTC TCTGGATTTC TCCGCCCCGG GGACGCCAGC CTCGCACTCG GCCACACCTA 1620
GCTTGCTTTC CGAAGCAGAC CTCATCCCAG ACGTGATGCC ACCCCAAGCC CTGTTTCATG 1680
ATGACGATGA GCTGGAAGGA GATGGAGTTA TAGACCCAGG GATGGAGTAC ATCCCACCCC 1740
CAGCTGGGTC AGCGTCTGGG CTGCTTGGGA GCAGAAAGAA GGTCCGAGCT CCGGAACAGA 1800
TAAAACAGGA AGTGGACAGC GAGGAGGAGA AGCCAGACAG GATGGATGGA GATAGCGAAG 1860
ACACAGATTC AAACATTTCT CTGCACACTA GAGCTCGAGA AAAGAGGAAG CCGCCACTGG 1920
AAAAGGACAT GAAGCCCAAG GGCCCCAGGT ATACACCCGT GAGCATCTAT GAGGAGAAGC 1980
TGCTGCTCAA GAGGCTGGAG GCGTGCCCCG GCGCCGTGGC CATGACTCCA GAAGCCAGGA 2040
GGCTGAAACG GAAACTGATC GTCCGGCAAG CGAAAAGAGA TCGGGGTTTA CCACTATTTG 2100
ACTTGGACGA GGTTGTGAAT GCCGCACTTC TGTTAGTCGA TGGGATTTAT GGAGCCAAAG 2160
ATGGAGGAGC TTCCCGGCTT GCAGCTGGAC AAGCTACATA CCGGACCACC TGCCAGGACT 2220
TTCGGATCCT GGACCGGTAC CAGACTGCCT TACCAGCCAG GAAAGGATTC CGGCACCAGA 2280
CCACGAGATT TTTGTATCGT TTGGTGGGAT CAGAAGATCT GGCTGTGGAC CAAAGTATTA 2340
TCAGCCCTTA TACTTCTCGG ATCTTGAAAC CTTATATCAG GCGTGATTAT GAGACAAAGC 2400
CACCCAAACT ACAGCTCCTG TCACAGATCC GTTCCCACCT GCACAGGAGT GACCCTCACT 2460
GGACACCTGG ACCTGATGCA CCCCTCGATT ACTGCTATGT CCGACCAAAT CACATCCCAA 2520
CCATCAACTC CATGTGCCAG GAGTTTTTCT GGCCTGGCAT TGACCTGTCT GAGTGTCTGC 2580
AGTATCCAGA CTTCAGTGTT GTAGTCCTTT ATAAAAAAGT CATTGTTGCC TTTGGCTTCA 2640
TGGTTCCTGA TGTGAAGTAC AACGAAGCTT ACATCTCATT TCTGCTTGTT CATCCTGAGT 2700
GGAGGAGAGC AGGGATCGCC ACATTCATGA TCTATCATCT GATTCAGACA TGCATGGGCA 2760
AGGATGTGAC TCTTCATGTC TCGGCAAGCA ACCCCGCCAT GCTGCTGTAC CAGAAGTTTG 2820
GCTTCAAGAC CGAGGAGTAT GTTTTGGATT TTTATGATAA GTATTACCCG CTGGAGAGTA 2880
CGGAGTGTAA GCATGCATTC TTCCTGAGGC TCCGACGCTG AGGGGAGCTC TGCTCTTCCC 2940
AGCAAACGGT GGATGCTGCC AGAGAGTGGG CTTCAGAAGC CCTGCAGGCC CTTATCCTCG 3000
AAGTGGGCCC TGGTCTCCTG TGGGTAATAG CCTCCACATG GTCCAGCCGG GTGAGTGAAG 3060
CCAGTGGTAC AAGTAGGCAG TTCTGCCACC CAGAAACCAT CCAGCAGGCC CCGCGTGGCC 3120
TTCCAGCAGT ATCGTGGACT CCACTGTAGA CCAGAACCAA GTGACTCTGC CATTCTCTTC 3180
CCATACAATG AGTGAGCACA AAAGAGCCTC TAAGCTGAAG AGTTTGAGAA TGGGCCTGCT 3240
CGTCCTACGT TAGAGCTCAG GAAGTATGAA AGGTGTTAAA GATTGCGGTG CCCTCGCTGT 3300
CCCAGGACGA GAGGTTGTGA GGGATCAGGA ATGATTGCAA CCCTGTTCTC AGCCTGTGCT 3360
GTGTTGTCAT TGAACCCCAG AGGACTCACG GGGCACTGAA GTCCTTTTGT CTCTTTCTGA 3420
CTTTTGTCCC GTTCAGGAAG AATATACTCA GTGTCTGTCT CCACGCTGCT TTACCTGATC 3480
TACCTGTCAG CAGCTCCTTG CAGGGACACT GACCTGATAC AAGGAGTTTA CTCTTGGCAT 3540
GGCCTGGAAA ATAGCTTGAG AGGAACACTT GAGCTTGCCA GGCCCGTCTC GTGCTCAGGA 3600
CAGTTGCACA CAGGAGTGTC GGTGTGGAAC GGTGCAGGCA GATCTGGCTG CGCTCGCTGT 3660
CCACCTCACG AAGCTGCTTC CTGTGTTGCA CATGTGGAGT TGGACTACAG GTATATCTTA 3720
AGTGCATTCC AAAAGCATCA GATATTCTCC AATAAAAATC CTTACCTGCA ACACCTCACA 3780
GCCAGGGCTG CAGCCTAGTC A 3802
Sequence Source Ensembl
Keyword

KW-0007--Acetylation
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0539--Nucleus
KW-1185--Reference proteome
--
Interpro

IPR016181--Acyl_CoA_acyltransferase
IPR000182--GNAT_dom
PROSITE

PS51186--GNAT
Pfam

PF13673--Acetyltransf_10
Gene Ontology

GO:0005671--C:Ada2/Gcn5/Ada3 transcription activator complex
GO:0005737--C:cytoplasm
GO:0005634--C:nucleus
GO:0004402--F:histone acetyltransferase activity
GO:0000086--P:G2/M transition of mitotic cell cycle
GO:0016573--P:histone acetylation
GO:0043966--P:histone H3 acetylation
Orthology
WERAM ID Ensembl Protein ID Species Identity E-value Score
WERAM-Ran-0045 ENSRNOP00000009437.5 Rattus norvegicus 98 0.0 1481
WERAM-Ptv-0135 ENSPVAP00000011444.1 Pteropus vampyrus 94 0.0 1431
WERAM-Aim-0065 ENSAMEP00000005555.1 Ailuropoda melanoleuca 94 0.0 1422
WERAM-Chs-0142 ENSCSAP00000007739.1 Chlorocebus sabaeus 95 0.0 1421
WERAM-Paa-0133 ENSPANP00000017109.1 Papio anubis 95 0.0 1420
WERAM-Hos-0157 ENSP00000392318.2 Homo sapiens 95 0.0 1416
WERAM-Pat-0106 ENSPTRP00000022781.4 Pan troglodytes 95 0.0 1415
WERAM-Myl-0082 ENSMLUP00000006635.2 Myotis lucifugus 94 0.0 1415
WERAM-Sus-0048 ENSSSCP00000007555.2 Sus scrofa 94 0.0 1413
WERAM-Ova-0195 ENSOARP00000019685.1 Ovis aries 93 0.0 1412
WERAM-Poa-0090 ENSPPYP00000011998.2 Pongo abelii 95 0.0 1412
WERAM-Orc-0151 ENSOCUP00000013201.3 Oryctolagus cuniculus 94 0.0 1411
WERAM-Eqc-0137 ENSECAP00000015220.1 Equus caballus 94 0.0 1408
WERAM-Fec-0061 ENSFCAP00000005396.3 Felis catus 94 0.0 1405
WERAM-Caf-0065 ENSCAFP00000008130.3 Canis familiaris 94 0.0 1405
WERAM-Mup-0013 ENSMPUP00000001281.1 Mustela putorius furo 94 0.0 1401
WERAM-Dan-0066 ENSDNOP00000006490.3 Dasypus novemcinctus 92 0.0 1399
WERAM-Caj-0057 ENSCJAP00000009281.2 Callithrix jacchus 94 0.0 1394
WERAM-Nol-0102 ENSNLEP00000011864.1 Nomascus leucogenys 94 0.0 1385
WERAM-Loa-0064 ENSLAFP00000004745.2 Loxodonta africana 93 0.0 1383
WERAM-Soa-0107 ENSSARP00000010061.1 Sorex araneus 91 0.0 1364
WERAM-Otg-0028 ENSOGAP00000001707.2 Otolemur garnettii 91 0.0 1362
WERAM-Cap-0144 ENSCPOP00000011814.2 Cavia porcellus 90 0.0 1340
WERAM-Mod-0048 ENSMODP00000006860.2 Monodelphis domestica 87 0.0 1328
WERAM-Sah-0199 ENSSHAP00000021647.1 Sarcophilus harrisii 89 0.0 1318
WERAM-Tas-0003 ENSTSYP00000000350.1 Tarsius syrichta 89 0.0 1316
WERAM-Ora-0014 ENSOANP00000001992.1 Ornithorhynchus anatinus 88 0.0 1313
WERAM-Ect-0136 ENSETEP00000015380.1 Echinops telfairi 91 0.0 1289
WERAM-Tut-0188 ENSTTRP00000015573.1 Tursiops truncatus 93 0.0 1286
WERAM-Mam-0212 ENSMMUP00000030461.2 Macaca mulatta 88 0.0 1282
WERAM-Anp-0156 ENSAPLP00000016062.1 Anas platyrhynchos 86 0.0 1275
WERAM-Gaga-0091 ENSGALP00000014153.2 Gallus gallus 86 0.0 1261
WERAM-Meg-0073 ENSMGAP00000006809.2 Meleagris gallopavo 86 0.0 1260
WERAM-Fia-0096 ENSFALP00000007927.1 Ficedula albicollis 85 0.0 1239
WERAM-Tag-0086 ENSTGUP00000006066.1 Taeniopygia guttata 85 0.0 1236
WERAM-Mae-0105 ENSMEUP00000010205.1 Macropus eugenii 83 0.0 1211
WERAM-Anc-0152 ENSACAP00000013990.2 Anolis carolinensis 80 0.0 1192
WERAM-Gog-0118 ENSGGOP00000009870.2 Gorilla gorilla 90 0.0 1140
WERAM-Ere-0075 ENSEEUP00000006314.1 Erinaceus europaeus 94 0.0 1135
WERAM-Dar-0094 ENSDARP00000122559.1 Danio rerio 74 0.0 1084
WERAM-Leo-0164 ENSLOCP00000019322.1 Lepisosteus oculatus 75 0.0 1080
WERAM-Xet-0093 ENSXETP00000030216.3 Xenopus tropicalis 76 0.0 1065
WERAM-Orn-0078 ENSONIP00000008648.1 Oreochromis niloticus 70 0.0 1006
WERAM-Pof-0226 ENSPFOP00000018419.2 Poecilia formosa 69 0.0 1001
WERAM-Lac-0096 ENSLACP00000012192.1 Latimeria chalumnae 79 0.0 1000
WERAM-Tar-0140 ENSTRUP00000030432.1 Takifugu rubripes 68 0.0 977
WERAM-Gaa-0212 ENSGACP00000026301.1 Gasterosteus aculeatus 67 0.0 950
WERAM-Xim-0112 ENSXMAP00000009786.1 Xiphophorus maculatus 63 0.0 886
WERAM-Pem-0022 ENSPMAP00000003104.1 Petromyzon marinus 58 0.0 775
WERAM-Pes-0053 ENSPSIP00000007319.1 Pelodiscus sinensis 83 0.0 720
WERAM-Chh-0116 ENSCHOP00000012270.1 Choloepus hoffmanni 81 0.0 714
WERAM-Asm-0038 ENSAMXP00000004864.1 Astyanax mexicanus 62 5e-159 559
WERAM-Gam-0094 ENSGMOP00000009855.1 Gadus morhua 79 5e-145 512
WERAM-Orla-0214 ENSORLP00000025874.1 Oryzias latipes 80 3e-93 340
WERAM-Drm-0047 FBpp0080629 Drosophila melanogaster 45 2e-74 278
WERAM-Ten-0083 ENSTNIP00000009767.1 Tetraodon nigroviridis 27 2e-09 62.0
WERAM-Mim-0032 ENSMICP00000003002.1 Microcebus murinus 40 5e-08 57.4
WERAM-Dio-0090 ENSDORP00000009372.1 Dipodomys ordii 40 6e-08 57.0
WERAM-Bot-0152 ENSBTAP00000022557.4 Bos taurus 40 7e-08 57.0
WERAM-Ict-0115 ENSSTOP00000011704.2 Ictidomys tridecemlineatus 40 1e-07 56.2
WERAM-Tub-0048 ENSTBEP00000005679.1 Tupaia belangeri 34 1e-06 53.1
WERAM-Ocp-0008 ENSOPRP00000000997.1 Ochotona princeps 34 1e-06 52.8
WERAM-Prc-0088 ENSPCAP00000007973.1 Procavia capensis 34 2e-06 52.4
WERAM-Vip-0089 ENSVPAP00000008163.1 Vicugna pacos 33 6e-06 50.8
Created Date 25-Jun-2016