| Tag |
Content |
| WERAM ID |
WERAM-Drm-0001 |
| Ensembl Protein ID |
FBpp0075281 |
| Uniprot Accession |
P25439; BRM_DROME; A4V1Z7; A4V1Z8; Q9VUW5; Q9VUW6
|
| Genbank Protein ID |
NP_536745.4; NP_536746.1; NP_730088.1; NP_730089.1
|
| Protein Name |
ATP-dependent helicase brm |
| Genbank Nucleotide ID |
NM_080497.5; NM_080498.3; NM_168640.2; NM_168641.1
|
| Gene Name |
BRM;CG5942 |
| Ensembl Information |
|
| Details |
| Type |
Family |
Domain |
Substrates |
AA |
References (PMIDs) |
| Ac_Reader |
Bromodomain |
Bromodomain |
|
K |
22493065
|
|
| Status |
Reviewed |
| Classification |
| Type |
Family |
E-value |
Score |
Start |
End |
| Ac_Reader |
Bromodomain |
4.20e-17 |
62.6 |
1445 |
1513 |
|
| Organism |
Drosophila melanogaster |
| NCBI Taxa ID |
7227 |
Functional Description
(View)Functional Description
Transcriptional regulator. Acts as a coactivator, assisting one or more dedicated transcriptional activators of ANTC and BXC homeotic gene clusters. Can counteract the repressive effect of Polycomb protein. ATPase subunit of the Brahma complex, a multiprotein complex which is the equivalent of the yeast SWI/SNF complex and acts by remodeling the chromatin by catalyzing an ATP-dependent alteration in the structure of nucleosomal DNA. This complex can both serve as a transcriptional coactivator or corepressor, depending on the context. |
Transcriptional regulator. Acts as a coactivator, assisting one or more dedicated transcriptional activators of ANTC and BXC homeotic gene clusters. Can counteract the repressive effect of Polycomb protein. ATPase subunit of the Brahma complex, a multiprotein complex which is the equivalent of the yeast SWI/SNF complex and acts by remodeling the chromatin by catalyzing an ATP-dependent alteration in the structure of nucleosomal DNA. This complex can both serve as a transcriptional coactivator or corepressor, depending on the context.
|
| Domain Profile |
Ac_Reader Bromodomain
BROMO.txt 3 hevsepFrepvdpqleipdYydiikePmdLstikerleegnYsspeefvkDvrlifnNakaynenkssvq 72
+ +sepF++ + + +pdYy+iik+P+d+++i +r+e +Y +++e+ kD+ ++++Na+ yne+ s ++
FBpp0075281 1445 RTLSEPFMKLPSR-QRLPDYYEIIKRPVDIKKILQRIEDCKYADLNELEKDFMQLCQNAQIYNEEASLIY 1513
6789***887777.69************************************************998765 PP
|
Protein Sequence
(Fasta) | MASPSPANSP MPPPQAPSPM APPSQSPAPS PHSPYPHQQP GPLQGPPPPG HPGAYGHPMQ 60
HGPPGQGPPG HHMPPHHQGM IFSKGPHMGM QMPPTGPNMS PYQTHGMPPN APTQPCIVSP 120
GGPPGGPPPP ERSSQENLHA LQRAIDSMEE KGLQEDPRYS QLLAMRATSK HQHLNGNQVN 180
LLRTQITAYR LLARNKPISM QMQQALQAAQ QQPPPGPPIG PPGAPGGPPP GSQHAGQPPV 240
PPQQQQQPPP SAGTPPQCST PPASNPYGPP VPGQKMQVAP PPPHMQQGQP LPPQPPQVGG 300
PPPIQQQQPP QQQQQQSQPP PPEPHQHQLP NGGKPLSMGP SGGQPLIPSS PMQPQVRGTL 360
PGMPPGSQVP QPGGGPQRQV PPAGMPMPKP NRITTVAKPV GLDPITLLQE RENRIAARIS 420
LRMQELQRLP ATMSEDLRLQ AAIELRALRV LNFQRQLRME FVQCTRRDTT LETALNIKLY 480
KRTKRQGLRE ARATEKLEKQ QKLEAERKRR QKHLEFLAAV LQHGKDLREF HRNNKAQLAR 540
MNKAVMNHHA NAEREQKKEQ ERIEKERMRR LMAEDEEGYR KLIDQKKDKR LAFLLSQTDE 600
YISNLTQMVK QHKDDQMKKK EEEGKRLIQF KKELLMSGEY IGIDEGSIVA DMRVHVVEQC 660
TGKKLTGDDA PMLKHLHRWL NMHPGWDWID DEEDSCGSND DHKPKVEEQP TATEDATDKA 720
QATGNDEDAK DLITKAKVED DEYRTEEQTY YSIAHTIHEK VVEQASIMVN GTLKEYQIKG 780
LEWLVSLYNN NLNGILADEM GLGKTIQTIS LVTYLMDRKK VMGPYLIIVP LSTLPNWVLE 840
FEKWAPAVGV VSYKGSPQGR RLLQNQMRAT KFNVLLTTYE YVIKDKAVLA KIQWKYMIID 900
EGHRMKNHHC KLTQVLNTHY IAPYRLLLTG TPLQNKLPEL WALLNFLLPS IFKSCSTFEQ 960
WFNAPFATTG EKVELNEEET ILIIRRLHKV LRPFLLRRLK KEVEHQLPDK VEYIIKCDMS 1020
ALQRVLYKHM QSKGVLLTDG SEKGKHGKGG AKALMNTIVQ LRKLCNHPFM FQHIEEKYCD 1080
HTGGHGVVSG PDLYRVSGKF ELLDRILPKL KATNHRVLLF CQMTQCMTII EDYLGWRQFG 1140
YLRLDGTTKA EDRGELLRKF NAKGSDVFVF LLSTRAGGLG LNLQTADTVV IFDSDWNPHQ 1200
DLQAQDRAHR IGQRNEVRVL RLMTVNSVEE RILAAARYKL NMDEKVIQAG MFDQKSTGSE 1260
RQQFLQTILH QDDNEEEEEN EVPDDEMINM MIARSEEEIE IFKRMDAERK KEDEEIHPGR 1320
ERLIDESELP DWLTKDDDEV ERFHYQYDED TILGRGSRQR KEVDYTDSLT EKEWLKAIDD 1380
GAEFDEEEEE DDSKRKRRKR KNRKEESDDD SLILKRRRRQ NLDKRSKKQM HKIMSAVIKH 1440
NQDGRTLSEP FMKLPSRQRL PDYYEIIKRP VDIKKILQRI EDCKYADLNE LEKDFMQLCQ 1500
NAQIYNEEAS LIYLDSIALQ KVFVGARQRI TAAADAAAVA AGDNTGEAHG NGGSDNSDND 1560
DDDGGDDGSD DEEIATTSAA AVKMKLKLNK SLASAPATPT QSSSNVSSGA ATTSKKQTRR 1620
KRSQKKYTIS DDDDDDMD 1638Protein Fasta Sequence
>FBpp0075281|BRM;CG5942|Drosophila melanogaster
MASPSPANSPMPPPQAPSPMAPPSQSPAPSPHSPYPHQQPGPLQGPPPPGHPGAYGHPMQHGPPGQGPPGHHMPPHHQGMIFSKGPHMGMQMPPTGPNMSPYQTHGMPPNAPTQPCIVSPGGPPGGPPPPERSSQENLHALQRAIDSMEEKGLQEDPRYSQLLAMRATSKHQHLNGNQVNLLRTQITAYRLLARNKPISMQMQQALQAAQQQPPPGPPIGPPGAPGGPPPGSQHAGQPPVPPQQQQQPPPSAGTPPQCSTPPASNPYGPPVPGQKMQVAPPPPHMQQGQPLPPQPPQVGGPPPIQQQQPPQQQQQQSQPPPPEPHQHQLPNGGKPLSMGPSGGQPLIPSSPMQPQVRGTLPGMPPGSQVPQPGGGPQRQVPPAGMPMPKPNRITTVAKPVGLDPITLLQERENRIAARISLRMQELQRLPATMSEDLRLQAAIELRALRVLNFQRQLRMEFVQCTRRDTTLETALNIKLYKRTKRQGLREARATEKLEKQQKLEAERKRRQKHLEFLAAVLQHGKDLREFHRNNKAQLARMNKAVMNHHANAEREQKKEQERIEKERMRRLMAEDEEGYRKLIDQKKDKRLAFLLSQTDEYISNLTQMVKQHKDDQMKKKEEEGKRLIQFKKELLMSGEYIGIDEGSIVADMRVHVVEQCTGKKLTGDDAPMLKHLHRWLNMHPGWDWIDDEEDSCGSNDDHKPKVEEQPTATEDATDKAQATGNDEDAKDLITKAKVEDDEYRTEEQTYYSIAHTIHEKVVEQASIMVNGTLKEYQIKGLEWLVSLYNNNLNGILADEMGLGKTIQTISLVTYLMDRKKVMGPYLIIVPLSTLPNWVLEFEKWAPAVGVVSYKGSPQGRRLLQNQMRATKFNVLLTTYEYVIKDKAVLAKIQWKYMIIDEGHRMKNHHCKLTQVLNTHYIAPYRLLLTGTPLQNKLPELWALLNFLLPSIFKSCSTFEQWFNAPFATTGEKVELNEEETILIIRRLHKVLRPFLLRRLKKEVEHQLPDKVEYIIKCDMSALQRVLYKHMQSKGVLLTDGSEKGKHGKGGAKALMNTIVQLRKLCNHPFMFQHIEEKYCDHTGGHGVVSGPDLYRVSGKFELLDRILPKLKATNHRVLLFCQMTQCMTIIEDYLGWRQFGYLRLDGTTKAEDRGELLRKFNAKGSDVFVFLLSTRAGGLGLNLQTADTVVIFDSDWNPHQDLQAQDRAHRIGQRNEVRVLRLMTVNSVEERILAAARYKLNMDEKVIQAGMFDQKSTGSERQQFLQTILHQDDNEEEEENEVPDDEMINMMIARSEEEIEIFKRMDAERKKEDEEIHPGRERLIDESELPDWLTKDDDEVERFHYQYDEDTILGRGSRQRKEVDYTDSLTEKEWLKAIDDGAEFDEEEEEDDSKRKRRKRKNRKEESDDDSLILKRRRRQNLDKRSKKQMHKIMSAVIKHNQDGRTLSEPFMKLPSRQRLPDYYEIIKRPVDIKKILQRIEDCKYADLNELEKDFMQLCQNAQIYNEEASLIYLDSIALQKVFVGARQRITAAADAAAVAAGDNTGEAHGNGGSDNSDNDDDDGGDDGSDDEEIATTSAAAVKMKLKLNKSLASAPATPTQSSSNVSSGAATTSKKQTRRKRSQKKYTISDDDDDDMD |
Nucleotide Sequence
(Fasta) | TCGCGTTGTG AAAAGAGAAG AAAACCTTCT GAAAACAGTG CTAATAGGTA ATACTTTCGG 60
TGCCAAATGG AGCAATCCGA TTGCGTTCTT CGCGTGCGAT TAGCGTGCAG TTGATTTCGG 120
CCGATTTGGC GTATCTTTAG CCGTTATTTT GGGTTTGCAC CGGGCTGCGC GAAAAAGTGT 180
GCCAAAAGAG GCACACAAAA CGGTAGCTAC GATTACATAT CGTGGCTATA GCTTCTTTAA 240
TGTTGGTAAA TACAGTGCAT TGACGTGTGT TCCATCTGCA GATTAGGCTG CACCAGTTGC 300
TGGATATCGC TATTGGATAA AGTCAAGAAA GGAGCTGCAA TATGGCCTCG CCCTCTCCGG 360
CGAACAGTCC CATGCCACCG CCACAGGCGC CCAGTCCGAT GGCCCCGCCC TCGCAGAGTC 420
CCGCCCCCTC GCCGCACAGC CCGTATCCGC ACCAGCAGCC GGGTCCACTG CAAGGACCTC 480
CGCCACCCGG ACATCCCGGT GCCTACGGAC ATCCCATGCA GCACGGACCA CCCGGCCAGG 540
GTCCACCCGG GCATCATATG CCACCGCACC ACCAGGGGAT GATTTTCTCA AAAGGTCCGC 600
ACATGGGAAT GCAGATGCCG CCGACGGGAC CGAACATGTC CCCCTACCAA ACCCACGGAA 660
TGCCACCCAA TGCACCCACA CAACCCTGCA TAGTGTCACC TGGTGGCCCA CCTGGAGGCC 720
CGCCACCTCC GGAGCGCTCG AGCCAGGAGA ACCTGCACGC GCTTCAACGC GCCATTGATT 780
CAATGGAGGA AAAGGGCTTG CAAGAGGATC CTCGCTACTC GCAGCTGCTG GCAATGCGAG 840
CAACCTCGAA GCATCAGCAC CTTAATGGCA ATCAGGTTAA CTTGTTGCGC ACACAGATCA 900
CCGCCTATCG GTTGCTGGCG CGGAACAAGC CCATATCCAT GCAGATGCAG CAGGCGTTGC 960
AGGCCGCACA GCAACAGCCA CCGCCAGGAC CTCCAATTGG GCCACCTGGA GCACCAGGCG 1020
GACCGCCACC AGGGAGCCAG CATGCAGGAC AACCGCCCGT GCCGCCGCAA CAACAGCAAC 1080
AACCGCCACC TTCAGCAGGA ACTCCACCCC AGTGCTCCAC GCCGCCCGCA AGCAATCCTT 1140
ATGGACCGCC AGTTCCTGGC CAGAAAATGC AGGTAGCGCC ACCACCGCCA CACATGCAAC 1200
AGGGACAGCC ATTGCCACCA CAACCGCCAC AAGTGGGTGG ACCCCCGCCT ATACAACAGC 1260
AGCAACCACC TCAGCAGCAG CAACAACAGT CGCAGCCCCC GCCACCGGAG CCACATCAGC 1320
ACCAGTTGCC AAACGGAGGC AAACCCCTGA GTATGGGGCC ATCTGGCGGG CAACCACTAA 1380
TACCTTCATC ACCCATGCAG CCACAAGTGA GAGGGACACT GCCAGGAATG CCGCCAGGTA 1440
GTCAGGTTCC GCAACCAGGA GGAGGTCCTC AGCGACAGGT ACCACCTGCG GGCATGCCGA 1500
TGCCCAAGCC CAATCGCATT ACAACGGTGG CCAAACCCGT CGGTCTGGAT CCCATAACAT 1560
TGCTGCAGGA AAGGGAGAAT AGGATAGCAG CCAGGATATC ATTGCGCATG CAGGAGTTGC 1620
AGCGACTGCC GGCCACGATG TCCGAGGATC TGCGTCTGCA AGCGGCTATC GAGTTGAGGG 1680
CCCTAAGGGT CTTGAACTTC CAGCGACAGC TGCGTATGGA GTTTGTTCAG TGCACGAGAC 1740
GAGATACCAC TTTGGAAACA GCGTTAAACA TTAAGCTCTA CAAGAGGACC AAGAGGCAGG 1800
GCCTGCGGGA GGCACGTGCC ACCGAGAAGC TAGAGAAGCA ACAGAAGCTA GAGGCTGAAC 1860
GAAAGCGTCG CCAAAAGCAT CTGGAGTTCT TGGCTGCTGT GCTTCAGCAC GGCAAGGATC 1920
TAAGGGAGTT CCACAGAAAT AATAAGGCCC AGCTTGCAAG GATGAACAAG GCCGTGATGA 1980
ATCACCACGC CAATGCCGAG CGTGAACAGA AGAAGGAACA AGAGCGCATC GAAAAGGAAC 2040
GTATGCGACG TCTGATGGCC GAGGATGAGG AGGGTTACCG CAAGCTGATT GATCAAAAGA 2100
AGGACAAGAG ATTGGCTTTC CTACTGTCGC AGACAGATGA GTATATTAGC AACCTAACTC 2160
AGATGGTGAA ACAGCACAAG GACGACCAGA TGAAGAAAAA GGAGGAGGAG GGCAAGCGGC 2220
TGATACAGTT CAAAAAGGAG CTGCTGATGA GCGGAGAGTA CATTGGCATT GATGAGGGCA 2280
GCATTGTTGC CGATATGCGG GTACATGTGG TGGAACAGTG CACGGGTAAG AAACTCACCG 2340
GCGATGATGC ACCCATGCTG AAGCACTTGC ACCGCTGGCT GAATATGCAT CCTGGCTGGG 2400
ATTGGATCGA CGACGAGGAG GACAGCTGTG GGAGCAACGA CGATCATAAA CCCAAGGTGG 2460
AGGAGCAACC AACGGCAACA GAAGATGCCA CCGACAAAGC GCAGGCGACG GGCAACGATG 2520
AGGATGCCAA GGATCTAATT ACCAAGGCCA AGGTGGAGGA CGATGAGTAC AGGACGGAGG 2580
AACAGACGTA CTACAGCATC GCTCATACCA TTCATGAAAA GGTTGTGGAG CAGGCCAGCA 2640
TCATGGTTAA TGGTACGCTC AAGGAATACC AGATCAAAGG CTTGGAGTGG TTGGTTTCGC 2700
TGTACAATAA CAATCTAAAT GGTATTTTGG CCGATGAAAT GGGTTTGGGT AAAACCATTC 2760
AAACCATTTC GCTGGTAACC TACCTTATGG ATCGAAAGAA GGTTATGGGT CCTTACTTGA 2820
TTATTGTACC ACTCTCCACC CTGCCCAATT GGGTGCTGGA ATTCGAGAAG TGGGCGCCAG 2880
CCGTGGGTGT AGTCAGCTAC AAGGGCAGTC CGCAGGGAAG GCGATTGCTG CAAAATCAAA 2940
TGAGAGCAAC CAAGTTCAAT GTGCTGTTAA CCACATATGA GTACGTGATT AAGGACAAGG 3000
CGGTGCTGGC CAAGATCCAG TGGAAATACA TGATTATCGA CGAGGGTCAC CGCATGAAGA 3060
ACCATCACTG CAAACTCACC CAGGTGCTGA ACACCCACTA CATTGCCCCC TATCGGTTAC 3120
TTCTCACGGG TACACCTCTG CAAAACAAGC TTCCCGAGTT GTGGGCGCTA CTTAATTTCC 3180
TGCTGCCCTC GATCTTTAAG TCCTGCTCCA CATTTGAACA GTGGTTCAAT GCGCCATTTG 3240
CCACCACTGG CGAGAAGGTC GAGCTAAACG AGGAGGAGAC CATCCTTATC ATTCGTCGTC 3300
TGCACAAGGT TCTTCGTCCT TTCCTGTTGC GTCGCCTCAA AAAGGAGGTA GAGCACCAGC 3360
TGCCCGACAA GGTCGAGTAC ATCATCAAGT GCGACATGTC CGCGCTGCAA CGCGTTCTCT 3420
ACAAGCACAT GCAGAGCAAG GGTGTCCTGC TCACCGATGG TTCCGAGAAG GGCAAGCACG 3480
GCAAGGGAGG CGCTAAGGCG CTGATGAACA CGATCGTACA GCTGCGCAAG CTGTGCAACC 3540
ATCCGTTTAT GTTCCAGCAC ATAGAAGAGA AGTACTGCGA TCACACTGGC GGCCACGGAG 3600
TTGTATCCGG ACCGGATCTG TATCGTGTCT CTGGCAAATT CGAGCTGCTT GATCGCATCC 3660
TGCCCAAGCT GAAGGCGACC AATCATCGCG TGCTGCTCTT CTGTCAGATG ACCCAATGCA 3720
TGACCATCAT CGAAGACTAC CTGGGATGGC GCCAATTCGG CTACCTTCGA CTCGACGGTA 3780
CCACGAAGGC CGAGGATCGT GGCGAACTAC TGCGAAAATT CAACGCCAAA GGCTCGGATG 3840
TATTTGTCTT TTTGCTATCT ACCCGAGCTG GTGGTTTGGG TCTTAATCTG CAGACCGCCG 3900
ATACTGTAGT AATCTTCGAC TCCGATTGGA ATCCCCATCA GGATCTGCAA GCCCAGGATC 3960
GTGCCCATCG TATTGGTCAA CGTAACGAGG TGCGCGTCCT GCGACTAATG ACAGTCAACT 4020
CGGTGGAAGA GCGCATCTTG GCAGCAGCCA GGTACAAGCT GAACATGGAC GAGAAGGTCA 4080
TCCAGGCTGG TATGTTCGAT CAGAAGTCAA CGGGTAGCGA GCGACAGCAG TTCCTACAAA 4140
CGATTCTGCA CCAGGATGAC AACGAAGAGG AGGAGGAAAA TGAGGTGCCC GATGACGAAA 4200
TGATCAACAT GATGATCGCC CGCAGCGAGG AGGAGATTGA AATATTTAAG CGCATGGATG 4260
CTGAGCGCAA GAAGGAGGAT GAGGAGATCC ATCCGGGTAG GGAACGTCTG ATCGATGAGT 4320
CCGAGCTACC CGACTGGTTG ACAAAGGATG ATGACGAAGT AGAGCGTTTC CACTATCAGT 4380
ACGACGAGGA TACCATTCTA GGTCGAGGCT CCCGGCAGCG AAAGGAAGTA GACTACACCG 4440
ATAGTTTGAC TGAAAAGGAG TGGCTGAAAG CCATCGACGA TGGCGCTGAG TTCGACGAGG 4500
AAGAGGAGGA AGACGATTCG AAGCGCAAGC GACGAAAGCG TAAGAATCGG AAGGAAGAGT 4560
CCGACGATGA TTCGTTGATC CTAAAACGGC GACGACGCCA AAATCTGGAC AAGCGGTCCA 4620
AGAAGCAGAT GCACAAGATT ATGAGTGCGG TTATCAAGCA CAACCAAGAT GGACGAACCC 4680
TGTCCGAACC GTTCATGAAG TTGCCTTCGC GGCAGAGGTT GCCCGACTAC TACGAGATCA 4740
TTAAGCGGCC AGTTGATATT AAGAAAATCC TGCAGCGCAT TGAGGACTGC AAGTATGCCG 4800
ATCTCAACGA GCTGGAGAAG GACTTTATGC AGCTATGCCA GAATGCACAG ATCTACAACG 4860
AAGAGGCGTC TCTGATTTAC CTGGACTCGA TTGCCCTGCA AAAGGTATTC GTTGGGGCCA 4920
GGCAGAGGAT AACAGCTGCA GCGGATGCAG CCGCAGTGGC AGCCGGAGAT AACACGGGTG 4980
AAGCGCACGG CAATGGAGGT TCGGATAATT CGGACAACGA CGACGACGAT GGTGGCGATG 5040
ACGGCTCCGA CGACGAGGAG ATTGCAACCA CTTCAGCGGC GGCTGTCAAA ATGAAGCTGA 5100
AACTGAACAA ATCTCTGGCT AGTGCGCCCG CTACGCCCAC GCAATCATCG TCGAATGTGA 5160
GCAGCGGAGC GGCTACCACA TCCAAGAAGC AGACGCGTCG CAAGCGCTCC CAAAAGAAGT 5220
ACACTATTTC AGACGATGAC GACGATGACA TGGACTAGCT ACCGTTGGGA GTGATCTTCA 5280
AGCGCGGATC GTCGGATGTC GAAGGCATGG GCAATTGATT ATTAATTAGT TTAAGTTTTA 5340
CTTTCAAGGA CGATGCTTAC CAAAACCCTA GCCTACGGGT TTTTTTAACC ATCTAACCTA 5400
TCATGCTATC ACTTTTATCT ATACTAATTT TCTAGTTGTA GGTTCTCGAT TAAGTTTCCT 5460
ATTCAATTAT TTTCGCACAC ACCATTTATT TCTCCCAATT CTATTGATTG TATAATTATG 5520
TGCTTTAAAA TAAATGCATA CCTAACATAA AGT
5554Nucleotide Fasta Sequence
>FBpp0075281|Bromodomain|Drosophila melanogaster
TCGCGTTGTGAAAAGAGAAGAAAACCTTCTGAAAACAGTGCTAATAGGTAATACTTTCGGTGCCAAATGGAGCAATCCGATTGCGTTCTTCGCGTGCGATTAGCGTGCAGTTGATTTCGGCCGATTTGGCGTATCTTTAGCCGTTATTTTGGGTTTGCACCGGGCTGCGCGAAAAAGTGTGCCAAAAGAGGCACACAAAACGGTAGCTACGATTACATATCGTGGCTATAGCTTCTTTAATGTTGGTAAATACAGTGCATTGACGTGTGTTCCATCTGCAGATTAGGCTGCACCAGTTGCTGGATATCGCTATTGGATAAAGTCAAGAAAGGAGCTGCAATATGGCCTCGCCCTCTCCGGCGAACAGTCCCATGCCACCGCCACAGGCGCCCAGTCCGATGGCCCCGCCCTCGCAGAGTCCCGCCCCCTCGCCGCACAGCCCGTATCCGCACCAGCAGCCGGGTCCACTGCAAGGACCTCCGCCACCCGGACATCCCGGTGCCTACGGACATCCCATGCAGCACGGACCACCCGGCCAGGGTCCACCCGGGCATCATATGCCACCGCACCACCAGGGGATGATTTTCTCAAAAGGTCCGCACATGGGAATGCAGATGCCGCCGACGGGACCGAACATGTCCCCCTACCAAACCCACGGAATGCCACCCAATGCACCCACACAACCCTGCATAGTGTCACCTGGTGGCCCACCTGGAGGCCCGCCACCTCCGGAGCGCTCGAGCCAGGAGAACCTGCACGCGCTTCAACGCGCCATTGATTCAATGGAGGAAAAGGGCTTGCAAGAGGATCCTCGCTACTCGCAGCTGCTGGCAATGCGAGCAACCTCGAAGCATCAGCACCTTAATGGCAATCAGGTTAACTTGTTGCGCACACAGATCACCGCCTATCGGTTGCTGGCGCGGAACAAGCCCATATCCATGCAGATGCAGCAGGCGTTGCAGGCCGCACAGCAACAGCCACCGCCAGGACCTCCAATTGGGCCACCTGGAGCACCAGGCGGACCGCCACCAGGGAGCCAGCATGCAGGACAACCGCCCGTGCCGCCGCAACAACAGCAACAACCGCCACCTTCAGCAGGAACTCCACCCCAGTGCTCCACGCCGCCCGCAAGCAATCCTTATGGACCGCCAGTTCCTGGCCAGAAAATGCAGGTAGCGCCACCACCGCCACACATGCAACAGGGACAGCCATTGCCACCACAACCGCCACAAGTGGGTGGACCCCCGCCTATACAACAGCAGCAACCACCTCAGCAGCAGCAACAACAGTCGCAGCCCCCGCCACCGGAGCCACATCAGCACCAGTTGCCAAACGGAGGCAAACCCCTGAGTATGGGGCCATCTGGCGGGCAACCACTAATACCTTCATCACCCATGCAGCCACAAGTGAGAGGGACACTGCCAGGAATGCCGCCAGGTAGTCAGGTTCCGCAACCAGGAGGAGGTCCTCAGCGACAGGTACCACCTGCGGGCATGCCGATGCCCAAGCCCAATCGCATTACAACGGTGGCCAAACCCGTCGGTCTGGATCCCATAACATTGCTGCAGGAAAGGGAGAATAGGATAGCAGCCAGGATATCATTGCGCATGCAGGAGTTGCAGCGACTGCCGGCCACGATGTCCGAGGATCTGCGTCTGCAAGCGGCTATCGAGTTGAGGGCCCTAAGGGTCTTGAACTTCCAGCGACAGCTGCGTATGGAGTTTGTTCAGTGCACGAGACGAGATACCACTTTGGAAACAGCGTTAAACATTAAGCTCTACAAGAGGACCAAGAGGCAGGGCCTGCGGGAGGCACGTGCCACCGAGAAGCTAGAGAAGCAACAGAAGCTAGAGGCTGAACGAAAGCGTCGCCAAAAGCATCTGGAGTTCTTGGCTGCTGTGCTTCAGCACGGCAAGGATCTAAGGGAGTTCCACAGAAATAATAAGGCCCAGCTTGCAAGGATGAACAAGGCCGTGATGAATCACCACGCCAATGCCGAGCGTGAACAGAAGAAGGAACAAGAGCGCATCGAAAAGGAACGTATGCGACGTCTGATGGCCGAGGATGAGGAGGGTTACCGCAAGCTGATTGATCAAAAGAAGGACAAGAGATTGGCTTTCCTACTGTCGCAGACAGATGAGTATATTAGCAACCTAACTCAGATGGTGAAACAGCACAAGGACGACCAGATGAAGAAAAAGGAGGAGGAGGGCAAGCGGCTGATACAGTTCAAAAAGGAGCTGCTGATGAGCGGAGAGTACATTGGCATTGATGAGGGCAGCATTGTTGCCGATATGCGGGTACATGTGGTGGAACAGTGCACGGGTAAGAAACTCACCGGCGATGATGCACCCATGCTGAAGCACTTGCACCGCTGGCTGAATATGCATCCTGGCTGGGATTGGATCGACGACGAGGAGGACAGCTGTGGGAGCAACGACGATCATAAACCCAAGGTGGAGGAGCAACCAACGGCAACAGAAGATGCCACCGACAAAGCGCAGGCGACGGGCAACGATGAGGATGCCAAGGATCTAATTACCAAGGCCAAGGTGGAGGACGATGAGTACAGGACGGAGGAACAGACGTACTACAGCATCGCTCATACCATTCATGAAAAGGTTGTGGAGCAGGCCAGCATCATGGTTAATGGTACGCTCAAGGAATACCAGATCAAAGGCTTGGAGTGGTTGGTTTCGCTGTACAATAACAATCTAAATGGTATTTTGGCCGATGAAATGGGTTTGGGTAAAACCATTCAAACCATTTCGCTGGTAACCTACCTTATGGATCGAAAGAAGGTTATGGGTCCTTACTTGATTATTGTACCACTCTCCACCCTGCCCAATTGGGTGCTGGAATTCGAGAAGTGGGCGCCAGCCGTGGGTGTAGTCAGCTACAAGGGCAGTCCGCAGGGAAGGCGATTGCTGCAAAATCAAATGAGAGCAACCAAGTTCAATGTGCTGTTAACCACATATGAGTACGTGATTAAGGACAAGGCGGTGCTGGCCAAGATCCAGTGGAAATACATGATTATCGACGAGGGTCACCGCATGAAGAACCATCACTGCAAACTCACCCAGGTGCTGAACACCCACTACATTGCCCCCTATCGGTTACTTCTCACGGGTACACCTCTGCAAAACAAGCTTCCCGAGTTGTGGGCGCTACTTAATTTCCTGCTGCCCTCGATCTTTAAGTCCTGCTCCACATTTGAACAGTGGTTCAATGCGCCATTTGCCACCACTGGCGAGAAGGTCGAGCTAAACGAGGAGGAGACCATCCTTATCATTCGTCGTCTGCACAAGGTTCTTCGTCCTTTCCTGTTGCGTCGCCTCAAAAAGGAGGTAGAGCACCAGCTGCCCGACAAGGTCGAGTACATCATCAAGTGCGACATGTCCGCGCTGCAACGCGTTCTCTACAAGCACATGCAGAGCAAGGGTGTCCTGCTCACCGATGGTTCCGAGAAGGGCAAGCACGGCAAGGGAGGCGCTAAGGCGCTGATGAACACGATCGTACAGCTGCGCAAGCTGTGCAACCATCCGTTTATGTTCCAGCACATAGAAGAGAAGTACTGCGATCACACTGGCGGCCACGGAGTTGTATCCGGACCGGATCTGTATCGTGTCTCTGGCAAATTCGAGCTGCTTGATCGCATCCTGCCCAAGCTGAAGGCGACCAATCATCGCGTGCTGCTCTTCTGTCAGATGACCCAATGCATGACCATCATCGAAGACTACCTGGGATGGCGCCAATTCGGCTACCTTCGACTCGACGGTACCACGAAGGCCGAGGATCGTGGCGAACTACTGCGAAAATTCAACGCCAAAGGCTCGGATGTATTTGTCTTTTTGCTATCTACCCGAGCTGGTGGTTTGGGTCTTAATCTGCAGACCGCCGATACTGTAGTAATCTTCGACTCCGATTGGAATCCCCATCAGGATCTGCAAGCCCAGGATCGTGCCCATCGTATTGGTCAACGTAACGAGGTGCGCGTCCTGCGACTAATGACAGTCAACTCGGTGGAAGAGCGCATCTTGGCAGCAGCCAGGTACAAGCTGAACATGGACGAGAAGGTCATCCAGGCTGGTATGTTCGATCAGAAGTCAACGGGTAGCGAGCGACAGCAGTTCCTACAAACGATTCTGCACCAGGATGACAACGAAGAGGAGGAGGAAAATGAGGTGCCCGATGACGAAATGATCAACATGATGATCGCCCGCAGCGAGGAGGAGATTGAAATATTTAAGCGCATGGATGCTGAGCGCAAGAAGGAGGATGAGGAGATCCATCCGGGTAGGGAACGTCTGATCGATGAGTCCGAGCTACCCGACTGGTTGACAAAGGATGATGACGAAGTAGAGCGTTTCCACTATCAGTACGACGAGGATACCATTCTAGGTCGAGGCTCCCGGCAGCGAAAGGAAGTAGACTACACCGATAGTTTGACTGAAAAGGAGTGGCTGAAAGCCATCGACGATGGCGCTGAGTTCGACGAGGAAGAGGAGGAAGACGATTCGAAGCGCAAGCGACGAAAGCGTAAGAATCGGAAGGAAGAGTCCGACGATGATTCGTTGATCCTAAAACGGCGACGACGCCAAAATCTGGACAAGCGGTCCAAGAAGCAGATGCACAAGATTATGAGTGCGGTTATCAAGCACAACCAAGATGGACGAACCCTGTCCGAACCGTTCATGAAGTTGCCTTCGCGGCAGAGGTTGCCCGACTACTACGAGATCATTAAGCGGCCAGTTGATATTAAGAAAATCCTGCAGCGCATTGAGGACTGCAAGTATGCCGATCTCAACGAGCTGGAGAAGGACTTTATGCAGCTATGCCAGAATGCACAGATCTACAACGAAGAGGCGTCTCTGATTTACCTGGACTCGATTGCCCTGCAAAAGGTATTCGTTGGGGCCAGGCAGAGGATAACAGCTGCAGCGGATGCAGCCGCAGTGGCAGCCGGAGATAACACGGGTGAAGCGCACGGCAATGGAGGTTCGGATAATTCGGACAACGACGACGACGATGGTGGCGATGACGGCTCCGACGACGAGGAGATTGCAACCACTTCAGCGGCGGCTGTCAAAATGAAGCTGAAACTGAACAAATCTCTGGCTAGTGCGCCCGCTACGCCCACGCAATCATCGTCGAATGTGAGCAGCGGAGCGGCTACCACATCCAAGAAGCAGACGCGTCGCAAGCGCTCCCAAAAGAAGTACACTATTTCAGACGATGACGACGATGACATGGACTAGCTACCGTTGGGAGTGATCTTCAAGCGCGGATCGTCGGATGTCGAAGGCATGGGCAATTGATTATTAATTAGTTTAAGTTTTACTTTCAAGGACGATGCTTACCAAAACCCTAGCCTACGGGTTTTTTTAACCATCTAACCTATCATGCTATCACTTTTATCTATACTAATTTTCTAGTTGTAGGTTCTCGATTAAGTTTCCTATTCAATTATTTTCGCACACACCATTTATTTCTCCCAATTCTATTGATTGTATAATTATGTGCTTTAAAATAAATGCATACCTAACATAAAGT
|
| Sequence Source |
Ensembl |
| Keyword |
KW-0010--Activator
KW-0025--Alternative splicing
KW-0067--ATP-binding
KW-0103--Bromodomain
KW-0156--Chromatin regulator
KW-0181--Complete proteome
KW-0217--Developmental protein
KW-0347--Helicase
KW-0378--Hydrolase
KW-0547--Nucleotide-binding
KW-0539--Nucleus
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0804--Transcription
KW-0805--Transcription regulation
--
|
| Interpro |
IPR006576--BRK_domain
IPR001487--Bromodomain
IPR018359--Bromodomain_CS
IPR014978--Gln-Leu-Gln_QLQ
IPR014001--Helicase_ATP-bd
IPR001650--Helicase_C
IPR014012--HSA_dom
IPR027417--P-loop_NTPase
IPR029295--SnAC
IPR000330--SNF2_N
|
| PROSITE |
PS00633--BROMODOMAIN_1
PS50014--BROMODOMAIN_2
PS51192--HELICASE_ATP_BIND_1
PS51194--HELICASE_CTER
PS51204--HSA
PS51666--QLQ
|
| Pfam |
PF07533--BRK
PF00439--Bromodomain
PF00271--Helicase_C
PF07529--HSA
PF08880--QLQ
PF14619--SnAC
PF00176--SNF2_N
|
| Gene Ontology |
GO:0035060--C:brahma complex
GO:0005634--C:nucleus
GO:0070604--C:PBAF complex
GO:0005524--F:ATP binding
GO:0016887--F:ATPase activity
GO:0004386--F:helicase activity
GO:0003713--F:transcription coactivator activity
GO:0043044--P:ATP-dependent chromatin remodeling
GO:0007409--P:axonogenesis
GO:0048096--P:chromatin-mediated maintenance of transcription
GO:0070983--P:dendrite guidance
GO:0048813--P:dendrite morphogenesis
GO:0035172--P:hemocyte proliferation
GO:0035329--P:hippo signaling
GO:0043974--P:histone H3-K27 acetylation
GO:0007480--P:imaginal disc-derived leg morphogenesis
GO:0008587--P:imaginal disc-derived wing margin morphogenesis
GO:0008586--P:imaginal disc-derived wing vein morphogenesis
GO:0007474--P:imaginal disc-derived wing vein specification
GO:0036335--P:intestinal stem cell homeostasis
GO:0007517--P:muscle organ development
GO:2000134--P:negative regulation of G1/S transition of mitotic cell cycle
GO:0007406--P:negative regulation of neuroblast proliferation
GO:0022008--P:neurogenesis
GO:0048666--P:neuron development
GO:0048477--P:oogenesis
GO:0006909--P:phagocytosis
GO:0045742--P:positive regulation of epidermal growth factor receptor signaling pathway
GO:2000648--P:positive regulation of stem cell proliferation
GO:0045893--P:positive regulation of transcription, DNA-templated
GO:0045088--P:regulation of innate immune response
GO:0006357--P:regulation of transcription from RNA polymerase II promoter
GO:0006351--P:transcription, DNA-templated
GO:0007419--P:ventral cord development
|
| Orthology |
|
| Created Date |
25-Jun-2016 |
