Tag |
Content |
WERAM ID |
WERAM-Mum-0069 |
Ensembl Protein ID |
ENSMUSP00000108203.1 |
Uniprot Accession |
P41230; KDM5C_MOUSE; O54995; Q3TYU8; Q3U1X6; Q3U282; Q6ZQF8; Q80XQ9; Q9CVI4; Q9D0C3; Q9QVR8; Q9R039 |
Genbank Protein ID |
NP_038696.2; XP_006528832.1; XP_006528835.1 |
Protein Name |
Lysine-specific demethylase 5C |
Genbank Nucleotide ID |
NM_013668.4; XM_006528769.2; XM_006528772.2 |
Gene Name |
KDM5C;JARID1C;SMCX |
Ensembl Information |
|
Details |
Type |
Family |
Domain |
Substrates |
AA |
References (PMIDs) |
HDM |
JARID |
Jmjc |
H3K9me3 |
K |
26551685 |
Me_Reader |
PHD |
PHD1 |
H3K9me3 |
K |
26551685 |
|
Status |
Reviewed |
Classification |
Type |
Family |
E-value |
Score |
Start |
End |
HDM |
JARID |
3.70e-103 |
344 |
468 |
634 |
Me_Reader |
PHD |
7.50e-20 |
72.3 |
326 |
1249 |
|
Organism |
Mus musculus |
NCBI Taxa ID |
10090 |
Functional Description (View)Functional Description
Histone demethylase that specifically demethylates 'Lys-4' of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-9', H3 'Lys-27', H3 'Lys-36', H3 'Lys-79' or H4 'Lys-20'. Demethylates trimethylated and dimethylated but not monomethylated H3 'Lys-4'. Participates in transcriptional repression of neuronal genes by recruiting histone deacetylases and REST at neuron-restrictive silencer elements (By similarity). Represses the CLOCK-ARNTL/BMAL1 heterodimer-mediated transcriptional activation of the core clock component PER2. |
Histone demethylase that specifically demethylates 'Lys-4' of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-9', H3 'Lys-27', H3 'Lys-36', H3 'Lys-79' or H4 'Lys-20'. Demethylates trimethylated and dimethylated but not monomethylated H3 'Lys-4'. Participates in transcriptional repression of neuronal genes by recruiting histone deacetylases and REST at neuron-restrictive silencer elements (By similarity). Represses the CLOCK-ARNTL/BMAL1 heterodimer-mediated transcriptional activation of the core clock component PER2.
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Domain Profile |
HDM JARID
JARID.txt 1 eyaesgwnlnnlpvleesvlahinadisgvkvpwlyvgmcfsafcwhvedhwsysinylhfgepkvwygvpgsaaekleevlkklapel 89 eya+sgwnln++pvle+svl+hinadisg+kvpwlyvgm+fsafcwh+edhwsysinylh+gepk+wygvp+ aae+leev+kkl+pel ENSMUSP00000108203.1 468 EYATSGWNLNVMPVLEQSVLCHINADISGMKVPWLYVGMVFSAFCWHIEDHWSYSINYLHWGEPKTWYGVPSLAAEHLEEVMKKLTPEL 556 7**************************************************************************************** PP JARID.txt 90 fesqpdllhqlvtllnpnilkeegvpvyrtnqkagefvitfprayhsgfnqgfnfaeavnfatvdwlaagreavesys 167 f+sqpdllhqlvtl+npn+l+++gvpv+rtnq+agefvitfprayhsgfnqg+nfaeavnf+t+dwl+agr+++e+y+ ENSMUSP00000108203.1 557 FDSQPDLLHQLVTLMNPNTLMSHGVPVVRTNQCAGEFVITFPRAYHSGFNQGYNFAEAVNFCTADWLPAGRQCIEHYR 634 *****************************************************************************7 PP
Me_Reader PHD
PHD.txt 3 iClvCgkddegekemvqCdeCddwfHlkCvklplsslpegkswyCpsCk 51 +C++C++ de++k ++ Cd+Cdd +H+ C+ +pl ++p+g w+Cp+C+ ENSMUSP00000108203.1 326 VCRMCSRGDEDDK-LLLCDGCDDNYHIFCLLPPLPEIPKG-VWRCPKCV 372 8****77777776.**************************.*******7 PP PHD.txt 3 iClvCgkddegekemvqCdeCddwfHlkCvklp......lsslpeg.........kswyCpsCke 52 iC+ Cg++ +g ++qCd C+dwfH++Cv++p +sslp++ ++++Cp C++ ENSMUSP00000108203.1 1187 ICV-CGQVPAGVG-ALQCDLCQDWFHGRCVTVPrllssqRSSLPSSpllawwewdTKFLCPLCMR 1249 8*9.*99999976.*******************87655555555449988877777788****97 PP
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Protein Sequence (Fasta) | MELGSDDFLP PPECPVFEPS WAEFRDPLGY IAKIRPIAEK SGICKIRPPA DWQPPFAVEV 60 DNFRFTPRIQ RLNELEAQTR VKLNYLDQIA KFWEIQGSSL KIPNVERRIL DLYSLSKIVV 120 EEGGYETICK DRRWARVAQR LNYPPGKNIG SLLRSHYERI VYPYEMYQSG ANLVQCNTRP 180 FDNEEKDKEY KPHSIPLRQS VQPSKFNSYG RRAKRLQPDP EPTEEDIEKN PELKKLQIYG 240 AGPKMMGLGL MAKDKTLRKK DKEGPECPPT VVVKEELGGD VKMESTSPKT FLEGKEELSH 300 SPEPCTKMTM RLRRNHSNAQ FIESYVCRMC SRGDEDDKLL LCDGCDDNYH IFCLLPPLPE 360 IPKGVWRCPK CVMAECKRPP EAFGFEQATR EYTLQSFGEM ADSFKADYFN MPVHMVPTEL 420 VEKEFWRLVN SIEEDVTVEY GADIHSKEFG SGFPVSDSKR HLTPEEEEYA TSGWNLNVMP 480 VLEQSVLCHI NADISGMKVP WLYVGMVFSA FCWHIEDHWS YSINYLHWGE PKTWYGVPSL 540 AAEHLEEVMK KLTPELFDSQ PDLLHQLVTL MNPNTLMSHG VPVVRTNQCA GEFVITFPRA 600 YHSGFNQGYN FAEAVNFCTA DWLPAGRQCI EHYRRLRRYC VFSHEELICK MAACPEKLDL 660 NLAAAVHKEM FIMVQEERRL RKALLEKGIT EAEREAFELL PDDERQCIKC KTTCFLSALA 720 CYDCPDGLVC LSHINDLCKC SSSRQYLRYR YTLDELPAML HKLKVRAESF DTWANKVRVA 780 LEVEDGRKRS LEELRALESE ARERRFPNSE LLQRLKNCLS EAEACVSRAL GLVSGQEAGP 840 DRVAGLQMTL AELRDFLGQM NNLPCAMHQI GDVKGILEQV EAYQTEAREA LVSQPSSPGL 900 LQSLLERGQQ LGVEVPEAQQ LQRQVEQARW LDEVKRTLAP SARRGTLAIM RGLLVAGASV 960 APSPAVDKAQ AELQELLTIA ERWEEKAHLC LEARQKHPPA TLEAIIHEAE NIPVHLPNIQ 1020 SLKEALAKAR AWIADVDEIQ NGDHYPCLDD LEGLVAVGRD LPVGLEELRQ LELQVLTAHS 1080 WREKASKTFL KKNSCYTLLE VLCPCADAGS DSTKRSRWME KELGLYKSDT ELLGLSAQDL 1140 RDPGSVIVAF KEGEQKEKEG ILQLRRTNSA KPSPLALLTT ASSTASICVC GQVPAGVGAL 1200 QCDLCQDWFH GRCVTVPRLL SSQRSSLPSS PLLAWWEWDT KFLCPLCMRS RRPRLETILA 1260 LLVALQRLPV RLPEGEALQC LTERAISWQG RARQVLASEE VTALLGRLAE LRQRLQAESK 1320 PEESLAYPSD GGEGTGNMPK VQGLLENGDS VTSPEKVATE EGSGKRDLEL LSSILPQLSG 1380 PVLELPEATR APLEELMMEG DLLEVTLDEN HSIWQLLQAG QPPDLKRVQT LLELEKAERH 1440 GSRTRGRALE RRRRRKVDRG GEPDDPAREE LEPKRVRSSG PEAEEVQEEE ELEEETGGEV 1500 PPVPFPNSGS PSIQEDQDGL EPVLEAGSDT SAPFSTLTSR LLMSCPQQPS LQQL 1554Protein Fasta Sequence
>ENSMUSP00000108203.1|KDM5C;JARID1C;SMCX|Mus musculus MELGSDDFLPPPECPVFEPSWAEFRDPLGYIAKIRPIAEKSGICKIRPPADWQPPFAVEVDNFRFTPRIQRLNELEAQTRVKLNYLDQIAKFWEIQGSSLKIPNVERRILDLYSLSKIVVEEGGYETICKDRRWARVAQRLNYPPGKNIGSLLRSHYERIVYPYEMYQSGANLVQCNTRPFDNEEKDKEYKPHSIPLRQSVQPSKFNSYGRRAKRLQPDPEPTEEDIEKNPELKKLQIYGAGPKMMGLGLMAKDKTLRKKDKEGPECPPTVVVKEELGGDVKMESTSPKTFLEGKEELSHSPEPCTKMTMRLRRNHSNAQFIESYVCRMCSRGDEDDKLLLCDGCDDNYHIFCLLPPLPEIPKGVWRCPKCVMAECKRPPEAFGFEQATREYTLQSFGEMADSFKADYFNMPVHMVPTELVEKEFWRLVNSIEEDVTVEYGADIHSKEFGSGFPVSDSKRHLTPEEEEYATSGWNLNVMPVLEQSVLCHINADISGMKVPWLYVGMVFSAFCWHIEDHWSYSINYLHWGEPKTWYGVPSLAAEHLEEVMKKLTPELFDSQPDLLHQLVTLMNPNTLMSHGVPVVRTNQCAGEFVITFPRAYHSGFNQGYNFAEAVNFCTADWLPAGRQCIEHYRRLRRYCVFSHEELICKMAACPEKLDLNLAAAVHKEMFIMVQEERRLRKALLEKGITEAEREAFELLPDDERQCIKCKTTCFLSALACYDCPDGLVCLSHINDLCKCSSSRQYLRYRYTLDELPAMLHKLKVRAESFDTWANKVRVALEVEDGRKRSLEELRALESEARERRFPNSELLQRLKNCLSEAEACVSRALGLVSGQEAGPDRVAGLQMTLAELRDFLGQMNNLPCAMHQIGDVKGILEQVEAYQTEAREALVSQPSSPGLLQSLLERGQQLGVEVPEAQQLQRQVEQARWLDEVKRTLAPSARRGTLAIMRGLLVAGASVAPSPAVDKAQAELQELLTIAERWEEKAHLCLEARQKHPPATLEAIIHEAENIPVHLPNIQSLKEALAKARAWIADVDEIQNGDHYPCLDDLEGLVAVGRDLPVGLEELRQLELQVLTAHSWREKASKTFLKKNSCYTLLEVLCPCADAGSDSTKRSRWMEKELGLYKSDTELLGLSAQDLRDPGSVIVAFKEGEQKEKEGILQLRRTNSAKPSPLALLTTASSTASICVCGQVPAGVGALQCDLCQDWFHGRCVTVPRLLSSQRSSLPSSPLLAWWEWDTKFLCPLCMRSRRPRLETILALLVALQRLPVRLPEGEALQCLTERAISWQGRARQVLASEEVTALLGRLAELRQRLQAESKPEESLAYPSDGGEGTGNMPKVQGLLENGDSVTSPEKVATEEGSGKRDLELLSSILPQLSGPVLELPEATRAPLEELMMEGDLLEVTLDENHSIWQLLQAGQPPDLKRVQTLLELEKAERHGSRTRGRALERRRRRKVDRGGEPDDPAREELEPKRVRSSGPEAEEVQEEEELEEETGGEVPPVPFPNSGSPSIQEDQDGLEPVLEAGSDTSAPFSTLTSRLLMSCPQQPSLQQL
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Nucleotide Sequence (Fasta) | TTGTTCTTCC GCCAATGAAA TGAACTATTT TCTCTTAGCC TGAGAAATGT TTTTAACTAA 60 CCACCTCCAA ATAAGGGACA TATACAACCC GATTTCTTTC GGTCATCACA TGATGAAGGC 120 TTCCTAGGTT TTTTTCTGAC TCAAAGTAAA CGGAACTCGG AGAGACACCT TGCGGAGGGA 180 TCTGGTTTGT TGTGGTGAGG TACAGAGGTG GGGGGGAGGA GACGCTGACA AACCAAGATG 240 GCGGTGGCAG CGGTGAAACC TGCCGCGACT GGGACTTAAC TGTAGTAGTG AAGGCTTCAG 300 TAGTTGGGAG GCAGCGGTAA GGTGTGGAAG AAACGGAACA GGACTAAGAA CCTGTAAAAG 360 GAACCTCAGC CTGAGACTTT TAGAGCACGG CACCCGCCCC CCTAAGCCCT TGACGGGCGG 420 TGGCCGTCCT GCTTAGGGCC TAGACTCCGA GAAGTACCTC GGTTTCAGAC AGCGGCGGCG 480 CCATGCGTCC TTAAGGGCGA CCTGAGCCCT CCCGATCTCT GGCCCAGCCC TCGGGCCCAC 540 CATGGAGCTG GGGTCCGACG ATTTCCTACC GCCGCCGGAG TGTCCGGTGT TCGAGCCTAG 600 CTGGGCCGAG TTCCGAGACC CTCTTGGCTA CATCGCGAAA ATCAGACCCA TCGCCGAGAA 660 GTCCGGCATT TGCAAGATCC GCCCACCCGC GGACTGGCAG CCACCCTTTG CCGTGGAAGT 720 GGATAACTTC AGGTTTACTC CCCGAATCCA GAGGTTGAAT GAGCTGGAGG CCCAGACAAG 780 AGTGAAACTG AACTATTTGG ACCAGATTGC CAAATTCTGG GAGATCCAGG GCTCATCCTT 840 AAAGATTCCC AATGTAGAAC GGCGGATCTT GGACCTCTAT AGCCTCAGCA AAATTGTGGT 900 GGAAGAAGGT GGTTATGAAA CTATCTGCAA GGACCGTCGA TGGGCCCGTG TGGCCCAGCG 960 TCTCAACTAC CCACCTGGCA AAAACATTGG TTCCTTGCTA CGCTCTCACT ATGAACGCAT 1020 TGTTTATCCC TATGAAATGT ACCAGTCTGG AGCCAACCTT GTGCAGTGTA ACACACGCCC 1080 ATTTGATAAT GAGGAAAAGG ACAAGGAATA TAAACCCCAC AGCATCCCCC TTCGACAGTC 1140 TGTGCAGCCT TCCAAGTTCA ACAGTTATGG ACGACGGGCA AAGAGACTAC AGCCTGATCC 1200 GGAACCCACA GAGGAAGACA TTGAAAAGAA TCCAGAACTG AAGAAATTAC AGATATATGG 1260 AGCAGGCCCC AAGATGATGG GGCTGGGCCT AATGGCCAAA GATAAGACTC TGCGGAAAAA 1320 AGATAAAGAA GGGCCTGAGT GTCCCCCCAC TGTGGTGGTA AAGGAGGAAT TAGGTGGGGA 1380 TGTCAAGATG GAATCAACCT CACCCAAGAC CTTCCTAGAA GGCAAGGAGG AACTGAGTCA 1440 TAGCCCTGAG CCCTGCACCA AGATGACCAT GAGGCTTCGA AGGAACCACA GCAATGCCCA 1500 GTTTATTGAG TCATACGTAT GCCGAATGTG TTCCCGAGGA GATGAAGATG ACAAACTCTT 1560 ACTGTGTGAT GGCTGTGATG ACAATTACCA CATCTTTTGC CTGCTGCCTC CTTTGCCTGA 1620 AATCCCGAAA GGTGTCTGGA GGTGTCCAAA GTGTGTCATG GCGGAGTGTA AGCGGCCCCC 1680 TGAAGCCTTT GGCTTTGAGC AAGCTACCCG GGAATATACT CTGCAGAGCT TTGGAGAGAT 1740 GGCTGACTCC TTTAAAGCTG ACTACTTCAA CATGCCTGTG CATATGGTAC CCACAGAACT 1800 TGTAGAGAAG GAGTTTTGGC GGCTGGTGAA TAGCATCGAG GAAGACGTAA CTGTGGAGTA 1860 TGGGGCTGAC ATCCATTCCA AAGAATTTGG CAGCGGTTTC CCTGTCAGTG ACAGTAAGCG 1920 GCACCTAACC CCAGAGGAGG AGGAGTATGC TACAAGTGGT TGGAACCTGA ATGTGATGCC 1980 TGTATTGGAG CAGTCTGTAC TGTGCCACAT CAATGCAGAT ATATCTGGCA TGAAGGTACC 2040 GTGGCTGTAT GTGGGAATGG TCTTCTCAGC CTTTTGCTGG CATATTGAAG ATCACTGGAG 2100 TTACTCTATT AACTACCTCC ACTGGGGTGA GCCAAAAACC TGGTATGGAG TCCCATCGCT 2160 TGCAGCGGAA CACTTGGAAG AAGTGATGAA GAAGCTGACA CCTGAGCTTT TTGATAGCCA 2220 GCCTGATCTC CTTCACCAAC TCGTCACCCT CATGAATCCT AACACGCTCA TGTCCCATGG 2280 TGTGCCGGTT GTCCGCACAA ACCAGTGTGC AGGAGAATTT GTCATCACTT TTCCTCGTGC 2340 TTACCACAGT GGTTTCAACC AAGGCTACAA CTTTGCTGAG GCAGTCAACT TTTGCACTGC 2400 TGACTGGCTG CCTGCTGGGC GCCAATGCAT TGAGCACTAC CGCCGACTAC GAAGATACTG 2460 TGTCTTTTCT CATGAGGAGC TCATTTGCAA GATGGCTGCC TGCCCTGAGA AACTGGACCT 2520 GAACCTGGCA GCAGCTGTAC ATAAGGAGAT GTTCATTATG GTGCAAGAGG AGCGGCGTCT 2580 ACGAAAGGCT CTGTTGGAAA AAGGTATCAC CGAGGCTGAG CGAGAGGCTT TTGAGCTGCT 2640 TCCAGATGAT GAACGTCAGT GCATAAAGTG CAAGACCACA TGTTTCCTAT CTGCCCTGGC 2700 TTGCTATGAC TGCCCAGATG GCCTTGTCTG CCTTTCTCAC ATCAATGACC TCTGCAAGTG 2760 CTCCAGTAGC CGCCAGTACC TTCGGTATCG GTACACCTTG GATGAGCTCC CTGCCATGCT 2820 GCATAAACTG AAAGTTAGAG CTGAGTCCTT TGACACCTGG GCTAACAAAG TACGAGTGGC 2880 CCTGGAGGTG GAAGATGGGC GGAAGCGCAG CCTGGAAGAA CTGAGAGCAC TAGAATCTGA 2940 GGCTCGTGAG CGAAGGTTTC CTAACAGTGA GCTTCTACAG CGACTGAAAA ACTGCCTGAG 3000 TGAAGCAGAG GCTTGTGTGT CCCGGGCTCT GGGATTGGTC AGTGGCCAGG AAGCTGGCCC 3060 TGACAGGGTG GCTGGCCTAC AGATGACCCT GGCTGAGCTA CGGGATTTTC TGGGCCAGAT 3120 GAACAACCTG CCCTGTGCCA TGCACCAGAT TGGGGATGTC AAGGGTATTC TGGAACAGGT 3180 GGAAGCCTAC CAGACTGAGG CCCGTGAGGC CCTGGTCTCA CAGCCTTCCA GTCCAGGGCT 3240 GCTGCAGTCC TTGTTGGAGA GAGGACAACA GCTGGGTGTG GAGGTACCTG AAGCCCAGCA 3300 GCTCCAAAGG CAGGTGGAAC AGGCGCGGTG GCTGGATGAG GTAAAACGCA CGCTGGCTCC 3360 CTCTGCCCGA AGGGGTACCC TGGCCATCAT GCGGGGACTG TTGGTTGCGG GCGCCAGTGT 3420 AGCCCCTAGC CCTGCTGTGG ATAAGGCCCA GGCAGAGCTT CAGGAGCTGC TGACCATCGC 3480 TGAACGCTGG GAAGAGAAAG CCCACCTCTG CTTAGAGGCC AGGCAGAAGC ATCCACCAGC 3540 CACACTTGAG GCCATAATCC ATGAAGCAGA AAACATCCCT GTTCACTTGC CCAATATCCA 3600 GTCTCTCAAG GAGGCTCTTG CTAAGGCCCG GGCATGGATT GCTGATGTGG ATGAGATCCA 3660 AAATGGTGAC CACTACCCTT GCTTGGATGA CTTGGAGGGC CTCGTAGCTG TGGGTCGGGA 3720 CCTCCCTGTG GGGCTGGAGG AACTGAGACA GCTAGAGCTA CAGGTATTGA CAGCACACTC 3780 CTGGAGAGAA AAGGCCTCCA AGACCTTCCT CAAGAAGAAC TCCTGCTATA CATTATTGGA 3840 GGTGCTCTGC CCGTGTGCAG ACGCCGGCTC AGACAGCACC AAACGCAGCC GGTGGATGGA 3900 GAAGGAGCTG GGGTTGTACA AATCTGACAC AGAGCTGTTG GGGCTGTCTG CGCAGGACCT 3960 CAGGGACCCA GGCTCTGTGA TCGTGGCCTT CAAAGAGGGG GAGCAGAAGG AGAAGGAAGG 4020 GATACTGCAG CTTCGTCGTA CCAACTCAGC CAAGCCAAGT CCACTGGCAC TGTTGACAAC 4080 AGCCTCCTCT ACAGCTTCTA TCTGCGTGTG TGGGCAAGTG CCAGCTGGGG TGGGAGCTCT 4140 GCAGTGTGAC CTGTGTCAGG ACTGGTTCCA TGGGCGCTGT GTGACAGTAC CCCGCCTCCT 4200 CAGCTCCCAG AGGTCCAGTC TTCCCTCATC CCCACTGCTG GCCTGGTGGG AATGGGACAC 4260 CAAATTCTTG TGCCCTCTGT GTATGCGCTC ACGGCGCCCA CGCTTGGAAA CCATCCTGGC 4320 ACTGCTGGTA GCCCTACAGA GACTGCCTGT GCGGCTGCCT GAGGGTGAGG CTCTACAGTG 4380 CCTCACAGAG AGAGCCATCA GCTGGCAAGG CCGTGCCAGA CAGGTTTTGG CCTCTGAGGA 4440 AGTGACTGCT CTGTTGGGAC GGCTGGCTGA ACTGCGCCAA CGGCTACAGG CTGAATCCAA 4500 GCCTGAGGAG TCCCTGGCTT ACCCTTCAGA TGGTGGAGAG GGCACTGGCA ATATGCCGAA 4560 GGTCCAGGGG CTGTTGGAGA ATGGGGACAG TGTGACCAGT CCTGAAAAGG TAGCCACAGA 4620 GGAGGGCTCA GGTAAGAGAG ATCTGGAGCT GCTATCCTCA ATATTACCAC AGTTGTCTGG 4680 CCCTGTGTTG GAACTGCCTG AGGCAACCCG AGCCCCACTG GAGGAACTTA TGATGGAAGG 4740 GGATCTGCTT GAGGTGACCC TAGATGAGAA TCATAGCATC TGGCAGCTGC TGCAGGCTGG 4800 GCAGCCTCCA GACTTGAAGA GGGTCCAGAC ACTTCTGGAG CTGGAGAAGG CAGAGCGCCA 4860 TGGGAGTCGG ACACGAGGCC GAGCCCTAGA GAGGAGACGA CGGAGGAAGG TGGATCGGGG 4920 TGGGGAGCCG GATGACCCGG CACGAGAGGA GCTAGAGCCA AAGAGGGTAC GAAGCTCAGG 4980 ACCAGAAGCC GAGGAAGTCC AGGAGGAAGA GGAGCTGGAG GAGGAGACTG GGGGTGAGGT 5040 CCCTCCTGTA CCCTTCCCCA ACAGTGGCAG CCCCAGCATC CAGGAGGACC AGGATGGCTT 5100 AGAACCAGTG TTAGAGGCTG GTTCTGACAC CTCAGCCCCT TTCTCTACTC TGACTTCCCG 5160 GCTGTTGATG TCCTGCCCAC AGCAGCCATC TCTGCAACAA TTGTGACAGT GGCTGAGCCT 5220 AGCACAGACC CCAACAAAGA TCCTTCCTTG GCCTCAAGGA TCCTTTCTGA CCATCAAGCC 5280 TGCTTCTTGG AGGTGGGCGG GTAGGTGGAG AGACTTCCCC CTCACCACCA TCCCCAAGAT 5340 CGTGACTTTT ATATTCTGAC TCCAAGGTAT TGTTCAGACC TCAGCTCCTG GGGGCCGGCC 5400 CCTGGAGTCC TGCGTCCCTG GTAACCTCTA ACCAGCATTC CCAGACACCA GAGGCAGATA 5460 GACAGGTGGG CAGGGGATCT ACTGGGGCTG GGCCAGCACC ATTCCAGAGA CAAATCCAGG 5520 GCACATGCAA ACTGGGGGAC CTCTCCCTTA TCCCCAGTTC TGACCCTGGG TCAGGCCATG 5580 CTACACTAAC CTTCCCTCCC CACTTCACAC TTTTGCTCCC CCCCCCCTCC CAGTCCATTT 5640 TACTTCTTTC CTCTCCCCTT CATCTTTTCC CTTCCCCTTA CTGTTCCACC CAGGAGGAGG 5700 AAACTTCACA TAGCTGTCCT CACCCTTTTA TTTTAAATGA ATTTTGTTGG GGTTGAGCAG 5760 GGCTGCCTAT GGTCTGAAGG CTTTTGGTGC TTGTCCACAC ACCCACCTCA ACCCTTCCTG 5820 CCCATCCTCC CCTATCTCCT TTCCTCCTCC TGGGTTCATG CTGTAATAAA GAAGATTGTT 5880 GGTGTGTAAT TAATTTGTTC
5901Nucleotide Fasta Sequence
>ENSMUSP00000108203.1|PHD|Mus musculus TTGTTCTTCCGCCAATGAAATGAACTATTTTCTCTTAGCCTGAGAAATGTTTTTAACTAACCACCTCCAAATAAGGGACATATACAACCCGATTTCTTTCGGTCATCACATGATGAAGGCTTCCTAGGTTTTTTTCTGACTCAAAGTAAACGGAACTCGGAGAGACACCTTGCGGAGGGATCTGGTTTGTTGTGGTGAGGTACAGAGGTGGGGGGGAGGAGACGCTGACAAACCAAGATGGCGGTGGCAGCGGTGAAACCTGCCGCGACTGGGACTTAACTGTAGTAGTGAAGGCTTCAGTAGTTGGGAGGCAGCGGTAAGGTGTGGAAGAAACGGAACAGGACTAAGAACCTGTAAAAGGAACCTCAGCCTGAGACTTTTAGAGCACGGCACCCGCCCCCCTAAGCCCTTGACGGGCGGTGGCCGTCCTGCTTAGGGCCTAGACTCCGAGAAGTACCTCGGTTTCAGACAGCGGCGGCGCCATGCGTCCTTAAGGGCGACCTGAGCCCTCCCGATCTCTGGCCCAGCCCTCGGGCCCACCATGGAGCTGGGGTCCGACGATTTCCTACCGCCGCCGGAGTGTCCGGTGTTCGAGCCTAGCTGGGCCGAGTTCCGAGACCCTCTTGGCTACATCGCGAAAATCAGACCCATCGCCGAGAAGTCCGGCATTTGCAAGATCCGCCCACCCGCGGACTGGCAGCCACCCTTTGCCGTGGAAGTGGATAACTTCAGGTTTACTCCCCGAATCCAGAGGTTGAATGAGCTGGAGGCCCAGACAAGAGTGAAACTGAACTATTTGGACCAGATTGCCAAATTCTGGGAGATCCAGGGCTCATCCTTAAAGATTCCCAATGTAGAACGGCGGATCTTGGACCTCTATAGCCTCAGCAAAATTGTGGTGGAAGAAGGTGGTTATGAAACTATCTGCAAGGACCGTCGATGGGCCCGTGTGGCCCAGCGTCTCAACTACCCACCTGGCAAAAACATTGGTTCCTTGCTACGCTCTCACTATGAACGCATTGTTTATCCCTATGAAATGTACCAGTCTGGAGCCAACCTTGTGCAGTGTAACACACGCCCATTTGATAATGAGGAAAAGGACAAGGAATATAAACCCCACAGCATCCCCCTTCGACAGTCTGTGCAGCCTTCCAAGTTCAACAGTTATGGACGACGGGCAAAGAGACTACAGCCTGATCCGGAACCCACAGAGGAAGACATTGAAAAGAATCCAGAACTGAAGAAATTACAGATATATGGAGCAGGCCCCAAGATGATGGGGCTGGGCCTAATGGCCAAAGATAAGACTCTGCGGAAAAAAGATAAAGAAGGGCCTGAGTGTCCCCCCACTGTGGTGGTAAAGGAGGAATTAGGTGGGGATGTCAAGATGGAATCAACCTCACCCAAGACCTTCCTAGAAGGCAAGGAGGAACTGAGTCATAGCCCTGAGCCCTGCACCAAGATGACCATGAGGCTTCGAAGGAACCACAGCAATGCCCAGTTTATTGAGTCATACGTATGCCGAATGTGTTCCCGAGGAGATGAAGATGACAAACTCTTACTGTGTGATGGCTGTGATGACAATTACCACATCTTTTGCCTGCTGCCTCCTTTGCCTGAAATCCCGAAAGGTGTCTGGAGGTGTCCAAAGTGTGTCATGGCGGAGTGTAAGCGGCCCCCTGAAGCCTTTGGCTTTGAGCAAGCTACCCGGGAATATACTCTGCAGAGCTTTGGAGAGATGGCTGACTCCTTTAAAGCTGACTACTTCAACATGCCTGTGCATATGGTACCCACAGAACTTGTAGAGAAGGAGTTTTGGCGGCTGGTGAATAGCATCGAGGAAGACGTAACTGTGGAGTATGGGGCTGACATCCATTCCAAAGAATTTGGCAGCGGTTTCCCTGTCAGTGACAGTAAGCGGCACCTAACCCCAGAGGAGGAGGAGTATGCTACAAGTGGTTGGAACCTGAATGTGATGCCTGTATTGGAGCAGTCTGTACTGTGCCACATCAATGCAGATATATCTGGCATGAAGGTACCGTGGCTGTATGTGGGAATGGTCTTCTCAGCCTTTTGCTGGCATATTGAAGATCACTGGAGTTACTCTATTAACTACCTCCACTGGGGTGAGCCAAAAACCTGGTATGGAGTCCCATCGCTTGCAGCGGAACACTTGGAAGAAGTGATGAAGAAGCTGACACCTGAGCTTTTTGATAGCCAGCCTGATCTCCTTCACCAACTCGTCACCCTCATGAATCCTAACACGCTCATGTCCCATGGTGTGCCGGTTGTCCGCACAAACCAGTGTGCAGGAGAATTTGTCATCACTTTTCCTCGTGCTTACCACAGTGGTTTCAACCAAGGCTACAACTTTGCTGAGGCAGTCAACTTTTGCACTGCTGACTGGCTGCCTGCTGGGCGCCAATGCATTGAGCACTACCGCCGACTACGAAGATACTGTGTCTTTTCTCATGAGGAGCTCATTTGCAAGATGGCTGCCTGCCCTGAGAAACTGGACCTGAACCTGGCAGCAGCTGTACATAAGGAGATGTTCATTATGGTGCAAGAGGAGCGGCGTCTACGAAAGGCTCTGTTGGAAAAAGGTATCACCGAGGCTGAGCGAGAGGCTTTTGAGCTGCTTCCAGATGATGAACGTCAGTGCATAAAGTGCAAGACCACATGTTTCCTATCTGCCCTGGCTTGCTATGACTGCCCAGATGGCCTTGTCTGCCTTTCTCACATCAATGACCTCTGCAAGTGCTCCAGTAGCCGCCAGTACCTTCGGTATCGGTACACCTTGGATGAGCTCCCTGCCATGCTGCATAAACTGAAAGTTAGAGCTGAGTCCTTTGACACCTGGGCTAACAAAGTACGAGTGGCCCTGGAGGTGGAAGATGGGCGGAAGCGCAGCCTGGAAGAACTGAGAGCACTAGAATCTGAGGCTCGTGAGCGAAGGTTTCCTAACAGTGAGCTTCTACAGCGACTGAAAAACTGCCTGAGTGAAGCAGAGGCTTGTGTGTCCCGGGCTCTGGGATTGGTCAGTGGCCAGGAAGCTGGCCCTGACAGGGTGGCTGGCCTACAGATGACCCTGGCTGAGCTACGGGATTTTCTGGGCCAGATGAACAACCTGCCCTGTGCCATGCACCAGATTGGGGATGTCAAGGGTATTCTGGAACAGGTGGAAGCCTACCAGACTGAGGCCCGTGAGGCCCTGGTCTCACAGCCTTCCAGTCCAGGGCTGCTGCAGTCCTTGTTGGAGAGAGGACAACAGCTGGGTGTGGAGGTACCTGAAGCCCAGCAGCTCCAAAGGCAGGTGGAACAGGCGCGGTGGCTGGATGAGGTAAAACGCACGCTGGCTCCCTCTGCCCGAAGGGGTACCCTGGCCATCATGCGGGGACTGTTGGTTGCGGGCGCCAGTGTAGCCCCTAGCCCTGCTGTGGATAAGGCCCAGGCAGAGCTTCAGGAGCTGCTGACCATCGCTGAACGCTGGGAAGAGAAAGCCCACCTCTGCTTAGAGGCCAGGCAGAAGCATCCACCAGCCACACTTGAGGCCATAATCCATGAAGCAGAAAACATCCCTGTTCACTTGCCCAATATCCAGTCTCTCAAGGAGGCTCTTGCTAAGGCCCGGGCATGGATTGCTGATGTGGATGAGATCCAAAATGGTGACCACTACCCTTGCTTGGATGACTTGGAGGGCCTCGTAGCTGTGGGTCGGGACCTCCCTGTGGGGCTGGAGGAACTGAGACAGCTAGAGCTACAGGTATTGACAGCACACTCCTGGAGAGAAAAGGCCTCCAAGACCTTCCTCAAGAAGAACTCCTGCTATACATTATTGGAGGTGCTCTGCCCGTGTGCAGACGCCGGCTCAGACAGCACCAAACGCAGCCGGTGGATGGAGAAGGAGCTGGGGTTGTACAAATCTGACACAGAGCTGTTGGGGCTGTCTGCGCAGGACCTCAGGGACCCAGGCTCTGTGATCGTGGCCTTCAAAGAGGGGGAGCAGAAGGAGAAGGAAGGGATACTGCAGCTTCGTCGTACCAACTCAGCCAAGCCAAGTCCACTGGCACTGTTGACAACAGCCTCCTCTACAGCTTCTATCTGCGTGTGTGGGCAAGTGCCAGCTGGGGTGGGAGCTCTGCAGTGTGACCTGTGTCAGGACTGGTTCCATGGGCGCTGTGTGACAGTACCCCGCCTCCTCAGCTCCCAGAGGTCCAGTCTTCCCTCATCCCCACTGCTGGCCTGGTGGGAATGGGACACCAAATTCTTGTGCCCTCTGTGTATGCGCTCACGGCGCCCACGCTTGGAAACCATCCTGGCACTGCTGGTAGCCCTACAGAGACTGCCTGTGCGGCTGCCTGAGGGTGAGGCTCTACAGTGCCTCACAGAGAGAGCCATCAGCTGGCAAGGCCGTGCCAGACAGGTTTTGGCCTCTGAGGAAGTGACTGCTCTGTTGGGACGGCTGGCTGAACTGCGCCAACGGCTACAGGCTGAATCCAAGCCTGAGGAGTCCCTGGCTTACCCTTCAGATGGTGGAGAGGGCACTGGCAATATGCCGAAGGTCCAGGGGCTGTTGGAGAATGGGGACAGTGTGACCAGTCCTGAAAAGGTAGCCACAGAGGAGGGCTCAGGTAAGAGAGATCTGGAGCTGCTATCCTCAATATTACCACAGTTGTCTGGCCCTGTGTTGGAACTGCCTGAGGCAACCCGAGCCCCACTGGAGGAACTTATGATGGAAGGGGATCTGCTTGAGGTGACCCTAGATGAGAATCATAGCATCTGGCAGCTGCTGCAGGCTGGGCAGCCTCCAGACTTGAAGAGGGTCCAGACACTTCTGGAGCTGGAGAAGGCAGAGCGCCATGGGAGTCGGACACGAGGCCGAGCCCTAGAGAGGAGACGACGGAGGAAGGTGGATCGGGGTGGGGAGCCGGATGACCCGGCACGAGAGGAGCTAGAGCCAAAGAGGGTACGAAGCTCAGGACCAGAAGCCGAGGAAGTCCAGGAGGAAGAGGAGCTGGAGGAGGAGACTGGGGGTGAGGTCCCTCCTGTACCCTTCCCCAACAGTGGCAGCCCCAGCATCCAGGAGGACCAGGATGGCTTAGAACCAGTGTTAGAGGCTGGTTCTGACACCTCAGCCCCTTTCTCTACTCTGACTTCCCGGCTGTTGATGTCCTGCCCACAGCAGCCATCTCTGCAACAATTGTGACAGTGGCTGAGCCTAGCACAGACCCCAACAAAGATCCTTCCTTGGCCTCAAGGATCCTTTCTGACCATCAAGCCTGCTTCTTGGAGGTGGGCGGGTAGGTGGAGAGACTTCCCCCTCACCACCATCCCCAAGATCGTGACTTTTATATTCTGACTCCAAGGTATTGTTCAGACCTCAGCTCCTGGGGGCCGGCCCCTGGAGTCCTGCGTCCCTGGTAACCTCTAACCAGCATTCCCAGACACCAGAGGCAGATAGACAGGTGGGCAGGGGATCTACTGGGGCTGGGCCAGCACCATTCCAGAGACAAATCCAGGGCACATGCAAACTGGGGGACCTCTCCCTTATCCCCAGTTCTGACCCTGGGTCAGGCCATGCTACACTAACCTTCCCTCCCCACTTCACACTTTTGCTCCCCCCCCCCTCCCAGTCCATTTTACTTCTTTCCTCTCCCCTTCATCTTTTCCCTTCCCCTTACTGTTCCACCCAGGAGGAGGAAACTTCACATAGCTGTCCTCACCCTTTTATTTTAAATGAATTTTGTTGGGGTTGAGCAGGGCTGCCTATGGTCTGAAGGCTTTTGGTGCTTGTCCACACACCCACCTCAACCCTTCCTGCCCATCCTCCCCTATCTCCTTTCCTCCTCCTGGGTTCATGCTGTAATAAAGAAGATTGTTGGTGTGTAATTAATTTGTTC
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Sequence Source |
Ensembl |
Keyword |
KW-0025--Alternative splicing KW-0090--Biological rhythms KW-0156--Chromatin regulator KW-0181--Complete proteome KW-0223--Dioxygenase KW-0408--Iron KW-0479--Metal-binding KW-0539--Nucleus KW-0560--Oxidoreductase KW-0597--Phosphoprotein KW-1185--Reference proteome KW-0677--Repeat KW-0678--Repressor KW-0804--Transcription KW-0805--Transcription regulation KW-0862--Zinc KW-0863--Zinc-finger --
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Interpro |
IPR001606--ARID_dom IPR003347--JmjC_dom IPR003349--JmjN IPR013637--Lys_sp_deMease-like_dom IPR019786--Zinc_finger_PHD-type_CS IPR004198--Znf_C5HC2 IPR011011--Znf_FYVE_PHD IPR001965--Znf_PHD IPR019787--Znf_PHD-finger IPR013083--Znf_RING/FYVE/PHD
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PROSITE |
PS51011--ARID PS51184--JMJC PS51183--JMJN PS01359--ZF_PHD_1 PS50016--ZF_PHD_2
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Pfam |
PF01388--ARID PF02373--JmjC PF02375--JmjN PF00628--PHD PF08429--PLU-1 PF02928--zf-C5HC2
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Gene Ontology |
GO:0005737--C:cytoplasm GO:0005634--C:nucleus GO:0003677--F:DNA binding GO:0032453--F:histone demethylase activity (H3-K4 specific) GO:0042802--F:identical protein binding GO:0016706--F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors GO:0001085--F:RNA polymerase II transcription factor binding GO:0008270--F:zinc ion binding GO:0034720--P:histone H3-K4 demethylation GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter GO:0045892--P:negative regulation of transcription, DNA-templated GO:0042752--P:regulation of circadian rhythm GO:0048511--P:rhythmic process GO:0006351--P:transcription, DNA-templated
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Orthology |
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Created Date |
25-Jun-2016 |