WERAM Information


Tag Content
WERAM ID WERAM-Drm-0053
Ensembl Protein ID FBpp0085699
Uniprot Accession Q4V5A7; Q4V5A7_DROME
Genbank Protein ID NP_611401.2
Protein Name IP14655p
Genbank Nucleotide ID NM_137557.3
Gene Name TBRD2;CG7229;Dmel_CG7229
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
FBgn0034423 FBtr0086511 FBpp0085699
Details
Type Family Domain Substrates AA References (PMIDs)
Ac_Reader Bromodomain Bromodomain K 25251222
Status Reviewed
Classification
Type Family E-value Score Start End
Ac_Reader Bromodomain 7.90e-20 71.3 48 218
Organism Drosophila melanogaster
NCBI Taxa ID 7227
Functional Description
(View)
Domain Profile
  Ac_Reader Bromodomain

    BROMO.txt   2 ehevsepFrepvdpq.leipdYydiikePmdLstikerleegnYsspeefvkDvrlifnNakaynenkssvq 72 
+++++ F epvd + l +p Yy++i++Pmd+ ti +r+++++Y+s++e ++D+++i++N+ +n+ ++ v+
FBpp0085699 48 KKKYALDFLEPVDTEaLMVPTYYTVIHRPMDIGTIVKRVQNNYYKSVNEAIADFKQIISNCFLFNRSGDVVY 119
5788999***********************************************************999886 PP
BROMO.txt 35 ikerleegnYsspeefvkDvrl 56
++++++++++s++ef +v
FBpp0085699 197 LQKKVDRQYFKSVNEFCLHVDG 218
5799************988765 PP

Protein Sequence
(Fasta)
MASCKPLSVK LKLPNRVQPE FIPHPGMAGR YTNKLHYFKK HLLDEARKKK YALDFLEPVD 60
TEALMVPTYY TVIHRPMDIG TIVKRVQNNY YKSVNEAIAD FKQIISNCFL FNRSGDVVYR 120
KGQMLEKFFH KKLRGMPSGP EVPCNRDPKA VGRPRTNAPS SAQTERKCRE LLKKLQSITN 180
QTDAMTRNFF SNKWDSLQKK VDRQYFKSVN EFCLHVDGCF RKYHEPAKIL YERVFNQPAA 240
WCTSMNGNSS LESALNAADL NELLAAAKLT VNSLMQCVQM PGSGEPLTAK SLVETFCDTL 300
NKMINKMEAG QRNSPNPSSS KRQKMSPEQE TDLVQGEFKP AMELLSGNEI DNLMAVSIES 360
SDDEAIDASM RITDADRCAT QKLFAKLPTN AMKEIIHMVQ QIEGFSSENC GDLSFDVKGL 420
ATDTMIMMKS AVTKATRAHS KLKLKDMQPS EKEGLQRALQ SQLVNITRML NKNRRRCGPL 480
INFRNKNNTA NNVVRKRATA PLTAKLKPLQ ANVMAPQLGA GVVETHNLSD TSDDDVSAPV 540
KLSAIGGTPM RNLPINSNPL QMQPIRSPPK LPHVVELQMS SSSSSESEMK SKSGRLSRSR 600
SRSMSDTKLR PRSNSSASSR SNSSSSSGSN AGSSSGSRSR SSSSSSSSSN NSSESNDSSD 660
VEVVPNVPEG QLRA 674
Nucleotide Sequence
(Fasta)
AAAGCGGACG GTCGAACGGC AAAAGTGTTC CCAAAACTCA ATCGTAATCG TAGTCAAATT 60
CGAGTTTATA TTTGTGTAAA ATTGAAAGAG ACACGTTTTC AAAAATCGAA ACAAACGAAC 120
AACCAGTAAC CAGTAACTGA AAAATATATC TCTAGCATGG CATCTTGCAA GCCGCTTTCC 180
GTAAAACTAA AACTCCCAAA TCGTGTCCAA CCCGAGTTTA TACCGCATCC CGGAATGGCG 240
GGTCGTTATA CCAATAAGTT GCATTACTTC AAGAAGCATT TGCTCGACGA GGCTCGCAAG 300
AAGAAGTATG CCTTGGACTT CTTGGAGCCC GTGGACACGG AGGCTCTGAT GGTGCCCACA 360
TACTACACGG TTATCCATCG TCCCATGGAT ATCGGTACCA TTGTGAAAAG AGTTCAGAAC 420
AACTACTATA AATCTGTCAA TGAAGCGATT GCCGATTTCA AGCAAATTAT TAGCAATTGC 480
TTCCTATTCA ATCGATCCGG CGATGTCGTT TACCGCAAGG GCCAGATGCT GGAGAAGTTC 540
TTTCACAAGA AACTCCGAGG CATGCCGTCT GGTCCAGAGG TGCCCTGCAA TAGGGATCCC 600
AAGGCGGTGG GCAGGCCTAG GACCAATGCT CCTAGTTCCG CGCAGACGGA ACGCAAGTGC 660
CGGGAATTAT TGAAGAAGTT GCAGAGCATC ACCAATCAGA CAGATGCCAT GACGCGCAAT 720
TTCTTCAGTA ACAAGTGGGA TTCGTTGCAA AAGAAAGTTG ATCGCCAGTA CTTCAAGTCT 780
GTCAATGAAT TTTGCTTGCA TGTGGATGGC TGCTTTAGAA AGTACCACGA ACCGGCTAAA 840
ATCCTCTACG AAAGAGTCTT TAATCAGCCG GCGGCTTGGT GTACTTCCAT GAATGGAAAC 900
TCATCGCTGG AATCTGCTTT GAATGCCGCA GATCTAAATG AACTACTGGC TGCCGCCAAG 960
TTAACGGTAA ATAGCTTGAT GCAGTGCGTC CAAATGCCCG GTTCCGGGGA ACCTCTGACA 1020
GCCAAGAGTT TGGTGGAGAC TTTCTGTGAC ACCTTAAACA AGATGATAAA CAAAATGGAG 1080
GCAGGTCAAC GAAATTCTCC AAACCCATCA TCTAGCAAAC GACAGAAGAT GAGCCCCGAG 1140
CAGGAAACGG ATTTGGTCCA AGGCGAATTT AAGCCAGCTA TGGAGTTGTT AAGTGGAAAT 1200
GAAATAGATA ACCTCATGGC AGTTAGCATT GAATCCTCAG ATGATGAAGC TATCGATGCC 1260
TCAATGCGTA TCACTGACGC GGATCGATGT GCCACACAGA AATTATTTGC CAAGCTTCCG 1320
ACAAACGCCA TGAAGGAGAT AATTCACATG GTCCAGCAAA TCGAAGGATT TTCCTCAGAG 1380
AACTGTGGAG ATCTGAGCTT CGATGTCAAA GGTCTCGCCA CGGATACTAT GATCATGATG 1440
AAAAGTGCCG TCACCAAGGC AACTAGGGCC CATAGCAAGC TGAAGCTCAA GGACATGCAG 1500
CCTTCGGAAA AGGAAGGACT TCAGCGGGCA CTGCAGTCGC AGCTGGTGAA CATTACACGG 1560
ATGCTCAACA AAAATCGTCG CCGATGTGGT CCCTTGATCA ATTTCAGGAA TAAAAACAAC 1620
ACTGCCAATA ACGTGGTGCG TAAGAGAGCA ACTGCTCCGC TAACCGCCAA ATTGAAGCCG 1680
CTACAGGCTA ATGTAATGGC TCCACAATTG GGAGCAGGTG TTGTTGAGAC TCACAATCTG 1740
AGCGATACCA GCGACGATGA CGTCTCCGCT CCGGTAAAAC TGTCGGCTAT TGGTGGCACT 1800
CCAATGAGGA ATCTCCCAAT AAATAGTAAT CCTTTGCAAA TGCAACCCAT CAGATCCCCC 1860
CCCAAGTTGC CACACGTTGT CGAACTCCAG ATGAGCAGCA GCAGCAGCAG CGAGTCGGAA 1920
ATGAAATCCA AGTCCGGCAG ACTTTCTAGG TCCAGGTCCA GGTCCATGTC CGACACCAAG 1980
TTGAGACCCA GGTCAAACTC CAGCGCCAGC TCTAGATCTA ACTCTAGTTC TAGCTCTGGC 2040
TCCAACGCTG GCTCCAGCTC AGGGTCGCGC TCCAGATCAA GCTCCAGTTC CAGTTCATCT 2100
TCGAACAACA GCTCCGAGTC CAACGATTCC TCTGACGTTG AAGTGGTCCC CAATGTACCC 2160
GAAGGACAGC TGAGGGCCTA ATCCTCATAA AGAAGTCTTA TGAATTCTTG CATTTTATGT 2220
ATATGTAAAA AAAAGGGGGG TTTCACTACA AATATCCCAA ATATAAGAAA ATAAAAACTG 2280
TAAACACCTA TATTACACAT TCATGTGTAC ATATATGGTT GGACAAGAAA CT 2333
Sequence Source Ensembl
Keyword

KW-0103--Bromodomain
KW-0181--Complete proteome
KW-1185--Reference proteome
--

Interpro

IPR001487--Bromodomain
IPR018359--Bromodomain_CS
IPR027353--NET_dom

PROSITE

PS00633--BROMODOMAIN_1
PS50014--BROMODOMAIN_2
PS51525--NET

Pfam

PF00439--Bromodomain

Gene Ontology

GO:0005694--C:chromosome
GO:0016604--C:nuclear body
GO:0000790--C:nuclear chromatin
GO:0005730--C:nucleolus
GO:0007283--P:spermatogenesis

Orthology
WERAM ID Ensembl Protein ID Species Identity E-value Score
WERAM-Ocp-0032 ENSOPRP00000002696.1 Ochotona princeps 44 4e-25 114
WERAM-Poa-0009 ENSPPYP00000001343.1 Pongo abelii 40 4e-25 114
WERAM-Ict-0035 ENSSTOP00000002736.2 Ictidomys tridecemlineatus 44 7e-25 113
WERAM-Pof-0083 ENSPFOP00000007371.2 Poecilia formosa 41 8e-25 113
WERAM-Hos-0132 ENSP00000384051.1 Homo sapiens 40 8e-25 112
WERAM-Orc-0168 ENSOCUP00000015006.3 Oryctolagus cuniculus 42 9e-25 112
WERAM-Nol-0111 ENSNLEP00000012659.1 Nomascus leucogenys 40 1e-24 112
WERAM-Bot-0223 ENSBTAP00000004850.5 Bos taurus 40 1e-24 112
WERAM-Mum-0096 ENSMUSP00000031215.8 Mus musculus 41 1e-24 112
WERAM-Myl-0068 ENSMLUP00000005696.2 Myotis lucifugus 39 1e-24 112
WERAM-Ran-0018 ENSRNOP00000058256.2 Rattus norvegicus 37 2e-24 111
WERAM-Pat-0007 ENSPTRP00000001644.4 Pan troglodytes 43 2e-24 111
WERAM-Paa-0051 ENSPANP00000003567.1 Papio anubis 43 2e-24 111
WERAM-Orla-0148 ENSORLP00000017453.1 Oryzias latipes 40 4e-24 110
WERAM-Fia-0029 ENSFALP00000001836.1 Ficedula albicollis 39 5e-24 110
WERAM-Xim-0224 ENSXMAP00000018689.1 Xiphophorus maculatus 41 5e-24 110
WERAM-Mup-0046 ENSMPUP00000004278.1 Mustela putorius furo 43 5e-24 110
WERAM-Eqc-0123 ENSECAP00000013753.1 Equus caballus 39 7e-24 110
WERAM-Chs-0015 ENSCSAP00000016562.1 Chlorocebus sabaeus 42 7e-24 110
WERAM-Gaa-0037 ENSGACP00000005692.1 Gasterosteus aculeatus 42 7e-24 110
WERAM-Leo-0036 ENSLOCP00000005834.1 Lepisosteus oculatus 41 2e-23 108
WERAM-Gam-0156 ENSGMOP00000015464.1 Gadus morhua 35 2e-23 108
WERAM-Otg-0019 ENSOGAP00000000893.2 Otolemur garnettii 42 2e-23 108
WERAM-Ova-0171 ENSOARP00000017265.1 Ovis aries 43 2e-23 108
WERAM-Dar-0221 ENSDARP00000130622.1 Danio rerio 42 3e-23 107
WERAM-Mim-0130 ENSMICP00000013048.1 Microcebus murinus 40 3e-23 107
WERAM-Mod-0096 ENSMODP00000014906.4 Monodelphis domestica 37 3e-23 107
WERAM-Cap-0043 ENSCPOP00000003467.2 Cavia porcellus 44 4e-23 107
WERAM-Fec-0165 ENSFCAP00000017154.1 Felis catus 40 4e-23 107
WERAM-Orn-0225 ENSONIP00000024235.1 Oreochromis niloticus 43 4e-23 107
WERAM-Pem-0081 ENSPMAP00000008773.1 Petromyzon marinus 40 4e-23 107
WERAM-Loa-0127 ENSLAFP00000011699.3 Loxodonta africana 42 5e-23 107
WERAM-Vip-0103 ENSVPAP00000009601.1 Vicugna pacos 39 8e-23 106
WERAM-Lac-0047 ENSLACP00000006835.1 Latimeria chalumnae 42 1e-22 106
WERAM-Tub-0073 ENSTBEP00000009277.1 Tupaia belangeri 43 1e-22 105
WERAM-Ora-0083 ENSOANP00000013848.2 Ornithorhynchus anatinus 41 1e-22 105
WERAM-Pes-0007 ENSPSIP00000002650.1 Pelodiscus sinensis 33 1e-22 105
WERAM-Asm-0150 ENSAMXP00000014454.1 Astyanax mexicanus 39 1e-22 105
WERAM-Aim-0034 ENSAMEP00000002443.1 Ailuropoda melanoleuca 40 2e-22 105
WERAM-Ten-0212 ENSTNIP00000021345.1 Tetraodon nigroviridis 42 2e-22 105
WERAM-Chh-0100 ENSCHOP00000011481.1 Choloepus hoffmanni 38 2e-22 105
WERAM-Sus-0153 ENSSSCP00000019596.1 Sus scrofa 40 2e-22 105
WERAM-Tut-0179 ENSTTRP00000015157.1 Tursiops truncatus 40 2e-22 105
WERAM-Caj-0229 ENSCJAP00000047417.1 Callithrix jacchus 39 2e-22 105
WERAM-Sah-0090 ENSSHAP00000010568.1 Sarcophilus harrisii 41 2e-22 104
WERAM-Caf-0165 ENSCAFP00000023676.4 Canis familiaris 40 2e-22 104
WERAM-Ect-0061 ENSETEP00000006671.1 Echinops telfairi 38 3e-22 104
WERAM-Mae-0088 ENSMEUP00000008845.1 Macropus eugenii 41 3e-22 104
WERAM-Ptv-0180 ENSPVAP00000015952.1 Pteropus vampyrus 40 3e-22 104
WERAM-Anc-0036 ENSACAP00000004148.2 Anolis carolinensis 39 3e-22 104
WERAM-Tar-0047 ENSTRUP00000011219.1 Takifugu rubripes 42 3e-22 104
WERAM-Mam-0196 ENSMMUP00000028168.2 Macaca mulatta 39 4e-22 104
WERAM-Gog-0122 ENSGGOP00000010164.2 Gorilla gorilla 39 4e-22 103
WERAM-Dio-0036 ENSDORP00000004207.1 Dipodomys ordii 37 4e-22 103
WERAM-Prc-0094 ENSPCAP00000008495.1 Procavia capensis 38 5e-22 103
WERAM-Soa-0112 ENSSARP00000010657.1 Sorex araneus 39 5e-22 103
WERAM-Dan-0048 ENSDNOP00000004798.3 Dasypus novemcinctus 38 5e-22 103
WERAM-Anp-0078 ENSAPLP00000009547.1 Anas platyrhynchos 41 6e-22 103
WERAM-Tas-0103 ENSTSYP00000010758.1 Tarsius syrichta 42 6e-22 103
WERAM-Meg-0083 ENSMGAP00000000014.2 Meleagris gallopavo 38 7e-22 103
WERAM-Xet-0088 ENSXETP00000028569.3 Xenopus tropicalis 40 7e-22 103
WERAM-Gaga-0127 ENSGALP00000035122.2 Gallus gallus 41 8e-22 103
WERAM-Ere-0066 ENSEEUP00000005482.1 Erinaceus europaeus 37 6e-19 93.6
WERAM-Cis-0028 ENSCSAVP00000005883.1 Ciona savignyi 40 8e-19 93.2
WERAM-Cae-0070 Y119C1B.8a Caenorhabditis elegans 38 1e-18 92.4
WERAM-Cii-0085 ENSCINP00000034825.1 Ciona intestinalis 39 3e-18 91.3
Created Date 25-Jun-2016