WERAM Information

Tag Content
WERAM ID WERAM-Hos-0272
Ensembl Protein ID ENSP00000486595.1
Uniprot Accession Q8WYB5; KAT6B_HUMAN; O15087; Q86Y05; Q8WU81; Q9UKW2; Q9UKW3; Q9UKX0
Genbank Protein ID NP_001243397.1; NP_001243398.1; NP_036462.2; XP_005269721.1; XP_011547078.1
Protein Name Histone acetyltransferase KAT6B
Genbank Nucleotide ID NM_001256468.1; NM_001256469.1; NM_012330.3; XM_005269664.2; XM_011548776.1
Gene Name KAT6B;KIAA0383;MORF;MOZ2;MYST4
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSG00000281813.2 ENST00000630001.2 ENSP00000486595.1
ENSG00000281813.2 ENST00000628038.2 ENSP00000485896.1
ENSG00000281813.2 ENST00000629879.1 ENSP00000486731.1
ENSG00000281813.2 ENST00000629233.2 ENSP00000487219.1
ENSG00000281813.2 ENST00000628523.2 ENSP00000487238.1
Details
Type Family Domain Substrates AA References (PMIDs)
Ac_Reader Tandem-PHD PHD1;PHD2 H3K9; H3K14 K 22713874; 23063713
HAT MYST MYST-type HAT H3K23; H4K16 K 26208904
Status Reviewed
Classification
Type Family E-value Score Start End
HAT MYST 9.10e-127 424.3 201 989
Me_Reader PHD 1.70e-11 46.4 214 319
Ac_Reader Tandem-PHD 2.50e-40 123.8 213 272
Organism Homo sapiens
NCBI Taxa ID 9606
Functional Description
(View)		 Histone acetyltransferase which may be involved in both positive and negative regulation of transcription. Required for RUNX2-dependent transcriptional activation. May be involved in cerebral cortex development. Component of the MOZ/MORF complex which has a histone H3 acetyltransferase activity.
Domain Profile
  HAT MYST
           MYST.txt  22 spfpeelkklkklyicefclkytkskes 49 
                         p++++  +++ + ic fcl   +s+++
  ENSP00000486595.1 201 LPHEKDQPRADPIPICSFCLGTKESNRE 228
                        5778888889999*******98887654 PP
           MYST.txt   4 kniekielgkyeiktwysspfpeelkklkklyicefclkytkskeslkrhlkkCklrkpPgneiyrkdklsvfevdGkkqklycqnlCllak 95 
                        ++ ++ie+gkyei+twyssp+p+e+++l+kly+cefclky+ksk++l rh kkC +++pP+neiyr+++lsvfevdG+++k+ycqnlCllak
  ENSP00000486595.1 718 RYPSVIEFGKYEIQTWYSSPYPQEYARLPKLYLCEFCLKYMKSKNILLRHSKKCGWFHPPANEIYRRKDLSVFEVDGNMSKIYCQNLCLLAK 809
                        67889*************************************************************************************** PP
           MYST.txt  96 lfldhktlyydvepflFYvltetdekgahlvGyFskekesaekynlaCilvlPpyqrkGyGklLiefsYelsrkegkigsPekPLsdlglls 187
                        lfldhktlyydvepflFYvlt++dekg+hlvGyFskek +++kyn++Ci+++P++qr+G+G++Li+fsY+lsr+eg++gsPekPLsdlg+ls
  ENSP00000486595.1 810 LFLDHKTLYYDVEPFLFYVLTKNDEKGCHLVGYFSKEKLCQQKYNVSCIMIMPQHQRQGFGRFLIDFSYLLSRREGQAGSPEKPLSDLGRLS 901
                        ******************************************************************************************** PP
           MYST.txt 188 YrsyWkevllellkekeekkkitikelskatgiaveDivstleslnlikekkgqyillksekiveellklakskkkklkvdeeklkwkp 276
                        Y++yWk+v+le+l  ++++++i+ik++s+atg++++Di +tl++l++i++++g+++++++ek++ +++++ k+ ++ +++d+++l+w+p
  ENSP00000486595.1 902 YLAYWKSVILEYL-YHHHERHISIKAISRATGMCPHDIATTLQHLHMIDKRDGRFVIIRREKLILSHMEKLKTCSRANELDPDSLRWTP 989
                        *************.99999********************************************************************97 PP
  Me_Reader PHD
            PHD.txt   2 tiClvC.gkddegeke....mvqCdeCddwfHlkCvklp..lsslpegkswyCpsCke 52 
                        +iC +C g+++ ++++    ++ C  C    H +C+k+   l++  +   w C +Ck+
  ENSP00000486595.1 214 PICSFClGTKESNREKkpeeLLSCADCGSSGHPSCLKFCpeLTTNVKALRWQCIECKT 271
                        69****65444443334778*****************9834333333357******96 PP
            PHD.txt   3 iClvCgkddegekemvqCdeCddwfHlkCvklplsslpegkswyCpsCke 52 
                        +C +C+ ++ +++ m+ Cd+Cd+ fH++C ++pls++p+g  w+C+ C+ 
  ENSP00000486595.1 271 TCSACRVQGRNADNMLFCDSCDRGFHMECCDPPLSRMPKG-MWICQVCRP 319
                        7****888888888**************************.*******96 PP
  Ac_Reader Tandem-PHD
           PHD1.txt   1 inicdfclGtkesnkkkkPeelvscadcGrsGhPsclkftlelteavkalkWqciecksc 60 
                        i+ic+fclGtkesn++kkPeel+scadcG+sGhPsclkf++elt++vkal+Wqcieck+c
  ENSP00000486595.1 213 IPICSFCLGTKESNREKKPEELLSCADCGSSGHPSCLKFCPELTTNVKALRWQCIECKTC 272
                        69********************************************************** PP
           PHD1.txt  21 elvscadcGrsGhPsc 36 
                        +++ c  c r  h  c
  ENSP00000486595.1 284 NMLFCDSCDRGFHMEC 299
                        6778999999989888 PP
           PHD1.txt  46 avkalkWqciecks 59 
                        + + l W  iec s
  ENSP00000486595.1 698 QAQELSWEKIECES 711
                        567799******87 PP
           PHD1.txt   3 icdfclG 9  
                        +c+fcl 
  ENSP00000486595.1 750 LCEFCLK 756
                        59***95 PP
Protein Sequence
(Fasta)		MVKLANPLYT EWILEAIQKI KKQKQRPSEE RICHAVSTSH GLDKKTVSEQ LELSVQDGSV 60
LKVTNKGLAS YKDPDNPGRF SSVKPGTFPK SAKGSRGSCN DLRNVDWNKL LRRAIEGLEE 120
PNGSSLKNIE KYLRSQSDLT STTNNPAFQQ RLRLGAKRAV NNGRLLKDGP QYRVNYGSLD 180
GKGAPQYPSA FPSSLPPVSL LPHEKDQPRA DPIPICSFCL GTKESNREKK PEELLSCADC 240
GSSGHPSCLK FCPELTTNVK ALRWQCIECK TCSACRVQGR NADNMLFCDS CDRGFHMECC 300
DPPLSRMPKG MWICQVCRPK KKGRKLLHEK AAQIKRRYAK PIGRPKNKLK QRLLSVTSDE 360
GSMNAFTGRG SPGRGQKTKV CTTPSSGHAA SGKDSSSRLA VTDPTRPGAT TKITTTSTYI 420
SASTLKVNKK TKGLIDGLTK FFTPSPDGRR SRGEIIDFSK HYRPRKKVSQ KQSCTSHVLA 480
TGTTQKLKPP PSSLPPPTPI SGQSPSSQKS STATSSPSPQ SSSSQCSVPS LSSLTTNSQL 540
KALFDGLSHI YTTQGQSRKK GHPSYAPPKR MRRKTELSST AKSKAHFFGK RDIRSRFISH 600
SSSSSWGMAR GSIFKAIAHF KRTTFLKKHR MLGRLKYKVT PQMGTPSPGK GSLTDGRIKP 660
DQDDDTEIKI NIKQESADVN VIGNKDVVTE EDLDVFKQAQ ELSWEKIECE SGVEDCGRYP 720
SVIEFGKYEI QTWYSSPYPQ EYARLPKLYL CEFCLKYMKS KNILLRHSKK CGWFHPPANE 780
IYRRKDLSVF EVDGNMSKIY CQNLCLLAKL FLDHKTLYYD VEPFLFYVLT KNDEKGCHLV 840
GYFSKEKLCQ QKYNVSCIMI MPQHQRQGFG RFLIDFSYLL SRREGQAGSP EKPLSDLGRL 900
SYLAYWKSVI LEYLYHHHER HISIKAISRA TGMCPHDIAT TLQHLHMIDK RDGRFVIIRR 960
EKLILSHMEK LKTCSRANEL DPDSLRWTPI LISNAAVSEE EREAEKEAER LMEQASCWEK 1020
EEQEILSTRA NSRQSPAKVQ SKNKYLHSPE SRPVTGERGQ LLELSKESSE EEEEEEDEEE 1080
EEEEEEEEED EEEEEEEEEE EEEENIQSSP PRLTKPQSVA IKRKRPFVLK KKRGRKRRRI 1140
NSSVTTETIS ETTEVLNEPF DNSDEERPMP QLEPTCEIEV EEDGRKPVLR KAFQHQPGKK 1200
RQTEEEEGKD NHCFKNADPC RNNMNDDSSN LKEGSKDNPE PLKCKQVWPK GTKRGLSKWR 1260
QNKERKTGFK LNLYTPPETP MEPDEQVTVE EQKETSEGKT SPSPIRIEEE VKETGEALLP 1320
QEENRREETC APVSPNTSPG EKPEDDLIKP EEEEEEEEEE EEEEEEEEGE EEEGGGNVEK 1380
DPDGAKSQEK EEPEISTEKE DSARLDDHEE EEEEDEEPSH NEDHDADDED DSHMESAEVE 1440
KEELPRESFK EVLENQETFL DLNVQPGHSN PEVLMDCGVD LTASCNSEPK ELAGDPEAVP 1500
ESDEEPPPGE QAQKQDQKNS KEVDTEFKEG NPATMEIDSE TVQAVQSLTQ ESSEQDDTFQ 1560
DCAETQEACR SLQNYTRADQ SPQIATTLDD CQQSDHSSPV SSVHSHPGQS VRSVNSPSVP 1620
ALENSYAQIS PDQSAISVPS LQNMETSPMM DVPSVSDHSQ QVVDSGFSDL GSIESTTENY 1680
ENPSSYDSTM GGSICGNGSS QNSCSYSNLT SSSLTQSSCA VTQQMSNISG SCSMLQQTSI 1740
SSPPTCSVKS PQGCVVERPP SSSQQLAQCS MAANFTPPMQ LAEIPETSNA NIGLYERMGQ 1800
SDFGAGHYPQ PSATFSLAKL QQLTNTLIDH SLPYSHSAAV TSYANSASLS TPLSNTGLVQ 1860
LSQSPHSVPG GPQAQATMTP PPNLTPPPMN LPPPLLQRNM AASNIGISHS QRLQTQIASK 1920
GHISMRTKSA SLSPAAATHQ SQIYGRSQTV AMQGPARTLT MQRGMNMSVN LMPAPAYNVN 1980
SVNMNMNTLN AMNGYSMSQP MMNSGYHSNH GYMNQTPQYP MQMQMGMMGT QPYAQQPMQT 2040
PPHGNMMYTA PGHHGYMNTG MSKQSLNGSY MRR 2073
Nucleotide Sequence
(Fasta)		GACAACAACA GGGGGACACA AAATGGCGGC GGCTTAGCTC CTACCCCTGG CGGCGGCGGC 60
AGCGGTGGCG GAGGCGACGG CACCTCCTCC AGGCGGCAGC CGCAGTTTCT CAGGCAGCGG 120
CAGCGCCCCC GGCAGGCGCG GTGGCGGTGG CGCGCAGCCA GATTTGCCTG AAGACCTGGA 180
TAATCTCCAT TTTTGTCATG GACTGTTAAA ACGTTTGAAG TTCCAATTCT GGTCTTGATT 240
TCCCAGTTAA AGATGTTCTT CACCCGAATG CAGTCTTTCC TGTTGGTAAA ATAAGACAAC 300
CATCAACATT GCCTGTTTGT CTGCTTTTGA ATCTCTTAAG GATGGATGTT TGTAAGATGT 360
TGCTTAATAC AGTCTGGAAT ACTCTGTCCA TTTGTTGAAT TGTAAATGAC TTTCAAATGT 420
GCAAGTTCTG TTAAATACAA AGAGAACCTC TATGGGTAAC TTTTGTGTTG AAGAAGTCAT 480
TTGTCAACCA TGGTAAAACT TGCAAACCCA CTTTATACAG AGTGGATTCT TGAAGCTATA 540
CAGAAAATAA AAAAGCAAAA GCAAAGGCCC TCTGAAGAGA GAATCTGCCA TGCGGTCAGT 600
ACTTCCCATG GGTTGGATAA GAAGACAGTC TCTGAACAGC TGGAACTCAG TGTTCAGGAT 660
GGCTCAGTTC TCAAAGTCAC CAACAAAGGC CTTGCCTCCT ATAAGGACCC AGACAACCCT 720
GGGCGCTTTT CATCAGTTAA ACCAGGCACT TTTCCTAAGT CAGCCAAGGG GTCTAGAGGA 780
TCATGTAATG ATCTCCGCAA TGTGGATTGG AATAAACTTT TAAGGAGAGC AATTGAAGGA 840
CTTGAGGAGC CGAATGGCTC CTCCCTGAAG AACATAGAGA AGTATCTCAG AAGTCAAAGT 900
GATCTCACAA GCACCACCAA CAACCCAGCC TTTCAGCAGC GGCTGCGACT GGGGGCCAAA 960
CGCGCTGTGA ATAATGGGAG GTTACTGAAA GACGGACCGC AGTACAGGGT CAATTATGGG 1020
AGCTTAGATG GCAAAGGGGC ACCTCAGTAT CCCAGTGCAT TCCCATCCTC GCTCCCACCT 1080
GTCAGCCTTC TACCCCATGA GAAAGACCAG CCCCGTGCTG ATCCCATTCC AATATGTAGC 1140
TTCTGTTTGG GGACTAAAGA ATCAAATCGT GAAAAGAAAC CAGAAGAACT CCTCTCTTGT 1200
GCAGATTGTG GCAGTAGTGG ACACCCATCC TGTTTGAAAT TTTGTCCTGA ATTAACAACA 1260
AATGTAAAGG CCTTAAGGTG GCAGTGCATC GAATGCAAGA CATGCAGTGC CTGTAGAGTC 1320
CAAGGCAGAA ATGCTGATAA TATGCTTTTT TGTGATTCCT GTGATAGAGG ATTTCATATG 1380
GAATGCTGTG ACCCACCACT TTCCAGAATG CCAAAAGGGA TGTGGATTTG CCAAGTCTGC 1440
AGACCAAAGA AAAAGGGAAG AAAACTACTT CATGAGAAAG CTGCACAAAT AAAACGACGA 1500
TATGCAAAAC CCATTGGACG ACCGAAAAAT AAATTAAAGC AACGATTGTT GTCTGTAACC 1560
AGTGATGAAG GATCCATGAA TGCATTCACA GGAAGGGGGT CACCTGGTAG GGGTCAAAAG 1620
ACTAAAGTCT GTACCACACC TTCATCTGGT CATGCTGCAT CTGGGAAGGA CTCAAGCAGC 1680
AGATTGGCTG TTACAGACCC CACTCGGCCT GGTGCCACCA CCAAAATCAC CACCACCTCC 1740
ACCTACATTT CTGCCTCTAC ACTTAAAGTT AACAAGAAAA CCAAAGGGCT CATTGATGGC 1800
CTTACTAAGT TTTTTACACC ATCACCTGAT GGTCGCAGAT CACGAGGTGA AATTATAGAC 1860
TTTTCAAAGC ACTATCGTCC AAGGAAAAAG GTCTCTCAGA AACAGTCATG CACTTCTCAT 1920
GTGTTGGCTA CAGGTACCAC ACAAAAGCTA AAACCTCCAC CTTCTTCACT TCCACCCCCA 1980
ACCCCCATCT CCGGTCAGAG CCCCAGTTCA CAAAAGTCCA GCACGGCCAC TTCTTCTCCC 2040
TCTCCCCAGA GTTCTTCCAG CCAGTGCAGT GTGCCCTCCC TGAGCAGCCT TACCACTAAC 2100
AGCCAGCTGA AGGCACTCTT TGATGGGCTT TCTCATATCT ATACCACTCA GGGACAGTCT 2160
CGCAAAAAGG GACACCCGAG TTATGCACCA CCCAAACGTA TGCGTCGTAA AACTGAATTA 2220
TCTTCCACGG CAAAATCTAA AGCCCACTTC TTTGGCAAAA GAGATATTAG AAGTCGGTTT 2280
ATTTCTCACT CCTCCTCCTC TAGCTGGGGG ATGGCTAGAG GAAGTATTTT TAAAGCAATT 2340
GCTCACTTCA AGCGAACAAC TTTCCTTAAA AAGCACAGGA TGCTAGGCAG ATTAAAATAT 2400
AAAGTGACCC CTCAGATGGG GACCCCCTCA CCAGGGAAGG GGAGCTTGAC AGACGGAAGG 2460
ATTAAACCTG ATCAGGATGA TGATACTGAA ATAAAAATAA ACATCAAACA AGAAAGTGCA 2520
GATGTAAATG TGATTGGAAA CAAGGATGTC GTTACTGAAG AGGATTTGGA TGTTTTTAAG 2580
CAGGCCCAGG AACTTTCTTG GGAGAAAATA GAGTGTGAGA GTGGGGTGGA AGACTGTGGC 2640
CGGTACCCTT CTGTGATTGA ATTTGGTAAA TATGAAATCC AAACCTGGTA CTCCTCGCCT 2700
TACCCACAGG AATATGCAAG ATTACCAAAG CTTTACCTGT GTGAATTCTG TCTTAAATAT 2760
ATGAAAAGTA AAAATATTTT GCTAAGACAC TCCAAGAAGT GTGGATGGTT TCATCCTCCA 2820
GCAAATGAAA TTTACCGAAG GAAAGACCTT TCAGTATTTG AGGTTGATGG GAATATGAGC 2880
AAAATTTATT GCCAAAACCT TTGCTTGTTA GCCAAGCTCT TCCTGGACCA CAAAACGTTG 2940
TATTATGATG TCGAGCCATT CCTTTTTTAT GTCCTTACAA AAAATGATGA AAAGGGCTGT 3000
CATCTGGTTG GATACTTCTC TAAGGAAAAG CTTTGCCAGC AGAAGTATAA TGTCTCCTGC 3060
ATAATGATCA TGCCCCAGCA CCAAAGGCAA GGATTTGGAC GGTTTCTCAT TGATTTCAGC 3120
TATTTGCTTT CTAGAAGAGA AGGCCAAGCA GGGTCTCCTG AAAAGCCTCT CTCCGATCTG 3180
GGCCGTCTCT CCTACCTGGC ATATTGGAAG AGCGTCATCT TGGAGTATCT CTACCACCAC 3240
CATGAGAGGC ACATCAGCAT CAAGGCAATT AGCAGAGCGA CGGGCATGTG CCCACATGAC 3300
ATTGCCACCA CTCTGCAGCA CCTCCACATG ATCGACAAGA GAGATGGCAG ATTTGTCATC 3360
ATTAGACGGG AAAAGTTGAT ATTGAGCCAC ATGGAAAAGC TGAAAACCTG TTCCAGAGCC 3420
AATGAACTTG ATCCAGACAG TCTGAGGTGG ACCCCAATTT TAATTTCTAA TGCTGCAGTG 3480
TCTGAAGAAG AGCGAGAAGC TGAGAAAGAG GCTGAGCGGC TAATGGAACA AGCTAGCTGC 3540
TGGGAGAAGG AGGAACAAGA AATCCTGTCA ACTAGAGCTA ACAGTAGGCA ATCACCTGCA 3600
AAAGTACAAT CGAAAAATAA ATATTTGCAT TCCCCGGAGA GCCGGCCAGT CACAGGGGAG 3660
CGAGGGCAGC TGCTGGAGCT GTCTAAAGAG AGCAGTGAAG AAGAAGAGGA GGAGGAGGAC 3720
GAGGAGGAGG AAGAAGAGGA GGAAGAAGAG GAAGAGGATG AAGAGGAGGA AGAAGAGGAA 3780
GAAGAAGAAG AAGAAGAAGA AAATATTCAA AGCTCTCCCC CAAGATTGAC GAAACCACAG 3840
TCAGTTGCCA TAAAGAGAAA GAGGCCTTTT GTACTAAAGA AGAAAAGGGG TCGTAAACGC 3900
AGGAGGATCA ACAGCAGTGT AACAACAGAG ACCATTTCAG AGACGACAGA AGTACTGAAT 3960
GAGCCCTTTG ACAACTCAGA TGAAGAGAGG CCAATGCCAC AGCTGGAGCC TACCTGTGAG 4020
ATTGAAGTGG AGGAAGATGG CAGGAAGCCA GTCCTGAGAA AAGCATTCCA GCATCAGCCT 4080
GGGAAGAAAA GACAAACAGA GGAAGAGGAA GGAAAAGACA ATCATTGCTT CAAGAATGCT 4140
GACCCTTGTA GAAACAATAT GAATGATGAT TCAAGTAACT TGAAAGAAGG CAGTAAAGAC 4200
AATCCCGAAC CTCTAAAGTG CAAACAAGTG TGGCCAAAAG GAACAAAGCG CGGTCTATCT 4260
AAGTGGAGGC AAAACAAAGA GAGGAAGACC GGATTTAAAC TGAATTTGTA CACCCCGCCA 4320
GAAACACCCA TGGAGCCTGA CGAGCAGGTA ACAGTGGAAG AACAGAAGGA GACTTCAGAA 4380
GGAAAAACCA GCCCCAGTCC CATCAGGATT GAGGAGGAGG TCAAGGAAAC TGGGGAAGCC 4440
CTGTTGCCTC AAGAGGAAAA CAGAAGGGAA GAAACATGTG CCCCTGTAAG TCCAAACACA 4500
TCACCAGGTG AAAAACCAGA AGATGATCTC ATCAAACCTG AGGAAGAGGA AGAGGAGGAG 4560
GAGGAGGAAG AGGAAGAAGA GGAAGAAGAG GAAGGGGAAG AAGAAGAAGG AGGAGGAAAT 4620
GTAGAAAAAG ATCCAGATGG TGCTAAAAGC CAAGAAAAAG AGGAACCAGA AATCTCCACG 4680
GAAAAAGAAG ACTCTGCACG TTTGGATGAT CACGAAGAGG AGGAGGAAGA GGATGAAGAG 4740
CCATCCCACA ACGAGGACCA TGATGCCGAT GACGAGGATG ACAGCCACAT GGAGTCTGCC 4800
GAAGTGGAGA AGGAAGAGCT GCCCAGAGAA AGCTTCAAAG AAGTACTGGA AAACCAGGAG 4860
ACTTTTTTAG ACCTTAATGT GCAGCCTGGT CACTCGAACC CAGAGGTCTT AATGGACTGT 4920
GGCGTCGACC TGACAGCTTC TTGTAACAGT GAGCCCAAGG AGCTTGCTGG GGACCCTGAA 4980
GCTGTACCCG AATCTGACGA GGAGCCACCC CCAGGAGAAC AGGCACAGAA GCAGGACCAA 5040
AAGAACAGCA AGGAAGTCGA TACAGAGTTC AAAGAGGGAA ACCCAGCAAC CATGGAAATC 5100
GACTCTGAGA CTGTCCAGGC CGTTCAGTCT TTGACCCAGG AGAGCAGCGA ACAGGACGAC 5160
ACCTTTCAGG ATTGTGCCGA GACTCAAGAG GCCTGTAGAA GCCTACAGAA CTACACCCGT 5220
GCAGACCAAA GTCCACAGAT TGCCACCACG CTCGACGATT GCCAACAGTC GGACCACAGT 5280
AGCCCAGTTT CATCCGTCCA CTCCCATCCT GGCCAGTCCG TACGTTCTGT CAACAGCCCA 5340
AGTGTCCCTG CTCTGGAAAA CAGCTACGCC CAAATCAGCC CAGATCAAAG TGCCATCTCA 5400
GTGCCATCTC TGCAGAACAT GGAAACCAGT CCCATGATGG ATGTCCCATC AGTTTCAGAT 5460
CATTCACAGC AAGTCGTAGA CAGTGGATTT AGTGACCTGG GCAGTATCGA GAGCACAACT 5520
GAGAACTACG AAAACCCAAG CAGCTACGAT TCTACTATGG GAGGCAGCAT CTGTGGAAAC 5580
GGCTCTTCAC AGAACAGCTG CTCCTATAGC AACCTCACCT CCAGCAGTCT GACACAGAGC 5640
AGCTGTGCTG TCACCCAGCA GATGTCCAAC ATCAGCGGGA GCTGCAGCAT GCTGCAGCAA 5700
ACCAGCATCA GCTCCCCTCC GACCTGCAGC GTCAAGTCTC CTCAAGGCTG TGTGGTGGAG 5760
AGGCCTCCGA GCAGCAGCCA GCAGCTGGCT CAGTGCAGCA TGGCTGCTAA CTTCACCCCA 5820
CCCATGCAGC TGGCTGAAAT CCCCGAGACG AGCAACGCCA ACATTGGCTT ATACGAGCGA 5880
ATGGGTCAGA GTGATTTTGG GGCTGGGCAT TACCCGCAGC CGTCAGCCAC CTTCAGCCTT 5940
GCCAAACTGC AGCAGTTAAC TAATACACTT ATTGATCATT CATTGCCTTA CAGCCATTCC 6000
GCTGCTGTGA CTTCCTATGC AAACAGTGCC TCTTTGTCCA CACCATTAAG TAACACAGGG 6060
CTTGTTCAAC TTTCTCAGTC TCCACACTCC GTCCCTGGGG GACCCCAAGC ACAAGCTACC 6120
ATGACCCCAC CCCCCAACCT GACTCCTCCT CCAATGAATC TGCCGCCGCC TCTTTTGCAA 6180
CGGAACATGG CTGCATCAAA TATTGGCATC TCTCACAGCC AAAGACTGCA AACCCAGATT 6240
GCCAGCAAGG GCCACATCTC CATGAGAACC AAGTCAGCGT CTCTGTCACC AGCCGCTGCC 6300
ACCCATCAGT CACAAATCTA TGGGCGCTCC CAGACTGTAG CCATGCAGGG TCCTGCACGG 6360
ACTTTAACGA TGCAAAGAGG CATGAACATG AGTGTGAACC TGATGCCAGC GCCAGCCTAC 6420
AATGTCAACT CTGTGAACAT GAACATGAAC ACTCTCAACG CCATGAATGG GTACAGCATG 6480
TCCCAGCCAA TGATGAACAG TGGCTACCAC AGCAATCATG GCTATATGAA TCAAACGCCC 6540
CAATACCCTA TGCAGATGCA GATGGGCATG ATGGGCACCC AGCCATATGC CCAGCAGCCA 6600
ATGCAGACCC CACCCCACGG TAACATGATG TACACGGCCC CCGGACATCA CGGCTACATG 6660
AACACAGGCA TGTCCAAACA GTCTCTCAAT GGCTCCTACA TGAGAAGGTA GACAACGTGG 6720
GCAGTCCACA AAACCTACGG GGCATCACTA TTGGATTGAT CTGCACAAAT ACCTTTGAAG 6780
AGTACGATTT CAAAACCAGC AATTGGTGTG AATGCAAAAA CATTTGTTGG CACCATTTAT 6840
TTAAAAAAAA AAAAAGCTGT ATGCAGCAGA AAGCCTTATA CAAGTTGTTT TTCTTTTTTT 6900
CCTTTTTCTT TTTTTTGGTA CCTTCATTTC TGTTACTTTT ATATAAAATT CTCTGCAAAG 6960
GAAGGCCTCT CTTTGGACTA CAATTTGGAG GCAGCCACTT GTTGTGCCTG CTTCTGTTAA 7020
ACAATGTGGA TATCAAGCCC CCCCAAATTA TCTGTTTTAA TATTGAACCT AGAGCTTTTT 7080
TTTTCCCTTC CCTGTCCACT CCATGTAAAT GCCTTTAGCA TTTCAGTTAT TGTATATTTT 7140
GTTTAAGGTG ACACTTCAGC ATGCCGCTAA TGTCTTTGTT AGTGACAGTG CATTTTGTAG 7200
TACTGTACAA GTGTTGTGCT AACAGTAAGC CATTTCTTAA GTTTTTTGCC TTGATTAGGG 7260
TGCCCTAATT TGAGGGTTTT AAAAAAAACT ATATTTTTGT TAATTATAAA ACTGTAAAGA 7320
GCTATAAAAG CTATTCCCAT TTGGTTAGTC AAAAGGGTTT TATTGCTAAA TGTTTGGTGT 7380
AAAGTTGAGA CCCTTTTCCA TTTTGGTGAC AGATTTCTTT GGGGAAAAAA GGCAGCTTTC 7440
TGTTTTATAA ATGCAGACTT CTGTTTATTG AATGAAGCAT ATCTCAGTGT TTATCTGTCA 7500
GGTTTTGAAA CATTTCATAT ATGTCCAAAT ACTTGGCAGG ATTTAAAAAA AAATAGTGAA 7560
TTTGGTGTAA AGTTGCTATT TTATGGAAAT GCCTCTAACT TTACATTTTC ATTCCATCTG 7620
TAGATTTTTC TATCTTTATA AAATATTGGA GTTATTTTTT AAGGAAAAAT AGAAAAGTAG 7680
CTTGTGAATA GCTCAAACTA AGCTTACAAA TCGCATGTAA AAAAGCAAAA AAGTTATTTG 7740
TGTCTGTTTA TATTGCTTCC TTTTTTGTAG CCTTTGTACC TGTACAGGGT GACAGTAAGG 7800
GCCAAGCAGG AGAGGCGTAA TCCTTGTATA AAATAGGATC CAGCGACACT CTTGTATTTA 7860
TCTGTTCTCT TTTTAGTCAG TCACTTCAAA AAAACAAAAA ACAAACAAAA AAAAGCTGTA 7920
CATTTTAACA TAAAATAAAT TATGATGAGC CATTTTTAGC CTCTTGTGTC CTGTCATATT 7980
ATGATTGATA GAGAATGACC AATGGAACTG TATCATGTGT CACGCCTCAG AACACATACA 8040
CATTTTGGGA AAATAAATTA TTTAGTGTAA ATTGGAGTTA TGGGATTTTC TGATTTGTTT 8100
TGACTTTGGG GGAGGGGTTG GCAATAAATA AGAGTAATAT CTAATAAAAC CATCACATAT 8160
ACCAAATACC TATTTAATAA ATTAATTTAT AATGGATTTT AATGCTTTTC ATGAAAGTTT 8220
ATTTTATGCG AGTGCATACC TTCTGTATGC CAATCATTGT CTTTAAAATA AAGTGAAATT 8280
GTTTTTT 8288
Sequence Source Ensembl
Keyword

KW-0007--Acetylation
KW-0010--Activator
KW-0012--Acyltransferase
KW-0025--Alternative splicing
KW-0156--Chromatin regulator
KW-0160--Chromosomal rearrangement
KW-0181--Complete proteome
KW-1017--Isopeptide bond
KW-0479--Metal-binding
KW-0539--Nucleus
KW-0621--Polymorphism
KW-1185--Reference proteome
KW-0677--Repeat
KW-0678--Repressor
KW-0804--Transcription
KW-0805--Transcription regulation
KW-0808--Transferase
KW-0832--Ubl conjugation
KW-0862--Zinc
KW-0863--Zinc-finger
--
Interpro

IPR016181--Acyl_CoA_acyltransferase
IPR002717--HAT_MYST-type
IPR005818--Histone_H1/H5_H15
IPR011991--WHTH_DNA-bd_dom
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD
PROSITE

PS51504--H15
PS51726--MYST_HAT
PS01359--ZF_PHD_1
PS50016--ZF_PHD_2
Pfam

PF01853--MOZ_SAS
PF00628--PHD
Gene Ontology

GO:0070776--C:MOZ/MORF histone acetyltransferase complex
GO:0005654--C:nucleoplasm
GO:0000786--C:nucleosome
GO:0005634--C:nucleus
GO:0016407--F:acetyltransferase activity
GO:0003677--F:DNA binding
GO:0004402--F:histone acetyltransferase activity
GO:0008134--F:transcription factor binding
GO:0008270--F:zinc ion binding
GO:0016573--P:histone acetylation
GO:0043966--P:histone H3 acetylation
GO:0045892--P:negative regulation of transcription, DNA-templated
GO:0006334--P:nucleosome assembly
GO:0045944--P:positive regulation of transcription from RNA polymerase II promoter
GO:0045893--P:positive regulation of transcription, DNA-templated
GO:0006355--P:regulation of transcription, DNA-templated
GO:0006351--P:transcription, DNA-templated
Orthology
WERAM ID Ensembl Protein ID Species Identity E-value Score
WERAM-Gog-0099 ENSGGOP00000008565.2 Gorilla gorilla 99 0.0 3486
WERAM-Pat-0021 ENSPTRP00000004608.5 Pan troglodytes 99 0.0 3484
WERAM-Chs-0110 ENSCSAP00000005308.1 Chlorocebus sabaeus 99 0.0 3474
WERAM-Paa-0171 ENSPANP00000020274.1 Papio anubis 96 0.0 3418
WERAM-Caj-0010 ENSCJAP00000002250.2 Callithrix jacchus 94 0.0 3326
WERAM-Eqc-0081 ENSECAP00000010370.1 Equus caballus 95 0.0 3320
WERAM-Dan-0056 ENSDNOP00000017553.2 Dasypus novemcinctus 95 0.0 3320
WERAM-Aim-0026 ENSAMEP00000001875.1 Ailuropoda melanoleuca 94 0.0 3314
WERAM-Mup-0033 ENSMPUP00000003295.1 Mustela putorius furo 94 0.0 3301
WERAM-Fec-0057 ENSFCAP00000005151.3 Felis catus 94 0.0 3285
WERAM-Sus-0074 ENSSSCP00000011001.2 Sus scrofa 94 0.0 3268
WERAM-Otg-0164 ENSOGAP00000013816.2 Otolemur garnettii 94 0.0 3266
WERAM-Ova-0090 ENSOARP00000009313.1 Ovis aries 93 0.0 3261
WERAM-Caf-0158 ENSCAFP00000022633.4 Canis familiaris 94 0.0 3260
WERAM-Myl-0085 ENSMLUP00000006798.2 Myotis lucifugus 93 0.0 3221
WERAM-Ptv-0099 ENSPVAP00000009046.1 Pteropus vampyrus 93 0.0 3205
WERAM-Ect-0112 ENSETEP00000012551.1 Echinops telfairi 87 0.0 2951
WERAM-Tag-0100 ENSTGUP00000006836.1 Taeniopygia guttata 80 0.0 2808
WERAM-Mim-0001 ENSMICP00000000022.1 Microcebus murinus 92 0.0 2771
WERAM-Tut-0005 ENSTTRP00000000341.1 Tursiops truncatus 89 0.0 2447
WERAM-Poa-0023 ENSPPYP00000002692.2 Pongo abelii 96 0.0 2308
WERAM-Nol-0185 ENSNLEP00000020448.2 Nomascus leucogenys 99 0.0 2302
WERAM-Mam-0215 ENSMMUP00000030925.2 Macaca mulatta 98 0.0 2266
WERAM-Dio-0052 ENSDORP00000005019.1 Dipodomys ordii 95 0.0 2249
WERAM-Prc-0040 ENSPCAP00000003620.1 Procavia capensis 95 0.0 2205
WERAM-Ict-0096 ENSSTOP00000010025.2 Ictidomys tridecemlineatus 94 0.0 2175
WERAM-Bot-0036 ENSBTAP00000003798.4 Bos taurus 91 0.0 2160
WERAM-Cap-0082 ENSCPOP00000005892.2 Cavia porcellus 84 0.0 2123
WERAM-Orc-0167 ENSOCUP00000014911.3 Oryctolagus cuniculus 93 0.0 2114
WERAM-Tas-0059 ENSTSYP00000005370.1 Tarsius syrichta 98 0.0 2084
WERAM-Anp-0093 ENSAPLP00000010721.1 Anas platyrhynchos 83 0.0 2049
WERAM-Mum-0039 ENSMUSP00000066693.7 Mus musculus 88 0.0 2045
WERAM-Vip-0080 ENSVPAP00000007479.1 Vicugna pacos 91 0.0 1995
WERAM-Mod-0005 ENSMODP00000000887.5 Monodelphis domestica 80 0.0 1840
WERAM-Tub-0087 ENSTBEP00000010059.1 Tupaia belangeri 90 0.0 1790
WERAM-Soa-0082 ENSSARP00000007754.1 Sorex araneus 95 0.0 1570
WERAM-Lac-0049 ENSLACP00000007072.1 Latimeria chalumnae 74 0.0 1415
WERAM-Tar-0157 ENSTRUP00000034035.1 Takifugu rubripes 60 0.0 1409
WERAM-Gaa-0019 ENSGACP00000002833.1 Gasterosteus aculeatus 59 0.0 1377
WERAM-Leo-0031 ENSLOCP00000005426.1 Lepisosteus oculatus 62 0.0 1339
WERAM-Xim-0193 ENSXMAP00000015562.1 Xiphophorus maculatus 68 0.0 1329
WERAM-Pof-0099 ENSPFOP00000008973.2 Poecilia formosa 67 0.0 1328
WERAM-Ere-0048 ENSEEUP00000004233.1 Erinaceus europaeus 85 0.0 1259
WERAM-Asm-0039 ENSAMXP00000004916.1 Astyanax mexicanus 65 0.0 1256
WERAM-Loa-0143 ENSLAFP00000012865.3 Loxodonta africana 81 0.0 1170
WERAM-Chh-0001 ENSCHOP00000000101.1 Choloepus hoffmanni 85 0.0 1144
WERAM-Ora-0060 ENSOANP00000009404.2 Ornithorhynchus anatinus 78 0.0 1062
WERAM-Sah-0096 ENSSHAP00000011021.1 Sarcophilus harrisii 82 0.0 1011
WERAM-Mae-0012 ENSMEUP00000001058.1 Macropus eugenii 86 0.0 974
WERAM-Pes-0160 ENSPSIP00000019128.1 Pelodiscus sinensis 73 0.0 968
WERAM-Gaga-0054 ENSGALP00000008060.4 Gallus gallus 71 0.0 952
WERAM-Fia-0090 ENSFALP00000007269.1 Ficedula albicollis 70 0.0 944
WERAM-Ran-0083 ENSRNOP00000064386.2 Rattus norvegicus 82 0.0 917
WERAM-Anc-0090 ENSACAP00000008638.3 Anolis carolinensis 67 0.0 841
WERAM-Meg-0067 ENSMGAP00000006085.2 Meleagris gallopavo 77 0.0 738
WERAM-Dar-0112 ENSDARP00000072241.3 Danio rerio 67 0.0 653
WERAM-Orn-0196 ENSONIP00000020390.1 Oreochromis niloticus 56 0.0 653
WERAM-Ten-0162 ENSTNIP00000006152.1 Tetraodon nigroviridis 68 0.0 651
WERAM-Orla-0087 ENSORLP00000010755.1 Oryzias latipes 70 0.0 644
WERAM-Gam-0003 ENSGMOP00000000211.1 Gadus morhua 66 0.0 641
WERAM-Ocp-0127 ENSOPRP00000013509.1 Ochotona princeps 64 5e-168 590
WERAM-Drm-0054 FBpp0072159 Drosophila melanogaster 64 5e-109 394
WERAM-Xet-0138 ENSXETP00000047416.3 Xenopus tropicalis 55 1e-101 370
WERAM-Pem-0064 ENSPMAP00000007030.1 Petromyzon marinus 55 2e-100 365
WERAM-Cii-0017 ENSCINP00000006517.3 Ciona intestinalis 55 3e-97 355
WERAM-Cis-0023 ENSCSAVP00000005035.1 Ciona savignyi 49 4e-97 354
WERAM-Aso-0012 CADAORAP00001649 Aspergillus oryzae 49 2e-83 309
WERAM-Zem-0080 GRMZM2G140288_P01 Zea mays 56 2e-83 309
WERAM-Orl-0045 KN538920.1_FGP012 Oryza longistaminata 56 2e-83 309
WERAM-Ast-0034 CADATEAP00009194 Aspergillus terreus 48 2e-83 309
WERAM-Asf-0007 CADAFLAP00002066 Aspergillus flavus 49 3e-83 308
WERAM-Art-0119 AT5G09740.1 Arabidopsis thaliana 55 4e-83 308
WERAM-Orbr-0089 OB07G28490.1 Oryza brachyantha 56 5e-83 308
WERAM-Asc-0022 CADACLAP00004828 Aspergillus clavatus 48 7e-83 307
WERAM-Orp-0078 OPUNC07G21500.1 Oryza punctata 56 1e-82 306
WERAM-Glm-0035 GLYMA04G16180.1 Glycine max 55 1e-82 306
WERAM-Ors-0074 OS07T0626600-01 Oryza sativa 56 1e-82 306
WERAM-Orr-0084 ORUFI07G24020.1 Oryza rufipogon 56 1e-82 306
WERAM-Orni-0080 ONIVA07G22490.1 Oryza nivara 56 1e-82 306
WERAM-Orm-0076 OMERI07G19290.1 Oryza meridionalis 56 1e-82 306
WERAM-Ori-0077 BGIOSGA023877-PA Oryza indica 56 2e-82 306
WERAM-Thc-0095 EOY16150 Theobroma cacao 55 2e-82 306
WERAM-Pot-0027 POPTR_0002s09010.1 Populus trichocarpa 55 2e-82 306
WERAM-Asfu-0035 CADAFUAP00007935 Aspergillus fumigatus 48 2e-82 306
WERAM-Orgl-0078 OGLUM07G22920.1 Oryza glumaepatula 56 2e-82 305
WERAM-Mua-0086 GSMUA_Achr6P10570_001 Musa acuminata 56 3e-82 305
WERAM-Lep-0080 LPERR07G19900.1 Leersia perrieri 56 3e-82 305
WERAM-Asni-0011 CADANGAP00004195 Aspergillus niger 52 4e-82 305
WERAM-Met-0059 AES68391 Medicago truncatula 55 4e-82 305
WERAM-Org-0080 ORGLA07G0178500.1 Oryza glaberrima 56 4e-82 305
WERAM-Viv-0113 VIT_18s0001g04100.t01 Vitis vinifera 55 5e-82 305
WERAM-Sol-0133 Solyc11g013520.1.1 Solanum lycopersicum 54 5e-82 305
WERAM-Arl-0101 fgenesh2_kg.6__ 927__ AT5G09740.1 Arabidopsis lyrata 54 5e-82 305
WERAM-Sob-0038 Sb02g039960.1 Sorghum bicolor 56 6e-82 304
WERAM-Asn-0016 CADANIAP00003430 Aspergillus nidulans 51 6e-82 304
WERAM-Brr-0045 Bra009399.1-P Brassica rapa 54 6e-82 304
WERAM-Bro-0183 Bo9g173870.1 Brassica oleracea 54 7e-82 304
WERAM-Orb-0081 OBART07G22890.1 Oryza barthii 56 7e-82 304
WERAM-Prp-0062 EMJ23350 Prunus persica 54 9e-82 303
WERAM-Php-0014 PP1S13_111V6.1 Physcomitrella patens 54 9e-82 303
WERAM-Amt-0019 ERM94321 Amborella trichopoda 54 1e-81 303
WERAM-Nec-0023 EFNCRP00000004537 Neurospora crassa 51 2e-81 303
WERAM-Brd-0008 BRADI1G20770.1 Brachypodium distachyon 55 2e-81 303
WERAM-Scs-0002 EDN90912 Sclerotinia sclerotiorum 50 2e-81 302
WERAM-Sei-0114 Si029855m Setaria italica 55 3e-81 302
WERAM-Fuo-0033 FOXG_11372P0 Fusarium oxysporum 51 7e-81 301
WERAM-Tra-0098 Traes_2DS_DCFDFA58B.2 Triticum aestivum 55 7e-81 301
WERAM-Aet-0100 EMT32375 Aegilops tauschii 55 7e-81 301
WERAM-Lem-0040 CBX94397 Leptosphaeria maculans 51 7e-81 300
WERAM-Mao-0013 MGG_04615T0 Magnaporthe oryzae 52 9e-81 300
WERAM-Tru-0098 TRIUR3_34388-P1 Triticum urartu 55 9e-81 300
WERAM-Map-0029 MAPG_08226T0 Magnaporthe poae 51 1e-80 300
WERAM-Yal-0001 CAG83662 Yarrowia lipolytica 50 2e-80 299
WERAM-Gag-0004 GGTG_01203T0 Gaeumannomyces graminis 51 2e-80 299
WERAM-Sem-0015 EFJ14590 Selaginella moellendorffii 53 2e-80 299
Created Date 25-Jun-2016