| Tag |
Content |
| WERAM ID |
WERAM-Art-0119 |
| Ensembl Protein ID |
AT5G09740.1 |
| Uniprot Accession |
Q9LXD7; MYST2_ARATH; C0SVP1; F4KE11; Q8GZ97; Q8LCD4
|
| Genbank Protein ID |
NP_001078558.1; NP_196536.1
|
| Protein Name |
Histone acetyltransferase of the MYST family 2 |
| Genbank Nucleotide ID |
NM_001085089.1; NM_121011.3
|
| Gene Name |
HAM2;MYST2;HAG5;At5g09740;F17I14.70;MTH16.20 |
| Ensembl Information |
|
| Details |
| Type |
Family |
Domain |
Substrates |
AA |
References (PMIDs) |
| HAT |
MYST |
MYST-type HAT |
H4K5 |
K |
24653661; 16648464
|
|
| Status |
Reviewed |
| Classification |
| Type |
Family |
E-value |
Score |
Start |
End |
| HAT |
MYST |
1.00e-126 |
422.6 |
170 |
440 |
|
| Organism |
Arabidopsis thaliana |
| NCBI Taxa ID |
3702 |
Functional Description
(View)Functional Description
Histone acetyltransferase which may be involved in transcriptional activation. Acetylates 'Lys-5' of histone H4 (H4K5ac) (PubMed:16648464, PubMed:17877703). Essential for gametophyte development (PubMed:19040736). Negative regulator of flowering controlling the H4K5ac levels in the FLC chromatin (PubMed:23273925). |
Histone acetyltransferase which may be involved in transcriptional activation. Acetylates 'Lys-5' of histone H4 (H4K5ac) (PubMed:16648464, PubMed:17877703). Essential for gametophyte development (PubMed:19040736). Negative regulator of flowering controlling the H4K5ac levels in the FLC chromatin (PubMed:23273925).
|
| Domain Profile |
HAT MYST
MYST.txt 2 kvkniekielgkyeiktwysspfpeelkklkklyicefclkytkskeslkrhlkkCklrkpPgneiyrkdklsvfevdGkkqklycqnlCllaklfld 99
kvkni++ielgkyei+twy+spfp+e++++ kl++cefcl+++k+ke+l+rh++kC+l++pPg+eiyr+++ls+fevdGkk+k+y+qnlC+laklfld
AT5G09740.1 170 KVKNISTIELGKYEIETWYFSPFPPEYNDCVKLFFCEFCLNFMKRKEQLQRHMRKCDLKHPPGDEIYRSGTLSMFEVDGKKNKVYAQNLCYLAKLFLD 267
799*********************************************************************************************** PP
MYST.txt 100 hktlyydvepflFYvltetdekgahlvGyFskekesaekynlaCilvlPpyqrkGyGklLiefsYelsrkegkigsPekPLsdlgllsYrsyWkevll 197
hktlyydv+ flFYvl+e+d++g+h+vGyFskek+s+e+ynlaCil+lP yqrkGyGk+Li+fsYels+kegk+g+Pe+PLsdlgllsYr yW++vll
AT5G09740.1 268 HKTLYYDVDLFLFYVLCECDDRGCHMVGYFSKEKHSEEAYNLACILTLPSYQRKGYGKFLIAFSYELSKKEGKVGTPERPLSDLGLLSYRGYWTRVLL 365
************************************************************************************************** PP
MYST.txt 198 ellkekeekkkitikelskatgiaveDivstleslnlikekkgqyillksekiveellklakskkkklkvdeeklkwkp 276
e+l k++k +i+ikels++t+i++eDi+stl+sl+li+++kgq++++++ k+++++lk+a + l+vd +kl w+p
AT5G09740.1 366 EIL--KKHKGNISIKELSDVTAIKAEDILSTLQSLELIQYRKGQHVICADPKVLDRHLKAAG--RGGLDVDASKLIWTP 440
***..89999***********************************************88887..899**********97 PP
|
Protein Sequence
(Fasta) | MGSSANTETN GNAPPPSSNQ KPPATNGVDG SHPPPPPLTP DQAIIESDPS KKRKMGMLPL 60
EVGTRVMCRW RDGKHHPVKV IERRRIHNGG QNDYEYYVHY TEFNRRLDEW TQLDQLDLDS 120
VECAVDEKVE DKVTSLKMTR HQKRKIDETH IEGHEELDAA SLREHEEFTK VKNISTIELG 180
KYEIETWYFS PFPPEYNDCV KLFFCEFCLN FMKRKEQLQR HMRKCDLKHP PGDEIYRSGT 240
LSMFEVDGKK NKVYAQNLCY LAKLFLDHKT LYYDVDLFLF YVLCECDDRG CHMVGYFSKE 300
KHSEEAYNLA CILTLPSYQR KGYGKFLIAF SYELSKKEGK VGTPERPLSD LGLLSYRGYW 360
TRVLLEILKK HKGNISIKEL SDVTAIKAED ILSTLQSLEL IQYRKGQHVI CADPKVLDRH 420
LKAAGRGGLD VDASKLIWTP YKDQS 445Protein Fasta Sequence
>AT5G09740.1|HAM2;MYST2;HAG5;At5g09740;F17I14.70;MTH16.20|Arabidopsis thaliana
MGSSANTETNGNAPPPSSNQKPPATNGVDGSHPPPPPLTPDQAIIESDPSKKRKMGMLPLEVGTRVMCRWRDGKHHPVKVIERRRIHNGGQNDYEYYVHYTEFNRRLDEWTQLDQLDLDSVECAVDEKVEDKVTSLKMTRHQKRKIDETHIEGHEELDAASLREHEEFTKVKNISTIELGKYEIETWYFSPFPPEYNDCVKLFFCEFCLNFMKRKEQLQRHMRKCDLKHPPGDEIYRSGTLSMFEVDGKKNKVYAQNLCYLAKLFLDHKTLYYDVDLFLFYVLCECDDRGCHMVGYFSKEKHSEEAYNLACILTLPSYQRKGYGKFLIAFSYELSKKEGKVGTPERPLSDLGLLSYRGYWTRVLLEILKKHKGNISIKELSDVTAIKAEDILSTLQSLELIQYRKGQHVICADPKVLDRHLKAAGRGGLDVDASKLIWTPYKDQS |
Nucleotide Sequence
(Fasta) | TATGAGAAAG AAAGCCCACC CGGGAATCTC CGACCCGACC GAGAAATGGG ATCGTCAGCG 60
AATACAGAAA CCAACGGCAA CGCACCGCCA CCGTCGTCGA ATCAAAAGCC TCCGGCTACG 120
AACGGCGTTG ATGGGTCTCA TCCTCCTCCT CCTCCTTTAA CTCCTGATCA AGCTATTATA 180
GAGTCGGATC CGTCGAAGAA GAGGAAAATG GGGATGCTTC CTCTAGAAGT GGGTACTCGT 240
GTGATGTGTC GGTGGAGAGA CGGGAAACAC CATCCGGTGA AAGTAATTGA GCGCCGGCGG 300
ATACATAACG GCGGTCAAAA TGATTACGAG TATTACGTTC ATTACACTGA GTTTAATAGG 360
AGGCTGGATG AATGGACTCA GCTGGACCAA CTGGACCTTG ATTCAGTAGA GTGCGCTGTA 420
GATGAAAAAG TGGAAGACAA GGTAACAAGC TTGAAGATGA CACGTCACCA GAAGAGGAAG 480
ATCGATGAGA CACATATAGA GGGTCATGAA GAGCTGGATG CAGCAAGTTT GCGTGAACAT 540
GAAGAGTTCA CGAAAGTGAA GAACATATCA ACAATTGAGC TTGGAAAATA TGAGATTGAG 600
ACTTGGTACT TCTCCCCTTT TCCGCCAGAA TACAATGACT GTGTGAAGCT CTTTTTTTGT 660
GAGTTTTGCC TGAACTTCAT GAAACGCAAA GAGCAGCTTC AAAGGCATAT GAGGAAGTGT 720
GACCTGAAGC ACCCACCTGG TGATGAAATT TACCGAAGTG GTACCTTGTC AATGTTTGAG 780
GTAGATGGCA AAAAGAACAA GGTTTATGCA CAGAATCTCT GCTACCTGGC AAAGTTATTT 840
CTTGACCACA AAACTCTTTA CTACGATGTT GATTTGTTTC TATTCTACGT TCTTTGCGAA 900
TGTGATGACC GAGGATGCCA CATGGTTGGG TACTTTTCAA AGGAGAAGCA TTCGGAAGAA 960
GCATACAACT TAGCTTGCAT TCTAACCCTG CCTTCATATC AAAGAAAAGG CTATGGAAAG 1020
TTCTTAATAG CCTTTTCCTA TGAACTGTCA AAGAAAGAGG GAAAAGTTGG GACACCGGAA 1080
AGACCCTTGT CGGATCTAGG CTTACTAAGC TACAGAGGTT ATTGGACTCG TGTTCTATTA 1140
GAAATCTTGA AAAAACATAA GGGAAACATT TCTATCAAGG AGCTGAGCGA CGTGACAGCA 1200
ATCAAAGCGG AAGATATATT AAGCACACTT CAGAGCCTAG AACTGATACA GTACAGGAAA 1260
GGACAGCATG TGATCTGTGC GGATCCAAAG GTTCTGGACC GACATCTGAA AGCTGCAGGC 1320
CGAGGTGGTC TTGATGTAGA TGCTAGCAAA CTGATTTGGA CACCTTACAA GGACCAGAGT 1380
TAAGAGTAAG TACACTCCTC TTGTGCCATT GGATTTGATT TGAGTGTGTA AGTAAAGCGG 1440
GCTGTCTTAT TCTCCTGAAA TGTAAGTGTA CTTTACTTGT AAATGTTGAA ATCGTACTTG 1500
GAATGGTGTT TGTTTACAAC TCTTATAATG AGGAAATTTG AAGCAATTTC ATAGGTCCAT 1560
CTTTCTTTTG CT
1573Nucleotide Fasta Sequence
>AT5G09740.1|MYST|Arabidopsis thaliana
TATGAGAAAGAAAGCCCACCCGGGAATCTCCGACCCGACCGAGAAATGGGATCGTCAGCGAATACAGAAACCAACGGCAACGCACCGCCACCGTCGTCGAATCAAAAGCCTCCGGCTACGAACGGCGTTGATGGGTCTCATCCTCCTCCTCCTCCTTTAACTCCTGATCAAGCTATTATAGAGTCGGATCCGTCGAAGAAGAGGAAAATGGGGATGCTTCCTCTAGAAGTGGGTACTCGTGTGATGTGTCGGTGGAGAGACGGGAAACACCATCCGGTGAAAGTAATTGAGCGCCGGCGGATACATAACGGCGGTCAAAATGATTACGAGTATTACGTTCATTACACTGAGTTTAATAGGAGGCTGGATGAATGGACTCAGCTGGACCAACTGGACCTTGATTCAGTAGAGTGCGCTGTAGATGAAAAAGTGGAAGACAAGGTAACAAGCTTGAAGATGACACGTCACCAGAAGAGGAAGATCGATGAGACACATATAGAGGGTCATGAAGAGCTGGATGCAGCAAGTTTGCGTGAACATGAAGAGTTCACGAAAGTGAAGAACATATCAACAATTGAGCTTGGAAAATATGAGATTGAGACTTGGTACTTCTCCCCTTTTCCGCCAGAATACAATGACTGTGTGAAGCTCTTTTTTTGTGAGTTTTGCCTGAACTTCATGAAACGCAAAGAGCAGCTTCAAAGGCATATGAGGAAGTGTGACCTGAAGCACCCACCTGGTGATGAAATTTACCGAAGTGGTACCTTGTCAATGTTTGAGGTAGATGGCAAAAAGAACAAGGTTTATGCACAGAATCTCTGCTACCTGGCAAAGTTATTTCTTGACCACAAAACTCTTTACTACGATGTTGATTTGTTTCTATTCTACGTTCTTTGCGAATGTGATGACCGAGGATGCCACATGGTTGGGTACTTTTCAAAGGAGAAGCATTCGGAAGAAGCATACAACTTAGCTTGCATTCTAACCCTGCCTTCATATCAAAGAAAAGGCTATGGAAAGTTCTTAATAGCCTTTTCCTATGAACTGTCAAAGAAAGAGGGAAAAGTTGGGACACCGGAAAGACCCTTGTCGGATCTAGGCTTACTAAGCTACAGAGGTTATTGGACTCGTGTTCTATTAGAAATCTTGAAAAAACATAAGGGAAACATTTCTATCAAGGAGCTGAGCGACGTGACAGCAATCAAAGCGGAAGATATATTAAGCACACTTCAGAGCCTAGAACTGATACAGTACAGGAAAGGACAGCATGTGATCTGTGCGGATCCAAAGGTTCTGGACCGACATCTGAAAGCTGCAGGCCGAGGTGGTCTTGATGTAGATGCTAGCAAACTGATTTGGACACCTTACAAGGACCAGAGTTAAGAGTAAGTACACTCCTCTTGTGCCATTGGATTTGATTTGAGTGTGTAAGTAAAGCGGGCTGTCTTATTCTCCTGAAATGTAAGTGTACTTTACTTGTAAATGTTGAAATCGTACTTGGAATGGTGTTTGTTTACAACTCTTATAATGAGGAAATTTGAAGCAATTTCATAGGTCCATCTTTCTTTTGCT
|
| Sequence Source |
Ensembl |
| Keyword |
KW-0007--Acetylation
KW-0010--Activator
KW-0012--Acyltransferase
KW-0025--Alternative splicing
KW-0156--Chromatin regulator
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0804--Transcription
KW-0805--Transcription regulation
KW-0808--Transferase
KW-0862--Zinc
KW-0863--Zinc-finger
--
|
| Interpro |
IPR016181--Acyl_CoA_acyltransferase
IPR000953--Chromo/shadow_dom
IPR016197--Chromodomain-like
IPR002717--HAT_MYST-type
IPR025995--Tudor-knot
|
| PROSITE |
PS51726--MYST_HAT
|
| Pfam |
PF01853--MOZ_SAS
PF11717--Tudor-knot
|
| Gene Ontology |
GO:0005634--C:nucleus
GO:0004402--F:histone acetyltransferase activity
GO:0046872--F:metal ion binding
GO:0006281--P:DNA repair
GO:0016573--P:histone acetylation
GO:0006355--P:regulation of transcription, DNA-templated
GO:0010224--P:response to UV-B
GO:0006351--P:transcription, DNA-templated
|
| Orthology |
|
| Created Date |
25-Jun-2016 |
