WERAM Information


Tag Content
WERAM ID WERAM-Mum-0039
Ensembl Protein ID ENSMUSP00000066693.7
Uniprot Accession Q8BRB7; KAT6B_MOUSE; E9QK86; Q7TNW5; Q8BG35; Q8C441; Q9JKX5
Genbank Protein ID NP_059507.2; XP_006519331.1; XP_011243418.1
Protein Name Histone acetyltransferase KAT6B
Genbank Nucleotide ID NM_017479.3; XM_006519268.2; XM_011245116.1
Gene Name KAT6B;Myst4;Morf
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSMUSG00000021767.16 ENSMUST00000069648.13 ENSMUSP00000066693.7
ENSMUSG00000021767.16 ENSMUST00000182405.7 ENSMUSP00000138377.1
ENSMUSG00000021767.16 ENSMUST00000182964.1 ENSMUSP00000138421.1
ENSMUSG00000021767.16 ENSMUST00000182855.7 ENSMUSP00000138511.1
Details
Type Family Domain Substrates AA References (PMIDs)
HAT MYST MYST-type HAT K 25568313
Status Reviewed
Classification
Type Family E-value Score Start End
HAT MYST 6.70e-127 423.9 202 807
Me_Reader PHD 6.00e-12 47 215 320
Ac_Reader Tandem-PHD 3.40e-40 123.4 214 273
Organism Mus musculus
NCBI Taxa ID 10090
Functional Description
(View)
Histone acetyltransferase which may be involved in both positive and negative regulation of transcription. Required for RUNX2-dependent transcriptional activation. Component of the MOZ/MORF complex which has a histone H3 acetyltransferase activity (By similarity). Involved in cerebral cortex development.
Domain Profile
  HAT MYST

              MYST.txt  22 spfpeelkklkklyicefclkytkskes 49 
p++++ +++ + ic fcl +s+++
ENSMUSP00000066693.7 202 LPHEKDQPRADPIPICSFCLGTKESNRE 229
5778888889999*******98887654 PP
MYST.txt 4 kniekielgkyeiktwysspfpeelkklkklyicefclkytkskeslkrhlkkCklrkpPgneiyrkdklsvfevdGkkqklycqnlCl 92
++ ++ie+gkyei+twyssp+p+e+++l+kly+cefclky+ksk++l rh kkC +++pP+neiyr+++lsvfevdG+++k+ycqnlCl
ENSMUSP00000066693.7 536 RYPSVIEFGKYEIQTWYSSPYPQEYARLPKLYLCEFCLKYMKSKNILLRHSKKCGWFHPPANEIYRRKDLSVFEVDGNMSKIYCQNLCL 624
67889************************************************************************************ PP
MYST.txt 93 laklfldhktlyydvepflFYvltetdekgahlvGyFskekesaekynlaCilvlPpyqrkGyGklLiefsYelsrkegkigsPekPLs 181
laklfldhktlyydvepflFYvlt++dekg+hlvGyFskek +++kyn++Ci+++P++qr+G+G++Li+fsY+lsr+eg++gsPekPLs
ENSMUSP00000066693.7 625 LAKLFLDHKTLYYDVEPFLFYVLTKNDEKGCHLVGYFSKEKLCQQKYNVSCIMIMPQHQRQGFGRFLIDFSYLLSRREGQAGSPEKPLS 713
***************************************************************************************** PP
MYST.txt 182 dlgllsYrsyWkevllellkekeekkkitikelskatgiaveDivstleslnlikekkgqyillksekiveellklakskkkklkvdee 270
dlg+lsY++yWk+v+le+l ++++++i+ik++s+atg++++Di +tl++l++i++++g+++++++ek++ ++++ k+ ++ +++d+e
ENSMUSP00000066693.7 714 DLGRLSYLAYWKSVILEYL-YRHHERHISIKAISRATGMCPHDIATTLQHLHMIDRRDGRFVIIRREKLILGHMEKLKNCSRPNELDPE 801
*******************.99999**************************************************************** PP
MYST.txt 271 klkwkp 276
+l+w+p
ENSMUSP00000066693.7 802 SLRWTP 807
****97 PP

  Me_Reader PHD

               PHD.txt   2 tiClvC.gkddegeke....mvqCdeCddwfHlkCvklplsslpeg...kswyCpsCke 52 
+iC +C g+++ ++++ ++ C C H +C+k+ +l+++ w C +Ck+
ENSMUSP00000066693.7 215 PICSFClGTKESNREKkpeeLLSCADCGSSGHPSCLKFC-PELTANvkaLRWQCIECKT 272
69****65444443334778*****************98.34443333367******96 PP
PHD.txt 3 iClvCgkddegekemvqCdeCddwfHlkCvklplsslpegkswyCpsCke 52
+C +C+ ++++++ m+ Cd+Cd+ fH++C ++pls++p+g w+C+ C+
ENSMUSP00000066693.7 272 TCSACRVQGKNADNMLFCDSCDRGFHMECCDPPLSRMPKG-MWICQVCRP 320
7****988888888**************************.*******96 PP

  Ac_Reader Tandem-PHD

              PHD1.txt   1 inicdfclGtkesnkkkkPeelvscadcGrsGhPsclkftlelteavkalkWqciecksc 60 
i+ic+fclGtkesn++kkPeel+scadcG+sGhPsclkf++elt +vkal+Wqcieck+c
ENSMUSP00000066693.7 214 IPICSFCLGTKESNREKKPEELLSCADCGSSGHPSCLKFCPELTANVKALRWQCIECKTC 273
69********************************************************** PP
PHD1.txt 19 PeelvscadcGrsGhPscl 37
++++ c c r h c
ENSMUSP00000066693.7 283 ADNMLFCDSCDRGFHMECC 301
5778899999999999885 PP
PHD1.txt 46 avkalkWqciecks 59
+ + l W iec s
ENSMUSP00000066693.7 516 QAQELSWEKIECES 529
567799******87 PP
PHD1.txt 3 icdfclG 9
+c+fcl
ENSMUSP00000066693.7 568 LCEFCLK 574
6****95 PP

Protein Sequence
(Fasta)
MVKLANPLYT EWILEAVQKI KKQKQRPSEE RICHAVSTSH GLDKKTVSEQ LELSVQDGSV 60
LKVTNKGLAS YKDPDNPGRF SSVKPGTFPK PTKGSKGPPC NDLRNVDWNK LLKRAIEGLE 120
EPNGSSLKNI EKYLRSQSDL TGTTNHPAFQ QRLRLGAKRA VNNGRLLKEG PQYRVNSGSS 180
DGKGAPQYPS AFPSSLPPVS LLPHEKDQPR ADPIPICSFC LGTKESNREK KPEELLSCAD 240
CGSSGHPSCL KFCPELTANV KALRWQCIEC KTCSACRVQG KNADNMLFCD SCDRGFHMEC 300
CDPPLSRMPK GMWICQVCRP KKKGRKLLHE KAAQIKRRYA KPIGRPKNKL KQRLLSVTSD 360
EGSMSAFTGR GSPGRGQKTK VSTTPSSGHA ASGKHSSSRL AVTDPTRPGA TTKTTTSSTY 420
ISASTLKVNK KTKGLIDGLT KFFTPSPDGR RSRGEIIDFS KHYRPRKKVS QKQSCTSHVL 480
ATDTDIKISI KQESADVSLV GNKELVTEED LDVFKQAQEL SWEKIECESG VEDCGRYPSV 540
IEFGKYEIQT WYSSPYPQEY ARLPKLYLCE FCLKYMKSKN ILLRHSKKCG WFHPPANEIY 600
RRKDLSVFEV DGNMSKIYCQ NLCLLAKLFL DHKTLYYDVE PFLFYVLTKN DEKGCHLVGY 660
FSKEKLCQQK YNVSCIMIMP QHQRQGFGRF LIDFSYLLSR REGQAGSPEK PLSDLGRLSY 720
LAYWKSVILE YLYRHHERHI SIKAISRATG MCPHDIATTL QHLHMIDRRD GRFVIIRREK 780
LILGHMEKLK NCSRPNELDP ESLRWTPMLI SNAVVSEEER EAEKEAERLM EQASCWEKEE 840
QEILSSRVSS RQSSAKVQSK NKYLHSPERR PVAGERGQLL ELSKESSEEE EEEEEEDDEE 900
EEEEEEEESI QTSPPRLTKP QSVSIKRKRP FVVKKKRGRK RRRINSSVTT ETISETTEVL 960
NEPFDNSDEE RPMPQLEPTC EIPVEEGGRK PVLRKAFPHQ PGKKRQTEEE EGEDNHFFKT 1020
AALCRKDVDD DAEHLKEGSK DNPEPLKCRQ VWPKGAKRGL SKWKQSKERK TGFKLNLYTP 1080
PETPMEPEDQ VTIEEQKELS EDKGSPVGME REVTETVDAL LPQEGSRREE TGIPVSPHKS 1140
PGGKVDEEDL IRGEEEGEEE GEEEGEREEQ EEEEEVTTEK DLDGAKSKEN PEPEISMEKE 1200
DPVHLGDHEE DEDEEEEPSH NEDHDADDED DGHMEAANME RGDLPRETFK DALEGQEAFL 1260
DLSIQPSHSN PEVLMNCGVD LTMSCNSEPK ELAGDTGTAP ESDAEPPEEQ TQKQDQKNSD 1320
GVDAELEEGG PAAVEIDSET AQAVQSLTQE NREHDDTFPD CAETQEACRS LQNYTHTDQS 1380
PQIATTLDEC QQSDHSSPVS SVHSHPGQSV RSVNSPSVPA LENSYAQISP DQTAITVPPL 1440
QNMETSPMMD VPSVSDHSQQ VVDSGFSDLG SIESTTENYE NPSSYDSTMG GSICGNGSSQ 1500
NSCSYSSLTS SNLTQNSCAV TQQMSNISGS CSMLQQTSIS SPPTCSVKSP QGCVVERPPS 1560
SSQQLAQCSM AANFTPPMQL ADIPETSNAN IGLYERMGQS DFGAGHYPQP SATFSLAKLQ 1620
QLTNTLIDHS LPYSHSAAVT SYANSASLST PLSNTGLVQL SQSPHSVPGG PQAQATMTPP 1680
PNLTPPPMNL PPPLLQRNMA ASNIGISHSQ RLQTQIASKG HVSMRTKAAS LSPAAATHQS 1740
QIYGRSQTVA MQGPARTLTM QRGMNMSVNL MPAPAYNVNS VNMNMNTLNA MNGYSMSQPM 1800
MNSGYHSNHG YMNQTPQYPM QMQMGMMGSQ PYAQQPMQTP PHANMMYTAP GHHGYMNTGM 1860
SKQSLNGSYM RR 1872
Nucleotide Sequence
(Fasta)
GGAGGAGGAG GCGGAGGAGG AGAAGGAGGC GGCGGCGGTG GGTCCCGGGC GGGGGGAGCG 60
CGGCGCTGCG GACCCGGGCG GCTGGCAAAG GACGAGGCGG AGGCTGAGGA AGGCAGCGGG 120
GAGACCCGGT CTGCAGCAAC AAAGGGCAGC AAGCGATTGG CCGGGCTGGA GGCGAGGTCT 180
TGGTTTCCTA AAGATGTCTT TCACTTGAAG AGTGCAGTCC TTCCCATTGG TGAACTAAGA 240
CAACTCTCCA CGTTGCCTGG CAGTCAGTCC TCTCTTTAAG GATGGTTGTC CCTATGCTGT 300
TGCTTCACAT GGGCTGGGAT CCTCTGCCCT TGTGTTGAAT TGTGACTTTG GAATGTGCAG 360
GTTGTGTTAA GTACAAGGCG AATCTCTATG GGTAACGTCT GTGTTGGAGA AGCCATTTGT 420
CAACCATGGT AAAACTTGCA AACCCACTTT ACACAGAGTG GATTCTTGAA GCAGTGCAGA 480
AAATCAAGAA GCAGAAGCAG CGGCCCTCAG AAGAGAGGAT CTGCCATGCG GTCAGCACGT 540
CCCATGGGTT GGACAAGAAA ACAGTCTCGG AACAGCTGGA ACTTAGTGTT CAGGATGGCT 600
CCGTTCTCAA AGTCACCAAC AAAGGCCTTG CTTCATATAA GGACCCAGAC AATCCTGGGC 660
GTTTTTCATC GGTTAAACCG GGCACTTTCC CCAAGCCAAC CAAGGGGTCC AAAGGACCGC 720
CGTGTAATGA TCTACGCAAT GTGGATTGGA ATAAACTTTT AAAGAGAGCA ATCGAAGGCC 780
TTGAGGAGCC AAACGGCTCC TCCTTGAAGA ACATTGAGAA GTATCTGAGA AGCCAGAGTG 840
ATCTTACAGG CACCACCAAC CATCCAGCCT TTCAGCAGAG GTTGCGGCTA GGGGCCAAGC 900
GTGCTGTGAA CAATGGGAGG TTACTGAAGG AAGGACCACA GTACAGGGTC AATAGTGGGA 960
GCTCAGATGG CAAAGGGGCG CCCCAGTACC CCAGTGCTTT TCCGTCCTCA CTCCCGCCCG 1020
TCAGCCTTCT ACCCCATGAG AAAGACCAGC CCCGTGCCGA TCCCATTCCA ATATGTAGCT 1080
TCTGTTTGGG GACTAAAGAG TCAAATCGTG AAAAGAAACC AGAAGAACTC CTGTCTTGTG 1140
CAGATTGTGG CAGTAGTGGA CACCCATCCT GTCTGAAGTT TTGTCCTGAG TTAACCGCAA 1200
ATGTGAAGGC CTTGAGGTGG CAGTGCATCG AGTGCAAGAC GTGCAGCGCA TGTCGAGTCC 1260
AGGGCAAAAA TGCAGATAAC ATGCTTTTTT GTGATTCCTG TGATAGAGGA TTCCATATGG 1320
AGTGCTGTGA CCCACCACTT TCCAGAATGC CAAAAGGGAT GTGGATTTGC CAAGTCTGCA 1380
GACCAAAGAA AAAGGGAAGA AAACTACTTC ATGAGAAAGC TGCACAAATA AAACGGCGAT 1440
ATGCAAAACC CATTGGACGA CCGAAAAATA AATTAAAGCA ACGATTGTTG TCTGTAACCA 1500
GTGATGAAGG ATCCATGAGT GCATTCACAG GAAGGGGGTC ACCTGGTAGG GGTCAAAAGA 1560
CTAAAGTCAG TACCACACCT TCATCTGGTC ATGCTGCGTC TGGGAAGCAC TCAAGCAGCA 1620
GATTGGCTGT TACAGACCCC ACCCGGCCTG GTGCCACCAC CAAAACCACC ACCTCCTCCA 1680
CCTACATTTC TGCCTCTACA CTTAAAGTTA ACAAGAAAAC CAAAGGGCTC ATTGATGGCC 1740
TTACTAAGTT TTTTACACCA TCACCTGATG GTCGCAGATC CCGAGGTGAA ATAATAGACT 1800
TTTCAAAGCA CTATCGTCCA AGGAAAAAGG TCTCTCAGAA ACAGTCATGC ACTTCTCATG 1860
TGTTGGCTAC AGATACTGAT ATTAAAATAA GCATCAAACA AGAAAGTGCA GATGTGAGTC 1920
TGGTGGGAAA CAAGGAGCTC GTGACTGAAG AGGATCTGGA CGTTTTTAAG CAGGCCCAGG 1980
AACTGTCTTG GGAGAAAATA GAGTGTGAAA GTGGAGTGGA AGACTGTGGT CGGTACCCCT 2040
CAGTAATAGA GTTCGGGAAA TACGAGATCC AAACCTGGTA CTCCTCGCCT TACCCACAGG 2100
AATATGCAAG ATTACCAAAG CTTTACCTGT GTGAATTCTG TCTTAAATAT ATGAAGAGTA 2160
AAAATATTTT GCTAAGACAC TCAAAGAAGT GTGGATGGTT TCATCCTCCG GCCAATGAGA 2220
TTTACCGAAG GAAAGACCTT TCAGTATTCG AGGTTGATGG GAATATGAGT AAAATTTATT 2280
GCCAAAACCT TTGCTTGTTA GCCAAGCTCT TCCTGGACCA CAAAACATTG TATTATGATG 2340
TTGAGCCATT CCTTTTTTAT GTCCTTACAA AAAATGATGA AAAAGGCTGT CATCTGGTTG 2400
GATACTTCTC CAAGGAAAAG CTCTGCCAGC AGAAGTATAA TGTGTCCTGC ATAATGATCA 2460
TGCCCCAGCA CCAAAGGCAA GGATTTGGAC GCTTTCTCAT TGATTTCAGC TATTTGCTTT 2520
CTCGAAGAGA AGGCCAAGCA GGGTCTCCCG AAAAGCCGCT CTCTGACCTG GGCCGGCTCT 2580
CCTACCTGGC CTACTGGAAA AGTGTCATCT TGGAATACCT CTACCGCCAC CACGAGAGGC 2640
ACATCAGCAT CAAGGCCATT AGCAGAGCCA CAGGCATGTG CCCACATGAC ATCGCCACCA 2700
CTCTGCAGCA CCTCCACATG ATTGACAGGA GGGATGGCAG GTTTGTCATC ATTAGAAGGG 2760
AAAAGTTGAT ATTGGGCCAC ATGGAAAAGC TGAAGAACTG TTCCCGACCC AATGAACTTG 2820
ATCCGGAGAG TCTAAGATGG ACCCCAATGT TAATTTCTAA TGCTGTGGTT TCTGAGGAAG 2880
AGCGAGAAGC TGAGAAGGAG GCTGAACGAC TAATGGAACA AGCCAGCTGC TGGGAGAAGG 2940
AGGAGCAAGA GATCCTGTCG TCCAGAGTTA GCAGTAGGCA ATCGTCTGCA AAAGTACAAT 3000
CAAAGAATAA GTACCTGCAC TCCCCAGAGA GGCGGCCAGT GGCCGGGGAG CGAGGACAGT 3060
TGTTAGAGCT GTCCAAAGAG AGCAGTGAGG AAGAGGAGGA GGAGGAGGAG GAAGATGATG 3120
AGGAAGAGGA GGAGGAGGAA GAGGAGGAGA GCATTCAGAC ATCTCCCCCT CGGTTGACTA 3180
AGCCACAGTC AGTTTCCATT AAAAGAAAGA GGCCTTTTGT AGTAAAGAAG AAAAGGGGTC 3240
GTAAACGCAG GAGGATCAAC AGCAGTGTCA CCACCGAGAC CATTTCCGAG ACGACAGAAG 3300
TGCTCAATGA GCCCTTCGAC AACTCGGATG AGGAGAGGCC AATGCCGCAG CTGGAGCCTA 3360
CCTGTGAGAT CCCAGTGGAG GAGGGCGGCA GGAAGCCAGT TCTGAGGAAA GCATTCCCAC 3420
ATCAGCCAGG GAAGAAAAGG CAGACAGAGG AAGAGGAAGG GGAAGACAAT CATTTCTTCA 3480
AGACCGCTGC CCTTTGTAGA AAAGATGTAG ATGATGATGC AGAACACTTG AAAGAAGGCA 3540
GCAAAGACAA TCCTGAGCCT CTAAAGTGCA GACAAGTGTG GCCAAAAGGA GCGAAGCGAG 3600
GGCTCTCCAA GTGGAAGCAA AGCAAGGAGA GGAAGACGGG CTTCAAGCTG AACCTGTACA 3660
CCCCACCAGA GACACCCATG GAGCCAGAGG ACCAGGTGAC GATCGAAGAG CAGAAGGAGC 3720
TTTCAGAGGA CAAGGGCAGC CCCGTGGGGA TGGAACGGGA GGTGACAGAG ACCGTGGATG 3780
CCTTGCTGCC TCAGGAGGGG AGCAGAAGGG AAGAGACAGG CATACCCGTG AGTCCACATA 3840
AATCACCAGG TGGAAAGGTA GATGAGGAGG ACCTCATCAG AGGTGAGGAG GAGGGAGAGG 3900
AAGAGGGAGA GGAGGAGGGA GAACGAGAAG AACAGGAAGA GGAAGAAGAA GTAACTACAG 3960
AAAAAGACCT AGATGGTGCT AAAAGTAAAG AGAACCCGGA GCCTGAGATC TCCATGGAAA 4020
AGGAAGACCC TGTGCATCTG GGTGACCATG AAGAGGACGA GGATGAGGAG GAAGAGCCAT 4080
CTCACAATGA GGACCATGAT GCAGATGATG AAGATGATGG CCACATGGAG GCTGCCAACA 4140
TGGAGAGGGG AGACCTCCCA AGAGAAACCT TCAAAGACGC ACTAGAGGGC CAGGAGGCTT 4200
TTTTAGACCT GAGCATTCAG CCGAGTCACT CGAACCCTGA AGTCTTGATG AACTGCGGTG 4260
TTGATCTCAC AATGTCCTGT AACAGTGAGC CAAAGGAGCT TGCTGGGGAC ACTGGAACTG 4320
CACCTGAGTC TGACGCGGAG CCCCCGGAAG AACAGACACA GAAGCAGGAC CAAAAGAACA 4380
GCGATGGTGT GGATGCTGAG CTCGAAGAGG GAGGCCCAGC CGCTGTGGAA ATTGACTCCG 4440
AGACCGCCCA GGCTGTTCAG TCTTTGACCC AAGAAAACAG GGAGCACGAT GACACCTTTC 4500
CAGATTGTGC TGAGACTCAA GAGGCCTGTA GAAGCCTGCA GAACTATACA CACACAGACC 4560
AAAGTCCTCA AATTGCCACC ACGCTGGACG AGTGCCAACA GTCAGACCAC AGTAGCCCAG 4620
TTTCATCTGT CCATTCCCAT CCTGGCCAGT CAGTTCGTTC TGTCAATAGC CCCAGTGTCC 4680
CTGCCCTAGA GAATAGCTAT GCCCAAATCA GCCCCGATCA GACTGCCATC ACAGTGCCAC 4740
CTCTGCAGAA CATGGAGACC AGTCCAATGA TGGACGTCCC GTCAGTGTCA GATCACTCAC 4800
AGCAGGTCGT TGACAGCGGA TTCAGTGACC TGGGCAGTAT TGAGAGCACA ACAGAGAACT 4860
ATGAGAACCC AAGCAGCTAT GACTCAACCA TGGGAGGCAG TATCTGTGGA AACGGCTCTT 4920
CCCAGAACAG CTGCTCCTAC AGCAGTCTCA CCTCTAGCAA TCTGACACAG AACAGCTGTG 4980
CTGTCACCCA GCAGATGTCC AACATCAGTG GGAGCTGCAG CATGCTGCAG CAGACCAGCA 5040
TCAGCTCCCC TCCAACCTGC AGCGTCAAGT CTCCCCAAGG CTGTGTGGTG GAGAGGCCTC 5100
CCAGTAGCAG CCAGCAGCTG GCTCAGTGCA GCATGGCCGC CAATTTCACC CCACCCATGC 5160
AGCTGGCTGA CATCCCCGAG ACCAGCAATG CCAACATTGG CTTATATGAG CGAATGGGTC 5220
AAAGTGATTT TGGGGCTGGG CACTACCCAC AGCCATCTGC CACCTTCAGC CTTGCCAAAC 5280
TGCAGCAGTT AACTAATACA CTTATTGATC ATTCATTGCC TTACAGCCAT TCCGCTGCTG 5340
TGACCTCCTA TGCAAACAGT GCCTCTTTGT CCACACCATT AAGTAACACA GGGCTTGTTC 5400
AGCTTTCGCA GTCTCCACAC TCTGTCCCTG GAGGGCCCCA AGCACAAGCT ACCATGACCC 5460
CACCCCCTAA CCTGACTCCT CCTCCCATGA ATCTGCCACC ACCTCTCCTG CAGCGGAACA 5520
TGGCTGCATC AAATATTGGC ATCTCCCACA GCCAAAGACT GCAAACTCAG ATTGCCAGCA 5580
AGGGCCACGT CTCCATGAGA ACCAAGGCGG CATCTCTGTC ACCAGCTGCC GCCACCCATC 5640
AGTCACAAAT CTATGGGCGT TCCCAGACTG TAGCCATGCA GGGTCCTGCA CGGACTTTAA 5700
CGATGCAAAG AGGCATGAAC ATGAGTGTGA ACTTGATGCC AGCGCCAGCC TACAATGTCA 5760
ACTCGGTGAA CATGAACATG AACACTCTGA ATGCCATGAA TGGGTATAGC ATGTCCCAGC 5820
CGATGATGAA CAGTGGTTAC CACAGCAACC ACGGCTATAT GAATCAAACC CCCCAGTACC 5880
CTATGCAGAT GCAGATGGGC ATGATGGGAA GCCAGCCATA CGCCCAGCAG CCAATGCAGA 5940
CCCCACCCCA CGCTAACATG ATGTACACGG CCCCCGGACA CCACGGCTAC ATGAACACAG 6000
GCATGTCCAA ACAGTCTCTC AATGGGTCCT ACATGAGAAG GTAGACAGCC TGGCAGCCCA 6060
CCCAGCCCAC TGGGCCCCAC TATTGGATTG ATCTGCACAA ATACCTTTGA AGAGTACGAT 6120
TTCAAAACCA GCATTGGTGT GAATGCAAAA ACATTTGTTG GCACCATTTA TTTAAAAAAA 6180
AAAAAGCTGT ATGCAGCAGA AAGAAAGCCT TATACAAGTT GTTTTTCTTT TTTCCTTTTT 6240
TTCTTTTTTG GTACCTTTAT TTCTGTTACT TTTATATAAA ATTCTCTGCA AAGGAAGGCC 6300
TCTCTTAGGA CTCTAGTTGG CAGCGGCCAC ACGTCGTGCC TGCTTCCATT AAACAGTGTG 6360
GATACAAGCC CCTCCCCAAA TCACCTGTTT TAATACTGAA CCTCCAGCTT TTCTCCTTCC 6420
TGTCTACTCC ATGGAAATGC CTTTAGCATT TCAATTACTG TATATTTTGT TTAAGGTGAC 6480
CCTTCAGCAT GCCGCTAATG TCTTTGTTAG TGACAGTGCA TTTTGTAGTA CTGTACAAGT 6540
GTTGTGCTAA CGGTAAGCCA TTTCTTAAGT TTTTTGCCTT GATTAGGGTA CCCTAATTTG 6600
AGGGTTAAAA AAAACAAAAC AAAACAAAGC TCTATTTTTG TTAATTATAA AACTGTAAAG 6660
AGCTACAGAG CTATCCCCGT CTGGTTAGTG AAGGGGGTTT ATCGCTAAAT GTTTGGTGTA 6720
AAGTTGAGAA GACCTTTTTC CATTTTGGTG GCAGGCTCCT TTGGGGGGAG GCAGCTTTCT 6780
GTTTTATAAA TGCACACTTC TGTTTATTGA ATGAAGCATA TCTCAGTGTT TATCTGTCAG 6840
GTTTTGAAGC ATTTCATATA TGTCCAAATA CTTGGCAGGA TTTAAAAAAA AATAGTGAAT 6900
TTGGTGTAAA GTTGCTATTT TATGGAAATG CCTCTAACTT TACATTTTCA TTCCATCTGT 6960
AGATTTTTCT ATCTTTATAA AATATTGGAG TTATTTTTTA AGGAAAAATA GAAAAGTAGC 7020
TTGTGAATAG CTCAAACTAA GCTTACAAAT CGCATGTAAA AAAGCAGAAA AGTTATTTGT 7080
GTCTGTTTCT ATTGCGTCCT TTTTTAGCCT TTGTACCTGG ACAGGTGACA GTAAGGGCCA 7140
AGCAGGAGAG GCGGGCGCGG CCTTGTATAA AATAGGAGCC AGCGGGACTC TTGTATCTAC 7200
CTGTTCTCTT TTTAGTCAGT TACTTCAAAA AAAAGAAAAA GCAAAAACAA AAAAACAAAA 7260
GCTGTACATT TTAACATAAA ATAAATTATG ATGAGCCATT TCTAGCCTCT CGTGTCCTGT 7320
CATGTTATGA TTGATGGAGA ATGACCAGCT GAGCTGTGTC ATGTGTCACA TTTCAGAACA 7380
CATACACGAT GGGGGAAATA AATTATTTAG TGTAAATTGA AGTTATGAGA TTTTTTTTTT 7440
CTGATTTGTT TTGACTTTGG GGGAGGGGTT GGCAATAAGT ATGAATGAGT ACTATCTAAT 7500
AAAACCATCA CCTATACCAA ATACCTATTT AATAAATTAA TTTATAATGG ATTTTAATGC 7560
TTTTCCATGA AAGTTGACTT TATGCTGGTG CATACCTTCT GTATGCCAAT CATTGTCTTT 7620
AAATAAAGTG AGTTTGGTTT TTTCTTTTT
Sequence Source Ensembl
Keyword

KW-0007--Acetylation
KW-0010--Activator
KW-0012--Acyltransferase
KW-0025--Alternative splicing
KW-0156--Chromatin regulator
KW-0181--Complete proteome
KW-1017--Isopeptide bond
KW-0479--Metal-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0677--Repeat
KW-0678--Repressor
KW-0804--Transcription
KW-0805--Transcription regulation
KW-0808--Transferase
KW-0832--Ubl conjugation
KW-0862--Zinc
KW-0863--Zinc-finger
--

Interpro

IPR016181--Acyl_CoA_acyltransferase
IPR002717--HAT_MYST-type
IPR005818--Histone_H1/H5_H15
IPR011991--WHTH_DNA-bd_dom
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS51504--H15
PS51726--MYST_HAT
PS01359--ZF_PHD_1
PS50016--ZF_PHD_2

Pfam

PF00538--Linker_histone
PF01853--MOZ_SAS
PF00628--PHD

Gene Ontology

GO:0070776--C:MOZ/MORF histone acetyltransferase complex
GO:0000786--C:nucleosome
GO:0016407--F:acetyltransferase activity
GO:0003677--F:DNA binding
GO:0004402--F:histone acetyltransferase activity
GO:0008134--F:transcription factor binding
GO:0008270--F:zinc ion binding
GO:0016573--P:histone acetylation
GO:0043966--P:histone H3 acetylation
GO:0045892--P:negative regulation of transcription, DNA-templated
GO:0006334--P:nucleosome assembly
GO:0045944--P:positive regulation of transcription from RNA polymerase II promoter
GO:0045893--P:positive regulation of transcription, DNA-templated
GO:0006351--P:transcription, DNA-templated

Orthology
WERAM ID Ensembl Protein ID Species Identity E-value Score
WERAM-Ict-0096 ENSSTOP00000010025.2 Ictidomys tridecemlineatus 91 0.0 2893
WERAM-Mam-0215 ENSMMUP00000030925.2 Macaca mulatta 90 0.0 2864
WERAM-Orc-0167 ENSOCUP00000014911.3 Oryctolagus cuniculus 90 0.0 2839
WERAM-Nol-0185 ENSNLEP00000020448.2 Nomascus leucogenys 89 0.0 2524
WERAM-Chs-0110 ENSCSAP00000005308.1 Chlorocebus sabaeus 88 0.0 2006
WERAM-Hos-0272 ENSP00000486595.1 Homo sapiens 88 0.0 2004
WERAM-Gog-0099 ENSGGOP00000008565.2 Gorilla gorilla 88 0.0 2003
WERAM-Pat-0021 ENSPTRP00000004608.5 Pan troglodytes 89 0.0 2002
WERAM-Poa-0023 ENSPPYP00000002692.2 Pongo abelii 88 0.0 2001
WERAM-Paa-0171 ENSPANP00000020274.1 Papio anubis 87 0.0 1999
WERAM-Dan-0056 ENSDNOP00000017553.2 Dasypus novemcinctus 88 0.0 1990
WERAM-Cap-0082 ENSCPOP00000005892.2 Cavia porcellus 85 0.0 1987
WERAM-Ova-0090 ENSOARP00000009313.1 Ovis aries 88 0.0 1967
WERAM-Bot-0036 ENSBTAP00000003798.4 Bos taurus 88 0.0 1967
WERAM-Eqc-0081 ENSECAP00000010370.1 Equus caballus 89 0.0 1967
WERAM-Otg-0164 ENSOGAP00000013816.2 Otolemur garnettii 88 0.0 1966
WERAM-Aim-0026 ENSAMEP00000001875.1 Ailuropoda melanoleuca 88 0.0 1961
WERAM-Sus-0074 ENSSSCP00000011001.2 Sus scrofa 88 0.0 1956
WERAM-Caj-0010 ENSCJAP00000002250.2 Callithrix jacchus 86 0.0 1940
WERAM-Mup-0033 ENSMPUP00000003295.1 Mustela putorius furo 87 0.0 1939
WERAM-Caf-0158 ENSCAFP00000022633.4 Canis familiaris 87 0.0 1936
WERAM-Fec-0057 ENSFCAP00000005151.3 Felis catus 87 0.0 1927
WERAM-Myl-0085 ENSMLUP00000006798.2 Myotis lucifugus 86 0.0 1895
WERAM-Ptv-0099 ENSPVAP00000009046.1 Pteropus vampyrus 85 0.0 1846
WERAM-Mim-0001 ENSMICP00000000022.1 Microcebus murinus 86 0.0 1810
WERAM-Ran-0083 ENSRNOP00000064386.2 Rattus norvegicus 91 0.0 1785
WERAM-Sah-0096 ENSSHAP00000011021.1 Sarcophilus harrisii 85 0.0 1760
WERAM-Ect-0112 ENSETEP00000012551.1 Echinops telfairi 81 0.0 1704
WERAM-Mod-0005 ENSMODP00000000887.5 Monodelphis domestica 78 0.0 1679
WERAM-Anp-0093 ENSAPLP00000010721.1 Anas platyrhynchos 76 0.0 1635
WERAM-Tag-0100 ENSTGUP00000006836.1 Taeniopygia guttata 74 0.0 1625
WERAM-Gaga-0054 ENSGALP00000008060.4 Gallus gallus 76 0.0 1625
WERAM-Fia-0090 ENSFALP00000007269.1 Ficedula albicollis 75 0.0 1624
WERAM-Ora-0060 ENSOANP00000009404.2 Ornithorhynchus anatinus 90 0.0 1519
WERAM-Ten-0162 ENSTNIP00000006152.1 Tetraodon nigroviridis 70 0.0 1159
WERAM-Tut-0005 ENSTTRP00000000341.1 Tursiops truncatus 79 0.0 1155
WERAM-Orla-0087 ENSORLP00000010755.1 Oryzias latipes 69 0.0 1123
WERAM-Meg-0033 ENSMGAP00000002954.2 Meleagris gallopavo 64 0.0 1105
WERAM-Tub-0015 ENSTBEP00000001544.1 Tupaia belangeri 67 0.0 1095
WERAM-Loa-0054 ENSLAFP00000004071.3 Loxodonta africana 66 0.0 1091
WERAM-Pes-0065 ENSPSIP00000008405.1 Pelodiscus sinensis 65 0.0 1069
WERAM-Anc-0133 ENSACAP00000012299.3 Anolis carolinensis 65 0.0 1061
WERAM-Dio-0138 ENSDORP00000012841.1 Dipodomys ordii 64 0.0 1045
WERAM-Mae-0035 ENSMEUP00000002978.1 Macropus eugenii 62 0.0 998
WERAM-Xim-0123 ENSXMAP00000010545.1 Xiphophorus maculatus 60 0.0 990
WERAM-Pof-0025 ENSPFOP00000001872.2 Poecilia formosa 59 0.0 988
WERAM-Prc-0040 ENSPCAP00000003620.1 Procavia capensis 89 0.0 984
WERAM-Vip-0046 ENSVPAP00000004212.1 Vicugna pacos 62 0.0 960
WERAM-Tas-0050 ENSTSYP00000004605.1 Tarsius syrichta 60 0.0 901
WERAM-Ocp-0127 ENSOPRP00000013509.1 Ochotona princeps 57 0.0 888
WERAM-Ere-0048 ENSEEUP00000004233.1 Erinaceus europaeus 79 0.0 860
WERAM-Soa-0082 ENSSARP00000007754.1 Sorex araneus 93 0.0 853
WERAM-Lac-0049 ENSLACP00000007072.1 Latimeria chalumnae 70 0.0 759
WERAM-Chh-0001 ENSCHOP00000000101.1 Choloepus hoffmanni 81 0.0 725
WERAM-Leo-0031 ENSLOCP00000005426.1 Lepisosteus oculatus 65 0.0 693
WERAM-Orn-0196 ENSONIP00000020390.1 Oreochromis niloticus 59 0.0 638
WERAM-Tar-0157 ENSTRUP00000034035.1 Takifugu rubripes 58 0.0 634
WERAM-Gaa-0019 ENSGACP00000002833.1 Gasterosteus aculeatus 70 8e-177 619
WERAM-Asm-0039 ENSAMXP00000004916.1 Astyanax mexicanus 65 1e-172 605
WERAM-Dar-0112 ENSDARP00000072241.3 Danio rerio 65 1e-166 585
WERAM-Gam-0083 ENSGMOP00000008636.1 Gadus morhua 65 9e-151 533
WERAM-Drm-0054 FBpp0072159 Drosophila melanogaster 64 2e-109 395
WERAM-Xet-0138 ENSXETP00000047416.3 Xenopus tropicalis 56 3e-101 368
WERAM-Pem-0064 ENSPMAP00000007030.1 Petromyzon marinus 56 3e-100 365
WERAM-Cii-0017 ENSCINP00000006517.3 Ciona intestinalis 54 3e-97 355
WERAM-Cis-0023 ENSCSAVP00000005035.1 Ciona savignyi 54 6e-97 354
WERAM-Asc-0022 CADACLAP00004828 Aspergillus clavatus 49 2e-83 309
WERAM-Ast-0034 CADATEAP00009194 Aspergillus terreus 48 4e-83 308
WERAM-Zem-0080 GRMZM2G140288_P01 Zea mays 56 4e-83 308
WERAM-Orl-0045 KN538920.1_FGP012 Oryza longistaminata 56 4e-83 308
WERAM-Art-0119 AT5G09740.1 Arabidopsis thaliana 55 8e-83 307
WERAM-Orbr-0089 OB07G28490.1 Oryza brachyantha 56 1e-82 306
WERAM-Asfu-0035 CADAFUAP00007935 Aspergillus fumigatus 48 2e-82 306
WERAM-Orp-0078 OPUNC07G21500.1 Oryza punctata 56 2e-82 305
WERAM-Ors-0074 OS07T0626600-01 Oryza sativa 56 3e-82 305
WERAM-Orr-0084 ORUFI07G24020.1 Oryza rufipogon 56 3e-82 305
WERAM-Orni-0080 ONIVA07G22490.1 Oryza nivara 56 3e-82 305
WERAM-Orm-0076 OMERI07G19290.1 Oryza meridionalis 56 3e-82 305
WERAM-Glm-0035 GLYMA04G16180.1 Glycine max 55 3e-82 305
WERAM-Ori-0077 BGIOSGA023877-PA Oryza indica 56 3e-82 305
WERAM-Thc-0095 EOY16150 Theobroma cacao 55 3e-82 305
WERAM-Pot-0027 POPTR_0002s09010.1 Populus trichocarpa 55 3e-82 305
WERAM-Asn-0016 CADANIAP00003430 Aspergillus nidulans 52 3e-82 305
WERAM-Orgl-0078 OGLUM07G22920.1 Oryza glumaepatula 56 4e-82 305
WERAM-Mua-0086 GSMUA_Achr6P10570_001 Musa acuminata 56 5e-82 304
WERAM-Met-0059 AES68391 Medicago truncatula 55 6e-82 304
WERAM-Lep-0080 LPERR07G19900.1 Leersia perrieri 56 7e-82 304
WERAM-Asni-0011 CADANGAP00004195 Aspergillus niger 52 7e-82 304
WERAM-Orb-0081 OBART07G22890.1 Oryza barthii 56 7e-82 304
WERAM-Viv-0113 VIT_18s0001g04100.t01 Vitis vinifera 55 8e-82 303
WERAM-Org-0080 ORGLA07G0178500.1 Oryza glaberrima 56 9e-82 303
WERAM-Arl-0101 fgenesh2_kg.6__ 927__ AT5G09740.1 Arabidopsis lyrata 54 1e-81 303
WERAM-Sol-0133 Solyc11g013520.1.1 Solanum lycopersicum 54 1e-81 303
WERAM-Sob-0038 Sb02g039960.1 Sorghum bicolor 56 1e-81 303
WERAM-Asf-0007 CADAFLAP00002066 Aspergillus flavus 48 1e-81 303
WERAM-Bro-0183 Bo9g173870.1 Brassica oleracea 54 1e-81 303
WERAM-Aso-0012 CADAORAP00001649 Aspergillus oryzae 48 1e-81 303
WERAM-Nec-0023 EFNCRP00000004537 Neurospora crassa 51 2e-81 303
WERAM-Brr-0045 Bra009399.1-P Brassica rapa 54 2e-81 303
WERAM-Amt-0019 ERM94321 Amborella trichopoda 54 2e-81 302
WERAM-Php-0014 PP1S13_111V6.1 Physcomitrella patens 54 2e-81 302
WERAM-Prp-0062 EMJ23350 Prunus persica 54 2e-81 302
WERAM-Brd-0008 BRADI1G20770.1 Brachypodium distachyon 55 3e-81 302
WERAM-Gag-0004 GGTG_01203T0 Gaeumannomyces graminis 52 4e-81 301
WERAM-Sei-0114 Si029855m Setaria italica 55 5e-81 301
WERAM-Mao-0013 MGG_04615T0 Magnaporthe oryzae 53 7e-81 300
Created Date 25-Jun-2016