WERAM Information

Tag Content
WERAM ID WERAM-Mum-0150
Ensembl Protein ID ENSMUSP00000133700.1
Uniprot Accession Q69ZK6; JHD2C_MOUSE; E9QMM8; Q6NV48; Q8BUF5; Q8C4I5; Q8C5Q9
Genbank Protein ID NP_001229325.1; XP_006513104.1; XP_006513105.1
Protein Name Probable JmjC domain-containing histone demethylation protein 2C
Genbank Nucleotide ID NM_001242396.1; XM_006513041.1; XM_006513042.2
Gene Name JMJD1C;JHDM2C
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSMUSG00000037876.16 ENSMUST00000173689.7 ENSMUSP00000133700.1
ENSMUSG00000037876.16 ENSMUST00000051446.15 ENSMUSP00000056227.9
ENSMUSG00000037876.16 ENSMUST00000174408.7 ENSMUSP00000134551.1
ENSMUSG00000037876.16 ENSMUST00000173762.1 ENSMUSP00000134678.1
Details
Type Family Domain Substrates AA References (PMIDs)
HDM JHDM2 Jmjc H3K9me2 K 26494788
Status Reviewed
Classification
Type Family E-value Score Start End
HDM JHDM2 3.70e-95 319 2099 2308
Organism Mus musculus
NCBI Taxa ID 10090
Functional Description
(View)		 Probable histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a central role in histone code. Demethylation of Lys residue generates formaldehyde and succinate. May be involved in hormone-dependent transcriptional activation, by participating in recruitment to androgen-receptor target genes (By similarity).
Domain Profile
  HDM JHDM2
             JHDM2.txt    1 eYckrdgklNLasklpknfvrpdlgPklynAyGlateedrklgttnlhldvsdavnilvyvgilkkkwaeedlkellksieeeelde 87  
                            eYc+ +gk+NLas+lp +fvrpdlgP+l++AyG+a+++d+++gttnlh++ sd+vn+lvyvgi+k++   ++ + +lk++eeeeld+
  ENSMUSP00000133700.1 2099 EYCNPEGKFNLASHLPGFFVRPDLGPRLCSAYGVAAAKDHDIGTTNLHIEASDVVNVLVYVGIAKGNGVLSK-AGILKKFEEEELDD 2184
                            8**********************************************************************9.************** PP
             JHDM2.txt   88 vtrkrvqdpkekpgalWhifaakdaekirellekvskeqgaevppdhdpihdqswyldrklrkrLfeeyGvegwtlvQklgdavlip 174 
                            v rkr++d++e pgalWhi+a kd++kire+l+k+skeqg ev+p+hdpi+dqswy++rklr+rL eeyGv+++tl+Q+lgda+++p
  ENSMUSP00000133700.1 2185 VLRKRLKDSSEIPGALWHIYAGKDVDKIREFLQKISKEQGLEVLPEHDPIRDQSWYVNRKLRQRLLEEYGVRACTLIQFLGDAIVLP 2271
                            *************************************************************************************** PP
             JHDM2.txt  175 agapHqvqnlkscvkvaedFvsPEnvkecfrltkeyr 211 
                            ag++Hqvqn++scv+v+edFvsPE+++++f+lt+e+r
  ENSMUSP00000133700.1 2272 AGTLHQVQNFHSCVQVTEDFVSPEHLVQSFHLTQELR 2308
                            **********************************987 PP
Protein Sequence
(Fasta)		MQGPYSLNGY RVRVYRQDSA TQWFTGIITH HDLFTRTMIV MNDQVLEPQN VDPSMVQMTF 60
LDDVVHSLLK GENIGITSRR RSRASQNIST VHGHYTRAQA NSPRPAMNSQ AAVPKQNTHQ 120
QQQQRSIRPN KRKGSDSSIP DEEKMKEDKY DCVSRGENPK GKNKHVVTKR RKPEEAEKRL 180
SMKRLRTDNA SDASESSDAE SSSKRVTETS SSEPMPEYEP KNKVTSKVNG EEGQSQAAEE 240
AGEETLIDTR PPWDQMQEDK NHNEGEKPKS TDSHLQDKMT LRSSEQATVA DHNSNDSVLQ 300
ECNVENQRTV ELLPKDRLVS RTPTPKCVTD IKNDTHSERA AQENLNTFGL QTPENMDPNV 360
SDSKHSNAKY LETAKQDCDQ SWVSDVVKVD LTQSSVTNAP SGSDKRDTEK ERNHYVSYMS 420
SLSAVSVTED QLHKRSPPPE TIKAKLTTSV DTQKAKSSSS PEVVKPKITH SPDSVKSKAA 480
YGNSQAVGER RLANKIEHEL SRGSFHPVPT RGSALETTKS PLIIDKNEHF TVYRDPALIG 540
SETGANHISP FLSQHPFSLH SSSHRTCLNP GTHHPALTPG PHLLAGSTSQ TPLPTINTHP 600
LTSGPHHPVH HPHLLPTVLP GVPTASLLGG HPRLESAHAS SLSHLALAHQ QQQQLLQHQS 660
PHLLGQAHPS ASYNQLGLYP IIWQYPNGTH AYSGLGLPSS KWVHPENAVN AEASLRRNSP 720
SPWLHQPTPV TSADGIGLLS HIPVRPSSAE PHRPHKITVH SSPPLTKTLA DHHKEELERK 780
AFMEPLRSNA STSVKGDLDL NRSQAGKDCH LHRHFVGPRP PQETGERLNK YKEEHRRILQ 840
ESIDVAPFTT KIKGHEVERE NYSRVVPSSS SPKSHAIKQD KDVDRSVSEI YKMKHSVPQS 900
LPQSNYFTTL SNSVVNEPPR SYPSKEVSNI YTEKQNNNLS ATANPQTHSF ISSLSKPPPL 960
IKHQPESESL VGKIPDHLPH QSASHSVTTF RSDCRSPTHL TVSSTNALRS MPALHRAPVF 1020
HPPIHHSLER KESSYSSLSP PTLTPVMPVN AGGKVQESQK PPTLIPEPKD SQSNFKNSSD 1080
QSLTEMWRSN NNLNREKAEW PVEKSSGKSQ AAVASVIVRP PSSTKVDSVP SVPLASKDRV 1140
CERSSSGANK TDYLKPEAGE TGRIILPNVN LESAHVKSEK NFEAVSQGNV PVSVMSAVNV 1200
VSTTKADVFT SAATTTSVSS LSSAETSYSL SNTISASTPF ECTSSKSVVS QAVAQAKDCT 1260
VSTAVPGTLA CSKTGSAVQP GSGFSGTTDF IHLKKHKAAL AAAQFKNSSV SEAELNTVRN 1320
QTVAASLPLD STMTCTASNK AISVGNGPAA QSSQPNYHTK LKKAWLTRHS EEDKNTNKME 1380
NSGNSVSEII KPCSVNLIAS TSNDIENRAD GRVAVDKYGR DEKVSRRKAK RTYESGSESG 1440
DSDESESKSE QRTKRQPKPT YKKKQNDLQK RKGEVEEDSK PNGVLSRSAK DKSKLKLQNS 1500
NSAGVPRSVL KDWRKVKKLK QTGESFLQDD SCCEIGPNLQ KCRECRLIRS KKGEESTHSP 1560
VFCRFYYFRR LSFSKNGVVR IDGFSSPDQY DDEAMSLWTH ENYEDDEVDV ETSKYILDII 1620
GDKFCQLVTS EKTALSWVKK DAKIAWKRAV RGVREMCDAC EATLFNVHWV CRKCGFVACL 1680
DCYKAKERKS SRDKELYAWM KCVKGQPHDH KHLMLTQIIP GSVLTDLLDA MHILREKYGI 1740
KSHCHCTNRQ NLQGGNVPTM NGVSQVLQNV LHHSNKTSVS LPESQQQNSP QKSQTNGNSS 1800
PGSASTDSRL TPPESQSPLH WLADLAEQKS REEKQENKEF TLEREIKEDG DQDASDSPNG 1860
STSPPASQSN EQGSTLRDLL TTTAGKLRVG STDAGIAFAP VYSMGTSSGK GGRTMPNILD 1920
DIIASVVENK IPPNKTSKIN IKSEPNEEPK ESSLPATDES NKSYRDIPHS WICDQHILWL 1980
KDYKNSNNWK LFKECWKQGQ PAVVSGVHKK MNISLWKAES ISLDFGDHQA DLLNCKDSIV 2040
SNANVKEFWD GFEEVSKRQK NKGGETVVLK LKDCPSGEDF KAMMPTRYED FLRCLPLPEY 2100
CNPEGKFNLA SHLPGFFVRP DLGPRLCSAY GVAAAKDHDI GTTNLHIEAS DVVNVLVYVG 2160
IAKGNGVLSK AGILKKFEEE ELDDVLRKRL KDSSEIPGAL WHIYAGKDVD KIREFLQKIS 2220
KEQGLEVLPE HDPIRDQSWY VNRKLRQRLL EEYGVRACTL IQFLGDAIVL PAGTLHQVQN 2280
FHSCVQVTED FVSPEHLVQS FHLTQELRLL KEEINYDDKL QVKNILYHAV KEMVRALKMH 2340
EDEVEDMEDT
Nucleotide Sequence
(Fasta)		TTTGGGTGTC TGCGCTGTTG GAAGCAACTG CCGTGTGTTT CCATGCAGAC AGTACAGTGG 60
GAAAGCTTCC TCTAGCTAAT GGATGGCTGT TCTCTTTATT TGGAGTATCT TGCTGGTTAT 120
GTAAGCGACC TCGGGAGAAA TTATCCTGAC CCAGATCGGA GGATGCGGTA GTGCTTCAGC 180
TGCAGGATTT CTTCGTCGTT AACACCACAG TGCTGATGAC AAAGAGCAAG TTGTAATCCG 240
CAGCACTGCC AGGGCTGAGC CGGGCAGACA GAAAATCGTC ATTTGCTGCT CACAGGCTTG 300
TTAGGTTACA GCCTCTGCTT CGTTCTGTGG TCTTGGCTTT TCTTCCTATA CAATGACGGC 360
GCTGCAAGTG AGCTCAGAAA TGCTTGGTTT GAAAGCCATT TGCCTGTGAT TGTTTTTGAA 420
GACTAAAGAA GTATTTATGC TCGATTAAAA AAATACTGCT CACGAACAAA ATGAAATGCC 480
AGCTATATTT ACTGACCTTT AAAGCCTTGG CTTGGATTGC TGAGATTTAA AGATACTTTA 540
AAATTCTCAA GAACTAAGTA CGACCTTCAA ACCATTGGTT GAAAATAGTA TACCTAGTTC 600
TATCACTGCA GTAGAATTCC TTATAGATAA GCAACTGGAT TTTTTAACAG AAGATAGTGC 660
CTTTCAGCCA TACCAGGACG ACATAGACAG CTTAAAGCCC GTACTCAGGG ACAACCCACA 720
GCTGCACGCG GAAGTGAAAG TCTGGGTGAA GGAACAGAAG GTCCAGGAGA TTTTTATGCA 780
AGGTCCTTAT TCATTAAATG GATACAGAGT GAGAGTCTAT AGACAAGATT CTGCCACCCA 840
GTGGTTTACT GGCATAATTA CTCATCATGA TCTCTTCACC CGCACCATGA TCGTTATGAA 900
TGATCAGGTA CTAGAACCAC AGAATGTCGA TCCTTCTATG GTTCAAATGA CCTTTCTAGA 960
TGATGTCGTT CACTCTTTGT TAAAAGGTGA AAATATTGGC ATTACATCAC GGCGAAGGTC 1020
TCGTGCCAGT CAAAATATCA GCACTGTTCA CGGTCATTAT ACACGTGCTC AAGCAAATAG 1080
TCCCAGACCA GCAATGAACT CTCAAGCTGC TGTACCAAAA CAGAACACAC ACCAGCAACA 1140
GCAACAAAGA AGTATTCGTC CAAATAAGAG GAAGGGTTCA GATAGCAGCA TACCCGATGA 1200
AGAGAAGATG AAGGAAGATA AATATGATTG TGTATCACGA GGAGAAAATC CTAAAGGTAA 1260
GAACAAGCAC GTGGTGACAA AACGGCGGAA ACCTGAGGAG GCCGAGAAGA GGCTGAGCAT 1320
GAAAAGGCTC CGGACAGACA ATGCCTCTGA CGCCTCCGAG AGCAGTGACG CAGAGAGCTC 1380
CAGCAAGAGA GTGACTGAGA CTTCCTCCTC TGAACCAATG CCAGAGTATG AACCGAAAAA 1440
TAAAGTCACC TCAAAGGTAA ATGGAGAGGA GGGACAGTCC CAGGCTGCTG AAGAGGCAGG 1500
AGAAGAGACC CTGATAGATA CTCGGCCTCC CTGGGACCAG ATGCAGGAAG ATAAAAACCA 1560
CAACGAAGGG GAGAAGCCCA AGTCCACGGA CAGCCACCTT CAAGACAAAA TGACTCTCCG 1620
TTCATCTGAG CAAGCCACAG TTGCTGACCA CAATTCTAAT GATTCAGTCC TTCAAGAATG 1680
CAATGTGGAA AACCAACGCA CAGTGGAATT ATTACCAAAG GACAGGTTAG TGTCCAGAAC 1740
ACCGACACCC AAATGTGTTA CGGATATCAA GAACGACACT CATTCTGAGA GGGCGGCTCA 1800
GGAAAATTTA AATACTTTTG GCCTCCAGAC ACCTGAGAAC ATGGATCCAA ATGTTAGTGA 1860
TTCCAAACAT TCAAATGCTA AATACCTAGA AACAGCAAAG CAAGATTGTG ACCAGAGCTG 1920
GGTCAGTGAT GTAGTGAAAG TGGATTTAAC TCAGTCAAGT GTTACAAATG CTCCTTCAGG 1980
AAGTGATAAG CGCGATACGG AGAAAGAGAG AAATCACTAT GTCTCATACA TGTCTTCATT 2040
AAGTGCAGTT TCTGTCACAG AGGATCAGCT ACATAAACGA AGTCCACCCC CAGAAACTAT 2100
AAAAGCTAAA CTAACTACTT CAGTAGATAC CCAGAAGGCA AAATCCAGTT CTTCACCTGA 2160
AGTTGTTAAA CCCAAGATCA CTCATTCTCC TGATTCTGTG AAGTCTAAAG CTGCTTATGG 2220
GAACAGTCAA GCTGTTGGTG AGCGAAGGCT GGCAAATAAA ATAGAGCATG AGTTATCCAG 2280
AGGTAGTTTC CATCCAGTTC CTACTCGAGG CAGTGCTTTG GAAACTACAA AGAGCCCTCT 2340
TATCATTGAT AAAAACGAGC ACTTCACAGT CTATAGGGAT CCTGCTCTTA TTGGATCAGA 2400
AACAGGAGCT AATCACATTT CACCTTTTTT GAGCCAGCAT CCTTTTTCTC TTCATTCCTC 2460
ATCCCATAGA ACCTGTTTAA ACCCAGGTAC CCATCACCCT GCCTTAACGC CAGGACCCCA 2520
CTTACTAGCT GGGTCAACTA GTCAAACTCC ATTACCTACC ATTAACACTC ACCCTCTCAC 2580
TAGTGGTCCA CACCATCCTG TCCATCACCC TCATTTGCTT CCCACTGTGT TACCTGGAGT 2640
GCCTACTGCC TCTTTACTCG GTGGCCACCC ACGTCTAGAG AGTGCTCATG CAAGCAGCTT 2700
GAGCCATTTA GCACTAGCAC ACCAGCAGCA GCAACAGTTG TTACAGCACC AGTCACCTCA 2760
TCTTCTTGGA CAAGCCCATC CTTCCGCTTC ATATAATCAG CTTGGACTTT ATCCAATTAT 2820
TTGGCAATAT CCGAATGGAA CACATGCATA CTCAGGACTT GGTCTCCCTT CTTCTAAGTG 2880
GGTTCACCCA GAAAATGCAG TTAATGCTGA AGCTTCATTA AGGAGGAATT CTCCCAGTCC 2940
TTGGCTACAT CAACCCACTC CTGTGACCTC AGCGGATGGT ATTGGATTAC TTAGTCACAT 3000
TCCTGTCAGA CCTTCCAGTG CAGAGCCTCA TCGACCTCAC AAGATTACAG TGCATTCCAG 3060
TCCCCCACTG ACAAAGACAT TAGCAGATCA CCACAAAGAA GAATTGGAGA GGAAAGCTTT 3120
TATGGAACCA TTACGGTCTA ATGCATCCAC ATCAGTAAAA GGTGACCTGG ATCTTAATAG 3180
GTCACAGGCA GGAAAAGATT GTCACTTGCA TAGGCATTTT GTGGGTCCAA GGCCACCCCA 3240
GGAGACTGGA GAGAGACTGA ACAAATACAA GGAGGAACAT CGTCGGATTC TTCAGGAGAG 3300
TATTGATGTG GCTCCATTTA CAACCAAAAT CAAGGGTCAT GAGGTTGAAA GAGAGAATTA 3360
CTCCAGAGTA GTACCATCAT CTTCTAGTCC TAAAAGCCAT GCTATCAAAC AAGATAAAGA 3420
CGTAGACCGC TCCGTGTCAG AGATTTATAA GATGAAGCAC TCAGTGCCTC AGAGTTTGCC 3480
CCAGAGTAAC TACTTCACTA CTTTATCTAA TAGTGTGGTC AATGAGCCAC CAAGATCCTA 3540
CCCATCCAAA GAAGTTTCCA ACATTTACAC TGAGAAACAA AATAATAACC TTTCTGCAAC 3600
AGCCAATCCT CAAACTCATT CTTTTATATC ATCTCTTTCG AAGCCTCCAC CTTTGATTAA 3660
ACACCAACCA GAAAGTGAAA GTTTAGTGGG CAAGATACCA GACCATCTTC CCCATCAGAG 3720
TGCATCTCAC TCAGTAACAA CGTTCAGAAG TGATTGTCGG AGCCCTACCC ATCTGACTGT 3780
TTCTTCTACT AATGCACTCC GCAGCATGCC TGCTCTGCAC AGGGCACCAG TATTCCATCC 3840
ACCAATCCAC CACAGTTTGG AAAGAAAGGA AAGCAGCTAC AGTAGCCTTT CCCCTCCAAC 3900
ACTGACACCG GTGATGCCAG TAAATGCTGG TGGCAAAGTT CAAGAATCTC AGAAGCCTCC 3960
AACTCTAATT CCTGAGCCAA AAGACTCTCA GTCAAATTTT AAGAATTCTT CTGATCAGAG 4020
TCTAACGGAA ATGTGGAGAT CTAATAACAA CCTCAACAGA GAGAAAGCTG AGTGGCCCGT 4080
GGAAAAGAGT AGTGGAAAGT CCCAGGCTGC TGTGGCATCT GTCATTGTTC GTCCACCTTC 4140
TAGTACAAAA GTTGATAGTG TGCCATCTGT ACCATTAGCT TCCAAAGATC GAGTTTGTGA 4200
AAGATCTTCA TCTGGGGCAA ATAAAACAGA TTACCTCAAA CCAGAAGCCG GAGAGACTGG 4260
AAGAATTATT CTACCAAATG TGAATTTAGA AAGTGCTCAT GTGAAATCTG AAAAAAACTT 4320
TGAAGCTGTC TCCCAGGGCA ACGTTCCTGT TTCAGTCATG TCTGCTGTAA ATGTAGTCTC 4380
TACTACCAAA GCAGATGTGT TCACATCTGC TGCCACTACC ACCAGTGTCT CCAGCTTGAG 4440
TAGTGCAGAA ACAAGTTATT CTTTATCAAA TACCATTTCG GCCTCTACAC CCTTCGAATG 4500
TACTTCTTCA AAAAGTGTTG TTAGTCAGGC AGTGGCGCAA GCAAAGGACT GCACAGTCAG 4560
CACCGCGGTT CCAGGCACTC TGGCCTGTAG TAAGACAGGA AGTGCTGTTC AGCCCGGCTC 4620
TGGCTTCTCA GGCACAACTG ATTTTATTCA TTTAAAAAAG CACAAGGCAG CGTTGGCTGC 4680
AGCTCAGTTT AAAAATAGTA GTGTCAGTGA GGCTGAACTT AATACTGTGA GAAATCAGAC 4740
AGTGGCAGCC TCTCTTCCCC TGGATAGCAC CATGACCTGC ACTGCAAGTA ACAAAGCAAT 4800
CTCTGTAGGA AATGGGCCAG CAGCCCAGTC CAGTCAGCCC AACTACCACA CTAAACTGAA 4860
GAAGGCCTGG CTCACCAGAC ATTCAGAAGA AGATAAAAAT ACTAATAAAA TGGAAAATTC 4920
AGGGAATTCT GTATCCGAAA TTATTAAGCC ATGTTCTGTC AACTTAATAG CCTCTACATC 4980
TAATGATATA GAAAATCGTG CAGATGGCAG AGTCGCTGTA GATAAATATG GAAGAGATGA 5040
GAAAGTCAGC AGGAGAAAAG CCAAAAGAAC TTACGAATCT GGCTCTGAAA GTGGAGACTC 5100
AGATGAGAGC GAAAGCAAGT CGGAGCAGAG GACTAAACGG CAGCCGAAGC CAACTTATAA 5160
AAAGAAGCAG AACGACCTGC AGAAGAGGAA AGGCGAGGTC GAAGAGGACT CGAAGCCTAA 5220
TGGAGTTCTC AGCAGGAGCG CCAAGGACAA AAGTAAACTG AAGTTGCAGA ACAGTAATAG 5280
CGCTGGCGTT CCTCGTTCCG TGCTGAAAGA CTGGCGGAAG GTCAAGAAGC TGAAGCAAAC 5340
TGGAGAATCA TTTCTGCAGG ATGACTCCTG CTGTGAGATA GGTCCCAACT TACAGAAGTG 5400
CCGAGAGTGC AGACTTATCC GGAGTAAGAA GGGGGAAGAA TCAACTCACT CACCGGTGTT 5460
TTGTAGATTT TACTACTTTA GGAGATTGTC CTTTAGTAAG AATGGAGTAG TCAGAATAGA 5520
TGGTTTCTCT TCTCCTGATC AATACGATGA TGAAGCCATG AGTTTATGGA CCCATGAAAA 5580
TTATGAAGAT GATGAAGTAG ATGTTGAAAC CTCTAAGTAT ATCTTGGACA TAATAGGTGA 5640
TAAGTTCTGT CAGTTAGTAA CGTCTGAGAA AACAGCGTTG TCCTGGGTGA AAAAGGATGC 5700
CAAAATTGCA TGGAAAAGGG CAGTTCGAGG TGTCCGGGAG ATGTGTGATG CGTGCGAGGC 5760
CACACTGTTC AACGTCCACT GGGTTTGCCG CAAGTGTGGA TTTGTGGCTT GCTTGGACTG 5820
TTACAAGGCC AAGGAAAGGA AGAGTTCTAG AGATAAAGAG CTGTATGCTT GGATGAAGTG 5880
TGTGAAAGGC CAGCCCCATG ACCATAAGCA TCTGATGCTG ACTCAGATTA TCCCTGGCTC 5940
TGTGTTGACA GACCTTCTTG ATGCCATGCA CATTCTTAGG GAAAAATATG GTATTAAATC 6000
CCATTGTCAC TGTACAAACA GACAGAATTT ACAAGGTGGA AATGTTCCTA CAATGAATGG 6060
TGTGTCTCAA GTTCTACAGA ATGTTCTTCA CCACAGTAAT AAGACTTCTG TGTCCCTGCC 6120
TGAGTCTCAG CAGCAGAACA GCCCTCAGAA ATCTCAGACT AACGGCAACA GTAGCCCTGG 6180
AAGTGCAAGT ACAGACAGCA GGTTGACACC TCCAGAGTCC CAGTCACCGC TGCACTGGCT 6240
AGCTGATCTT GCTGAGCAGA AATCCAGAGA GGAAAAACAA GAAAACAAAG AATTTACTCT 6300
TGAAAGGGAA ATCAAAGAAG ATGGAGACCA AGATGCCTCT GATTCTCCAA ATGGCAGCAC 6360
ATCACCTCCA GCATCCCAGA GCAACGAACA GGGTTCAACC CTACGTGATT TGCTGACCAC 6420
AACAGCTGGC AAGCTTCGTG TGGGCTCTAC AGATGCTGGC ATTGCCTTTG CGCCAGTATA 6480
TTCAATGGGA ACCTCAAGTG GCAAAGGTGG CCGGACTATG CCTAACATTC TTGATGACAT 6540
CATTGCTTCA GTTGTTGAAA ACAAAATTCC ACCAAATAAA ACCTCCAAGA TCAATATAAA 6600
ATCAGAACCT AATGAAGAAC CCAAAGAAAG CAGTCTGCCT GCCACGGATG AAAGCAATAA 6660
GTCTTATCGT GACATACCAC ATTCTTGGAT CTGTGACCAG CATATTTTAT GGCTTAAAGA 6720
TTACAAGAAT AGTAATAACT GGAAGCTTTT CAAAGAGTGC TGGAAACAAG GACAGCCTGC 6780
AGTGGTTTCC GGTGTGCATA AGAAAATGAA CATTAGCTTG TGGAAGGCAG AATCAATTAG 6840
TCTGGATTTT GGAGACCACC AAGCTGATCT CCTCAACTGC AAAGACAGCA TTGTTTCCAA 6900
TGCCAACGTT AAGGAGTTCT GGGATGGTTT TGAAGAAGTG TCAAAACGTC AAAAAAACAA 6960
AGGTGGAGAA ACAGTAGTAT TAAAGTTGAA AGACTGCCCA TCTGGGGAGG ACTTCAAGGC 7020
CATGATGCCA ACAAGATATG AAGACTTTTT AAGATGTCTG CCATTACCAG AATATTGCAA 7080
CCCAGAAGGG AAGTTCAATT TGGCCTCCCA TTTGCCAGGG TTCTTTGTAC GCCCTGATCT 7140
AGGACCCAGG CTGTGCAGTG CCTATGGTGT TGCTGCTGCT AAGGATCATG ATATAGGAAC 7200
CACAAATCTT CACATTGAAG CTTCTGATGT TGTCAATGTC CTAGTCTATG TCGGCATAGC 7260
AAAAGGAAAT GGCGTCCTCT CAAAAGCAGG AATACTTAAG AAATTTGAAG AAGAAGAATT 7320
AGATGATGTT TTAAGAAAAA GATTAAAGGA TTCGAGTGAA ATCCCTGGTG CTCTATGGCA 7380
TATTTATGCT GGAAAAGATG TTGACAAGAT AAGGGAATTT CTTCAAAAGA TTTCAAAAGA 7440
ACAAGGCCTT GAAGTTCTGC CAGAGCATGA TCCAATCCGG GACCAAAGCT GGTATGTGAA 7500
TAGAAAGCTC CGCCAGAGAC TGCTTGAGGA ATATGGGGTG AGAGCCTGCA CTCTGATTCA 7560
GTTCCTTGGT GATGCCATTG TTTTGCCAGC AGGAACACTT CACCAGGTAC AAAATTTTCA 7620
CAGCTGTGTT CAGGTGACCG AAGACTTTGT CTCTCCAGAA CATCTTGTAC AGTCGTTTCA 7680
CTTAACACAG GAGCTGAGGC TTTTGAAGGA AGAAATCAAT TACGATGATA AACTCCAGGT 7740
TAAGAATATC TTGTATCATG CAGTCAAGGA AATGGTGAGA GCTCTGAAGA TGCATGAAGA 7800
TGAAGTAGAG GATATGGAAG ACACCTAATT GCGGTTGGAA CTGGGATGCC CCTTGAGTGA 7860
CGCTAGGTCT GACTTAAGCT CCATTAAACC ATCAGTGCCA AGAAATTCTC TTTGTAGTAA 7920
TTACTTGCTA CTGACACCAT ACCAGTATAG CATTATGCCA CAGCCCCTGT GATTCAATGC 7980
TAGCTATAAA CCAAGCTAAA TTTAAAAGCA GTACTATATA GCTGTTCCTG TATCATAGTG 8040
TATATGATGT TTGTGAAGAT GCCAGATTTA AAATGATGTA TTTATTTTTG GTAAAAAAAA 8100
AAATCTATGC TATATTGTTG ATCAAGTGTA AATGTGCTGT TGTACAGTTT AATAAAATAA 8160
CTGATATTTT TCACTACATT GAGACAGTTA CTGTGAGACT AGGACACACC AGCTGTTGCC 8220
TGCGTTTGGG AAATTGCTGG ATTGCACAGC AGTCACGTCA TAATCAGAAA ATTACTGCCA 8280
AATAATTGTA AAATGTGTAA AATACAAAGT ACATAAAGTA GATACTAAAC TCAGACACTT 8340
CAATATTTTG TTGAAGCTAT TGACTGTACA ATTAAACGTT TTCAAAAGGT GTAATTTATT 8400
TAAAATTGTC TCATTTTGGT AAAATTTATG TGAAGTTTTA AAGCTAAATA TTAAACTTAA 8460
TATGCTATGT AAATATATAC ATATATACAT TTAAGGATGT ATTTTTTTAA AACATTGGCT 8520
TGCTTTTGTT AAAGTGCAAG TGTTACATAT GGCTTTGTAC ATTACAGTTG AAAGGGGTTT 8580
TACATTTTCC ATTAAAAGAC TTTATCAAG
Sequence Source Ensembl
Keyword

KW-0156--Chromatin regulator
KW-0181--Complete proteome
KW-0223--Dioxygenase
KW-0903--Direct protein sequencing
KW-0408--Iron
KW-0479--Metal-binding
KW-0539--Nucleus
KW-0560--Oxidoreductase
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0804--Transcription
KW-0805--Transcription regulation
KW-0862--Zinc
KW-0863--Zinc-finger
--
Interpro

IPR003347--JmjC_dom
PROSITE

PS51184--JMJC
Pfam

PF02373--JmjC
Gene Ontology

GO:0005634--C:nucleus
GO:0051213--F:dioxygenase activity
GO:0046872--F:metal ion binding
GO:0016568--P:chromatin modification
GO:0003382--P:epithelial cell morphogenesis
GO:0098727--P:maintenance of cell number
GO:0036098--P:male germ-line stem cell population maintenance
GO:0008584--P:male gonad development
GO:0006355--P:regulation of transcription, DNA-templated
GO:1990636--P:reproductive senescence
GO:0072520--P:seminiferous tubule development
GO:0006351--P:transcription, DNA-templated
Orthology
WERAM ID Ensembl Protein ID Species Identity E-value Score
WERAM-Ran-0007 ENSRNOP00000000804.6 Rattus norvegicus 91 0.0 4019
WERAM-Aim-0103 ENSAMEP00000010062.1 Ailuropoda melanoleuca 85 0.0 3749
WERAM-Poa-0025 ENSPPYP00000002793.1 Pongo abelii 86 0.0 3748
WERAM-Otg-0151 ENSOGAP00000012868.2 Otolemur garnettii 85 0.0 3747
WERAM-Nol-0130 ENSNLEP00000014658.1 Nomascus leucogenys 86 0.0 3745
WERAM-Pat-0019 ENSPTRP00000004380.4 Pan troglodytes 86 0.0 3741
WERAM-Paa-0167 ENSPANP00000020474.1 Papio anubis 85 0.0 3739
WERAM-Caj-0082 ENSCJAP00000013430.1 Callithrix jacchus 85 0.0 3737
WERAM-Gog-0171 ENSGGOP00000015323.2 Gorilla gorilla 85 0.0 3732
WERAM-Caf-0138 ENSCAFP00000019288.3 Canis familiaris 85 0.0 3723
WERAM-Orc-0063 ENSOCUP00000005987.3 Oryctolagus cuniculus 85 0.0 3720
WERAM-Fec-0091 ENSFCAP00000007544.3 Felis catus 85 0.0 3716
WERAM-Mup-0126 ENSMPUP00000011032.1 Mustela putorius furo 85 0.0 3712
WERAM-Bot-0015 ENSBTAP00000002067.5 Bos taurus 84 0.0 3691
WERAM-Ova-0037 ENSOARP00000004931.1 Ovis aries 84 0.0 3689
WERAM-Sus-0072 ENSSSCP00000010901.2 Sus scrofa 85 0.0 3671
WERAM-Loa-0019 ENSLAFP00000001234.4 Loxodonta africana 84 0.0 3660
WERAM-Myl-0200 ENSMLUP00000019481.1 Myotis lucifugus 84 0.0 3645
WERAM-Eqc-0089 ENSECAP00000010951.1 Equus caballus 83 0.0 3643
WERAM-Cap-0153 ENSCPOP00000012777.2 Cavia porcellus 84 0.0 3607
WERAM-Ptv-0190 ENSPVAP00000016931.1 Pteropus vampyrus 81 0.0 3421
WERAM-Ora-0123 ENSOANP00000024031.2 Ornithorhynchus anatinus 77 0.0 3331
WERAM-Dan-0123 ENSDNOP00000016821.2 Dasypus novemcinctus 76 0.0 3308
WERAM-Soa-0109 ENSSARP00000010281.1 Sorex araneus 83 0.0 3234
WERAM-Anp-0097 ENSAPLP00000011260.1 Anas platyrhynchos 75 0.0 3232
WERAM-Gaga-0028 ENSGALP00000004639.4 Gallus gallus 74 0.0 3190
WERAM-Mod-0154 ENSMODP00000021455.4 Monodelphis domestica 74 0.0 3148
WERAM-Fia-0163 ENSFALP00000013846.1 Ficedula albicollis 72 0.0 3139
WERAM-Meg-0116 ENSMGAP00000012206.2 Meleagris gallopavo 73 0.0 3131
WERAM-Pes-0084 ENSPSIP00000010379.1 Pelodiscus sinensis 72 0.0 3125
WERAM-Ect-0040 ENSETEP00000003644.1 Echinops telfairi 81 0.0 3066
WERAM-Anc-0107 ENSACAP00000010106.3 Anolis carolinensis 68 0.0 2848
WERAM-Sah-0033 ENSSHAP00000003926.1 Sarcophilus harrisii 65 0.0 2728
WERAM-Vip-0090 ENSVPAP00000008193.1 Vicugna pacos 85 0.0 2700
WERAM-Lac-0106 ENSLACP00000013167.1 Latimeria chalumnae 63 0.0 2625
WERAM-Xet-0053 ENSXETP00000016739.3 Xenopus tropicalis 63 0.0 2585
WERAM-Chh-0067 ENSCHOP00000007325.1 Choloepus hoffmanni 80 0.0 2545
WERAM-Leo-0064 ENSLOCP00000008323.1 Lepisosteus oculatus 59 0.0 2493
WERAM-Dio-0141 ENSDORP00000013126.1 Dipodomys ordii 82 0.0 2199
WERAM-Prc-0100 ENSPCAP00000009289.1 Procavia capensis 75 0.0 2155
WERAM-Tas-0048 ENSTSYP00000004523.1 Tarsius syrichta 82 0.0 1818
WERAM-Tut-0085 ENSTTRP00000006797.1 Tursiops truncatus 90 0.0 1732
WERAM-Gaa-0164 ENSGACP00000020266.2 Gasterosteus aculeatus 50 0.0 1615
WERAM-Ere-0124 ENSEEUP00000013255.1 Erinaceus europaeus 77 0.0 1526
WERAM-Asm-0121 ENSAMXP00000012322.1 Astyanax mexicanus 69 0.0 1429
WERAM-Dar-0185 ENSDARP00000140909.1 Danio rerio 68 0.0 1422
WERAM-Orn-0082 ENSONIP00000009123.1 Oreochromis niloticus 66 0.0 1362
WERAM-Xim-0176 ENSXMAP00000014219.1 Xiphophorus maculatus 63 0.0 1312
WERAM-Gam-0134 ENSGMOP00000013905.1 Gadus morhua 62 0.0 1289
WERAM-Pof-0105 ENSPFOP00000009100.2 Poecilia formosa 59 0.0 1283
WERAM-Ten-0055 ENSTNIP00000007322.1 Tetraodon nigroviridis 62 0.0 1234
WERAM-Mim-0085 ENSMICP00000007975.1 Microcebus murinus 85 0.0 1117
WERAM-Mam-0167 ENSMMUP00000023314.2 Macaca mulatta 87 0.0 1086
WERAM-Hos-0199 ENSP00000335929.5 Homo sapiens 87 0.0 1079
WERAM-Tub-0089 ENSTBEP00000010148.1 Tupaia belangeri 79 0.0 1035
WERAM-Ocp-0069 ENSOPRP00000006015.2 Ochotona princeps 78 0.0 959
WERAM-Tag-0001 ENSTGUP00000000018.1 Taeniopygia guttata 48 0.0 836
WERAM-Chs-0157 ENSCSAP00000009298.1 Chlorocebus sabaeus 48 0.0 834
WERAM-Pem-0103 ENSPMAP00000010459.1 Petromyzon marinus 46 0.0 830
WERAM-Mae-0023 ENSMEUP00000001666.1 Macropus eugenii 46 0.0 801
WERAM-Tar-0009 ENSTRUP00000002076.1 Takifugu rubripes 45 0.0 799
WERAM-Orla-0053 ENSORLP00000006841.1 Oryzias latipes 44 0.0 797
WERAM-Ict-0030 ENSSTOP00000002342.2 Ictidomys tridecemlineatus 44 0.0 721
WERAM-Drm-0063 FBpp0081541 Drosophila melanogaster 45 1e-100 366
WERAM-Cii-0009 ENSCINP00000003397.3 Ciona intestinalis 45 2e-94 346
WERAM-Cis-0016 ENSCSAVP00000003200.1 Ciona savignyi 44 7e-86 317
WERAM-Met-0034 AES62949 Medicago truncatula 35 1e-48 194
WERAM-Brr-0149 Bra029664.1-P Brassica rapa 33 1e-46 187
WERAM-Arl-0071 fgenesh2_kg.3__ 790__ AT3G07610.1 Arabidopsis lyrata 32 1e-45 184
WERAM-Sot-0046 PGSC0003DMT400042379 Solanum tuberosum 32 2e-45 183
WERAM-Bro-0103 Bo5g141320.1 Brassica oleracea 32 2e-44 180
WERAM-Glm-0193 GLYMA15G11770.2 Glycine max 31 4e-44 179
WERAM-Art-0066 AT3G07610.1 Arabidopsis thaliana 33 8e-44 178
WERAM-Spr-0032 CBQ68647 Sporisorium reilianum 31 6e-42 172
WERAM-Sol-0031 Solyc02g082400.2.1 Solanum lycopersicum 31 9e-42 171
WERAM-Lab-0028 EDR05015 Laccaria bicolor 29 1e-41 171
WERAM-Viv-0067 VIT_10s0116g00960.t01 Vitis vinifera 29 7e-40 165
WERAM-Brd-0109 BRADI4G29617.1 Brachypodium distachyon 30 9e-40 164
WERAM-Thc-0088 EOY14163 Theobroma cacao 31 9e-40 164
WERAM-Crn-0005 AAW41444 Cryptococcus neoformans 30 2e-39 163
WERAM-Sei-0105 Si028936m Setaria italica 31 2e-39 163
WERAM-Lep-0100 LPERR09G06290.1 Leersia perrieri 30 3e-39 162
WERAM-Zem-0051 GRMZM2G070885_P01 Zea mays 29 6e-39 161
WERAM-Pot-0063 POPTR_0005s09360.1 Populus trichocarpa 34 2e-38 160
WERAM-Sob-0029 Sb02g024010.1 Sorghum bicolor 29 6e-38 158
WERAM-Orm-0094 OMERI09G07170.1 Oryza meridionalis 28 2e-36 154
WERAM-Aet-0048 EMT13865 Aegilops tauschii 29 5e-36 152
Created Date 25-Jun-2016