| Tag |
Content |
| WERAM ID |
WERAM-Mum-0101 |
| Ensembl Protein ID |
ENSMUSP00000080419.6 |
| Uniprot Accession |
Q61188; EZH2_MOUSE; Q99L74; Q9R090
|
| Genbank Protein ID |
NP_031997.2
|
| Protein Name |
Histone-lysine N-methyltransferase EZH2 |
| Genbank Nucleotide ID |
NM_007971.2
|
| Gene Name |
EZH2 |
| Ensembl Information |
|
| Details |
| Type |
Family |
Domain |
Substrates |
AA |
References (PMIDs) |
| HMT |
SET1 |
SET |
H3K9; H3K27 |
K |
19026780
|
|
| Status |
Reviewed |
| Classification |
| Type |
Family |
E-value |
Score |
Start |
End |
| HMT |
EZ |
4.10e-63 |
212.1 |
612 |
727 |
| HMT |
SET1 |
2.30e-42 |
145.3 |
612 |
727 |
|
| Organism |
Mus musculus |
| NCBI Taxa ID |
10090 |
Functional Description
(View)Functional Description
Polycomb group (PcG) protein. Catalytic subunit of the PRC2/EED-EZH2 complex, which methylates (H3K9me) and 'Lys-27' (H3K27me) of histone H3, leading to transcriptional repression of the affected target gene. Able to mono-, di- and trimethylate 'Lys-27' of histone H3 to form H3K27me1, H3K27me2 and H3K27me3, respectively. Compared to EZH2-containing complexes, it is more abundant in embryonic stem cells and plays a major role in forming H3K27me3, which is required for embryonic stem cell identity and proper differentiation. The PRC2/EED-EZH2 complex may also serve as a recruiting platform for DNA methyltransferases, thereby linking two epigenetic repression systems. Genes repressed by the PRC2/EED-EZH2 complex include HOXA7, HOXB6 and HOXC8. EZH2 can also methylate non-histone proteins such as the transcription factor GATA4 and the nuclear receptor RORA. Regulates the circadian clock via histone methylation at the promoter of the circadian genes. Essential for the CRY1/2-mediated repression of the transcriptional activation of PER1/2 by the CLOCK-ARNTL/BMAL1 heterodimer; involved in the di and trimethylation of 'Lys-27' of histone H3 on PER1/2 promoters which is necessary for the CRY1/2 proteins to inhibit transcription. |
Polycomb group (PcG) protein. Catalytic subunit of the PRC2/EED-EZH2 complex, which methylates (H3K9me) and 'Lys-27' (H3K27me) of histone H3, leading to transcriptional repression of the affected target gene. Able to mono-, di- and trimethylate 'Lys-27' of histone H3 to form H3K27me1, H3K27me2 and H3K27me3, respectively. Compared to EZH2-containing complexes, it is more abundant in embryonic stem cells and plays a major role in forming H3K27me3, which is required for embryonic stem cell identity and proper differentiation. The PRC2/EED-EZH2 complex may also serve as a recruiting platform for DNA methyltransferases, thereby linking two epigenetic repression systems. Genes repressed by the PRC2/EED-EZH2 complex include HOXA7, HOXB6 and HOXC8. EZH2 can also methylate non-histone proteins such as the transcription factor GATA4 and the nuclear receptor RORA. Regulates the circadian clock via histone methylation at the promoter of the circadian genes. Essential for the CRY1/2-mediated repression of the transcriptional activation of PER1/2 by the CLOCK-ARNTL/BMAL1 heterodimer; involved in the di and trimethylation of 'Lys-27' of histone H3 on PER1/2 promoters which is necessary for the CRY1/2 proteins to inhibit transcription.
|
| Domain Profile |
HMT EZ
EZ.txt 1 krillgksdvaGwGlflkesvekneylgeytGelisddeadkrGkiydrakssflfnlndqlvidakrkGnklkfanhsakpncyakvl 89
k++ll++sdvaGwG+f+k++v+kne+++ey+Ge+is+dead+rGk+yd++++sflfnln+++v+da+rkGnk++fanhs +pncyakv+
ENSMUSP00000080419.6 612 KHLLLAPSDVAGWGIFIKDPVQKNEFISEYCGEIISQDEADRRGKVYDKYMCSFLFNLNNDFVVDATRKGNKIRFANHSVNPNCYAKVM 700
789************************************************************************************** PP
EZ.txt 90 lvaGdhriGlfakrrieaseelffdyr 116
+v+GdhriG+fakr+i+++eelffdyr
ENSMUSP00000080419.6 701 MVNGDHRIGIFAKRAIQTGEELFFDYR 727
**************************7 PP
HMT SET1
SET1.txt 1 kelevakskikglglvakkeiekeelviEYvGevirsevadkrekeyekkeigvylfrldedaevvvdatkkgniarfinhscepNcea 89
k+l +a s+++g+g+++k++++k+e++ EY+Ge+i++++ad+r k y+k+ + ++lf+l++d +vvdat+kgn++rf nhs++pNc+a
ENSMUSP00000080419.6 612 KHLLLAPSDVAGWGIFIKDPVQKNEFISEYCGEIISQDEADRRGKVYDKY-MCSFLFNLNND--FVVDATRKGNKIRFANHSVNPNCYA 697
678999*******************************************9.456********..************************* PP
SET1.txt 90 kvvavdgekkiviyakraIekgeeltydYk 119
kv++v+g+++i+i+akraI++geel++dY+
ENSMUSP00000080419.6 698 KVMMVNGDHRIGIFAKRAIQTGEELFFDYR 727
*****************************6 PP
|
Protein Sequence
(Fasta) | MGQTGKKSEK GPVCWRKRVK SEYMRLRQLK RFRRADEVKT MFSSNRQKIL ERTETLNQEW 60
KQRRIQPVHI MTSVSSLRGT RECSVTSDLD FPAQVIPLKT LNAVASVPIM YSWSPLQQNF 120
MVEDETVLHN IPYMGDEVLD QDGTFIEELI KNYDGKVHGD RECGFINDEI FVELVNALGQ 180
YNDDDDDDDG DDPDEREEKQ KDLEDNRDDK ETCPPRKFPA DKIFEAISSM FPDKGTAEEL 240
KEKYKELTEQ QLPGALPPEC TPNIDGPNAK SVQREQSLHS FHTLFCRRCF KYDCFLHPFH 300
ATPNTYKRKN TETALDNKPC GPQCYQHLEG AKEFAAALTA ERIKTPPKRP GGRRRGRLPN 360
NSSRPSTPTI SVLESKDTDS DREAGTETGG ENNDKEEEEK KDETSSSSEA NSRCQTPIKM 420
KPNIEPPENV EWSGAEASMF RVLIGTYYDN FCAIARLIGT KTCRQVYEFR VKESSIIAPV 480
PTEDVDTPPR KKKRKHRLWA AHCRKIQLKK DGSSNHVYNY QPCDHPRQPC DSSCPCVIAQ 540
NFCEKFCQCS SECQNRFPGC RCKAQCNTKQ CPCYLAVREC DPDLCLTCGA ADHWDSKNVS 600
CKNCSIQRGS KKHLLLAPSD VAGWGIFIKD PVQKNEFISE YCGEIISQDE ADRRGKVYDK 660
YMCSFLFNLN NDFVVDATRK GNKIRFANHS VNPNCYAKVM MVNGDHRIGI FAKRAIQTGE 720
ELFFDYRYSQ ADALKYVGIE REMEIP 746Protein Fasta Sequence
>ENSMUSP00000080419.6|EZH2|Mus musculus
MGQTGKKSEKGPVCWRKRVKSEYMRLRQLKRFRRADEVKTMFSSNRQKILERTETLNQEWKQRRIQPVHIMTSVSSLRGTRECSVTSDLDFPAQVIPLKTLNAVASVPIMYSWSPLQQNFMVEDETVLHNIPYMGDEVLDQDGTFIEELIKNYDGKVHGDRECGFINDEIFVELVNALGQYNDDDDDDDGDDPDEREEKQKDLEDNRDDKETCPPRKFPADKIFEAISSMFPDKGTAEELKEKYKELTEQQLPGALPPECTPNIDGPNAKSVQREQSLHSFHTLFCRRCFKYDCFLHPFHATPNTYKRKNTETALDNKPCGPQCYQHLEGAKEFAAALTAERIKTPPKRPGGRRRGRLPNNSSRPSTPTISVLESKDTDSDREAGTETGGENNDKEEEEKKDETSSSSEANSRCQTPIKMKPNIEPPENVEWSGAEASMFRVLIGTYYDNFCAIARLIGTKTCRQVYEFRVKESSIIAPVPTEDVDTPPRKKKRKHRLWAAHCRKIQLKKDGSSNHVYNYQPCDHPRQPCDSSCPCVIAQNFCEKFCQCSSECQNRFPGCRCKAQCNTKQCPCYLAVRECDPDLCLTCGAADHWDSKNVSCKNCSIQRGSKKHLLLAPSDVAGWGIFIKDPVQKNEFISEYCGEIISQDEADRRGKVYDKYMCSFLFNLNNDFVVDATRKGNKIRFANHSVNPNCYAKVMMVNGDHRIGIFAKRAIQTGEELFFDYRYSQADALKYVGIEREMEIP |
Nucleotide Sequence
(Fasta) | GCGTTTGGCG CTCGGTCCGG TCGCGTCCGA CACCCAGTGG GACATCGAAG GCAGTGGAGT 60
CCCGGCGGCG GCGGTGGCGG TGGCGGCGGG TTGGGGGCGA CGCGCGGGAG AGGCGCGGGC 120
TGGCGCGCGG GACGAAGAAT AATCATGGGC CAGACTGGGA AGAAATCTGA GAAGGGACCG 180
GTTTGTTGGC GGAAGCGTGT AAAATCAGAG TACATGAGAC TGAGACAGCT CAAGAGGTTC 240
AGAAGAGCTG ATGAAGTAAA GACTATGTTT AGTTCCAATC GTCAGAAAAT TTTGGAAAGA 300
ACTGAAACCT TAAACCAAGA GTGGAAGCAG CGGAGGATAC AGCCTGTGCA CATCATGACT 360
TCTGTGAGCT CATTGCGCGG GACTAGGGAG TGTTCAGTCA CCAGTGACTT GGATTTTCCA 420
GCACAAGTCA TCCCGTTAAA GACCCTGAAT GCAGTCGCCT CGGTGCCTAT AATGTACTCT 480
TGGTCGCCCT TACAACAGAA TTTTATGGTG GAAGACGAAA CTGTTTTACA TAACATTCCT 540
TATATGGGGG ATGAAGTTCT GGATCAGGAT GGCACTTTCA TTGAAGAACT AATAAAAAAT 600
TATGATGGAA AAGTGCATGG TGACAGAGAA TGTGGATTTA TAAATGATGA AATTTTTGTG 660
GAGTTGGTAA ATGCTCTTGG TCAATATAAT GATGATGATG ATGACGATGA TGGAGATGAT 720
CCAGATGAAA GAGAAGAAAA ACAGAAAGAT CTAGAGGATA ATCGAGATGA TAAAGAAACT 780
TGCCCACCTC GGAAATTTCC TGCTGATAAA ATATTTGAAG CCATTTCCTC AATGTTTCCA 840
GATAAGGGCA CCGCAGAAGA ACTGAAAGAA AAATATAAAG AACTCACGGA GCAGCAGCTC 900
CCAGGTGCTC TGCCTCCTGA ATGTACTCCA AACATCGATG GACCAAATGC CAAATCTGTT 960
CAGAGGGAGC AAAGCTTGCA TTCATTTCAT ACGCTCTTCT GTCGACGATG TTTTAAGTAT 1020
GACTGCTTCC TACATCCCTT CCATGCAACA CCCAACACAT ATAAGAGGAA GAACACAGAA 1080
ACAGCTTTGG ACAACAAGCC TTGTGGACCA CAGTGTTACC AGCATCTGGA GGGAGCTAAG 1140
GAGTTTGCTG CTGCTCTTAC TGCTGAGCGT ATAAAGACAC CACCTAAACG CCCAGGGGGC 1200
CGCAGAAGAG GAAGACTTCC GAATAACAGT AGCAGACCCA GCACCCCCAC CATCAGTGTG 1260
CTGGAGTCAA AGGATACAGA CAGTGACAGA GAAGCAGGGA CTGAAACTGG GGGAGAGAAC 1320
AATGATAAAG AAGAAGAAGA GAAAAAAGAT GAGACGTCCA GCTCCTCTGA AGCAAATTCT 1380
CGGTGTCAAA CACCAATAAA GATGAAGCCA AATATTGAAC CTCCTGAGAA TGTGGAGTGG 1440
AGTGGTGCTG AAGCCTCCAT GTTTAGAGTC CTCATTGGTA CTTACTACGA TAACTTTTGT 1500
GCCATTGCTA GGCTAATTGG GACCAAAACA TGTAGACAGG TGTATGAGTT TAGAGTCAAG 1560
GAGTCCAGTA TCATAGCACC TGTTCCCACT GAGGATGTAG ACACTCCTCC AAGAAAGAAG 1620
AAAAGGAAAC ATCGGTTGTG GGCTGCACAC TGCAGAAAGA TACAACTGAA AAAGGACGGC 1680
TCCTCTAACC ATGTTTACAA CTATCAACCC TGTGACCATC CACGGCAGCC TTGTGACAGT 1740
TCGTGCCCTT GTGTGATAGC ACAAAATTTT TGTGAAAAGT TTTGTCAATG TAGTTCAGAG 1800
TGTCAAAACC GCTTTCCTGG ATGTCGGTGC AAAGCACAAT GCAACACCAA ACAGTGTCCA 1860
TGCTACCTGG CTGTCCGAGA GTGTGACCCT GACCTCTGTC TCACGTGTGG AGCTGCTGAC 1920
CATTGGGACA GTAAAAATGT ATCCTGTAAG AACTGTAGCA TTCAGCGGGG CTCTAAAAAG 1980
CACTTACTGC TGGCACCGTC TGATGTGGCA GGCTGGGGCA TCTTTATCAA AGATCCTGTA 2040
CAGAAAAATG AATTCATCTC AGAATACTGT GGGGAGATTA TTTCTCAGGA TGAAGCAGAC 2100
AGAAGAGGAA AAGTGTATGA CAAATACATG TGCAGCTTTC TGTTCAACTT GAACAATGAT 2160
TTTGTGGTGG ATGCAACCCG AAAGGGCAAC AAAATTCGTT TTGCTAATCA TTCAGTAAAT 2220
CCAAACTGCT ATGCAAAAGT TATGATGGTT AATGGTGACC ACAGGATAGG CATCTTTGCT 2280
AAGAGGGCTA TCCAGACTGG TGAAGAGTTG TTTTTTGATT ACAGATACAG CCAGGCTGAT 2340
GCCCTGAAGT ATGTGGGCAT CGAACGAGAA ATGGAAATCC CTTGACATCT ACTACCTCTT 2400
CCCCTTCTCT CTGAAACAGC TGCCTTAGCT TCAGGAACCT TGAGTACTGT GGGCAATTTA 2460
GAAAACGGAA ATGCAGTTTG AAATTCTGAA TTTGCAAAGT ACTGTAACAG TAATTTATAG 2520
TAATGTTTTA AAATCAACTT TTTATTGCCT TCTCACCAGC TGCAAAGTGT TTTGTACCAG 2580
TGAGTTTTTG CAATAATGCA GTATGGTACA TTTTTCAAAT TTGAATAAAG AATACTTGAA 2640
CTTGTTGTTG AATCACTTGT CCTAGAACAT CACCGACTGA TTCTAGAAAG ACTATATCTA 2700
GTGGGAAAAC ACAACTTTGC TTTGTTTTTC CAGCTTGCTA TGAATATTTA ATAACCAATA 2760
AACATACTGG CATAGTGTTT GCCTAAA
2788Nucleotide Fasta Sequence
>ENSMUSP00000080419.6|SET1|Mus musculus
GCGTTTGGCGCTCGGTCCGGTCGCGTCCGACACCCAGTGGGACATCGAAGGCAGTGGAGTCCCGGCGGCGGCGGTGGCGGTGGCGGCGGGTTGGGGGCGACGCGCGGGAGAGGCGCGGGCTGGCGCGCGGGACGAAGAATAATCATGGGCCAGACTGGGAAGAAATCTGAGAAGGGACCGGTTTGTTGGCGGAAGCGTGTAAAATCAGAGTACATGAGACTGAGACAGCTCAAGAGGTTCAGAAGAGCTGATGAAGTAAAGACTATGTTTAGTTCCAATCGTCAGAAAATTTTGGAAAGAACTGAAACCTTAAACCAAGAGTGGAAGCAGCGGAGGATACAGCCTGTGCACATCATGACTTCTGTGAGCTCATTGCGCGGGACTAGGGAGTGTTCAGTCACCAGTGACTTGGATTTTCCAGCACAAGTCATCCCGTTAAAGACCCTGAATGCAGTCGCCTCGGTGCCTATAATGTACTCTTGGTCGCCCTTACAACAGAATTTTATGGTGGAAGACGAAACTGTTTTACATAACATTCCTTATATGGGGGATGAAGTTCTGGATCAGGATGGCACTTTCATTGAAGAACTAATAAAAAATTATGATGGAAAAGTGCATGGTGACAGAGAATGTGGATTTATAAATGATGAAATTTTTGTGGAGTTGGTAAATGCTCTTGGTCAATATAATGATGATGATGATGACGATGATGGAGATGATCCAGATGAAAGAGAAGAAAAACAGAAAGATCTAGAGGATAATCGAGATGATAAAGAAACTTGCCCACCTCGGAAATTTCCTGCTGATAAAATATTTGAAGCCATTTCCTCAATGTTTCCAGATAAGGGCACCGCAGAAGAACTGAAAGAAAAATATAAAGAACTCACGGAGCAGCAGCTCCCAGGTGCTCTGCCTCCTGAATGTACTCCAAACATCGATGGACCAAATGCCAAATCTGTTCAGAGGGAGCAAAGCTTGCATTCATTTCATACGCTCTTCTGTCGACGATGTTTTAAGTATGACTGCTTCCTACATCCCTTCCATGCAACACCCAACACATATAAGAGGAAGAACACAGAAACAGCTTTGGACAACAAGCCTTGTGGACCACAGTGTTACCAGCATCTGGAGGGAGCTAAGGAGTTTGCTGCTGCTCTTACTGCTGAGCGTATAAAGACACCACCTAAACGCCCAGGGGGCCGCAGAAGAGGAAGACTTCCGAATAACAGTAGCAGACCCAGCACCCCCACCATCAGTGTGCTGGAGTCAAAGGATACAGACAGTGACAGAGAAGCAGGGACTGAAACTGGGGGAGAGAACAATGATAAAGAAGAAGAAGAGAAAAAAGATGAGACGTCCAGCTCCTCTGAAGCAAATTCTCGGTGTCAAACACCAATAAAGATGAAGCCAAATATTGAACCTCCTGAGAATGTGGAGTGGAGTGGTGCTGAAGCCTCCATGTTTAGAGTCCTCATTGGTACTTACTACGATAACTTTTGTGCCATTGCTAGGCTAATTGGGACCAAAACATGTAGACAGGTGTATGAGTTTAGAGTCAAGGAGTCCAGTATCATAGCACCTGTTCCCACTGAGGATGTAGACACTCCTCCAAGAAAGAAGAAAAGGAAACATCGGTTGTGGGCTGCACACTGCAGAAAGATACAACTGAAAAAGGACGGCTCCTCTAACCATGTTTACAACTATCAACCCTGTGACCATCCACGGCAGCCTTGTGACAGTTCGTGCCCTTGTGTGATAGCACAAAATTTTTGTGAAAAGTTTTGTCAATGTAGTTCAGAGTGTCAAAACCGCTTTCCTGGATGTCGGTGCAAAGCACAATGCAACACCAAACAGTGTCCATGCTACCTGGCTGTCCGAGAGTGTGACCCTGACCTCTGTCTCACGTGTGGAGCTGCTGACCATTGGGACAGTAAAAATGTATCCTGTAAGAACTGTAGCATTCAGCGGGGCTCTAAAAAGCACTTACTGCTGGCACCGTCTGATGTGGCAGGCTGGGGCATCTTTATCAAAGATCCTGTACAGAAAAATGAATTCATCTCAGAATACTGTGGGGAGATTATTTCTCAGGATGAAGCAGACAGAAGAGGAAAAGTGTATGACAAATACATGTGCAGCTTTCTGTTCAACTTGAACAATGATTTTGTGGTGGATGCAACCCGAAAGGGCAACAAAATTCGTTTTGCTAATCATTCAGTAAATCCAAACTGCTATGCAAAAGTTATGATGGTTAATGGTGACCACAGGATAGGCATCTTTGCTAAGAGGGCTATCCAGACTGGTGAAGAGTTGTTTTTTGATTACAGATACAGCCAGGCTGATGCCCTGAAGTATGTGGGCATCGAACGAGAAATGGAAATCCCTTGACATCTACTACCTCTTCCCCTTCTCTCTGAAACAGCTGCCTTAGCTTCAGGAACCTTGAGTACTGTGGGCAATTTAGAAAACGGAAATGCAGTTTGAAATTCTGAATTTGCAAAGTACTGTAACAGTAATTTATAGTAATGTTTTAAAATCAACTTTTTATTGCCTTCTCACCAGCTGCAAAGTGTTTTGTACCAGTGAGTTTTTGCAATAATGCAGTATGGTACATTTTTCAAATTTGAATAAAGAATACTTGAACTTGTTGTTGAATCACTTGTCCTAGAACATCACCGACTGATTCTAGAAAGACTATATCTAGTGGGAAAACACAACTTTGCTTTGTTTTTCCAGCTTGCTATGAATATTTAATAACCAATAAACATACTGGCATAGTGTTTGCCTAAA
|
| Sequence Source |
Ensembl |
| Keyword |
KW-0002--3D-structure
KW-0025--Alternative splicing
KW-0090--Biological rhythms
KW-0156--Chromatin regulator
KW-0158--Chromosome
KW-0181--Complete proteome
KW-0325--Glycoprotein
KW-0489--Methyltransferase
KW-0539--Nucleus
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0678--Repressor
KW-0949--S-adenosyl-L-methionine
KW-0804--Transcription
KW-0805--Transcription regulation
KW-0808--Transferase
KW-0832--Ubl conjugation
--
|
| Interpro |
IPR026489--CXC_dom
IPR021654--EZH1/EZH2
IPR001005--SANT/Myb
IPR001214--SET_dom
IPR033467--Tesmin/TSO1-like_CXC
|
| PROSITE |
PS51633--CXC
PS50280--SET
|
| Pfam |
PF11616--EZH2_WD-Binding
PF00856--SET
|
| Gene Ontology |
GO:0005737--C:cytoplasm
GO:0035098--C:ESC/E(Z) complex
GO:0000790--C:nuclear chromatin
GO:0005654--C:nucleoplasm
GO:0005634--C:nucleus
GO:0045120--C:pronucleus
GO:0003682--F:chromatin binding
GO:0031490--F:chromatin DNA binding
GO:0001047--F:core promoter binding
GO:0042054--F:histone methyltransferase activity
GO:0018024--F:histone-lysine N-methyltransferase activity
GO:0070878--F:primary miRNA binding
GO:1990841--F:promoter-specific chromatin binding
GO:0016279--F:protein-lysine N-methyltransferase activity
GO:0043021--F:ribonucleoprotein complex binding
GO:0003723--F:RNA binding
GO:0000979--F:RNA polymerase II core promoter sequence-specific DNA binding
GO:0043565--F:sequence-specific DNA binding
GO:0014898--P:cardiac muscle hypertrophy in response to stress
GO:0070301--P:cellular response to hydrogen peroxide
GO:0035984--P:cellular response to trichostatin A
GO:0021695--P:cerebellar cortex development
GO:0006306--P:DNA methylation
GO:0070314--P:G1 to G0 transition
GO:0036333--P:hepatocyte homeostasis
GO:0021766--P:hippocampus development
GO:0070734--P:histone H3-K27 methylation
GO:0098532--P:histone H3-K27 trimethylation
GO:0016571--P:histone methylation
GO:0097421--P:liver regeneration
GO:0045605--P:negative regulation of epidermal cell differentiation
GO:2000134--P:negative regulation of G1/S transition of mitotic cell cycle
GO:0045814--P:negative regulation of gene expression, epigenetic
GO:0048387--P:negative regulation of retinoic acid receptor signaling pathway
GO:0043433--P:negative regulation of sequence-specific DNA binding transcription factor activity
GO:0051154--P:negative regulation of striated muscle cell differentiation
GO:0034244--P:negative regulation of transcription elongation from RNA polymerase II promoter
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0045892--P:negative regulation of transcription, DNA-templated
GO:1900006--P:positive regulation of dendrite development
GO:0010718--P:positive regulation of epithelial to mesenchymal transition
GO:0043547--P:positive regulation of GTPase activity
GO:0043406--P:positive regulation of MAP kinase activity
GO:0071902--P:positive regulation of protein serine/threonine kinase activity
GO:0071168--P:protein localization to chromatin
GO:0042127--P:regulation of cell proliferation
GO:0042752--P:regulation of circadian rhythm
GO:0010468--P:regulation of gene expression
GO:0014013--P:regulation of gliogenesis
GO:0050767--P:regulation of neurogenesis
GO:0001932--P:regulation of protein phosphorylation
GO:0006357--P:regulation of transcription from RNA polymerase II promoter
GO:0032355--P:response to estradiol
GO:1904772--P:response to tetrachloromethane
GO:0048511--P:rhythmic process
GO:0014834--P:skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration
GO:0006351--P:transcription, DNA-templated
|
| Orthology |
|
| Created Date |
25-Jun-2016 |
