Drosophila melanogaster      Me_Reader      PHD

※ PHD family introduction

    PHD: Distinct from the Royal family is the PHD finger, a well-characterized reader of H3K4me3. It contains a C4HC3 motif that coordinates two zinc ions in a cross-brace manner. Such an arrangement produces a globular domain with a small β-sheet and an α-helix. PHD fingers make extensive contacts with H3K4me3, imparting a high degree of specificity. (1)

Reference
1. Musselman CA, Lalonde ME, Cote J, Kutateladze TG.Perceiving the epigenetic landscape through histone readers. Nat Struct Mol Biol.2012;19(12):1218-27. PMID: 23211769.



There are 22 genes.  Reviewed (1 or Unreviewed (21

No.StatusWERAM IDGene/Alias Name
1
WERAM-Drm-0042
KDM5; lid; CG9088
2
WERAM-Drm-0007
Pcl
3
WERAM-Drm-0021
Chd3
4
WERAM-Drm-0027
bip2
5
WERAM-Drm-0033
CG3815
6
WERAM-Drm-0035
CG17440
7
WERAM-Drm-0036
Cfp1
8
WERAM-Drm-0038
Ing3
9
WERAM-Drm-0039
CG3347
10
WERAM-Drm-0041
CG15439
11
WERAM-Drm-0046
CG9293
12
WERAM-Drm-0048
d4
13
WERAM-Drm-0051
tou
14
WERAM-Drm-0055
rno
15
WERAM-Drm-0057
upSET
16
WERAM-Drm-0059
CG2926
17
WERAM-Drm-0066
CG7379
18
WERAM-Drm-0072
Mes-4
19
WERAM-Drm-0086
pps
20
WERAM-Drm-0088
e(y)3
21
WERAM-Drm-0093
Mi-2
22
WERAM-Drm-0094
Lpt