Oryzias latipes      Me_Reader      Chromodomain

※ Chromodomain family introduction

    Chromodomain: The chromodomain is the smallest member, consisting of four curved β-strands and an α-helix. The chromodomains of HP1 and Polycomb were found to recognize histone H3 trimethylated at K9 (H3K9me3) and H3K27me3, respectively, and these proteins were the first examples of readers specific for methyllysine. Chromodomains generally prefer trimethylated lysine, though some have been shown to bind dimethylated species. The aromatic cage of the chromodomain of mouse and fly HP1 contains an aspartate or glutamate residue, accounting for its ability to interact well with H3K9me3 and dimethylated H3K9 (H3K9me2). (1)

Reference
1. Musselman CA, Lalonde ME, Cote J, Kutateladze TG.Perceiving the epigenetic landscape through histone readers. Nat Struct Mol Biol.2012;19(12):1218-27. PMID: 23211769.



There are 11 genes.  Reviewed (0 or Unreviewed (11

No.StatusWERAM IDGene/Alias Name
1
WERAM-Orla-0010
cbx2
2
WERAM-Orla-0018
cbx8b
3
WERAM-Orla-0019
CBX4
4
WERAM-Orla-0076
cbx3b
5
WERAM-Orla-0077
cdyl
6
WERAM-Orla-0091
cbx4
7
WERAM-Orla-0092
cbx8a
8
WERAM-Orla-0098
CDYL2
9
WERAM-Orla-0109
nptxrb
10
WERAM-Orla-0130
cbx1b
11
WERAM-Orla-0161
cbx2