Medicago truncatula      HDAC      Class-I

※ Class-I family introduction

    Class-I: Class I HDACs share homology with the yeast Rpd3. This class includes HDACs 1, 2, 3, and 8, and its members are expressed ubiquitously in humans. Members 1, 2, and 3 are found in multi-protein repressor complexes in the nucleus, where they regulate gene expression. HDAC8 is found in both the nucleus and cytoplasm, and while it has not been found in any multi-protein complexes, it has been described to be involved in transcriptional repression. (1)

Reference
1. Koeneke, E., Witt, O., & Oehme, I.HDAC Family Members Intertwined in the Regulation of Autophagy: A Druggable Vulnerability in Aggressive Tumor Entities. Cells.2015;4(2):135-168. PMID: 25915736.



There are 10 genes.  Reviewed (0 or Unreviewed (10

No.StatusWERAM IDGene/Alias Name
1
WERAM-Met-0014
MTR_1g016440
2
WERAM-Met-0052
MTR_2g087270 MtrDRAFT_AC151522g23v2
3
WERAM-Met-0067
MTR_3g077120
4
WERAM-Met-0068
MTR_3g077160
5
WERAM-Met-0084
MTR_3g118535
6
WERAM-Met-0097
MTR_4g055080
7
WERAM-Met-0112
MTR_4g109500
8
WERAM-Met-0113
MTR_4g111985
9
WERAM-Met-0119
MTR_5g004640
10
WERAM-Met-0183
MTR_8g093800