WERAM Information

Tag Content
WERAM ID WERAM-Cae-0042
Ensembl Protein ID F57C7.1a.2
Uniprot Accession Q20947; Q20947_CAEEL
Genbank Protein ID NP_509770.2
Protein Name BET (Two bromodomains) family protein
Genbank Nucleotide ID NM_077369.4
Gene Name BET2;CELE_F57C7.1
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
WBGene00010199 F57C7.1a.2 F57C7.1a.2
WBGene00010199 F57C7.1a.1 F57C7.1a.1
WBGene00010199 F57C7.1b.1 F57C7.1b.1
WBGene00010199 F57C7.1b.2 F57C7.1b.2
Details
Type Family Domain Substrates AA References (PMIDs)
Ac_Reader Bromodomain Bromodomain K 25254151
Status Reviewed
Classification
Type Family E-value Score Start End
Ac_Reader Bromodomain 2.10e-44 150 300 640
Organism Caenorhabditis elegans
NCBI Taxa ID 6239
Functional Description
(View)
Domain Profile
  Ac_Reader Bromodomain
   BROMO.txt   2 ehevsepFrepvdpq.leipdYydiikePmdLstikerleegnYsspeefvkDvrlifnNakaynenkssvq 72 
                 +h++s+pF+ pvd+  leip+Y++i+++PmdL ti++rl++ +Y+ +e+ +kD++++f N++ +n+++ +v+
  F57C7.1a.2 300 KHKHSWPFQLPVDAIkLEIPEYHNIVNTPMDLRTIEKRLRNLYYWCAEDAIKDINQVFINCYSFNPPEYDVY 371
                 699****************************************************************99987 PP
   BROMO.txt   4 evsepFrepvdpq.leipdYydiikePmdLstikerleegnYsspeefvkDvrlifnNakaynenks 69 
                  ++++F  pvdp  l+i dY ++i +PmdL+tik++l+ ++Y +peefv+D++l+++N+ +yn+++s
  F57C7.1a.2 574 GFAQVFYLPVDPIkLKIYDYLEVITNPMDLQTIKKKLDFKQYAEPEEFVHDINLMVDNCCKYNPKGS 640
                 57899********9*************************************************9987 PP
Protein Sequence
(Fasta)		MSDYSAKPSG SLARIGDYDL SSDDSDQNDE DETLIASKTI QTGAVQVNDI AVAEASPAET 60
DAKSSASPVS GPEPPTSAVV ENRDLDEFKK ESGSNDDKQE EINEDKDSNE ETVFQQTESG 120
SADVVDKTDV KQKDSDSSAD DDHSHSKSGS VHSPQKPQGS TTPCSVQSPA SPVGDEQAVK 180
MEEVEEPIVA SEEVPDKKPE SVKESTDSES SGSEHGFEKM DTAEKVEDEC NDDEVAASNG 240
TEEPEPGDKA ADTVNPWETP RQEPVDGVVQ PRTEPPAGKP TRHTNCLDFV LFTVVKDALK 300
HKHSWPFQLP VDAIKLEIPE YHNIVNTPMD LRTIEKRLRN LYYWCAEDAI KDINQVFINC 360
YSFNPPEYDV YKMAKTLEKQ VLSQLTQLPR SEKPADLADH HRRGMFSAST PSGKTKGPKQ 420
RGRKSTRGRK KTSLPRGAST FKDESVDDNN DDESSKVDSI NFDDDDDTAT EKDAESRAES 480
VQPEVVNEEP KPSTSQPPSK KRKAENGEPA VAVKIATPAT PVAAHPQEET PRRKNPNTLI 540
EWKHLVPRWQ GKIPEWQKFC SKLLNEIHSV KNKGFAQVFY LPVDPIKLKI YDYLEVITNP 600
MDLQTIKKKL DFKQYAEPEE FVHDINLMVD NCCKYNPKGS PAHSNALELR SFFEQRWKLF 660
PRPGVDPIIA DSYINQNLVV NTDLIEDERI NSYLSAVKAE EKKCAEKLEQ LRSMSEGLYT 720
IAMQRREAKL AGNTAPALAQ NQLSQLEGLG ISIKSTPMMI PELISPALSV RSSSRAPVPK 780
IIDDIGPSPI KARKISKPRA SMASNVSVPY TPTGNPRGRK PKKSGRPKKN IYSPATVSER 840
ISQQPPFEVT PYVSIYGRKV VGTNDKIELS ERMASIPQMY ITPILRIIQI GHHNTGKTIT 900
SLRSLCEEEI DFNDVSDDLV IELLDYLEMI QKDKAKAEQV RQELEVKAKF YGFEAYDNKL 960
GTIPKTRNMP PPLQHRMRSD SPSPSASRTG NQSSDSDSAS DDSSDDEPSR SNSNVAGPRR 1020
ALELSGNSSS ASTPAGPSKA QPAVVRPSSK SVASKPAYTK RTLSESSSSS DSNGSSSDSS 1080
DSDSEPKPQA KKPEPPQKKV AKKPAPQQKK KAPLSILDEL LPDTPEKKPV MASVPTTSGS 1140
ARQLPPDSYQ KPSQISEAEL KAQKEQEHNA ALQRREEARR LRALEDQQQV LNQHEVMHEF 1200
ESQYGDFSY 1209
Nucleotide Sequence
(Fasta)		TTTTTATGGG ATGACTGAAT ATTTCAAAAC ATGGAAAATT GTTTATTCTA AAGATTAATG 60
TAGGGATATC TTGCTGATTT CGTTTAATTC TTTCTCACGT TTTTTGTTTG TTAATTGTAA 120
GGAACAAATC AAACTAATCG AGTTTCATTT TCAGATGTCA GACTACAGTG CAAAGCCGTC 180
GGGCAGTTTG GCGCGCATTG GGGACTACGA CCTTAGCTCA GATGATTCCG ATCAGAATGA 240
CGAGGACGAA ACTCTGATAG CTTCAAAAAC AATACAAACG GGCGCTGTTC AGGTGAACGA 300
TATTGCTGTT GCCGAGGCAT CTCCAGCAGA AACTGATGCA AAGTCGAGTG CAAGTCCGGT 360
TTCGGGTCCG GAGCCACCAA CATCAGCAGT CGTTGAAAAC AGAGATCTTG ATGAATTTAA 420
AAAAGAATCG GGTAGCAACG ATGACAAGCA AGAGGAAATT AATGAGGACA AGGATTCCAA 480
TGAAGAAACA GTTTTCCAAC AAACAGAAAG TGGATCTGCA GACGTTGTTG ATAAAACAGA 540
CGTGAAGCAA AAAGACTCTG ATTCCTCTGC AGATGATGAT CACTCTCATA GCAAAAGCGG 600
CAGTGTTCAC AGTCCACAGA AACCACAAGG TTCCACCACG CCGTGCAGTG TTCAGAGCCC 660
AGCTAGTCCA GTAGGCGATG AGCAAGCTGT TAAGATGGAA GAGGTCGAAG AGCCAATTGT 720
CGCATCAGAA GAAGTTCCTG ACAAGAAACC AGAATCCGTC AAAGAATCCA CAGATTCAGA 780
GTCAAGTGGA AGTGAGCATG GTTTTGAGAA AATGGATACT GCTGAAAAGG TAGAAGATGA 840
ATGTAACGAC GATGAAGTGG CAGCTTCCAA TGGCACAGAA GAACCGGAAC CAGGCGACAA 900
AGCTGCAGAT ACTGTGAATC CGTGGGAAAC GCCTAGACAG GAACCTGTCG ATGGTGTCGT 960
CCAACCACGC ACTGAACCAC CTGCGGGTAA ACCAACTCGT CACACCAACT GCCTTGATTT 1020
TGTGCTTTTC ACCGTTGTGA AAGATGCTTT GAAGCACAAG CACTCGTGGC CTTTTCAGTT 1080
GCCGGTTGAT GCTATCAAAT TGGAAATTCC TGAATATCAC AATATTGTCA ACACTCCCAT 1140
GGACCTGCGA ACCATCGAGA AACGGCTCCG TAATTTATAT TATTGGTGTG CTGAGGATGC 1200
AATAAAAGAC ATCAACCAAG TGTTCATCAA TTGTTACTCG TTCAATCCAC CAGAATATGA 1260
CGTTTACAAA ATGGCCAAAA CTCTGGAGAA GCAAGTGTTA AGCCAGTTAA CGCAGCTCCC 1320
GCGATCTGAA AAACCGGCTG ATCTCGCTGA TCATCATCGT CGGGGAATGT TTTCTGCATC 1380
GACACCTAGT GGCAAGACAA AGGGACCAAA GCAGCGTGGA AGAAAAAGCA CCCGTGGCCG 1440
GAAGAAGACC TCACTTCCTC GTGGAGCCTC TACTTTCAAG GATGAGTCCG TGGACGATAA 1500
TAATGACGAT GAGTCATCCA AAGTGGATTC TATCAATTTT GACGACGACG ATGATACTGC 1560
CACTGAAAAA GATGCCGAGA GTCGTGCAGA ATCTGTTCAA CCAGAGGTCG TTAATGAAGA 1620
GCCAAAGCCT TCCACTTCTC AACCACCATC AAAAAAGCGC AAAGCTGAAA ATGGTGAACC 1680
AGCAGTTGCT GTGAAAATTG CTACTCCAGC GACCCCAGTG GCTGCACATC CTCAAGAAGA 1740
AACACCTCGA CGCAAAAATC CGAACACTTT GATTGAATGG AAACATCTTG TTCCTCGCTG 1800
GCAAGGTAAA ATTCCTGAAT GGCAAAAGTT TTGCTCAAAG CTTCTAAACG AAATTCACAG 1860
TGTTAAAAAC AAAGGTTTTG CTCAAGTTTT CTACTTGCCT GTTGACCCCA TCAAGCTGAA 1920
AATCTACGAT TACTTGGAAG TCATCACTAA CCCAATGGAC TTGCAAACAA TTAAAAAGAA 1980
ACTTGATTTT AAGCAATATG CTGAGCCAGA AGAATTTGTT CATGACATCA ACCTAATGGT 2040
TGACAATTGT TGCAAATACA ACCCAAAAGG CTCACCAGCT CATTCCAACG CTTTGGAACT 2100
CAGGTCCTTT TTTGAACAAC GATGGAAGTT GTTTCCTCGT CCAGGTGTCG ATCCAATCAT 2160
TGCCGACTCG TACATCAATC AAAATCTAGT CGTAAACACT GATCTTATTG AGGACGAGCG 2220
TATCAACAGT TATTTGAGTG CCGTCAAAGC TGAGGAGAAA AAGTGTGCTG AAAAGTTGGA 2280
ACAACTTCGT AGCATGAGTG AAGGTCTTTA CACCATTGCC ATGCAGCGTC GTGAAGCCAA 2340
ATTAGCTGGA AATACAGCTC CGGCTCTAGC TCAAAATCAG TTATCACAAT TGGAAGGTCT 2400
TGGAATCAGC ATCAAGTCGA CACCAATGAT GATTCCTGAG CTGATTTCAC CAGCTCTGTC 2460
TGTGCGATCT TCTAGTCGAG CTCCTGTTCC CAAGATCATT GATGACATCG GACCATCGCC 2520
AATCAAAGCA AGAAAAATAT CGAAACCTCG TGCTTCTATG GCTTCGAACG TATCTGTGCC 2580
CTACACTCCT ACAGGTAACC CTCGCGGAAG GAAACCAAAG AAGTCGGGTC GTCCAAAGAA 2640
GAATATTTAC TCGCCGGCGA CTGTTTCAGA AAGAATATCA CAACAACCGC CGTTTGAGGT 2700
CACTCCTTAT GTGTCTATTT ACGGAAGAAA GGTAGTCGGT ACTAACGACA AGATAGAGCT 2760
CTCTGAGCGA ATGGCTTCTA TTCCACAAAT GTACATTACT CCGATCTTGC GCATTATTCA 2820
AATTGGACAC CACAACACTG GAAAAACCAT TACGTCCCTT CGTTCCCTTT GTGAGGAGGA 2880
AATTGACTTT AACGACGTTT CTGACGACTT AGTCATCGAG CTGTTGGATT ATCTTGAGAT 2940
GATTCAAAAG GACAAAGCGA AGGCTGAGCA AGTTAGACAG GAGCTTGAAG TAAAAGCAAA 3000
GTTCTATGGT TTTGAAGCAT ACGACAATAA ACTTGGAACA ATCCCCAAAA CTCGGAACAT 3060
GCCGCCTCCA TTACAACATC GTATGCGCTC CGACTCGCCA TCTCCATCGG CTTCGCGTAC 3120
CGGCAACCAA TCATCTGATT CGGATTCTGC ATCGGATGAT TCATCGGATG ATGAGCCAAG 3180
CCGTAGCAAC AGTAATGTAG CTGGTCCTCG CCGTGCCCTC GAGTTGAGTG GAAACTCATC 3240
CAGTGCGTCT ACTCCAGCAG GGCCCAGCAA AGCTCAGCCT GCAGTTGTCC GTCCGTCGTC 3300
AAAATCGGTG GCTTCAAAGC CGGCATACAC AAAGCGGACG TTGTCAGAAA GCTCGAGTTC 3360
GTCGGACAGC AACGGTTCAT CGTCGGACTC GTCTGATTCG GATTCTGAGC CAAAACCACA 3420
GGCCAAGAAA CCTGAGCCGC CACAAAAGAA AGTTGCAAAA AAACCAGCTC CACAGCAAAA 3480
AAAGAAAGCC CCACTTTCAA TTTTGGATGA ACTTCTTCCG GACACACCCG AGAAAAAACC 3540
AGTGATGGCC TCTGTCCCAA CTACTAGTGG ATCTGCACGG CAACTTCCAC CAGACTCATA 3600
TCAAAAGCCA TCTCAAATTT CGGAAGCCGA GTTGAAAGCT CAAAAGGAAC AGGAGCACAA 3660
TGCTGCTTTG CAACGAAGGG AAGAGGCTCG TCGTCTCCGA GCTCTTGAAG ACCAACAGCA 3720
AGTCTTGAAT CAACACGAAG TTATGCATGA ATTCGAAAGT CAGTACGGCG ATTTTTCATA 3780
TTAATGCTCA ATTGGCCAAC CATTTTCATT AAATGTATTG TTAAATAACA ATGATATCTC 3840
TAGCAACCTC ACACCGATCC CCAATCCCCT GATCTTATGC CAAATTTAAT TATTAATTGT 3900
TTGTTTAACT TATTTGTTTG AATTCCAAGG GTCCCACATT AGCAGTTTGT CATGGCTGCA 3960
GTTACAGTAA CGTTTCTGTA AAACCACCTT CCATTCACTT TCATCCCCGT CAATCACCAC 4020
AATCATCATT TCAAAGCCTT CTTTACTTGA TCAACAACAC TGAATCTCGT TTGCAGTAGA 4080
GAGTATTAAT AATTATTAAA TAGGTTTGTG TTTAAGAATT AAGTAATTGT TTGTTTACTT 4140
TTTGATTGAA TTAGAATTAC CTCGTCCCAT CCCAAATTGA TCCATATACT GGATTTTTTA 4200
TCTCAAATTT TACCTCAAAT TACTCAATTG GCATGAAACC AATTATCACA TTTTTTTACT 4260
TTCCAAATAA ATTATGAAAC TTTAAA 4287
Sequence Source Ensembl
Keyword

KW-0103--Bromodomain
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1267--Proteomics identification
KW-1185--Reference proteome
--
Interpro

IPR001487--Bromodomain
IPR018359--Bromodomain_CS
PROSITE

PS00633--BROMODOMAIN_1
PS50014--BROMODOMAIN_2
Pfam

PF00439--Bromodomain
Gene Ontology
Orthology
WERAM ID Ensembl Protein ID Species Identity E-value Score
WERAM-Drm-0012 FBpp0071074 Drosophila melanogaster 51 2e-37 155
WERAM-Tar-0198 ENSTRUP00000040915.1 Takifugu rubripes 47 2e-32 139
WERAM-Ten-0035 ENSTNIP00000006103.1 Tetraodon nigroviridis 46 1e-31 136
WERAM-Xim-0164 ENSXMAP00000013480.1 Xiphophorus maculatus 46 2e-31 136
WERAM-Orn-0021 ENSONIP00000002329.1 Oreochromis niloticus 46 2e-31 135
WERAM-Ocp-0044 ENSOPRP00000003823.1 Ochotona princeps 40 3e-31 135
WERAM-Pof-0078 ENSPFOP00000007050.2 Poecilia formosa 49 3e-31 135
WERAM-Orla-0063 ENSORLP00000008149.1 Oryzias latipes 51 3e-31 135
WERAM-Xet-0088 ENSXETP00000028569.3 Xenopus tropicalis 46 4e-31 135
WERAM-Lac-0047 ENSLACP00000006835.1 Latimeria chalumnae 44 4e-31 134
WERAM-Paa-0190 ENSPANP00000010376.1 Papio anubis 39 5e-31 134
WERAM-Orc-0130 ENSOCUP00000011195.2 Oryctolagus cuniculus 39 6e-31 134
WERAM-Hos-0138 ENSP00000263377.1 Homo sapiens 37 6e-31 134
WERAM-Poa-0084 ENSPPYP00000010837.2 Pongo abelii 37 6e-31 134
WERAM-Nol-0052 ENSNLEP00000006353.1 Nomascus leucogenys 37 6e-31 134
WERAM-Loa-0079 ENSLAFP00000005884.3 Loxodonta africana 50 7e-31 134
WERAM-Mim-0129 ENSMICP00000013010.1 Microcebus murinus 39 7e-31 134
WERAM-Gog-0122 ENSGGOP00000010164.2 Gorilla gorilla 39 7e-31 134
WERAM-Mam-0196 ENSMMUP00000028168.2 Macaca mulatta 39 7e-31 134
WERAM-Chs-0069 ENSCSAP00000002413.1 Chlorocebus sabaeus 39 7e-31 134
WERAM-Mum-0055 ENSMUSP00000113070.1 Mus musculus 37 7e-31 134
WERAM-Ran-0040 ENSRNOP00000008963.6 Rattus norvegicus 45 8e-31 134
WERAM-Cap-0011 ENSCPOP00000001274.2 Cavia porcellus 39 8e-31 134
WERAM-Otg-0016 ENSOGAP00000000748.2 Otolemur garnettii 47 9e-31 133
WERAM-Eqc-0187 ENSECAP00000019958.1 Equus caballus 50 9e-31 133
WERAM-Pat-0089 ENSPTRP00000018122.4 Pan troglodytes 37 1e-30 133
WERAM-Ova-0027 ENSOARP00000003891.1 Ovis aries 50 1e-30 133
WERAM-Bot-0030 ENSBTAP00000003242.5 Bos taurus 50 1e-30 133
WERAM-Tut-0179 ENSTTRP00000015157.1 Tursiops truncatus 50 1e-30 133
WERAM-Fec-0010 ENSFCAP00000000851.2 Felis catus 50 1e-30 133
WERAM-Ptv-0180 ENSPVAP00000015952.1 Pteropus vampyrus 46 1e-30 133
WERAM-Caf-0165 ENSCAFP00000023676.4 Canis familiaris 50 1e-30 133
WERAM-Aim-0034 ENSAMEP00000002443.1 Ailuropoda melanoleuca 50 1e-30 133
WERAM-Anp-0078 ENSAPLP00000009547.1 Anas platyrhynchos 46 1e-30 133
WERAM-Sus-0153 ENSSSCP00000019596.1 Sus scrofa 50 1e-30 133
WERAM-Ora-0083 ENSOANP00000013848.2 Ornithorhynchus anatinus 50 1e-30 133
WERAM-Caj-0016 ENSCJAP00000003945.2 Callithrix jacchus 47 2e-30 132
WERAM-Mae-0088 ENSMEUP00000008845.1 Macropus eugenii 50 2e-30 132
WERAM-Dio-0017 ENSDORP00000002078.1 Dipodomys ordii 39 2e-30 132
WERAM-Myl-0052 ENSMLUP00000004424.2 Myotis lucifugus 50 2e-30 132
WERAM-Mup-0183 ENSMPUP00000015981.1 Mustela putorius furo 50 2e-30 132
WERAM-Dar-0210 ENSDARP00000129878.1 Danio rerio 48 2e-30 132
WERAM-Sah-0090 ENSSHAP00000010568.1 Sarcophilus harrisii 50 2e-30 132
WERAM-Mod-0130 ENSMODP00000018187.4 Monodelphis domestica 50 2e-30 132
WERAM-Anc-0179 ENSACAP00000017011.3 Anolis carolinensis 49 2e-30 132
WERAM-Gaga-0127 ENSGALP00000035122.2 Gallus gallus 46 2e-30 132
WERAM-Ect-0055 ENSETEP00000005894.1 Echinops telfairi 46 2e-30 132
WERAM-Meg-0092 ENSMGAP00000008728.2 Meleagris gallopavo 46 4e-30 131
WERAM-Leo-0065 ENSLOCP00000008328.1 Lepisosteus oculatus 45 6e-30 130
WERAM-Ict-0138 ENSSTOP00000014229.2 Ictidomys tridecemlineatus 49 6e-30 130
WERAM-Asm-0076 ENSAMXP00000007951.1 Astyanax mexicanus 47 2e-29 129
WERAM-Fia-0022 ENSFALP00000001679.1 Ficedula albicollis 48 3e-29 128
WERAM-Gam-0097 ENSGMOP00000009935.1 Gadus morhua 40 7e-29 127
WERAM-Dan-0036 ENSDNOP00000003814.2 Dasypus novemcinctus 49 1e-28 127
WERAM-Prc-0094 ENSPCAP00000008495.1 Procavia capensis 46 1e-28 126
WERAM-Gaa-0105 ENSGACP00000013356.1 Gasterosteus aculeatus 47 2e-28 125
WERAM-Pem-0020 ENSPMAP00000002717.1 Petromyzon marinus 45 1e-27 123
WERAM-Vip-0081 ENSVPAP00000007489.1 Vicugna pacos 45 3e-27 122
WERAM-Chh-0100 ENSCHOP00000011481.1 Choloepus hoffmanni 48 2e-25 116
WERAM-Tub-0130 ENSTBEP00000014498.1 Tupaia belangeri 43 6e-25 114
WERAM-Tas-0103 ENSTSYP00000010758.1 Tarsius syrichta 46 6e-25 114
WERAM-Soa-0112 ENSSARP00000010657.1 Sorex araneus 47 4e-24 111
WERAM-Pes-0007 ENSPSIP00000002650.1 Pelodiscus sinensis 41 1e-23 110
WERAM-Tag-0083 ENSTGUP00000005921.1 Taeniopygia guttata 43 4e-23 108
WERAM-Ere-0086 ENSEEUP00000008250.1 Erinaceus europaeus 48 7e-23 107
WERAM-Cis-0028 ENSCSAVP00000005883.1 Ciona savignyi 38 2e-22 106
WERAM-Scj-0016 EEB07414 Schizosaccharomyces japonicus 35 2e-22 105
WERAM-Mel-0021 EGG12926 Melampsora laricipopulina 43 2e-21 102
Created Date 25-Jun-2016