WERAM Information


Tag Content
WERAM ID WERAM-Hos-0038
Ensembl Protein ID ENSP00000371638.1
Uniprot Accession P51531; SMCA2_HUMAN; B1ALG3; B1ALG4; D3DRH4; D3DRH5
Genbank Protein ID NP_001276325.1; NP_001276326.1; NP_003061.3; NP_620614.2
Protein Name Probable global transcription activator SNF2L2
Genbank Nucleotide ID NM_001289396.1; NM_001289397.1; NM_003070.4; NM_139045.3
Gene Name SMARCA2;BAF190B;BRM;SNF2A;SNF2L2
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSG00000080503.20 ENST00000382203.5 ENSP00000371638.1
ENSG00000080503.20 ENST00000349721.7 ENSP00000265773.5
ENSG00000080503.20 ENST00000302401.8 ENSP00000305411.3
ENSG00000080503.20 ENST00000324954.10 ENSP00000324770.6
ENSG00000080503.20 ENST00000357248.7 ENSP00000349788.2
ENSG00000080503.20 ENST00000382183.6 ENSP00000371618.1
ENSG00000080503.20 ENST00000382185.6 ENSP00000371620.2
ENSG00000080503.20 ENST00000382186.6 ENSP00000371621.1
ENSG00000080503.20 ENST00000382194.6 ENSP00000371629.1
ENSG00000080503.20 ENST00000417599.6 ENSP00000387486.2
ENSG00000080503.20 ENST00000450198.6 ENSP00000392081.2
ENSG00000080503.20 ENST00000452193.5 ENSP00000401096.2
ENSG00000080503.20 ENST00000416751.2 ENSP00000412242.2
ENSG00000080503.20 ENST00000423555.6 ENSP00000413057.2
ENSG00000080503.20 ENST00000635133.1 ENSP00000489168.1
ENSG00000080503.20 ENST00000635530.1 ENSP00000489204.1
ENSG00000080503.20 ENST00000634435.1 ENSP00000489212.1
ENSG00000080503.20 ENST00000635388.1 ENSP00000489271.1
ENSG00000080503.20 ENST00000634781.1 ENSP00000489302.1
ENSG00000080503.20 ENST00000634338.1 ENSP00000489388.1
ENSG00000080503.20 ENST00000634931.1 ENSP00000489433.1
ENSG00000080503.20 ENST00000634688.1 ENSP00000489473.1
ENSG00000080503.20 ENST00000635392.1 ENSP00000489501.1
ENSG00000080503.20 ENST00000634706.1 ENSP00000489504.1
ENSG00000080503.20 ENST00000634772.1 ENSP00000489518.1
ENSG00000080503.20 ENST00000634343.1 ENSP00000489615.1
Details
Type Family Domain Substrates AA References (PMIDs)
Ac_Reader Bromodomain Bromodomain H3K9; H3K14; H4K5; H4K8; H4K12; H4K16 K 22464331
Status Reviewed
Classification
Type Family E-value Score Start End
Ac_Reader Bromodomain 5.10e-17 64 1421 1489
Organism Homo sapiens
NCBI Taxa ID 9606
Functional Description
(View)
Transcriptional coactivator cooperating with nuclear hormone receptors to potentiate transcriptional activation. Belongs to the neural progenitors-specific chromatin remodeling complex (npBAF complex) and the neuron-specific chromatin remodeling complex (nBAF complex). During neural development a switch from a stem/progenitor to a postmitotic chromatin remodeling mechanism occurs as neurons exit the cell cycle and become committed to their adult state. The transition from proliferating neural stem/progenitor cells to postmitotic neurons requires a switch in subunit composition of the npBAF and nBAF complexes. As neural progenitors exit mitosis and differentiate into neurons, npBAF complexes which contain ACTL6A/BAF53A and PHF10/BAF45A, are exchanged for homologous alternative ACTL6B/BAF53B and DPF1/BAF45B or DPF3/BAF45C subunits in neuron-specific complexes (nBAF). The npBAF complex is essential for the self-renewal/proliferative capacity of the multipotent neural stem cells. The nBAF complex along with CREST plays a role regulating the activity of genes essential for dendrite growth (By similarity).
Domain Profile
  Ac_Reader Bromodomain

          BROMO.txt    3 hevsepF.repvdpqleipdYydiikePmdLstikerleegnYsspeefvkDvrlifnNakaynenkssvq 72  
+++se+F + p+++ e+p+Yy++i++P+d+++iker+++++Y+s+ ++ kDv l+++Na+++n ++s+++
ENSP00000371638.1 1421 RQLSEVFiQLPSRK--ELPEYYELIRKPVDFKKIKERIRNHKYRSLGDLEKDVMLLCHNAQTFNLEGSQIY 1489
789****7777777..9***********************************************9999886 PP

Protein Sequence
(Fasta)
MSTPTDPGAM PHPGPSPGPG PSPGPILGPS PGPGPSPGSV HSMMGPSPGP PSVSHPMPTM 60
GSTDFPQEGM HQMHKPIDGI HDKGIVEDIH CGSMKGTGMR PPHPGMGPPQ SPMDQHSQGY 120
MSPHPSPLGA PEHVSSPMSG GGPTPPQMPP SQPGALIPGD PQAMSQPNRG PSPFSPVQLH 180
QLRAQILAYK MLARGQPLPE TLQLAVQGKR TLPGLQQQQQ QQQQQQQQQQ QQQQQQQQPQ 240
QQPPQPQTQQ QQQPALVNYN RPSGPGPELS GPSTPQKLPV PAPGGRPSPA PPAAAQPPAA 300
AVPGPSVPQP APGQPSPVLQ LQQKQSRISP IQKPQGLDPV EILQEREYRL QARIAHRIQE 360
LENLPGSLPP DLRTKATVEL KALRLLNFQR QLRQEVVACM RRDTTLETAL NSKAYKRSKR 420
QTLREARMTE KLEKQQKIEQ ERKRRQKHQE YLNSILQHAK DFKEYHRSVA GKIQKLSKAV 480
ATWHANTERE QKKETERIEK ERMRRLMAED EEGYRKLIDQ KKDRRLAYLL QQTDEYVANL 540
TNLVWEHKQA QAAKEKKKRR RRKKKAEENA EGGESALGPD GEPIDESSQM SDLPVKVTHT 600
ETGKVLFGPE APKASQLDAW LEMNPGYEVA PRSDSEESDS DYEEEDEEEE SSRQETEEKI 660
LLDPNSEEVS EKDAKQIIET AKQDVDDEYS MQYSARGSQS YYTVAHAISE RVEKQSALLI 720
NGTLKHYQLQ GLEWMVSLYN NNLNGILADE MGLGKTIQTI ALITYLMEHK RLNGPYLIIV 780
PLSTLSNWTY EFDKWAPSVV KISYKGTPAM RRSLVPQLRS GKFNVLLTTY EYIIKDKHIL 840
AKIRWKYMIV DEGHRMKNHH CKLTQVLNTH YVAPRRILLT GTPLQNKLPE LWALLNFLLP 900
TIFKSCSTFE QWFNAPFAMT GERVDLNEEE TILIIRRLHK VLRPFLLRRL KKEVESQLPE 960
KVEYVIKCDM SALQKILYRH MQAKGILLTD GSEKDKKGKG GAKTLMNTIM QLRKICNHPY 1020
MFQHIEESFA EHLGYSNGVI NGAELYRASG KFELLDRILP KLRATNHRVL LFCQMTSLMT 1080
IMEDYFAFRN FLYLRLDGTT KSEDRAALLK KFNEPGSQYF IFLLSTRAGG LGLNLQAADT 1140
VVIFDSDWNP HQDLQAQDRA HRIGQQNEVR VLRLCTVNSV EEKILAAAKY KLNVDQKVIQ 1200
AGMFDQKSSS HERRAFLQAI LEHEEENEEE DEVPDDETLN QMIARREEEF DLFMRMDMDR 1260
RREDARNPKR KPRLMEEDEL PSWIIKDDAE VERLTCEEEE EKIFGRGSRQ RRDVDYSDAL 1320
TEKQWLRAIE DGNLEEMEEE VRLKKRKRRR NVDKDPAKED VEKAKKRRGR PPAEKLSPNP 1380
PKLTKQMNAI IDTVINYKDR CNVEKVPSNS QLEIEGNSSG RQLSEVFIQL PSRKELPEYY 1440
ELIRKPVDFK KIKERIRNHK YRSLGDLEKD VMLLCHNAQT FNLEGSQIYE DSIVLQSVFK 1500
SARQKIAKEE ESEDESNEEE EEEDEEESES EAKSVKVKIK LNKKDDKGRD KGKGKKRPNR 1560
GKAKPVVSDF DSDEEQDERE QSEGSGTDDE
Nucleotide Sequence
(Fasta)
TCAGAAGAAA GCCCCGAGAT CACAGAGACC CGGCGAGATC ACAGAGACCC GGCCTGAAGG 60
AACGTGGAAA GACCAATGTA CCTGTTTTGA CCGGTTGCCT GGAGCAAGAA GTTCCAGTTG 120
GGGAGAATTT TCAGAAGATA AAGTCGGAGA TTGTGGAAAG ACTTGACTTG CAGCATTACT 180
CTACTGACTG GCAGAGACAG GAGAGGTAGA TGTCCACGCC CACAGACCCT GGTGCGATGC 240
CCCACCCAGG GCCTTCGCCG GGGCCTGGGC CTTCCCCTGG GCCAATTCTT GGGCCTAGTC 300
CAGGACCAGG ACCATCCCCA GGTTCCGTCC ACAGCATGAT GGGGCCAAGT CCTGGACCTC 360
CAAGTGTCTC CCATCCTATG CCGACGATGG GGTCCACAGA CTTCCCACAG GAAGGCATGC 420
ATCAAATGCA TAAGCCCATC GATGGTATAC ATGACAAGGG GATTGTAGAA GACATCCATT 480
GTGGATCCAT GAAGGGCACT GGTATGCGAC CACCTCACCC AGGCATGGGC CCTCCCCAGA 540
GTCCAATGGA TCAACACAGC CAAGGTTATA TGTCACCACA CCCATCTCCA TTAGGAGCCC 600
CAGAGCACGT CTCCAGCCCT ATGTCTGGAG GAGGCCCAAC TCCACCTCAG ATGCCACCAA 660
GCCAGCCGGG GGCCCTCATC CCAGGTGATC CGCAGGCCAT GAGCCAGCCC AACAGAGGTC 720
CCTCACCTTT CAGTCCTGTC CAGCTGCATC AGCTTCGAGC TCAGATTTTA GCTTATAAAA 780
TGCTGGCCCG AGGCCAGCCC CTCCCCGAAA CGCTGCAGCT TGCAGTCCAG GGGAAAAGGA 840
CGTTGCCTGG CTTGCAGCAA CAACAGCAGC AGCAACAGCA GCAGCAGCAG CAGCAGCAGC 900
AGCAGCAGCA GCAGCAACAG CAGCCGCAGC AGCAGCCGCC GCAACCACAG ACGCAGCAAC 960
AACAGCAGCC GGCCCTTGTT AACTACAACA GACCATCTGG CCCGGGGCCG GAGCTGAGCG 1020
GCCCGAGCAC CCCGCAGAAG CTGCCGGTGC CCGCGCCCGG CGGCCGGCCC TCGCCCGCGC 1080
CCCCCGCAGC CGCGCAGCCG CCCGCGGCCG CAGTGCCCGG GCCCTCAGTG CCGCAGCCGG 1140
CCCCGGGGCA GCCCTCGCCC GTCCTCCAGC TGCAGCAGAA GCAGAGCCGC ATCAGCCCCA 1200
TCCAGAAACC GCAAGGCCTG GACCCCGTGG AAATTCTGCA AGAGCGGGAA TACAGACTTC 1260
AGGCCCGCAT AGCTCATAGG ATACAAGAAC TGGAAAATCT GCCTGGCTCT TTGCCACCAG 1320
ATTTAAGAAC CAAAGCAACC GTGGAACTAA AAGCACTTCG GTTACTCAAT TTCCAGCGTC 1380
AGCTGAGACA GGAGGTGGTG GCCTGCATGC GCAGGGACAC GACCCTGGAG ACGGCTCTCA 1440
ACTCCAAAGC ATACAAACGG AGCAAGCGCC AGACTCTGAG AGAAGCTCGC ATGACCGAGA 1500
AGCTGGAGAA GCAGCAGAAG ATTGAGCAGG AGAGGAAACG CCGTCAGAAA CACCAGGAAT 1560
ACCTGAACAG TATTTTGCAA CATGCAAAAG ATTTTAAGGA ATATCATCGG TCTGTGGCCG 1620
GAAAGATCCA GAAGCTCTCC AAAGCAGTGG CAACTTGGCA TGCCAACACT GAAAGAGAGC 1680
AGAAGAAGGA GACAGAGCGG ATTGAAAAGG AGAGAATGCG GCGACTGATG GCTGAAGATG 1740
AGGAGGGTTA TAGAAAACTG ATTGATCAAA AGAAAGACAG GCGTTTAGCT TACCTTTTGC 1800
AGCAGACCGA TGAGTATGTA GCCAATCTGA CCAATCTGGT TTGGGAGCAC AAGCAAGCCC 1860
AGGCAGCCAA AGAGAAGAAG AAGAGGAGGA GGAGGAAGAA GAAGGCTGAG GAGAATGCAG 1920
AGGGTGGGGA GTCTGCCCTG GGACCGGATG GAGAGCCCAT AGATGAGAGC AGCCAGATGA 1980
GTGACCTCCC TGTCAAAGTG ACTCACACAG AAACCGGCAA GGTTCTGTTC GGACCAGAAG 2040
CACCCAAAGC AAGTCAGCTG GACGCCTGGC TGGAAATGAA TCCTGGTTAT GAAGTTGCCC 2100
CTAGATCTGA CAGTGAAGAG AGTGATTCTG ATTATGAGGA AGAGGATGAG GAAGAAGAGT 2160
CCAGTAGGCA GGAAACCGAA GAGAAAATAC TCCTGGATCC AAATAGCGAA GAAGTTTCTG 2220
AGAAGGATGC TAAGCAGATC ATTGAGACAG CTAAGCAAGA CGTGGATGAT GAATACAGCA 2280
TGCAGTACAG TGCCAGGGGC TCCCAGTCCT ACTACACCGT GGCTCATGCC ATCTCGGAGA 2340
GGGTGGAGAA ACAGTCTGCC CTCCTAATTA ATGGGACCCT AAAGCATTAC CAGCTCCAGG 2400
GCCTGGAATG GATGGTTTCC CTGTATAATA ACAACTTGAA CGGAATCTTA GCCGATGAAA 2460
TGGGGCTTGG AAAGACCATA CAGACCATTG CACTCATCAC TTATCTGATG GAGCACAAAA 2520
GACTCAATGG CCCCTATCTC ATCATTGTTC CCCTTTCGAC TCTATCTAAC TGGACATATG 2580
AATTTGACAA ATGGGCTCCT TCTGTGGTGA AGATTTCTTA CAAGGGTACT CCTGCCATGC 2640
GTCGCTCCCT TGTCCCCCAG CTACGGAGTG GCAAATTCAA TGTCCTCTTG ACTACTTATG 2700
AGTATATTAT AAAAGACAAG CACATTCTTG CAAAGATTCG GTGGAAATAC ATGATAGTGG 2760
ACGAAGGCCA CCGAATGAAG AATCACCACT GCAAGCTGAC TCAGGTCTTG AACACTCACT 2820
ATGTGGCCCC CAGAAGGATC CTCTTGACTG GGACCCCGCT GCAGAATAAG CTCCCTGAAC 2880
TCTGGGCCCT CCTCAACTTC CTCCTCCCAA CAATTTTTAA GAGCTGCAGC ACATTTGAAC 2940
AATGGTTCAA TGCTCCATTT GCCATGACTG GTGAAAGGGT GGACTTAAAT GAAGAAGAAA 3000
CTATATTGAT CATCAGGCGT CTACATAAGG TGTTAAGACC ATTTTTACTA AGGAGACTGA 3060
AGAAAGAAGT TGAATCCCAG CTTCCCGAAA AAGTGGAATA TGTGATCAAG TGTGACATGT 3120
CAGCTCTGCA GAAGATTCTG TATCGCCATA TGCAAGCCAA GGGGATCCTT CTCACAGATG 3180
GTTCTGAGAA AGATAAGAAG GGGAAAGGAG GTGCTAAGAC ACTTATGAAC ACTATTATGC 3240
AGTTGAGAAA AATCTGCAAC CACCCATATA TGTTTCAGCA CATTGAGGAA TCCTTTGCTG 3300
AACACCTAGG CTATTCAAAT GGGGTCATCA ATGGGGCTGA ACTGTATCGG GCCTCAGGGA 3360
AGTTTGAGCT GCTTGATCGT ATTCTGCCAA AATTGAGAGC GACTAATCAC CGAGTGCTGC 3420
TTTTCTGCCA GATGACATCT CTCATGACCA TCATGGAGGA TTATTTTGCT TTTCGGAACT 3480
TCCTTTACCT ACGCCTTGAT GGCACCACCA AGTCTGAAGA TCGTGCTGCT TTGCTGAAGA 3540
AATTCAATGA ACCTGGATCC CAGTATTTCA TTTTCTTGCT GAGCACAAGA GCTGGTGGCC 3600
TGGGCTTAAA TCTTCAGGCA GCTGATACAG TGGTCATCTT TGACAGCGAC TGGAATCCTC 3660
ATCAGGATCT GCAGGCCCAA GACCGAGCTC ACCGCATCGG GCAGCAGAAC GAGGTCCGGG 3720
TACTGAGGCT CTGTACCGTG AACAGCGTGG AGGAAAAGAT CCTCGCGGCC GCAAAATACA 3780
AGCTGAACGT GGATCAGAAA GTGATCCAGG CGGGCATGTT TGACCAAAAG TCTTCAAGCC 3840
ACGAGCGGAG GGCATTCCTG CAGGCCATCT TGGAGCATGA GGAGGAAAAT GAGGAAGAAG 3900
ATGAAGTACC GGACGATGAG ACTCTGAACC AAATGATTGC TCGACGAGAA GAAGAATTTG 3960
ACCTTTTTAT GCGGATGGAC ATGGACCGGC GGAGGGAAGA TGCCCGGAAC CCGAAACGGA 4020
AGCCCCGTTT AATGGAGGAG GATGAGCTGC CCTCCTGGAT CATTAAGGAT GACGCTGAAG 4080
TAGAAAGGCT CACCTGTGAA GAAGAGGAGG AGAAAATATT TGGGAGGGGG TCCCGCCAGC 4140
GCCGTGACGT GGACTACAGT GACGCCCTCA CGGAGAAGCA GTGGCTAAGG GCCATCGAAG 4200
ACGGCAATTT GGAGGAAATG GAAGAGGAAG TACGGCTTAA GAAGCGAAAA AGACGAAGAA 4260
ATGTGGATAA AGATCCTGCA AAAGAAGATG TGGAAAAAGC TAAGAAGAGA AGAGGCCGCC 4320
CTCCCGCTGA GAAACTGTCA CCAAATCCCC CCAAACTGAC AAAGCAGATG AACGCTATCA 4380
TCGATACTGT GATAAACTAC AAAGATAGGT GTAACGTGGA GAAGGTGCCC AGTAATTCTC 4440
AGTTGGAAAT AGAAGGAAAC AGTTCAGGGC GACAGCTCAG TGAAGTCTTC ATTCAGTTAC 4500
CTTCAAGGAA AGAATTACCA GAATACTATG AATTAATTAG GAAGCCAGTG GATTTCAAAA 4560
AAATAAAGGA AAGGATTCGT AATCATAAGT ACCGGAGCCT AGGCGACCTG GAGAAGGATG 4620
TCATGCTTCT CTGTCACAAC GCTCAGACGT TCAACCTGGA GGGATCCCAG ATCTATGAAG 4680
ACTCCATCGT CTTACAGTCA GTGTTTAAGA GTGCCCGGCA GAAAATTGCC AAAGAGGAAG 4740
AGAGTGAGGA TGAAAGCAAT GAAGAGGAGG AAGAGGAAGA TGAAGAAGAG TCAGAGTCCG 4800
AGGCAAAATC AGTCAAGGTG AAAATTAAGC TCAATAAAAA AGATGACAAA GGCCGGGACA 4860
AAGGGAAAGG CAAGAAAAGG CCAAATCGAG GAAAAGCCAA ACCTGTAGTG AGCGATTTTG 4920
ACAGCGATGA GGAGCAGGAT GAACGTGAAC AGTCAGAAGG AAGTGGGACG GATGATGAGT 4980
GATCAGTATG GACCTTTTTC CTTGGTAGAA CTGAATTCCT TCCTCCCCTG TCTCATTTCT 5040
ACCCAGTGAG TTCATTTGTC ATATAGGCAC TGGGTTGTTT CTATATCATC ATCGTCTATA 5100
AACTAGCTTT AGGATAGTGC CAGACAAACA TATGATATCA TGGTGTAAAA AACACACACA 5160
TACACAAATA TTTGTAACAT ATTGTGACCA AATGGGCCTC AAAGATTCAG ATTGAAACAA 5220
ACAAAAAGCT TTTGATGGAA AATATGTGGG TGGATAGTAT ATTTCTATGG GTGGGTCTAA 5280
TTTGGTAACG GTTTGATTGT GCCTGGTTTT ATCACCTGTT CAGATGAGAA GATTTTTGTC 5340
TTTTGTAGCA CTGATAACCA GGAGAAGCCA TTAAAAGCCA CTGGTTATTT TATTTTTCAT 5400
CAGGCAATTT TCGAGGTTTT TATTTGTTCG GTATTGTTTT TTTACACTGT GGTACATATA 5460
AGCAACTTTA ATAGGTGATA AATGTACAGT AGTTAGATTT CACCTGCATA TACATTTTTC 5520
CATTTTATGC TCTATGATCT GAACAAAAGC TTTTTGAATT GTATAAGATT TATGTCTACT 5580
GTAAACATTG CTTAATTTTT TTGCTCTTGA TTTAAAAAAA AGTTTTGTTG AAAGCGCTAT 5640
TGAATATTGC AATCTATATA GTGTATTGGA TGGCTTCTTT TGTCACCCTG ATCTCCTATG 5700
TTACCAATGT GTATCGTCTC CTTCTCCCTA AAGTGTACTT AATCTTTGCT TTCTTTGCAC 5760
AATGTCTTTG GTTGCAAGTC ATAAGCCTGA GGCAAATAAA ATTCCAGTAA TTTCGAAGAA 5820
TGTGGTGTTG GTGCTTTCCT AATAAAGAAA TAATTTAGCT TGACAAA 5868
Sequence Source Ensembl
Keyword

KW-0002--3D-structure
KW-0007--Acetylation
KW-0010--Activator
KW-0025--Alternative splicing
KW-0067--ATP-binding
KW-0103--Bromodomain
KW-0181--Complete proteome
KW-0225--Disease mutation
KW-0238--DNA-binding
KW-0347--Helicase
KW-0378--Hydrolase
KW-1063--Hypotrichosis
KW-0991--Mental retardation
KW-0524--Neurogenesis
KW-0547--Nucleotide-binding
KW-0539--Nucleus
KW-0597--Phosphoprotein
KW-0621--Polymorphism
KW-1185--Reference proteome
KW-1211--Schizophrenia
KW-0804--Transcription
KW-0805--Transcription regulation
--

Interpro

IPR006576--BRK_domain
IPR001487--Bromodomain
IPR018359--Bromodomain_CS
IPR014978--Gln-Leu-Gln_QLQ
IPR014001--Helicase_ATP-bd
IPR001650--Helicase_C
IPR014012--HSA_dom
IPR027417--P-loop_NTPase
IPR030088--SMARCA2
IPR029295--SnAC
IPR000330--SNF2_N

PROSITE

PS00633--BROMODOMAIN_1
PS50014--BROMODOMAIN_2
PS51192--HELICASE_ATP_BIND_1
PS51194--HELICASE_CTER
PS51204--HSA
PS51666--QLQ

Pfam

PF07533--BRK
PF00439--Bromodomain
PF00271--Helicase_C
PF07529--HSA
PF08880--QLQ
PF14619--SnAC
PF00176--SNF2_N

Gene Ontology

GO:0045111--C:intermediate filament cytoskeleton
GO:0043231--C:intracellular membrane-bounded organelle
GO:0071565--C:nBAF complex
GO:0071564--C:npBAF complex
GO:0000790--C:nuclear chromatin
GO:0005654--C:nucleoplasm
GO:0005634--C:nucleus
GO:0016514--C:SWI/SNF complex
GO:0005524--F:ATP binding
GO:0003682--F:chromatin binding
GO:0008094--F:DNA-dependent ATPase activity
GO:0004386--F:helicase activity
GO:0001105--F:RNA polymerase II transcription coactivator activity
GO:0003713--F:transcription coactivator activity
GO:0044212--F:transcription regulatory region DNA binding
GO:0006338--P:chromatin remodeling
GO:0030308--P:negative regulation of cell growth
GO:0008285--P:negative regulation of cell proliferation
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0045892--P:negative regulation of transcription, DNA-templated
GO:0007399--P:nervous system development
GO:0045944--P:positive regulation of transcription from RNA polymerase II promoter
GO:0045893--P:positive regulation of transcription, DNA-templated
GO:0006357--P:regulation of transcription from RNA polymerase II promoter
GO:0006355--P:regulation of transcription, DNA-templated
GO:0007286--P:spermatid development

Orthology
WERAM ID Ensembl Protein ID Species Identity E-value Score
WERAM-Caf-0024 ENSCAFP00000002979.4 Canis familiaris 96 0.0 2227
WERAM-Bot-0078 ENSBTAP00000035551.3 Bos taurus 96 0.0 2222
WERAM-Chs-0102 ENSCSAP00000004907.1 Chlorocebus sabaeus 97 0.0 2193
WERAM-Sus-0035 ENSSSCP00000005624.2 Sus scrofa 93 0.0 2127
WERAM-Aim-0137 ENSAMEP00000013109.1 Ailuropoda melanoleuca 100 0.0 2075
WERAM-Nol-0088 ENSNLEP00000010477.1 Nomascus leucogenys 100 0.0 2070
WERAM-Mup-0058 ENSMPUP00000005133.1 Mustela putorius furo 100 0.0 2067
WERAM-Ran-0079 ENSRNOP00000016740.3 Rattus norvegicus 100 0.0 2066
WERAM-Tut-0024 ENSTTRP00000001909.1 Tursiops truncatus 100 0.0 2065
WERAM-Orc-0059 ENSOCUP00000016214.2 Oryctolagus cuniculus 98 0.0 2021
WERAM-Cap-0063 ENSCPOP00000004930.2 Cavia porcellus 98 0.0 2021
WERAM-Ict-0071 ENSSTOP00000006128.2 Ictidomys tridecemlineatus 98 0.0 2021
WERAM-Otg-0178 ENSOGAP00000015276.2 Otolemur garnettii 98 0.0 2018
WERAM-Dan-0051 ENSDNOP00000004971.3 Dasypus novemcinctus 98 0.0 2014
WERAM-Mum-0064 ENSMUSP00000025862.7 Mus musculus 98 0.0 2013
WERAM-Mod-0027 ENSMODP00000004375.3 Monodelphis domestica 97 0.0 2009
WERAM-Sah-0078 ENSSHAP00000009101.1 Sarcophilus harrisii 97 0.0 2008
WERAM-Poa-0182 ENSPPYP00000021564.2 Pongo abelii 98 0.0 2003
WERAM-Loa-0128 ENSLAFP00000011784.3 Loxodonta africana 98 0.0 2003
WERAM-Ova-0136 ENSOARP00000014227.1 Ovis aries 98 0.0 2002
WERAM-Tag-0080 ENSTGUP00000005661.1 Taeniopygia guttata 96 0.0 1998
WERAM-Fia-0131 ENSFALP00000010890.1 Ficedula albicollis 96 0.0 1996
WERAM-Pes-0045 ENSPSIP00000006802.1 Pelodiscus sinensis 96 0.0 1985
WERAM-Gaga-0103 ENSGALP00000016509.3 Gallus gallus 93 0.0 1973
WERAM-Anc-0020 ENSACAP00000002825.3 Anolis carolinensis 95 0.0 1971
WERAM-Fec-0018 ENSFCAP00000001456.3 Felis catus 97 0.0 1969
WERAM-Gog-0005 ENSGGOP00000000508.2 Gorilla gorilla 96 0.0 1962
WERAM-Leo-0110 ENSLOCP00000014138.1 Lepisosteus oculatus 91 0.0 1920
WERAM-Eqc-0203 ENSECAP00000021944.1 Equus caballus 98 0.0 1899
WERAM-Myl-0029 ENSMLUP00000002143.2 Myotis lucifugus 93 0.0 1898
WERAM-Ocp-0119 ENSOPRP00000012321.1 Ochotona princeps 93 0.0 1872
WERAM-Dar-0024 ENSDARP00000041411.7 Danio rerio 89 0.0 1862
WERAM-Xet-0101 ENSXETP00000033490.3 Xenopus tropicalis 89 0.0 1851
WERAM-Orn-0175 ENSONIP00000017804.1 Oreochromis niloticus 88 0.0 1838
WERAM-Pof-0026 ENSPFOP00000002687.2 Poecilia formosa 87 0.0 1820
WERAM-Vip-0011 ENSVPAP00000001111.1 Vicugna pacos 92 0.0 1818
WERAM-Tar-0192 ENSTRUP00000039929.1 Takifugu rubripes 87 0.0 1808
WERAM-Mae-0090 ENSMEUP00000008983.1 Macropus eugenii 91 0.0 1787
WERAM-Gaa-0147 ENSGACP00000019132.2 Gasterosteus aculeatus 86 0.0 1785
WERAM-Gam-0154 ENSGMOP00000015257.1 Gadus morhua 84 0.0 1761
WERAM-Caj-0065 ENSCJAP00000011400.2 Callithrix jacchus 82 0.0 1760
WERAM-Orla-0213 ENSORLP00000025785.1 Oryzias latipes 82 0.0 1756
WERAM-Ptv-0007 ENSPVAP00000000854.1 Pteropus vampyrus 100 0.0 1754
WERAM-Xim-0079 ENSXMAP00000007115.1 Xiphophorus maculatus 82 0.0 1730
WERAM-Ten-0053 ENSTNIP00000007185.1 Tetraodon nigroviridis 80 0.0 1706
WERAM-Pem-0051 ENSPMAP00000006008.1 Petromyzon marinus 79 0.0 1700
WERAM-Anp-0144 ENSAPLP00000015434.1 Anas platyrhynchos 79 0.0 1649
WERAM-Paa-0203 ENSPANP00000019261.1 Papio anubis 93 0.0 1534
WERAM-Soa-0073 ENSSARP00000007184.1 Sorex araneus 88 0.0 1503
WERAM-Tas-0036 ENSTSYP00000003569.1 Tarsius syrichta 90 0.0 1441
WERAM-Ect-0091 ENSETEP00000010838.1 Echinops telfairi 73 0.0 1328
WERAM-Asm-0116 ENSAMXP00000011579.1 Astyanax mexicanus 69 0.0 1325
WERAM-Cis-0043 ENSCSAVP00000009441.1 Ciona savignyi 63 0.0 1295
WERAM-Mam-0101 ENSMMUP00000015797.2 Macaca mulatta 84 0.0 1292
WERAM-Drm-0001 FBpp0075281 Drosophila melanogaster 62 0.0 1284
WERAM-Chh-0034 ENSCHOP00000003837.1 Choloepus hoffmanni 91 0.0 1249
WERAM-Mim-0096 ENSMICP00000008960.1 Microcebus murinus 84 0.0 1132
WERAM-Cae-0016 F01G4.1 Caenorhabditis elegans 54 0.0 1074
WERAM-Prc-0143 ENSPCAP00000013247.1 Procavia capensis 69 0.0 920
WERAM-Tum-0012 CAZ81450 Tuber melanosporum 52 0.0 781
WERAM-Ved-0024 EGY15057 Verticillium dahliae 51 0.0 778
WERAM-Trr-0022 EGR50940 Trichoderma reesei 50 0.0 777
WERAM-Asni-0035 CADANGAP00013288 Aspergillus niger 51 0.0 777
WERAM-Trv-0020 EHK16775 Trichoderma virens 50 0.0 773
WERAM-Scj-0039 EEB09542 Schizosaccharomyces japonicus 53 0.0 773
WERAM-Mao-0021 MGG_06388T0 Magnaporthe oryzae 50 0.0 769
WERAM-Asn-0034 CADANIAP00008970 Aspergillus nidulans 51 0.0 768
WERAM-Coi-0026 EAS30564 Coccidioides immitis 50 0.0 768
WERAM-Zyt-0031 Mycgr3P74992 Zymoseptoria tritici 49 0.0 768
WERAM-Ast-0030 CADATEAP00008674 Aspergillus terreus 50 0.0 766
WERAM-Asfu-0028 CADAFUAP00006226 Aspergillus fumigatus 51 0.0 764
WERAM-Aso-0019 CADAORAP00003972 Aspergillus oryzae 51 0.0 763
WERAM-Asc-0004 CADACLAP00000822 Aspergillus clavatus 50 0.0 760
WERAM-Scp-0003 SPAC1250.01.1:pep Schizosaccharomyces pombe 52 0.0 759
WERAM-Pyt-0040 EFQ85893 Pyrenophora teres 50 0.0 757
WERAM-Pytr-0005 EDU40575 Pyrenophora triticirepentis 50 0.0 757
WERAM-Yal-0010 CAG81384 Yarrowia lipolytica 50 0.0 751
WERAM-Asf-0030 CADAFLAP00010870 Aspergillus flavus 51 0.0 751
WERAM-Lem-0011 CBY00787 Leptosphaeria maculans 49 0.0 741
WERAM-Scs-0025 EDO04534 Sclerotinia sclerotiorum 60 0.0 724
WERAM-Crn-0040 AAW46162 Cryptococcus neoformans 48 0.0 722
WERAM-Nec-0028 EFNCRP00000006203 Neurospora crassa 58 0.0 720
WERAM-Spr-0003 CBQ70591 Sporisorium reilianum 59 0.0 719
WERAM-Gag-0023 GGTG_08193T0 Gaeumannomyces graminis 58 0.0 719
WERAM-Usm-0006 UM01183P0 Ustilago maydis 58 0.0 719
WERAM-Map-0027 MAPG_07994T0 Magnaporthe poae 59 0.0 715
WERAM-Miv-0005 MVLG_00286T0 Microbotryum violaceum 53 0.0 714
WERAM-Kop-0033 CAY72190 Komagataella pastoris 55 0.0 707
WERAM-Sac-0044 YOR290C Saccharomyces cerevisiae 56 0.0 701
WERAM-Caa-0009 KGT71213 Candida albicans 54 0.0 697
WERAM-Phn-0020 SNOT_09308 Phaeosphaeria nodorum 49 0.0 697
WERAM-Asg-0027 AAS53933 Ashbya gossypii 55 0.0 697
WERAM-Kll-0025 CAG97992 Kluyveromyces lactis 56 0.0 690
WERAM-Pug-0020 EFP83552 Puccinia graminis 57 0.0 689
WERAM-Cag-0033 CAG62532 Candida glabrata 55 0.0 686
WERAM-Mel-0020 EGG12815 Melampsora laricipopulina 56 0.0 674
WERAM-Dio-0151 ENSDORP00000013957.1 Dipodomys ordii 93 0.0 654
WERAM-Cii-0048 ENSCINP00000018744.3 Ciona intestinalis 64 8e-168 589
WERAM-Lac-0007 ENSLACP00000000983.1 Latimeria chalumnae 85 6e-165 580
WERAM-Put-0005 PTTG_03431P0 Puccinia triticina 52 1e-164 578
WERAM-Mua-0150 GSMUA_AchrUn_randomP07690_001 Musa acuminata 47 7e-128 456
WERAM-Pot-0141 POPTR_0014s08230.1 Populus trichocarpa 46 8e-128 456
WERAM-Amt-0015 ERM94966 Amborella trichopoda 44 2e-127 454
WERAM-Viv-0096 VIT_15s0046g02290.t01 Vitis vinifera 46 3e-126 451
WERAM-Php-0027 PP1S158_37V6.1 Physcomitrella patens 45 3e-126 451
WERAM-Sem-0125 EFJ33371 Selaginella moellendorffii 44 6e-126 450
WERAM-Art-0059 AT2G46020.2 Arabidopsis thaliana 45 7e-126 450
WERAM-Arl-0079 fgenesh2_kg.4__ 2806__ AT2G46020.1 Arabidopsis lyrata 45 7e-126 450
WERAM-Met-0151 AES80217 Medicago truncatula 45 4e-125 447
WERAM-Thc-0016 EOX95924 Theobroma cacao 44 5e-125 447
WERAM-Sol-0014 Solyc01g094800.2.1 Solanum lycopersicum 44 4e-123 441
WERAM-Glm-0017 GLYMA02G45000.1 Glycine max 43 1e-119 429
WERAM-Bro-0171 Bo9g022450.1 Brassica oleracea 44 1e-118 426
WERAM-Brr-0186 Bra037208.1-P Brassica rapa 46 2e-118 425
WERAM-Sob-0039 Sb02g041910.1 Sorghum bicolor 43 3e-115 414
WERAM-Meg-0097 ENSMGAP00000009319.2 Meleagris gallopavo 45 3e-113 408
WERAM-Pat-0057 ENSPTRP00000012779.4 Pan troglodytes 45 5e-113 407
WERAM-Ora-0044 ENSOANP00000006945.1 Ornithorhynchus anatinus 45 1e-111 402
Created Date 25-Jun-2016