WERAM Information

Tag Content
WERAM ID WERAM-Hos-0081
Ensembl Protein ID ENSP00000349508.2
Uniprot Accession Q14839; CHD4_HUMAN; Q8IXZ5
Genbank Protein ID NP_001264.2; NP_001284482.1; XP_006719021.1
Protein Name Chromodomain-helicase-DNA-binding protein 4
Genbank Nucleotide ID NM_001273.3; NM_001297553.1; XM_006718958.1
Gene Name CHD4
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSG00000111642.14 ENST00000357008.6 ENSP00000349508.2
ENSG00000111642.14 ENST00000544484.5 ENSP00000440392.1
ENSG00000111642.14 ENST00000544040.5 ENSP00000440542.1
Details
Type Family Domain Substrates AA References (PMIDs)
Me_Reader DCD Chromo1 H3K9me3 K 24576085
Me_Reader PHD PHD1 H3K9me3 K 24576085
Status Reviewed
Classification
Type Family E-value Score Start End
Me_Reader PHD 5.00e-19 70.5 371 494
Me_Reader DCD 2.60e-40 123.4 542 578
Organism Homo sapiens
NCBI Taxa ID 9606
Functional Description
(View)		 Component of the histone deacetylase NuRD complex which participates in the remodeling of chromatin by deacetylating histones.
Domain Profile
  Me_Reader PHD
            PHD.txt   2 tiClvCgkddegekemvqCdeCddwfHlkCvklplsslpegkswyCpsCke 52 
                        ++C vC +++ +   ++ Cd+C++++H+ C+++ ++++peg +w Cp+C++
  ENSP00000349508.2 371 DYCEVC-QQGGE---IILCDTCPRAYHMVCLDPDMEKAPEG-KWSCPHCEK 416
                        69****.55444...9*************************.*******87 PP
            PHD.txt   2 tiClvCgkddegekemvqCdeCddwfHlkCvklplsslpegkswyCpsCk 51 
                        ++C+vC kd+ +   +++Cd+C+  +H++C+++pl ++p+g +w+Cp+C+
  ENSP00000349508.2 450 EFCRVC-KDGGE---LLCCDTCPSSYHIHCLNPPLPEIPNG-EWLCPRCT 494
                        69****.66665...9*************************.*******7 PP
  Me_Reader DCD
       Chromo-2.txt  18 hyLikWkdlpYdeaswesatvenkkypqlvqsfyeer 54 
                        ++++kW+++ Y  +sw+s+      ++ +  +++ ++
  ENSP00000349508.2 542 QFFVKWQGMSYWHCSWVSELQLELHCQVMFRNYQRKN 578
                        79****************9999999999988888665 PP
       Chromo-2.txt   1 mmverIinhsvdkkGelhyLikWkdlpYdeaswesatvenkkypqlvqsfyeeresmrgee 61 
                        mm++rI+nhsvdkkG++hyLikW+dlpYd+aswes++ve+++y++++qs++++re+mrgee
  ENSP00000349508.2 622 MMIHRILNHSVDKKGHVHYLIKWRDLPYDQASWESEDVEIQDYDLFKQSYWNHRELMRGEE 682
                        8**********************************************************98 PP
Protein Sequence
(Fasta)		MASGLGSPSP CSAGSEEEDM DALLNNSLPP PHPENEEDPE EDLSETETPK LKKKKKPKKP 60
RDPKIPKSKR QKKERMLLCR QLGDSSGEGP EFVEEEEEVA LRSDSEGSDY TPGKKKKKKL 120
GPKKEKKSKS KRKEEEEEED DDDDSKEPKS SAQLLEDWGM EDIDHVFSEE DYRTLTNYKA 180
FSQFVRPLIA AKNPKIAVSK MMMVLGAKWR EFSTNNPFKG SSGASVAAAA AAAVAVVESM 240
VTATEVAPPP PPVEVPIRKA KTKEGKGPNA RRKPKGSPRV PDAKKPKPKK VAPLKIKLGG 300
FGSKRKRSSS EDDDLDVESD FDDASINSYS VSDGSTSRSS RSRKKLRTTK KKKKGEEEVT 360
AVDGYETDHQ DYCEVCQQGG EIILCDTCPR AYHMVCLDPD MEKAPEGKWS CPHCEKEGIQ 420
WEAKEDNSEG EEILEEVGGD LEEEDDHHME FCRVCKDGGE LLCCDTCPSS YHIHCLNPPL 480
PEIPNGEWLC PRCTCPALKG KVQKILIWKW GQPPSPTPVP RPPDADPNTP SPKPLEGRPE 540
RQFFVKWQGM SYWHCSWVSE LQLELHCQVM FRNYQRKNDM DEPPSGDFGG DEEKSRKRKN 600
KDPKFAEMEE RFYRYGIKPE WMMIHRILNH SVDKKGHVHY LIKWRDLPYD QASWESEDVE 660
IQDYDLFKQS YWNHRELMRG EEGRPGKKLK KVKLRKLERP PETPTVDPTV KYERQPEYLD 720
ATGGTLHPYQ MEGLNWLRFS WAQGTDTILA DEMGLGKTVQ TAVFLYSLYK EGHSKGPFLV 780
SAPLSTIINW EREFEMWAPD MYVVTYVGDK DSRAIIRENE FSFEDNAIRG GKKASRMKKE 840
ASVKFHVLLT SYELITIDMA ILGSIDWACL IVDEAHRLKN NQSKFFRVLN GYSLQHKLLL 900
TGTPLQNNLE ELFHLLNFLT PERFHNLEGF LEEFADIAKE DQIKKLHDML GPHMLRRLKA 960
DVFKNMPSKT ELIVRVELSP MQKKYYKYIL TRNFEALNAR GGGNQVSLLN VVMDLKKCCN 1020
HPYLFPVAAM EAPKMPNGMY DGSALIRASG KLLLLQKMLK NLKEGGHRVL IFSQMTKMLD 1080
LLEDFLEHEG YKYERIDGGI TGNMRQEAID RFNAPGAQQF CFLLSTRAGG LGINLATADT 1140
VIIYDSDWNP HNDIQAFSRA HRIGQNKKVM IYRFVTRASV EERITQVAKK KMMLTHLVVR 1200
PGLGSKTGSM SKQELDDILK FGTEELFKDE ATDGGGDNKE GEDSSVIHYD DKAIERLLDR 1260
NQDETEDTEL QGMNEYLSSF KVAQYVVREE EMGEEEEVER EIIKQEESVD PDYWEKLLRH 1320
HYEQQQEDLA RNLGKGKRIR KQVNYNDGSQ EDRDWQDDQS DNQSDYSVAS EEGDEDFDER 1380
SEAPRRPSRK GLRNDKDKPL PPLLARVGGN IEVLGFNARQ RKAFLNAIMR YGMPPQDAFT 1440
TQWLVRDLRG KSEKEFKAYV SLFMRHLCEP GADGAETFAD GVPREGLSRQ HVLTRIGVMS 1500
LIRKKVQEFE HVNGRWSMPE LAEVEENKKM SQPGSPSPKT PTPSTPGDTQ PNTPAPVPPA 1560
EDGIKIEENS LKEEESIEGE KEVKSTAPET AIECTQAPAP ASEDEKVVVE PPEGEEKVEK 1620
AEVKERTEEP METEPKGAAD VEKVEEKSAI DLTPIVVEDK EEKKEEEEKK EVMLQNGETP 1680
KDLNDEKQKK NIKQRFMFNI ADGGFTELHS LWQNEERAAT VTKKTYEIWH RRHDYWLLAG 1740
IINHGYARWQ DIQNDPRYAI LNEPFKGEMN RGNFLEIKNK FLARRFKLLE QALVIEEQLR 1800
RAAYLNMSED PSHPSMALNT RFAEVECLAE SHQHLSKESM AGNKPANAVL HKVLKQLEEL 1860
LSDMKADVTR LPATIARIPP VAVRLQMSER NILSRLANRA PEPTPQQVAQ QQ 1912
Nucleotide Sequence
(Fasta)		ATTTTCCCCC CTTCGGCCGC GGCGAGGAGG AGCCGGAGCG GGAGTGACAC CGAGCCGGAC 60
CCAGCGCGAC CTGCGGCGGC TCCGGGTGAC TCGGGCCAGT GTAGAGGTCC TCAGGCCGCC 120
GGCAGGAGCA GCTGGGCCAA TTCCCTGGCC GGGAGCGGAA GGGGATGGCG TCGGGCCTGG 180
GCTCCCCGTC CCCCTGCTCG GCGGGCAGTG AGGAGGAGGA TATGGATGCA CTTTTGAACA 240
ACAGCCTGCC CCCACCCCAC CCAGAAAATG AAGAGGACCC AGAAGAGGAT TTGTCAGAAA 300
CAGAGACTCC AAAGCTCAAG AAGAAGAAAA AGCCTAAGAA ACCTCGGGAC CCTAAAATCC 360
CTAAGAGCAA GCGCCAAAAA AAGGAGCGTA TGCTCTTATG CCGGCAGCTG GGGGACAGCT 420
CTGGGGAGGG GCCAGAGTTT GTGGAGGAGG AGGAAGAGGT GGCTCTGCGC TCAGACAGTG 480
AGGGCAGCGA CTATACTCCT GGCAAGAAGA AGAAGAAGAA GCTTGGACCT AAGAAAGAGA 540
AGAAGAGCAA ATCCAAGCGG AAGGAGGAGG AGGAGGAGGA GGATGATGAT GATGATTCAA 600
AGGAGCCTAA ATCATCTGCT CAGCTCCTGG AAGACTGGGG CATGGAAGAC ATTGACCACG 660
TGTTCTCAGA GGAGGATTAT CGAACCCTCA CCAACTACAA GGCCTTCAGC CAGTTTGTCA 720
GACCCCTCAT TGCTGCCAAA AATCCCAAGA TTGCTGTCTC CAAGATGATG ATGGTTTTGG 780
GTGCAAAATG GCGGGAGTTC AGTACCAATA ACCCCTTCAA AGGCAGTTCT GGGGCATCAG 840
TGGCAGCTGC GGCAGCAGCA GCGGTAGCTG TGGTGGAGAG CATGGTGACA GCCACTGAGG 900
TTGCACCACC ACCTCCCCCT GTGGAGGTGC CTATCCGCAA GGCCAAGACC AAGGAGGGCA 960
AAGGTCCCAA TGCTCGGAGG AAGCCCAAGG GCAGCCCTCG TGTACCTGAT GCCAAGAAGC 1020
CTAAACCCAA GAAAGTAGCT CCCCTGAAAA TCAAGCTGGG AGGTTTTGGT TCCAAGCGTA 1080
AGAGATCCTC GAGTGAGGAT GATGACTTAG ATGTGGAATC TGACTTCGAT GATGCCAGTA 1140
TCAATAGCTA TTCTGTTTCT GATGGTTCCA CCAGCCGTAG TAGCCGCAGC CGCAAGAAAC 1200
TCCGAACCAC TAAAAAGAAA AAGAAAGGCG AGGAGGAGGT GACTGCTGTG GATGGTTATG 1260
AGACAGACCA CCAGGACTAT TGCGAGGTGT GCCAGCAAGG CGGTGAGATC ATCCTGTGTG 1320
ATACCTGTCC CCGTGCTTAC CACATGGTCT GCCTGGATCC CGACATGGAG AAGGCTCCCG 1380
AGGGCAAGTG GAGCTGCCCA CACTGCGAGA AGGAAGGCAT CCAGTGGGAA GCTAAAGAGG 1440
ACAATTCGGA GGGTGAGGAG ATCCTGGAAG AGGTTGGGGG AGACCTCGAA GAGGAGGATG 1500
ACCACCATAT GGAATTCTGT CGGGTCTGCA AGGATGGTGG GGAACTGCTC TGCTGTGATA 1560
CCTGTCCTTC TTCCTACCAC ATCCACTGCC TGAATCCCCC ACTTCCAGAG ATCCCCAACG 1620
GTGAATGGCT CTGTCCCCGT TGTACGTGTC CAGCTCTGAA GGGCAAAGTG CAGAAGATCC 1680
TAATCTGGAA GTGGGGTCAG CCACCATCTC CCACACCAGT GCCTCGGCCT CCAGATGCTG 1740
ATCCCAACAC GCCCTCCCCA AAGCCCTTGG AGGGGCGGCC AGAGCGGCAG TTCTTTGTGA 1800
AATGGCAAGG CATGTCTTAC TGGCACTGCT CCTGGGTTTC TGAACTGCAG CTGGAGCTGC 1860
ACTGTCAGGT GATGTTCCGA AACTATCAGC GGAAGAATGA TATGGATGAG CCACCTTCTG 1920
GGGACTTTGG TGGTGATGAA GAGAAAAGCC GAAAGCGAAA GAACAAGGAC CCTAAATTTG 1980
CAGAGATGGA GGAACGCTTC TATCGCTATG GGATAAAACC CGAGTGGATG ATGATCCACC 2040
GAATCCTCAA CCACAGTGTG GACAAGAAGG GCCACGTCCA CTACTTGATC AAGTGGCGGG 2100
ACTTACCTTA CGATCAGGCT TCTTGGGAGA GTGAGGATGT GGAGATCCAG GATTACGACC 2160
TGTTCAAGCA GAGCTATTGG AATCACAGGG AGTTAATGAG GGGTGAGGAA GGCCGACCAG 2220
GCAAGAAGCT CAAGAAGGTG AAGCTTCGGA AGTTGGAGAG GCCTCCAGAA ACGCCAACAG 2280
TTGATCCAAC AGTGAAGTAT GAGCGACAGC CAGAGTACCT GGATGCTACA GGTGGAACCC 2340
TGCACCCCTA TCAAATGGAG GGCCTGAATT GGTTGCGCTT CTCCTGGGCT CAGGGCACTG 2400
ACACCATCTT GGCTGATGAG ATGGGCCTTG GGAAAACTGT ACAGACAGCA GTCTTCCTGT 2460
ATTCCCTTTA CAAGGAGGGT CATTCCAAAG GCCCCTTCCT AGTGAGCGCC CCTCTTTCTA 2520
CCATCATCAA CTGGGAGCGG GAGTTTGAAA TGTGGGCTCC AGACATGTAT GTCGTAACCT 2580
ATGTGGGTGA CAAGGACAGC CGTGCCATCA TCCGAGAGAA TGAGTTCTCC TTTGAAGACA 2640
ATGCCATTCG TGGTGGCAAG AAGGCCTCCC GCATGAAGAA AGAGGCATCT GTGAAATTCC 2700
ATGTGCTGCT GACATCCTAT GAATTGATCA CCATTGACAT GGCTATTTTG GGCTCTATTG 2760
ATTGGGCCTG CCTCATCGTG GATGAAGCCC ATCGGCTGAA GAACAATCAG TCTAAGTTCT 2820
TCCGGGTATT GAATGGTTAC TCACTCCAGC ACAAGCTGTT GCTGACTGGG ACACCATTAC 2880
AAAACAATCT GGAAGAGTTG TTTCATCTGC TCAACTTTCT CACCCCCGAG AGGTTCCACA 2940
ATTTGGAAGG TTTTTTGGAG GAGTTTGCTG ACATTGCCAA GGAGGACCAG ATAAAAAAAC 3000
TGCATGACAT GCTGGGGCCG CACATGTTGC GGCGGCTCAA AGCCGATGTG TTCAAGAACA 3060
TGCCCTCCAA GACAGAACTA ATTGTGCGTG TGGAGCTGAG CCCTATGCAG AAGAAATACT 3120
ACAAGTACAT CCTCACTCGA AATTTTGAAG CACTCAATGC CCGAGGTGGT GGCAACCAGG 3180
TGTCTCTGCT GAATGTGGTG ATGGATCTTA AGAAGTGCTG CAACCATCCA TACCTCTTCC 3240
CTGTGGCTGC AATGGAAGCT CCTAAGATGC CTAATGGCAT GTATGATGGC AGTGCCCTAA 3300
TCAGAGCATC TGGGAAATTA TTGCTGCTGC AGAAAATGCT CAAGAACCTT AAGGAGGGTG 3360
GGCATCGTGT ACTCATCTTT TCCCAGATGA CCAAGATGCT AGACCTGCTA GAGGATTTCT 3420
TGGAACATGA AGGTTATAAA TACGAACGCA TCGATGGTGG AATCACTGGG AACATGCGGC 3480
AAGAGGCCAT TGACCGCTTC AATGCACCGG GTGCTCAGCA GTTCTGCTTC TTGCTTTCCA 3540
CTCGAGCTGG GGGCCTTGGA ATCAATCTGG CCACTGCTGA CACAGTTATT ATCTATGACT 3600
CTGACTGGAA CCCCCATAAT GACATTCAGG CCTTTAGCAG AGCTCACCGG ATTGGGCAAA 3660
ATAAAAAGGT AATGATCTAC CGGTTTGTGA CCCGTGCGTC AGTGGAGGAG CGCATCACGC 3720
AGGTGGCAAA GAAGAAAATG ATGCTGACGC ATCTAGTGGT GCGGCCTGGG CTGGGCTCCA 3780
AGACTGGATC TATGTCCAAA CAGGAGCTTG ATGATATCCT CAAATTTGGC ACTGAGGAAC 3840
TATTCAAGGA TGAAGCCACT GATGGAGGAG GAGACAACAA AGAGGGAGAA GATAGCAGTG 3900
TTATCCACTA CGATGATAAG GCCATTGAAC GGCTGCTAGA CCGTAACCAG GATGAGACTG 3960
AAGACACAGA ATTGCAGGGC ATGAATGAAT ATTTGAGCTC ATTCAAAGTG GCCCAGTATG 4020
TGGTACGGGA AGAAGAAATG GGGGAGGAAG AGGAGGTAGA ACGGGAAATC ATTAAACAGG 4080
AAGAAAGTGT GGATCCTGAC TACTGGGAGA AATTGCTGCG GCACCATTAT GAGCAGCAGC 4140
AAGAAGATCT AGCCCGAAAT CTGGGCAAAG GAAAAAGAAT CCGTAAACAG GTCAACTACA 4200
ATGATGGCTC CCAGGAGGAC CGAGATTGGC AGGACGACCA GTCCGACAAC CAGTCCGATT 4260
ACTCAGTGGC TTCAGAGGAA GGTGATGAAG ACTTTGATGA ACGTTCAGAA GCTCCCCGTA 4320
GGCCCAGTCG TAAGGGCCTG CGGAATGATA AAGATAAGCC ATTGCCTCCT CTGTTGGCCC 4380
GTGTTGGTGG GAATATTGAA GTACTTGGTT TTAATGCTCG TCAGCGAAAA GCCTTTCTTA 4440
ATGCAATTAT GCGATATGGT ATGCCACCTC AGGATGCTTT TACTACCCAG TGGCTTGTAA 4500
GAGACCTGCG AGGCAAATCA GAGAAAGAGT TCAAGGCATA TGTCTCTCTT TTCATGCGGC 4560
ATTTATGTGA GCCGGGGGCA GATGGGGCTG AGACCTTTGC TGATGGTGTC CCCCGAGAAG 4620
GCCTGTCTCG CCAGCATGTC CTTACTAGAA TTGGTGTTAT GTCTTTGATT CGCAAGAAGG 4680
TTCAGGAGTT TGAACATGTT AATGGGCGCT GGAGCATGCC TGAACTGGCT GAGGTGGAGG 4740
AAAACAAGAA GATGTCCCAG CCAGGGTCAC CCTCCCCAAA AACTCCTACA CCCTCCACTC 4800
CAGGGGACAC GCAGCCCAAC ACTCCTGCAC CTGTCCCACC TGCTGAAGAT GGGATAAAAA 4860
TAGAGGAAAA TAGCCTCAAA GAAGAAGAGA GCATAGAAGG AGAAAAGGAG GTTAAATCTA 4920
CAGCCCCTGA GACTGCCATT GAGTGTACAC AGGCCCCTGC CCCTGCCTCA GAGGATGAAA 4980
AGGTCGTTGT TGAACCCCCT GAGGGAGAGG AGAAAGTGGA AAAGGCAGAG GTGAAGGAGA 5040
GAACAGAGGA ACCTATGGAG ACAGAGCCCA AAGGTGCTGC TGATGTAGAG AAGGTGGAGG 5100
AAAAGTCAGC AATAGATCTG ACCCCTATTG TGGTAGAAGA CAAAGAAGAG AAGAAAGAAG 5160
AAGAAGAGAA AAAAGAGGTG ATGCTTCAGA ATGGAGAGAC CCCCAAGGAC CTGAATGATG 5220
AGAAACAGAA GAAAAATATT AAACAACGTT TCATGTTTAA CATTGCAGAT GGTGGTTTTA 5280
CTGAGTTGCA CTCCCTTTGG CAGAATGAAG AGCGGGCAGC CACAGTTACC AAGAAGACTT 5340
ATGAGATCTG GCATCGACGG CATGACTACT GGCTGCTAGC CGGCATTATA AACCATGGCT 5400
ATGCCCGGTG GCAAGACATC CAGAATGACC CACGCTATGC CATCCTCAAT GAGCCTTTCA 5460
AGGGTGAAAT GAACCGTGGC AATTTCTTAG AGATCAAGAA TAAATTTCTA GCTCGAAGGT 5520
TTAAGCTCTT AGAACAAGCT CTGGTGATTG AGGAACAGCT GCGCCGGGCT GCTTACTTGA 5580
ACATGTCAGA AGACCCTTCT CACCCTTCCA TGGCCCTCAA CACCCGCTTT GCTGAGGTGG 5640
AGTGTTTGGC GGAAAGTCAT CAGCACCTGT CCAAGGAGTC AATGGCAGGA AACAAGCCAG 5700
CCAATGCAGT CCTGCACAAA GTTCTGAAAC AGCTGGAAGA ACTGCTGAGT GACATGAAAG 5760
CTGATGTGAC TCGACTCCCA GCTACCATTG CCCGAATTCC CCCAGTTGCT GTGAGGTTAC 5820
AGATGTCAGA GCGTAACATT CTCAGCCGCC TGGCAAACCG GGCACCCGAA CCTACCCCAC 5880
AGCAGGTAGC CCAGCAGCAG TGAAGATGCA GACTGATACC ACCTCCACCG CTGAGCAGTG 5940
ACCTTCCTCA CTTTCTCTTG TCCCAGCTTC TCCCCTGGGG GCCTGAGAGA CCCTCACCTT 6000
CCTTCTGCCC ATCTTCCATG TTGTAAAGGA ACAGCCCCAG TGCACTGGGG GAGGGGAGGG 6060
AGTGAGGGGC AGTGGTGCCC TTCCTGCAGA AGAGACATGC AGCAGTAGCG CTGGCGCCAT 6120
CTGCAGGAGC TGGCGGGCTG GCCTTCTGGA CCCTGGCTTC TCCCCACTGT AACGCCTGTT 6180
ACACACAAAC TGTTGTGGGT TCCTGCCAGG CTTGAAGAAA ATGATCTGAA TTTTTTCCTC 6240
CTTTTGGTTT TATTTTGTTG GTTTATTTTG TGTTTTCTTT TCTCCTTTTT GGGGGGTATT 6300
CAGAGTGGGC TGGGCCCCTG GGCGAGACAC AGCTACCTCT GTTGGCATCT TTTTAATACC 6360
AGGAACCCAG CGGCTCTAGC CACTGAGCGG CTAAATGAAA TAAAGTGGAA AAAAAAAAAA 6420
AGGAAAAAAC CAAAAGCATA AAAAACCACA GCAAATTTCT TGATGAAAAT TGAAAATAAA 6480
AGTTTCCTTG TATTTT 6497
Sequence Source Ensembl
Keyword

KW-0002--3D-structure
KW-0007--Acetylation
KW-0025--Alternative splicing
KW-0067--ATP-binding
KW-0156--Chromatin regulator
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0206--Cytoskeleton
KW-0238--DNA-binding
KW-0347--Helicase
KW-0378--Hydrolase
KW-1017--Isopeptide bond
KW-0479--Metal-binding
KW-0547--Nucleotide-binding
KW-0539--Nucleus
KW-0597--Phosphoprotein
KW-0621--Polymorphism
KW-1185--Reference proteome
KW-0677--Repeat
KW-0804--Transcription
KW-0805--Transcription regulation
KW-0832--Ubl conjugation
KW-0862--Zinc
KW-0863--Zinc-finger
--
Interpro

IPR028725--CHD4
IPR012957--CHD_C2
IPR012958--CHD_N
IPR000953--Chromo/shadow_dom
IPR023780--Chromo_domain
IPR016197--Chromodomain-like
IPR002464--DNA/RNA_helicase_DEAH_CS
IPR009462--DUF1086
IPR009463--DUF1087
IPR014001--Helicase_ATP-bd
IPR001650--Helicase_C
IPR027417--P-loop_NTPase
IPR000330--SNF2_N
IPR019786--Zinc_finger_PHD-type_CS
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD
PROSITE

PS00598--CHROMO_1
PS50013--CHROMO_2
PS00690--DEAH_ATP_HELICASE
PS51192--HELICASE_ATP_BIND_1
PS51194--HELICASE_CTER
PS01359--ZF_PHD_1
PS50016--ZF_PHD_2
Pfam

PF08074--CHDCT2
PF08073--CHDNT
PF00385--Chromo
PF06461--DUF1086
PF06465--DUF1087
PF00271--Helicase_C
PF00628--PHD
PF00176--SNF2_N
Gene Ontology

GO:0005813--C:centrosome
GO:0005737--C:cytoplasm
GO:0016020--C:membrane
GO:0000790--C:nuclear chromatin
GO:0005654--C:nucleoplasm
GO:0005634--C:nucleus
GO:0016581--C:NuRD complex
GO:0043234--C:protein complex
GO:0032993--C:protein-DNA complex
GO:0005524--F:ATP binding
GO:0004003--F:ATP-dependent DNA helicase activity
GO:0003677--F:DNA binding
GO:0004407--F:histone deacetylase activity
GO:0001103--F:RNA polymerase II repressing transcription factor binding
GO:0008270--F:zinc ion binding
GO:0043044--P:ATP-dependent chromatin remodeling
GO:0032508--P:DNA duplex unwinding
GO:0016575--P:histone deacetylation
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:1901796--P:regulation of signal transduction by p53 class mediator
GO:0006357--P:regulation of transcription from RNA polymerase II promoter
GO:0051225--P:spindle assembly
GO:0072553--P:terminal button organization
GO:0006351--P:transcription, DNA-templated
Orthology
WERAM ID Ensembl Protein ID Species Identity E-value Score
WERAM-Aim-0162 ENSAMEP00000015022.1 Ailuropoda melanoleuca 98 0.0 3001
WERAM-Chs-0125 ENSCSAP00000006661.1 Chlorocebus sabaeus 100 0.0 2992
WERAM-Mup-0195 ENSMPUP00000016754.1 Mustela putorius furo 99 0.0 2988
WERAM-Mam-0174 ENSMMUP00000024592.2 Macaca mulatta 100 0.0 2988
WERAM-Fec-0075 ENSFCAP00000006385.3 Felis catus 99 0.0 2988
WERAM-Eqc-0182 ENSECAP00000019928.1 Equus caballus 99 0.0 2987
WERAM-Caf-0156 ENSCAFP00000022067.4 Canis familiaris 99 0.0 2984
WERAM-Sus-0008 ENSSSCP00000000743.2 Sus scrofa 99 0.0 2974
WERAM-Otg-0102 ENSOGAP00000008965.2 Otolemur garnettii 98 0.0 2968
WERAM-Myl-0158 ENSMLUP00000013056.2 Myotis lucifugus 99 0.0 2968
WERAM-Paa-0209 ENSPANP00000002367.1 Papio anubis 97 0.0 2967
WERAM-Dan-0007 ENSDNOP00000000870.3 Dasypus novemcinctus 99 0.0 2958
WERAM-Orc-0077 ENSOCUP00000020108.1 Oryctolagus cuniculus 95 0.0 2955
WERAM-Nol-0041 ENSNLEP00000005322.2 Nomascus leucogenys 100 0.0 2954
WERAM-Ict-0076 ENSSTOP00000006839.2 Ictidomys tridecemlineatus 99 0.0 2953
WERAM-Bot-0134 ENSBTAP00000019612.5 Bos taurus 99 0.0 2949
WERAM-Cap-0103 ENSCPOP00000007645.2 Cavia porcellus 98 0.0 2930
WERAM-Mum-0216 ENSMUSP00000060054.8 Mus musculus 98 0.0 2921
WERAM-Ran-0118 ENSRNOP00000052823.4 Rattus norvegicus 97 0.0 2920
WERAM-Ova-0075 ENSOARP00000007963.1 Ovis aries 99 0.0 2910
WERAM-Poa-0040 ENSPPYP00000004777.1 Pongo abelii 98 0.0 2907
WERAM-Ptv-0138 ENSPVAP00000011854.1 Pteropus vampyrus 97 0.0 2902
WERAM-Loa-0181 ENSLAFP00000017802.2 Loxodonta africana 96 0.0 2826
WERAM-Meg-0141 ENSMGAP00000014906.2 Meleagris gallopavo 91 0.0 2797
WERAM-Gaga-0128 ENSGALP00000023294.4 Gallus gallus 91 0.0 2786
WERAM-Tag-0164 ENSTGUP00000013727.1 Taeniopygia guttata 89 0.0 2779
WERAM-Anc-0062 ENSACAP00000006236.3 Anolis carolinensis 89 0.0 2771
WERAM-Anp-0127 ENSAPLP00000014113.1 Anas platyrhynchos 88 0.0 2714
WERAM-Caj-0091 ENSCJAP00000015091.2 Callithrix jacchus 93 0.0 2661
WERAM-Tut-0182 ENSTTRP00000015268.1 Tursiops truncatus 96 0.0 2638
WERAM-Mod-0169 ENSMODP00000022561.3 Monodelphis domestica 95 0.0 2623
WERAM-Pat-0038 ENSPTRP00000039322.3 Pan troglodytes 100 0.0 2485
WERAM-Tub-0084 ENSTBEP00000009893.1 Tupaia belangeri 96 0.0 2383
WERAM-Pes-0148 ENSPSIP00000017808.1 Pelodiscus sinensis 90 0.0 2329
WERAM-Fia-0067 ENSFALP00000004982.1 Ficedula albicollis 92 0.0 2319
WERAM-Asm-0087 ENSAMXP00000009172.1 Astyanax mexicanus 71 0.0 2295
WERAM-Sah-0167 ENSSHAP00000017758.1 Sarcophilus harrisii 93 0.0 2225
WERAM-Xim-0182 ENSXMAP00000014720.1 Xiphophorus maculatus 73 0.0 2147
WERAM-Tar-0001 ENSTRUP00000000282.1 Takifugu rubripes 81 0.0 2111
WERAM-Leo-0071 ENSLOCP00000009062.1 Lepisosteus oculatus 82 0.0 2106
WERAM-Pof-0104 ENSPFOP00000009594.2 Poecilia formosa 83 0.0 2104
WERAM-Orn-0079 ENSONIP00000008816.1 Oreochromis niloticus 81 0.0 2103
WERAM-Tas-0061 ENSTSYP00000005557.1 Tarsius syrichta 87 0.0 2027
WERAM-Gaa-0200 ENSGACP00000024737.1 Gasterosteus aculeatus 76 0.0 1977
WERAM-Dar-0151 ENSDARP00000014790.7 Danio rerio 86 0.0 1973
WERAM-Mae-0139 ENSMEUP00000013963.1 Macropus eugenii 94 0.0 1971
WERAM-Orla-0061 ENSORLP00000007931.1 Oryzias latipes 85 0.0 1966
WERAM-Lac-0045 ENSLACP00000006723.1 Latimeria chalumnae 81 0.0 1942
WERAM-Ten-0096 ENSTNIP00000006980.1 Tetraodon nigroviridis 85 0.0 1918
WERAM-Dio-0013 ENSDORP00000001733.1 Dipodomys ordii 96 0.0 1915
WERAM-Gog-0151 ENSGGOP00000013179.2 Gorilla gorilla 75 0.0 1863
WERAM-Ocp-0036 ENSOPRP00000003260.1 Ochotona princeps 97 0.0 1848
WERAM-Xet-0022 ENSXETP00000006377.3 Xenopus tropicalis 76 0.0 1746
WERAM-Prc-0006 ENSPCAP00000000704.1 Procavia capensis 74 0.0 1650
WERAM-Ect-0124 ENSETEP00000014412.1 Echinops telfairi 75 0.0 1604
WERAM-Gam-0169 ENSGMOP00000016904.1 Gadus morhua 85 0.0 1593
WERAM-Ere-0132 ENSEEUP00000013928.1 Erinaceus europaeus 72 0.0 1587
WERAM-Mim-0160 ENSMICP00000016268.1 Microcebus murinus 73 0.0 1466
WERAM-Chh-0003 ENSCHOP00000000249.1 Choloepus hoffmanni 90 0.0 1447
WERAM-Drm-0093 FBpp0074688 Drosophila melanogaster 62 0.0 1410
WERAM-Ora-0020 ENSOANP00000002890.2 Ornithorhynchus anatinus 64 0.0 1359
WERAM-Cis-0034 ENSCSAVP00000007438.1 Ciona savignyi 60 0.0 1333
WERAM-Cae-0002 T14G8.1 Caenorhabditis elegans 58 0.0 1303
WERAM-Soa-0123 ENSSARP00000011752.1 Sorex araneus 89 0.0 801
WERAM-Sem-0045 EFJ18933 Selaginella moellendorffii 43 0.0 741
WERAM-Glm-0057 GLYMA06G06720.1 Glycine max 44 0.0 736
WERAM-Met-0079 AES73562 Medicago truncatula 43 0.0 734
WERAM-Prp-0013 EMJ26664 Prunus persica 43 0.0 724
WERAM-Php-0082 PP1S33_329V6.1 Physcomitrella patens 42 0.0 722
WERAM-Bro-0158 Bo8g099350.1 Brassica oleracea 42 0.0 717
WERAM-Brr-0040 Bra007814.1-P Brassica rapa 42 0.0 716
WERAM-Viv-0017 VIT_04s0008g05880.t01 Vitis vinifera 42 0.0 713
WERAM-Amt-0083 ERN02848 Amborella trichopoda 41 0.0 712
WERAM-Art-0045 AT2G25170.1 Arabidopsis thaliana 41 0.0 712
WERAM-Sol-0080 Solyc06g065730.2.1 Solanum lycopersicum 43 0.0 710
WERAM-Arl-0023 fgenesh1_pg.C_scaffold_4000458 Arabidopsis lyrata 41 0.0 698
WERAM-Sei-0019 Si005700m Setaria italica 42 0.0 697
WERAM-Orbr-0069 OB06G14970.1 Oryza brachyantha 41 0.0 691
WERAM-Mua-0075 GSMUA_Achr4P21270_001 Musa acuminata 41 0.0 683
WERAM-Orb-0059 OBART06G05400.1 Oryza barthii 41 0.0 679
WERAM-Orni-0056 ONIVA06G06230.1 Oryza nivara 41 0.0 679
WERAM-Aet-0096 EMT22305 Aegilops tauschii 41 0.0 674
WERAM-Org-0057 ORGLA06G0049200.1 Oryza glaberrima 41 0.0 674
WERAM-Brd-0024 BRADI1G47367.1 Brachypodium distachyon 42 0.0 671
WERAM-Orr-0060 ORUFI06G05540.1 Oryza rufipogon 43 0.0 656
WERAM-Orgl-0059 OGLUM06G05590.1 Oryza glumaepatula 43 0.0 655
WERAM-Tru-0086 TRIUR3_31334-P1 Triticum urartu 42 0.0 655
WERAM-Ori-0068 BGIOSGA021779-PA Oryza indica 43 0.0 654
WERAM-Tra-0315 Traes_7BS_4FE42A949.1 Triticum aestivum 46 2e-176 617
WERAM-Orm-0057 OMERI06G06420.1 Oryza meridionalis 41 5e-169 593
WERAM-Hov-0079 MLOC_61346.1 Hordeum vulgare 44 9e-163 573
WERAM-Vip-0109 ENSVPAP00000010051.1 Vicugna pacos 88 1e-161 569
WERAM-Thc-0019 EOX96881 Theobroma cacao 41 4e-148 524
WERAM-Orl-0055 KN539084.1_FGP003 Oryza longistaminata 37 5e-147 520
WERAM-Pot-0009 POPTR_0001s26030.1 Populus trichocarpa 44 3e-146 518
WERAM-Sob-0039 Sb02g041910.1 Sorghum bicolor 42 9e-146 516
Created Date 25-Jun-2016