WERAM Information

Tag Content
WERAM ID WERAM-Art-0098
Ensembl Protein ID AT4G12620.1
Uniprot Accession Q9SU24; ORC1B_ARATH
Genbank Protein ID NP_192999.1
Protein Name Origin of replication complex subunit 1B
Genbank Nucleotide ID NM_117332.2
Gene Name ORC1B;UNE13;At4g12620;T1P17.210
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
AT4G12620 AT4G12620.1 AT4G12620.1
Details
Type Family Domain Substrates AA References (PMIDs)
Me_Reader PHD PHD-type H3K4me3 K 19171893
Status Reviewed
Classification
Type Family E-value Score Start End
Me_Reader PHD 9.50e-12 45.7 168 213
Organism Arabidopsis thaliana
NCBI Taxa ID 3702
Functional Description
(View)		 Essential protein required for ovules fertilization (PubMed:15634699, PubMed:19171893). Component of the origin recognition complex (ORC) that binds origins of replication. It has a role in both chromosomal replication and mating type transcriptional silencing. Binds to the ARS consensus sequence (ACS) of origins of replication (By similarity). H3K4me3 effector that regulates positively the transcription of a subset of genes (PubMed:19171893).
Domain Profile
  Me_Reader PHD
      PHD.txt   3 iClvCgkddegekemvqCdeCddwfHlkCvklplsslpegkswyCpsCk 51 
                   C++C k+d++  +m++Cd C   fHlkC+k+pl+++peg +w+C+ C+
  AT4G12620.1 168 DCQICFKSDTN--IMIECDDCLGGFHLKCLKPPLKEVPEG-DWICQFCE 213
                  5****888888..7**************************.*******7 PP
Protein Sequence
(Fasta)		MASTPRAKTF KSPTKTPSNI YRKSYLSPSS TSHTPQTPET HTPLRRSARH VSRKIDLGND 60
PIDAPGNDPI EGMNLIRKRE RAPRKPTTDV VPSKSKKTET PKKKKKIDSF TPVSPIRSET 120
IKKTKKKKRV YYNKVEFDET EFEIGDDVYV KRREDSNSDE EEDPEIEDCQ ICFKSDTNIM 180
IECDDCLGGF HLKCLKPPLK EVPEGDWICQ FCEVKKSGQS QTLDLPKPPE GKKLARTMRE 240
KLLSGDLWAA RIDKLWKEVD DGVYWIRARW YMIPEETVSG RQPHNLKREL YLTNDFADIE 300
MECILRHCSV KCPKEFSKAS NDGDDVFLCE YEYDVHWRSF KRLAELADGD SDSDQEWNGR 360
KEEEVDDSDE EMELDDEVLK SKRGGLTSAR GGANSRKGRF FGVEKVGMKL IPEHVRCHKQ 420
SELEKAKATL LLATRPKSLP CRSKEMEEIT SFIKGSISDD QCLGRCMYIH GVPGTGKTIS 480
VLSVMKNLKA EVEEGSVSPY CFVEINGLKL ASPENIYSVI YEALSGHRVG WKKALQCLNE 540
RFAEGKRIGK EDEKPCILLI DELDLLVTRN QSVLYNILDW PTKPNSKLVV LGIANTMDLP 600
EKLLPRISSR MGIQRLCFGP YNHTQLQEII STRLNGIDAF EKTAIEFASR KVAAISGDAR 660
RALEICRRAA EVADHRLNTN KSAKNQLVIM ADVEAAIQEM FQAPHIQVMK SVSKLSKIFL 720
TAMVHELYKT GMAETTFDRV ATTVSSICLT NGEAFPGWDI LLKIGCDLGE CRIILCEPGE 780
KHRLQKLQLN FPSDDVAFAL KDNKDLPWLA NYL 813
Nucleotide Sequence
(Fasta)		ATGGCTTCAA CTCCAAGAGC AAAAACCTTC AAATCCCCAA CCAAAACTCC GTCTAACATC 60
TATCGCAAAT CGTATCTATC TCCATCTTCA ACCTCACACA CTCCTCAAAC CCCAGAAACT 120
CACACTCCTC TCCGTAGATC TGCTCGTCAT GTTTCTCGTA AAATCGATCT GGGAAATGAC 180
CCAATTGATG CTCCAGGAAA TGACCCAATC GAAGGAATGA ATCTAATTCG AAAACGAGAA 240
CGTGCCCCCA GAAAACCAAC CACTGATGTC GTTCCATCGA AGTCGAAGAA AACAGAAACT 300
CCGAAGAAGA AGAAGAAGAT AGATTCCTTC ACTCCTGTTT CACCAATTAG ATCTGAGACG 360
ATTAAGAAGA CGAAGAAGAA GAAGAGAGTT TATTACAATA AAGTCGAATT CGACGAAACC 420
GAATTCGAAA TCGGTGATGA TGTTTACGTT AAGAGAAGAG AAGATTCGAA TTCAGATGAA 480
GAAGAAGATC CAGAAATTGA AGATTGTCAG ATTTGTTTCA AATCAGATAC TAACATAATG 540
ATTGAGTGTG ATGATTGTTT AGGTGGATTT CATTTGAAAT GCTTGAAACC GCCATTGAAG 600
GAAGTTCCTG AAGGTGATTG GATCTGTCAA TTCTGTGAGG TTAAAAAGTC TGGTCAAAGT 660
CAAACACTTG ACCTTCCTAA GCCACCGGAA GGGAAGAAGT TAGCGAGAAC TATGAGGGAG 720
AAGCTACTTT CCGGTGATCT ATGGGCTGCT CGAATCGACA AGTTATGGAA AGAAGTTGAT 780
GATGGTGTGT ATTGGATTCG TGCTCGTTGG TATATGATAC CTGAAGAGAC CGTTTCGGGG 840
CGTCAACCGC ATAATCTGAA ACGAGAGCTT TATTTGACGA ATGATTTTGC TGATATAGAG 900
ATGGAATGTA TTCTTAGGCA TTGTTCTGTC AAGTGTCCTA AGGAGTTTTC GAAAGCTAGT 960
AATGATGGTG ATGATGTGTT CTTGTGTGAG TATGAGTATG ATGTTCATTG GCGTAGCTTT 1020
AAGCGTTTGG CTGAATTGGC TGATGGAGAT TCTGATAGTG ATCAAGAGTG GAATGGTAGG 1080
AAGGAGGAGG AGGTTGATGA TAGTGATGAA GAGATGGAGC TTGATGATGA AGTTTTGAAG 1140
AGTAAGCGAG GAGGTTTGAC TAGTGCAAGA GGAGGTGCGA ACTCTCGTAA AGGGAGATTC 1200
TTTGGGGTTG AGAAGGTGGG GATGAAGCTG ATTCCTGAAC ATGTGAGATG TCATAAGCAG 1260
AGTGAGTTAG AAAAGGCGAA AGCTACTTTG TTGTTGGCTA CACGTCCTAA GTCTCTTCCT 1320
TGTAGAAGCA AAGAAATGGA AGAGATCACT TCGTTTATAA AAGGTTCAAT CTCGGATGAT 1380
CAGTGTTTAG GAAGATGTAT GTATATTCAT GGTGTTCCCG GGACTGGGAA GACTATTAGT 1440
GTGTTATCGG TTATGAAGAA TCTGAAGGCT GAGGTTGAAG AGGGAAGCGT AAGCCCTTAT 1500
TGCTTTGTGG AGATCAATGG TCTCAAATTG GCTTCACCTG AGAACATTTA CAGTGTAATC 1560
TATGAAGCAT TGAGTGGTCA TCGAGTCGGT TGGAAGAAAG CTCTACAGTG TCTAAATGAG 1620
AGGTTTGCAG AAGGAAAAAG GATTGGTAAA GAGGATGAGA AGCCTTGCAT ACTTCTCATC 1680
GACGAACTTG ATCTTCTAGT AACTAGAAAC CAGTCTGTTT TATACAACAT TCTTGATTGG 1740
CCTACCAAGC CTAACTCCAA ATTAGTTGTG TTGGGAATAG CAAACACTAT GGATCTTCCA 1800
GAGAAGCTGC TTCCTCGGAT TTCTAGCCGA ATGGGTATAC AGAGACTATG TTTCGGTCCT 1860
TATAACCACA CTCAGCTACA AGAAATCATT TCTACAAGGT TGAATGGAAT AGATGCTTTC 1920
GAGAAGACAG CTATTGAATT TGCTTCGAGA AAAGTAGCTG CGATTTCAGG AGATGCAAGA 1980
CGTGCGCTTG AGATATGCAG GCGTGCTGCA GAAGTAGCGG ATCACCGTCT AAATACTAAC 2040
AAATCCGCAA AGAATCAGCT GGTGATTATG GCAGATGTTG AAGCAGCTAT CCAAGAGATG 2100
TTTCAGGCAC CTCATATTCA AGTGATGAAG AGCGTGTCAA AACTGAGTAA AATCTTCTTG 2160
ACGGCTATGG TTCATGAGCT TTACAAAACA GGAATGGCAG AGACAACATT TGACCGAGTG 2220
GCAACGACAG TATCGTCTAT CTGCTTAACC AATGGAGAAG CTTTTCCAGG TTGGGACATT 2280
CTTCTTAAAA TCGGTTGCGA TCTTGGTGAA TGTAGGATCA TTCTCTGTGA ACCTGGAGAG 2340
AAGCATAGAT TGCAGAAGCT GCAGCTGAAT TTTCCAAGTG ATGATGTTGC TTTTGCATTG 2400
AAAGACAATA AGGATCTTCC ATGGCTGGCC AATTACTTGT GAGTTTTTTT TCTGTTTATT 2460
GAATCACTCA ACTTTAAATT TAAAGACTAG TTTGATTCAT ATGATTATCT GGACTTTGTA 2520
TCTGTTTTTA AAATGTGTTA TGTATCATTT GTTTGTGAAA TCACATACAC AGTTGTATTT 2580
TTTTCTCTAG AGAATATTTA TTCTTACG 2609
Sequence Source Ensembl
Keyword

KW-0002--3D-structure
KW-0010--Activator
KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0235--DNA replication
KW-0238--DNA-binding
KW-0479--Metal-binding
KW-0547--Nucleotide-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0804--Transcription
KW-0805--Transcription regulation
KW-0862--Zinc
KW-0863--Zinc-finger
--
Interpro

IPR003593--AAA+_ATPase
IPR003959--ATPase_AAA_core
IPR001025--BAH_dom
IPR027417--P-loop_NTPase
IPR019786--Zinc_finger_PHD-type_CS
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD
PROSITE

PS51038--BAH
PS01359--ZF_PHD_1
PS50016--ZF_PHD_2
Pfam

PF00004--AAA
PF01426--BAH
PF00628--PHD
Gene Ontology

GO:0005634--C:nucleus
GO:0000808--C:origin recognition complex
GO:0005524--F:ATP binding
GO:0003682--F:chromatin binding
GO:0010385--F:double-stranded methylated DNA binding
GO:0008270--F:zinc ion binding
GO:0006260--P:DNA replication
GO:0009567--P:double fertilization forming a zygote and endosperm
GO:0006355--P:regulation of transcription, DNA-templated
GO:0006351--P:transcription, DNA-templated
Orthology
WERAM ID Ensembl Protein ID Species Identity E-value Score
WERAM-Arl-0096 fgenesh2_kg.6__ 3199__ AT4G12620.1 Arabidopsis lyrata 94 0.0 1387
WERAM-Brr-0148 Bra029471.1-P Brassica rapa 79 0.0 1192
WERAM-Bro-0178 Bo9g078420.1 Brassica oleracea 79 0.0 1189
WERAM-Thc-0110 EOY32655 Theobroma cacao 72 0.0 1005
WERAM-Pot-0103 POPTR_0009s05910.1 Populus trichocarpa 70 0.0 988
WERAM-Prp-0096 EMJ14761 Prunus persica 71 0.0 969
WERAM-Glm-0175 GLYMA13G41490.1 Glycine max 71 0.0 962
WERAM-Met-0185 KEH21251 Medicago truncatula 71 0.0 961
WERAM-Sol-0041 Solyc03g006420.2.1 Solanum lycopersicum 71 0.0 949
WERAM-Viv-0033 VIT_06s0004g02050.t01 Vitis vinifera 71 0.0 943
WERAM-Amt-0031 ERN11779 Amborella trichopoda 67 0.0 908
WERAM-Mua-0132 GSMUA_Achr8P31340_001 Musa acuminata 63 0.0 900
WERAM-Zem-0094 GRMZM2G168249_P01 Zea mays 63 0.0 896
WERAM-Sob-0130 Sb10g005910.1 Sorghum bicolor 63 0.0 873
WERAM-Sei-0023 Si005876m Setaria italica 64 0.0 867
WERAM-Brd-0023 BRADI1G47050.1 Brachypodium distachyon 62 0.0 863
WERAM-Org-0058 ORGLA06G0052100.1 Oryza glaberrima 63 0.0 863
WERAM-Orgl-0060 OGLUM06G05860.1 Oryza glumaepatula 64 0.0 860
WERAM-Orm-0058 OMERI06G06700.1 Oryza meridionalis 64 0.0 859
WERAM-Lep-0062 LPERR06G05260.1 Leersia perrieri 63 0.0 857
WERAM-Orbr-0070 OB06G15250.1 Oryza brachyantha 64 0.0 845
WERAM-Orr-0061 ORUFI06G05830.1 Oryza rufipogon 64 0.0 834
WERAM-Orp-0057 OPUNC06G05470.1 Oryza punctata 62 0.0 832
WERAM-Orl-0031 KN538791.1_FGP002 Oryza longistaminata 62 0.0 828
WERAM-Orb-0060 OBART06G05680.1 Oryza barthii 63 0.0 826
WERAM-Sot-0106 PGSC0003DMT400033353 Solanum tuberosum 70 0.0 775
WERAM-Hov-0026 MLOC_18813.1 Hordeum vulgare 61 0.0 719
WERAM-Orni-0060 ONIVA06G15290.1 Oryza nivara 59 0.0 699
WERAM-Sem-0120 EFJ23163 Selaginella moellendorffii 52 0.0 670
WERAM-Php-0132 PP1S90_96V6.1 Physcomitrella patens 46 0.0 639
WERAM-Osl-0008 ABO95923 Ostreococcus lucimarinus 35 2e-109 394
WERAM-Ova-0046 ENSOARP00000005671.1 Ovis aries 42 1e-83 308
WERAM-Eqc-0055 ENSECAP00000007647.1 Equus caballus 41 1e-77 289
WERAM-Mam-0129 ENSMMUP00000018823.2 Macaca mulatta 42 1e-76 285
WERAM-Orc-0009 ENSOCUP00000000831.2 Oryctolagus cuniculus 42 2e-76 284
WERAM-Gog-0040 ENSGGOP00000003862.2 Gorilla gorilla 41 3e-76 284
WERAM-Hos-0043 ENSP00000360621.1 Homo sapiens 41 5e-76 283
WERAM-Caf-0044 ENSCAFP00000005581.3 Canis familiaris 41 6e-76 283
WERAM-Ict-0135 ENSSTOP00000013960.2 Ictidomys tridecemlineatus 41 8e-76 282
WERAM-Pat-0006 ENSPTRP00000001270.2 Pan troglodytes 41 9e-76 282
WERAM-Caj-0225 ENSCJAP00000040193.2 Callithrix jacchus 41 2e-75 281
WERAM-Aim-0101 ENSAMEP00000009770.1 Ailuropoda melanoleuca 42 2e-75 281
WERAM-Paa-0148 ENSPANP00000000718.1 Papio anubis 41 2e-75 281
WERAM-Mup-0074 ENSMPUP00000006849.1 Mustela putorius furo 41 3e-75 280
WERAM-Chs-0014 ENSCSAP00000016740.1 Chlorocebus sabaeus 41 3e-75 280
WERAM-Poa-0010 ENSPPYP00000001568.1 Pongo abelii 41 1e-74 279
WERAM-Ran-0055 ENSRNOP00000012492.5 Rattus norvegicus 41 1e-74 278
WERAM-Bot-0032 ENSBTAP00000003523.5 Bos taurus 41 1e-74 278
WERAM-Cap-0056 ENSCPOP00000004564.2 Cavia porcellus 41 2e-74 278
WERAM-Mum-0092 ENSMUSP00000099805.3 Mus musculus 40 2e-74 278
WERAM-Loa-0046 ENSLAFP00000003139.3 Loxodonta africana 42 2e-74 278
WERAM-Sus-0025 ENSSSCP00000004177.1 Sus scrofa 41 4e-74 277
WERAM-Fec-0027 ENSFCAP00000002316.3 Felis catus 40 1e-73 275
WERAM-Tub-0063 ENSTBEP00000007929.1 Tupaia belangeri 40 6e-72 270
WERAM-Tut-0183 ENSTTRP00000015290.1 Tursiops truncatus 43 1e-68 259
WERAM-Chr-0014 EDP07857 Chlamydomonas reinhardtii 33 5e-53 206
WERAM-Ptv-0102 ENSPVAP00000009238.1 Pteropus vampyrus 36 1e-20 99.4
WERAM-Cae-0003 ZK783.4 Caenorhabditis elegans 49 6e-10 63.9
WERAM-Orla-0127 ENSORLP00000015292.1 Oryzias latipes 46 2e-09 62.4
WERAM-Fia-0048 ENSFALP00000003379.1 Ficedula albicollis 40 1e-08 59.7
WERAM-Tag-0148 ENSTGUP00000012613.1 Taeniopygia guttata 40 1e-08 59.7
WERAM-Gaga-0116 ENSGALP00000020513.1 Gallus gallus 43 2e-08 59.3
WERAM-Meg-0125 ENSMGAP00000013670.2 Meleagris gallopavo 43 2e-08 59.3
WERAM-Leo-0054 ENSLOCP00000007276.1 Lepisosteus oculatus 40 2e-08 58.9
WERAM-Dar-0123 ENSDARP00000101556.2 Danio rerio 49 2e-08 58.9
WERAM-Prc-0102 ENSPCAP00000009508.1 Procavia capensis 41 2e-08 58.5
WERAM-Orn-0105 ENSONIP00000011234.1 Oreochromis niloticus 48 2e-08 58.5
WERAM-Pof-0142 ENSPFOP00000011949.1 Poecilia formosa 47 3e-08 58.5
WERAM-Lac-0014 ENSLACP00000002295.1 Latimeria chalumnae 47 3e-08 58.5
WERAM-Asm-0016 ENSAMXP00000002046.1 Astyanax mexicanus 39 3e-08 58.2
WERAM-Drm-0059 FBpp0078401 Drosophila melanogaster 47 4e-08 58.2
WERAM-Gaa-0019 ENSGACP00000002833.1 Gasterosteus aculeatus 43 4e-08 57.8
WERAM-Dio-0052 ENSDORP00000005019.1 Dipodomys ordii 47 4e-08 57.8
WERAM-Ect-0112 ENSETEP00000012551.1 Echinops telfairi 47 5e-08 57.8
WERAM-Myl-0085 ENSMLUP00000006798.2 Myotis lucifugus 47 5e-08 57.8
WERAM-Tas-0059 ENSTSYP00000005370.1 Tarsius syrichta 47 5e-08 57.8
WERAM-Mim-0001 ENSMICP00000000022.1 Microcebus murinus 47 5e-08 57.8
WERAM-Dan-0056 ENSDNOP00000017553.2 Dasypus novemcinctus 47 5e-08 57.8
WERAM-Vip-0080 ENSVPAP00000007479.1 Vicugna pacos 49 5e-08 57.8
WERAM-Mod-0005 ENSMODP00000000887.5 Monodelphis domestica 47 5e-08 57.8
WERAM-Gam-0003 ENSGMOP00000000211.1 Gadus morhua 43 5e-08 57.4
WERAM-Anp-0093 ENSAPLP00000010721.1 Anas platyrhynchos 47 5e-08 57.4
WERAM-Otg-0164 ENSOGAP00000013816.2 Otolemur garnettii 47 5e-08 57.4
WERAM-Ora-0060 ENSOANP00000009404.2 Ornithorhynchus anatinus 47 6e-08 57.4
WERAM-Anc-0090 ENSACAP00000008638.3 Anolis carolinensis 48 6e-08 57.4
WERAM-Pes-0123 ENSPSIP00000014751.1 Pelodiscus sinensis 45 6e-08 57.4
WERAM-Sah-0096 ENSSHAP00000011021.1 Sarcophilus harrisii 47 6e-08 57.4
WERAM-Soa-0082 ENSSARP00000007754.1 Sorex araneus 47 6e-08 57.4
WERAM-Tar-0172 ENSTRUP00000036180.1 Takifugu rubripes 45 8e-08 57.0
WERAM-Ten-0198 ENSTNIP00000019882.1 Tetraodon nigroviridis 45 9e-08 56.6
WERAM-Pug-0032 EFP89803 Puccinia graminis 47 1e-07 56.6
WERAM-Xim-0193 ENSXMAP00000015562.1 Xiphophorus maculatus 45 1e-07 56.6
WERAM-Nol-0010 ENSNLEP00000001331.1 Nomascus leucogenys 40 1e-07 56.2
WERAM-Mae-0106 ENSMEUP00000010312.1 Macropus eugenii 43 1e-07 56.2
WERAM-Xet-0052 ENSXETP00000016514.3 Xenopus tropicalis 40 2e-07 55.8
WERAM-Spr-0023 CBQ72974 Sporisorium reilianum 28 2e-07 55.5
WERAM-Ocp-0127 ENSOPRP00000013509.1 Ochotona princeps 43 2e-07 55.5
Created Date 25-Jun-2016