WERAM Information


Tag Content
WERAM ID WERAM-Sac-0042
Ensembl Protein ID YOR064C
Uniprot Accession Q08465; YNG1_YEAST; D6W2C7; O00025
Genbank Protein ID NP_014707.1
Protein Name Protein YNG1
Genbank Nucleotide ID NM_001183483.1
Gene Name Yng1;YOR064C;YOR29-15
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
YOR064C YOR064C YOR064C
Details
Type Family Domain Substrates AA References (PMIDs)
Me_Reader PHD PHD-type H3K4me3 K 17157260
Status Reviewed
Classification
Type Family E-value Score Start End
Me_Reader PHD 6.70e-11 40.7 156 201
Organism Saccharomyces cerevisiae
NCBI Taxa ID 559292
Functional Description
(View)
Histone-binding component of the NuA3 histone acetyltransferase complex, that acetylates Lys-14 of histone H3. Recruitment of NuA3 to nucleosomes requires methylated histone H3. In conjunction with the FACT complex, NuA3 may be involved in transcriptional regulation. YNG1 is required for the HAT activity of NuA3 but not for its integrity. Mediates the interaction of SAS3 with nucleosomes.
Domain Profile
  Me_Reader PHD

  PHD.txt   2 tiClvCgkddegekemvqCde..Cd.dwfHlkCvklplsslpegkswyCpsC 50 
+C+ C+++++g mv Cd+ C+ +wfH+ Cv+l+ ++p+g +wyC +
YOR064C 156 VYCF-CRNVSYGP--MVACDNpaCPfEWFHYGCVGLK--QAPKG-KWYCSKD 201
69*8.******94..**********************..*****.****863 PP

Protein Sequence
(Fasta)
MEHLANENSD SDIRYSFLST LDHLPCELIR SLRLMQTIDL FKNEEDEPGM ERACRDLLLV 60
ATYINDLVDD QIHFLKQHKK ELEIQKSVTK NFNSSLENIK SKLTLEEPGA YKEPKLLLKI 120
NLKKAKSRER KESITSPTIG INQGDVTEGN NNQEEVYCFC RNVSYGPMVA CDNPACPFEW 180
FHYGCVGLKQ APKGKWYCSK DCKEIANQRS KSKRQKRRK 219
Nucleotide Sequence
(Fasta)
ATGGAACATC TCGCCAACGA AAACTCGGAT TCGGATATCA GGTACAGTTT CCTTAGCACT 60
TTGGATCATT TACCATGTGA ACTAATAAGA TCTCTTCGAC TGATGCAAAC AATCGACTTA 120
TTCAAGAATG AAGAGGATGA GCCTGGTATG GAAAGGGCCT GTAGGGATCT GTTGCTGGTA 180
GCGACTTATA TTAATGATCT GGTCGATGAT CAGATTCATT TCTTAAAGCA GCATAAGAAG 240
GAACTAGAGA TACAGAAGTC AGTGACAAAA AATTTCAACT CTTCGCTAGA GAATATCAAG 300
TCGAAGTTGA CGTTAGAAGA ACCAGGAGCA TATAAGGAGC CAAAACTGCT TTTAAAGATT 360
AACTTGAAAA AGGCTAAATC GAGGGAAAGA AAAGAGAGCA TAACTAGCCC CACAATTGGG 420
ATTAACCAGG GTGATGTAAC AGAGGGTAAT AATAATCAAG AGGAGGTTTA TTGTTTCTGT 480
AGGAATGTAT CTTATGGGCC AATGGTGGCT TGTGATAATC CGGCTTGTCC CTTCGAGTGG 540
TTCCATTATG GTTGCGTAGG CCTGAAACAA GCTCCCAAGG GCAAATGGTA TTGTAGCAAA 600
GATTGTAAGG AAATAGCAAA CCAGAGGTCC AAGTCAAAAC GGCAAAAAAG AAGAAAGTAA 660
661
Sequence Source Ensembl
Keyword

KW-0002--3D-structure
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0804--Transcription
KW-0805--Transcription regulation
KW-0862--Zinc
KW-0863--Zinc-finger
--

Interpro

IPR028651--ING_fam
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR013083--Znf_RING/FYVE/PHD

PROSITE
Pfam
Gene Ontology

GO:0033100--C:NuA3 histone acetyltransferase complex
GO:1990467--C:NuA3a histone acetyltransferase complex
GO:0035064--F:methylated histone binding
GO:0008270--F:zinc ion binding
GO:0016568--P:chromatin modification
GO:0016573--P:histone acetylation
GO:0032968--P:positive regulation of transcription elongation from RNA polymerase II promoter
GO:0006351--P:transcription, DNA-templated

Orthology
WERAM ID Ensembl Protein ID Species Identity E-value Score
WERAM-Cag-0027 CAG62192 Candida glabrata 36 1e-33 140
WERAM-Kll-0031 CAG98531 Kluyveromyces lactis 38 2e-28 122
WERAM-Asg-0013 AAS52127 Ashbya gossypii 33 2e-25 112
WERAM-Glm-0258 GLYMA20G19970.1 Glycine max 76 4e-19 92.0
WERAM-Thc-0053 EOY05425 Theobroma cacao 69 5e-19 91.7
WERAM-Drm-0038 FBpp0074385 Drosophila melanogaster 59 6e-19 91.3
WERAM-Met-0017 KEH41192 Medicago truncatula 76 7e-19 90.9
WERAM-Sot-0036 PGSC0003DMT400030294 Solanum tuberosum 73 1e-18 90.5
WERAM-Sol-0119 Solyc09g091190.2.1 Solanum lycopersicum 73 1e-18 90.5
WERAM-Pot-0039 POPTR_0003s17260.1 Populus trichocarpa 67 2e-18 89.7
WERAM-Orn-0086 ENSONIP00000009520.1 Oreochromis niloticus 67 4e-18 88.6
WERAM-Pes-0054 ENSPSIP00000007361.1 Pelodiscus sinensis 67 5e-18 88.2
WERAM-Sah-0147 ENSSHAP00000015324.1 Sarcophilus harrisii 67 5e-18 88.2
WERAM-Dar-0072 ENSDARP00000031200.5 Danio rerio 73 6e-18 87.8
WERAM-Leo-0165 ENSLOCP00000019441.1 Lepisosteus oculatus 67 6e-18 87.8
WERAM-Mae-0124 ENSMEUP00000012568.1 Macropus eugenii 67 7e-18 87.8
WERAM-Tar-0017 ENSTRUP00000003694.1 Takifugu rubripes 73 8e-18 87.8
WERAM-Asm-0105 ENSAMXP00000010482.1 Astyanax mexicanus 73 9e-18 87.4
WERAM-Bot-0150 ENSBTAP00000021725.5 Bos taurus 73 9e-18 87.4
WERAM-Mup-0077 ENSMPUP00000006997.1 Mustela putorius furo 73 1e-17 87.4
WERAM-Ora-0058 ENSOANP00000008990.3 Ornithorhynchus anatinus 67 1e-17 87.4
WERAM-Ect-0116 ENSETEP00000013115.1 Echinops telfairi 67 1e-17 87.4
WERAM-Cis-0005 ENSCSAVP00000000824.1 Ciona savignyi 73 1e-17 87.4
WERAM-Anc-0074 ENSACAP00000006929.2 Anolis carolinensis 73 1e-17 87.4
WERAM-Loa-0213 ENSLAFP00000019667.1 Loxodonta africana 73 1e-17 87.4
WERAM-Chh-0044 ENSCHOP00000005027.1 Choloepus hoffmanni 73 1e-17 87.4
WERAM-Ova-0192 ENSOARP00000019466.1 Ovis aries 73 1e-17 87.0
WERAM-Chs-0132 ENSCSAP00000006990.1 Chlorocebus sabaeus 73 1e-17 87.0
WERAM-Paa-0124 ENSPANP00000004010.1 Papio anubis 73 1e-17 87.0
WERAM-Hov-0088 MLOC_66032.4 Hordeum vulgare 73 1e-17 87.0
WERAM-Fec-0200 ENSFCAP00000020713.1 Felis catus 73 1e-17 87.0
WERAM-Soa-0122 ENSSARP00000011714.1 Sorex araneus 73 1e-17 87.0
WERAM-Ptv-0107 ENSPVAP00000009534.1 Pteropus vampyrus 73 1e-17 87.0
WERAM-Otg-0055 ENSOGAP00000003761.2 Otolemur garnettii 73 1e-17 87.0
WERAM-Dan-0010 ENSDNOP00000001153.3 Dasypus novemcinctus 73 1e-17 87.0
WERAM-Poa-0165 ENSPPYP00000020124.2 Pongo abelii 73 1e-17 87.0
WERAM-Pat-0164 ENSPTRP00000033606.4 Pan troglodytes 73 1e-17 87.0
WERAM-Nol-0127 ENSNLEP00000014397.1 Nomascus leucogenys 73 1e-17 87.0
WERAM-Hos-0029 ENSP00000320566.5 Homo sapiens 73 1e-17 87.0
WERAM-Caf-0038 ENSCAFP00000005192.3 Canis familiaris 73 1e-17 87.0
WERAM-Aim-0073 ENSAMEP00000006322.1 Ailuropoda melanoleuca 73 1e-17 87.0
WERAM-Ten-0032 ENSTNIP00000006039.1 Tetraodon nigroviridis 73 1e-17 87.0
WERAM-Tag-0065 ENSTGUP00000004796.1 Taeniopygia guttata 73 1e-17 87.0
WERAM-Myl-0177 ENSMLUP00000014873.2 Myotis lucifugus 73 1e-17 87.0
WERAM-Sus-0124 ENSSSCP00000017603.2 Sus scrofa 73 1e-17 87.0
WERAM-Ict-0046 ENSSTOP00000003622.2 Ictidomys tridecemlineatus 73 1e-17 87.0
WERAM-Eqc-0045 ENSECAP00000006448.1 Equus caballus 73 1e-17 87.0
WERAM-Anp-0009 ENSAPLP00000001673.1 Anas platyrhynchos 73 1e-17 87.0
WERAM-Orc-0015 ENSOCUP00000001622.3 Oryctolagus cuniculus 73 1e-17 87.0
WERAM-Tra-0133 Traes_4AL_78F1233CC.2 Triticum aestivum 73 1e-17 87.0
WERAM-Caj-0180 ENSCJAP00000031565.1 Callithrix jacchus 73 1e-17 87.0
WERAM-Cii-0019 ENSCINP00000007229.3 Ciona intestinalis 71 1e-17 87.0
WERAM-Tut-0185 ENSTTRP00000015382.1 Tursiops truncatus 73 1e-17 87.0
WERAM-Cap-0197 ENSCPOP00000018334.1 Cavia porcellus 73 1e-17 87.0
WERAM-Prp-0084 EMJ28765 Prunus persica 65 2e-17 86.7
WERAM-Gog-0044 ENSGGOP00000004268.2 Gorilla gorilla 70 2e-17 86.7
WERAM-Fia-0124 ENSFALP00000010408.1 Ficedula albicollis 73 2e-17 86.3
WERAM-Meg-0093 ENSMGAP00000008949.1 Meleagris gallopavo 73 2e-17 86.3
WERAM-Gaga-0094 ENSGALP00000014665.4 Gallus gallus 73 2e-17 86.3
WERAM-Amt-0044 ERN15806 Amborella trichopoda 70 2e-17 86.3
WERAM-Lac-0111 ENSLACP00000013747.2 Latimeria chalumnae 71 2e-17 86.3
WERAM-Map-0022 MAPG_06745T0 Magnaporthe poae 59 2e-17 86.3
WERAM-Tas-0001 ENSTSYP00000000124.1 Tarsius syrichta 70 2e-17 85.9
WERAM-Tru-0022 TRIUR3_10173-P1 Triticum urartu 73 3e-17 85.9
WERAM-Gam-0190 ENSGMOP00000018296.1 Gadus morhua 71 3e-17 85.9
WERAM-Mum-0100 ENSMUSP00000031680.3 Mus musculus 71 3e-17 85.9
WERAM-Xim-0108 ENSXMAP00000009576.1 Xiphophorus maculatus 71 3e-17 85.9
WERAM-Ran-0034 ENSRNOP00000007476.4 Rattus norvegicus 71 3e-17 85.5
WERAM-Pof-0248 ENSPFOP00000029114.1 Poecilia formosa 71 3e-17 85.5
WERAM-Gaa-0006 ENSGACP00000000841.2 Gasterosteus aculeatus 71 3e-17 85.5
WERAM-Art-0077 AT3G24010.1 Arabidopsis thaliana 71 4e-17 85.5
WERAM-Viv-0027 VIT_05s0051g00350.t01 Vitis vinifera 69 4e-17 85.1
WERAM-Kop-0013 CAY68936 Komagataella pastoris 53 5e-17 85.1
WERAM-Ocp-0149 ENSOPRP00000015445.1 Ochotona princeps 70 5e-17 85.1
WERAM-Sob-0014 Sb01g047350.1 Sorghum bicolor 71 5e-17 84.7
WERAM-Xet-0056 ENSXETP00000018004.3 Xenopus tropicalis 26 9e-17 84.0
WERAM-Arl-0064 fgenesh2_kg.3__ 2635__ AT3G24010.1 Arabidopsis lyrata 71 1e-16 84.0
WERAM-Bro-0124 Bo7g036450.1 Brassica oleracea 63 1e-16 83.6
WERAM-Brr-0075 Bra015016.1-P Brassica rapa 63 1e-16 83.6
WERAM-Pem-0004 ENSPMAP00000000234.1 Petromyzon marinus 72 2e-16 83.2
WERAM-Brd-0037 BRADI1G75507.1 Brachypodium distachyon 71 2e-16 83.2
WERAM-Mod-0036 ENSMODP00000005573.2 Monodelphis domestica 64 3e-16 82.4
WERAM-Lab-0045 EDR11353 Laccaria bicolor 55 3e-16 82.4
WERAM-Prc-0118 ENSPCAP00000010407.1 Procavia capensis 73 3e-16 82.4
WERAM-Trr-0023 EGR50784 Trichoderma reesei 49 3e-16 82.4
WERAM-Orbr-0038 OB03G13430.1 Oryza brachyantha 71 3e-16 82.4
WERAM-Tum-0009 CAZ80653 Tuber melanosporum 69 3e-16 82.0
WERAM-Orla-0198 ENSORLP00000022617.2 Oryzias latipes 64 3e-16 82.0
WERAM-Lep-0035 LPERR03G03140.1 Leersia perrieri 69 4e-16 82.0
WERAM-Zem-0100 GRMZM2G178072_P01 Zea mays 71 4e-16 81.6
WERAM-Php-0066 PP1S277_88V6.1 Physcomitrella patens 62 5e-16 81.6
WERAM-Sei-0135 Si037216m Setaria italica 69 6e-16 81.3
WERAM-Gag-0006 GGTG_01534T0 Gaeumannomyces graminis 71 6e-16 81.3
WERAM-Trv-0014 EHK16380 Trichoderma virens 67 7e-16 81.3
WERAM-Mam-0207 ENSMMUP00000019814.2 Macaca mulatta 64 7e-16 81.3
WERAM-Chg-0006 EAQ93274 Chaetomium globosum 65 8e-16 80.9
WERAM-Mao-0004 MGG_01632T0 Magnaporthe oryzae 63 9e-16 80.9
WERAM-Fuo-0001 FOXG_00026P0 Fusarium oxysporum 67 1e-15 80.9
WERAM-Lem-0003 CBY01795 Leptosphaeria maculans 53 1e-15 80.5
WERAM-Scp-0025 SPBC1709.11c.1:pep Schizosaccharomyces pombe 45 1e-15 80.1
WERAM-Dio-0008 ENSDORP00000001052.1 Dipodomys ordii 46 2e-15 80.1
WERAM-Orp-0029 OPUNC03G03150.1 Oryza punctata 67 2e-15 80.1
WERAM-Usm-0007 UM01188P0 Ustilago maydis 58 2e-15 79.7
WERAM-Spr-0004 CBQ70596 Sporisorium reilianum 58 2e-15 79.7
WERAM-Asfu-0003 CADAFUAP00001152 Aspergillus fumigatus 66 2e-15 79.7
WERAM-Ors-0028 OS03T0143600-01 Oryza sativa 67 2e-15 79.7
WERAM-Orni-0030 ONIVA03G03130.1 Oryza nivara 67 2e-15 79.7
WERAM-Ori-0037 BGIOSGA011837-PA Oryza indica 67 2e-15 79.7
WERAM-Org-0031 ORGLA03G0031600.1 Oryza glaberrima 67 2e-15 79.7
WERAM-Ved-0013 EGY21584 Verticillium dahliae 69 2e-15 79.3
WERAM-Sem-0058 EFJ35540 Selaginella moellendorffii 58 2e-15 79.3
WERAM-Mua-0030 GSMUA_Achr1P03410_001 Musa acuminata 67 2e-15 79.3
WERAM-Orm-0033 OMERI03G03370.1 Oryza meridionalis 67 2e-15 79.3
WERAM-Asc-0027 CADACLAP00006087 Aspergillus clavatus 66 2e-15 79.3
WERAM-Asn-0035 CADANIAP00009484 Aspergillus nidulans 67 3e-15 79.3
WERAM-Nec-0014 EFNCRP00000002588 Neurospora crassa 68 3e-15 79.3
WERAM-Mim-0014 ENSMICP00000001205.1 Microcebus murinus 62 3e-15 79.0
WERAM-Coi-0022 EAS33451 Coccidioides immitis 60 3e-15 79.0
WERAM-Vip-0056 ENSVPAP00000005332.1 Vicugna pacos 62 4e-15 79.0
Created Date 25-Jun-2016