WERAM Information

Tag Content
WERAM ID WERAM-Sac-0006
Ensembl Protein ID YDL070W
Uniprot Accession Q07442; BDF2_YEAST; D6VRS8
Genbank Protein ID NP_010213.1
Protein Name Bromodomain-containing factor 2
Genbank Nucleotide ID NM_001180129.1
Gene Name BDF2;YDL070W
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
YDL070W YDL070W YDL070W
Details
Type Family Domain Substrates AA References (PMIDs)
Ac_Reader Bromodomain Bromodomain K 25254151
Status Reviewed
Classification
Type Family E-value Score Start End
Ac_Reader Bromodomain 1.20e-42 142.3 152 408
Organism Saccharomyces cerevisiae
NCBI Taxa ID 559292
Functional Description
(View)		 Transcription factor involved in the expression of a broad class of genes including snRNAs. Required for sporulation and DNA-damage repair. Prevents the spreading of SIR silencing at telomeres and protects histone H4, but not H3, from deacetylation (By similarity).
Domain Profile
  Ac_Reader Bromodomain
  BROMO.txt   3 hevsepFrepvdpq.leipdYydiikePmdLstikerleegnYsspeefvkDvrlifnNakaynenkssv 71 
                 +++ pF +pvdp  l+ip+Y++ +++PmdLs+i+ +l+ + Y s+e++  D++ +++N+ ++n+++ss+
    YDL070W 152 LKDARPFLKPVDPIaLNIPHYFNYVQTPMDLSLIETKLQGNVYHSVEQVTSDFKTMVDNCLNFNGPESSI 221
                5799**************************************************************9986 PP
  BROMO.txt   6 sepFrepvdpq.leipdYydiikePmdLstikerleegnYsspeefvkDvrlifnNakaynenkssv 71 
                  pF +pvdp  l++p+Y+d++k+PmdL ti ++l++ +Y+++++fv+D++l+f N+ ++n+++++v
    YDL070W 342 NFPFLQPVDPIaLNLPNYFDVVKNPMDLGTISNNLMNWKYKTIDQFVDDLNLVFYNCFQFNPEGNEV 408
                569***********************************************************99987 PP
Protein Sequence
(Fasta)		MSRTNMDTRH AHSALLAAPQ SATANSRSSN SSSESSSNKN NINVGVGDDS GNVSAVSIDD 60
GPHFRDIFHY GHEENYKLAS SGITNLNSSS HAHQTLSPIS ISNASTPESF PEHPLGLERE 120
TEPALEAEME AEELPPHQSK YLLSSIKATK RLKDARPFLK PVDPIALNIP HYFNYVQTPM 180
DLSLIETKLQ GNVYHSVEQV TSDFKTMVDN CLNFNGPESS ISSMAKRIQK YFEKKLSAMP 240
PRVLPASALK KTSRNRKKNE DMDSPLVIRR SVSTTNDNIG ESGNREGVSG GRPKRTIHPP 300
KSKDLFDIYE NSKPKSKTLQ KKFRTCLKIL KVLMSKKNSD INFPFLQPVD PIALNLPNYF 360
DVVKNPMDLG TISNNLMNWK YKTIDQFVDD LNLVFYNCFQ FNPEGNEVHS MGKKLKELFN 420
FHWLENQDIL NEIETDSDLE EDNYSSSYSS DDEYDDEDIN ENDITNPAIQ YLEQKLKKME 480
VELQQLKRQE LSKLSKERKR KHLGKTLLRR KAMKHSVDDL KKSITDKINE LSDLEMNGMI 540
RIIKNSLPAD EILTSNEDEI EIDLDILDEA TIARIYERYF EKKNNNNSKR KLSGNYSTAP 600
TNKKKKTLKF LEKDEIINNN NYSDSEEDSS DSSDSDSD 638
Nucleotide Sequence
(Fasta)		ATGTCTCGTA CTAACATGGA TACAAGACAC GCACATTCTG CTTTACTGGC AGCACCACAG 60
AGTGCTACTG CAAATAGCAG GAGCAGCAAC AGCAGCAGCG AGAGTAGTAG TAACAAAAAC 120
AATATCAATG TCGGCGTCGG TGACGATAGC GGTAATGTCA GCGCGGTAAG TATCGACGAT 180
GGACCCCACT TCAGGGATAT CTTCCACTAT GGACACGAGG AAAATTACAA ACTTGCGAGC 240
AGCGGTATCA CTAACCTGAA TTCTTCATCC CACGCCCACC AAACTTTGTC TCCCATTTCC 300
ATTAGTAATG CATCCACTCC GGAAAGTTTT CCCGAGCACC CTTTGGGCCT AGAACGGGAA 360
ACAGAGCCGG CGTTGGAAGC TGAAATGGAA GCGGAGGAAC TACCACCACA CCAAAGTAAA 420
TACCTTTTAA GCTCCATTAA GGCGACCAAA CGATTAAAAG ATGCTAGACC GTTTCTGAAG 480
CCGGTTGATC CTATTGCTTT GAACATCCCG CATTATTTCA ACTACGTTCA AACCCCAATG 540
GATTTGTCTT TAATTGAAAC AAAATTGCAG GGCAACGTGT ATCATTCAGT AGAGCAAGTC 600
ACATCGGACT TCAAAACAAT GGTGGATAAT TGTTTAAACT TTAATGGTCC AGAATCTTCA 660
ATCTCTTCGA TGGCTAAAAG GATTCAAAAG TATTTTGAAA AAAAGTTATC TGCAATGCCA 720
CCAAGAGTTT TACCCGCTTC TGCCTTGAAG AAAACAAGCA GAAACCGGAA AAAAAATGAG 780
GATATGGATT CCCCACTTGT CATTAGACGT TCAGTTAGTA CCACCAATGA CAATATTGGG 840
GAAAGCGGAA ATAGAGAAGG CGTCAGTGGT GGTAGACCCA AAAGAACAAT TCATCCACCC 900
AAATCAAAAG ATTTGTTTGA TATATATGAA AACTCCAAAC CAAAATCAAA GACTTTACAA 960
AAAAAATTCA GGACTTGTCT GAAAATACTA AAGGTTTTGA TGAGTAAAAA AAATTCGGAT 1020
ATAAATTTTC CCTTTTTACA ACCTGTTGAT CCGATTGCTT TGAATCTACC AAATTACTTT 1080
GATGTCGTGA AGAATCCTAT GGATTTGGGT ACAATATCAA ATAATTTAAT GAACTGGAAG 1140
TACAAAACAA TTGATCAATT TGTCGACGAC CTCAACCTTG TCTTTTATAA TTGTTTCCAA 1200
TTCAATCCAG AAGGCAATGA AGTCCATTCA ATGGGCAAAA AACTAAAAGA GCTTTTCAAT 1260
TTTCATTGGT TAGAGAACCA GGATATTTTG AATGAAATTG AAACGGATTC AGATCTTGAA 1320
GAGGATAACT ATTCTTCTTC ATATTCATCT GATGATGAAT ATGATGATGA AGACATAAAT 1380
GAAAACGATA TAACTAATCC GGCTATTCAA TATTTGGAAC AAAAACTGAA GAAAATGGAG 1440
GTTGAATTGC AACAATTGAA AAGACAAGAG TTAAGTAAAT TATCGAAGGA AAGGAAGAGG 1500
AAGCATCTAG GTAAAACGCT TTTGCGTAGG AAGGCAATGA AGCATTCAGT TGACGATTTA 1560
AAGAAATCTA TTACTGATAA AATCAATGAA TTAAGTGATT TAGAAATGAA TGGGATGATT 1620
CGTATCATTA AAAATTCATT ACCCGCAGAT GAAATACTAA CTTCCAATGA AGATGAAATT 1680
GAAATTGATT TGGATATTTT AGATGAAGCG ACTATTGCAA GAATTTATGA GAGATATTTT 1740
GAGAAAAAAA ATAACAACAA TAGCAAAAGA AAACTAAGTG GCAACTACTC GACTGCGCCA 1800
ACTAACAAGA AAAAGAAAAC CTTGAAATTT TTGGAAAAGG ATGAAATCAT AAATAATAAT 1860
AATTATTCCG ATTCTGAAGA AGACAGTAGT GATAGTAGCG ACAGTGACAG TGATTAA 1918
Sequence Source Ensembl
Keyword

KW-0103--Bromodomain
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0227--DNA damage
KW-0234--DNA repair
KW-0539--Nucleus
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0677--Repeat
KW-0749--Sporulation
KW-0804--Transcription
KW-0805--Transcription regulation
--
Interpro

IPR001487--Bromodomain
IPR018359--Bromodomain_CS
IPR027353--NET_dom
PROSITE

PS00633--BROMODOMAIN_1
PS50014--BROMODOMAIN_2
PS51525--NET
Pfam

PF17035--BET
PF00439--Bromodomain
Gene Ontology

GO:0005737--C:cytoplasm
GO:0005634--C:nucleus
GO:0001047--F:core promoter binding
GO:0042393--F:histone binding
GO:0070577--F:lysine-acetylated histone binding
GO:0001094--F:TFIID-class transcription factor binding
GO:0006281--P:DNA repair
GO:0031452--P:negative regulation of heterochromatin assembly
GO:0006355--P:regulation of transcription, DNA-templated
GO:0030435--P:sporulation resulting in formation of a cellular spore
GO:0006351--P:transcription, DNA-templated
Orthology
WERAM ID Ensembl Protein ID Species Identity E-value Score
WERAM-Cag-0007 CAG58193 Candida glabrata 46 1e-101 367
WERAM-Kll-0009 CAH02064 Kluyveromyces lactis 45 3e-96 350
WERAM-Asg-0020 AAS52752 Ashbya gossypii 44 1e-92 338
WERAM-Kop-0005 CAY68055 Komagataella pastoris 41 2e-79 294
WERAM-Caa-0023 KGT67266 Candida albicans 38 4e-74 276
WERAM-Yal-0020 CAG79786 Yarrowia lipolytica 38 4e-71 266
WERAM-Coi-0008 EAS36106 Coccidioides immitis 36 7e-56 216
WERAM-Pytr-0019 EDU48226 Pyrenophora triticirepentis 38 2e-54 211
WERAM-Asni-0013 CADANGAP00004232 Aspergillus niger 36 2e-53 207
WERAM-Tum-0025 CAZ84417 Tuber melanosporum 37 4e-53 207
WERAM-Asn-0033 CADANIAP00008646 Aspergillus nidulans 37 2e-52 204
WERAM-Pyt-0004 EFQ95588 Pyrenophora teres 37 2e-52 204
WERAM-Phn-0031 SNOT_15588 Phaeosphaeria nodorum 34 3e-52 204
WERAM-Aso-0014 CADAORAP00001680 Aspergillus oryzae 37 4e-52 203
WERAM-Asf-0005 CADAFLAP00002036 Aspergillus flavus 37 6e-52 202
WERAM-Scj-0016 EEB07414 Schizosaccharomyces japonicus 29 2e-51 201
WERAM-Ast-0035 CADATEAP00009448 Aspergillus terreus 37 6e-51 199
WERAM-Asc-0023 CADACLAP00004832 Aspergillus clavatus 31 2e-50 197
WERAM-Lab-0004 EDR16082 Laccaria bicolor 36 4e-50 196
WERAM-Lem-0016 CBX93493 Leptosphaeria maculans 36 2e-49 194
WERAM-Asfu-0033 CADAFUAP00007736 Aspergillus fumigatus 34 7e-49 192
WERAM-Scp-0043 SPCC1450.02.1:pep Schizosaccharomyces pombe 37 8e-48 189
WERAM-Leo-0036 ENSLOCP00000005834.1 Lepisosteus oculatus 32 6e-40 163
WERAM-Crn-0041 AAW46194 Cryptococcus neoformans 34 1e-39 162
WERAM-Orc-0168 ENSOCUP00000015006.3 Oryctolagus cuniculus 32 3e-39 160
WERAM-Ora-0005 ENSOANP00000000712.2 Ornithorhynchus anatinus 32 5e-38 156
WERAM-Gam-0156 ENSGMOP00000015464.1 Gadus morhua 31 3e-37 154
WERAM-Myl-0068 ENSMLUP00000005696.2 Myotis lucifugus 30 7e-37 152
WERAM-Ran-0018 ENSRNOP00000058256.2 Rattus norvegicus 29 8e-37 152
WERAM-Mum-0096 ENSMUSP00000031215.8 Mus musculus 30 8e-37 152
WERAM-Tub-0073 ENSTBEP00000009277.1 Tupaia belangeri 30 1e-36 152
WERAM-Eqc-0123 ENSECAP00000013753.1 Equus caballus 29 1e-36 152
WERAM-Fec-0165 ENSFCAP00000017154.1 Felis catus 29 1e-36 152
WERAM-Mup-0046 ENSMPUP00000004278.1 Mustela putorius furo 29 2e-36 151
WERAM-Miv-0006 MVLG_00349T0 Microbotryum violaceum 28 6e-36 149
WERAM-Ict-0035 ENSSTOP00000002736.2 Ictidomys tridecemlineatus 31 9e-36 149
WERAM-Orn-0225 ENSONIP00000024235.1 Oreochromis niloticus 30 9e-36 149
WERAM-Aim-0010 ENSAMEP00000000596.1 Ailuropoda melanoleuca 30 1e-35 149
WERAM-Tar-0033 ENSTRUP00000007860.1 Takifugu rubripes 29 5e-35 147
WERAM-Gaa-0134 ENSGACP00000017249.1 Gasterosteus aculeatus 29 2e-34 144
WERAM-Gag-0010 GGTG_02275T0 Gaeumannomyces graminis 32 4e-34 144
WERAM-Orla-0126 ENSORLP00000015257.1 Oryzias latipes 31 2e-33 141
WERAM-Spr-0030 CBQ73835 Sporisorium reilianum 28 3e-33 140
WERAM-Dar-0221 ENSDARP00000130622.1 Danio rerio 29 3e-33 140
WERAM-Xim-0143 ENSXMAP00000011561.1 Xiphophorus maculatus 28 4e-33 140
WERAM-Cae-0070 Y119C1B.8a Caenorhabditis elegans 28 3e-32 137
WERAM-Chs-0015 ENSCSAP00000016562.1 Chlorocebus sabaeus 28 6e-32 136
WERAM-Usm-0023 UM03437P0 Ustilago maydis 28 6e-32 136
WERAM-Zyt-0010 Mycgr3P15552 Zymoseptoria tritici 30 3e-31 134
WERAM-Vip-0103 ENSVPAP00000009601.1 Vicugna pacos 29 3e-31 134
WERAM-Anp-0129 ENSAPLP00000014301.1 Anas platyrhynchos 27 4e-31 134
WERAM-Poa-0009 ENSPPYP00000001343.1 Pongo abelii 27 6e-31 133
WERAM-Ved-0014 EGY22392 Verticillium dahliae 29 8e-31 132
WERAM-Map-0018 MAPG_06130T0 Magnaporthe poae 32 2e-30 131
WERAM-Mim-0130 ENSMICP00000013048.1 Microcebus murinus 28 4e-30 130
WERAM-Caj-0188 ENSCJAP00000032249.2 Callithrix jacchus 27 1e-29 129
WERAM-Chg-0043 EAQ84216 Chaetomium globosum 31 2e-29 128
WERAM-Ptv-0051 ENSPVAP00000005427.1 Pteropus vampyrus 27 7e-29 126
WERAM-Pes-0007 ENSPSIP00000002650.1 Pelodiscus sinensis 27 2e-27 121
WERAM-Mao-0025 MGG_08925T0 Magnaporthe oryzae 30 8e-26 116
WERAM-Pof-0041 ENSPFOP00000003134.2 Poecilia formosa 38 4e-25 114
WERAM-Cii-0085 ENSCINP00000034825.1 Ciona intestinalis 32 2e-24 111
WERAM-Ten-0212 ENSTNIP00000021345.1 Tetraodon nigroviridis 40 3e-24 111
WERAM-Trv-0039 EHK18374 Trichoderma virens 29 4e-24 110
WERAM-Asm-0150 ENSAMXP00000014454.1 Astyanax mexicanus 36 9e-24 109
WERAM-Lac-0143 ENSLACP00000016410.1 Latimeria chalumnae 41 9e-24 109
WERAM-Xet-0123 ENSXETP00000042370.3 Xenopus tropicalis 36 1e-23 109
WERAM-Gaga-0001 ENSGALP00000000211.4 Gallus gallus 39 2e-23 108
WERAM-Chh-0047 ENSCHOP00000005329.1 Choloepus hoffmanni 39 3e-23 107
WERAM-Anc-0036 ENSACAP00000004148.2 Anolis carolinensis 36 4e-23 107
WERAM-Soa-0062 ENSSARP00000006154.1 Sorex araneus 38 5e-23 107
WERAM-Loa-0152 ENSLAFP00000013518.3 Loxodonta africana 38 9e-23 105
WERAM-Cap-0011 ENSCPOP00000001274.2 Cavia porcellus 32 1e-22 105
WERAM-Prc-0094 ENSPCAP00000008495.1 Procavia capensis 38 1e-22 105
WERAM-Sah-0133 ENSSHAP00000014254.1 Sarcophilus harrisii 43 1e-22 105
WERAM-Caf-0209 ENSCAFP00000029909.3 Canis familiaris 29 1e-22 105
WERAM-Ere-0086 ENSEEUP00000008250.1 Erinaceus europaeus 39 1e-22 105
WERAM-Tut-0048 ENSTTRP00000004025.1 Tursiops truncatus 38 1e-22 105
WERAM-Ova-0082 ENSOARP00000008629.1 Ovis aries 38 1e-22 105
WERAM-Tas-0039 ENSTSYP00000004094.1 Tarsius syrichta 38 1e-22 105
WERAM-Fia-0022 ENSFALP00000001679.1 Ficedula albicollis 40 1e-22 105
WERAM-Bot-0108 ENSBTAP00000014704.5 Bos taurus 38 1e-22 105
WERAM-Sus-0016 ENSSSCP00000001595.1 Sus scrofa 38 1e-22 105
WERAM-Sei-0094 Si026157m Setaria italica 36 1e-22 105
WERAM-Ocp-0078 ENSOPRP00000006813.1 Ochotona princeps 38 1e-22 105
WERAM-Otg-0077 ENSOGAP00000005790.2 Otolemur garnettii 38 1e-22 105
WERAM-Dan-0048 ENSDNOP00000004798.3 Dasypus novemcinctus 38 1e-22 105
WERAM-Pat-0149 ENSPTRP00000030782.4 Pan troglodytes 38 2e-22 105
WERAM-Paa-0136 ENSPANP00000012397.1 Papio anubis 38 2e-22 105
WERAM-Mod-0128 ENSMODP00000017862.3 Monodelphis domestica 38 2e-22 105
WERAM-Hos-0255 ENSP00000372588.2 Homo sapiens 38 2e-22 105
WERAM-Gog-0065 ENSGGOP00000005721.2 Gorilla gorilla 38 2e-22 105
WERAM-Mam-0211 ENSMMUP00000030455.2 Macaca mulatta 38 2e-22 105
WERAM-Trr-0004 EGR44176 Trichoderma reesei 28 2e-22 105
WERAM-Nol-0068 ENSNLEP00000008263.2 Nomascus leucogenys 38 2e-22 104
WERAM-Arl-0014 Al_scaffold_0008_162 Arabidopsis lyrata 42 3e-22 104
WERAM-Mae-0045 ENSMEUP00000004128.1 Macropus eugenii 39 4e-22 103
WERAM-Dio-0124 ENSDORP00000011896.1 Dipodomys ordii 39 4e-22 103
WERAM-Tag-0083 ENSTGUP00000005921.1 Taeniopygia guttata 39 4e-22 103
WERAM-Meg-0076 ENSMGAP00000000015.2 Meleagris gallopavo 39 5e-22 103
WERAM-Drm-0012 FBpp0071074 Drosophila melanogaster 41 6e-22 103
WERAM-Glm-0166 GLYMA13G29430.3 Glycine max 43 8e-22 102
WERAM-Ect-0114 ENSETEP00000012589.1 Echinops telfairi 37 2e-21 101
WERAM-Thc-0078 EOY27851 Theobroma cacao 43 2e-21 101
WERAM-Lep-0111 LPERR11G14070.1 Leersia perrieri 43 3e-21 100
WERAM-Zem-0095 GRMZM2G169688_P01 Zea mays 41 4e-21 100
WERAM-Orbr-0085 OB07G21530.1 Oryza brachyantha 43 4e-21 100
WERAM-Amt-0007 ERN06807 Amborella trichopoda 37 7e-21 99.8
Created Date 25-Jun-2016