| Tag |
Content |
| WERAM ID |
WERAM-Scp-0034 |
| Ensembl Protein ID |
SPBC428.08c.1:pep |
| Uniprot Accession |
O60016; CLR4_SCHPO; O74565
|
| Genbank Protein ID |
NP_595186.1
|
| Protein Name |
Histone-lysine N-methyltransferase, H3 lysine-9 specific |
| Genbank Nucleotide ID |
NM_001021094.2
|
| Gene Name |
Clr4;kmt1;SPBC428.08c |
| Ensembl Information |
|
| Details |
| Type |
Family |
Domain |
Substrates |
AA |
References (PMIDs) |
| HMT |
SUV39 |
SET |
H3K9 |
K |
20236312; 15958184
|
| Me_Reader |
Chromodomain |
Chromo |
H3K9me3 |
K |
26496625
|
|
| Status |
Reviewed |
| Classification |
| Type |
Family |
E-value |
Score |
Start |
End |
| HMT |
SUV39 |
3.20e-36 |
122.7 |
119 |
451 |
| Me_Reader |
Chromodomain |
2.30e-21 |
73.7 |
8 |
68 |
|
| Organism |
Schizosaccharomyces pombe |
| NCBI Taxa ID |
284812 |
Functional Description
(View)Functional Description
Histone methyltransferase. Catalytic component of the rik1-associated E3 ubiquitin ligase complex that shows ubiquitin ligase activity and is required for histone H3K9 methylation. H3K9me represents a specific tag for epigenetic transcriptional repression by recruiting swi6/HP1 to methylated histones which leads to transcriptional silencing within centromeric heterochromatin, telomeric regions and at the silent mating-type loci. |
Histone methyltransferase. Catalytic component of the rik1-associated E3 ubiquitin ligase complex that shows ubiquitin ligase activity and is required for histone H3K9 methylation. H3K9me represents a specific tag for epigenetic transcriptional repression by recruiting swi6/HP1 to methylated histones which leads to transcriptional silencing within centromeric heterochromatin, telomeric regions and at the silent mating-type loci.
|
| Domain Profile |
HMT SUV39
SUV39.txt 72 vplssdssntrqekdkeeseyi 93
+ ++s ++++ +++++++i
SPBC428.08c.1:pep 119 QTTKRQSRKQSTALTTNDTSII 140
1122222222222233333333 PP
SUV39.txt 2 rLqvfktenkGwGvrclddiakgsFvciyaGeiltddeaekegl...eegdeyladldsk 58
+L++fkt++kGwGvr+l+ ++g+F++ y Ge++t++ea k++ ++g +yl+dld+
SPBC428.08c.1:pep 329 PLEIFKTKEKGWGVRSLRFAPAGTFITCYLGEVITSAEAAKRDKnydDDGITYLFDLDMF 388
69****************************************764556666799999976 PP
SUV39.txt 87 keeseyiidakkegnvgrflnHscspNlfvqnvfvdthdlrfprvafFaskrikagtELtwdY 149
++ sey++da+++g+v+rf+nHscspN+++ + + ++ ++++ +afFa k+i++ +ELt+dY
SPBC428.08c.1:pep 389 DDASEYTVDAQNYGDVSRFFNHSCSPNIAIYSAVRNHGFRTIYDLAFFAIKDIQPLEELTFDY 451
5789*********************************************************** PP
Me_Reader Chromodomain
Chromodomain.txt 1 Feverivdkkelrkgeve.YlVrWkGynksddtWepeenLl.ckelleefekkkekkkkqg 59
+everivd+k r+g v+ Y++rW++y++++dtWep enL+ c+++l+e++++k++ k ++
SPBC428.08c.1:pep 8 YEVERIVDEKLDRNGAVKlYRIRWLNYSSRSDTWEPPENLSgCSAVLAEWKRRKRRLKGSN 68
89*****************************************************998775 PP
|
Protein Sequence
(Fasta) | MSPKQEEYEV ERIVDEKLDR NGAVKLYRIR WLNYSSRSDT WEPPENLSGC SAVLAEWKRR 60
KRRLKGSNSD SDSPHHASNP HPNSRQKHQH QTSKSVPRSQ RFSRELNVKK ENKKVFSSQT 120
TKRQSRKQST ALTTNDTSII LDDSLHTNSK KLGKTRNEVK EESQKRELVS NSIKEATSPK 180
TSSILTKPRN PSKLDSYTHL SFYEKRELFR KKLREIEGPE VTLVNEVDDE PCPSLDFQFI 240
SQYRLTQGVI PPDPNFQSGC NCSSLGGCDL NNPSRCECLD DLDEPTHFAY DAQGRVRADT 300
GAVIYECNSF CSCSMECPNR VVQRGRTLPL EIFKTKEKGW GVRSLRFAPA GTFITCYLGE 360
VITSAEAAKR DKNYDDDGIT YLFDLDMFDD ASEYTVDAQN YGDVSRFFNH SCSPNIAIYS 420
AVRNHGFRTI YDLAFFAIKD IQPLEELTFD YAGAKDFSPV QSQKSQQNRI SKLRRQCKCG 480
SANCRGWLFG Protein Fasta Sequence
>SPBC428.08c.1:pep|Clr4;kmt1;SPBC428.08c|Schizosaccharomyces pombe
MSPKQEEYEVERIVDEKLDRNGAVKLYRIRWLNYSSRSDTWEPPENLSGCSAVLAEWKRRKRRLKGSNSDSDSPHHASNPHPNSRQKHQHQTSKSVPRSQRFSRELNVKKENKKVFSSQTTKRQSRKQSTALTTNDTSIILDDSLHTNSKKLGKTRNEVKEESQKRELVSNSIKEATSPKTSSILTKPRNPSKLDSYTHLSFYEKRELFRKKLREIEGPEVTLVNEVDDEPCPSLDFQFISQYRLTQGVIPPDPNFQSGCNCSSLGGCDLNNPSRCECLDDLDEPTHFAYDAQGRVRADTGAVIYECNSFCSCSMECPNRVVQRGRTLPLEIFKTKEKGWGVRSLRFAPAGTFITCYLGEVITSAEAAKRDKNYDDDGITYLFDLDMFDDASEYTVDAQNYGDVSRFFNHSCSPNIAIYSAVRNHGFRTIYDLAFFAIKDIQPLEELTFDYAGAKDFSPVQSQKSQQNRISKLRRQCKCGSANCRGWLFG |
Nucleotide Sequence
(Fasta) | GTTGTTAACA CCGTATTTCC TTTACGGGGC GATTCTCCGT TTCTTTAAAT TTTGACTTCT 60
GTAAAGGAGT GCGATTCAAC AACCTGGTCG AAATACAAAC TGTTATAACA TGAATTGGCA 120
TTGCTAGTTT GGATTGTTGT TTGAAAGTTG ATTTGTATAT TATAACTTTA AAATTACTTT 180
GTACTTGATA CCTTTTTCAA ATTTCAGAGC TTCAATTTTG CTCTGAAATT GAACACATCG 240
ACTTTATATA TTTATTGCTC ATTACTAAAA AACATTCAGT TTTATATTCT GAGTTCGCGG 300
TCGTCTATTA TTTTAGTCCT TTAGCAATTG TCATATTAAC ATAAACCCTC TCCTTATTTT 360
ATTTTTTAAA TTCGTTCAGG CATCATTTGG AGGGTTTGCT AAAAATCATC TCACCAAACA 420
AGAGGTTATT AGTTTTGCGA ATGTCGCCTA AACAAGAGGA GTATGAAGTT GAAAGGATTG 480
TGGACGAAAA ATTGGATCGT AATGGAGCTG TCAAACTATA TCGCATTCGA TGGTTGAACT 540
ATTCATCTAG AAGTGATACT TGGGAGCCCC CTGAGAACCT TTCTGGATGT TCTGCCGTTT 600
TAGCAGAATG GAAAAGGCGG AAGAGGAGAC TAAAGGGAAG TAACTCCGAC TCGGATTCAC 660
CGCACCATGC GAGCAATCCA CATCCAAACA GTAGACAAAA GCACCAACAT CAAACTTCAA 720
AGTCAGTGCC TCGTTCTCAA AGATTTTCGC GGGAATTGAA TGTAAAAAAG GAAAATAAAA 780
AGGTTTTTTC TTCTCAAACT ACCAAGAGAC AATCTCGAAA ACAATCCACC GCTCTGACGA 840
CGAATGATAC TAGTATCATT TTAGACGATA GTCTTCATAC AAATTCAAAG AAGCTGGGGA 900
AGACGAGAAA TGAAGTGAAG GAGGAATCTC AAAAAAGAGA ACTAGTTTCC AATTCTATTA 960
AAGAAGCTAC ATCCCCCAAA ACATCTTCAA TTCTCACAAA ACCGCGAAAC CCTTCCAAAC 1020
TTGACTCTTA TACCCATCTA AGTTTTTACG AAAAGAGAGA GCTATTTCGT AAGAAACTGC 1080
GGGAAATTGA AGGACCCGAA GTAACGCTTG TCAATGAAGT TGACGATGAA CCCTGTCCAT 1140
CTTTAGATTT TCAATTCATT AGCCAGTACC GCTTAACACA AGGTGTTATC CCGCCTGATC 1200
CAAATTTTCA ATCTGGATGC AATTGCTCGT CCCTTGGCGG TTGTGACCTT AACAATCCTT 1260
CTCGTTGTGA GTGTTTAGAT GATTTGGATG AGCCAACTCA TTTTGCCTAT GATGCACAGG 1320
GGCGGGTCCG TGCAGATACG GGTGCCGTTA TATATGAATG CAACTCTTTT TGTTCTTGTT 1380
CAATGGAGTG TCCTAATCGC GTTGTTCAAC GTGGTAGAAC TCTTCCGCTT GAAATATTTA 1440
AAACAAAAGA AAAAGGATGG GGTGTACGTT CGCTTCGATT TGCCCCTGCT GGCACGTTTA 1500
TCACTTGCTA TTTAGGAGAA GTCATAACTT CAGCAGAGGC CGCCAAGCGT GACAAAAATT 1560
ATGACGACGA CGGTATTACC TATTTATTTG ATTTAGACAT GTTTGATGAT GCTAGCGAGT 1620
ATACAGTGGA TGCTCAGAAC TATGGAGATG TCTCTCGTTT TTTTAACCAC TCCTGTTCAC 1680
CTAATATAGC TATTTATTCT GCTGTTCGGA ACCATGGATT TCGAACCATT TATGATCTCG 1740
CTTTTTTTGC CATCAAAGAC ATTCAGCCTC TAGAGGAGCT TACATTTGAT TACGCTGGTG 1800
CAAAAGATTT CTCACCTGTT CAATCTCAAA AATCTCAGCA AAATAGAATT TCAAAACTTC 1860
GCCGGCAGTG CAAATGTGGT TCCGCTAATT GTCGTGGCTG GCTTTTCGGT TAAGCTAATT 1920
TATTACTGGT TGACTCCAAT AATTACAATT TGTTTTTCTC CATTACTGTT AAACTGAAAA 1980
AGGTCATTCA TTTTCTAAGC AACGAGATTA TGTATATTAT CTGACCTGTG GGATTTGCCG 2040
AACAATTATC GGTAAAACAT ATCGGTGCTT ATATTTTTTA CACTTGTTGA AAGCATTATA 2100
GTAATTGTTG TAAAGCCTAG CGTTAATGGA AAAACTCTTT TCATCTGCTG CGCACATGTG 2160
AAGTAAAAAG GGCGTTTAAG CGTTAACGGT AATGGACCGT CCTTCAGAAG CTATAGAAGG 2220
AGCTGCTTCT GTTTCGAGCA CCTGGGGCAT CTGATTGTTT TCTCCTTCTG CTGAGGCGAG 2280
GGCATCAGTT GTTTCTTCAG CTGGGTCTTC TTGTGCAGCT GTTCGAGGCG TTGGAGTTGT 2340
TGTAGGAGTT AAGGGAGTTT CCGGTTTTAT TGTGGTTTTT GAGAACTGGG AAATTTCTTT 2400
TAGTCTCCCG TCTTTATCAA ACTTCTTATG CACTTTTTTT TGCACCAAAC CTGAGAGCTT 2460
CTTTGAAAGG TTGGAAGGAA ATATCTCAAA TCCTGCCTTA GCAAATTCAA GGGAAGGATC 2520
TGCCTGTAAA GTTTTAACAC TTTTGGTAGG TTTAGCATAC TTGTGAAGCT TAAAGCCGAA 2580
TACTCTCTTG TTGCCTCCTT TTTTCTTCTT ATGATGCCGA TGATGCTTTT TTCCGGCTTT 2640
CTTAGACGTT CTATCTTCAT TGCTGACAAC ACTCTCTTCA TTAGTAGCTG CAGTGGAAGG 2700
GTCTTGATCG TCTGCAGTAG GGGTCGCAAC ATCGGGAAGT GCTATATCAG GAAGTGCAAT 2760
ATCAGTCTCT TCTATGAAAG CTTGTTCAAC TGATTGGGCT GTACCTTTAA CATCTTCTTC 2820
AATGGCGTCT GCTATTTGAC CGATGGGGGT TCCGTTATCA TTTTGAGTAG AAGCTTGCTC 2880
AACATTTTGA GTTGATGTTG ATTCTTCTGC CGGACCTGTG GCTGGTTTTT CTTCTGATGC 2940
GGGAGCCACT TCTTCCGTAG TAGCAGGAAA ATGTTCTTCA GTGGTGGGAA TTTGGTTAGT 3000
TTCATTCTCA GGAACTTCGA CTGATTGTGC TTCAACAGTA GTATCAACCG GGTCAGCTGA 3060
CGTTTCATTA TCAATGGGAC TAGCCGTATC GTTTTGCGGA GTTTTCCCCT TAATCATGTT 3120
TTGAAAAAAG TCAAAAAGAC CGTCTTTGGC AACAGAATTG TTTTGTTTTC CGCCATGAGA 3180
TTTACTAGAT GACTTTTTCG CGTCCCGTCC GTTAGAAAGC ATTGGAAGGA AATAACGAAA 3240
TGTTTCACTT GCTGAAGGAC CTGAACGAGC TGCTAACTTG CCGAGTCTTT TAAGCGTGTC 3300
ATTGTAAGCA CGAAGCTCTT TAATTTTATC TTTGGTTTCC TTTTTCTTAG CAATGGCATT 3360
TTTGAGATCA GTAATCCATG TATTTTTACT TTCTGGGTCT AGGGCTTCAA GTGTTTCTGA 3420
TTTACCATTG TTAAAATTGA TGGTGAATTT GTTTCCAGTA CCGGGTTCTA TGGATACTGC 3480
ATCAGTCTGA AAATACAGTT AGCACGGTTA AAACTAAAAA TCAGGGGAAT TAGGAATTCT 3540
TACCAAATTA ATGATTCCGC TTGGGACACT AGTTGATTGA GATTTGGAGT AAAAGAGTAA 3600
ACCACGGCAG TCTTGAGTAG CTTTAGCGAT ACGGTTAAGG TGATCATTAG CAGACTGGAA 3660
GAGGGAATCA GCATCAGAGT CGTGCATTTG CTCAGAAGCT AAGGAAGGTT CCGTTGGGTT 3720
ACCTTGCAAA GTACCATGGA AGTGTTTTTT ATAATAATGG TCTAATAAAT CCATAGACAT 3780
AGGGCCTTCT AGCATATAAA AATACCTTTT CATGACATGA CTACATGTGG TTAGTAAGAT 3840
TACTCAATCG ATTGTTTGAT TTTTAATAAA TGGATGCTGT TTTGACTTAC GGAATAAGTC 3900
CGTTGGATCG ACAGTATAAA TACCCACCAG TGGTGTAGGT CAATGGTTTT TCATCCTTGG 3960
CTTTCTTCTT GGATTTTTTT TCTTCAACCT TGGGAGCTGC CACGCTGTTT GGATCATCAT 4020
CTGCAGGATC GATATTGTCG ACTGTTTCAG GCTCCTTGGG TTCCTCAGGT GCTTGTACTT 4080
CTGCAGGAAC AGCGTTTTCA GTGGCATCAT CATTGTCGGT TTCGTTGCTC AATGGCACCT 4140
CCAGTGTCTC CACCTGGGCC TCAGCAGATC CCGAATCATG TTCATTGTGT TCCGACACAT 4200
TTTCGAAAGT AGGTTCAGCA ATCTGCTCAG GTCGTTCTTC ACGGCCCTCA TAAGACATGA 4260
TAAGAAGTCG AAAACAACAG TTAGGCTCTC AATTTTGGAT TTTTTTTATG CTGTAAATAT 4320
TTGTGGTAGA GGAAAAGTCT GCGCCAAGCT GGTTATTTGA ATACCAATTG TTGGCGAGAA 4380
TGTAAACAAA CAAATCGACT ACCTAATATA CAAACAAACG ATGGACATCA ATAGAAAAGG 4440
GAAAATACAT AGAATTTACT TTTTAAATGT TAAAAAATTT CTACTAATTC AT
4493Nucleotide Fasta Sequence
>SPBC428.08c.1:pep|Chromodomain|Schizosaccharomyces pombe
GTTGTTAACACCGTATTTCCTTTACGGGGCGATTCTCCGTTTCTTTAAATTTTGACTTCTGTAAAGGAGTGCGATTCAACAACCTGGTCGAAATACAAACTGTTATAACATGAATTGGCATTGCTAGTTTGGATTGTTGTTTGAAAGTTGATTTGTATATTATAACTTTAAAATTACTTTGTACTTGATACCTTTTTCAAATTTCAGAGCTTCAATTTTGCTCTGAAATTGAACACATCGACTTTATATATTTATTGCTCATTACTAAAAAACATTCAGTTTTATATTCTGAGTTCGCGGTCGTCTATTATTTTAGTCCTTTAGCAATTGTCATATTAACATAAACCCTCTCCTTATTTTATTTTTTAAATTCGTTCAGGCATCATTTGGAGGGTTTGCTAAAAATCATCTCACCAAACAAGAGGTTATTAGTTTTGCGAATGTCGCCTAAACAAGAGGAGTATGAAGTTGAAAGGATTGTGGACGAAAAATTGGATCGTAATGGAGCTGTCAAACTATATCGCATTCGATGGTTGAACTATTCATCTAGAAGTGATACTTGGGAGCCCCCTGAGAACCTTTCTGGATGTTCTGCCGTTTTAGCAGAATGGAAAAGGCGGAAGAGGAGACTAAAGGGAAGTAACTCCGACTCGGATTCACCGCACCATGCGAGCAATCCACATCCAAACAGTAGACAAAAGCACCAACATCAAACTTCAAAGTCAGTGCCTCGTTCTCAAAGATTTTCGCGGGAATTGAATGTAAAAAAGGAAAATAAAAAGGTTTTTTCTTCTCAAACTACCAAGAGACAATCTCGAAAACAATCCACCGCTCTGACGACGAATGATACTAGTATCATTTTAGACGATAGTCTTCATACAAATTCAAAGAAGCTGGGGAAGACGAGAAATGAAGTGAAGGAGGAATCTCAAAAAAGAGAACTAGTTTCCAATTCTATTAAAGAAGCTACATCCCCCAAAACATCTTCAATTCTCACAAAACCGCGAAACCCTTCCAAACTTGACTCTTATACCCATCTAAGTTTTTACGAAAAGAGAGAGCTATTTCGTAAGAAACTGCGGGAAATTGAAGGACCCGAAGTAACGCTTGTCAATGAAGTTGACGATGAACCCTGTCCATCTTTAGATTTTCAATTCATTAGCCAGTACCGCTTAACACAAGGTGTTATCCCGCCTGATCCAAATTTTCAATCTGGATGCAATTGCTCGTCCCTTGGCGGTTGTGACCTTAACAATCCTTCTCGTTGTGAGTGTTTAGATGATTTGGATGAGCCAACTCATTTTGCCTATGATGCACAGGGGCGGGTCCGTGCAGATACGGGTGCCGTTATATATGAATGCAACTCTTTTTGTTCTTGTTCAATGGAGTGTCCTAATCGCGTTGTTCAACGTGGTAGAACTCTTCCGCTTGAAATATTTAAAACAAAAGAAAAAGGATGGGGTGTACGTTCGCTTCGATTTGCCCCTGCTGGCACGTTTATCACTTGCTATTTAGGAGAAGTCATAACTTCAGCAGAGGCCGCCAAGCGTGACAAAAATTATGACGACGACGGTATTACCTATTTATTTGATTTAGACATGTTTGATGATGCTAGCGAGTATACAGTGGATGCTCAGAACTATGGAGATGTCTCTCGTTTTTTTAACCACTCCTGTTCACCTAATATAGCTATTTATTCTGCTGTTCGGAACCATGGATTTCGAACCATTTATGATCTCGCTTTTTTTGCCATCAAAGACATTCAGCCTCTAGAGGAGCTTACATTTGATTACGCTGGTGCAAAAGATTTCTCACCTGTTCAATCTCAAAAATCTCAGCAAAATAGAATTTCAAAACTTCGCCGGCAGTGCAAATGTGGTTCCGCTAATTGTCGTGGCTGGCTTTTCGGTTAAGCTAATTTATTACTGGTTGACTCCAATAATTACAATTTGTTTTTCTCCATTACTGTTAAACTGAAAAAGGTCATTCATTTTCTAAGCAACGAGATTATGTATATTATCTGACCTGTGGGATTTGCCGAACAATTATCGGTAAAACATATCGGTGCTTATATTTTTTACACTTGTTGAAAGCATTATAGTAATTGTTGTAAAGCCTAGCGTTAATGGAAAAACTCTTTTCATCTGCTGCGCACATGTGAAGTAAAAAGGGCGTTTAAGCGTTAACGGTAATGGACCGTCCTTCAGAAGCTATAGAAGGAGCTGCTTCTGTTTCGAGCACCTGGGGCATCTGATTGTTTTCTCCTTCTGCTGAGGCGAGGGCATCAGTTGTTTCTTCAGCTGGGTCTTCTTGTGCAGCTGTTCGAGGCGTTGGAGTTGTTGTAGGAGTTAAGGGAGTTTCCGGTTTTATTGTGGTTTTTGAGAACTGGGAAATTTCTTTTAGTCTCCCGTCTTTATCAAACTTCTTATGCACTTTTTTTTGCACCAAACCTGAGAGCTTCTTTGAAAGGTTGGAAGGAAATATCTCAAATCCTGCCTTAGCAAATTCAAGGGAAGGATCTGCCTGTAAAGTTTTAACACTTTTGGTAGGTTTAGCATACTTGTGAAGCTTAAAGCCGAATACTCTCTTGTTGCCTCCTTTTTTCTTCTTATGATGCCGATGATGCTTTTTTCCGGCTTTCTTAGACGTTCTATCTTCATTGCTGACAACACTCTCTTCATTAGTAGCTGCAGTGGAAGGGTCTTGATCGTCTGCAGTAGGGGTCGCAACATCGGGAAGTGCTATATCAGGAAGTGCAATATCAGTCTCTTCTATGAAAGCTTGTTCAACTGATTGGGCTGTACCTTTAACATCTTCTTCAATGGCGTCTGCTATTTGACCGATGGGGGTTCCGTTATCATTTTGAGTAGAAGCTTGCTCAACATTTTGAGTTGATGTTGATTCTTCTGCCGGACCTGTGGCTGGTTTTTCTTCTGATGCGGGAGCCACTTCTTCCGTAGTAGCAGGAAAATGTTCTTCAGTGGTGGGAATTTGGTTAGTTTCATTCTCAGGAACTTCGACTGATTGTGCTTCAACAGTAGTATCAACCGGGTCAGCTGACGTTTCATTATCAATGGGACTAGCCGTATCGTTTTGCGGAGTTTTCCCCTTAATCATGTTTTGAAAAAAGTCAAAAAGACCGTCTTTGGCAACAGAATTGTTTTGTTTTCCGCCATGAGATTTACTAGATGACTTTTTCGCGTCCCGTCCGTTAGAAAGCATTGGAAGGAAATAACGAAATGTTTCACTTGCTGAAGGACCTGAACGAGCTGCTAACTTGCCGAGTCTTTTAAGCGTGTCATTGTAAGCACGAAGCTCTTTAATTTTATCTTTGGTTTCCTTTTTCTTAGCAATGGCATTTTTGAGATCAGTAATCCATGTATTTTTACTTTCTGGGTCTAGGGCTTCAAGTGTTTCTGATTTACCATTGTTAAAATTGATGGTGAATTTGTTTCCAGTACCGGGTTCTATGGATACTGCATCAGTCTGAAAATACAGTTAGCACGGTTAAAACTAAAAATCAGGGGAATTAGGAATTCTTACCAAATTAATGATTCCGCTTGGGACACTAGTTGATTGAGATTTGGAGTAAAAGAGTAAACCACGGCAGTCTTGAGTAGCTTTAGCGATACGGTTAAGGTGATCATTAGCAGACTGGAAGAGGGAATCAGCATCAGAGTCGTGCATTTGCTCAGAAGCTAAGGAAGGTTCCGTTGGGTTACCTTGCAAAGTACCATGGAAGTGTTTTTTATAATAATGGTCTAATAAATCCATAGACATAGGGCCTTCTAGCATATAAAAATACCTTTTCATGACATGACTACATGTGGTTAGTAAGATTACTCAATCGATTGTTTGATTTTTAATAAATGGATGCTGTTTTGACTTACGGAATAAGTCCGTTGGATCGACAGTATAAATACCCACCAGTGGTGTAGGTCAATGGTTTTTCATCCTTGGCTTTCTTCTTGGATTTTTTTTCTTCAACCTTGGGAGCTGCCACGCTGTTTGGATCATCATCTGCAGGATCGATATTGTCGACTGTTTCAGGCTCCTTGGGTTCCTCAGGTGCTTGTACTTCTGCAGGAACAGCGTTTTCAGTGGCATCATCATTGTCGGTTTCGTTGCTCAATGGCACCTCCAGTGTCTCCACCTGGGCCTCAGCAGATCCCGAATCATGTTCATTGTGTTCCGACACATTTTCGAAAGTAGGTTCAGCAATCTGCTCAGGTCGTTCTTCACGGCCCTCATAAGACATGATAAGAAGTCGAAAACAACAGTTAGGCTCTCAATTTTGGATTTTTTTTATGCTGTAAATATTTGTGGTAGAGGAAAAGTCTGCGCCAAGCTGGTTATTTGAATACCAATTGTTGGCGAGAATGTAAACAAACAAATCGACTACCTAATATACAAACAAACGATGGACATCAATAGAAAAGGGAAAATACATAGAATTTACTTTTTAAATGTTAAAAAATTTCTACTAATTCAT
|
| Sequence Source |
Ensembl |
| Keyword |
KW-0002--3D-structure
KW-0156--Chromatin regulator
KW-0158--Chromosome
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0206--Cytoskeleton
KW-0903--Direct protein sequencing
KW-0479--Metal-binding
KW-0489--Methyltransferase
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0949--S-adenosyl-L-methionine
KW-0808--Transferase
KW-0862--Zinc
--
|
| Interpro |
IPR000953--Chromo/shadow_dom
IPR023780--Chromo_domain
IPR016197--Chromodomain-like
IPR023779--Chromodomain_CS
IPR011381--Histone_H3-K9_MeTrfase
IPR003616--Post-SET_dom
IPR007728--Pre-SET_dom
IPR001214--SET_dom
|
| PROSITE |
PS00598--CHROMO_1
PS50013--CHROMO_2
PS50868--POST_SET
PS50867--PRE_SET
PS50280--SET
|
| Pfam |
PF00385--Chromo
PF05033--Pre-SET
PF00856--SET
|
| Gene Ontology |
GO:0034507--C:chromosome, centromeric outer repeat region
GO:0000781--C:chromosome, telomeric region
GO:0043494--C:CLRC ubiquitin ligase complex
GO:0005737--C:cytoplasm
GO:0031934--C:mating-type region heterochromatin
GO:0044732--C:mitotic spindle pole body
GO:0031618--C:nuclear pericentric heterochromatin
GO:1990707--C:nuclear subtelomeric heterochromatin
GO:0005634--C:nucleus
GO:0003690--F:double-stranded DNA binding
GO:0042054--F:histone methyltransferase activity
GO:0046974--F:histone methyltransferase activity (H3-K9 specific)
GO:0035064--F:methylated histone binding
GO:0008168--F:methyltransferase activity
GO:0003697--F:single-stranded DNA binding
GO:0003727--F:single-stranded RNA binding
GO:0008270--F:zinc ion binding
GO:0034613--P:cellular protein localization
GO:0006338--P:chromatin remodeling
GO:0030702--P:chromatin silencing at centromere
GO:1990141--P:chromatin silencing at centromere outer repeat region
GO:0000183--P:chromatin silencing at rDNA
GO:0030466--P:chromatin silencing at silent mating-type cassette
GO:0006348--P:chromatin silencing at telomere
GO:0031048--P:chromatin silencing by small RNA
GO:0007535--P:donor selection
GO:1902368--P:heterochromatin maintenance involved in chromatin silencing at centromere outer repeat region
GO:0051567--P:histone H3-K9 methylation
GO:0045141--P:meiotic telomere clustering
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0090065--P:regulation of production of siRNA involved in RNA interference
|
| Orthology |
|
| Created Date |
25-Jun-2016 |
