| Tag |
Content |
| WERAM ID |
WERAM-Cae-0064 |
| Ensembl Protein ID |
R05D3.11 |
| Uniprot Accession |
P34544; MET2_CAEEL; Q8WTP5
|
| Genbank Protein ID |
NP_498848.4
|
| Protein Name |
Histone-lysine N-methyltransferase met-2 |
| Genbank Nucleotide ID |
NM_066447.5
|
| Gene Name |
MET2;set-25 |
| Ensembl Information |
|
| Details |
| Type |
Family |
Domain |
Substrates |
AA |
References (PMIDs) |
| HMT |
SUV39 |
SET |
H3K9 |
K |
20107519; 22939621
|
|
| Status |
Reviewed |
| Classification |
| Type |
Family |
E-value |
Score |
Start |
End |
| HMT |
SUV39 |
9.30e-55 |
185.3 |
728 |
1277 |
|
| Organism |
Caenorhabditis elegans |
| NCBI Taxa ID |
6239 |
Functional Description
(View)Functional Description
Histone methyltransferase which is required for the mono- and dimethylation of 'Lys-9' of histone H3. This increases the efficiency of set-25-mediated trimethylation of histone H3 'Lys-9'. Involved in the transcriptional repression of lin-3 which is required for the negative regulation of vulval cell fate specification during postembryonic development. Has a role in blocking checkpoint signaling and mediating the transcriptional silencing of meiotic sex chromosome inactivation; a mechanism which enables checkpoint proteins to distinguish between the partnerless male X chromosome and asynapsed chromosomes thereby shielding the lone X from inappropriate activation of an apoptotic program. Operates redundantly with set-25 to position chromatin at the nuclear periphery. |
Histone methyltransferase which is required for the mono- and dimethylation of 'Lys-9' of histone H3. This increases the efficiency of set-25-mediated trimethylation of histone H3 'Lys-9'. Involved in the transcriptional repression of lin-3 which is required for the negative regulation of vulval cell fate specification during postembryonic development. Has a role in blocking checkpoint signaling and mediating the transcriptional silencing of meiotic sex chromosome inactivation; a mechanism which enables checkpoint proteins to distinguish between the partnerless male X chromosome and asynapsed chromosomes thereby shielding the lone X from inappropriate activation of an apoptotic program. Operates redundantly with set-25 to position chromatin at the nuclear periphery.
|
| Domain Profile |
HMT SUV39
SUV39.txt 36 tddeaekegleegdeyladldskesv.enlkegyesdvplssdssntrqekdkeese 91
t+++ +++ ++ ++ + +d+++s+ e+++++++++ ++++++ +++ k+++e
R05D3.11 728 TNNNLSQRRKDQLQSQFEPTDMIRSMpERNHQQVVKKKTTGTNQNVASTNDAKSKRE 784
566666666677777777778887776666666666666666655444444444433 PP
SUV39.txt 2 rLqvfktenkGwGvrclddiakgsFvciyaGeiltddeaekegleegdeyladldskesv..enlkegyesdvplssdss.................. 79
++++fkt+++GwGvr+l+di++++F+c+y+G iltdd a++ ++ d+y+adld k++v e+ +e++e+d+ ++ d+s
R05D3.11 1053 PMHIFKTAQSGWGVRALTDIPQSTFICTYVGAILTDDLADEL--RNADQYFADLDLKDTVelEKGREDHETDFGYGGDESdyddeegsdgdsgddvmn 1148
699*************************************88..***************9999*********************************** PP
SUV39.txt 80 ...........................................................ntrqekdkeeseyiidakkegnvgrflnHscspNlfvqn 118
n++ ++++ y+idak++gn+grflnHsc+pN++vq+
R05D3.11 1149 kmvkrqdssesgeetkrltrqkrkqskksgkggsvekddttprdsmekdnieskdepvfNWD-KYFEPFPLYVIDAKQRGNLGRFLNHSCDPNVHVQH 1245
********************************************************996555.56679****************************** PP
SUV39.txt 119 vfvdthdlrfprvafFaskrikagtELtwdYg 150
v++dthdlr+p+vafF++k++kag+ELtwdY+
R05D3.11 1246 VMYDTHDLRLPWVAFFTRKYVKAGDELTWDYQ 1277
*******************************7 PP
|
Protein Sequence
(Fasta) | MDQQEPSNNV DTSSILSDDG METQEQSSFV TATIDLTVDD YDETEIQEIL DNGKAEEGTD 60
EDSDLVEGIL NANSDVQALL DAPSEQVAQA LNSFFGNESE QEAVAAQRRV DAEKTAKDEA 120
ELKQQEEAED LIIEDSIVKT DEEKQAVRRL KINEFLSWFT RLLPEQFKNF EFTNPNYLTE 180
SISDSPVVNV DKCKEIVKSF KESESLEGLS QKYELIDEDV LVAAICIGVL DTNNEEDVDF 240
NVLCDDRIDD WSIEKCVTFL DYPNTGLNSK NGPLRFMQFT VTSPASAILM LTLIRLREEG 300
HPCRLDFDSN PTDDLLLNFD QVEFSNNIID TAVKYWDDQK ENGAQDKIGR ELNDFFHEIE 360
STSAEFKQHF ENAVGSRNEI IQLVNEKIPD FDGTEAAVNE SFTSDQRTEI INSRAIMETL 420
KAEMKLAIAE AQKVYDTKTD FEKFFVLTVG DFCLARANPS DDAELTYAIV QDRVDAMTYK 480
VKFIDTSQIR ECNIRDLAMT TQGMYDPSLN TFGDVGLRVA CRQVISSSQF GKKTIWLTGT 540
AAGRRRAHRS DFLIFFDNGT DAYVSAPTMP GEPGYEVASE KKSVFSLKEM IAKMNAAQIA 600
IMVGQPVGKE GNLDYFLTFH WIRQSHRSAY IRDFMKEFPE WPLLKMPVGM RICLYNSLVD 660
RRKKMVTVIG TDRAFAIVRH EAPNPLAPGN RCTDFPCNDR NHQHIDEKIY RGSHRLEGAA 720
HKKHMISTNN NLSQRRKDQL QSQFEPTDMI RSMPERNHQQ VVKKKTTGTN QNVASTNDAK 780
SKREIEIRKK NQFLFNKIIV PIPVLTPLEN LKAHAQCGPD CLQKMDADPY EARFHRNSPI 840
HTPLLCGWRR IMYTMSTGKK RGAVKKNIIY FSPCGAALHQ ISDVSEYIHV TRSLLTIDCF 900
SFDARIDTAT YITVDDKYLK VADFSLGTEG IPIPLVNSVD NDEPPSLEYS KRRFQYNDQV 960
DISSVSRDFC SGCSCDGDCS DASKCECQQL SIEAMKRLPH NLQFDGHDEL VPHYQNRLLS 1020
SKVISGLYEC NDQCSCHRKS CYNRVVQNNI KYPMHIFKTA QSGWGVRALT DIPQSTFICT 1080
YVGAILTDDL ADELRNADQY FADLDLKDTV ELEKGREDHE TDFGYGGDES DYDDEEGSDG 1140
DSGDDVMNKM VKRQDSSESG EETKRLTRQK RKQSKKSGKG GSVEKDDTTP RDSMEKDNIE 1200
SKDEPVFNWD KYFEPFPLYV IDAKQRGNLG RFLNHSCDPN VHVQHVMYDT HDLRLPWVAF 1260
FTRKYVKAGD ELTWDYQYTQ DQTATTQLTC HCGAENCTGR LLKS 1304Protein Fasta Sequence
>R05D3.11|MET2;set-25|Caenorhabditis elegans
MDQQEPSNNVDTSSILSDDGMETQEQSSFVTATIDLTVDDYDETEIQEILDNGKAEEGTDEDSDLVEGILNANSDVQALLDAPSEQVAQALNSFFGNESEQEAVAAQRRVDAEKTAKDEAELKQQEEAEDLIIEDSIVKTDEEKQAVRRLKINEFLSWFTRLLPEQFKNFEFTNPNYLTESISDSPVVNVDKCKEIVKSFKESESLEGLSQKYELIDEDVLVAAICIGVLDTNNEEDVDFNVLCDDRIDDWSIEKCVTFLDYPNTGLNSKNGPLRFMQFTVTSPASAILMLTLIRLREEGHPCRLDFDSNPTDDLLLNFDQVEFSNNIIDTAVKYWDDQKENGAQDKIGRELNDFFHEIESTSAEFKQHFENAVGSRNEIIQLVNEKIPDFDGTEAAVNESFTSDQRTEIINSRAIMETLKAEMKLAIAEAQKVYDTKTDFEKFFVLTVGDFCLARANPSDDAELTYAIVQDRVDAMTYKVKFIDTSQIRECNIRDLAMTTQGMYDPSLNTFGDVGLRVACRQVISSSQFGKKTIWLTGTAAGRRRAHRSDFLIFFDNGTDAYVSAPTMPGEPGYEVASEKKSVFSLKEMIAKMNAAQIAIMVGQPVGKEGNLDYFLTFHWIRQSHRSAYIRDFMKEFPEWPLLKMPVGMRICLYNSLVDRRKKMVTVIGTDRAFAIVRHEAPNPLAPGNRCTDFPCNDRNHQHIDEKIYRGSHRLEGAAHKKHMISTNNNLSQRRKDQLQSQFEPTDMIRSMPERNHQQVVKKKTTGTNQNVASTNDAKSKREIEIRKKNQFLFNKIIVPIPVLTPLENLKAHAQCGPDCLQKMDADPYEARFHRNSPIHTPLLCGWRRIMYTMSTGKKRGAVKKNIIYFSPCGAALHQISDVSEYIHVTRSLLTIDCFSFDARIDTATYITVDDKYLKVADFSLGTEGIPIPLVNSVDNDEPPSLEYSKRRFQYNDQVDISSVSRDFCSGCSCDGDCSDASKCECQQLSIEAMKRLPHNLQFDGHDELVPHYQNRLLSSKVISGLYECNDQCSCHRKSCYNRVVQNNIKYPMHIFKTAQSGWGVRALTDIPQSTFICTYVGAILTDDLADELRNADQYFADLDLKDTVELEKGREDHETDFGYGGDESDYDDEEGSDGDSGDDVMNKMVKRQDSSESGEETKRLTRQKRKQSKKSGKGGSVEKDDTTPRDSMEKDNIESKDEPVFNWDKYFEPFPLYVIDAKQRGNLGRFLNHSCDPNVHVQHVMYDTHDLRLPWVAFFTRKYVKAGDELTWDYQYTQDQTATTQLTCHCGAENCTGRLLKS |
Nucleotide Sequence
(Fasta) | AGATGGACCA ACAAGAACCA TCGAATAACG TAGATACGAG CAGTATTCTT TCGGATGATG 60
GGATGGAAAC ACAGGAACAA AGTTCATTCG TCACTGCTAC AATTGACCTA ACAGTGGACG 120
ACTACGATGA AACAGAAATA CAGGAGATTC TGGATAATGG AAAAGCAGAA GAAGGAACAG 180
ATGAAGATTC TGATTTAGTT GAAGGGATTC TTAACGCTAA TTCAGATGTC CAAGCGCTCC 240
TTGATGCGCC ATCTGAGCAA GTAGCTCAAG CTCTTAATTC GTTCTTCGGA AATGAGAGTG 300
AACAAGAAGC TGTTGCAGCA CAAAGACGGG TTGATGCGGA GAAGACTGCC AAAGATGAAG 360
CTGAACTCAA GCAACAGGAA GAGGCGGAAG ATCTTATTAT AGAAGATTCG ATAGTCAAAA 420
CTGATGAAGA AAAACAAGCA GTTCGAAGAC TGAAAATCAA CGAATTTTTA TCGTGGTTCA 480
CAAGGCTCCT TCCAGAACAA TTTAAAAATT TCGAATTCAC AAATCCGAAC TATCTGACAG 540
AATCTATCAG CGATTCACCG GTTGTAAATG TCGATAAATG CAAGGAAATT GTCAAATCGT 600
TCAAGGAAAG TGAATCACTT GAGGGACTTT CACAGAAATA CGAATTAATT GATGAAGACG 660
TGCTAGTCGC TGCTATTTGT ATTGGCGTTC TCGATACCAA CAACGAAGAA GATGTCGACT 720
TTAATGTTCT ATGTGATGAT CGTATCGACG ATTGGAGTAT AGAAAAATGT GTCACTTTTC 780
TTGATTATCC AAATACTGGA TTGAATTCGA AAAATGGACC GTTGAGATTC ATGCAGTTTA 840
CTGTCACATC ACCTGCATCA GCAATTCTCA TGCTCACTCT GATTCGATTA CGCGAAGAAG 900
GGCATCCGTG TCGATTAGAT TTTGATTCAA ATCCGACTGA TGATTTACTC TTGAATTTCG 960
ATCAAGTGGA ATTTTCTAAT AATATCATTG ATACGGCAGT CAAATACTGG GATGATCAGA 1020
AGGAAAACGG TGCGCAGGAT AAAATTGGCA GAGAGCTCAA CGACTTCTTC CACGAAATCG 1080
AGTCAACATC AGCAGAATTC AAACAACATT TTGAGAACGC CGTTGGCAGC CGTAATGAAA 1140
TAATTCAACT TGTCAACGAG AAAATTCCCG ATTTTGATGG CACTGAGGCT GCTGTGAATG 1200
AGAGTTTTAC ATCCGATCAA CGAACCGAAA TTATCAACTC TCGTGCAATA ATGGAGACAT 1260
TAAAAGCCGA GATGAAGCTC GCCATCGCCG AAGCTCAGAA AGTTTACGAC ACCAAGACTG 1320
ACTTCGAAAA ATTCTTCGTT TTGACAGTTG GAGATTTCTG TCTGGCTCGC GCCAATCCTT 1380
CTGACGATGC AGAATTAACA TACGCCATAG TTCAGGATCG TGTGGATGCA ATGACCTATA 1440
AGGTTAAATT TATCGACACA AGTCAGATCA GAGAGTGTAA CATCAGAGAT TTAGCCATGA 1500
CTACGCAGGG AATGTATGAC CCGAGTTTGA ATACATTTGG TGATGTTGGT CTTCGAGTTG 1560
CCTGTCGCCA AGTTATTTCC TCGAGCCAAT TTGGAAAAAA AACAATTTGG CTTACCGGTA 1620
CAGCTGCCGG ACGTCGCAGA GCTCATAGAT CCGATTTTCT AATTTTCTTC GACAACGGAA 1680
CCGATGCATA CGTGTCAGCT CCGACAATGC CTGGTGAACC AGGTTATGAA GTTGCTTCTG 1740
AAAAGAAAAG TGTATTTTCT CTCAAAGAAA TGATTGCGAA GATGAATGCT GCTCAGATTG 1800
CTATTATGGT TGGACAGCCA GTAGGAAAGG AAGGAAATCT GGATTATTTT TTGACATTTC 1860
ATTGGATTCG ACAATCTCAC AGATCAGCGT ATATTCGGGA TTTTATGAAA GAATTTCCGG 1920
AATGGCCACT TCTCAAGATG CCAGTTGGAA TGCGAATCTG TTTGTACAAT TCTCTTGTTG 1980
ATCGACGTAA GAAAATGGTG ACAGTGATTG GAACTGATCG AGCTTTTGCT ATTGTGAGAC 2040
ACGAAGCACC GAATCCATTG GCTCCTGGGA ATAGATGTAC AGACTTTCCG TGCAATGATA 2100
GAAATCATCA GCATATTGAC GAGAAAATCT ATAGAGGATC TCATAGATTG GAAGGCGCAG 2160
CGCACAAGAA GCACATGATC TCGACAAATA ACAATCTGTC GCAACGCAGA AAAGACCAGC 2220
TTCAATCACA GTTCGAGCCA ACCGACATGA TTCGTTCGAT GCCAGAGAGG AATCACCAAC 2280
AAGTCGTTAA AAAGAAAACG ACGGGCACCA ATCAGAATGT CGCTTCGACA AATGATGCAA 2340
AATCGAAGAG AGAAATTGAA ATAAGAAAGA AAAATCAATT CTTATTTAAC AAGATTATTG 2400
TTCCAATACC CGTCCTAACA CCATTGGAAA ATCTCAAGGC TCATGCTCAA TGTGGTCCAG 2460
ATTGTCTACA GAAAATGGAT GCGGATCCGT ATGAAGCAAG ATTCCATCGA AATTCACCAA 2520
TACATACTCC TCTTTTGTGT GGTTGGAGAC GAATTATGTA CACAATGAGT ACTGGAAAGA 2580
AGCGGGGAGC AGTGAAGAAA AACATTATTT ACTTTTCTCC ATGCGGAGCC GCTCTTCACC 2640
AGATCAGCGA CGTCTCTGAA TATATTCATG TCACCAGAAG TTTATTGACG ATTGATTGTT 2700
TTTCATTTGA TGCACGAATC GATACTGCCA CTTATATTAC TGTTGACGAT AAATATTTGA 2760
AGGTTGCTGA TTTTTCGCTT GGAACCGAAG GAATCCCAAT TCCACTAGTG AACAGCGTGG 2820
ATAACGATGA GCCTCCATCA TTGGAATATT CGAAACGACG ATTCCAATAC AATGATCAAG 2880
TGGATATATC GAGTGTTAGC CGAGATTTCT GTTCTGGATG CTCTTGTGAT GGTGATTGCA 2940
GTGACGCATC GAAGTGTGAA TGCCAACAAT TGTCCATTGA AGCAATGAAA CGACTCCCCC 3000
ATAATTTACA ATTCGACGGA CACGACGAAT TAGTTCCTCA CTATCAAAAT CGTCTTCTCA 3060
GCAGTAAGGT TATCAGTGGA CTCTATGAAT GCAACGATCA GTGTTCATGC CATCGAAAGT 3120
CTTGTTACAA CAGAGTTGTT CAGAACAATA TCAAGTATCC TATGCATATC TTCAAAACTG 3180
CTCAATCCGG ATGGGGAGTC CGAGCTTTGA CGGATATTCC TCAAAGTACG TTCATTTGCA 3240
CGTATGTAGG TGCTATACTG ACGGATGATT TGGCTGATGA ACTAAGAAAT GCGGATCAAT 3300
ACTTCGCTGA TTTGGACTTG AAGGATACCG TGGAGCTGGA AAAGGGTCGC GAAGATCATG 3360
AAACTGATTT TGGTTACGGA GGAGACGAGT CAGATTATGA TGACGAAGAA GGAAGTGATG 3420
GTGACTCCGG TGATGATGTA ATGAACAAAA TGGTGAAACG TCAAGACTCT TCGGAGAGTG 3480
GTGAAGAAAC AAAACGGCTG ACAAGACAGA AAAGAAAGCA ATCTAAAAAA TCCGGTAAAG 3540
GAGGAAGTGT GGAGAAAGAT GACACCACTC CAAGAGATTC AATGGAAAAG GATAATATTG 3600
AAAGTAAAGA CGAACCCGTT TTCAATTGGG ATAAGTATTT TGAGCCGTTT CCATTGTATG 3660
TTATAGATGC AAAACAGAGA GGAAATCTTG GAAGATTCTT GAATCACTCT TGCGATCCGA 3720
ATGTGCACGT TCAACACGTC ATGTACGATA CGCATGATCT TCGTCTTCCA TGGGTCGCGT 3780
TTTTCACACG AAAATACGTG AAAGCCGGCG ATGAGCTAAC CTGGGACTAT CAATATACTC 3840
AAGATCAGAC GGCTACCACA CAACTCACAT GCCACTGCGG AGCTGAAAAC TGCACCGGCC 3900
GTTTGCTGAA AAGTTAAAGA ATTGTTGTTA TTTCCTTCCC AGTTATGTTT TCCTTTTTTT 3960
TTAAGTATTT ATTTATTTAT TTAATTTTTA TTTTGTTTAT TGTTCAATCG TTTAAAATCT 4020
CCCTTTGAAA ACAGCATCTC ATATGTATGA TCTAAACACG TATTTACCTC GTAAGGGTTT 4080
GCCAAATAGT TTCTTTGGTT TTCATTTTGA TTTTCTCTGC GAATAAAATG TTTT
4135Nucleotide Fasta Sequence
>R05D3.11|SUV39|Caenorhabditis elegans
AGATGGACCAACAAGAACCATCGAATAACGTAGATACGAGCAGTATTCTTTCGGATGATGGGATGGAAACACAGGAACAAAGTTCATTCGTCACTGCTACAATTGACCTAACAGTGGACGACTACGATGAAACAGAAATACAGGAGATTCTGGATAATGGAAAAGCAGAAGAAGGAACAGATGAAGATTCTGATTTAGTTGAAGGGATTCTTAACGCTAATTCAGATGTCCAAGCGCTCCTTGATGCGCCATCTGAGCAAGTAGCTCAAGCTCTTAATTCGTTCTTCGGAAATGAGAGTGAACAAGAAGCTGTTGCAGCACAAAGACGGGTTGATGCGGAGAAGACTGCCAAAGATGAAGCTGAACTCAAGCAACAGGAAGAGGCGGAAGATCTTATTATAGAAGATTCGATAGTCAAAACTGATGAAGAAAAACAAGCAGTTCGAAGACTGAAAATCAACGAATTTTTATCGTGGTTCACAAGGCTCCTTCCAGAACAATTTAAAAATTTCGAATTCACAAATCCGAACTATCTGACAGAATCTATCAGCGATTCACCGGTTGTAAATGTCGATAAATGCAAGGAAATTGTCAAATCGTTCAAGGAAAGTGAATCACTTGAGGGACTTTCACAGAAATACGAATTAATTGATGAAGACGTGCTAGTCGCTGCTATTTGTATTGGCGTTCTCGATACCAACAACGAAGAAGATGTCGACTTTAATGTTCTATGTGATGATCGTATCGACGATTGGAGTATAGAAAAATGTGTCACTTTTCTTGATTATCCAAATACTGGATTGAATTCGAAAAATGGACCGTTGAGATTCATGCAGTTTACTGTCACATCACCTGCATCAGCAATTCTCATGCTCACTCTGATTCGATTACGCGAAGAAGGGCATCCGTGTCGATTAGATTTTGATTCAAATCCGACTGATGATTTACTCTTGAATTTCGATCAAGTGGAATTTTCTAATAATATCATTGATACGGCAGTCAAATACTGGGATGATCAGAAGGAAAACGGTGCGCAGGATAAAATTGGCAGAGAGCTCAACGACTTCTTCCACGAAATCGAGTCAACATCAGCAGAATTCAAACAACATTTTGAGAACGCCGTTGGCAGCCGTAATGAAATAATTCAACTTGTCAACGAGAAAATTCCCGATTTTGATGGCACTGAGGCTGCTGTGAATGAGAGTTTTACATCCGATCAACGAACCGAAATTATCAACTCTCGTGCAATAATGGAGACATTAAAAGCCGAGATGAAGCTCGCCATCGCCGAAGCTCAGAAAGTTTACGACACCAAGACTGACTTCGAAAAATTCTTCGTTTTGACAGTTGGAGATTTCTGTCTGGCTCGCGCCAATCCTTCTGACGATGCAGAATTAACATACGCCATAGTTCAGGATCGTGTGGATGCAATGACCTATAAGGTTAAATTTATCGACACAAGTCAGATCAGAGAGTGTAACATCAGAGATTTAGCCATGACTACGCAGGGAATGTATGACCCGAGTTTGAATACATTTGGTGATGTTGGTCTTCGAGTTGCCTGTCGCCAAGTTATTTCCTCGAGCCAATTTGGAAAAAAAACAATTTGGCTTACCGGTACAGCTGCCGGACGTCGCAGAGCTCATAGATCCGATTTTCTAATTTTCTTCGACAACGGAACCGATGCATACGTGTCAGCTCCGACAATGCCTGGTGAACCAGGTTATGAAGTTGCTTCTGAAAAGAAAAGTGTATTTTCTCTCAAAGAAATGATTGCGAAGATGAATGCTGCTCAGATTGCTATTATGGTTGGACAGCCAGTAGGAAAGGAAGGAAATCTGGATTATTTTTTGACATTTCATTGGATTCGACAATCTCACAGATCAGCGTATATTCGGGATTTTATGAAAGAATTTCCGGAATGGCCACTTCTCAAGATGCCAGTTGGAATGCGAATCTGTTTGTACAATTCTCTTGTTGATCGACGTAAGAAAATGGTGACAGTGATTGGAACTGATCGAGCTTTTGCTATTGTGAGACACGAAGCACCGAATCCATTGGCTCCTGGGAATAGATGTACAGACTTTCCGTGCAATGATAGAAATCATCAGCATATTGACGAGAAAATCTATAGAGGATCTCATAGATTGGAAGGCGCAGCGCACAAGAAGCACATGATCTCGACAAATAACAATCTGTCGCAACGCAGAAAAGACCAGCTTCAATCACAGTTCGAGCCAACCGACATGATTCGTTCGATGCCAGAGAGGAATCACCAACAAGTCGTTAAAAAGAAAACGACGGGCACCAATCAGAATGTCGCTTCGACAAATGATGCAAAATCGAAGAGAGAAATTGAAATAAGAAAGAAAAATCAATTCTTATTTAACAAGATTATTGTTCCAATACCCGTCCTAACACCATTGGAAAATCTCAAGGCTCATGCTCAATGTGGTCCAGATTGTCTACAGAAAATGGATGCGGATCCGTATGAAGCAAGATTCCATCGAAATTCACCAATACATACTCCTCTTTTGTGTGGTTGGAGACGAATTATGTACACAATGAGTACTGGAAAGAAGCGGGGAGCAGTGAAGAAAAACATTATTTACTTTTCTCCATGCGGAGCCGCTCTTCACCAGATCAGCGACGTCTCTGAATATATTCATGTCACCAGAAGTTTATTGACGATTGATTGTTTTTCATTTGATGCACGAATCGATACTGCCACTTATATTACTGTTGACGATAAATATTTGAAGGTTGCTGATTTTTCGCTTGGAACCGAAGGAATCCCAATTCCACTAGTGAACAGCGTGGATAACGATGAGCCTCCATCATTGGAATATTCGAAACGACGATTCCAATACAATGATCAAGTGGATATATCGAGTGTTAGCCGAGATTTCTGTTCTGGATGCTCTTGTGATGGTGATTGCAGTGACGCATCGAAGTGTGAATGCCAACAATTGTCCATTGAAGCAATGAAACGACTCCCCCATAATTTACAATTCGACGGACACGACGAATTAGTTCCTCACTATCAAAATCGTCTTCTCAGCAGTAAGGTTATCAGTGGACTCTATGAATGCAACGATCAGTGTTCATGCCATCGAAAGTCTTGTTACAACAGAGTTGTTCAGAACAATATCAAGTATCCTATGCATATCTTCAAAACTGCTCAATCCGGATGGGGAGTCCGAGCTTTGACGGATATTCCTCAAAGTACGTTCATTTGCACGTATGTAGGTGCTATACTGACGGATGATTTGGCTGATGAACTAAGAAATGCGGATCAATACTTCGCTGATTTGGACTTGAAGGATACCGTGGAGCTGGAAAAGGGTCGCGAAGATCATGAAACTGATTTTGGTTACGGAGGAGACGAGTCAGATTATGATGACGAAGAAGGAAGTGATGGTGACTCCGGTGATGATGTAATGAACAAAATGGTGAAACGTCAAGACTCTTCGGAGAGTGGTGAAGAAACAAAACGGCTGACAAGACAGAAAAGAAAGCAATCTAAAAAATCCGGTAAAGGAGGAAGTGTGGAGAAAGATGACACCACTCCAAGAGATTCAATGGAAAAGGATAATATTGAAAGTAAAGACGAACCCGTTTTCAATTGGGATAAGTATTTTGAGCCGTTTCCATTGTATGTTATAGATGCAAAACAGAGAGGAAATCTTGGAAGATTCTTGAATCACTCTTGCGATCCGAATGTGCACGTTCAACACGTCATGTACGATACGCATGATCTTCGTCTTCCATGGGTCGCGTTTTTCACACGAAAATACGTGAAAGCCGGCGATGAGCTAACCTGGGACTATCAATATACTCAAGATCAGACGGCTACCACACAACTCACATGCCACTGCGGAGCTGAAAACTGCACCGGCCGTTTGCTGAAAAGTTAAAGAATTGTTGTTATTTCCTTCCCAGTTATGTTTTCCTTTTTTTTTAAGTATTTATTTATTTATTTAATTTTTATTTTGTTTATTGTTCAATCGTTTAAAATCTCCCTTTGAAAACAGCATCTCATATGTATGATCTAAACACGTATTTACCTCGTAAGGGTTTGCCAAATAGTTTCTTTGGTTTTCATTTTGATTTTCTCTGCGAATAAAATGTTTT
|
| Sequence Source |
Ensembl |
| Keyword |
KW-0158--Chromosome
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0221--Differentiation
KW-0469--Meiosis
KW-0479--Metal-binding
KW-0489--Methyltransferase
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0677--Repeat
KW-0949--S-adenosyl-L-methionine
KW-0726--Sexual differentiation
KW-0804--Transcription
KW-0805--Transcription regulation
KW-0808--Transferase
KW-0862--Zinc
--
|
| Interpro |
IPR016177--DNA-bd_dom
IPR001739--Methyl_CpG_DNA-bd
IPR003616--Post-SET_dom
IPR007728--Pre-SET_dom
IPR001214--SET_dom
|
| PROSITE |
PS50982--MBD
PS50868--POST_SET
PS50867--PRE_SET
PS50280--SET
|
| Pfam |
PF01429--MBD
PF05033--Pre-SET
PF00856--SET
|
| Gene Ontology |
GO:0005694--C:chromosome
GO:0005737--C:cytoplasm
GO:0005634--C:nucleus
GO:0003677--F:DNA binding
GO:0018024--F:histone-lysine N-methyltransferase activity
GO:0008270--F:zinc ion binding
GO:0010452--P:histone H3-K36 methylation
GO:0051567--P:histone H3-K9 methylation
GO:0051321--P:meiotic cell cycle
GO:0010629--P:negative regulation of gene expression
GO:0045835--P:negative regulation of meiotic nuclear division
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0040027--P:negative regulation of vulval development
GO:0040029--P:regulation of gene expression, epigenetic
GO:0007548--P:sex differentiation
GO:0006351--P:transcription, DNA-templated
GO:0072325--P:vulval cell fate commitment
|
| Orthology |
|
| Created Date |
25-Jun-2016 |
