| Tag |
Content |
| WERAM ID |
WERAM-Drm-0015 |
| Ensembl Protein ID |
FBpp0082389 |
| Uniprot Accession |
Q9VFK6; KMT5A_DROME; Q53ZQ8
|
| Genbank Protein ID |
NP_001247100.1; NP_650354.1; NP_731900.1
|
| Protein Name |
Histone-lysine N-methyltransferase pr-set7 |
| Genbank Nucleotide ID |
NM_001260171.2; NM_142097.4; NM_169577.3
|
| Gene Name |
PR-SET7;KMT5A;CG3307 |
| Ensembl Information |
|
| Details |
| Type |
Family |
Domain |
Substrates |
AA |
References (PMIDs) |
| HMT |
HMT_other |
SET |
H4K20me1 |
K |
20236312
|
|
| Status |
Reviewed |
| Classification |
| Type |
Family |
E-value |
Score |
Start |
End |
| HMT |
HMT_other |
0 |
1223 |
|
|
| HMT |
HMT_other |
7.00e-51 |
200 |
|
|
| HMT |
SET1 |
3.30e-27 |
95.5 |
563 |
675 |
|
| Organism |
Drosophila melanogaster |
| NCBI Taxa ID |
7227 |
Functional Description
(View)Functional Description
Histone methyltransferase that specifically monomethylates 'Lys-20' of histone H4. H4 'Lys-20' monomethylation is enriched during mitosis and represents a specific tag for epigenetic transcriptional repression. Mainly functions in euchromatin regions, thereby playing a central role in the silencing of euchromatic genes. Required for cell proliferation, possibly by contributing to the maintenance of proper higher-order structure of DNA and chromosome condensation during mitosis. |
Histone methyltransferase that specifically monomethylates 'Lys-20' of histone H4. H4 'Lys-20' monomethylation is enriched during mitosis and represents a specific tag for epigenetic transcriptional repression. Mainly functions in euchromatin regions, thereby playing a central role in the silencing of euchromatic genes. Required for cell proliferation, possibly by contributing to the maintenance of proper higher-order structure of DNA and chromosome condensation during mitosis.
|
| Domain Profile |
HMT HMT_other
Query: 1 MIMVRRRQRPAKEXXXXXXXXXXXXXXIPVDQALPLNVAGNLLEDQYFASPKRKDCRLMK 60
MIMVRRRQRPAKE IPVDQALPLNVAGNLLEDQYFASPKRKDCRLMK
Sbjct: 1 MIMVRRRQRPAKEAASSSSGGASSGSGIPVDQALPLNVAGNLLEDQYFASPKRKDCRLMK 60
Query: 61 VTQNGQLPEATMMAHNKDNKAGRTIGVPLATRSQTRTIENFFKANAAAKDSQKTIHTEEQ 120
VTQNGQLPEATMMAHNKDNKAGRTIGVPLATRSQTRTIENFFKANAAAKDSQKTIHTEEQ
Sbjct: 61 VTQNGQLPEATMMAHNKDNKAGRTIGVPLATRSQTRTIENFFKANAAAKDSQKTIHTEEQ 120
Query: 121 LNLGNQELKLDDEELNGQIKLDDEVLKLADKQINENLPFADEVDAKAEQKLMDXXXXXXX 180
LNLGNQELKLDDEELNGQIKLDDEVLKLADKQINENLPFADEVDAKAEQKLMD
Sbjct: 121 LNLGNQELKLDDEELNGQIKLDDEVLKLADKQINENLPFADEVDAKAEQKLMDEELQQVV 180
Query: 181 XXXXFDGSSRASSNSPFYQHDMDVMQEIQQTPEIPHIKKVTEPLEGLGSLADFQTHRSAL 240
FDGSSRASSNSPFYQHDMDVMQEIQQTPEIPHIKKVTEPLEGLGSLADFQTHRSAL
Sbjct: 181 EELLFDGSSRASSNSPFYQHDMDVMQEIQQTPEIPHIKKVTEPLEGLGSLADFQTHRSAL 240
Query: 241 RXXXXXXXXXXXXNIFLQEPVLTLDIDRTPTKASSIKINRSFELAGAVFSSPPSVLNACL 300
R NIFLQEPVLTLDIDRTPTKASSIKINRSFELAGAVFSSPPSVLNACL
Sbjct: 241 RDSHSSTHSSSTDNIFLQEPVLTLDIDRTPTKASSIKINRSFELAGAVFSSPPSVLNACL 300
Query: 301 NGRFNQIVSLNGQKEALDLPHFDLDQHDSSSCDSGVACGLTANTESPAGQPRRRKPATPH 360
NGRFNQIVSLNGQKEALDLPHFDLDQHDSSSCDSGVACGLTANTESPAGQPRRRKPATPH
Sbjct: 301 NGRFNQIVSLNGQKEALDLPHFDLDQHDSSSCDSGVACGLTANTESPAGQPRRRKPATPH 360
Query: 361 RILCPSPIKTALKVTGGICKVGSADPLSPRKSPRKLPTTTAAVAACKSRRRLNQPKPQAP 420
RILCPSPIKTALKVTGGICKVGSADPLSPRKSPRKLPTTTAAVAACKSRRRLNQPKPQAP
Sbjct: 361 RILCPSPIKTALKVTGGICKVGSADPLSPRKSPRKLPTTTAAVAACKSRRRLNQPKPQAP 420
Query: 421 YQPQLQKPPSXXXXXXXXXXXXXXXXXXXXXXXXXXXRALIKAAEERENQNKAPATANSN 480
YQPQLQKPPS RALIKAAEERENQNKAPATANSN
Sbjct: 421 YQPQLQKPPSQQQQQQQDDIVVVLDDDDDEGDDEDDVRALIKAAEERENQNKAPATANSN 480
Query: 481 KAGMKTMLKPAXXXXXXXXXXXXXXQPPLPLAATNGNREMTDFFPVRRSVRKTKTAVKEE 540
KAGMKTMLKPA QPPLPLAATNGNREMTDFFPVRRSVRKTKTAVKEE
Sbjct: 481 KAGMKTMLKPAPVKSKTKSKGPTKGQPPLPLAATNGNREMTDFFPVRRSVRKTKTAVKEE 540
Query: 541 WMRGLEQAVLEERCDGLQVRHFMGKGRGVVADRPFKRNEFVVEYVGDLISIGEAAEREKR 600
WMRGLEQAVLEERCDGLQVRHFMGKGRGVVADRPFKRNEFVVEYVGDLISIGEAAEREKR
Sbjct: 541 WMRGLEQAVLEERCDGLQVRHFMGKGRGVVADRPFKRNEFVVEYVGDLISIGEAAEREKR 600
Query: 601 YALDENAGCYMYYFKHKSQQYCIDATVDTGKLGRLINHSRAGNLMTKVVLIKQRPHLVLL 660
YALDENAGCYMYYFKHKSQQYCIDATVDTGKLGRLINHSRAGNLMTKVVLIKQRPHLVLL
Sbjct: 601 YALDENAGCYMYYFKHKSQQYCIDATVDTGKLGRLINHSRAGNLMTKVVLIKQRPHLVLL 660
Query: 661 AKDDIEPGEELTYDYGDRSKESLLHHPWLAF 691
AKDDIEPGEELTYDYGDRSKESLLHHPWLAF
Sbjct: 661 AKDDIEPGEELTYDYGDRSKESLLHHPWLAF 691
HMT HMT_other
Query: 514 TNGNREMTDFFPVRRSVRKTKTAVKEEWMRGLEQAVLEERCDGLQVRHFMGKGRGVVADR 573
T NR++TDF+PVRRS RK+K ++ E + +++ + + +G+++ GKGRGV+A +
Sbjct: 175 TQQNRKLTDFYPVRRSSRKSKAELQSEERKRIDELIESGKEEGMKIDLIDGKGRGVIATK 234
Query: 574 PFKRNEFVVEYVGDLISIGEAAEREKRYALDENAGCYMYYFKHKSQQYCIDATVDTGKLG 633
F R +FVVEY GDLI I +A +RE YA D + GCYMYYF++ S+ YC+DAT +T +LG
Sbjct: 235 QFSRGDFVVEYHGDLIEITDAKKREALYAQDPSTGCYMYYFQYLSKTYCVDATRETNRLG 294
Query: 634 RLINHSRAGNLMTKVVLIKQRPHLVLLAKDDIEPGEELTYDYGDRSKESLLHHPWL 689
RLINHS+ GN TK+ I PHL+L+A DI GEEL YDYGDRSK S+ HPWL
Sbjct: 295 RLINHSKCGNCQTKLHDIDGVPHLILIASRDIAAGEELLYDYGDRSKASIEAHPWL 350
HMT SET1
SET1.txt 9 kikglglvakkeiekeelviEYvGevirsevadkrekeyekkeig.vylfrldedae.vvvdatk.kgniarfinhscepNceakvvavdgekkiviy 103
kg+g+va+++++ +e+v+EYvG++i+ +a +rek+y +e +y++ ++++++ +++dat +g r+inhs + N+ +kvv ++++ ++v+
FBpp0082389 563 MGKGRGVVADRPFKRNEFVVEYVGDLISIGEAAEREKRYALDENAgCYMYYFKHKSQqYCIDATVdTGKLGRLINHSRAGNLMTKVVLIKQRPHLVLL 660
5689**********************************99877666****99998666*****9627889**************************** PP
SET1.txt 104 akraIekgeeltydY 118
ak +Ie geeltydY
FBpp0082389 661 AKDDIEPGEELTYDY 675
*************** PP
|
Protein Sequence
(Fasta) | MIMVRRRQRP AKEAASSSSG GASSGSGIPV DQALPLNVAG NLLEDQYFAS PKRKDCRLMK 60
VTQNGQLPEA TMMAHNKDNK AGRTIGVPLA TRSQTRTIEN FFKANAAAKD SQKTIHTEEQ 120
LNLGNQELKL DDEELNGQIK LDDEVLKLAD KQINENLPFA DEVDAKAEQK LMDEELQQVV 180
EELLFDGSSR ASSNSPFYQH DMDVMQEIQQ TPEIPHIKKV TEPLEGLGSL ADFQTHRSAL 240
RDSHSSTHSS STDNIFLQEP VLTLDIDRTP TKASSIKINR SFELAGAVFS SPPSVLNACL 300
NGRFNQIVSL NGQKEALDLP HFDLDQHDSS SCDSGVACGL TANTESPAGQ PRRRKPATPH 360
RILCPSPIKT ALKVTGGICK VGSADPLSPR KSPRKLPTTT AAVAACKSRR RLNQPKPQAP 420
YQPQLQKPPS QQQQQQQDDI VVVLDDDDDE GDDEDDVRAL IKAAEERENQ NKAPATANSN 480
KAGMKTMLKP APVKSKTKSK GPTKGQPPLP LAATNGNREM TDFFPVRRSV RKTKTAVKEE 540
WMRGLEQAVL EERCDGLQVR HFMGKGRGVV ADRPFKRNEF VVEYVGDLIS IGEAAEREKR 600
YALDENAGCY MYYFKHKSQQ YCIDATVDTG KLGRLINHSR AGNLMTKVVL IKQRPHLVLL 660
AKDDIEPGEE LTYDYGDRSK ESLLHHPWLA F 691Protein Fasta Sequence
>FBpp0082389|PR-SET7;KMT5A;CG3307|Drosophila melanogaster
MIMVRRRQRPAKEAASSSSGGASSGSGIPVDQALPLNVAGNLLEDQYFASPKRKDCRLMKVTQNGQLPEATMMAHNKDNKAGRTIGVPLATRSQTRTIENFFKANAAAKDSQKTIHTEEQLNLGNQELKLDDEELNGQIKLDDEVLKLADKQINENLPFADEVDAKAEQKLMDEELQQVVEELLFDGSSRASSNSPFYQHDMDVMQEIQQTPEIPHIKKVTEPLEGLGSLADFQTHRSALRDSHSSTHSSSTDNIFLQEPVLTLDIDRTPTKASSIKINRSFELAGAVFSSPPSVLNACLNGRFNQIVSLNGQKEALDLPHFDLDQHDSSSCDSGVACGLTANTESPAGQPRRRKPATPHRILCPSPIKTALKVTGGICKVGSADPLSPRKSPRKLPTTTAAVAACKSRRRLNQPKPQAPYQPQLQKPPSQQQQQQQDDIVVVLDDDDDEGDDEDDVRALIKAAEERENQNKAPATANSNKAGMKTMLKPAPVKSKTKSKGPTKGQPPLPLAATNGNREMTDFFPVRRSVRKTKTAVKEEWMRGLEQAVLEERCDGLQVRHFMGKGRGVVADRPFKRNEFVVEYVGDLISIGEAAEREKRYALDENAGCYMYYFKHKSQQYCIDATVDTGKLGRLINHSRAGNLMTKVVLIKQRPHLVLLAKDDIEPGEELTYDYGDRSKESLLHHPWLAF |
Nucleotide Sequence
(Fasta) | TGCGCAATCT GGTAACACTA ACCGACGCAA AAAAGAAAGA ACCAAAAAAG TTTGCGGAAA 60
AGTGCAACAA TTAATTTCCC CCGCCATTGA AATGCTGCCA TGCATAAAGT CGATCGCATC 120
CGTTTAAAAA TGCGCTTCTG CGTATGACGA CAGTTTTCCG AGCGAGTGGC GAAAACTGTA 180
CGCAAGAGGG GCGAGTAGAG GAGAAAAGTG CATGGCAGAG AGCGAGAGTA AGAGAGGTAA 240
TTGCAGTTTG GTTTTTCCGC GTGTGCGTGT GAGAGGTAAA ACGCGTGTCC AGAAAAAAAC 300
GCGCCAACGC CAAAAAAAAA CCCAAGTAAC TACCGCCCAC ACAGCGATCA CGCGCCCCCA 360
ACCCATTTTA AATGATAATG GTGCGAAGAC GACAACGGCC CGCCAAGGAA GCCGCATCCT 420
CATCCTCTGG TGGAGCTTCC TCGGGATCGG GAATTCCTGT TGACCAGGCA CTGCCACTGA 480
ATGTGGCGGG AAATCTGCTG GAGGATCAGT ATTTTGCCAG CCCCAAGCGG AAAGACTGCC 540
GTTTGATGAA GGTCACTCAA AATGGCCAAC TGCCGGAAGC CACAATGATG GCACACAACA 600
AAGACAACAA AGCGGGTCGC ACAATAGGAG TTCCCTTGGC CACGCGCTCA CAAACTCGCA 660
CCATTGAGAA CTTCTTCAAA GCCAATGCTG CCGCTAAGGA TTCCCAAAAG ACAATACACA 720
CAGAGGAGCA GTTGAATCTA GGAAATCAGG AACTGAAACT GGACGATGAG GAGCTAAATG 780
GACAGATAAA ACTAGATGAC GAGGTGCTAA AGCTGGCAGA CAAGCAGATA AATGAAAACC 840
TTCCCTTTGC CGACGAAGTA GATGCCAAGG CAGAACAAAA GCTTATGGAT GAGGAACTGC 900
AGCAGGTGGT GGAGGAACTT CTGTTCGATG GCAGTTCCAG AGCGTCCTCC AATTCGCCCT 960
TTTATCAGCA TGATATGGAT GTCATGCAGG AGATCCAGCA GACTCCAGAA ATTCCACACA 1020
TCAAAAAGGT CACAGAGCCG CTCGAGGGAC TGGGCTCTCT GGCCGACTTC CAGACACATC 1080
GCTCTGCGCT GAGGGACAGC CACAGTTCCA CGCACAGCAG CAGCACCGAC AACATCTTCC 1140
TGCAGGAGCC GGTACTGACC CTGGACATTG ATCGCACGCC CACCAAAGCC TCCAGCATAA 1200
AGATCAATCG GAGCTTCGAA CTGGCCGGAG CCGTATTCTC ATCACCTCCG TCGGTGCTAA 1260
ACGCCTGTCT CAATGGACGC TTCAATCAAA TAGTAAGCCT GAATGGACAA AAGGAGGCGC 1320
TGGACTTGCC GCACTTCGAT TTGGATCAAC ATGACAGTAG TTCTTGCGAC AGCGGAGTAG 1380
CCTGTGGTCT CACTGCCAAT ACAGAATCGC CAGCGGGGCA ACCCCGACGC AGAAAACCAG 1440
CCACACCGCA TCGCATCCTC TGCCCCTCGC CAATCAAAAC GGCTTTGAAG GTAACTGGAG 1500
GGATTTGCAA GGTCGGATCT GCGGATCCAT TGTCGCCGCG CAAGTCTCCT CGAAAACTGC 1560
CGACCACAAC AGCAGCGGTG GCAGCCTGCA AGTCGCGTCG AAGACTGAAC CAGCCAAAGC 1620
CACAAGCGCC TTACCAGCCA CAGCTACAGA AACCACCGTC ACAACAGCAG CAGCAGCAGC 1680
AGGATGATAT CGTCGTGGTG CTAGACGACG ACGATGATGA AGGAGATGAC GAGGACGACG 1740
TTCGAGCCCT GATCAAGGCT GCCGAGGAGC GTGAAAACCA GAACAAAGCA CCAGCCACAG 1800
CGAACAGCAA CAAAGCAGGC ATGAAAACGA TGCTCAAGCC TGCGCCCGTG AAATCAAAGA 1860
CCAAAAGCAA GGGGCCAACG AAGGGACAAC CGCCGCTGCC CTTGGCTGCC ACCAACGGCA 1920
ATCGTGAGAT GACGGACTTC TTCCCGGTGC GAAGGAGTGT GCGCAAGACT AAGACGGCCG 1980
TCAAGGAGGA ATGGATGCGA GGCTTGGAGC AAGCAGTGCT GGAAGAGCGC TGCGATGGTC 2040
TCCAAGTACG CCACTTTATG GGCAAGGGAA GAGGCGTAGT CGCCGATCGG CCCTTTAAAC 2100
GCAACGAATT TGTGGTTGAG TATGTGGGAG ATCTCATATC TATAGGCGAA GCCGCGGAAC 2160
GGGAGAAACG CTATGCGTTG GACGAGAATG CTGGGTGCTA TATGTACTAC TTCAAGCACA 2220
AGTCCCAGCA GTACTGCATC GATGCAACCG TTGACACCGG CAAGCTGGGG CGCCTCATCA 2280
ATCACTCGCG GGCTGGTAAC CTAATGACCA AAGTAGTACT TATCAAACAG CGGCCGCATC 2340
TCGTACTCCT GGCCAAGGAC GACATCGAGC CGGGCGAGGA ACTGACCTAT GACTACGGGG 2400
ACCGATCGAA GGAGTCACTA TTGCACCATC CTTGGTTGGC CTTCTGAGGA AGAGCTCTCC 2460
AGGAGCTCGC GAAAGGGGTT GCGGTACAGC CTTAAAACGA AGACTATTTA CCATGTTCAG 2520
GGCAGAGAAT CTTTAAAATA ATAAGACCTG GGCTAAACTG GTTTTTGGCT CGAGGGAATC 2580
TTTCTTAGCT TTTATACGTA GATTGCCTTG CCTTGAACCA CTGCAAAATT GTTTTCAGAC 2640
CTGTTTCCGT GTGATAAGTT GCCGGAATTT GATTCATTTA CAAAGTTTCA TTAAGCAAAA 2700
TTATATCAAT ATTGCAAGCA CTTATATTTT TGGTAAGACC AATTCAATCA TTACGAATTC 2760
CGGCAATTTG GATCGGAATG GAGAGAGGCG TATTTGACAC CGGTTCTGGG CAGCCCCGAG 2820
CTTAGATCTT ATTTGAGGAA AAGTATATAA ACTGTTAGTT CAAAATATCA TAACGGATAG 2880
CGAAACCCAC ACGCCCCACA CCCAAGGGTG GTTCCAGCCA GGGACGAAAA GTAATCAATG 2940
TAAATTCTAA CAAGTTTGCC TCAGAAATAG GTCTAATGTC AATTTCGATC TTCGGCGTTA 3000
CCAAAATAAG TTACAAATGA AGTTAATATT TCCCTTTGGG TCAGTGAAAT AATCGAAATT 3060
ATCAATTAAG AACAAATTTA TCAAAAAGAC CTAGACTATA CAGATTGTAA ATTGATATTA 3120
GACCCATGAT CCCCAAAGCA AAATGCCTTT AAATTGTACG ATTACGATTC AATCCCTATA 3180
AGACTCATTA TCGATCCACC CGTGATCCAA GCAACCCCCC CCTCCCCCTC CCTCCTTACA 3240
CAAACTCATG AGCATCTTTT TGGATTTGTT AGCGTTTCAT TATGTTTAGA GCAAGGCTAA 3300
AGTTAAGGAG AGATAATAAT GATAATAATA ATAATAAAAA CAACGCGCTT AAGCATTAAG 3360
GCATCTTAAG ATAATTGAAT GAAATCGAAA AACTGTTGAC CATTTGAAAA GAGATGATGA 3420
TGTTGATGAA GCCACGCATT CACATTGACA AGAATCGATT GTACACTATT TATATAGATA 3480
TTTATATTAG ATACATGTGT AATTTCTAAC TATTACGTAC TATTTACTGC CATAGAGCTA 3540
TACACTCCCC CTCGCACCTG TCCCAAAAAA AAAAAAAAAA CCCCTAGGAA CTGACACTAC 3600
TGAATTGTTG ATTTAACCCA TTGACACACT CATTAATTCT CGAGGCTTCT CCAGGAGAGT 3660
AGTGGCCTGC TGGACACCTA GTGCTTCGAC TTACTGATAA TCTCTCTACT TACACGCAGG 3720
TTTCAATCAC ACACTCAAGC AATTAAATGA TAAATCACCC CGCCCCTGCC CCCGAAAATA 3780
CGGCATCGTT AGTTAATCGA CTTAGTTCAA ATTTGTGTTG TCCCATTTGA ACCAGATTTC 3840
TGTATTTTAA ATGAATGCTC CAATATATTG AAGGATTTTG TTTTTTTAAA TAGGTTTATT 3900
TTAATCAGCG CATATCTTTT AATTATACAA TATGGTAAAT ATATTTTAAT ACGTTCTAGT 3960
ACATAGGTAA TTCATTTATT TAAAACCAAG CAGCAACCAT CTATAATCAT GTTCTTGTTT 4020
TTACCTTTTT TTTTCATTGA CTTGGCAAAA TGAAACAAAA CAAATTGAAA TCTATTTGTA 4080
ATTTACATTT AAGCCTAAAA ACATATGATT ACATCAAACA CTTAGTTTTA GTCGATAATT 4140
GTTTATAATT TTTCAGACAC ACACACACAC AGACACATTC AAC
4184Nucleotide Fasta Sequence
>FBpp0082389|SET1|Drosophila melanogaster
TGCGCAATCTGGTAACACTAACCGACGCAAAAAAGAAAGAACCAAAAAAGTTTGCGGAAAAGTGCAACAATTAATTTCCCCCGCCATTGAAATGCTGCCATGCATAAAGTCGATCGCATCCGTTTAAAAATGCGCTTCTGCGTATGACGACAGTTTTCCGAGCGAGTGGCGAAAACTGTACGCAAGAGGGGCGAGTAGAGGAGAAAAGTGCATGGCAGAGAGCGAGAGTAAGAGAGGTAATTGCAGTTTGGTTTTTCCGCGTGTGCGTGTGAGAGGTAAAACGCGTGTCCAGAAAAAAACGCGCCAACGCCAAAAAAAAACCCAAGTAACTACCGCCCACACAGCGATCACGCGCCCCCAACCCATTTTAAATGATAATGGTGCGAAGACGACAACGGCCCGCCAAGGAAGCCGCATCCTCATCCTCTGGTGGAGCTTCCTCGGGATCGGGAATTCCTGTTGACCAGGCACTGCCACTGAATGTGGCGGGAAATCTGCTGGAGGATCAGTATTTTGCCAGCCCCAAGCGGAAAGACTGCCGTTTGATGAAGGTCACTCAAAATGGCCAACTGCCGGAAGCCACAATGATGGCACACAACAAAGACAACAAAGCGGGTCGCACAATAGGAGTTCCCTTGGCCACGCGCTCACAAACTCGCACCATTGAGAACTTCTTCAAAGCCAATGCTGCCGCTAAGGATTCCCAAAAGACAATACACACAGAGGAGCAGTTGAATCTAGGAAATCAGGAACTGAAACTGGACGATGAGGAGCTAAATGGACAGATAAAACTAGATGACGAGGTGCTAAAGCTGGCAGACAAGCAGATAAATGAAAACCTTCCCTTTGCCGACGAAGTAGATGCCAAGGCAGAACAAAAGCTTATGGATGAGGAACTGCAGCAGGTGGTGGAGGAACTTCTGTTCGATGGCAGTTCCAGAGCGTCCTCCAATTCGCCCTTTTATCAGCATGATATGGATGTCATGCAGGAGATCCAGCAGACTCCAGAAATTCCACACATCAAAAAGGTCACAGAGCCGCTCGAGGGACTGGGCTCTCTGGCCGACTTCCAGACACATCGCTCTGCGCTGAGGGACAGCCACAGTTCCACGCACAGCAGCAGCACCGACAACATCTTCCTGCAGGAGCCGGTACTGACCCTGGACATTGATCGCACGCCCACCAAAGCCTCCAGCATAAAGATCAATCGGAGCTTCGAACTGGCCGGAGCCGTATTCTCATCACCTCCGTCGGTGCTAAACGCCTGTCTCAATGGACGCTTCAATCAAATAGTAAGCCTGAATGGACAAAAGGAGGCGCTGGACTTGCCGCACTTCGATTTGGATCAACATGACAGTAGTTCTTGCGACAGCGGAGTAGCCTGTGGTCTCACTGCCAATACAGAATCGCCAGCGGGGCAACCCCGACGCAGAAAACCAGCCACACCGCATCGCATCCTCTGCCCCTCGCCAATCAAAACGGCTTTGAAGGTAACTGGAGGGATTTGCAAGGTCGGATCTGCGGATCCATTGTCGCCGCGCAAGTCTCCTCGAAAACTGCCGACCACAACAGCAGCGGTGGCAGCCTGCAAGTCGCGTCGAAGACTGAACCAGCCAAAGCCACAAGCGCCTTACCAGCCACAGCTACAGAAACCACCGTCACAACAGCAGCAGCAGCAGCAGGATGATATCGTCGTGGTGCTAGACGACGACGATGATGAAGGAGATGACGAGGACGACGTTCGAGCCCTGATCAAGGCTGCCGAGGAGCGTGAAAACCAGAACAAAGCACCAGCCACAGCGAACAGCAACAAAGCAGGCATGAAAACGATGCTCAAGCCTGCGCCCGTGAAATCAAAGACCAAAAGCAAGGGGCCAACGAAGGGACAACCGCCGCTGCCCTTGGCTGCCACCAACGGCAATCGTGAGATGACGGACTTCTTCCCGGTGCGAAGGAGTGTGCGCAAGACTAAGACGGCCGTCAAGGAGGAATGGATGCGAGGCTTGGAGCAAGCAGTGCTGGAAGAGCGCTGCGATGGTCTCCAAGTACGCCACTTTATGGGCAAGGGAAGAGGCGTAGTCGCCGATCGGCCCTTTAAACGCAACGAATTTGTGGTTGAGTATGTGGGAGATCTCATATCTATAGGCGAAGCCGCGGAACGGGAGAAACGCTATGCGTTGGACGAGAATGCTGGGTGCTATATGTACTACTTCAAGCACAAGTCCCAGCAGTACTGCATCGATGCAACCGTTGACACCGGCAAGCTGGGGCGCCTCATCAATCACTCGCGGGCTGGTAACCTAATGACCAAAGTAGTACTTATCAAACAGCGGCCGCATCTCGTACTCCTGGCCAAGGACGACATCGAGCCGGGCGAGGAACTGACCTATGACTACGGGGACCGATCGAAGGAGTCACTATTGCACCATCCTTGGTTGGCCTTCTGAGGAAGAGCTCTCCAGGAGCTCGCGAAAGGGGTTGCGGTACAGCCTTAAAACGAAGACTATTTACCATGTTCAGGGCAGAGAATCTTTAAAATAATAAGACCTGGGCTAAACTGGTTTTTGGCTCGAGGGAATCTTTCTTAGCTTTTATACGTAGATTGCCTTGCCTTGAACCACTGCAAAATTGTTTTCAGACCTGTTTCCGTGTGATAAGTTGCCGGAATTTGATTCATTTACAAAGTTTCATTAAGCAAAATTATATCAATATTGCAAGCACTTATATTTTTGGTAAGACCAATTCAATCATTACGAATTCCGGCAATTTGGATCGGAATGGAGAGAGGCGTATTTGACACCGGTTCTGGGCAGCCCCGAGCTTAGATCTTATTTGAGGAAAAGTATATAAACTGTTAGTTCAAAATATCATAACGGATAGCGAAACCCACACGCCCCACACCCAAGGGTGGTTCCAGCCAGGGACGAAAAGTAATCAATGTAAATTCTAACAAGTTTGCCTCAGAAATAGGTCTAATGTCAATTTCGATCTTCGGCGTTACCAAAATAAGTTACAAATGAAGTTAATATTTCCCTTTGGGTCAGTGAAATAATCGAAATTATCAATTAAGAACAAATTTATCAAAAAGACCTAGACTATACAGATTGTAAATTGATATTAGACCCATGATCCCCAAAGCAAAATGCCTTTAAATTGTACGATTACGATTCAATCCCTATAAGACTCATTATCGATCCACCCGTGATCCAAGCAACCCCCCCCTCCCCCTCCCTCCTTACACAAACTCATGAGCATCTTTTTGGATTTGTTAGCGTTTCATTATGTTTAGAGCAAGGCTAAAGTTAAGGAGAGATAATAATGATAATAATAATAATAAAAACAACGCGCTTAAGCATTAAGGCATCTTAAGATAATTGAATGAAATCGAAAAACTGTTGACCATTTGAAAAGAGATGATGATGTTGATGAAGCCACGCATTCACATTGACAAGAATCGATTGTACACTATTTATATAGATATTTATATTAGATACATGTGTAATTTCTAACTATTACGTACTATTTACTGCCATAGAGCTATACACTCCCCCTCGCACCTGTCCCAAAAAAAAAAAAAAAACCCCTAGGAACTGACACTACTGAATTGTTGATTTAACCCATTGACACACTCATTAATTCTCGAGGCTTCTCCAGGAGAGTAGTGGCCTGCTGGACACCTAGTGCTTCGACTTACTGATAATCTCTCTACTTACACGCAGGTTTCAATCACACACTCAAGCAATTAAATGATAAATCACCCCGCCCCTGCCCCCGAAAATACGGCATCGTTAGTTAATCGACTTAGTTCAAATTTGTGTTGTCCCATTTGAACCAGATTTCTGTATTTTAAATGAATGCTCCAATATATTGAAGGATTTTGTTTTTTTAAATAGGTTTATTTTAATCAGCGCATATCTTTTAATTATACAATATGGTAAATATATTTTAATACGTTCTAGTACATAGGTAATTCATTTATTTAAAACCAAGCAGCAACCATCTATAATCATGTTCTTGTTTTTACCTTTTTTTTTCATTGACTTGGCAAAATGAAACAAAACAAATTGAAATCTATTTGTAATTTACATTTAAGCCTAAAAACATATGATTACATCAAACACTTAGTTTTAGTCGATAATTGTTTATAATTTTTCAGACACACACACACACAGACACATTCAAC
|
| Sequence Source |
Ensembl |
| Keyword |
KW-0131--Cell cycle
KW-0132--Cell division
KW-0156--Chromatin regulator
KW-0158--Chromosome
KW-0181--Complete proteome
KW-0489--Methyltransferase
KW-0498--Mitosis
KW-0539--Nucleus
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0678--Repressor
KW-0949--S-adenosyl-L-methionine
KW-0804--Transcription
KW-0805--Transcription regulation
KW-0808--Transferase
--
|
| Interpro |
IPR016858--Hist_H4-K20_MeTrfase
IPR001214--SET_dom
|
| PROSITE |
PS51571--SAM_MT43_PR_SET
PS50280--SET
|
| Pfam |
PF00856--SET
|
| Gene Ontology |
GO:0005634--C:nucleus
GO:0005700--C:polytene chromosome
GO:0042799--F:histone methyltransferase activity (H4-K20 specific)
GO:0051301--P:cell division
GO:0030261--P:chromosome condensation
GO:0000077--P:DNA damage checkpoint
GO:0034771--P:histone H4-K20 monomethylation
GO:0016571--P:histone methylation
GO:0007067--P:mitotic nuclear division
GO:0035067--P:negative regulation of histone acetylation
GO:0006355--P:regulation of transcription, DNA-templated
GO:0006351--P:transcription, DNA-templated
|
| Orthology |
|
| Created Date |
25-Jun-2016 |
