Tag |
Content |
WERAM ID |
WERAM-Cae-0020 |
Ensembl Protein ID |
T26A5.7a |
Uniprot Accession |
Q22795; SET1_CAEEL |
Genbank Protein ID |
NP_001022796.1 |
Protein Name |
Probable histone-lysine N-methyltransferase set-1 |
Genbank Nucleotide ID |
NM_001027625.3 |
Gene Name |
SET1 |
Ensembl Information |
|
Details |
Type |
Family |
Domain |
Substrates |
AA |
References (PMIDs) |
HMT |
SET1 |
SET |
H3K4 |
K |
20236312 |
|
Status |
Reviewed |
Classification |
Type |
Family |
E-value |
Score |
Start |
End |
HMT |
HMT_other |
1.00e-40 |
164 |
|
|
HMT |
SET1 |
2.50e-36 |
125 |
106 |
225 |
HMT |
HMT_other |
4.00e-36 |
148 |
|
|
|
Organism |
Caenorhabditis elegans |
NCBI Taxa ID |
6239 |
Functional Description (View)Functional Description
Probable histone methyltransferase involved in chromatin modification and/or regulation. |
Probable histone methyltransferase involved in chromatin modification and/or regulation.
|
Domain Profile |
HMT HMT_other
Query: 55 RKGVSVKDVSNHKITEFFQVRRSNRKTSKQISDEAKHALRDTVLKGTNERLLEVYKDVV- 113 RK K N K+T+F+ VRRS+RK+ ++ E + + D +++ E +++ D++ Sbjct: 168 RKKAQGKTQQNRKLTDFYPVRRSSRKSKAELQSEERKRI-DELIESGKEEGMKI--DLID 224 Query: 114 -KGRGIRTKVNFEKGDFVVEYRGVMMEYSEAKVIEEQYSNDEEIGSYMYFFEHNNKKWCI 172 KGRG+ F +GDFVVEY G ++E ++AK E Y+ D G YMY+F++ +K +C+ Sbjct: 225 GKGRGVIATKQFSRGDFVVEYHGDLIEITDAKKREALYAQDPSTGCYMYYFQYLSKTYCV 284 Query: 173 DATKESPWKGRLINHSVLRPNLKTKVVEIDGSHHLILVARRQIAQGEELLYDYGDRSAET 232 DAT+E+ GRLINHS N +TK+ +IDG HLIL+A R IA GEELLYDYGDRS + Sbjct: 285 DATRETNRLGRLINHSKCG-NCQTKLHDIDGVPHLILIASRDIAAGEELLYDYGDRSKAS 343 Query: 233 IAKNPWL 239 I +PWL Sbjct: 344 IEAHPWL 350
HMT SET1
SET1.txt 3 levakskikglglvakkeiekeelviEYvGevirsevadkrekeyekkeig.vylfrldedae.vvvdatkkgn.iarfinhsce.pNceakvvavdgekk 99 lev+k+ +kg+g+++k ++ek+++v+EY+G ++++++a+ e++y+++e + +y++ ++++++ +++datk++ + r+inhs+ pN+++kvv++dg+++ T26A5.7a 106 LEVYKDVVKGRGIRTKVNFEKGDFVVEYRGVMMEYSEAKVIEEQYSNDEEIgSYMYFFEHNNKkWCIDATKESPwKGRLINHSVLrPNLKTKVVEIDGSHH 206 899*******************************************998777****99998777*********9899******977*************** PP SET1.txt 100 iviyakraIekgeeltydY 118 ++++a+r+I++geel+ydY T26A5.7a 207 LILVARRQIAQGEELLYDY 225 ******************* PP
HMT HMT_other
Query: 65 NHKITEFFQVRRSNRKTSKQISDEAKHALRDTVLKGTNERL--LEVYKDVVKGRGIRTKV 122 N ++T+FF VRRS RKT + +E L VL+ ER L+V + KGRG+ Sbjct: 517 NREMTDFFPVRRSVRKTKTAVKEEWMRGLEQAVLE---ERCDGLQVRHFMGKGRGVVADR 573 Query: 123 NFEKGDFVVEYRGVMMEYSEAKVIEEQYSNDEEIGSYMYFFEHNNKKWCIDATKESPWKG 182 F++ +FVVEY G ++ EA E++Y+ DE G YMY+F+H ++++CIDAT ++ G Sbjct: 574 PFKRNEFVVEYVGDLISIGEAAEREKRYALDENAGCYMYYFKHKSQQYCIDATVDTGKLG 633 Query: 183 RLINHSVLRPNLKTKVVEIDGSHHLILVARRQIAQGEELLYDYGDRSAETIAKNPWLV 240 RLINHS NL TKVV I HL+L+A+ I GEEL YDYGDRS E++ +PWL Sbjct: 634 RLINHSRAG-NLMTKVVLIKQRPHLVLLAKDDIEPGEELTYDYGDRSKESLLHHPWLA 690
|
Protein Sequence (Fasta) | MKVAAKKLAT SRMRKDRAAA ASPSSDIENS ENPSSLASHS SSSGRMTPSK NTRSRKGVSV 60 KDVSNHKITE FFQVRRSNRK TSKQISDEAK HALRDTVLKG TNERLLEVYK DVVKGRGIRT 120 KVNFEKGDFV VEYRGVMMEY SEAKVIEEQY SNDEEIGSYM YFFEHNNKKW CIDATKESPW 180 KGRLINHSVL RPNLKTKVVE IDGSHHLILV ARRQIAQGEE LLYDYGDRSA ETIAKNPWLV 240 NT 242Protein Fasta Sequence
>T26A5.7a|SET1|Caenorhabditis elegans MKVAAKKLATSRMRKDRAAAASPSSDIENSENPSSLASHSSSSGRMTPSKNTRSRKGVSVKDVSNHKITEFFQVRRSNRKTSKQISDEAKHALRDTVLKGTNERLLEVYKDVVKGRGIRTKVNFEKGDFVVEYRGVMMEYSEAKVIEEQYSNDEEIGSYMYFFEHNNKKWCIDATKESPWKGRLINHSVLRPNLKTKVVEIDGSHHLILVARRQIAQGEELLYDYGDRSAETIAKNPWLVNT
|
Nucleotide Sequence (Fasta) | CGGTGTCACT CGAAGGATGA AAGTTGCCGC GAAGAAGCTG GCAACGAGTA GAATGCGAAA 60 GGATCGTGCC GCAGCAGCGT CACCATCTAG TGATATTGAG AACTCCGAAA ATCCATCGTC 120 TTTGGCTTCA CACTCTTCAT CTTCAGGAAG AATGACACCG TCGAAAAACA CAAGGAGCAG 180 AAAAGGAGTG TCGGTGAAAG ATGTCTCAAA CCATAAAATC ACAGAATTCT TCCAAGTGCG 240 GCGAAGTAAT CGGAAGACGA GCAAGCAAAT TAGCGATGAA GCTAAACATG CTCTTCGCGA 300 TACCGTACTC AAGGGGACTA ATGAACGACT TCTTGAAGTG TACAAAGATG TTGTGAAGGG 360 GCGAGGAATT CGAACGAAAG TTAACTTTGA AAAAGGAGAC TTTGTTGTCG AATACAGAGG 420 TGTTATGATG GAGTACTCGG AAGCAAAAGT GATAGAAGAA CAATATTCGA ATGATGAGGA 480 AATCGGATCC TACATGTACT TTTTTGAGCA CAACAATAAA AAATGGTGTA TCGATGCGAC 540 AAAAGAATCT CCATGGAAAG GACGACTCAT CAATCATTCC GTGTTAAGGC CGAATCTCAA 600 AACGAAAGTG GTGGAAATCG ATGGGTCGCA TCACCTGATT CTCGTCGCCA GGCGTCAAAT 660 CGCACAAGGA GAAGAGCTTC TCTACGATTA TGGAGATCGT TCAGCAGAGA CGATTGCCAA 720 GAATCCATGG CTTGTGAACA CATAATATGT TGCTCCACAA CATCTCTTCG ATCTGCTCAA 780 TCCATTTCAA ATGTTCATTT ACCTTCACGA GTATACTACT GTAATTCCCT TCATTTTCTC 840 ATATTTTCCA CGGCACTCGT GCCCAATCCT CTCATTACTT CGTCTCTTTC AACCGCCTTT 900 TCTCATTCTC ACAGCGAATC AAACCTGAAA CAAATCTCAA TAACGAGCCG TAATAACGTG 960 CTCATTTATG ATAATCTGGA TCTCGTGAGT ATCCAATTCT GTACCTTTCC TGTTGACTTT 1020 TGAAAAGTCC CTTGTTCTTT CCTTTCATTG AAACCTGAAA ATCTCCTCAC TTGTTCCACT 1080 ACGAAATGCC TTTAATATCT TTAATTCTTC TGTAAATTTC TCGTTGATCG CCCATTTTTT 1140 CCTGAATTAT TCATTTTTGT GGTGTACATG AGGTGCGAGT TGGAAACCTA CTTTAATGAC 1200 TGGTTAACGC TAAAATCGTT TCCATCCCTA TCGGAAAACA TTATCAGCGT GCAAATCTCA 1260 ATTTTTCATT TTGAAAACAA TTAAAATCCA T
1292Nucleotide Fasta Sequence
>T26A5.7a|HMT_other|Caenorhabditis elegans CGGTGTCACTCGAAGGATGAAAGTTGCCGCGAAGAAGCTGGCAACGAGTAGAATGCGAAAGGATCGTGCCGCAGCAGCGTCACCATCTAGTGATATTGAGAACTCCGAAAATCCATCGTCTTTGGCTTCACACTCTTCATCTTCAGGAAGAATGACACCGTCGAAAAACACAAGGAGCAGAAAAGGAGTGTCGGTGAAAGATGTCTCAAACCATAAAATCACAGAATTCTTCCAAGTGCGGCGAAGTAATCGGAAGACGAGCAAGCAAATTAGCGATGAAGCTAAACATGCTCTTCGCGATACCGTACTCAAGGGGACTAATGAACGACTTCTTGAAGTGTACAAAGATGTTGTGAAGGGGCGAGGAATTCGAACGAAAGTTAACTTTGAAAAAGGAGACTTTGTTGTCGAATACAGAGGTGTTATGATGGAGTACTCGGAAGCAAAAGTGATAGAAGAACAATATTCGAATGATGAGGAAATCGGATCCTACATGTACTTTTTTGAGCACAACAATAAAAAATGGTGTATCGATGCGACAAAAGAATCTCCATGGAAAGGACGACTCATCAATCATTCCGTGTTAAGGCCGAATCTCAAAACGAAAGTGGTGGAAATCGATGGGTCGCATCACCTGATTCTCGTCGCCAGGCGTCAAATCGCACAAGGAGAAGAGCTTCTCTACGATTATGGAGATCGTTCAGCAGAGACGATTGCCAAGAATCCATGGCTTGTGAACACATAATATGTTGCTCCACAACATCTCTTCGATCTGCTCAATCCATTTCAAATGTTCATTTACCTTCACGAGTATACTACTGTAATTCCCTTCATTTTCTCATATTTTCCACGGCACTCGTGCCCAATCCTCTCATTACTTCGTCTCTTTCAACCGCCTTTTCTCATTCTCACAGCGAATCAAACCTGAAACAAATCTCAATAACGAGCCGTAATAACGTGCTCATTTATGATAATCTGGATCTCGTGAGTATCCAATTCTGTACCTTTCCTGTTGACTTTTGAAAAGTCCCTTGTTCTTTCCTTTCATTGAAACCTGAAAATCTCCTCACTTGTTCCACTACGAAATGCCTTTAATATCTTTAATTCTTCTGTAAATTTCTCGTTGATCGCCCATTTTTTCCTGAATTATTCATTTTTGTGGTGTACATGAGGTGCGAGTTGGAAACCTACTTTAATGACTGGTTAACGCTAAAATCGTTTCCATCCCTATCGGAAAACATTATCAGCGTGCAAATCTCAATTTTTCATTTTGAAAACAATTAAAATCCAT
|
Sequence Source |
Ensembl |
Keyword |
KW-0156--Chromatin regulator KW-0181--Complete proteome KW-0489--Methyltransferase KW-0539--Nucleus KW-1185--Reference proteome KW-0949--S-adenosyl-L-methionine KW-0804--Transcription KW-0805--Transcription regulation KW-0808--Transferase --
|
Interpro |
IPR016858--Hist_H4-K20_MeTrfase IPR001214--SET_dom
|
PROSITE |
PS51571--SAM_MT43_PR_SET PS50280--SET
|
Pfam |
PF00856--SET
|
Gene Ontology |
GO:0005634--C:nucleus GO:0018024--F:histone-lysine N-methyltransferase activity GO:0009792--P:embryo development ending in birth or egg hatching GO:0006355--P:regulation of transcription, DNA-templated GO:0006351--P:transcription, DNA-templated
|
Orthology |
|
Created Date |
25-Jun-2016 |