WERAM Information

Tag Content
WERAM ID WERAM-Hos-0079
Ensembl Protein ID ENSP00000367024.4
Uniprot Accession Q86UY6; NAA40_HUMAN; B4DR03; B4DU10; Q5HYL5; Q9H897
Genbank Protein ID NP_001287729.1; NP_079047.2
Protein Name N-alpha-acetyltransferase 40
Genbank Nucleotide ID NM_001300800.1; NM_024771.3
Gene Name NAA40;NAT11;Patt1
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSG00000110583.12 ENST00000377793.8 ENSP00000367024.4
ENSG00000110583.12 ENST00000542163.1 ENSP00000442055.1
Details
Type Family Domain Substrates AA References (PMIDs)
HAT GCN5 N-acetyltransferase H2A; H4 K 24248912; 18327268; 21935442
Status Reviewed
Classification
Type Family E-value Score Start End
HAT GCN5 8.90e-52 177.7 65 216
Organism Homo sapiens
NCBI Taxa ID 9606
Functional Description
(View)		 Responsible for the acetylation of the N-terminal residues of histones H4 and H2A.
Domain Profile
  HAT GCN5
           GCN5.txt   2 leksrvdevl.lvlvglqkvfeaqlprmkkeyiarlladrkhkslvvikkdngvvggitfrlfeeegfvEvvyc...avaskervkGyGkrL 89 
                        le+++vd+++ l+++++q+++e++++++k+++++++++d+++++l+++++++++v++++fr f++e+++Ev+yc   +++sk+r+kG+Gk+L
  ENSP00000367024.4  65 LEPATVDWAFdLTKTNMQTMYEQSEWGWKDREKREEMTDDRAWYLIAWENSSVPVAFSHFR-FDVECGDEVLYCyevQLESKVRRKGLGKFL 155
                        899**********************************************************.****************************** PP
           GCN5.txt  90 lnhlkevarktrrikffLT.fadneaigyfkkqgfskeiklpksstigyikeyegatllec 149
                        +++l+ +a++t+++k++LT f++n+++++f+++++++ei+++++s++g+++e++++++l++
  ENSP00000367024.4 156 IQILQLMANSTQMKKVMLTvFKHNHGAYQFFREALQFEIDDSSPSMSGCCGEDCSYEILSR 216
                        ***********************************************************98 PP
Protein Sequence
(Fasta)		MGRKSSKAKE KKQKRLEERA AMDAVCAKVD AANRLGDPLE AFPVFKKYDR NGLNVSIECK 60
RVSGLEPATV DWAFDLTKTN MQTMYEQSEW GWKDREKREE MTDDRAWYLI AWENSSVPVA 120
FSHFRFDVEC GDEVLYCYEV QLESKVRRKG LGKFLIQILQ LMANSTQMKK VMLTVFKHNH 180
GAYQFFREAL QFEIDDSSPS MSGCCGEDCS YEILSRRTKF GDSHHSHAGG HCGGCCH 237
Nucleotide Sequence
(Fasta)		AGGGCCGTCC GCTCTGCTGC CGCCGCTGTT GCAGCCACCG CCGTTGCCGC CTCCCTGCCG 60
GCAAGTGTGT GAAGAAGAAG CTGAGCGTTG TCGCCGCCGC TATGGGGAGA AAGTCAAGCA 120
AAGCCAAGGA GAAGAAGCAG AAGCGGTTGG AGGAGCGAGC AGCCATGGAT GCCGTTTGTG 180
CCAAAGTGGA CGCTGCCAAC AGGCTTGGAG ACCCTCTGGA GGCTTTCCCA GTGTTCAAGA 240
AATATGATAG AAACGGGTTG AATGTCTCCA TTGAATGTAA GCGAGTGTCT GGACTGGAGC 300
CAGCCACCGT GGATTGGGCC TTCGACCTGA CCAAAACGAA TATGCAAACC ATGTATGAGC 360
AGAGCGAGTG GGGCTGGAAG GACCGAGAGA AACGGGAGGA AATGACAGAT GACCGAGCCT 420
GGTACCTCAT CGCGTGGGAA AACAGCTCCG TCCCTGTTGC CTTTTCTCAC TTCCGGTTTG 480
ACGTGGAGTG TGGGGATGAA GTCCTGTACT GCTATGAAGT GCAGTTGGAA AGCAAGGTGC 540
GGCGGAAAGG CCTGGGGAAG TTCCTCATAC AGATCCTGCA GCTCATGGCC AACAGCACAC 600
AGATGAAGAA GGTTATGTTA ACAGTATTTA AACACAATCA TGGTGCCTAC CAGTTCTTCA 660
GAGAAGCGTT GCAATTTGAA ATTGATGACT CTTCCCCCAG CATGTCCGGT TGCTGTGGGG 720
AGGATTGCTC CTATGAGATC CTGAGCCGGA GGACCAAGTT TGGGGACAGC CATCACTCCC 780
ACGCGGGTGG GCACTGTGGT GGCTGCTGCC ACTGAACTCT CAGAGCCACT TTCAAGTCAC 840
AATGCTCTCT CCTAAGGCCT TTCCTCTTTC CTGGTCTCAC TGTTCACCGG GTGTCCTCAG 900
AGCTGTGGCC TCCCCAGCCC TGCACGTGCC AGGCTGCGCC CTGAGAGCAC AGAACCCTGG 960
GGAGAAGTGG TATCAGCTGC TCCTCCTCTC CTAGGAGACC AGAGTGCTAG AAGGGAATGA 1020
AAGGGAGAGG GAAGAGTAGG TGGGGCCGGG CAGTGAAGCT CATCCTCCAC AGTGGCTGCC 1080
TCCTCATTTG GCTCCTGGGG CCTGCAGTGG AGGTTCTCGC ACCTCTGCAG CCCCTAGATT 1140
CCTGGCAACC TCCCCTCCCC TGACACATAC ACACTTGGAC AAATGGAATG TTTATGTCCA 1200
CCTTTATGAA AGTTCTGGAG TCCTGGGTCT GGGGTTTGCT GGTCCCCAAA GAGGAACACA 1260
CTGGGTGTAA GATCTGGGTG TAGAGGGCGG CTTCAGAGAG ACTCACGCTT GCGCAGTTGG 1320
AATTGCTGTT AACGGAGACT GGGAAGATCT TTTGTGCCAA GATGCAGGGA AATGAAGAAA 1380
GCTCTTTCCA GCTGTTTTTA TGGATTCATG GAGTGGGCTC ATGTTGGGAC CAGCTGACTC 1440
TGGGAGGAAG ACTGCCTCTC CATCGCTGTC AGAGAGCCTG AAAGGACCAA CAATGAGGTG 1500
TTCTTGGGAC CCGCCATGGG GATGATTGCT TCTCTAGGCT CCTGGATGTT GCTGCATTCT 1560
AAGCTTAACC TCCTGGTCTC ATGGCAGTGA CTTGAGCTTT TGATTCATAG AAGAAAGCCA 1620
GAGGTTCTGC TTGTTCTTGT CTGCCAGCCC TCGTCGTTCT TTCTCCTCTG CCTCTCACCT 1680
CTACCCCAAA TACCTCTGTT CTTAGTCTCA AGGGGAGAAT AACATCAGGG AGCCCCTCAT 1740
CTTCCCCAGA AGGACTTCTC GTTCCTCATG TAGTTAACTC CATTGATTTT CCTATCTTGG 1800
TGCTGATAGC TCTCTAAGGG TAGGGCACAC CTCCCCACAG CCACCCTCCC TCTTCAGAGA 1860
GCCCCCAGCC AGCAGCAGGC CCCTCTGCCT GCACTCCTCA GGCTTGCCCC TCGCTGCCTC 1920
AGTGAGGCAC TAGTGCCACT GCCGTGGCCC AGCCGGGCCA TAGCTCAGGC TGCAGCAGAA 1980
ATGCCTCTCA GTGGCCAACA GTTGCTTTTC TCTCTGGTGT CACCCTGTGG CAACAGGCTG 2040
GAGCAGGGGA AGGAGAAAGC CTTCCTCTTC TCTCATAGGA TAGAAAGGCA GGCTCAGAAC 2100
TAATGCTCAT CCTGATCTCT AGGCCTTGTT CCTCTTCCAG GGAAGAAAAG CCAAATCCTT 2160
ATCAAGGAAA AAGCACCTAA CAGCTCCCTT TGGATATCCC TGAGCTCTGC TGTGGGGAGT 2220
ATCATAAAGG TTCTAGCCTT CGTGAAGTTG TTCTCGTGGA GGTCTGTTGG TCCCTCTGAC 2280
CTCAGCATCT GCTCACATCC CACCCTCTGC CCAACTCTGG CAGTCTCTCC TGGCAGATCT 2340
CCCCAGAGTG GTCCTTGCTT CTCACCTGGA TTCCTGCTTG TGCAGGAGCC TGTGTACACA 2400
GGGCCTCCCT CACCCAGCCT GGCCCCTCTG CTGAGCACTT TGCGCTGCTC TTGATGGGCA 2460
GCAGTGGGAC TGGGAACTCC TTAGAGAGGG CCTTGCAGCT TTACACTGGA ATAAGTCTGC 2520
CTCTGCCTCT GCCTCACCCT GCTGGCTCCT GGTGGGTTTC ATCCCAGGCA GAGTTGACAT 2580
TGCTGGAGGG GTTTGGTGGA CTCCTAAGAA TCATGAAACC ACAGGAGCAT GTTTAGGAAG 2640
AGATTTGTCT CTGGTCCCTG TCTCTGAAAG GACACAGATG CTAAATATTT ATTGTCTTAG 2700
ATCATGGATT CCTGATACCT CTCACTCAAG GGGACCAAAA GGGACCCCCC CGTGTTCATC 2760
CCTTGTAAGG TGAGTTCAGT CTACGTTGTC TCTTTCCAGT CACTGGATAC GTGGCACCAA 2820
CTGGTCAATG GGTGCTTGGT GCCATACCCT GCTCACCCTA GTCTCTGCAG GCCATGTCCT 2880
GAAGGGTTCC TCAGGAGGTC GGGACTAGGG TGGGAGAGGC ACTATCTGAG ACCTGCAATC 2940
ACTCTTGTTG GTCTTGAGCC CATTCATTTC CAAAACATCC ATCTTTCTCC ACTTCCCCCA 3000
GGTCTTGGTT TTGAGAAACA GCAGGCATGG CTGAGTGCGG TGGCTTACAC CTGTAATCCC 3060
AGCACTTTGG GAGGCTGAGG CAGGCGGGTC ACCTGAGGTC AGGAGTTCAA GACCAGCCTG 3120
GTCAACATGG CAAAAGCCCA TCTCTACTAA AAAATACAAA AATCAGCCAG GCGTGGTTGT 3180
GGCCTGTAAT CCCAGCTACT CGGGAGGCTG AGGCAGGAGA CTCGCTTGAA CCCAGGAGGT 3240
GGAGGTTGTG GTGAGCTGAG ATCACGCCAT TGCACTCCAG CCTAGGCGAC AGAGTGAGAC 3300
TCCATCTCAA AAAAAAAAAA AAGAGAAACA TAGCAGGCCT TTTTTACCAG GCTTTTTGTG 3360
TTTTGTTTGT TTGTTTGGAG CATGTTAAGA TTTTTTTAAG ATTTTTAAAA TTTTAGTTAT 3420
ATCCACCCTA TTTCAGGTTA TTTTTGTTGG TGTCAAGTAT GTATAGGACA TGTGAATGGT 3480
TCTTTTTAAT TTTTTTTTAA GAGGAAATTT GGAAGATAAA CTCCTTGATA TATATATATA 3540
TATATATATT TTTTTTTTTC TTTAGCAGCT TGTTATCACT GGAATCAAAG GGAAAAAGTG 3600
ATCTCTTCTT GCATTGGTTG TATTTGTATG TCACAAATAA AAGACACTTT GGTCAGCTGC 3660
TGAG 3665
Sequence Source Ensembl
Keyword

KW-0002--3D-structure
KW-0012--Acyltransferase
KW-0025--Alternative splicing
KW-0181--Complete proteome
KW-0449--Lipoprotein
KW-0519--Myristate
KW-1185--Reference proteome
KW-0808--Transferase
--
Interpro

IPR016181--Acyl_CoA_acyltransferase
IPR000182--GNAT_dom
PROSITE

PS51186--GNAT
Pfam

PF00583--Acetyltransf_1
Gene Ontology

GO:0008080--F:N-acetyltransferase activity
GO:0006629--P:lipid metabolic process
Orthology
WERAM ID Ensembl Protein ID Species Identity E-value Score
WERAM-Nol-0048 ENSNLEP00000005731.2 Nomascus leucogenys 100 9e-119 423
WERAM-Paa-0016 ENSPANP00000006090.1 Papio anubis 100 4e-118 421
WERAM-Ict-0100 ENSSTOP00000010199.2 Ictidomys tridecemlineatus 100 4e-118 421
WERAM-Pat-0027 ENSPTRP00000048005.3 Pan troglodytes 100 4e-118 421
WERAM-Mum-0061 ENSMUSP00000025675.9 Mus musculus 100 5e-118 420
WERAM-Chs-0079 ENSCSAP00000003174.1 Chlorocebus sabaeus 100 5e-118 420
WERAM-Dio-0106 ENSDORP00000010591.1 Dipodomys ordii 100 8e-118 419
WERAM-Otg-0137 ENSOGAP00000011979.2 Otolemur garnettii 99 1e-117 419
WERAM-Gog-0203 ENSGGOP00000025168.1 Gorilla gorilla 100 1e-117 419
WERAM-Eqc-0007 ENSECAP00000000886.1 Equus caballus 100 1e-117 419
WERAM-Tut-0118 ENSTTRP00000009683.1 Tursiops truncatus 100 2e-117 418
WERAM-Orc-0162 ENSOCUP00000014248.2 Oryctolagus cuniculus 99 3e-117 417
WERAM-Ova-0033 ENSOARP00000004288.1 Ovis aries 99 5e-117 417
WERAM-Ran-0143 ENSRNOP00000028759.4 Rattus norvegicus 98 5e-117 417
WERAM-Bot-0040 ENSBTAP00000003996.5 Bos taurus 99 5e-117 417
WERAM-Caf-0152 ENSCAFP00000033848.2 Canis familiaris 99 6e-117 417
WERAM-Caj-0194 ENSCJAP00000033903.2 Callithrix jacchus 99 6e-117 417
WERAM-Fec-0143 ENSFCAP00000013599.3 Felis catus 99 7e-117 416
WERAM-Mup-0153 ENSMPUP00000013219.1 Mustela putorius furo 99 9e-117 416
WERAM-Cap-0019 ENSCPOP00000001710.2 Cavia porcellus 98 1e-116 416
WERAM-Sus-0157 ENSSSCP00000019658.1 Sus scrofa 98 1e-116 416
WERAM-Aim-0209 ENSAMEP00000019122.1 Ailuropoda melanoleuca 98 3e-116 414
WERAM-Dan-0149 ENSDNOP00000027273.1 Dasypus novemcinctus 98 4e-116 414
WERAM-Ect-0109 ENSETEP00000012191.1 Echinops telfairi 97 1e-114 409
WERAM-Pes-0064 ENSPSIP00000008438.1 Pelodiscus sinensis 95 2e-113 405
WERAM-Mod-0068 ENSMODP00000010981.2 Monodelphis domestica 94 5e-113 404
WERAM-Sah-0051 ENSSHAP00000005909.1 Sarcophilus harrisii 94 2e-112 402
WERAM-Mae-0119 ENSMEUP00000011722.1 Macropus eugenii 94 2e-112 402
WERAM-Anc-0134 ENSACAP00000012199.3 Anolis carolinensis 91 3e-109 391
WERAM-Mam-0173 ENSMMUP00000024510.2 Macaca mulatta 99 5e-109 390
WERAM-Myl-0138 ENSMLUP00000011141.2 Myotis lucifugus 94 5e-108 387
WERAM-Poa-0031 ENSPPYP00000003607.1 Pongo abelii 93 9e-107 383
WERAM-Soa-0028 ENSSARP00000002815.1 Sorex araneus 93 7e-92 333
Created Date 25-Jun-2016