WERAM Information

Tag Content
WERAM ID WERAM-Mum-0061
Ensembl Protein ID ENSMUSP00000025675.9
Uniprot Accession Q8VE10; NAA40_MOUSE; Q3V3R7; Q6PE89; Q9D4I5
Genbank Protein ID NP_081919.1
Protein Name N-alpha-acetyltransferase 40
Genbank Nucleotide ID NM_027643.1
Gene Name NAA40;NAT11;Patt1
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSMUSG00000024764.9 ENSMUST00000025675.9 ENSMUSP00000025675.9
Details
Type Family Domain Substrates AA References (PMIDs)
HAT GCN5 N-acetyltransferase K 22231784
Status Reviewed
Classification
Type Family E-value Score Start End
HAT GCN5 5.30e-52 177.6 65 216
Organism Mus musculus
NCBI Taxa ID 10090
Functional Description
(View)		 Responsible for the acetylation of the N-terminal residues of histones H4 and H2A.
Domain Profile
  HAT GCN5
              GCN5.txt   2 leksrvdevl.lvlvglqkvfeaqlprmkkeyiarlladrkhkslvvikkdngvvggitfrlfeeegfvEvvyc...avaskervkGyG 86 
                           le+++vd+++ l+++++q+++e++++++k+++++++++d+++++l+++++++++v++++fr f++e+++Ev+yc   +++sk+r+kG+G
  ENSMUSP00000025675.9  65 LEPATVDWAFdLTKTNMQTMYEQSEWGWKDREKREEMTDDRAWYLIAWENSSIPVAFSHFR-FDVECGDEVLYCyevQLESKVRRKGLG 152
                           899**********************************************************.*************************** PP
              GCN5.txt  87 krLlnhlkevarktrrikffLT.fadneaigyfkkqgfskeiklpksstigyikeyegatllec 149
                           k+L+++l+ +a++t+++k++LT f++n+++++f+++++++ei+++++s++g+++e++++++l++
  ENSMUSP00000025675.9 153 KFLIQILQLMANSTQMKKVMLTvFKHNHGAYQFFREALQFEIDDSSPSMSGCCGEDCSYEILSR 216
                           **************************************************************98 PP
Protein Sequence
(Fasta)		MGRKSSKAKE KKQKRLEERA AMDAVCAKVD AANRLGDPLE AFPVFKKYDR NGLNVSIECK 60
RVSGLEPATV DWAFDLTKTN MQTMYEQSEW GWKDREKREE MTDDRAWYLI AWENSSIPVA 120
FSHFRFDVEC GDEVLYCYEV QLESKVRRKG LGKFLIQILQ LMANSTQMKK VMLTVFKHNH 180
GAYQFFREAL QFEIDDSSPS MSGCCGEDCS YEILSRRTKF GDSQHSHTGG HCGGCCH 237
Nucleotide Sequence
(Fasta)		ATTCCTAGCG CGACGCTCTG CCGCGCCTCC CGCCTTTCTG TTCTCAGGCC TTCCGCGCGC 60
ACGGCAACCG TTCCACCTGC GCGCCTTCGC GCTCGCCGCC CACTCTGGTC CGGTTCTGCG 120
CCGGCGCGGG GCCCTCTAGG ACGCGCGGGG GATTTGTGAG ACGCATGCGT AGTGCGCGGC 180
CGGCCGCTTC GCTGTCGCTC GGGTTCCGCC GTTGCCACCT CCCTACGGGC AAGTGCGAGA 240
GGGGAGCCGA GGGCCGCCGC CGTCGCCGCC GCCGCCACCA TGGGGAGAAA GTCGAGCAAA 300
GCCAAAGAGA AGAAGCAGAA ACGATTGGAG GAGAGAGCGG CCATGGATGC TGTGTGTGCC 360
AAAGTGGATG CTGCCAACAG GCTTGGAGAC CCTCTGGAGG CATTCCCAGT CTTCAAGAAG 420
TATGACCGCA ATGGGTTGAA TGTCTCCATT GAATGTAAGC GAGTGTCTGG ATTGGAGCCA 480
GCCACTGTGG ACTGGGCCTT CGACCTGACC AAAACCAATA TGCAGACGAT GTATGAGCAA 540
AGTGAGTGGG GCTGGAAGGA CCGAGAAAAA CGGGAGGAAA TGACCGATGA CCGAGCCTGG 600
TACCTCATTG CTTGGGAAAA CAGTTCCATC CCAGTTGCCT TTTCTCACTT CCGGTTTGAT 660
GTGGAGTGCG GGGATGAAGT CCTGTACTGC TATGAAGTGC AGCTGGAAAG CAAGGTACGG 720
CGGAAAGGCC TAGGGAAGTT CCTCATTCAG ATCCTGCAGC TCATGGCCAA CAGCACACAG 780
ATGAAGAAGG TGATGTTAAC TGTTTTTAAA CATAATCATG GCGCCTATCA GTTCTTCCGA 840
GAGGCACTGC AGTTTGAAAT TGATGACTCT TCACCCAGCA TGTCTGGTTG CTGTGGGGAG 900
GACTGTTCCT ATGAGATTCT GAGCCGGAGG ACCAAGTTCG GGGACAGTCA GCACTCCCAC 960
ACAGGCGGCC ACTGTGGTGG CTGTTGCCAC TGAACTCCTA GAACCACTTT GAAGGGATGT 1020
CACTCTCCTT AGGCCTGTCC CCTCCCTGGT CTTATGCCAC TTGCCAGGTA CCCTCAGAGC 1080
TGTGGGGTGC CTTAGTTCTG CGTGAGCCAG GCATATCCTG AGAACACAGA ACCTTGGGGA 1140
GCAGTGACCC CAGCTGCCTT TCCACCTCCC TCCTGGAAAA GCAGAGTGCC AGGAGGGAGC 1200
ACCGAGGAGA GGGTGCCGTG AGATTGACAG GTTGGCTGTC AAGCTCATCC TTGTGCAGTA 1260
GCTGCCTACT TACTTAGTTC TTGGGCCCCT AAAATGGAAG GCTTCCCTCT TGTCTGCAGC 1320
TGAGTTCCTG ACCGGGTTGC ACACCATGCC CCATATGGAC AAATGGAATG TTGTTAATAC 1380
CCACGTTTGT AAAAGGCCTG GAGTCTGCTG GTCCCCAGAA AGAACTGGAT GCAAATCTGG 1440
GCATACAACA GACCTTGGAC ATCTTTTCTC TGGGGACAAA GTGCTCTTTC AGAGACCATG 1500
TAGCCCTTGA TGTCAAGGTG CAAAGGTTTG CACTGTAATC TTATAGATCC ACAGGTGGTG 1560
TCTCGGGACC AGCCAACTTC AGGAGGGAGT CTGCCTCCAC CACTGTCAGT AAGACAGGAT 1620
CAGGAAGAGC TGTCTCTTAC GTGTTTGTCA TAGGGATGTG GCATCTCTGG GCCTTTGGAC 1680
TTTGCTGCAT TTTCATGATC TTGACTTGAC CTTTTTATTC AAGAAGGAAG TCAAAGTCCT 1740
GCCTGTTCTC ACACCTCTCT TCTCAGCCCA GATACCTCTG TTCTTAGTCT CAAGGGGAAC 1800
AACATCAGGG AGCCTCTCGT CTTCCCCAGA AGAACCCTTC CTTCCTGGTA TAGCTGAATC 1860
CATTTCTTCC TATTCTTGGT GCTGATAGCT CTCTGAAGGT GGGGTACTTC CCTGCCACCC 1920
TCCCTGACTG AGGGGCCCCA GCCAGCAGCA GGCCCCTTTG CCTGTTCTCC CGAGCCCCAC 1980
CCCTCACCGC CTCAATGAGG CACTCGTGCC ACTGTCTTGG CACCCCTGGG ATGCCTTTCA 2040
GTGGCGTACC ACTGCTTTCC TGTCATGGGT GTCACCCTAC AGTGACAGGC TAGAGCCAGA 2100
AGGCCTTCCT CCTCAGGGGA TACAGGCTTA GAACTTGAAC TCGCCCTGAC CTCTGGATCC 2160
TGTTCTTCAA GGAAGCAAAA CCAAATCCTT ACCTAGAAAA ACAGACTTGC CACTTCCCCA 2220
TTGCTGCCCC TGAGTTCCGC CTTGGGAGGC GTGGCAGAGA GCTTGCCTTT GTGCAGTTGC 2280
TTTCAGAGAC TCTGCTACCG AGCTGAGTCT GTTCACCTTA CCCAGCCTGA CTCAGCTGTC 2340
TGTTCTGGCA AGTCTCCCCA AAGGAGTCAC CTCTCGCCCA GATCCTTGGC TTGTGCAGTA 2400
GCCTGGACTC AGAGAGTCCT TTCTTGCTTG GTCTGTCCGC TGTTGAACAC TCTGTGCTGT 2460
TGTTAGCCCT TGGCCTTGCC TGGGAGAAGG CCTTGCAGCT TTACACTGGA ATAGGTCTGC 2520
TTTTGTCTGG CTTGCTAGCT TCTGGGCTAT ACCTCTGGTG AGAGTTGGAG CTGCCCAGAA 2580
GGGATTGGCA TGCTCCTTCC GAGAATCATG AGACAGGAGC ATGCTTGCAG GAGTTATTCC 2640
CTAATCTCTG TCTGTCTTAG ATCATGAATC TCTGATACCT CCTACTTAGG GGTCCAGAAG 2700
GAACCCCCAG TGTAAGCCCC ATGTAAGGTG AATAGAGTGT CTCGTCTCCA GTTACTGGAC 2760
ACCCAGCACC AGGACTCATG GTGCTCAGTG CCTGCCCTGC TCCCCACCCT CTGCAGGCCC 2820
CATCCCAAAG GGCCCTTCAG GATCTCTCAC TGGACCAGCG GGATGGTGGC CAAGACCAGC 2880
AGATTACTCC TGTGGGTGTT AAGCCCAGTG GTTCATCAGG CATCGTCTAC CGCCCTCTTG 2940
TTTTGAGAAA CAGCAGGTCT AATCTACTGT ACCAGGCTCT TTTGCTTTTT GTTCCAGGAG 3000
TGTTAAAATG GTTTTAAAAG TTTTCGTTTT GTTTTAGTGA ACCTATTCCA TTTCAGGTTA 3060
TTTTTGTTGC TGTTAAATGT TTATGGTTCT TTTTAACCTT TTCTGGAGGG TTGGGGGGTT 3120
ATTTTTGTTT TTAAGAGGAA AGTTGGAAGG TAATTTTGTT TTATATTTTT TTTCCTAGCA 3180
GTTCATTATC ACTGGAATCA AAGGGAAAAA AACCATCTCT CTTTGTATCC ATTTTATTTG 3240
TATGTCATTA ATAAACAGAT ACTTTGTGCA GATGC 3276
Sequence Source Ensembl
Keyword

KW-0012--Acyltransferase
KW-0025--Alternative splicing
KW-0181--Complete proteome
KW-0449--Lipoprotein
KW-0519--Myristate
KW-1185--Reference proteome
KW-0808--Transferase
--
Interpro

IPR016181--Acyl_CoA_acyltransferase
IPR000182--GNAT_dom
PROSITE

PS51186--GNAT
Pfam

PF00583--Acetyltransf_1
Gene Ontology

GO:0008080--F:N-acetyltransferase activity
GO:0006629--P:lipid metabolic process
Orthology
WERAM ID Ensembl Protein ID Species Identity E-value Score
WERAM-Nol-0048 ENSNLEP00000005731.2 Nomascus leucogenys 99 1e-120 429
WERAM-Paa-0016 ENSPANP00000006090.1 Papio anubis 100 2e-120 428
WERAM-Otg-0137 ENSOGAP00000011979.2 Otolemur garnettii 100 2e-120 428
WERAM-Ict-0100 ENSSTOP00000010199.2 Ictidomys tridecemlineatus 100 2e-120 428
WERAM-Chs-0079 ENSCSAP00000003174.1 Chlorocebus sabaeus 99 3e-120 428
WERAM-Dio-0106 ENSDORP00000010591.1 Dipodomys ordii 100 5e-120 427
WERAM-Pat-0027 ENSPTRP00000048005.3 Pan troglodytes 99 7e-120 426
WERAM-Hos-0079 ENSP00000367024.4 Homo sapiens 99 7e-120 426
WERAM-Eqc-0007 ENSECAP00000000886.1 Equus caballus 99 9e-120 426
WERAM-Tut-0118 ENSTTRP00000009683.1 Tursiops truncatus 99 9e-120 426
WERAM-Ran-0143 ENSRNOP00000028759.4 Rattus norvegicus 99 1e-119 426
WERAM-Ova-0033 ENSOARP00000004288.1 Ovis aries 99 1e-119 425
WERAM-Gog-0203 ENSGGOP00000025168.1 Gorilla gorilla 99 2e-119 425
WERAM-Orc-0162 ENSOCUP00000014248.2 Oryctolagus cuniculus 99 2e-119 425
WERAM-Bot-0040 ENSBTAP00000003996.5 Bos taurus 99 3e-119 424
WERAM-Caj-0194 ENSCJAP00000033903.2 Callithrix jacchus 99 3e-119 424
WERAM-Fec-0143 ENSFCAP00000013599.3 Felis catus 99 4e-119 424
WERAM-Mup-0153 ENSMPUP00000013219.1 Mustela putorius furo 99 4e-119 424
WERAM-Caf-0152 ENSCAFP00000033848.2 Canis familiaris 99 4e-119 424
WERAM-Cap-0019 ENSCPOP00000001710.2 Cavia porcellus 98 5e-119 424
WERAM-Sus-0157 ENSSSCP00000019658.1 Sus scrofa 98 8e-119 423
WERAM-Dan-0149 ENSDNOP00000027273.1 Dasypus novemcinctus 99 1e-118 422
WERAM-Aim-0209 ENSAMEP00000019122.1 Ailuropoda melanoleuca 98 1e-118 422
WERAM-Ect-0109 ENSETEP00000012191.1 Echinops telfairi 97 4e-117 417
WERAM-Mod-0068 ENSMODP00000010981.2 Monodelphis domestica 94 3e-115 411
WERAM-Pes-0064 ENSPSIP00000008438.1 Pelodiscus sinensis 94 4e-115 410
WERAM-Sah-0051 ENSSHAP00000005909.1 Sarcophilus harrisii 94 5e-115 410
WERAM-Mae-0119 ENSMEUP00000011722.1 Macropus eugenii 94 7e-115 410
WERAM-Mam-0173 ENSMMUP00000024510.2 Macaca mulatta 98 2e-111 398
WERAM-Anc-0134 ENSACAP00000012199.3 Anolis carolinensis 91 2e-111 398
WERAM-Myl-0138 ENSMLUP00000011141.2 Myotis lucifugus 94 3e-110 395
WERAM-Poa-0031 ENSPPYP00000003607.1 Pongo abelii 93 1e-108 389
WERAM-Soa-0028 ENSSARP00000002815.1 Sorex araneus 94 4e-94 341
Created Date 25-Jun-2016